Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of allg-iPS cell mice from terminally differentiated B cells

Nature Genetics

Volumn 44, Issue 4, 2012, Pages 398-405

  Stadtfeld, Matthias ^a,b,j   Apostolou, Effie ^a,b   Ferrari, Francesco ^c   Choi, Jiho ^a,b   Walsh, Ryan M ^a,b   Chen, Taiping ^e   Ooi, Steen S K ^f,g   Kim, Sang Yong ^h   Bestor, Timothy H ^g   Shioda, Toshi ^a   Park, Peter J ^c,d   Hochedlinger, Konrad ^a,b,i  

^a MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^b Harvard University   (United States)

^c Harvard Medical School Center for Biomedical Informatics   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

^g University College London Cancer Institute ^*  (United States)

^h Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

ⁱ MASSACHUSETTS GENERAL HOSPITAL   (United States)

^j NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; DLK1 DIO3 PROTEIN; DNA METHYLTRANSFERASE 3A; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL TYPE; CHROMATIN; DNA METHYLATION; EMBRYONIC STEM CELL; GENE CLUSTER; GENE SILENCING; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL;

ANIMALS; ASCORBIC ACID; B-LYMPHOCYTES; CELL DIFFERENTIATION; CHROMATIN; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; GENOMIC IMPRINTING; INDUCED PLURIPOTENT STEM CELLS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; NUCLEAR REPROGRAMMING; OCTAMER TRANSCRIPTION FACTOR-3; PROMOTER REGIONS, GENETIC; PROTEINS;

ANIMALIA; IPS; MUS;

EID: 84862777034     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.1110     Document Type: Article

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