-
1
-
-
0032830639
-
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
-
Amir R.E., Van den Veyver I.B., Wan M., Tran C.Q., Francke U., Zoghbi H.Y. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet. 1999, 23:185-188.
-
(1999)
Nat. Genet.
, vol.23
, pp. 185-188
-
-
Amir, R.E.1
Van den Veyver, I.B.2
Wan, M.3
Tran, C.Q.4
Francke, U.5
Zoghbi, H.Y.6
-
2
-
-
33846933274
-
Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation
-
Barreto G., Schafer A., Marhold J., Stach D., Swaminathan S.K., Handa V., Doderlein G., Maltry N., Wu W., Lyko F., Niehrs C. Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 2007, 445:671-675.
-
(2007)
Nature
, vol.445
, pp. 671-675
-
-
Barreto, G.1
Schafer, A.2
Marhold, J.3
Stach, D.4
Swaminathan, S.K.5
Handa, V.6
Doderlein, G.7
Maltry, N.8
Wu, W.9
Lyko, F.10
Niehrs, C.11
-
3
-
-
40549110266
-
Investigating genotype-phenotype relationships in Rett syndrome using an international data set
-
Bebbington A., Anderson A., Ravine D., Fyfe S., Pineda M., de Klerk N., Ben-Zeev B., Yatawara N., Percy A., Kaufmann W.E., Leonard H. Investigating genotype-phenotype relationships in Rett syndrome using an international data set. Neurology 2008, 70:868-875.
-
(2008)
Neurology
, vol.70
, pp. 868-875
-
-
Bebbington, A.1
Anderson, A.2
Ravine, D.3
Fyfe, S.4
Pineda, M.5
de Klerk, N.6
Ben-Zeev, B.7
Yatawara, N.8
Percy, A.9
Kaufmann, W.E.10
Leonard, H.11
-
4
-
-
78649232442
-
Genetics of Alzheimer disease
-
Bekris L.M., Yu C.E., Bird T.D., Tsuang D.W. Genetics of Alzheimer disease. J. Geriatr. Psychiatry Neurol. 2010, 23:213-227.
-
(2010)
J. Geriatr. Psychiatry Neurol.
, vol.23
, pp. 213-227
-
-
Bekris, L.M.1
Yu, C.E.2
Bird, T.D.3
Tsuang, D.W.4
-
5
-
-
54849422301
-
Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner
-
Benn C.L., Sun T., Sadri-Vakili G., McFarland K.N., DiRocco D.P., Yohrling G.J., Clark T.W., Bouzou B., Cha J.H. Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner. J. Neurosci. 2008, 28:10720-10733.
-
(2008)
J. Neurosci.
, vol.28
, pp. 10720-10733
-
-
Benn, C.L.1
Sun, T.2
Sadri-Vakili, G.3
McFarland, K.N.4
DiRocco, D.P.5
Yohrling, G.J.6
Clark, T.W.7
Bouzou, B.8
Cha, J.H.9
-
6
-
-
64349095390
-
An operational definition of epigenetics
-
Berger S.L., Kouzarides T., Shiekhattar R., Shilatifard A. An operational definition of epigenetics. Genes Dev. 2009, 23:781-783.
-
(2009)
Genes Dev.
, vol.23
, pp. 781-783
-
-
Berger, S.L.1
Kouzarides, T.2
Shiekhattar, R.3
Shilatifard, A.4
-
7
-
-
84861145950
-
Do epigenetic pathways initiate late onset Alzheimer disease (LOAD): towards a new paradigm
-
Bihaqi S.W., Schumacher A., Maloney B., Lahiri D.K., Zawia N.H. Do epigenetic pathways initiate late onset Alzheimer disease (LOAD): towards a new paradigm. Curr. Alzheimer Res. 2012, 9:574-588.
-
(2012)
Curr. Alzheimer Res.
, vol.9
, pp. 574-588
-
-
Bihaqi, S.W.1
Schumacher, A.2
Maloney, B.3
Lahiri, D.K.4
Zawia, N.H.5
-
9
-
-
69249220176
-
DNA methylation and methyl-CpG binding proteins: developmental requirements and function
-
Bogdanovic O., Veenstra G.J. DNA methylation and methyl-CpG binding proteins: developmental requirements and function. Chromosoma 2009, 118:549-565.
-
(2009)
Chromosoma
, vol.118
, pp. 549-565
-
-
Bogdanovic, O.1
Veenstra, G.J.2
-
10
-
-
33747880446
-
Lowered DNA methyltransferase (DNMT-3b) mRNA expression is associated with genomic DNA hypermethylation in patients with chronic alcoholism
-
Bonsch D., Lenz B., Fiszer R., Frieling H., Kornhuber J., Bleich S. Lowered DNA methyltransferase (DNMT-3b) mRNA expression is associated with genomic DNA hypermethylation in patients with chronic alcoholism. J. Neural Transm. 2006, 113:1299-1304.
-
(2006)
J. Neural Transm.
, vol.113
, pp. 1299-1304
-
-
Bonsch, D.1
Lenz, B.2
Fiszer, R.3
Frieling, H.4
Kornhuber, J.5
Bleich, S.6
-
11
-
-
84861221693
-
Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution
-
Booth M.J., Branco M.R., Ficz G., Oxley D., Krueger F., Reik W., Balasubramanian S. Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science 2012, 336:934-937.
-
(2012)
Science
, vol.336
, pp. 934-937
-
-
Booth, M.J.1
Branco, M.R.2
Ficz, G.3
Oxley, D.4
Krueger, F.5
Reik, W.6
Balasubramanian, S.7
-
12
-
-
34648833002
-
UHRF1 plays a role in maintaining DNA methylation in mammalian cells
-
Bostick M., Kim J.K., Esteve P.O., Clark A., Pradhan S., Jacobsen S.E. UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science 2007, 317:1760-1764.
-
(2007)
Science
, vol.317
, pp. 1760-1764
-
-
Bostick, M.1
Kim, J.K.2
Esteve, P.O.3
Clark, A.4
Pradhan, S.5
Jacobsen, S.E.6
-
13
-
-
84888133742
-
Epigenetic changes in the progression of Alzheimer's disease
-
Bradley-Whitman M.A., Lovell M.A. Epigenetic changes in the progression of Alzheimer's disease. Mech. Ageing Dev. 2013, 134:486-495.
-
(2013)
Mech. Ageing Dev.
, vol.134
, pp. 486-495
-
-
Bradley-Whitman, M.A.1
Lovell, M.A.2
-
14
-
-
84874936217
-
Mechanisms and therapeutic challenges in autism spectrum disorders: insights from Rett syndrome
-
Castro J., Mellios N., Sur M. Mechanisms and therapeutic challenges in autism spectrum disorders: insights from Rett syndrome. Curr. Opin. Neurol. 2013, 26:154-159.
-
(2013)
Curr. Opin. Neurol.
, vol.26
, pp. 154-159
-
-
Castro, J.1
Mellios, N.2
Sur, M.3
-
15
-
-
0345269738
-
Upstream stimulatory factors are mediators of Ca2+-responsive transcription in neurons
-
Chen W.G., West A.E., Tao X., Corfas G., Szentirmay M.N., Sawadogo M., Vinson C., Greenberg M.E. Upstream stimulatory factors are mediators of Ca2+-responsive transcription in neurons. J. Neurosci. 2003, 23:2572-2581.
-
(2003)
J. Neurosci.
, vol.23
, pp. 2572-2581
-
-
Chen, W.G.1
West, A.E.2
Tao, X.3
Corfas, G.4
Szentirmay, M.N.5
Sawadogo, M.6
Vinson, C.7
Greenberg, M.E.8
-
16
-
-
84866940776
-
The mammalian de novo DNA methyltransferases DNMT3A and DNMT3B are also DNA 5-hydroxymethylcytosine dehydroxymethylases
-
Chen C.C., Wang K.Y., Shen C.K. The mammalian de novo DNA methyltransferases DNMT3A and DNMT3B are also DNA 5-hydroxymethylcytosine dehydroxymethylases. J. Biol. Chem. 2012, 287:33116-33121.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 33116-33121
-
-
Chen, C.C.1
Wang, K.Y.2
Shen, C.K.3
-
17
-
-
84862994335
-
Effect of aging on 5-hydroxymethylcytosine in the mouse hippocampus
-
Chen H., Dzitoyeva S., Manev H. Effect of aging on 5-hydroxymethylcytosine in the mouse hippocampus. Restor. Neurol. Neurosci. 2012, 30:237-245.
-
(2012)
Restor. Neurol. Neurosci.
, vol.30
, pp. 237-245
-
-
Chen, H.1
Dzitoyeva, S.2
Manev, H.3
-
18
-
-
84875409508
-
DNA methylation program in developing hippocampus and its alteration by alcohol
-
Chen Y., Ozturk N.C., Zhou F.C. DNA methylation program in developing hippocampus and its alteration by alcohol. PLoS ONE 2013, 8:e60503.
-
(2013)
PLoS ONE
, vol.8
, pp. e60503
-
-
Chen, Y.1
Ozturk, N.C.2
Zhou, F.C.3
-
19
-
-
84897994794
-
Diversity of two forms of DNA methylation in the brain
-
Chen Y., Damayanti N.P., Irudayaraj J., Dunn K., Zhou F.C. Diversity of two forms of DNA methylation in the brain. Front. Genet. 2014, 5:46.
-
(2014)
Front. Genet.
, vol.5
, pp. 46
-
-
Chen, Y.1
Damayanti, N.P.2
Irudayaraj, J.3
Dunn, K.4
Zhou, F.C.5
-
20
-
-
84903362440
-
Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain
-
Coppieters N., Dieriks B.V., Lill C., Faull R.L., Curtis M.A., Dragunow M. Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain. Neurobiol. Aging 2014, 35(6):1334-1344.
-
(2014)
Neurobiol. Aging
, vol.35
, Issue.6
, pp. 1334-1344
-
-
Coppieters, N.1
Dieriks, B.V.2
Lill, C.3
Faull, R.L.4
Curtis, M.A.5
Dragunow, M.6
-
21
-
-
79959937861
-
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
-
Cortellino S., Xu J., Sannai M., Moore R., Caretti E., Cigliano A., Le Coz M., Devarajan K., Wessels A., Soprano D., Abramowitz L.K., Bartolomei M.S., Rambow F., Bassi M.R., Bruno T., Fanciulli M., Renner C., Klein-Szanto A.J., Matsumoto Y., Kobi D., Davidson I., Alberti C., Larue L., Bellacosa A. Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell 2011, 146:67-79.
-
(2011)
Cell
, vol.146
, pp. 67-79
-
-
Cortellino, S.1
Xu, J.2
Sannai, M.3
Moore, R.4
Caretti, E.5
Cigliano, A.6
Le Coz, M.7
Devarajan, K.8
Wessels, A.9
Soprano, D.10
Abramowitz, L.K.11
Bartolomei, M.S.12
Rambow, F.13
Bassi, M.R.14
Bruno, T.15
Fanciulli, M.16
Renner, C.17
Klein-Szanto, A.J.18
Matsumoto, Y.19
Kobi, D.20
Davidson, I.21
Alberti, C.22
Larue, L.23
Bellacosa, A.24
more..
-
22
-
-
46449128469
-
SMAD proteins control DROSHA-mediated microRNA maturation
-
Davis B.N., Hilyard A.C., Lagna G., Hata A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 2008, 454:56-61.
-
(2008)
Nature
, vol.454
, pp. 56-61
-
-
Davis, B.N.1
Hilyard, A.C.2
Lagna, G.3
Hata, A.4
-
23
-
-
84859454582
-
Wild-type microglia arrest pathology in a mouse model of Rett syndrome
-
Derecki N.C., Cronk J.C., Lu Z., Xu E., Abbott S.B., Guyenet P.G., Kipnis J. Wild-type microglia arrest pathology in a mouse model of Rett syndrome. Nature 2012, 484:105-109.
-
(2012)
Nature
, vol.484
, pp. 105-109
-
-
Derecki, N.C.1
Cronk, J.C.2
Lu, Z.3
Xu, E.4
Abbott, S.B.5
Guyenet, P.G.6
Kipnis, J.7
-
24
-
-
84866104895
-
Upregulation of TET1 and downregulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients
-
Dong E., Gavin D.P., Chen Y., Davis J. Upregulation of TET1 and downregulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients. Transl. Psychiatr. 2012, 2:e159.
-
(2012)
Transl. Psychiatr.
, vol.2
, pp. e159
-
-
Dong, E.1
Gavin, D.P.2
Chen, Y.3
Davis, J.4
-
25
-
-
69349098474
-
Epigenetics: definition, mechanisms and clinical perspective
-
Dupont C., Armant D.R., Brenner C.A. Epigenetics: definition, mechanisms and clinical perspective. Semin. Reprod. Med. 2009, 27:351-357.
-
(2009)
Semin. Reprod. Med.
, vol.27
, pp. 351-357
-
-
Dupont, C.1
Armant, D.R.2
Brenner, C.A.3
-
26
-
-
79956323623
-
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
-
Ficz G., Branco M.R., Seisenberger S., Santos F., Krueger F., Hore T.A., Marques C.J., Andrews S., Reik W. Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 2011, 473:398-402.
-
(2011)
Nature
, vol.473
, pp. 398-402
-
-
Ficz, G.1
Branco, M.R.2
Seisenberger, S.3
Santos, F.4
Krueger, F.5
Hore, T.A.6
Marques, C.J.7
Andrews, S.8
Reik, W.9
-
27
-
-
79551635700
-
Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1
-
Frauer C., Rottach A., Meilinger D., Bultmann S., Fellinger K., Hasenoder S., Wang M., Qin W., Soding J., Spada F., Leonhardt H. Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1. PLoS ONE 2011, 6:e16627.
-
(2011)
PLoS ONE
, vol.6
, pp. e16627
-
-
Frauer, C.1
Rottach, A.2
Meilinger, D.3
Bultmann, S.4
Fellinger, K.5
Hasenoder, S.6
Wang, M.7
Qin, W.8
Soding, J.9
Spada, F.10
Leonhardt, H.11
-
28
-
-
84856031137
-
Growth arrest and DNA-damage-inducible, beta (GADD45b)-mediated DNA demethylation in major psychosis
-
Gavin D.P., Sharma R.P., Chase K.A., Matrisciano F., Dong E., Guidotti A. Growth arrest and DNA-damage-inducible, beta (GADD45b)-mediated DNA demethylation in major psychosis. Neuropsychopharmacology 2012, 37:531-542.
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 531-542
-
-
Gavin, D.P.1
Sharma, R.P.2
Chase, K.A.3
Matrisciano, F.4
Dong, E.5
Guidotti, A.6
-
29
-
-
33846924001
-
Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2
-
Giacometti E., Luikenhuis S., Beard C., Jaenisch R. Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:1931-1936.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 1931-1936
-
-
Giacometti, E.1
Luikenhuis, S.2
Beard, C.3
Jaenisch, R.4
-
30
-
-
0034081681
-
The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease
-
Glass M., Dragunow M., Faull R.L. The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease. Neuroscience 2000, 97:505-519.
-
(2000)
Neuroscience
, vol.97
, pp. 505-519
-
-
Glass, M.1
Dragunow, M.2
Faull, R.L.3
-
31
-
-
78650826181
-
Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates
-
Globisch D., Munzel M., Muller M., Michalakis S., Wagner M., Koch S., Bruckl T., Biel M., Carell T. Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates. PLoS ONE 2010, 5:e15367.
-
(2010)
PLoS ONE
, vol.5
, pp. e15367
-
-
Globisch, D.1
Munzel, M.2
Muller, M.3
Michalakis, S.4
Wagner, M.5
Koch, S.6
Bruckl, T.7
Biel, M.8
Carell, T.9
-
32
-
-
84869087636
-
The dynamics of DNA methylation in schizophrenia and related psychiatric disorders
-
Grayson D.R., Guidotti A. The dynamics of DNA methylation in schizophrenia and related psychiatric disorders. Neuropsychopharmacology 2013, 38:138-166.
-
(2013)
Neuropsychopharmacology
, vol.38
, pp. 138-166
-
-
Grayson, D.R.1
Guidotti, A.2
-
33
-
-
80053348585
-
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
-
Gu T.P., Guo F., Yang H., Wu H.P., Xu G.F., Liu W., Xie Z.G., Shi L., He X., Jin S.G., Iqbal K., Shi Y.G., Deng Z., Szabo P.E., Pfeifer G.P., Li J., Xu G.L. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 2011, 477:606-610.
-
(2011)
Nature
, vol.477
, pp. 606-610
-
-
Gu, T.P.1
Guo, F.2
Yang, H.3
Wu, H.P.4
Xu, G.F.5
Liu, W.6
Xie, Z.G.7
Shi, L.8
He, X.9
Jin, S.G.10
Iqbal, K.11
Shi, Y.G.12
Deng, Z.13
Szabo, P.E.14
Pfeifer, G.P.15
Li, J.16
Xu, G.L.17
-
34
-
-
33847266846
-
Reversal of neurological defects in a mouse model of Rett syndrome
-
Guy J., Gan J., Selfridge J., Cobb S., Bird A. Reversal of neurological defects in a mouse model of Rett syndrome. Science 2007, 315:1143-1147.
-
(2007)
Science
, vol.315
, pp. 1143-1147
-
-
Guy, J.1
Gan, J.2
Selfridge, J.3
Cobb, S.4
Bird, A.5
-
35
-
-
0035838379
-
Intention tremor, parkinsonism, and generalized brain atrophy in male carriers of fragile X
-
Hagerman R.J., Leehey M., Heinrichs W., Tassone F., Wilson R., Hills J., Grigsby J., Gage B., Hagerman P.J. Intention tremor, parkinsonism, and generalized brain atrophy in male carriers of fragile X. Neurology 2001, 57:127-130.
-
(2001)
Neurology
, vol.57
, pp. 127-130
-
-
Hagerman, R.J.1
Leehey, M.2
Heinrichs, W.3
Tassone, F.4
Wilson, R.5
Hills, J.6
Grigsby, J.7
Gage, B.8
Hagerman, P.J.9
-
36
-
-
2342453253
-
Fragile-X-associated tremor/ataxia syndrome (FXTAS) in females with the FMR1 premutation
-
Hagerman R.J., Leavitt B.R., Farzin F., Jacquemont S., Greco C.M., Brunberg J.A., Tassone F., Hessl D., Harris S.W., Zhang L., Jardini T., Gane L.W., Ferranti J., Ruiz L., Leehey M.A., Grigsby J., Hagerman P.J. Fragile-X-associated tremor/ataxia syndrome (FXTAS) in females with the FMR1 premutation. Am. J. Hum. Genet. 2004, 74:1051-1056.
-
(2004)
Am. J. Hum. Genet.
, vol.74
, pp. 1051-1056
-
-
Hagerman, R.J.1
Leavitt, B.R.2
Farzin, F.3
Jacquemont, S.4
Greco, C.M.5
Brunberg, J.A.6
Tassone, F.7
Hessl, D.8
Harris, S.W.9
Zhang, L.10
Jardini, T.11
Gane, L.W.12
Ferranti, J.13
Ruiz, L.14
Leehey, M.A.15
Grigsby, J.16
Hagerman, P.J.17
-
37
-
-
67249150481
-
Ectopic expression of CGG containing mRNA is neurotoxic in mammals
-
Hashem V., Galloway J.N., Mori M., Willemsen R., Oostra B.A., Paylor R., Nelson D.L. Ectopic expression of CGG containing mRNA is neurotoxic in mammals. Hum. Mol. Genet. 2009, 18:2443-2451.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 2443-2451
-
-
Hashem, V.1
Galloway, J.N.2
Mori, M.3
Willemsen, R.4
Oostra, B.A.5
Paylor, R.6
Nelson, D.L.7
-
38
-
-
84860221291
-
Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation
-
Hashimoto H., Liu Y., Upadhyay A.K., Chang Y., Howerton S.B., Vertino P.M., Zhang X., Cheng X. Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation. Nucleic Acids Res. 2012, 40:4841-4849.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 4841-4849
-
-
Hashimoto, H.1
Liu, Y.2
Upadhyay, A.K.3
Chang, Y.4
Howerton, S.B.5
Vertino, P.M.6
Zhang, X.7
Cheng, X.8
-
39
-
-
36348930605
-
The role of brain-derived neurotrophic factor (BDNF)-induced XBP1 splicing during brain development
-
Hayashi A., Kasahara T., Iwamoto K., Ishiwata M., Kametani M., Kakiuchi C., Furuichi T., Kato T. The role of brain-derived neurotrophic factor (BDNF)-induced XBP1 splicing during brain development. J. Biol. Chem. 2007, 282:34525-34534.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 34525-34534
-
-
Hayashi, A.1
Kasahara, T.2
Iwamoto, K.3
Ishiwata, M.4
Kametani, M.5
Kakiuchi, C.6
Furuichi, T.7
Kato, T.8
-
40
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He Y.F., Li B.Z., Li Z., Liu P., Wang Y., Tang Q., Ding J., Jia Y., Chen Z., Li L., Sun Y., Li X., Dai Q., Song C.X., Zhang K., He C., Xu G.L. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 2011, 333:1303-1307.
-
(2011)
Science
, vol.333
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
Liu, P.4
Wang, Y.5
Tang, Q.6
Ding, J.7
Jia, Y.8
Chen, Z.9
Li, L.10
Sun, Y.11
Li, X.12
Dai, Q.13
Song, C.X.14
Zhang, K.15
He, C.16
Xu, G.L.17
-
41
-
-
0031792779
-
Identification and characterization of a family of mammalian methyl-CpG binding proteins
-
Hendrich B., Bird A. Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol. Cell. Biol. 1998, 18:6538-6547.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6538-6547
-
-
Hendrich, B.1
Bird, A.2
-
42
-
-
77952678006
-
Epigenetic control of neural precursor cell fate during development. Nature reviews
-
Hirabayashi Y., Gotoh Y. Epigenetic control of neural precursor cell fate during development. Nature reviews. Neuroscience 2010, 11:377-388.
-
(2010)
Neuroscience
, vol.11
, pp. 377-388
-
-
Hirabayashi, Y.1
Gotoh, Y.2
-
43
-
-
84864457997
-
Dynamics of DNA methylation in aging and Alzheimer's disease
-
Irier H.A., Jin P. Dynamics of DNA methylation in aging and Alzheimer's disease. DNA Cell Biol. 2012, 31(Suppl. 1):S42-S48.
-
(2012)
DNA Cell Biol.
, vol.31
, pp. S42-S48
-
-
Irier, H.A.1
Jin, P.2
-
44
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
Ito S., D'Alessio A.C., Taranova O.V., Hong K., Sowers L.C., Zhang Y. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 2010, 466:1129-1133.
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
D'Alessio, A.C.2
Taranova, O.V.3
Hong, K.4
Sowers, L.C.5
Zhang, Y.6
-
45
-
-
80052461558
-
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
-
Ito S., Shen L., Dai Q., Wu S.C., Collins L.B., Swenberg J.A., He C., Zhang Y. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 2011, 333:1300-1303.
-
(2011)
Science
, vol.333
, pp. 1300-1303
-
-
Ito, S.1
Shen, L.2
Dai, Q.3
Wu, S.C.4
Collins, L.B.5
Swenberg, J.A.6
He, C.7
Zhang, Y.8
-
46
-
-
66749152204
-
Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids
-
Iyer L.M., Tahiliani M., Rao A., Aravind L. Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids. Cell Cycle 2009, 8:1698-1710.
-
(2009)
Cell Cycle
, vol.8
, pp. 1698-1710
-
-
Iyer, L.M.1
Tahiliani, M.2
Rao, A.3
Aravind, L.4
-
48
-
-
9144252520
-
Penetrance of the fragile X-associated tremor/ataxia syndrome in a premutation carrier population
-
Jacquemont S., Hagerman R.J., Leehey M.A., Hall D.A., Levine R.A., Brunberg J.A., Zhang L., Jardini T., Gane L.W., Harris S.W., Herman K., Grigsby J., Greco C.M., Berry-Kravis E., Tassone F., Hagerman P.J. Penetrance of the fragile X-associated tremor/ataxia syndrome in a premutation carrier population. JAMA 2004, 291:460-469.
-
(2004)
JAMA
, vol.291
, pp. 460-469
-
-
Jacquemont, S.1
Hagerman, R.J.2
Leehey, M.A.3
Hall, D.A.4
Levine, R.A.5
Brunberg, J.A.6
Zhang, L.7
Jardini, T.8
Gane, L.W.9
Harris, S.W.10
Herman, K.11
Grigsby, J.12
Greco, C.M.13
Berry-Kravis, E.14
Tassone, F.15
Hagerman, P.J.16
-
49
-
-
70350046301
-
Rethinking how DNA methylation patterns are maintained. Nature reviews
-
Jones P.A., Liang G. Rethinking how DNA methylation patterns are maintained. Nature reviews. Genetics 2009, 10:805-811.
-
(2009)
Genetics
, vol.10
, pp. 805-811
-
-
Jones, P.A.1
Liang, G.2
-
50
-
-
54949144402
-
The autistic neuron: troubled translation?
-
Kelleher R.J., Bear M.F. The autistic neuron: troubled translation?. Cell 2008, 135:401-406.
-
(2008)
Cell
, vol.135
, pp. 401-406
-
-
Kelleher, R.J.1
Bear, M.F.2
-
51
-
-
84867230056
-
5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary
-
Khare T., Pai S., Koncevicius K., Pal M., Kriukiene E., Liutkeviciute Z., Irimia M., Jia P., Ptak C., Xia M., Tice R., Tochigi M., Morera S., Nazarians A., Belsham D., Wong A.H., Blencowe B.J., Wang S.C., Kapranov P., Kustra R., Labrie V., Klimasauskas S., Petronis A. 5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary. Nat. Struct. Mol. Biol. 2012, 19:1037-1043.
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 1037-1043
-
-
Khare, T.1
Pai, S.2
Koncevicius, K.3
Pal, M.4
Kriukiene, E.5
Liutkeviciute, Z.6
Irimia, M.7
Jia, P.8
Ptak, C.9
Xia, M.10
Tice, R.11
Tochigi, M.12
Morera, S.13
Nazarians, A.14
Belsham, D.15
Wong, A.H.16
Blencowe, B.J.17
Wang, S.C.18
Kapranov, P.19
Kustra, R.20
Labrie, V.21
Klimasauskas, S.22
Petronis, A.23
more..
-
52
-
-
84892449532
-
Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineage
-
Kim M., Park Y.-K., Kang T.-W., Lee S.-H., Rhee Y.-H., Park J.-L., Kim H.-J., Lee D., Lee D., Kim S.-Y., Kim Y.S. Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineage. Hum. Mol. Genet. 2014, 23:657-667.
-
(2014)
Hum. Mol. Genet.
, vol.23
, pp. 657-667
-
-
Kim, M.1
Park, Y.-K.2
Kang, T.-W.3
Lee, S.-H.4
Rhee, Y.-H.5
Park, J.-L.6
Kim, H.-J.7
Lee, D.8
Lee, D.9
Kim, S.-Y.10
Kim, Y.S.11
-
53
-
-
84877582944
-
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX
-
Ko M., An J., Bandukwala H.S., Chavez L., Aijo T., Pastor W.A., Segal M.F., Li H., Koh K.P., Lahdesmaki H., Hogan P.G., Aravind L., Rao A. Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX. Nature 2013, 497:122-126.
-
(2013)
Nature
, vol.497
, pp. 122-126
-
-
Ko, M.1
An, J.2
Bandukwala, H.S.3
Chavez, L.4
Aijo, T.5
Pastor, W.A.6
Segal, M.F.7
Li, H.8
Koh, K.P.9
Lahdesmaki, H.10
Hogan, P.G.11
Aravind, L.12
Rao, A.13
-
54
-
-
70149094108
-
Neurocognitive profile in children with fetal alcohol spectrum disorders
-
Kodituwakku P.W. Neurocognitive profile in children with fetal alcohol spectrum disorders. Dev. Disabil. Res. Rev. 2009, 15:218-224.
-
(2009)
Dev. Disabil. Res. Rev.
, vol.15
, pp. 218-224
-
-
Kodituwakku, P.W.1
-
55
-
-
79551587102
-
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells
-
Koh K.P., Yabuuchi A., Rao S., Huang Y., Cunniff K., Nardone J., Laiho A., Tahiliani M., Sommer C.A., Mostoslavsky G., Lahesmaa R., Orkin S.H., Rodig S.J., Daley G.Q., Rao A. Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell 2011, 8:200-213.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 200-213
-
-
Koh, K.P.1
Yabuuchi, A.2
Rao, S.3
Huang, Y.4
Cunniff, K.5
Nardone, J.6
Laiho, A.7
Tahiliani, M.8
Sommer, C.A.9
Mostoslavsky, G.10
Lahesmaa, R.11
Orkin, S.H.12
Rodig, S.J.13
Daley, G.Q.14
Rao, A.15
-
56
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis S., Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 2009, 324:929-930.
-
(2009)
Science
, vol.324
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
57
-
-
84865159829
-
Epigenetics of major psychosis: progress, problems and perspectives
-
Labrie V., Pai S., Petronis A. Epigenetics of major psychosis: progress, problems and perspectives. Trends Genet. 2012, 28:427-435.
-
(2012)
Trends Genet.
, vol.28
, pp. 427-435
-
-
Labrie, V.1
Pai, S.2
Petronis, A.3
-
58
-
-
0036308284
-
Schizophrenia as a disorder of neurodevelopment
-
Lewis D.A., Levitt P. Schizophrenia as a disorder of neurodevelopment. Annu. Rev. Neurosci. 2002, 25:409-432.
-
(2002)
Annu. Rev. Neurosci.
, vol.25
, pp. 409-432
-
-
Lewis, D.A.1
Levitt, P.2
-
59
-
-
0026747761
-
Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA
-
Lewis J.D., Meehan R.R., Henzel W.J., Maurer-Fogy I., Jeppesen P., Klein F., Bird A. Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA. Cell 1992, 69:905-914.
-
(1992)
Cell
, vol.69
, pp. 905-914
-
-
Lewis, J.D.1
Meehan, R.R.2
Henzel, W.J.3
Maurer-Fogy, I.4
Jeppesen, P.5
Klein, F.6
Bird, A.7
-
60
-
-
0036733675
-
Chromatin modification and epigenetic reprogramming in mammalian development. Nature reviews
-
Li E. Chromatin modification and epigenetic reprogramming in mammalian development. Nature reviews. Genetics 2002, 3:662-673.
-
(2002)
Genetics
, vol.3
, pp. 662-673
-
-
Li, E.1
-
61
-
-
57449099863
-
Epigenetic regulation of mammalian stem cells
-
Li X., Zhao X. Epigenetic regulation of mammalian stem cells. Stem Cells Dev. 2008, 17:1043-1052.
-
(2008)
Stem Cells Dev.
, vol.17
, pp. 1043-1052
-
-
Li, X.1
Zhao, X.2
-
62
-
-
79960907896
-
A role for glia in the progression of Rett's syndrome
-
Lioy D.T., Garg S.K., Monaghan C.E., Raber J., Foust K.D., Kaspar B.K., Hirrlinger P.G., Kirchhoff F., Bissonnette J.M., Ballas N., Mandel G. A role for glia in the progression of Rett's syndrome. Nature 2011, 475:497-500.
-
(2011)
Nature
, vol.475
, pp. 497-500
-
-
Lioy, D.T.1
Garg, S.K.2
Monaghan, C.E.3
Raber, J.4
Foust, K.D.5
Kaspar, B.K.6
Hirrlinger, P.G.7
Kirchhoff, F.8
Bissonnette, J.M.9
Ballas, N.10
Mandel, G.11
-
63
-
-
77958605856
-
Epigenetic choreographers of neurogenesis in the adult mammalian brain
-
Ma D.K., Marchetto M.C., Guo J.U., Ming G.L., Gage F.H., Song H. Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nat. Neurosci. 2010, 13:1338-1344.
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 1338-1344
-
-
Ma, D.K.1
Marchetto, M.C.2
Guo, J.U.3
Ming, G.L.4
Gage, F.H.5
Song, H.6
-
64
-
-
80053917872
-
Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites
-
Maiti A., Drohat A.C. Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites. J. Biol. Chem. 2011, 286:35334-35338.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 35334-35338
-
-
Maiti, A.1
Drohat, A.C.2
-
65
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini L., Sathasivam K., Seller M., Cozens B., Harper A., Hetherington C., Lawton M., Trottier Y., Lehrach H., Davies S.W., Bates G.P. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 1996, 87:493-506.
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
Bates, G.P.11
-
66
-
-
78650179659
-
Epigenetic changes in Alzheimer's disease: decrements in DNA methylation
-
Mastroeni D., Grover A., Delvaux E., Whiteside C., Coleman P.D., Rogers J. Epigenetic changes in Alzheimer's disease: decrements in DNA methylation. Neurobiol. Aging 2010, 31:2025-2037.
-
(2010)
Neurobiol. Aging
, vol.31
, pp. 2025-2037
-
-
Mastroeni, D.1
Grover, A.2
Delvaux, E.3
Whiteside, C.4
Coleman, P.D.5
Rogers, J.6
-
67
-
-
0035755084
-
Estimating the prevalence of fetal alcohol syndrome. A summary
-
May P.A., Gossage J.P. Estimating the prevalence of fetal alcohol syndrome. A summary. Alcohol Res. Health 2001, 25:159-167.
-
(2001)
Alcohol Res. Health
, vol.25
, pp. 159-167
-
-
May, P.A.1
Gossage, J.P.2
-
68
-
-
84871563384
-
MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
-
Mellen M., Ayata P., Dewell S., Kriaucionis S., Heintz N. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell 2012, 151:1417-1430.
-
(2012)
Cell
, vol.151
, pp. 1417-1430
-
-
Mellen, M.1
Ayata, P.2
Dewell, S.3
Kriaucionis, S.4
Heintz, N.5
-
69
-
-
79960064353
-
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
-
Moran-Crusio K., Reavie L., Shih A., Abdel-Wahab O., Ndiaye-Lobry D., Lobry C., Figueroa M.E., Vasanthakumar A., Patel J., Zhao X., Perna F., Pandey S., Madzo J., Song C., Dai Q., He C., Ibrahim S., Beran M., Zavadil J., Nimer S.D., Melnick A., Godley L.A., Aifantis I., Levine R.L. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell 2011, 20:11-24.
-
(2011)
Cancer Cell
, vol.20
, pp. 11-24
-
-
Moran-Crusio, K.1
Reavie, L.2
Shih, A.3
Abdel-Wahab, O.4
Ndiaye-Lobry, D.5
Lobry, C.6
Figueroa, M.E.7
Vasanthakumar, A.8
Patel, J.9
Zhao, X.10
Perna, F.11
Pandey, S.12
Madzo, J.13
Song, C.14
Dai, Q.15
He, C.16
Ibrahim, S.17
Beran, M.18
Zavadil, J.19
Nimer, S.D.20
Melnick, A.21
Godley, L.A.22
Aifantis, I.23
Levine, R.L.24
more..
-
70
-
-
84857891830
-
Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes
-
Nestor C.E., Ottaviano R., Reddington J., Sproul D., Reinhardt D., Dunican D., Katz E., Dixon J.M., Harrison D.J., Meehan R.R. Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes. Genome Res. 2012, 22:467-477.
-
(2012)
Genome Res.
, vol.22
, pp. 467-477
-
-
Nestor, C.E.1
Ottaviano, R.2
Reddington, J.3
Sproul, D.4
Reinhardt, D.5
Dunican, D.6
Katz, E.7
Dixon, J.M.8
Harrison, D.J.9
Meehan, R.R.10
-
71
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M., Bell D.W., Haber D.A., Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999, 99:247-257.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
72
-
-
79956308473
-
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
-
Pastor W.A., Pape U.J., Huang Y., Henderson H.R., Lister R., Ko M., McLoughlin E.M., Brudno Y., Mahapatra S., Kapranov P., Tahiliani M., Daley G.Q., Liu X.S., Ecker J.R., Milos P.M., Agarwal S., Rao A. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature 2011, 473:394-397.
-
(2011)
Nature
, vol.473
, pp. 394-397
-
-
Pastor, W.A.1
Pape, U.J.2
Huang, Y.3
Henderson, H.R.4
Lister, R.5
Ko, M.6
McLoughlin, E.M.7
Brudno, Y.8
Mahapatra, S.9
Kapranov, P.10
Tahiliani, M.11
Daley, G.Q.12
Liu, X.S.13
Ecker, J.R.14
Milos, P.M.15
Agarwal, S.16
Rao, A.17
-
73
-
-
84878260646
-
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription. Nature reviews
-
Pastor W.A., Aravind L., Rao A. TETonic shift: biological roles of TET proteins in DNA demethylation and transcription. Nature reviews. Mol. Cell. Biol. 2013, 14:341-356.
-
(2013)
Mol. Cell. Biol.
, vol.14
, pp. 341-356
-
-
Pastor, W.A.1
Aravind, L.2
Rao, A.3
-
74
-
-
0015298215
-
The presence of 5-hydroxymethylcytosine in animal deoxyribonucleic acid
-
Penn N.W., Suwalski R., O'Riley C., Bojanowski K., Yura R. The presence of 5-hydroxymethylcytosine in animal deoxyribonucleic acid. Biochem. J. 1972, 126:781-790.
-
(1972)
Biochem. J.
, vol.126
, pp. 781-790
-
-
Penn, N.W.1
Suwalski, R.2
O'Riley, C.3
Bojanowski, K.4
Yura, R.5
-
75
-
-
57649196594
-
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45
-
Rai K., Huggins I.J., James S.R., Karpf A.R., Jones D.A., Cairns B.R. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell 2008, 135:1201-1212.
-
(2008)
Cell
, vol.135
, pp. 1201-1212
-
-
Rai, K.1
Huggins, I.J.2
James, S.R.3
Karpf, A.R.4
Jones, D.A.5
Cairns, B.R.6
-
76
-
-
52949138731
-
Autism: definition, neurobiology, screening, diagnosis
-
(viii)
-
Rapin I., Tuchman R.F. Autism: definition, neurobiology, screening, diagnosis. Pediatr. Clin. N. Am. 2008, 55:1129-1146. (viii).
-
(2008)
Pediatr. Clin. N. Am.
, vol.55
, pp. 1129-1146
-
-
Rapin, I.1
Tuchman, R.F.2
-
77
-
-
84874036221
-
Epigenetic medicine and fetal alcohol spectrum disorders
-
Resendiz M., Chen Y., Ozturk N.C., Zhou F.C. Epigenetic medicine and fetal alcohol spectrum disorders. Epigenomics 2013, 5:73-86.
-
(2013)
Epigenomics
, vol.5
, pp. 73-86
-
-
Resendiz, M.1
Chen, Y.2
Ozturk, N.C.3
Zhou, F.C.4
-
78
-
-
59849090498
-
TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation
-
Schmitz K.M., Schmitt N., Hoffmann-Rohrer U., Schafer A., Grummt I., Mayer C. TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation. Mol. Cell 2009, 33:344-353.
-
(2009)
Mol. Cell
, vol.33
, pp. 344-353
-
-
Schmitz, K.M.1
Schmitt, N.2
Hoffmann-Rohrer, U.3
Schafer, A.4
Grummt, I.5
Mayer, C.6
-
79
-
-
36849072573
-
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
-
Sharif J., Muto M., Takebayashi S., Suetake I., Iwamatsu A., Endo T.A., Shinga J., Mizutani-Koseki Y., Toyoda T., Okamura K., Tajima S., Mitsuya K., Okano M., Koseki H. The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature 2007, 450:908-912.
-
(2007)
Nature
, vol.450
, pp. 908-912
-
-
Sharif, J.1
Muto, M.2
Takebayashi, S.3
Suetake, I.4
Iwamatsu, A.5
Endo, T.A.6
Shinga, J.7
Mizutani-Koseki, Y.8
Toyoda, T.9
Okamura, K.10
Tajima, S.11
Mitsuya, K.12
Okano, M.13
Koseki, H.14
-
80
-
-
84874194072
-
DNA methylation: roles in mammalian development. Nature reviews
-
Smith Z.D., Meissner A. DNA methylation: roles in mammalian development. Nature reviews. Genetics 2013, 14:204-220.
-
(2013)
Genetics
, vol.14
, pp. 204-220
-
-
Smith, Z.D.1
Meissner, A.2
-
81
-
-
78651280460
-
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine
-
Song C.X., Szulwach K.E., Fu Y., Dai Q., Yi C., Li X., Li Y., Chen C.H., Zhang W., Jian X., Wang J., Zhang L., Looney T.J., Zhang B., Godley L.A., Hicks L.M., Lahn B.T., Jin P., He C. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat. Biotechnol. 2011, 29:68-72.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 68-72
-
-
Song, C.X.1
Szulwach, K.E.2
Fu, Y.3
Dai, Q.4
Yi, C.5
Li, X.6
Li, Y.7
Chen, C.H.8
Zhang, W.9
Jian, X.10
Wang, J.11
Zhang, L.12
Looney, T.J.13
Zhang, B.14
Godley, L.A.15
Hicks, L.M.16
Lahn, B.T.17
Jin, P.18
He, C.19
-
82
-
-
84874771985
-
Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives
-
Spruijt C.G., Gnerlich F., Smits A.H., Pfaffeneder T., Jansen P.W., Bauer C., Munzel M., Wagner M., Muller M., Khan F., Eberl H.C., Mensinga A., Brinkman A.B., Lephikov K., Muller U., Walter J., Boelens R., van Ingen H., Leonhardt H., Carell T., Vermeulen M. Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives. Cell 2013, 152:1146-1159.
-
(2013)
Cell
, vol.152
, pp. 1146-1159
-
-
Spruijt, C.G.1
Gnerlich, F.2
Smits, A.H.3
Pfaffeneder, T.4
Jansen, P.W.5
Bauer, C.6
Munzel, M.7
Wagner, M.8
Muller, M.9
Khan, F.10
Eberl, H.C.11
Mensinga, A.12
Brinkman, A.B.13
Lephikov, K.14
Muller, U.15
Walter, J.16
Boelens, R.17
van Ingen, H.18
Leonhardt, H.19
Carell, T.20
Vermeulen, M.21
more..
-
83
-
-
82255192294
-
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging
-
Szulwach K.E., Li X., Li Y., Song C.X., Wu H., Dai Q., Irier H., Upadhyay A.K., Gearing M., Levey A.I., Vasanthakumar A., Godley L.A., Chang Q., Cheng X., He C., Jin P. 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat. Neurosci. 2011, 14:1607-1616.
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 1607-1616
-
-
Szulwach, K.E.1
Li, X.2
Li, Y.3
Song, C.X.4
Wu, H.5
Dai, Q.6
Irier, H.7
Upadhyay, A.K.8
Gearing, M.9
Levey, A.I.10
Vasanthakumar, A.11
Godley, L.A.12
Chang, Q.13
Cheng, X.14
He, C.15
Jin, P.16
-
84
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M., Koh K.P., Shen Y., Pastor W.A., Bandukwala H., Brudno Y., Agarwal S., Iyer L.M., Liu D.R., Aravind L., Rao A. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 2009, 324:930-935.
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
Agarwal, S.7
Iyer, L.M.8
Liu, D.R.9
Aravind, L.10
Rao, A.11
-
85
-
-
0034571171
-
Huntington's disease: the challenge for cell biologists
-
Tobin A.J., Signer E.R. Huntington's disease: the challenge for cell biologists. Trends Cell Biol. 2000, 10:531-536.
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 531-536
-
-
Tobin, A.J.1
Signer, E.R.2
-
86
-
-
68949180394
-
Schizophrenia
-
van Os J., Kapur S. Schizophrenia. Lancet 2009, 374:635-645.
-
(2009)
Lancet
, vol.374
, pp. 635-645
-
-
van Os, J.1
Kapur, S.2
-
87
-
-
84877744385
-
Increased 5-methylcytosine and decreased 5-hydroxymethylcytosine levels are associated with reduced striatal A2AR levels in Huntington's disease
-
Villar-Menendez I., Blanch M., Tyebji S., Pereira-Veiga T., Albasanz J.L., Martin M., Ferrer I., Perez-Navarro E., Barrachina M. Increased 5-methylcytosine and decreased 5-hydroxymethylcytosine levels are associated with reduced striatal A2AR levels in Huntington's disease. Neruomol. Med. 2013, 15:295-309.
-
(2013)
Neruomol. Med.
, vol.15
, pp. 295-309
-
-
Villar-Menendez, I.1
Blanch, M.2
Tyebji, S.3
Pereira-Veiga, T.4
Albasanz, J.L.5
Martin, M.6
Ferrer, I.7
Perez-Navarro, E.8
Barrachina, M.9
-
89
-
-
33846225133
-
Huntington's disease
-
Walker F.O. Huntington's disease. Lancet 2007, 369:218-228.
-
(2007)
Lancet
, vol.369
, pp. 218-228
-
-
Walker, F.O.1
-
90
-
-
84870856116
-
Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum
-
Wang T., Pan Q., Lin L., Szulwach K.E., Song C.X., He C., Wu H., Warren S.T., Jin P., Duan R., Li X. Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum. Hum. Mol. Genet. 2012, 21:5500-5510.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 5500-5510
-
-
Wang, T.1
Pan, Q.2
Lin, L.3
Szulwach, K.E.4
Song, C.X.5
He, C.6
Wu, H.7
Warren, S.T.8
Jin, P.9
Duan, R.10
Li, X.11
-
91
-
-
84883012277
-
Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease
-
Wang F., Yang Y., Lin X., Wang J.Q., Wu Y.S., Xie W., Wang D., Zhu S., Liao Y.Q., Sun Q., Yang Y.G., Luo H.R., Guo C., Han C., Tang T.S. Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease. Hum. Mol. Genet. 2013, 22:3641-3653.
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 3641-3653
-
-
Wang, F.1
Yang, Y.2
Lin, X.3
Wang, J.Q.4
Wu, Y.S.5
Xie, W.6
Wang, D.7
Zhu, S.8
Liao, Y.Q.9
Sun, Q.10
Yang, Y.G.11
Luo, H.R.12
Guo, C.13
Han, C.14
Tang, T.S.15
-
92
-
-
0042508791
-
Neuropathologic changes in Alzheimer's disease
-
Wenk G.L. Neuropathologic changes in Alzheimer's disease. J. Clin. Psychiatry 2003, 64(Suppl. 9):7-10.
-
(2003)
J. Clin. Psychiatry
, vol.64
, pp. 7-10
-
-
Wenk, G.L.1
-
93
-
-
13644269956
-
Aryl hydrocarbon receptor expression and activity in cerebellar granule neuroblasts: implications for development and dioxin neurotoxicity
-
Williamson M.A., Gasiewicz T.A., Opanashuk L.A. Aryl hydrocarbon receptor expression and activity in cerebellar granule neuroblasts: implications for development and dioxin neurotoxicity. Toxicol. Sci. 2005, 83:340-348.
-
(2005)
Toxicol. Sci.
, vol.83
, pp. 340-348
-
-
Williamson, M.A.1
Gasiewicz, T.A.2
Opanashuk, L.A.3
-
94
-
-
82955207588
-
Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation
-
Wu H., Zhang Y. Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation. Genes Dev. 2011, 25:2436-2452.
-
(2011)
Genes Dev.
, vol.25
, pp. 2436-2452
-
-
Wu, H.1
Zhang, Y.2
-
95
-
-
79954457998
-
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
-
Wu H., D'Alessio A.C., Ito S., Wang Z., Cui K., Zhao K., Sun Y.E., Zhang Y. Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes Dev. 2011, 25:679-684.
-
(2011)
Genes Dev.
, vol.25
, pp. 679-684
-
-
Wu, H.1
D'Alessio, A.C.2
Ito, S.3
Wang, Z.4
Cui, K.5
Zhao, K.6
Sun, Y.E.7
Zhang, Y.8
-
96
-
-
0001129080
-
The bases of the nucleic acids of some bacterial and animal viruses: the occurrence of 5-hydroxymethylcytosine
-
Wyatt G.R., Cohen S.S. The bases of the nucleic acids of some bacterial and animal viruses: the occurrence of 5-hydroxymethylcytosine. Biochem. J. 1953, 55:774-782.
-
(1953)
Biochem. J.
, vol.55
, pp. 774-782
-
-
Wyatt, G.R.1
Cohen, S.S.2
-
97
-
-
79955948324
-
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells
-
Xu Y., Wu F., Tan L., Kong L., Xiong L., Deng J., Barbera A.J., Zheng L., Zhang H., Huang S., Min J., Nicholson T., Chen T., Xu G., Shi Y., Zhang K., Shi Y.G. Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells. Mol. Cell 2011, 42:451-464.
-
(2011)
Mol. Cell
, vol.42
, pp. 451-464
-
-
Xu, Y.1
Wu, F.2
Tan, L.3
Kong, L.4
Xiong, L.5
Deng, J.6
Barbera, A.J.7
Zheng, L.8
Zhang, H.9
Huang, S.10
Min, J.11
Nicholson, T.12
Chen, T.13
Xu, G.14
Shi, Y.15
Zhang, K.16
Shi, Y.G.17
-
98
-
-
84870883633
-
Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development
-
Xu Y., Xu C., Kato A., Tempel W., Abreu J.G., Bian C., Hu Y., Hu D., Zhao B., Cerovina T., Diao J., Wu F., He H.H., Cui Q., Clark E., Ma C., Barbara A., Veenstra G.J., Xu G., Kaiser U.B., Liu X.S., Sugrue S.P., He X., Min J., Kato Y., Shi Y.G. Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development. Cell 2012, 151:1200-1213.
-
(2012)
Cell
, vol.151
, pp. 1200-1213
-
-
Xu, Y.1
Xu, C.2
Kato, A.3
Tempel, W.4
Abreu, J.G.5
Bian, C.6
Hu, Y.7
Hu, D.8
Zhao, B.9
Cerovina, T.10
Diao, J.11
Wu, F.12
He, H.H.13
Cui, Q.14
Clark, E.15
Ma, C.16
Barbara, A.17
Veenstra, G.J.18
Xu, G.19
Kaiser, U.B.20
Liu, X.S.21
Sugrue, S.P.22
He, X.23
Min, J.24
Kato, Y.25
Shi, Y.G.26
more..
-
99
-
-
84892785746
-
Cytosine modifications in neurodevelopment and diseases
-
Yao B., Jin P. Cytosine modifications in neurodevelopment and diseases. Cell. Mol. Life Sci. 2014, 71:405-418.
-
(2014)
Cell. Mol. Life Sci.
, vol.71
, pp. 405-418
-
-
Yao, B.1
Jin, P.2
-
100
-
-
84893015285
-
Genome-wide alteration of 5-hydroxymethylcytosine in a mouse model of fragile X-associated tremor/ataxia syndrome
-
Yao B., Lin L., Street R.C., Zalewski Z.A., Galloway J.N., Wu H., Nelson D.L., Jin P. Genome-wide alteration of 5-hydroxymethylcytosine in a mouse model of fragile X-associated tremor/ataxia syndrome. Hum. Mol. Genet. 2014, 23:1095-1107.
-
(2014)
Hum. Mol. Genet.
, vol.23
, pp. 1095-1107
-
-
Yao, B.1
Lin, L.2
Street, R.C.3
Zalewski, Z.A.4
Galloway, J.N.5
Wu, H.6
Nelson, D.L.7
Jin, P.8
-
101
-
-
84455167621
-
Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells
-
Yildirim O., Li R., Hung J.H., Chen P.B., Dong X., Ee L.S., Weng Z., Rando O.J., Fazzio T.G. Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells. Cell 2011, 147:1498-1510.
-
(2011)
Cell
, vol.147
, pp. 1498-1510
-
-
Yildirim, O.1
Li, R.2
Hung, J.H.3
Chen, P.B.4
Dong, X.5
Ee, L.S.6
Weng, Z.7
Rando, O.J.8
Fazzio, T.G.9
-
102
-
-
84861990517
-
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome
-
Yu M., Hon G.C., Szulwach K.E., Song C.X., Zhang L., Kim A., Li X., Dai Q., Shen Y., Park B., Min J.H., Jin P., Ren B., He C. Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell 2012, 149:1368-1380.
-
(2012)
Cell
, vol.149
, pp. 1368-1380
-
-
Yu, M.1
Hon, G.C.2
Szulwach, K.E.3
Song, C.X.4
Zhang, L.5
Kim, A.6
Li, X.7
Dai, Q.8
Shen, Y.9
Park, B.10
Min, J.H.11
Jin, P.12
Ren, B.13
He, C.14
-
103
-
-
78649825211
-
TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine
-
Zhang H., Zhang X., Clark E., Mulcahey M., Huang S., Shi Y.G. TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine. Cell Res. 2010, 20:1390-1393.
-
(2010)
Cell Res.
, vol.20
, pp. 1390-1393
-
-
Zhang, H.1
Zhang, X.2
Clark, E.3
Mulcahey, M.4
Huang, S.5
Shi, Y.G.6
-
104
-
-
84892954147
-
Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum
-
Zhubi A., Chen Y., Dong E., Cook E.H., Guidotti A., Grayson D.R. Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum. Transl. Psychiatr. 2014, 4:e349.
-
(2014)
Transl. Psychiatr.
, vol.4
, pp. e349
-
-
Zhubi, A.1
Chen, Y.2
Dong, E.3
Cook, E.H.4
Guidotti, A.5
Grayson, D.R.6
|