The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner

Cell Stem Cell

Volumn 9, Issue 6, 2011, Pages 575-587

  Wang, Tao ^a   Chen, Keshi ^a   Zeng, Xiaoming ^a   Yang, Jianguo ^a   Wu, Yun ^a   Shi, Xi ^a   Qin, Baoming ^a   Zeng, Lingwen ^a   Esteban, Miguel Angel ^a   Pan, Guangjin ^a   Pei, Duanqing ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARF PROTEIN; ASCORBIC ACID; HISTONE DEMETHYLASE; MICRORNA; OCTAMER TRANSCRIPTION FACTOR 4;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CYCLE PROGRESSION; CELL FATE; CONTROLLED STUDY; DEMETHYLATION; EMBRYO; FIBROBLAST; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SENESCENCE; SOMATIC CELL;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; CELL AGING; CELL CYCLE; CELLS, CULTURED; F-BOX PROTEINS; FIBROBLASTS; HISTONES; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; LYSINE; MICE; MICE, TRANSGENIC; NUCLEAR REPROGRAMMING; OCTAMER TRANSCRIPTION FACTOR-3; PLURIPOTENT STEM CELLS;

EID: 82755187396     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2011.10.005     Document Type: Article

References (52)

1. A. Adamo, B. Sesé, S. Boue, J. Castaño, I. Paramonov, M.J. Barrero, and J.C. Izpisua Belmonte LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells Nat. Cell Biol. 13 2011 652 659
2. Y.S. Ang, S.Y. Tsai, D.F. Lee, J. Monk, J. Su, K. Ratnakumar, J. Ding, Y. Ge, H. Darr, and B. Chang Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network Cell 145 2011 183 197
3. F. Anokye-Danso, C.M. Trivedi, D. Juhr, M. Gupta, Z. Cui, Y. Tian, Y. Zhang, W. Yang, P.J. Gruber, J.A. Epstein, and E.E. Morrisey Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency Cell Stem Cell 8 2011 376 388
4. A. Barroso-delJesus, C. Romero-López, G. Lucena-Aguilar, G.J. Melen, L. Sanchez, G. Ligero, A. Berzal-Herranz, and P. Menendez Embryonic stem cell-specific miR302-367 cluster: human gene structure and functional characterization of its core promoter Mol. Cell. Biol. 28 2008 6609 6619
5. B.E. Bernstein, T.S. Mikkelsen, X. Xie, M. Kamal, D.J. Huebert, J. Cuff, B. Fry, A. Meissner, M. Wernig, and K. Plath A bivalent chromatin structure marks key developmental genes in embryonic stem cells Cell 125 2006 315 326
6. N.P. Blackledge, J.C. Zhou, M.Y. Tolstorukov, A.M. Farcas, P.J. Park, and R.J. Klose CpG islands recruit a histone H3 lysine 36 demethylase Mol. Cell 38 2010 179 190
7. J. Chen, J. Liu, Q. Han, D. Qin, J. Xu, Y. Chen, J. Yang, H. Song, D. Yang, and M. Peng Towards an optimized culture medium for the generation of mouse induced pluripotent stem cells J. Biol. Chem. 285 2010 31066 31072
8. J. Chen, J. Liu, J. Yang, Y. Chen, J. Chen, S. Ni, H. Song, L. Zeng, K. Ding, and D. Pei BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone Cell Res. 21 2011 205 212
9. T.L. Chung, R.M. Brena, G. Kolle, S.M. Grimmond, B.P. Berman, P.W. Laird, M.F. Pera, and E.J. Wolvetang Vitamin C promotes widespread yet specific DNA demethylation of the epigenome in human embryonic stem cells Stem Cells 28 2010 1848 1855
10. M.A. Esteban, T. Wang, B. Qin, J. Yang, D. Qin, J. Cai, W. Li, Z. Weng, J. Chen, and S. Ni Vitamin C enhances the generation of mouse and human induced pluripotent stem cells Cell Stem Cell 6 2010 71 79
11. J. Hanna, K. Saha, B. Pando, J. van Zon, C.J. Lengner, M.P. Creyghton, A. van Oudenaarden, and R. Jaenisch Direct cell reprogramming is a stochastic process amenable to acceleration Nature 462 2009 595 601
12. J. He, E.M. Kallin, Y. Tsukada, and Y. Zhang The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15(Ink4b) Nat. Struct. Mol. Biol. 15 2008 1169 1175
13. J.R. Horton, A.K. Upadhyay, H.H. Qi, X. Zhang, Y. Shi, and X. Cheng Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases Nat. Struct. Mol. Biol. 17 2010 38 43
14. D. Huangfu, K. Osafune, R. Maehr, W. Guo, A. Eijkelenboom, S. Chen, W. Muhlestein, and D.A. Melton Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2 Nat. Biotechnol. 26 2008 1269 1275
15. L. Kang, J. Wang, Y. Zhang, Z. Kou, and S. Gao iPS cells can support full-term development of tetraploid blastocyst-complemented embryos Cell Stem Cell 5 2009 135 138
16. H.J. Knowles, R.R. Raval, A.L. Harris, and P.J. Ratcliffe Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells Cancer Res. 63 2003 1764 1768 (Pubitemid 36460834)
17. R.P. Koche, Z.D. Smith, M. Adli, H. Gu, M. Ku, A. Gnirke, B.E. Bernstein, and A. Meissner Reprogramming factor expression initiates widespread targeted chromatin remodeling Cell Stem Cell 8 2011 96 105
18. H. Li, M. Collado, A. Villasante, K. Strati, S. Ortega, M. Cañamero, M.A. Blasco, and M. Serrano The Ink4/Arf locus is a barrier for iPS cell reprogramming Nature 460 2009 1136 1139
19. R. Li, J. Liang, S. Ni, T. Zhou, X. Qing, H. Li, W. He, J. Chen, F. Li, and Q. Zhuang A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts Cell Stem Cell 7 2010 51 63
20. Y. Li, Q. Zhang, X. Yin, W. Yang, Y. Du, P. Hou, J. Ge, C. Liu, W. Zhang, and X. Zhang Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules Cell Res. 21 2011 196 204
21. G. Liang, O. Taranova, K. Xia, and Y. Zhang Butyrate promotes induced pluripotent stem cell generation J. Biol. Chem. 285 2010 25516 25521
22. B. Liao, X. Bao, L. Liu, S. Feng, A. Zovoilis, W. Liu, Y. Xue, J. Cai, X. Guo, and B. Qin MicroRNA cluster 302-367 enhances somatic cell reprogramming by accelerating a mesenchymal-to-epithelial transition J. Biol. Chem. 286 2011 17359 17364
23. T. Lin, R. Ambasudhan, X. Yuan, W. Li, S. Hilcove, R. Abujarour, X. Lin, H.S. Hahm, E. Hao, A. Hayek, and S. Ding A chemical platform for improved induction of human iPSCs Nat. Methods 6 2009 805 808
24. R. Lister, M. Pelizzola, R.H. Dowen, R.D. Hawkins, G. Hon, J. Tonti-Filippini, J.R. Nery, L. Lee, Z. Ye, and Q.M. Ngo Human DNA methylomes at base resolution show widespread epigenomic differences Nature 462 2009 315 322
25. D.K. Ma, C.H. Chiang, K. Ponnusamy, G.L. Ming, and H. Song G9a and Jhdm2a regulate embryonic stem cell fusion-induced reprogramming of adult neural stem cells Stem Cells 26 2008 2131 2141
26. N. Maherali, R. Sridharan, W. Xie, J. Utikal, S. Eminli, K. Arnold, M. Stadtfeld, R. Yachechko, J. Tchieu, and R. Jaenisch Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution Cell Stem Cell 1 2007 55 70
27. P. Mali, B.K. Chou, J. Yen, Z. Ye, J. Zou, S. Dowey, R.A. Brodsky, J.E. Ohm, W. Yu, and S.B. Baylin Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes Stem Cells 28 2010 713 720
28. T.S. Mikkelsen, J. Hanna, X. Zhang, M. Ku, M. Wernig, P. Schorderet, B.E. Bernstein, R. Jaenisch, E.S. Lander, and A. Meissner Dissecting direct reprogramming through integrative genomic analysis Nature 454 2008 49 55 (Pubitemid 351931978)
29. N. Miyoshi, H. Ishii, H. Nagano, N. Haraguchi, D.L. Dewi, Y. Kano, S. Nishikawa, M. Tanemura, K. Mimori, and F. Tanaka Reprogramming of mouse and human cells to pluripotency using mature microRNAs Cell Stem Cell 8 2011 633 638
30. J.D. Nelson, O. Denisenko, P. Sova, and K. Bomsztyk Fast chromatin immunoprecipitation assay Nucleic Acids Res. 34 2006 e2
31. M. Pawlak, and R. Jaenisch De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state Genes Dev. 25 2011 1035 1040
32. B. Peterkofsky Ascorbate requirement for hydroxylation and secretion of procollagen: relationship to inhibition of collagen synthesis in scurvy Am. J. Clin. Nutr. 54 6, Suppl 1991 1135S 1140S
33. K. Plath, and W.E. Lowry Progress in understanding reprogramming to the induced pluripotent state Nat. Rev. Genet. 12 2011 253 265
34. P. Samavarchi-Tehrani, A. Golipour, L. David, H.K. Sung, T.A. Beyer, A. Datti, K. Woltjen, A. Nagy, and J.L. Wrana Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming Cell Stem Cell 7 2010 64 77
35. D. Shechter, H.L. Dormann, C.D. Allis, and S.B. Hake Extraction, purification and analysis of histones Nat. Protoc. 2 2007 1445 1457 (Pubitemid 46952324)
36. N. Singhal, J. Graumann, G. Wu, M.J. Araúzo-Bravo, D.W. Han, B. Greber, L. Gentile, M. Mann, and H.R. Schöler Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming Cell 141 2010 943 955
37. R. Sridharan, J. Tchieu, M.J. Mason, R. Yachechko, E. Kuoy, S. Horvath, Q. Zhou, and K. Plath Role of the murine reprogramming factors in the induction of pluripotency Cell 136 2009 364 377
38. M. Stadtfeld, N. Maherali, D.T. Breault, and K. Hochedlinger Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse Cell Stem Cell 2 2008 230 240
39. D. Subramanyam, S. Lamouille, R.L. Judson, J.Y. Liu, N. Bucay, R. Derynck, and R. Blelloch Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells Nat. Biotechnol. 29 2011 443 448
40. K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 2006 663 676 (Pubitemid 44233629)
41. K. Takahashi, K. Tanabe, M. Ohnuki, M. Narita, T. Ichisaka, K. Tomoda, and S. Yamanaka Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 2007 861 872 (Pubitemid 350138099)
42. M.G. Traber, and J.F. Stevens Vitamins C and E: beneficial effects from a mechanistic perspective Free Radic. Biol. Med. 51 2011 1000 1013
43. A. Tzatsos, R. Pfau, S.C. Kampranis, and P.N. Tsichlis Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus Proc. Natl. Acad. Sci. USA 106 2009 2641 2646
44. W.B. Van Robertson, and B. Schwartz Ascorbic acid and the formation of collagen J. Biol. Chem. 201 1953 689 696
45. Y. Wang, S. Baskerville, A. Shenoy, J.E. Babiarz, L. Baehner, and R. Blelloch Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation Nat. Genet. 40 2008 1478 1483
46. M. Wernig, A. Meissner, R. Foreman, T. Brambrink, M. Ku, K. Hochedlinger, B.E. Bernstein, and R. Jaenisch In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state Nature 448 2007 318 324 (Pubitemid 47080337)
47. C.W. Wilson, and H.S. Loh Vitamin C and colds Lancet 1 1973 1058 1059
48. J. Yu, M.A. Vodyanik, K. Smuga-Otto, J. Antosiewicz-Bourget, J.L. Frane, S. Tian, J. Nie, G.A. Jonsdottir, V. Ruotti, and R. Stewart Induced pluripotent stem cell lines derived from human somatic cells Science 318 2007 1917 1920
49. S. Zhang, S. Chen, W. Li, X. Guo, P. Zhao, J. Xu, Y. Chen, Q. Pan, X. Liu, and D. Zychlinski Rescue of ATP7B function in hepatocyte-like cells from Wilson's disease induced pluripotent stem cells using gene therapy or the chaperone drug curcumin Hum. Mol. Genet. 20 2011 3176 3187
50. X.Y. Zhao, W. Li, Z. Lv, L. Liu, M. Tong, T. Hai, J. Hao, C.L. Guo, Q.W. Ma, and L. Wang iPS cells produce viable mice through tetraploid complementation Nature 461 2009 86 90
51. T. Zhou, C. Benda, S. Duzinger, Y. Huang, X. Li, Y. Li, X. Guo, G. Cao, S. Chen, and L. Hao Generation of induced pluripotent stem cells from urine J. Am. Soc. Nephrol. 22 2011 1221 1228
52. S. Zhu, W. Li, H. Zhou, W. Wei, R. Ambasudhan, T. Lin, J. Kim, K. Zhang, and S. Ding Reprogramming of human primary somatic cells by OCT4 and chemical compounds Cell Stem Cell 7 2010 651 655