Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

PLoS Biology

Volumn 5, Issue 8, 2007, Pages 1750-1762

  Chambers, Stuart M ^a   Shaw, Chad A ^a   Gatza, Catherine ^a   Fisk, C Joseph ^a   Donehower, Lawrence A ^a   Goodell, Margaret A ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MUTANT PROTEIN; PADGEM PROTEIN; PROTEIN P53;

AGING; ALLELE; ANIMAL CELL; ARTICLE; CELL COUNT; CELL FUNCTION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOME; CONTROLLED STUDY; DOWN REGULATION; EPIGENETICS; GENE EXPRESSION; GENE IDENTIFICATION; GENE INDUCTION; GENE REPRESSION; GENOMICS; HEMATOPOIETIC STEM CELL; INFLAMMATION; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN AGGREGATION; STRESS; TRANSCRIPTION REGULATION; UPREGULATION;

MUS;

EID: 34548208677     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0050201     Document Type: Article

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