-
1
-
-
0037924433
-
Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene
-
Bachman, K.E., Park, B.H., Rhee, I., et al. (2003) Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene. Cancer Cell 3, 89-95.
-
(2003)
Cancer Cell
, vol.3
, pp. 89-95
-
-
Bachman, K.E.1
Park, B.H.2
Rhee, I.3
-
2
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird, A. (2002) DNA methylation patterns and epigenetic memory. Genes Dev. 16, 6-21.
-
(2002)
Genes Dev.
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
3
-
-
4544223707
-
Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L
-
Bourc'his, D. & Bestor, T.H. (2004) Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L. Nature 431, 96-99.
-
(2004)
Nature
, vol.431
, pp. 96-99
-
-
Bourc'his, D.1
Bestor, T.H.2
-
4
-
-
0042132027
-
Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
-
Chen, T., Ueda, Y., Dodge, J.E., Wang, Z. & Li, E. (2003) Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol. Cell. Biol. 23, 5594-5605.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 5594-5605
-
-
Chen, T.1
Ueda, Y.2
Dodge, J.E.3
Wang, Z.4
Li, E.5
-
5
-
-
0028096611
-
High sensitivity mapping of methylated cytosines
-
Clark, S.J., Harrison, J., Paul, C.L. & Frommer, M. (1994) High sensitivity mapping of methylated cytosines. Nucleic Acids Res. 22, 2990-2997.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 2990-2997
-
-
Clark, S.J.1
Harrison, J.2
Paul, C.L.3
Frommer, M.4
-
6
-
-
24044481947
-
Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization
-
Dodge, J.E., Okano, M., Dick, F., et al. (2005) Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization. J. Biol. Chem. 280, 17986-17991.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17986-17991
-
-
Dodge, J.E.1
Okano, M.2
Dick, F.3
-
7
-
-
0242584454
-
Chromosomal instability and tumors promoted by DNA hypomethylation
-
Eden, A., Gaudet, F., Waghmare, A. & Jaenisch, R. (2003) Chromosomal instability and tumors promoted by DNA hypomethylation. Science 300, 455.
-
(2003)
Science
, vol.300
, pp. 455
-
-
Eden, A.1
Gaudet, F.2
Waghmare, A.3
Jaenisch, R.4
-
8
-
-
29244469466
-
The epigenetic progenitor origin of human cancer
-
Feinberg, A.P., Ohlsson, R. & Henikoff, S. (2006) The epigenetic progenitor origin of human cancer. Nat. Rev. Genet. 7, 21-33.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 21-33
-
-
Feinberg, A.P.1
Ohlsson, R.2
Henikoff, S.3
-
9
-
-
0032772371
-
Methylation-mediated transcriptional silencing in euchromatin by methyl-CpG binding protein MBD1 isoforms
-
Fujita, N., Takebayashi, S., Okumura, K., et al. (1999) Methylation-mediated transcriptional silencing in euchromatin by methyl-CpG binding protein MBD1 isoforms. Mol. Cell. Biol. 19, 6415-6426.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6415-6426
-
-
Fujita, N.1
Takebayashi, S.2
Okumura, K.3
-
10
-
-
0037591867
-
Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression
-
Fujita, N., Watanabe, S., Ichimura, T., et al. (2003) Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression. J. Biol. Chem. 278, 24132-24138.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 24132-24138
-
-
Fujita, N.1
Watanabe, S.2
Ichimura, T.3
-
11
-
-
0242584449
-
Induction of tumors in mice by genomic hypomethylation
-
Gaudet, F., Hodgson, J.G., Eden, A., et al. (2003) Induction of tumors in mice by genomic hypomethylation. Science 300, 489-492.
-
(2003)
Science
, vol.300
, pp. 489-492
-
-
Gaudet, F.1
Hodgson, J.G.2
Eden, A.3
-
12
-
-
0036768615
-
Epigenetic reprogramming in mouse primordial germ cells
-
Hajkova, P., Erhardt, S., Lane, N., et al. (2002) Epigenetic reprogramming in mouse primordial germ cells. Mech. Dev. 117, 15-23.
-
(2002)
Mech. Dev.
, vol.117
, pp. 15-23
-
-
Hajkova, P.1
Erhardt, S.2
Lane, N.3
-
13
-
-
28744442731
-
Meiotic and epigenetic aberrations in Dnmt3L -deficient male germ cells
-
Hata, K., Kusumi, M., Yokomine, T., Li, E. & Sasaki, H. (2006) Meiotic and epigenetic aberrations in Dnmt3L -deficient male germ cells. Mol. Reprod. Dev. 73, 116-122.
-
(2006)
Mol Reprod. Dev.
, vol.73
, pp. 116-122
-
-
Hata, K.1
Kusumi, M.2
Yokomine, T.3
Li, E.4
Sasaki, H.5
-
14
-
-
5144231886
-
1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation
-
1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation. Proc. Natl. Acad. Sci. USA 101, 14443-14448.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 14443-14448
-
-
Hong, Y.1
Stambrook, P.J.2
-
15
-
-
4744372577
-
Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells
-
Jackson, M., Krassowska, A., Gilbert, N., et al. (2004) Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells. Mol. Cell. Biol. 24, 8862-8871.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8862-8871
-
-
Jackson, M.1
Krassowska, A.2
Gilbert, N.3
-
16
-
-
0037041422
-
Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase
-
Jackson, J.P., Lindroth, A.M., Cao, X. & Jacobsen, S.E. (2002) Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase. Nature 416, 556-560.
-
(2002)
Nature
, vol.416
, pp. 556-560
-
-
Jackson, J.P.1
Lindroth, A.M.2
Cao, X.3
Jacobsen, S.E.4
-
17
-
-
0035158704
-
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
-
Jackson-Grusby, L., Beard, C., Possemato, R., et al. (2001) Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nat. Genet. 27, 31-39.
-
(2001)
Nat. Genet.
, vol.27
, pp. 31-39
-
-
Jackson-Grusby, L.1
Beard, C.2
Possemato, R.3
-
18
-
-
0035839136
-
Translating the histone code
-
Jenuwein, T. & Allis, C.D. (2001) Translating the histone code. Science 293, 1074-1080.
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
19
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones, P.A. & Baylin, S.B. (2002) The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3, 415-428.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
20
-
-
0031837109
-
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
-
Jones, P.L., Veenstra, G.C.J., Wade, P.A., et al. (1998) Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat. Genet. 19, 187-191.
-
(1998)
Nat. Genet.
, vol.19
, pp. 187-191
-
-
Jones, P.L.1
Veenstra, G.C.J.2
Wade, P.A.3
-
21
-
-
2942718698
-
Histone code modifications on pluripotential nuclei of reprogrammed somatic cells
-
Kimura, H., Tada, M., Nakatsuji, N. & Tada, T. (2004) Histone code modifications on pluripotential nuclei of reprogrammed somatic cells. Mol. Cell. Biol. 24, 5710-5720.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 5710-5720
-
-
Kimura, H.1
Tada, M.2
Nakatsuji, N.3
Tada, T.4
-
22
-
-
10744230544
-
Suv39h -mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin
-
Lehnertz, B., Ueda, Y., Derijck, A.A.H.A., et al. (2003) Suv39h -mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin. Curr. Biol. 13, 1192-1200.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1192-1200
-
-
Lehnertz, B.1
Ueda, Y.2
Derijck, A.A.H.A.3
-
23
-
-
0029803192
-
De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells
-
Lei, H., Oh, S.P., Okano, M., et al. (1996) De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells. Development 122, 3195-3205.
-
(1996)
Development
, vol.122
, pp. 3195-3205
-
-
Lei, H.1
Oh, S.P.2
Okano, M.3
-
24
-
-
0036733675
-
Chromatin modification and epigenetic reprogramming in mammalian development
-
Li, E. (2002) Chromatin modification and epigenetic reprogramming in mammalian development. Nat. Rev. Genet. 3, 662-673.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 662-673
-
-
Li, E.1
-
25
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li, E., Bestor, T.H. & Jaenisch, R. (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915-926.
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
26
-
-
18844404733
-
DNA CpG hypomethylation induces heterochromatin reorganization involving the histone variant macroH2A
-
Ma, Y., Jacobs, S.B., Jackson-Grusby, L., et al. (2005) DNA CpG hypomethylation induces heterochromatin reorganization involving the histone variant macroH2A. J. Cell Sci. 118, 1607-1616.
-
(2005)
J. Cell Sci.
, vol.118
, pp. 1607-1616
-
-
Ma, Y.1
Jacobs, S.B.2
Jackson-Grusby, L.3
-
27
-
-
1842733449
-
HP1 and the dynamics of heterochromatin maintenance
-
Maison, C. & Almouzni, G. (2004) HP1 and the dynamics of heterochromatin maintenance. Nat. Rev. Mol. Cell Biol. 5, 296-304.
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 296-304
-
-
Maison, C.1
Almouzni, G.2
-
28
-
-
29744447772
-
Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells
-
Meshorer, E., Yellajoshula, D., George, E., Scambler, P.J., Brown, D.T. & Misteli, T. (2006) Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. Dev. Cell 10, 105-116.
-
(2006)
Dev. Cell
, vol.10
, pp. 105-116
-
-
Meshorer, E.1
Yellajoshula, D.2
George, E.3
Scambler, P.J.4
Brown, D.T.5
Misteli, T.6
-
29
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
Nan, X., Ng, H.H., Johnson, C.A., et al. (1998) Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393, 386-389.
-
(1998)
Nature
, vol.393
, pp. 386-389
-
-
Nan, X.1
Ng, H.H.2
Johnson, C.A.3
-
30
-
-
0032871399
-
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
-
Ng, H.H., Zhang, Y., Hendrich, B., et al. (1999) MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex. Nat. Genet. 23, 58-61.
-
(1999)
Nat. Genet.
, vol.23
, pp. 58-61
-
-
Ng, H.H.1
Zhang, Y.2
Hendrich, B.3
-
31
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano, M., Bell, D.W., Haber, D.A. & Li, E. (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99, 247-257.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
32
-
-
0034625064
-
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a
-
Ramsahoye, B.H., Biniszkiewicz, D., Lyko, F., Clark, V., Bird, A.P. & Jaenisch, R. (2000) Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc. Natl. Acad. Sci. USA 97, 5237-5242.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5237-5242
-
-
Ramsahoye, B.H.1
Biniszkiewicz, D.2
Lyko, F.3
Clark, V.4
Bird, A.P.5
Jaenisch, R.6
-
33
-
-
18344390653
-
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
-
Rhee, I., Bachman, K.E., Park, B.H., et al. (2002) DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 416, 552-556.
-
(2002)
Nature
, vol.416
, pp. 552-556
-
-
Rhee, I.1
Bachman, K.E.2
Park, B.H.3
-
34
-
-
22844457491
-
DNA methylation and human diseases
-
Robertson, K.D. (2005) DNA methylation and human diseases. Nat. Rev. Genet. 6, 597-610.
-
(2005)
Nat. Rev. Genet.
, vol.6
, pp. 597-610
-
-
Robertson, K.D.1
-
35
-
-
4344685735
-
Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly
-
Sarraf, S.A. & Stancheva, I. (2004) Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly. Mol. Cell 15, 595-605.
-
(2004)
Mol. Cell
, vol.15
, pp. 595-605
-
-
Sarraf, S.A.1
Stancheva, I.2
-
36
-
-
0035891265
-
A histone H3 methyltransferase controls DNA methylation in Neurospora crassa
-
Tamaru, H. & Selker, E.U. (2001) A histone H3 methyltransferase controls DNA methylation in Neurospora crassa. Nature 414, 277-283.
-
(2001)
Nature
, vol.414
, pp. 277-283
-
-
Tamaru, H.1
Selker, E.U.2
-
37
-
-
0041806583
-
Erasure of CpG methylation in Arabidopsis alters patterns of histone H3 methylation in heterochromatin
-
Tariq, M., Saze, H., Probst, A.V., Lichota, J., Habu, Y. & Paszkowski, J. (2003) Erasure of CpG methylation in Arabidopsis alters patterns of histone H3 methylation in heterochromatin. Proc. Natl. Acad. Sci. USA 100, 8823-8827.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8823-8827
-
-
Tariq, M.1
Saze, H.2
Probst, A.V.3
Lichota, J.4
Habu, Y.5
Paszkowski, J.6
-
38
-
-
32844459336
-
The Polycomb group protein EZH2 directly controls DNA methylation
-
Vire, E., Brenner, C., Deplus, R., et al. (2006) The Polycomb group protein EZH2 directly controls DNA methylation. Nature 439, 871-874.
-
(2006)
Nature
, vol.439
, pp. 871-874
-
-
Vire, E.1
Brenner, C.2
Deplus, R.3
-
39
-
-
0032845039
-
Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation
-
Wade, P.A., Gegonne, A., Jones, P.L., Ballestar, E., Aubry, F. & Wolffe, A.P. (1999) Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation. Nat. Genet. 23, 62-66.
-
(1999)
Nat. Genet.
, vol.23
, pp. 62-66
-
-
Wade, P.A.1
Gegonne, A.2
Jones, P.L.3
Ballestar, E.4
Aubry, F.5
Wolffe, A.P.6
-
40
-
-
0031662164
-
Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
-
Walsh, C.P., Chaillet, J.R. & Bestor, T.H. (1998) Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nat. Genet. 20, 116-117.
-
(1998)
Nat. Genet.
, vol.20
, pp. 116-117
-
-
Walsh, C.P.1
Chaillet, J.R.2
Bestor, T.H.3
-
41
-
-
0033547330
-
Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
-
Xu, G.L., Bestor, T.H., Bourc'his, D., et al. (1999) Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature 402, 187-191.
-
(1999)
Nature
, vol.402
, pp. 187-191
-
-
Xu, G.L.1
Bestor, T.H.2
Bourc'his, D.3
-
42
-
-
0141642008
-
Lsh, a modulator of CpG methylation, is crucial for normal histone methylation
-
Yan, Q., Huang, J., Fan, T., Zhu, H. & Muegge, K. (2003) Lsh, a modulator of CpG methylation, is crucial for normal histone methylation. EMBO J. 22, 5154-5162.
-
(2003)
EMBO J.
, vol.22
, pp. 5154-5162
-
-
Yan, Q.1
Huang, J.2
Fan, T.3
Zhu, H.4
Muegge, K.5
-
43
-
-
0033180082
-
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation
-
Zhang, Y., Ng, H.H., Erdjument-Bromage, H., Tempst, P., Bird, A. & Reinberg, D. (1999) Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation. Genes Dev. 13, 1924-1935.
-
(1999)
Genes Dev.
, vol.13
, pp. 1924-1935
-
-
Zhang, Y.1
Ng, H.H.2
Erdjument-Bromage, H.3
Tempst, P.4
Bird, A.5
Reinberg, D.6
|