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Volumn 32, Issue 11, 2014, Pages 3031-3036

Brief reports: A distinct DNA methylation signature defines breast cancer stem cells and predicts cancer outcome

Author keywords

Breast cancer; Cancer stem cells; Differentiation; Methylation

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

EID: 84907905879     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1792     Document Type: Article
Times cited : (35)

References (30)
  • 1
    • 84867878045 scopus 로고    scopus 로고
    • Cancer stem cell definitions and terminology: The devil is in the details
    • Valent P, Bonnet D, De MR, et al. Cancer stem cell definitions and terminology: The devil is in the details. Nat Rev Cancer 2012; 12: 767-775.
    • (2012) Nat Rev Cancer , vol.12 , pp. 767-775
    • Valent, P.1    Bonnet, D.2    De, M. R.3
  • 2
    • 84862517728 scopus 로고    scopus 로고
    • Cancer stem cells: Current status and evolving complexities
    • Visvader JE, Lindeman GJ,. Cancer stem cells: Current status and evolving complexities. Cell Stem Cell 2012; 10: 717-728.
    • (2012) Cell Stem Cell , vol.10 , pp. 717-728
    • Visvader, J.E.1    Lindeman, G.J.2
  • 3
    • 84884377472 scopus 로고    scopus 로고
    • Tumour heterogeneity and cancer cell plasticity
    • Meacham CE, Morrison SJ,. Tumour heterogeneity and cancer cell plasticity. Nature 2013; 501: 328-337.
    • (2013) Nature , vol.501 , pp. 328-337
    • Meacham, C.E.1    Morrison, S.J.2
  • 4
    • 77957591579 scopus 로고    scopus 로고
    • Targeting breast cancer stem cells
    • Liu S, Wicha MS,. Targeting breast cancer stem cells. J Clin Oncol 2010; 28: 4006-4012.
    • (2010) J Clin Oncol , vol.28 , pp. 4006-4012
    • Liu, S.1    Wicha, M.S.2
  • 5
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A,. DNA methylation patterns and epigenetic memory. Genes Dev 2002; 16: 6-21.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 6
    • 84865369147 scopus 로고    scopus 로고
    • DNA methylation dynamics during in vivo differentiation of blood and skin stem cells
    • Bock C, Beerman I, Lien WH, et al. DNA methylation dynamics during in vivo differentiation of blood and skin stem cells. Mol Cell 2012; 47: 633-647.
    • (2012) Mol Cell , vol.47 , pp. 633-647
    • Bock, C.1    Beerman, I.2    Lien, W.H.3
  • 7
    • 52949122883 scopus 로고    scopus 로고
    • Cell type-specific DNA methylation patterns in the human breast
    • Bloushtain-Qimron N, Yao J, Snyder EL, et al. Cell type-specific DNA methylation patterns in the human breast. Proc Natl Acad Sci USA 2008; 105: 14076-14081.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14076-14081
    • Bloushtain-Qimron, N.1    Yao, J.2    Snyder, E.L.3
  • 8
    • 79955631509 scopus 로고    scopus 로고
    • Epigenetic regulation of cell type-specific expression patterns in the human mammary epithelium
    • Maruyama R, Choudhury S, Kowalczyk A, et al. Epigenetic regulation of cell type-specific expression patterns in the human mammary epithelium. PLoS Genet 2011; 7: e1001369.
    • (2011) PLoS Genet , vol.7 , pp. e1001369
    • Maruyama, R.1    Choudhury, S.2    Kowalczyk, A.3
  • 9
    • 84874231902 scopus 로고    scopus 로고
    • Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2
    • Pal B, Bouras T, Shi W, et al. Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2. Cell Rep 2013; 3: 411-426.
    • (2013) Cell Rep , vol.3 , pp. 411-426
    • Pal, B.1    Bouras, T.2    Shi, W.3
  • 10
    • 84890293037 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor abexinostat induces cancer stem cells differentiation in breast cancer with low Xist expression
    • Salvador MA, Wicinski J, Cabaud O, et al. The histone deacetylase inhibitor abexinostat induces cancer stem cells differentiation in breast cancer with low Xist expression. Clin Cancer Res 2013; 19: 6520-6531.
    • (2013) Clin Cancer Res , vol.19 , pp. 6520-6531
    • Salvador, M.A.1    Wicinski, J.2    Cabaud, O.3
  • 11
    • 84863337757 scopus 로고    scopus 로고
    • Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells
    • Tsai HC, Li H, Van NL, et al. Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells. Cancer Cell 2012; 21: 430-446.
    • (2012) Cancer Cell , vol.21 , pp. 430-446
    • Tsai, H.C.1    Li, H.2    Van, N.L.3
  • 12
    • 79954457432 scopus 로고    scopus 로고
    • Methylome analysis reveals Jak-STAT pathway deregulation in putative breast cancer stem cells
    • Hernandez-Vargas H, Ouzounova M, Le Calvez-Kelm F, et al. Methylome analysis reveals Jak-STAT pathway deregulation in putative breast cancer stem cells. Epigenetics 2011; 6: 428-439.
    • (2011) Epigenetics , vol.6 , pp. 428-439
    • Hernandez-Vargas, H.1    Ouzounova, M.2    Le Calvez-Kelm, F.3
  • 13
    • 60549111070 scopus 로고    scopus 로고
    • Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature
    • Charafe-Jauffret E, Ginestier C, Iovino F, et al. Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res 2009; 69: 1302-1313.
    • (2009) Cancer Res , vol.69 , pp. 1302-1313
    • Charafe-Jauffret, E.1    Ginestier, C.2    Iovino, F.3
  • 14
    • 33846569960 scopus 로고    scopus 로고
    • A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
    • Ohm JE, McGarvey KM, Yu X, et al. A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet 2007; 39: 237-242.
    • (2007) Nat Genet , vol.39 , pp. 237-242
    • Ohm, J.E.1    McGarvey, K.M.2    Yu, X.3
  • 15
    • 33846576622 scopus 로고    scopus 로고
    • Epigenetic stem cell signature in cancer
    • Widschwendter M, Fiegl H, Egle D, et al. Epigenetic stem cell signature in cancer. Nat Genet 2007; 39: 157-158.
    • (2007) Nat Genet , vol.39 , pp. 157-158
    • Widschwendter, M.1    Fiegl, H.2    Egle, D.3
  • 16
    • 29244469466 scopus 로고    scopus 로고
    • The epigenetic progenitor origin of human cancer
    • Feinberg AP, Ohlsson R, Henikoff S,. The epigenetic progenitor origin of human cancer. Nat Rev Genet 2006; 7: 21-33.
    • (2006) Nat Rev Genet , vol.7 , pp. 21-33
    • Feinberg, A.P.1    Ohlsson, R.2    Henikoff, S.3
  • 17
    • 80052918929 scopus 로고    scopus 로고
    • Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment
    • Hodges E, Molaro A, Dos Santos CO, et al. Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment. Mol Cell 2011; 44: 17-28.
    • (2011) Mol Cell , vol.44 , pp. 17-28
    • Hodges, E.1    Molaro, A.2    Dos Santos, C.O.3
  • 18
    • 77956902023 scopus 로고    scopus 로고
    • Comprehensive methylome map of lineage commitment from haematopoietic progenitors
    • Ji H, Ehrlich LI, Seita J, et al. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature 2010; 467: 338-342.
    • (2010) Nature , vol.467 , pp. 338-342
    • Ji, H.1    Ehrlich, L.I.2    Seita, J.3
  • 19
    • 84897498801 scopus 로고    scopus 로고
    • Candidate luminal B breast cancer genes identified by genome, gene expression and DNA methylation profiling
    • Cornen S, Guille A, Adelaide J, et al. Candidate luminal B breast cancer genes identified by genome, gene expression and DNA methylation profiling. PLoS One 2014; 9: e81843.
    • (2014) PLoS One , vol.9 , pp. e81843
    • Cornen, S.1    Guille, A.2    Adelaide, J.3
  • 20
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, Guo W, Liao MJ, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008; 133: 704-715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3
  • 21
    • 84874607100 scopus 로고    scopus 로고
    • TGF-beta inhibition enhances chemotherapy action against triple-negative breast cancer
    • Bhola NE, Balko JM, Dugger TC, et al. TGF-beta inhibition enhances chemotherapy action against triple-negative breast cancer. J Clin Invest 2013; 123: 1348-1358.
    • (2013) J Clin Invest , vol.123 , pp. 1348-1358
    • Bhola, N.E.1    Balko, J.M.2    Dugger, T.C.3
  • 22
    • 84867027347 scopus 로고    scopus 로고
    • TGFbeta induces the formation of tumour-initiating cells in claudinlow breast cancer
    • Bruna A, Greenwood W, Le QJ, et al. TGFbeta induces the formation of tumour-initiating cells in claudinlow breast cancer. Nat Commun 2012; 3: 1055.
    • (2012) Nat Commun , vol.3 , pp. 1055
    • Bruna, A.1    Greenwood, E.2    Le, Q.J.3
  • 23
    • 84879983245 scopus 로고    scopus 로고
    • Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity
    • Chaffer CL, Marjanovic ND, Lee T, et al. Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell 2013; 154: 61-74.
    • (2013) Cell , vol.154 , pp. 61-74
    • Chaffer, C.L.1    Marjanovic, N.D.2    Lee, T.3
  • 24
    • 84861968669 scopus 로고    scopus 로고
    • TGF-beta-dependent active demethylation and expression of the p15ink4b tumor suppressor are impaired by the ZNF217/CoREST complex
    • Thillainadesan G, Chitilian JM, Isovic M, et al. TGF-beta-dependent active demethylation and expression of the p15ink4b tumor suppressor are impaired by the ZNF217/CoREST complex. Mol Cell 2012; 46: 636-649.
    • (2012) Mol Cell , vol.46 , pp. 636-649
    • Thillainadesan, G.1    Chitilian, J.M.2    Isovic, M.3
  • 25
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
    • Ginestier C, Hur MH, Charafe-Jauffret E, et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 2007; 1: 555-567.
    • (2007) Cell Stem Cell , vol.1 , pp. 555-567
    • Ginestier, C.1    Hur, M.H.2    Charafe-Jauffret, E.3
  • 26
    • 74949129868 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer
    • Charafe-Jauffret E, Ginestier C, Iovino F, et al. Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer. Clin Cancer Res 2010; 16: 45-55.
    • (2010) Clin Cancer Res , vol.16 , pp. 45-55
    • Charafe-Jauffret, E.1    Ginestier, C.2    Iovino, F.3
  • 27
    • 73149110562 scopus 로고    scopus 로고
    • Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
    • Pece S, Tosoni D, Confalonieri S, et al. Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell 2010; 140: 62-73.
    • (2010) Cell , vol.140 , pp. 62-73
    • Pece, S.1    Tosoni, D.2    Confalonieri, S.3
  • 28
    • 66249109653 scopus 로고    scopus 로고
    • Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics
    • Hennessy BT, Gonzalez-Angulo AM, Stemke-Hale K, et al. Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics. Cancer Res 2009; 69: 4116-4124.
    • (2009) Cancer Res , vol.69 , pp. 4116-4124
    • Hennessy, B.T.1    Gonzalez-Angulo, A.M.2    Stemke-Hale, K.3
  • 29
    • 33846425793 scopus 로고    scopus 로고
    • The prognostic role of a gene signature from tumorigenic breast-cancer cells
    • Liu R, Wang X, Chen GY, et al. The prognostic role of a gene signature from tumorigenic breast-cancer cells. N Engl J Med 2007; 356: 217-226.
    • (2007) N Engl J Med , vol.356 , pp. 217-226
    • Liu, R.1    Wang, X.2    Chen, G.Y.3
  • 30
    • 84891278007 scopus 로고    scopus 로고
    • ALDH1-positive cancer stem cells predict engraftment of primary breast tumors and are governed by a common stem cell program
    • Charafe-Jauffret E, Ginestier C, Bertucci F, et al. ALDH1-positive cancer stem cells predict engraftment of primary breast tumors and are governed by a common stem cell program. Cancer Res 2013; 73: 7290-7300.
    • (2013) Cancer Res , vol.73 , pp. 7290-7300
    • Charafe-Jauffret, E.1    Ginestier, C.2    Bertucci, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.