-
1
-
-
33745525505
-
Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus
-
Blelloch R, Wang Z, Meissner A, Pollard S, Smith A, Jaenisch R. 2006. Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus. Stem Cells 24: 2007-2013.
-
(2006)
Stem Cells
, vol.24
, pp. 2007-2013
-
-
Blelloch, R.1
Wang, Z.2
Meissner, A.3
Pollard, S.4
Smith, A.5
Jaenisch, R.6
-
2
-
-
69949104478
-
Adult mice generated from induced pluripotent stem cells
-
Boland MJ, Hazen JL, Nazor KL, Rodriguez AR, Gifford W, Martin G, Kupriyanov S, Baldwin KK. 2009. Adult mice generated from induced pluripotent stem cells. Nature 461: 91-94.
-
(2009)
Nature
, vol.461
, pp. 91-94
-
-
Boland, M.J.1
Hazen, J.L.2
Nazor, K.L.3
Rodriguez, A.R.4
Gifford, W.5
Martin, G.6
Kupriyanov, S.7
Baldwin, K.K.8
-
3
-
-
38649094609
-
Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells
-
Brambrink T, Foreman R, Welstead GG, Lengner CJ, Wernig M, Suh H, Jaenisch R. 2008. Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. Cell Stem Cell 2: 151-159.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 151-159
-
-
Brambrink, T.1
Foreman, R.2
Welstead, G.G.3
Lengner, C.J.4
Wernig, M.5
Suh, H.6
Jaenisch, R.7
-
4
-
-
0021139979
-
Cell lineage-specific undermethylation of mouse repetitive DNA
-
Chapman V, Forrester L, Sanford J, Hastie N, Rossant J. 1984. Cell lineage-specific undermethylation of mouse repetitive DNA. Nature 307: 284-286.
-
(1984)
Nature
, vol.307
, pp. 284-286
-
-
Chapman, V.1
Forrester, L.2
Sanford, J.3
Hastie, N.4
Rossant, J.5
-
5
-
-
0042132027
-
Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
-
Chen T, Ueda Y, Dodge JE, Wang Z, Li E. 2003. Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol Cell Biol 23: 5594-5605.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5594-5605
-
-
Chen, T.1
Ueda, Y.2
Dodge, J.E.3
Wang, Z.4
Li, E.5
-
6
-
-
64349106730
-
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming
-
Deng J, Shoemaker R, Xie B, Gore A, LeProust EM, Antosiewicz-Bourget J, Egli D, Maherali N, Park IH, Yu J, et al. 2009. Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nat Biotechnol 27: 353-360.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 353-360
-
-
Deng, J.1
Shoemaker, R.2
Xie, B.3
Gore, A.4
Leproust, E.M.5
Antosiewicz-Bourget, J.6
Egli, D.7
Maherali, N.8
Park, I.H.9
Yu, J.10
-
7
-
-
24044481947
-
Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization
-
Dodge JE, Okano M, Dick F, Tsujimoto N, Chen T, Wang S, Ueda Y, Dyson N, Li E. 2005. Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization. J Biol Chem 280: 17986-17991.
-
(2005)
J Biol Chem
, vol.280
, pp. 17986-17991
-
-
Dodge, J.E.1
Okano, M.2
Dick, F.3
Tsujimoto, N.4
Chen, T.5
Wang, S.6
Ueda, Y.7
Dyson, N.8
Li, E.9
-
8
-
-
70649095120
-
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells, and fibroblasts
-
Doi A, Park IH, Wen B, Murakami P, Aryee MJ, Irizarry R, Herb B, Ladd-Acosta C, Rho J, Loewer S, et al. 2009. Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells, and fibroblasts. Nat Genet 41: 1350-1353.
-
(2009)
Nat Genet
, vol.41
, pp. 1350-1353
-
-
Doi, A.1
Park, I.H.2
Wen, B.3
Murakami, P.4
Aryee, M.J.5
Irizarry, R.6
Herb, B.7
Ladd-Acosta, C.8
Rho, J.9
Loewer, S.10
-
9
-
-
33645132331
-
G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis
-
Feldman N, Gerson A, Fang J, Li E, Zhang Y, Shinkai Y, Cedar H, Bergman Y. 2006. G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis. Nat Cell Biol 8: 188-194.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 188-194
-
-
Feldman, N.1
Gerson, A.2
Fang, J.3
Li, E.4
Zhang, Y.5
Shinkai, Y.6
Cedar, H.7
Bergman, Y.8
-
10
-
-
38649126918
-
Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation
-
Fouse SD, Shen Y, Pellegrini M, Cole S, Meissner A, Van Neste L, Jaenisch R, Fan G. 2008. Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell Stem Cell 2: 160-169.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 160-169
-
-
Fouse, S.D.1
Shen, Y.2
Pellegrini, M.3
Cole, S.4
Meissner, A.5
van Neste, L.6
Jaenisch, R.7
Fan, G.8
-
11
-
-
37549030199
-
Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
-
Hanna J, Wernig M, Markoulaki S, Sun CW, Meissner A, Cassady JP, Beard C, Brambrink T, Wu LC, Townes TM, et al. 2007. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 318: 1920-1923.
-
(2007)
Science
, vol.318
, pp. 1920-1923
-
-
Hanna, J.1
Wernig, M.2
Markoulaki, S.3
Sun, C.W.4
Meissner, A.5
Cassady, J.P.6
Beard, C.7
Brambrink, T.8
Wu, L.C.9
Townes, T.M.10
-
12
-
-
67349183976
-
Metastable pluripotent states in NOD-mouse-derived ESCs
-
Hanna J, Markoulaki S, Mitalipova M, Cheng AW, Cassady JP, Staerk J, Carey BW, Lengner CJ, Foreman R, Love J, et al. 2009. Metastable pluripotent states in NOD-mouse-derived ESCs. Cell Stem Cell 4: 513-524.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 513-524
-
-
Hanna, J.1
Markoulaki, S.2
Mitalipova, M.3
Cheng, A.W.4
Cassady, J.P.5
Staerk, J.6
Carey, B.W.7
Lengner, C.J.8
Foreman, R.9
Love, J.10
-
13
-
-
64249157351
-
Epigenetic reprogramming and induced pluripotency
-
Hochedlinger K, Plath K. 2009. Epigenetic reprogramming and induced pluripotency. Development 136: 509-523.
-
(2009)
Development
, vol.136
, pp. 509-523
-
-
Hochedlinger, K.1
Plath, K.2
-
14
-
-
50849144675
-
A drug-inducible system for direct reprogramming of human somatic cells to pluripotency
-
Hockemeyer D, Soldner F, Cook EG, Gao Q, Mitalipova M, Jaenisch R. 2008. A drug-inducible system for direct reprogramming of human somatic cells to pluripotency. Cell Stem Cell 3: 346-353.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 346-353
-
-
Hockemeyer, D.1
Soldner, F.2
Cook, E.G.3
Gao, Q.4
Mitalipova, M.5
Jaenisch, R.6
-
15
-
-
33748698287
-
Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells
-
doi: 10.1186/1471-213X-6-34
-
Imamura M, Miura K, Iwabuchi K, Ichisaka T, Nakagawa M, Lee J, Kanatsu-Shinohara M, Shinohara T, Yamanaka S. 2006. Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells. BMC Dev Biol 6: 34. doi: 10.1186/1471-213X-6-34.
-
(2006)
BMC Dev Biol
, vol.6
, pp. 34
-
-
Imamura, M.1
Miura, K.2
Iwabuchi, K.3
Ichisaka, T.4
Nakagawa, M.5
Lee, J.6
Kanatsu-Shinohara, M.7
Shinohara, T.8
Yamanaka, S.9
-
16
-
-
3042584653
-
Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting
-
Kaneda M, Okano M, Hata K, Sado T, Tsujimoto N, Li E, Sasaki H. 2004. Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature 429: 900-903.
-
(2004)
Nature
, vol.429
, pp. 900-903
-
-
Kaneda, M.1
Okano, M.2
Hata, K.3
Sado, T.4
Tsujimoto, N.5
Li, E.6
Sasaki, H.7
-
17
-
-
67849133023
-
IPS cells can support fullterm development of tetraploid blastocyst-complemented embryos
-
Kang L, Wang J, Zhang Y, Kou Z, Gao S. 2009. iPS cells can support fullterm development of tetraploid blastocyst-complemented embryos. Cell Stem Cell 5: 135-138.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 135-138
-
-
Kang, L.1
Wang, J.2
Zhang, Y.3
Kou, Z.4
Gao, S.5
-
18
-
-
34548705374
-
Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse
-
Kato Y, Kaneda M, Hata K, Kumaki K, Hisano M, Kohara Y, Okano M, Li E, Nozaki M, Sasaki H. 2007. Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse. Hum Mol Genet 16: 2272-2280.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 2272-2280
-
-
Kato, Y.1
Kaneda, M.2
Hata, K.3
Kumaki, K.4
Hisano, M.5
Kohara, Y.6
Okano, M.7
Li, E.8
Nozaki, M.9
Sasaki, H.10
-
19
-
-
0036733675
-
Chromatin modification and epigenetic reprogramming in mammalian development
-
Li E. 2002. Chromatin modification and epigenetic reprogramming in mammalian development. Nat Rev Genet 3: 662-673.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 662-673
-
-
Li, E.1
-
20
-
-
33645825196
-
Suppression of intestinal neoplasia by deletion of Dnmt3b
-
Lin H, Yamada Y, Nguyen S, Linhart H, Jackson-Grusby L, Meissner A, Meletis K, Lo G, Jaenisch R. 2006. Suppression of intestinal neoplasia by deletion of Dnmt3b. Mol Cell Biol 26: 2976-2983.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2976-2983
-
-
Lin, H.1
Yamada, Y.2
Nguyen, S.3
Linhart, H.4
Jackson-Grusby, L.5
Meissner, A.6
Meletis, K.7
Lo, G.8
Jaenisch, R.9
-
21
-
-
34249909232
-
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
-
Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, Arnold K, Stadtfeld M, Yachechko R, Tchieu J, Jaenisch R, et al. 2007. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1: 55-70.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 55-70
-
-
Maherali, N.1
Sridharan, R.2
Xie, W.3
Utikal, J.4
Eminli, S.5
Arnold, K.6
Stadtfeld, M.7
Yachechko, R.8
Tchieu, J.9
Jaenisch, R.10
-
22
-
-
77950862656
-
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET
-
Matsui T, Leung D, Miyashita H, Maksakova IA, Miyachi H, Kimura H, Tachibana M, Lorincz MC, Shinkai Y. 2010. Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET. Nature 464: 927-931.
-
(2010)
Nature
, vol.464
, pp. 927-931
-
-
Matsui, T.1
Leung, D.2
Miyashita, H.3
Maksakova, I.A.4
Miyachi, H.5
Kimura, H.6
Tachibana, M.7
Lorincz, M.C.8
Shinkai, Y.9
-
23
-
-
27144500218
-
Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis
-
Meissner A, Gnirke A, Bell GW, Ramsahoye B, Lander ES, Jaenisch R. 2005. Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis. Nucleic Acids Res 33: 5868-5877.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 5868-5877
-
-
Meissner, A.1
Gnirke, A.2
Bell, G.W.3
Ramsahoye, B.4
Lander, E.S.5
Jaenisch, R.6
-
24
-
-
49649125042
-
Genomescale DNA methylation maps of pluripotent and differentiated cells
-
Meissner A, Mikkelsen TS, Gu H, Wernig M, Hanna J, Sivachenko A, Zhang X, Bernstein BE, Nusbaum C, Jaffe DB, et al. 2008. Genomescale DNA methylation maps of pluripotent and differentiated cells. Nature 454: 766-770.
-
(2008)
Nature
, vol.454
, pp. 766-770
-
-
Meissner, A.1
Mikkelsen, T.S.2
Gu, H.3
Wernig, M.4
Hanna, J.5
Sivachenko, A.6
Zhang, X.7
Bernstein, B.E.8
Nusbaum, C.9
Jaffe, D.B.10
-
25
-
-
46449094276
-
Dissecting direct reprogramming through integrative genomic analysis
-
Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A. 2008. Dissecting direct reprogramming through integrative genomic analysis. Nature 454: 49-55.
-
(2008)
Nature
, vol.454
, pp. 49-55
-
-
Mikkelsen, T.S.1
Hanna, J.2
Zhang, X.3
Ku, M.4
Wernig, M.5
Schorderet, P.6
Bernstein, B.E.7
Jaenisch, R.8
Lander, E.S.9
Meissner, A.10
-
26
-
-
34250643467
-
Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan
-
Nguyen S, Meletis K, Fu D, Jhaveri S, Jaenisch R. 2007. Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan. Dev Dyn 236: 1663-1676.
-
(2007)
Dev Dyn
, vol.236
, pp. 1663-1676
-
-
Nguyen, S.1
Meletis, K.2
Fu, D.3
Jhaveri, S.4
Jaenisch, R.5
-
27
-
-
33845690061
-
DNA methylation regulates longrange gene silencing of an X-linked homeobox gene cluster in a lineage-specific manner
-
Oda M, Yamagiwa A, Yamamoto S, Nakayama T, Tsumura A, Sasaki H, Nakao K, Li E, Okano M. 2006. DNA methylation regulates longrange gene silencing of an X-linked homeobox gene cluster in a lineage-specific manner. Genes & Dev 20: 3382-3394.
-
(2006)
Genes & Dev
, vol.20
, pp. 3382-3394
-
-
Oda, M.1
Yamagiwa, A.2
Yamamoto, S.3
Nakayama, T.4
Tsumura, A.5
Sasaki, H.6
Nakao, K.7
Li, E.8
Okano, M.9
-
28
-
-
0031860739
-
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
-
Okano M, Xie S, Li E. 1998. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat Genet 19: 219-220.
-
(1998)
Nat Genet
, vol.19
, pp. 219-220
-
-
Okano, M.1
Xie, S.2
Li, E.3
-
29
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA, Li E. 1999. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99: 247-257.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
30
-
-
34249880066
-
Generation of germline-competent induced pluripotent stem cells
-
Okita K, Ichisaka T, Yamanaka S. 2007. Generation of germline-competent induced pluripotent stem cells. Nature 448: 313-317.
-
(2007)
Nature
, vol.448
, pp. 313-317
-
-
Okita, K.1
Ichisaka, T.2
Yamanaka, S.3
-
31
-
-
65249149666
-
Induced pluripotent stem cell generation using a single lentiviral stem cell cassette
-
Sommer CA, Stadtfeld M, Murphy GJ, Hochedlinger K, Kotton DN, Mostoslavsky G. 2009. Induced pluripotent stem cell generation using a single lentiviral stem cell cassette. Stem Cells 27: 543-549.
-
(2009)
Stem Cells
, vol.27
, pp. 543-549
-
-
Sommer, C.A.1
Stadtfeld, M.2
Murphy, G.J.3
Hochedlinger, K.4
Kotton, D.N.5
Mostoslavsky, G.6
-
32
-
-
39149115929
-
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse
-
Stadtfeld M, Maherali N, Breault DT, Hochedlinger K. 2008. Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell 2: 230-240.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 230-240
-
-
Stadtfeld, M.1
Maherali, N.2
Breault, D.T.3
Hochedlinger, K.4
-
33
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. 2006. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
34
-
-
0031662164
-
Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
-
Walsh CP, Chaillet JR, Bestor TH. 1998. Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nat Genet 20: 116-117.
-
(1998)
Nat Genet
, vol.20
, pp. 116-117
-
-
Walsh, C.P.1
Chaillet, J.R.2
Bestor, T.H.3
-
35
-
-
34249908901
-
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
-
Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K, Bernstein BE, Jaenisch R. 2007. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448: 318-324.
-
(2007)
Nature
, vol.448
, pp. 318-324
-
-
Wernig, M.1
Meissner, A.2
Foreman, R.3
Brambrink, T.4
Ku, M.5
Hochedlinger, K.6
Bernstein, B.E.7
Jaenisch, R.8
-
36
-
-
42649130264
-
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
-
Wernig M, Zhao JP, Pruszak J, Hedlund E, Fu D, Soldner F, Broccoli V, Constantine-Paton M, Isacson O, Jaenisch R. 2008. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc Natl Acad Sci 105: 5856-5861.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 5856-5861
-
-
Wernig, M.1
Zhao, J.P.2
Pruszak, J.3
Hedlund, E.4
Fu, D.5
Soldner, F.6
Broccoli, V.7
Constantine-Paton, M.8
Isacson, O.9
Jaenisch, R.10
-
37
-
-
63049090064
-
A fresh look at iPS cells
-
Yamanaka S. 2009. A fresh look at iPS cells. Cell 137: 13-17.
-
(2009)
Cell
, vol.137
, pp. 13-17
-
-
Yamanaka, S.1
-
38
-
-
69949089630
-
IPS cells produce viable mice through tetraploid complementation
-
Zhao XY, Li W, Lv Z, Liu L, Tong M, Hai T, Hao J, Guo CL, Ma QW, Wang L, et al. 2009. iPS cells produce viable mice through tetraploid complementation. Nature 461: 86-90.
-
(2009)
Nature
, vol.461
, pp. 86-90
-
-
Zhao, X.Y.1
Li, W.2
Lv, Z.3
Liu, L.4
Tong, M.5
Hai, T.6
Hao, J.7
Guo, C.L.8
Ma, Q.W.9
Wang, L.10
-
39
-
-
27644478696
-
Global hypomethylation of the genome in XX embryonic stem cells
-
Zvetkova I, Apedaile A, Ramsahoye B, Mermoud JE, Crompton LA, John R, Feil R, Brockdorff N. 2005. Global hypomethylation of the genome in XX embryonic stem cells. Nat Genet 37: 1274-1279.
-
(2005)
Nat Genet
, vol.37
, pp. 1274-1279
-
-
Zvetkova, I.1
Apedaile, A.2
Ramsahoye, B.3
Mermoud, J.E.4
Crompton, L.A.5
John, R.6
Feil, R.7
Brockdorff, N.8
|