메뉴 건너뛰기




Volumn 15, Issue 5, 2015, Pages 458-483

Lipoic acid: Its antioxidant and anti-inflammatory role and clinical applications

Author keywords

Inflammation; Lipoic acid; Oral supplementation; Oxidative stress

Indexed keywords

BIOLOGICAL MARKER; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; THIOCTIC ACID; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; ALPHA TOCOPHEROL; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; ASCORBIC ACID;

EID: 84930905101     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/1568026615666150114161358     Document Type: Article
Times cited : (151)

References (197)
  • 2
    • 69949104384 scopus 로고    scopus 로고
    • Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential
    • Shay, K. P.; Moreau, R. F.; Smith, E. J.; Smith, A. R.; Hagen, T. M. Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochim. Biophys. Acta, 2009, 1790, 1149-1160.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 1149-1160
    • Shay, K.P.1    Moreau, R.F.2    Smith, E.J.3    Smith, A.R.4    Hagen, T.M.5
  • 3
    • 2342544918 scopus 로고    scopus 로고
    • Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress
    • Smith, A. R.; Shenvi, S. V; Widlansky, M.; Suh, J. H.; Hagen, T. M. Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress. Curr. Med. Chem., 2004, 11, 1135-1146.
    • (2004) Curr. Med. Chem , vol.11 , pp. 1135-1146
    • Smith, A.R.1    Shenvi, S.V.2    Widlansky, M.3    Suh, J.H.4    Hagen, T.M.5
  • 4
    • 0029909010 scopus 로고    scopus 로고
    • Neuroprotection by the metabolic antioxidant alpha-lipoic acid
    • Packer, L.; Tritschler, H. J.; Wessel, K. Neuroprotection by the metabolic antioxidant alpha-lipoic acid. Free Radic. Biol. Med., 1997, 22, 359-378.
    • (1997) Free Radic. Biol. Med , vol.22 , pp. 359-378
    • Packer, L.1    Tritschler, H.J.2    Wessel, K.3
  • 5
    • 79953761841 scopus 로고    scopus 로고
    • Guidelines for the management of inflammatory bowel disease in adults
    • Carter, M.; Lobo, A.; Travis, S. Guidelines for the management of inflammatory bowel disease in adults. Gut., 2004, 60, 571-607.
    • (2004) Gut , vol.60 , pp. 571-607
    • Carter, M.1    Lobo, A.2    Travis, S.3
  • 7
    • 78651106044 scopus 로고    scopus 로고
    • Estudos farmacologicos do acido lipoico nas alteracoes comportamentais e na atividade da superoxido dismutase no corpo estriado de ratos apos convulsao induzidas por pilocarpina
    • Freitas, R. M. Estudos farmacologicos do acido lipoico nas alteracoes comportamentais e na atividade da superoxido dismutase no corpo estriado de ratos apos convulsao induzidas por pilocarpina. Rev. Eletrônica Farmácia, 2009, 6 (1), 65-72.
    • (2009) Rev. Eletrônica Farmácia , vol.6 , Issue.1 , pp. 65-72
    • Freitas, R.M.1
  • 8
    • 26844564082 scopus 로고    scopus 로고
    • Oxidative stress and the use of antioxidants in diabetes: Linking basic science to clinical practice
    • Johansen, J. S.; Harris, A. K.; Rychly, D. J.; Ergul, A. Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice. Cardiovasc Diabetol. 2005, 4, 5.
    • (2005) Cardiovasc Diabetol , vol.4 , pp. 5
    • Johansen, J.S.1    Harris, A.K.2    Rychly, D.J.3    Ergul, A.4
  • 9
    • 0036070514 scopus 로고    scopus 로고
    • Antioxidant and Prooxidant Activities of α-Lipoic Acid and Dihydrolipoic Acid
    • Moini, H.; Packer, L.; Saris, N.-E. L. Antioxidant and Prooxidant Activities of α-Lipoic Acid and Dihydrolipoic Acid. Toxicol. Appl. Pharmacol., 2002, 182, 84-90.
    • (2002) Toxicol. Appl. Pharmacol , vol.182 , pp. 84-90
    • Moini, H.1    Packer, L.2    Saris, N.-E.L.3
  • 10
    • 0036619751 scopus 로고    scopus 로고
    • Lipoic acid: A unique antioxidant in the detoxification of activated oxygen species
    • Navari-Izzo, F.; Quartacci, M. F.; Sgherri, C. Lipoic acid: a unique antioxidant in the detoxification of activated oxygen species. Plant Physiol. Biochem., 2002, 40, 463-470.
    • (2002) Plant Physiol. Biochem , vol.40 , pp. 463-470
    • Navari-Izzo, F.1    Quartacci, M.F.2    Sgherri, C.3
  • 12
    • 77953022783 scopus 로고    scopus 로고
    • Inflammation and apoptosis in aortic tissues of aged type II diabetes: Amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt-dependent mechanism
    • Bitar, M. S.; Ayed, A. K.; Abdel-Halim, S. M.; Isenovic, E. R.; Al-Mulla, F. Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt-dependent mechanism. Life Sci. 2010, 86, 844-853.
    • (2010) Life Sci , vol.86 , pp. 844-853
    • Bitar, M.S.1    Ayed, A.K.2    Abdel-Halim, S.M.3    Isenovic, E.R.4    Al-Mulla, F.5
  • 13
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-An inflammatory disease
    • Ross, R. Atherosclerosis-An inflammatory disease. N. Engl. J. Med., 1999, 340, 115-126.
    • (1999) N. Engl. J. Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 16
    • 77957750758 scopus 로고    scopus 로고
    • Mechanisms of LDL oxidation
    • Yoshida, H.; Kisugi, R. Mechanisms of LDL oxidation. Clin. Chim. Acta, 2010, 411, 1875-1882.
    • (2010) Clin. Chim. Acta , vol.411 , pp. 1875-1882
    • Yoshida, H.1    Kisugi, R.2
  • 18
    • 23944462877 scopus 로고    scopus 로고
    • Infection, inflammation, and gastrointestinal cancer
    • Boland, C. R.; Luciani, M. G.; Gasche, C.; Goel, a. Infection, inflammation, and gastrointestinal cancer. Gut., 2005, 54, 1321-1331.
    • (2005) Gut , vol.54 , pp. 1321-1331
    • Boland, C.R.1    Luciani, M.G.2    Gasche, C.3    Goel, A.4
  • 19
    • 33947433224 scopus 로고    scopus 로고
    • Inflammation and oxidative stress in gastroesophageal reflux disease
    • Yoshida, N. Inflammation and oxidative stress in gastroesophageal reflux disease. J. Clin. Biochem. Nutr., 2007, 40, 13-23.
    • (2007) J. Clin. Biochem. Nutr , vol.40 , pp. 13-23
    • Yoshida, N.1
  • 20
    • 84883551010 scopus 로고    scopus 로고
    • Cytokine Adiponectin in inflammatory and immunemediated diseases
    • Fantuzzi, G. Cytokine Adiponectin in inflammatory and immunemediated diseases. Cytokine, 2013, 64, 1-10.
    • (2013) Cytokine , vol.64 , pp. 1-10
    • Fantuzzi, G.1
  • 21
    • 84876896360 scopus 로고    scopus 로고
    • Targeting the redox balance in inflammatory skin conditions
    • Wagener, F. a D. T. G.; Carels, C. E.; Lundvig, D. M. S. Targeting the redox balance in inflammatory skin conditions. Int. J. Mol. Sci., 2013, 14, 9126-9167.
    • (2013) Int. J. Mol. Sci , vol.14 , pp. 9126-9167
    • Wagener, F.D.T.G.1    Carels, C.E.2    Lundvig, D.M.S.3
  • 23
    • 0021763962 scopus 로고
    • Free-radical mechanisms in tissue injury
    • Slater, T. F. Free-radical mechanisms in tissue injury. Biochem. J., 1984, 222, 1-15.
    • (1984) Biochem. J , vol.222 , pp. 1-15
    • Slater, T.F.1
  • 25
    • 4344696207 scopus 로고    scopus 로고
    • Alpha-Lipoic acid inhibits airway inflammation and hyperresponsiveness in a mouse model of asthma
    • Cho, Y. S.; Lee, J.; Lee, T.-H.; Lee, E. Y.; Lee, K.-U.; Park, J. Y.; Moon, H.-B. Alpha-Lipoic acid inhibits airway inflammation and hyperresponsiveness in a mouse model of asthma. J. Allergy Clin. Immunol., 2004, 114, 429-435.
    • (2004) J. Allergy Clin. Immunol , vol.114 , pp. 429-435
    • Cho, Y.S.1    Lee, J.2    Lee, T.-H.3    Lee, E.Y.4    Lee, K.-U.5    Park, J.Y.6    Moon, H.-B.7
  • 26
    • 84859165038 scopus 로고    scopus 로고
    • Dextran sulfate sodium-induced ulcerative colitis leads to increased hematopoiesis and induces both local as well as systemic genotoxicity in mice
    • Trivedi, P. P.; Jena, G. B. Dextran sulfate sodium-induced ulcerative colitis leads to increased hematopoiesis and induces both local as well as systemic genotoxicity in mice. Mutat. Res., 2012, 744, 172-183.
    • (2012) Mutat. Res , vol.744 , pp. 172-183
    • Trivedi, P.P.1    Jena, G.B.2
  • 27
    • 84880770415 scopus 로고    scopus 로고
    • Decreased O-GlcN Acylation of the key proteins in kinase and redox signalling pathways is a novel mechanism of the beneficial effect of α-lipoic acid in diabetic liver
    • Dinić, S.; Arambašić, J.; Mihailović, M.; Uskoković, A.; Grdović, N.; Marković, J.; Karadžić, B.; Poznanović, G.; Vidaković, M. Decreased O-GlcN Acylation of the key proteins in kinase and redox signalling pathways is a novel mechanism of the beneficial effect of α-lipoic acid in diabetic liver. Brit. J. Nutr., 2013, 110, 401-412.
    • (2013) Brit. J. Nutr , vol.110 , pp. 401-412
    • Dinić, S.1    Arambašić, J.2    Mihailović, M.3    Uskoković, A.4    Grdović, N.5    Marković, J.6    Karadžić, B.7    Poznanović, G.8    Vidaković, M.9
  • 28
    • 84856093034 scopus 로고    scopus 로고
    • Alpha-lipoic acid attenuates methionine choline deficient diet-induced steatohepatitis in C57BL/6 mice
    • Min, A.-K.; Kim, M.-K.; Kim, H.-S.; Seo, H.-Y.; Lee, K.-U.; Kim, J.-G.; Park, K.; Lee, I.-K. Alpha-lipoic acid attenuates methionine choline deficient diet-induced steatohepatitis in C57BL/6 mice. Life Sci., 2012, 90, 200-205.
    • (2012) Life Sci , vol.90 , pp. 200-205
    • Min, A.-K.1    Kim, M.-K.2    Kim, H.-S.3    Seo, H.-Y.4    Lee, K.-U.5    Kim, J.-G.6    Park, K.7    Lee, I.-K.8
  • 29
    • 84876571372 scopus 로고    scopus 로고
    • The protective effect of alphalipoic Acid in lipopolysaccharide-induced acute lung injury is mediated by heme oxygenase-1. Evid. Based. Complement
    • Lin, Y.-C.; Lai, Y.-S.; Chou, T.-C. The protective effect of alphalipoic Acid in lipopolysaccharide-induced acute lung injury is mediated by heme oxygenase-1. Evid. Based. Complement. Alternat. Med., 2013, 2013, 590363.
    • (2013) Alternat. Med , vol.2013
    • Lin, Y.-C.1    Lai, Y.-S.2    Chou, T.-C.3
  • 30
    • 84870291038 scopus 로고    scopus 로고
    • Dietary supplementation with N-acetyl cysteine, α-tocopherol and α-lipoic acid reduces the extent of oxidative stress and proinflammatory state in aged rat brain
    • Thakurta, I. G.; Chattopadhyay, M.; Ghosh, A.; Chakrabarti, S. Dietary supplementation with N-acetyl cysteine, α-tocopherol and α-lipoic acid reduces the extent of oxidative stress and proinflammatory state in aged rat brain. Biogerontology, 2012, 13, 479-488.
    • (2012) Biogerontology , vol.13 , pp. 479-488
    • Thakurta, I.G.1    Chattopadhyay, M.2    Ghosh, A.3    Chakrabarti, S.4
  • 31
    • 77951453338 scopus 로고    scopus 로고
    • Alpha-lipoic acid as a potential target for the treatment of lung injury caused by cecal ligation and puncture-induced sepsis model in rats
    • Cadirci, E.; Altunkaynak, B. Z.; Halici, Z.; Odabasoglu, F.; Uyanik, M. H.; Gundogdu, C.; Suleyman, H.; Halici, M.; Albayrak, M.; Unal, B. Alpha-lipoic acid as a potential target for the treatment of lung injury caused by cecal ligation and puncture-induced sepsis model in rats. Shock, 2010, 33, 479-484.
    • (2010) Shock , vol.33 , pp. 479-484
    • Cadirci, E.1    Altunkaynak, B.Z.2    Halici, Z.3    Odabasoglu, F.4    Uyanik, M.H.5    Gundogdu, C.6    Suleyman, H.7    Halici, M.8    Albayrak, M.9    Unal, B.10
  • 32
    • 79951726550 scopus 로고    scopus 로고
    • Evidence that α-lipoic acid inhibits NF-κB activation independent of its antioxidant function
    • Ying, Z.; Kampfrath, T.; Sun, Q.; Parthasarathy, S.; Rajagopalan, S. Evidence that α-lipoic acid inhibits NF-κB activation independent of its antioxidant function. Inflamm. Res., 2011, 60, 219-225.
    • (2011) Inflamm. Res , vol.60 , pp. 219-225
    • Ying, Z.1    Kampfrath, T.2    Sun, Q.3    Parthasarathy, S.4    Rajagopalan, S.5
  • 33
    • 84903275789 scopus 로고    scopus 로고
    • Lipoic Acid and Dihydrolipoic Acid. A Comprehensive Theoretical Study of Their Antioxidant Activity Supported by Available Experimental Kinetic Data
    • Castaneda-Arriaga R.; Alvarez-Idaboy, J. R. Lipoic Acid and Dihydrolipoic Acid. A Comprehensive Theoretical Study of Their Antioxidant Activity Supported by Available Experimental Kinetic Data. J. Chem. Inf. Model, 2014, 54, 1642-1652.
    • (2014) J. Chem. Inf. Model , vol.54 , pp. 1642-1652
    • Castaneda-Arriaga, R.1    Alvarez-Idaboy, J.R.2
  • 34
    • 27744445808 scopus 로고    scopus 로고
    • Pro-oxidant actions of alpha-lipoic acid and dihydrolipoic acid. Med
    • Cakatay, U. Pro-oxidant actions of alpha-lipoic acid and dihydrolipoic acid. Med. Hypotheses, 2006, 66, 110-117.
    • (2006) Hypotheses , vol.66 , pp. 110-117
    • Cakatay, U.1
  • 35
    • 48849114553 scopus 로고    scopus 로고
    • Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity
    • Petersen Shay, K.; Moreau, R. F.; Smith, E. J.; Hagen, T. M. Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life, 2008, 60, 362-367.
    • (2008) IUBMB Life , vol.60 , pp. 362-367
    • Petersen Shay, K.1    Moreau, R.F.2    Smith, E.J.3    Hagen, T.M.4
  • 36
    • 84879081843 scopus 로고    scopus 로고
    • Effect of oral ALA supplementation on oxidative stress and insulin sensitivity among overweight/obese adults: A double-blinded, randomized, controlled, cross-over intervention trial
    • Yan, W.; Li, N.; Hu, X.; Huang, Y.; Zhang, W.; Wang, Q.; Wang, F.; Wang, C.; Zhai, X.; Xu, R.; Yan, K.; Ding, X.; Wang, X. Effect of oral ALA supplementation on oxidative stress and insulin sensitivity among overweight/obese adults: a double-blinded, randomized, controlled, cross-over intervention trial. Int. J. Cardiol., 2013, 167, 602-603.
    • (2013) Int. J. Cardiol , vol.167 , pp. 602-603
    • Yan, W.1    Li, N.2    Hu, X.3    Huang, Y.4    Zhang, W.5    Wang, Q.6    Wang, F.7    Wang, C.8    Zhai, X.9    Xu, R.10    Yan, K.11    Ding, X.12    Wang, X.13
  • 38
    • 0031854889 scopus 로고    scopus 로고
    • Redox regulation of cell functions by alphalipoate: Biochemical and molecular aspects
    • Roy, S.; Packer, L. Redox regulation of cell functions by alphalipoate: biochemical and molecular aspects. Biofactors, 1998, 8, 17-21.
    • (1998) Biofactors , vol.8 , pp. 17-21
    • Roy, S.1    Packer, L.2
  • 39
    • 0014696016 scopus 로고
    • Clinical use of thioctic acid
    • Dabski, H. Clinical use of thioctic acid. Pol. Tyg. Lek., 1969, 24, 1502-1504.
    • (1969) Pol. Tyg. Lek , vol.24 , pp. 1502-1504
    • Dabski, H.1
  • 41
    • 0016519152 scopus 로고
    • Drug review. Thioctacid tablets. Thioctic acid-Homburg
    • Hocker, P. Drug review. Thioctacid tablets. Thioctic acid-Homburg. Med. Monatsschr., 1975, 29, 277.
    • (1975) Med. Monatsschr , vol.29 , pp. 277
    • Hocker, P.1
  • 42
    • 33644664987 scopus 로고    scopus 로고
    • Lipoic acid-the drug of the future?
    • Bilska, A.; Włodek, L. Lipoic acid-the drug of the future? Pharmacol. Rep., 2005, 57, 570-577.
    • (2005) Pharmacol. Rep , vol.57 , pp. 570-577
    • Bilska, A.1    Włodek, L.2
  • 43
    • 0024147898 scopus 로고
    • Bases and applications of the antioxidative properties of thioctic acid
    • Roldan, E. J. Bases and applications of the antioxidative properties of thioctic acid. Medicina [B. Aires]. 1988, 48, 525-529.
    • (1988) Medicina [B. Aires] , vol.48 , pp. 525-529
    • Roldan, E.J.1
  • 44
    • 0142107431 scopus 로고    scopus 로고
    • Lipoic acid: A multifunctional antioxidant
    • Bast, A.; Haenen, G. R. M. M. Lipoic acid: a multifunctional antioxidant. Biofactors, 2003, 17, 207-213.
    • (2003) Biofactors , vol.17 , pp. 207-213
    • Bast, A.1    Haenen, G.R.M.M.2
  • 46
    • 84865520840 scopus 로고    scopus 로고
    • Vascular function and the role of oxidative stress in heart failure, heart transplant, and beyond
    • Witman, M.; Fjeldstad, A.; McDaniel, J. Vascular function and the role of oxidative stress in heart failure, heart transplant, and beyond. Hypertension. 2012, 60, 659-668.
    • (2012) Hypertension , vol.60 , pp. 659-668
    • Witman, M.1    Fjeldstad, A.2    McDaniel, J.3
  • 47
    • 63449106961 scopus 로고    scopus 로고
    • Oral antioxidants and cardiovascular health in the exercise-trained and untrained elderly: A radically different outcome
    • Wray, D. W.; Uberoi, A.; Lawrenson, L.; Bailey, D. M.; Richardson, R. S. Oral antioxidants and cardiovascular health in the exercise-trained and untrained elderly: a radically different outcome. Clin. Sci. [Lond], 2009, 116, 433-441.
    • (2009) Clin. Sci. [Lond] , vol.116 , pp. 433-441
    • Wray, D.W.1    Uberoi, A.2    Lawrenson, L.3    Bailey, D.M.4    Richardson, R.S.5
  • 48
    • 81455161606 scopus 로고    scopus 로고
    • Effect of α-lipoic acid and exercise training on cardiovascular disease risk in obesity with impaired glucose tolerance
    • McNeilly, A. M.; Davison, G. W.; Murphy, M. H.; Nadeem, N.; Trinick, T.; Duly, E.; Novials, A.; McEneny, J. Effect of α-lipoic acid and exercise training on cardiovascular disease risk in obesity with impaired glucose tolerance. Lipids Health Dis., 2011, 10, 217.
    • (2011) Lipids Health Dis , vol.10 , pp. 217
    • McNeilly, A.M.1    Davison, G.W.2    Murphy, M.H.3    Nadeem, N.4    Trinick, T.5    Duly, E.6    Novials, A.7    McEneny, J.8
  • 50
    • 84894380843 scopus 로고    scopus 로고
    • Effects of combined lipoic acid and pyridoxine on albuminuria, advanced glycation end-products, and blood pressure in diabetic nephropathy
    • Noori, N.; Tabibi, H.; Hosseinpanah, F.; Hedayati, M; Nafar, M. Effects of combined lipoic acid and pyridoxine on albuminuria, advanced glycation end-products, and blood pressure in diabetic nephropathy. Int. J. Vitam. Nutr. Res., 2013, 83(2), 77-85.
    • (2013) Int. J. Vitam. Nutr. Res , vol.83 , Issue.2 , pp. 77-85
    • Noori, N.1    Tabibi, H.2    Hosseinpanah, F.3    Hedayati, M.4    Nafar, M.5
  • 51
    • 84920519500 scopus 로고    scopus 로고
    • The alpha-lipoic acid decreases urinary podocalyxin excretion in type 2 diabetics by inhibiting oxidative stress in vivo
    • Lin, H.; Ye, S.; Xu, J.; Wang, W. The alpha-lipoic acid decreases urinary podocalyxin excretion in type 2 diabetics by inhibiting oxidative stress in vivo. J. Diabetes Complications, 2015, 29(1): 64-67.
    • (2015) J. Diabetes Complications , vol.29 , Issue.1 , pp. 64-67
    • Lin, H.1    Ye, S.2    Xu, J.3    Wang, W.4
  • 52
    • 84938695483 scopus 로고    scopus 로고
    • Alleviation of podocyte injury: The possible pathway implicated in antiinflammation of alpha-lipoic acid in type 2 diabetics
    • Bao, X-H.; Xu, J; Chen, Y.; Yang, C-L.; Ye, S-D. Alleviation of podocyte injury: the possible pathway implicated in antiinflammation of alpha-lipoic acid in type 2 diabetics. Aging Clin. Exp. Res., 2014. 26 (5), 483-489.
    • (2014) Aging Clin. Exp. Res , vol.26 , Issue.5 , pp. 483-489
    • Bao, X.-H.1    Xu, J.2    Chen, Y.3    Yang, C.-L.4    Ye, S.-D.5
  • 53
    • 84896356230 scopus 로고    scopus 로고
    • Effect of the administration of alpha-lipoic acid on contrast sensitivity in patients with type 1 and type 2 diabetes
    • Gębka, A.; Serkies-Minuth, E.; Raczyńska, D. Effect of the administration of alpha-lipoic acid on contrast sensitivity in patients with type 1 and type 2 diabetes. Mediators Inflamm., 2014. 2014, 131538.
    • (2014) Mediators Inflamm , vol.2014
    • Gębka, A.1    Serkies-Minuth, E.2    Raczyńska, D.3
  • 54
    • 79955872580 scopus 로고    scopus 로고
    • The effects of lipoic acid and α-tocopherol supplementation on the lipid profile and insulin sensitivity of patients with type 2 diabetes mellitus: A randomized, double-blind, placebocontrolled trial
    • De Oliveira, A. M.; Rondo, P. H. C.; Luzia, L. A; D'Abronzo, F. H.; Illison, V. K. The effects of lipoic acid and α-tocopherol supplementation on the lipid profile and insulin sensitivity of patients with type 2 diabetes mellitus: a randomized, double-blind, placebocontrolled trial. Diabetes Res. Clin. Pract., 2011, 92, 253-260.
    • (2011) Diabetes Res. Clin. Pract , vol.92 , pp. 253-260
    • De Oliveira, A.M.1    Rondo, P.H.C.2    Luzia, L.A.3    D'Abronzo, F.H.4    Illison, V.K.5
  • 55
    • 84860343888 scopus 로고    scopus 로고
    • Glycemic and oxidative status of patients with type 2 diabetes mellitus following oral administration of alpha-lipoic acid: A randomized double-blinded placebo-controlled study
    • Porasuphatana, S.; Suddee, S.; Nartnampong, A.; Konsil, J.; Harnwong, B.; Santaweesuk, A. Glycemic and oxidative status of patients with type 2 diabetes mellitus following oral administration of alpha-lipoic acid: a randomized double-blinded placebo-controlled study. Asia Pac. J. Clin. Nutr., 2012, 21, 12-21.
    • (2012) Asia Pac. J. Clin. Nutr , vol.21 , pp. 12-21
    • Porasuphatana, S.1    Suddee, S.2    Nartnampong, A.3    Konsil, J.4    Harnwong, B.5    Santaweesuk, A.6
  • 56
    • 75149122903 scopus 로고    scopus 로고
    • Impact of therapy with α-lipoic acid (ALA) on the oxidative stress in the controlled NIDDM: A possible preventive way against the organ dysfunction?
    • Gianturco, V.; Bellomo, A.; D'ottavio, E. Impact of therapy with α-lipoic acid (ALA) on the oxidative stress in the controlled NIDDM: a possible preventive way against the organ dysfunction? Arch. Gerontol. Geriatr., 2009. 49, 129-133.
    • (2009) Arch. Gerontol. Geriatr , vol.49 , pp. 129-133
    • Gianturco, V.1    Bellomo, A.2    D'ottavio, E.3
  • 57
    • 84879967614 scopus 로고    scopus 로고
    • Effects of triple antioxidant therapy on measures of cardiovascular autonomic neuropathy and on myocardial blood flow in type 1 diabetes: A randomised controlled
    • R. Pop-Busui, R.; M. Stevens, M.; Raffel, D. Effects of triple antioxidant therapy on measures of cardiovascular autonomic neuropathy and on myocardial blood flow in type 1 diabetes: a randomised controlled. Diabetologia, 2013. 56, 1835-1844.
    • (2013) Diabetologia , vol.56 , pp. 1835-1844
    • Pop-Busui, R.R.1    Stevens, M.M.2    Raffel, D.3
  • 58
    • 84890198611 scopus 로고    scopus 로고
    • Multiple dietary supplements do not affect metabolic and cardiovascular health
    • Soare, A.; Weiss, E. P.; Holloszy, J. O.; Fontana, L. Multiple dietary supplements do not affect metabolic and cardiovascular health. Aging (Albany NY), 2013, 5, 1-9.
    • (2013) Aging (Albany NY) , vol.5 , pp. 1-9
    • Soare, A.1    Weiss, E.P.2    Holloszy, J.O.3    Fontana, L.4
  • 59
    • 69449096565 scopus 로고    scopus 로고
    • Effects of antioxidant supplements intervention on the level of plasma inflammatory molecules and disease severity of rheumatoid arthritis patients
    • Bae, S.-C.; Jung, W.-J.; Lee, E.-J.; Yu, R.; Sung, M.-K. Effects of antioxidant supplements intervention on the level of plasma inflammatory molecules and disease severity of rheumatoid arthritis patients. J. Am. Coll. Nutr., 2009, 28, 56-62.
    • (2009) J. Am. Coll. Nutr , vol.28 , pp. 56-62
    • Bae, S.-C.1    Jung, W.-J.2    Lee, E.-J.3    Yu, R.4    Sung, M.-K.5
  • 60
    • 84892940860 scopus 로고    scopus 로고
    • α-Lipoic acid and superoxide dismutase in the management of chronic neck pain: A prospective randomized study
    • Letizia Mauro, G.; Cataldo, P.; Barbera, G.; Sanfilippo, A. α-Lipoic acid and superoxide dismutase in the management of chronic neck pain: A prospective randomized study. Drugs R. D., 2014, 14, 1-7.
    • (2014) Drugs R.D , vol.14 , pp. 1-7
    • Letizia Mauro, G.1    Cataldo, P.2    Barbera, G.3    Sanfilippo, A.4
  • 61
    • 84891763377 scopus 로고    scopus 로고
    • Alpha lipoic acid and superoxide dismutase in the treatment of chronic low back pain
    • Battisti, E.; Albanese, A.; Guerra, L. Alpha lipoic acid and superoxide dismutase in the treatment of chronic low back pain. Eur. J. Phys. Rehabil. Med., 2013, 49, 659-664.
    • (2013) Eur. J. Phys. Rehabil. Med , vol.49 , pp. 659-664
    • Battisti, E.1    Albanese, A.2    Guerra, L.3
  • 62
    • 84897428034 scopus 로고    scopus 로고
    • Safety and efficacy of an add-on therapy with curcumin phytosome and piperine and/or lipoic acid in subjects with a diagnosis of peripheral neuropathy treated with dexibuprofen
    • Di Pierro, F.; Settembre, R. Safety and efficacy of an add-on therapy with curcumin phytosome and piperine and/or lipoic acid in subjects with a diagnosis of peripheral neuropathy treated with dexibuprofen. J. Pain Res., 2013, 6, 497-503.
    • (2013) J. Pain Res , vol.6 , pp. 497-503
    • Di Pierro, F.1    Settembre, R.2
  • 63
    • 84755160977 scopus 로고    scopus 로고
    • Efficacy of combined topiramate/thioctic acid therapy in migraine prophylaxis
    • Ali, A. M.; Awad, T. G.; Al-Adl, N. M. Efficacy of combined topiramate/thioctic acid therapy in migraine prophylaxis. Saudi Pharm. J., 2010, 18, 239-243.
    • (2010) Saudi Pharm. J , vol.18 , pp. 239-243
    • Ali, A.M.1    Awad, T.G.2    Al-Adl, N.M.3
  • 64
    • 84906534679 scopus 로고    scopus 로고
    • A study of the use of carbamazepine, pregabalin and alpha lipoic acid in patients of diabetic neuropathy
    • Patel, N.; Mishra, V.; Patel, P.; Dikshit, R. K. A study of the use of carbamazepine, pregabalin and alpha lipoic acid in patients of diabetic neuropathy. J. Diabetes Metab. Disord., 2014. 13(1), 62-68.
    • (2014) J. Diabetes Metab. Disord , vol.13 , Issue.1 , pp. 62-68
    • Patel, N.1    Mishra, V.2    Patel, P.3    Dikshit, R.K.4
  • 65
    • 84858691016 scopus 로고    scopus 로고
    • Combination of alpha lipoic acid and superoxide dismutase leads to physiological and symptomatic improvements in diabetic neuropathy
    • Bertolotto, F.; Massone, A. Combination of alpha lipoic acid and superoxide dismutase leads to physiological and symptomatic improvements in diabetic neuropathy. Drugs R. D., 2012, 12, 29-34.
    • (2012) Drugs R.D , vol.12 , pp. 29-34
    • Bertolotto, F.1    Massone, A.2
  • 67
    • 84871432569 scopus 로고    scopus 로고
    • Efficacy and safety of high-dose α-lipoic acid in the treatment of diabetic polyneuropathy
    • Gu, X.; Zhang, S.; Wu, J.; Tang, Z.; Lu, Z.; Li, H.; Liu, C.; Chen, L.; Ning, G. Efficacy and safety of high-dose α-lipoic acid in the treatment of diabetic polyneuropathy. Zhonghua Yi Xue Za Zhi, 2010, 90, 2473-2476.
    • (2010) Zhonghua Yi Xue Za Zhi , vol.90 , pp. 2473-2476
    • Gu, X.1    Zhang, S.2    Wu, J.3    Tang, Z.4    Lu, Z.5    Li, H.6    Liu, C.7    Chen, L.8    Ning, G.9
  • 68
    • 84893769478 scopus 로고    scopus 로고
    • Clinical usefulness of oral supplementation with alpha-lipoic Acid, curcumin phytosome, and B-group vitamins in patients with carpal tunnel syndrome undergoing surgical treatment. Evid. Based. Complement
    • Pajardi, G.; Bortot, P.; Ponti, V.; Novelli, C. Clinical usefulness of oral supplementation with alpha-lipoic Acid, curcumin phytosome, and B-group vitamins in patients with carpal tunnel syndrome undergoing surgical treatment. Evid. Based. Complement. Alternat. Med., 2014, 2014. 1-7.
    • (2014) Alternat. Med , vol.2014 , pp. 1-7
    • Pajardi, G.1    Bortot, P.2    Ponti, V.3    Novelli, C.4
  • 70
    • 73349126153 scopus 로고    scopus 로고
    • The use of alpha-lipoic acid [ALA], gamma linolenic acid [GLA] and rehabilitation in the treatment of back pain: Effect on health-related quality of life
    • Ranieri, M.; Sciuscio, M.; Cortese, A. M.; Santamato, A.; Di Teo, L.; Ianieri, G.; Bellomo, R. G.; Stasi, M.; Megna, M. The use of alpha-lipoic acid [ALA], gamma linolenic acid [GLA] and rehabilitation in the treatment of back pain: effect on health-related quality of life. Int. J. Immunopathol. Pharmacol., 2009, 22, 45-50.
    • (2009) Int. J. Immunopathol. Pharmacol , vol.22 , pp. 45-50
    • Ranieri, M.1    Sciuscio, M.2    Cortese, A.M.3    Santamato, A.4    Di Teo, L.5    Ianieri, G.6    Bellomo, R.G.7    Stasi, M.8    Megna, M.9
  • 73
    • 84887224886 scopus 로고    scopus 로고
    • A randomized placebo-controlled pilot trial of omega-3 fatty acids and alpha lipoic acid in Alzheimer's disease
    • Shinto, L.; Quinn, J.; Montine, T. A randomized placebo-controlled pilot trial of omega-3 fatty acids and alpha lipoic acid in Alzheimer's disease. J. Alzheimer's Dis., 2014, 38, 1-16.
    • (2014) J. Alzheimer's Dis , vol.38 , pp. 1-16
    • Shinto, L.1    Quinn, J.2    Montine, T.3
  • 75
    • 84899621648 scopus 로고    scopus 로고
    • The effect of lipoate on anaerobic cysteine metabolism in erythrocytes of patients treated with peritoneal dialysis
    • Iciek, M.; Marcykiewicz, B.; Bilska-Wilkosz, A.; Sokołowska-Jeżewicz, M.; Kłapcińska, J. The effect of lipoate on anaerobic cysteine metabolism in erythrocytes of patients treated with peritoneal dialysis. Pharmacol. Rep., 2014, 66, 325-328.
    • (2014) Pharmacol. Rep , vol.66 , pp. 325-328
    • Iciek, M.1    Marcykiewicz, B.2    Bilska-Wilkosz, A.3    Sokołowska-Jeżewicz, M.4    Kłapcińska, J.5
  • 76
    • 84930902000 scopus 로고    scopus 로고
    • Effect of α-lipoic acid on oxidative stress in end-stage renal disease patients receiving intravenous iron
    • Showkat, A.; Bastnagel, W. R.; Hudson, J. Q. Effect of α-lipoic acid on oxidative stress in end-stage renal disease patients receiving intravenous iron. ISRN Nephrol., 2014, 2014, 634515.
    • (2014) ISRN Nephrol , vol.2014
    • Showkat, A.1    Bastnagel, W.R.2    Hudson, J.Q.3
  • 77
    • 84906737741 scopus 로고    scopus 로고
    • Effects of alpha-lipoic acid supplementation on serum levels of IL-8 and TNF-α in patient with ESRD undergoing hemodialysis
    • Safa, J.; Ardalan, M. R.; Rezazadehsaatlou, M.; Mesgari, M.; Mahdavi, R.; Jadid, M. P. Effects of alpha-lipoic acid supplementation on serum levels of IL-8 and TNF-α in patient with ESRD undergoing hemodialysis. Int. Urol. Nephrol., 2014, 46, 1633-1638.
    • (2014) Int. Urol. Nephrol , vol.46 , pp. 1633-1638
    • Safa, J.1    Ardalan, M.R.2    Rezazadehsaatlou, M.3    Mesgari, M.4    Mahdavi, R.5    Jadid, M.P.6
  • 78
    • 84887851274 scopus 로고    scopus 로고
    • Effect of alpha-lipoic cid and vitamin E supplementation on oxidative stress, inflammation, and malnutrition in hemodialysis patients
    • Ahmadi, A.; Mazooji, N. Effect of alpha-lipoic cid and vitamin E supplementation on oxidative stress, inflammation, and malnutrition in hemodialysis patients. Iran. J. Kidney Dis., 2013. 7, 461-467.
    • (2013) Iran. J. Kidney Dis , vol.7 , pp. 461-467
    • Ahmadi, A.1    Mazooji, N.2
  • 79
    • 84883650980 scopus 로고    scopus 로고
    • Role of alpha-lipoic acid in the management of anemia in patients with chronic renal failure undergoing hemodialysis
    • El-Nakib, G.; Mostafa, T. Role of alpha-lipoic acid in the management of anemia in patients with chronic renal failure undergoing hemodialysis. Int. J. Nephrol. Renovasc. Dis., 2013, 6, 161-168.
    • (2013) Int. J. Nephrol. Renovasc. Dis , vol.6 , pp. 161-168
    • El-Nakib, G.1    Mostafa, T.2
  • 80
    • 84857373556 scopus 로고    scopus 로고
    • Effects of alpha-lipoic acid supplementation on inflammation, oxidative stress, and serum lipid profile levels in patients with end-stage renal disease on hemodialysis
    • Khabbazi, T.; Mahdavi, R.; Safa, J.; Pour-Abdollahi, P. Effects of alpha-lipoic acid supplementation on inflammation, oxidative stress, and serum lipid profile levels in patients with end-stage renal disease on hemodialysis. J. Ren. Nutr., 2012, 22, 244-250.
    • (2012) J. Ren. Nutr , vol.22 , pp. 244-250
    • Khabbazi, T.1    Mahdavi, R.2    Safa, J.3    Pour-Abdollahi, P.4
  • 81
    • 79955107348 scopus 로고    scopus 로고
    • Effects of combination tocopherols and alpha lipoic acid therapy on oxidative stress and inflammatory biomarkers in chronic kidney disease
    • Ramos, L. F.; Kane, J.; McMonagle, E.; Le, P.; Wu, P.; Shintani, A.; Ikizler, T. A.; Himmelfarb, J. Effects of combination tocopherols and alpha lipoic acid therapy on oxidative stress and inflammatory biomarkers in chronic kidney disease. J. Ren. Nutr., 2011, 21, 211-218.
    • (2011) J. Ren. Nutr , vol.21 , pp. 211-218
    • Ramos, L.F.1    Kane, J.2    McMonagle, E.3    Le, P.4    Wu, P.5    Shintani, A.6    Ikizler, T.A.7    Himmelfarb, J.8
  • 82
    • 84931749011 scopus 로고    scopus 로고
    • The combination of α-lipoic acid intake with eccentric exercise modulates erythropoietin release
    • Morawin, B.; Turowski, D.; Naczk, M.; Siatkowski, I.; Zembron-Lacny, A. The combination of α-lipoic acid intake with eccentric exercise modulates erythropoietin release. Biol. Sport., 2014, 31, 179-185.
    • (2014) Biol. Sport , vol.31 , pp. 179-185
    • Morawin, B.1    Turowski, D.2    Naczk, M.3    Siatkowski, I.4    Zembron-Lacny, A.5
  • 83
    • 84908223229 scopus 로고    scopus 로고
    • Effects of aspirin and simvastatin and aspirin, simvastatin, and lipoic acid on heme oxygenase-1 in healthy human subjects
    • Bharucha, A. E.; Choi, K. M.; Saw, J. J.; Gibbons, S. J.; Farrugia, G. F.; Carlson, D.; Zinsmeister, A. R. Effects of aspirin and simvastatin and aspirin, simvastatin, and lipoic acid on heme oxygenase-1 in healthy human subjects. Neurogastroenterol. Motil., 2014, 26, 1437-1442.
    • (2014) Neurogastroenterol. Motil , vol.26 , pp. 1437-1442
    • Bharucha, A.E.1    Choi, K.M.2    Saw, J.J.3    Gibbons, S.J.4    Farrugia, G.F.5    Carlson, D.6    Zinsmeister, A.R.7
  • 84
    • 84892970235 scopus 로고    scopus 로고
    • The role of prostaglandin and antioxidant availability in recovery from forearm ischemia-reperfusion injury in humans
    • Carter, S. E.; Faulkner, A.; Rakobowchuk, M. The role of prostaglandin and antioxidant availability in recovery from forearm ischemia-reperfusion injury in humans. J. Hypertens., 2014, 32, 339-51.
    • (2014) J. Hypertens , vol.32 , pp. 339-351
    • Carter, S.E.1    Faulkner, A.2    Rakobowchuk, M.3
  • 86
    • 84861796305 scopus 로고    scopus 로고
    • Effect of [R]-α-lipoic acid supplementation on serum lipids and antioxidative ability in patients with age-related macular degeneration
    • Sun, Y.-D.; Dong, Y.-D.; Fan, R.; Zhai, L.-L.; Bai, Y.-L.; Jia, L.-H. Effect of [R]-α-lipoic acid supplementation on serum lipids and antioxidative ability in patients with age-related macular degeneration. Ann. Nutr. Metab., 2012, 60, 293-297.
    • (2012) Ann. Nutr. Metab , vol.60 , pp. 293-297
    • Sun, Y.-D.1    Dong, Y.-D.2    Fan, R.3    Zhai, L.-L.4    Bai, Y.-L.5    Jia, L.-H.6
  • 87
    • 84872712841 scopus 로고    scopus 로고
    • Oral supplementation with antioxidant agents containing alpha lipoic acid: Effects on postmenopausal bone mass
    • Mainini, G.; Rotondi, M. Oral supplementation with antioxidant agents containing alpha lipoic acid: effects on postmenopausal bone mass. Clin Exp Obs. Gynecol., 2012, 39, 482-493.
    • (2012) Clin Exp Obs. Gynecol , vol.39 , pp. 482-493
    • Mainini, G.1    Rotondi, M.2
  • 88
    • 84875478434 scopus 로고    scopus 로고
    • Effects of phytoestrogen supplementation in postmenopausal women with dry eye syndrome: A randomized clinical trial
    • Scuderi, G.; Contestabile, M. T.; Gagliano, C.; Iacovello, D.; Scuderi, L.; Avitabile, T. Effects of phytoestrogen supplementation in postmenopausal women with dry eye syndrome: a randomized clinical trial. Can. J. Ophthalmol., 2012, 47, 489-492.
    • (2012) Can. J. Ophthalmol , vol.47 , pp. 489-492
    • Scuderi, G.1    Contestabile, M.T.2    Gagliano, C.3    Iacovello, D.4    Scuderi, L.5    Avitabile, T.6
  • 90
    • 74949135703 scopus 로고    scopus 로고
    • Exercise-induced brachial artery vasodilation: Effects of antioxidants and exercise training in elderly men
    • Donato, A. J.; Uberoi, A.; Bailey, D. M.; Wray, D. W.; Richardson, R. S. Exercise-induced brachial artery vasodilation: effects of antioxidants and exercise training in elderly men. Am. J. Physiol. Heart Circ. Physiol., 2010, 298, H671-H678.
    • (2010) Am. J. Physiol Heart Circ. Physiol , vol.298 , pp. H671-H678
    • Donato, A.J.1    Uberoi, A.2    Bailey, D.M.3    Wray, D.W.4    Richardson, R.S.5
  • 92
    • 84926147721 scopus 로고    scopus 로고
    • α-Tocopherol supplementation reduces biomarkers of oxidative stress in children with Down syndrome: A randomized controlled trial
    • Nachvak, S. M.; Neyestani, T. R.; Mahboob, S. A.; Sabour, S.; Keshawarz, S. A. α-Tocopherol supplementation reduces biomarkers of oxidative stress in children with Down syndrome: a randomized controlled trial. Eur. J. Clin. Nutr., 2014, 68, 1119-1123.
    • (2014) Eur. J. Clin. Nutr , vol.68 , pp. 1119-1123
    • Nachvak, S.M.1    Neyestani, T.R.2    Mahboob, S.A.3    Sabour, S.4    Keshawarz, S.A.5
  • 93
    • 79960555491 scopus 로고    scopus 로고
    • Down syndrome and dementia: A randomized, controlled trial of antioxidant supplementation
    • Lott, I. T.; Doran, E.; Nguyen, V. Q.; Tournay, A.; Head, E.; Gillen, D. L. Down syndrome and dementia: a randomized, controlled trial of antioxidant supplementation. Am. J. Med. Genet. A., 2011, 155A, 1939-1948.
    • (2011) Am. J. Med. Genet. A , vol.155 A , pp. 1939-1948
    • Lott, I.T.1    Doran, E.2    Nguyen, V.Q.3    Tournay, A.4    Head, E.5    Gillen, D.L.6
  • 94
    • 63649163373 scopus 로고    scopus 로고
    • Alpha-lipoic acid modifies oxidative stress parameters in sickle cell trait subjects and sickle cell patients
    • Martins, V. D.; Manfredini, V.; Peralba, M. C. R.; Benfato, M. S. Alpha-lipoic acid modifies oxidative stress parameters in sickle cell trait subjects and sickle cell patients. Clin. Nutr., 2009, 28, 192-197.
    • (2009) Clin. Nutr , vol.28 , pp. 192-197
    • Martins, V.D.1    Manfredini, V.2    Peralba, M.C.R.3    Benfato, M.S.4
  • 95
    • 84922005474 scopus 로고    scopus 로고
    • Alpha-Lipoic Acid Supplementation Reduces mTORC1 Signaling in Skeletal Muscle from High Fat Fed, Obese Zucker Rats
    • Li, Z.; Dungan, C. M.; Carrier, B.; Rideout, T. C.; Williamson, D. L. Alpha-Lipoic Acid Supplementation Reduces mTORC1 Signaling in Skeletal Muscle from High Fat Fed, Obese Zucker Rats. Lipids, 2014, 49, 1193-1201.
    • (2014) Lipids , vol.49 , pp. 1193-1201
    • Li, Z.1    Dungan, C.M.2    Carrier, B.3    Rideout, T.C.4    Williamson, D.L.5
  • 96
    • 84905026133 scopus 로고    scopus 로고
    • The effect of dietary α-lipoic acid, betaine, l-carnitine, and swimming on the obesity of mice induced by a high-fat diet
    • Jang, A.; Kim, D.; Sung, K.-S.; Jung, S.; Kim, H. J.; Jo, C. The effect of dietary α-lipoic acid, betaine, l-carnitine, and swimming on the obesity of mice induced by a high-fat diet. Food Funct., 2014, 5, 1966-1974.
    • (2014) Food Funct , vol.5 , pp. 1966-1974
    • Jang, A.1    Kim, D.2    Sung, K.-S.3    Jung, S.4    Kim, H.J.5    Jo, C.6
  • 97
  • 98
    • 84885036188 scopus 로고    scopus 로고
    • α-lipoic acid attenuates obesity-associated hippocampal neuroinflammation and increases the levels of brain-derived neurotrophic factor in ovariectomized rats fed a high-fat
    • Miao, Y.; Ren, J.; Jiang, L.; Liu, J.; Jiang, B.; Zhang, X. α-lipoic acid attenuates obesity-associated hippocampal neuroinflammation and increases the levels of brain-derived neurotrophic factor in ovariectomized rats fed a high-fat. Int. J. Mol. Med., 2013, 5, 1179-1186.
    • (2013) Int. J. Mol. Med , vol.5 , pp. 1179-1186
    • Miao, Y.1    Ren, J.2    Jiang, L.3    Liu, J.4    Jiang, B.5    Zhang, X.6
  • 100
    • 84864194149 scopus 로고    scopus 로고
    • α-Lipoic acid reduced weight gain and improved the lipid profile in rats fed with high fat diet
    • Seo, E. Y.; Ha, A. W.; Kim, W. K. α-Lipoic acid reduced weight gain and improved the lipid profile in rats fed with high fat diet. Nutr. Res. Pract., 2012, 6, 195-200.
    • (2012) Nutr. Res. Pract , vol.6 , pp. 195-200
    • Seo, E.Y.1    Ha, A.W.2    Kim, W.K.3
  • 101
    • 84868244210 scopus 로고    scopus 로고
    • Flaxseed oil and α-lipoic acid combination reduces atherosclerosis risk factors in rats fed a high-fat diet
    • Xu, J.; Yang, W.; Deng, Q.; Huang, Q.; Yang, J.; Huang, F. Flaxseed oil and α-lipoic acid combination reduces atherosclerosis risk factors in rats fed a high-fat diet. Lipids Health Dis., 2012, 11, 148.
    • (2012) Lipids Health Dis , vol.11 , pp. 148
    • Xu, J.1    Yang, W.2    Deng, Q.3    Huang, Q.4    Yang, J.5    Huang, F.6
  • 102
    • 84884588027 scopus 로고    scopus 로고
    • Reversal of obesityinduced hypertriglyceridemia by [R]-α-lipoic acid in ZDF [fa/fa] rats
    • Yi, X.; Pashaj, A.; Xia, M.; Moreau, R. Reversal of obesityinduced hypertriglyceridemia by [R]-α-lipoic acid in ZDF [fa/fa] rats. Biochem. Biophys. Res. Commun., 2013, 439, 390-395.
    • (2013) Biochem. Biophys. Res. Commun , vol.439 , pp. 390-395
    • Yi, X.1    Pashaj, A.2    Xia, M.3    Moreau, R.4
  • 103
    • 64549088894 scopus 로고    scopus 로고
    • Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and down regulating liver triacylglycerol secretion
    • Butler, J. A.; Hagen, T. M.; Moreau, R. Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and down regulating liver triacylglycerol secretion. Arch Biochem Biophys. 2009, 1, 485(1), 63-71.
    • (2009) Arch Biochem Biophys , vol.1-485 , Issue.1 , pp. 63-71
    • Butler, J.A.1    Hagen, T.M.2    Moreau, R.3
  • 105
    • 84927170994 scopus 로고    scopus 로고
    • Alpha-lipoic acid attenuates insulin resistance and improves glucose metabolism in high fat diet-fed mice
    • Yang, Y.; Li, W.; Liu, Y.; Li, Y.; Gao, L.; Zhao, J.-J. Alpha-lipoic acid attenuates insulin resistance and improves glucose metabolism in high fat diet-fed mice. Acta Pharmacol. Sin., 2014, 35, 1285-1292.
    • (2014) Acta Pharmacol. Sin , vol.35 , pp. 1285-1292
    • Yang, Y.1    Li, W.2    Liu, Y.3    Li, Y.4    Gao, L.5    Zhao, J.-J.6
  • 106
    • 84908556779 scopus 로고    scopus 로고
    • Antidiabetic effect of the α-lipoic acid γ-cyclodextrin complex
    • Naito, Y.; Ikuta, N.; Nakata, D. Antidiabetic effect of the α-lipoic acid γ-cyclodextrin complex. J. Clin. Biochem. Nutr., 2014, 55, 97-102.
    • (2014) J. Clin. Biochem. Nutr , vol.55 , pp. 97-102
    • Naito, Y.1    Ikuta, N.2    Nakata, D.3
  • 107
    • 84930899484 scopus 로고    scopus 로고
    • Combination therapies prevent the neuropathic, pro-inflammatory characteristics of the bone marrow in streptozotocin-induced diabetic rats
    • Dominguez, J.; Yorek, M.; Grant, M. Combination therapies prevent the neuropathic, pro-inflammatory characteristics of the bone marrow in streptozotocin-induced diabetic rats. Diabetes, 2014, 9, 1-53.
    • (2014) Diabetes , vol.9 , pp. 1-53
    • Dominguez, J.1    Yorek, M.2    Grant, M.3
  • 108
    • 84911976607 scopus 로고    scopus 로고
    • The neuroprotective benefit from pioglitazone (PIO) addition on the alpha lipoic acid (ALA)-based treatment in experimental diabetic rats
    • Jin, H. Y.; Lee, K. A.; Wu, J. Z.; Baek, H. S.; Park, T. S. The neuroprotective benefit from pioglitazone (PIO) addition on the alpha lipoic acid (ALA)-based treatment in experimental diabetic rats. Endocrine, 2014, 47, 772-782.
    • (2014) Endocrine , vol.47 , pp. 772-782
    • Jin, H.Y.1    Lee, K.A.2    Wu, J.Z.3    Baek, H.S.4    Park, T.S.5
  • 109
    • 84896723232 scopus 로고    scopus 로고
    • Beneficial effects of the nutritional supplements on the development of diabetic retinopathy
    • Kowluru, R. A.; Zhong, Q.; Santos, J. M.; Thandampallayam, M.; Putt, D.; Gierhart, D. L. Beneficial effects of the nutritional supplements on the development of diabetic retinopathy. Nutr. Metab., 2014, 11, 8-17.
    • (2014) Nutr. Metab , vol.11 , pp. 8-17
    • Kowluru, R.A.1    Zhong, Q.2    Santos, J.M.3    Thandampallayam, M.4    Putt, D.5    Gierhart, D.L.6
  • 110
    • 84881610702 scopus 로고    scopus 로고
    • Lipoic acid ameliorates apoptosis in alloxan-induced diabetic rat skeletal muscle
    • Ramasamy, S.; Sivasithamparam, N. D. Lipoic acid ameliorates apoptosis in alloxan-induced diabetic rat skeletal muscle. Biomed. Prev. Nutr., 2013, 3, 299-305.
    • (2013) Biomed. Prev. Nutr , vol.3 , pp. 299-305
    • Ramasamy, S.1    Sivasithamparam, N.D.2
  • 111
    • 84881663186 scopus 로고    scopus 로고
    • Oxidative stress in skeletal muscle impairs mitochondrial function in alloxan induced diabetic rats: Role of alpha lipoic acid
    • Saraswathi, R.; Devaraj, S. N. Oxidative stress in skeletal muscle impairs mitochondrial function in alloxan induced diabetic rats: Role of alpha lipoic acid. Biomed. Prev. Nutr., 2013, 3, 213-219.
    • (2013) Biomed. Prev. Nutr , vol.3 , pp. 213-219
    • Saraswathi, R.1    Devaraj, S.N.2
  • 112
    • 80053087465 scopus 로고    scopus 로고
    • Impact of α-lipoic acid on liver peroxisome proliferator-activated receptor-α, vascular remodeling, and oxidative stress in insulin-resistant rats
    • Midaoui, A. El; Lungu, C.; Wang, H.; Wu, L.; Robillard, C.; Deblois, D.; Couture, R. Impact of α-lipoic acid on liver peroxisome proliferator-activated receptor-α, vascular remodeling, and oxidative stress in insulin-resistant rats. Can. J. Physiol. Pharmacol., 2011, 89, 743-751.
    • (2011) Can. J. Physiol. Pharmacol , vol.89 , pp. 743-751
    • Midaoui, A.E.L.1    Lungu, C.2    Wang, H.3    Wu, L.4    Robillard, C.5    Deblois, D.6    Couture, R.7
  • 113
    • 79955065791 scopus 로고    scopus 로고
    • α-Lipoic acid protects diabetic apolipoprotein E-deficient mice from nephropathy
    • X. Yi, V. Nickeleit, L. James, and N. Maeda. α-Lipoic acid protects diabetic apolipoprotein E-deficient mice from nephropathy. J Diabetes Complications, 2011, 25, 193-201.
    • (2011) J Diabetes Complications , vol.25 , pp. 193-201
    • Yi, X.1    Nickeleit, V.2    James, L.3    Maeda, N.4
  • 114
    • 84908223860 scopus 로고    scopus 로고
    • Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway
    • Yang, Y.; Li, W.; Liu, Y.; Sun, Y.; Li, Y.; Yao, Q.; Li, J.; Zhang, Q.; Gao, Y.; Gao, L.; Zhao, J. Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway. J. Nutr. Biochem., 2014, 25, 1207-1217.
    • (2014) J. Nutr. Biochem , vol.25 , pp. 1207-1217
    • Yang, Y.1    Li, W.2    Liu, Y.3    Sun, Y.4    Li, Y.5    Yao, Q.6    Li, J.7    Zhang, Q.8    Gao, Y.9    Gao, L.10    Zhao, J.11
  • 115
    • 84886397319 scopus 로고    scopus 로고
    • Acetyl-Lcarnitine and lipoic acid improve mitochondrial abnormalities and serum levels of liver enzymes in a mouse model of nonalcoholic fatty liver disease
    • Kathirvel, E.; Morgan, K.; French, S. W.; Morgan, T. R. Acetyl-Lcarnitine and lipoic acid improve mitochondrial abnormalities and serum levels of liver enzymes in a mouse model of nonalcoholic fatty liver disease. Nutr. Res., 2013, 33, 932-941.
    • (2013) Nutr. Res , vol.33 , pp. 932-941
    • Kathirvel, E.1    Morgan, K.2    French, S.W.3    Morgan, T.R.4
  • 117
    • 84904762280 scopus 로고    scopus 로고
    • Lipoic acid entrains the hepatic circadian clock and lipid metabolic proteins that have been desynchronized with advanced age
    • Keith, D.; Finlay, L.; Butler, J.; Gomez, L.; Smith, E.; Moreau, R.; Hagen, T. Lipoic acid entrains the hepatic circadian clock and lipid metabolic proteins that have been desynchronized with advanced age. Biochem. Biophys. Res. Commun., 2014, 450, 324-329.
    • (2014) Biochem. Biophys. Res. Commun , vol.450 , pp. 324-329
    • Keith, D.1    Finlay, L.2    Butler, J.3    Gomez, L.4    Smith, E.5    Moreau, R.6    Hagen, T.7
  • 118
    • 84904039452 scopus 로고    scopus 로고
    • Effect of palladium α-lipoic acid complex on energy in the brain mitochondria of aged rats
    • Ajith, T. A.; Nima, N.; Veena, R. K.; Janardhanan, K. K.; Antonawich, F. Effect of palladium α-lipoic acid complex on energy in the brain mitochondria of aged rats. Altern. Ther. Heal. Med., 2014, 20, 27-35.
    • (2014) Altern. Ther. Heal. Med , vol.20 , pp. 27-35
    • Ajith, T.A.1    Nima, N.2    Veena, R.K.3    Janardhanan, K.K.4    Antonawich, F.5
  • 119
    • 79958094462 scopus 로고    scopus 로고
    • Age-related oxidative decline of mitochondrial functions in rat brain is prevented by long term oral antioxidant supplementation
    • Bagh, M. B.; Thakurta, I. G.; Biswas, M.; Behera, P.; Chakrabarti, S. Age-related oxidative decline of mitochondrial functions in rat brain is prevented by long term oral antioxidant supplementation. Biogerontology, 2011, 12, 119-131.
    • (2011) Biogerontology , vol.12 , pp. 119-131
    • Bagh, M.B.1    Thakurta, I.G.2    Biswas, M.3    Behera, P.4    Chakrabarti, S.5
  • 120
    • 77956184321 scopus 로고    scopus 로고
    • Aging and antioxidants modulate rat brain levels of homocysteine and dehydroepiandrosterone sulphate [DHEA-S]: Implications in the pathogenesis of Alzheimer's disease
    • Sinha, M.; Saha, A.; Basu, S.; Pal, K.; Chakrabarti, S. Aging and antioxidants modulate rat brain levels of homocysteine and dehydroepiandrosterone sulphate [DHEA-S]: implications in the pathogenesis of Alzheimer's disease. Neurosci. Lett., 2010, 483, 123-126.
    • (2010) Neurosci. Lett , vol.483 , pp. 123-126
    • Sinha, M.1    Saha, A.2    Basu, S.3    Pal, K.4    Chakrabarti, S.5
  • 121
    • 77952833239 scopus 로고    scopus 로고
    • Alpha-Lipoic acid increases energy expenditure by enhancing adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling in the skeletal muscle of aged mice
    • Wang, Y.; Li, X.; Guo, Y.; Chan, L.; Guan, X. Alpha-Lipoic acid increases energy expenditure by enhancing adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling in the skeletal muscle of aged mice. Metabolism, 2010, 59, 967-976.
    • (2010) Metabolism , vol.59 , pp. 967-976
    • Wang, Y.1    Li, X.2    Guo, Y.3    Chan, L.4    Guan, X.5
  • 122
    • 77953535381 scopus 로고    scopus 로고
    • Effect of POLY-MVA, a palladium alpha-lipoic acid complex formulation against declined mitochondrial antioxidant status in the myocardium of aged rats
    • Sudheesh, N. P.; Ajith, T. a; Janardhanan, K. K.; Krishnan, C. V. Effect of POLY-MVA, a palladium alpha-lipoic acid complex formulation against declined mitochondrial antioxidant status in the myocardium of aged rats. Food Chem. Toxicol., 2010, 48, 1858-1862.
    • (2010) Food Chem. Toxicol , vol.48 , pp. 1858-1862
    • Sudheesh, N.P.1    Ajith, T.2    Janardhanan, K.K.3    Krishnan, C.V.4
  • 124
    • 68649119963 scopus 로고    scopus 로고
    • Palladium alpha-lipoic acid complex formulation enhances activities of Krebs cycle dehydrogenases and respiratory complexes I-IV in the heart of aged rats
    • Sudheesh, N. P.; Ajith, T. a; Janardhanan, K. K.; Krishnan, C. V. Palladium alpha-lipoic acid complex formulation enhances activities of Krebs cycle dehydrogenases and respiratory complexes I-IV in the heart of aged rats. Food Chem. Toxicol., 2009, 47, 2124-2128.
    • (2009) Food Chem. Toxicol , vol.47 , pp. 2124-2128
    • Sudheesh, N.P.1    Ajith, T.2    Janardhanan, K.K.3    Krishnan, C.V.4
  • 125
    • 84922219033 scopus 로고    scopus 로고
    • Hypermetabolic state in the 7-month-old triple transgenic mouse model of Alzheimer's disease and the effect of lipoic acid: A (13)C-NMR study
    • Sancheti, H.; Patil, I.; Kanamori, K.; Diaz Brinton, R.; Zhang, W.; Lin, A.-L.; Cadenas, E. Hypermetabolic state in the 7-month-old triple transgenic mouse model of Alzheimer's disease and the effect of lipoic acid: a (13)C-NMR study. J. Cereb. Blood Flow Metab., 2014, 34(11), 1749-60.
    • (2014) J. Cereb. Blood Flow Metab , vol.34 , Issue.11 , pp. 1749-1760
    • Sancheti, H.1    Patil, I.2    Kanamori, K.3    Diaz Brinton, R.4    Zhang, W.5    Lin, A.-L.6    Cadenas, E.7
  • 127
    • 84864634038 scopus 로고    scopus 로고
    • High-fat diets impair spatial learning of mice in the Y-maze paradigm: Ameliorative potential of α-lipoic acid
    • Cui, Y.; Shu, Y.; Zhu, Y.; Shi, Y.; Le, G. High-fat diets impair spatial learning of mice in the Y-maze paradigm: ameliorative potential of α-lipoic acid. J. Med. Food, 2012, 15, 713-717.
    • (2012) J. Med. Food , vol.15 , pp. 713-717
    • Cui, Y.1    Shu, Y.2    Zhu, Y.3    Shi, Y.4    Le, G.5
  • 129
    • 84879066709 scopus 로고    scopus 로고
    • Nutraceutical agents with anti-inflammatory properties prevent dietary saturated-fat induced disturbances in blood-brain barrier function in wild-type mice
    • Takechi, R.; Pallebage-Gamarallage, M. M.; Lam, V.; Giles, C.; Mamo, J. C. Nutraceutical agents with anti-inflammatory properties prevent dietary saturated-fat induced disturbances in blood-brain barrier function in wild-type mice. J. Neuroinflammation, 2013, 19, 73-84.
    • (2013) J. Neuroinflammation , vol.19 , pp. 73-84
    • Takechi, R.1    Pallebage-Gamarallage, M.M.2    Lam, V.3    Giles, C.4    Mamo, J.C.5
  • 130
    • 81055140360 scopus 로고    scopus 로고
    • Intervention of mitochondrial dysfunction-oxidative stress-dependent apoptosis as a possible neuroprotective mechanism of α-lipoic acid against rotenone-induced parkinsonism and L-dopa toxicity
    • Abdin, A. a; Sarhan, N. I. Intervention of mitochondrial dysfunction-oxidative stress-dependent apoptosis as a possible neuroprotective mechanism of α-lipoic acid against rotenone-induced parkinsonism and L-dopa toxicity. Neurosci. Res., 2011, 71, 387-395.
    • (2011) Neurosci. Res , vol.71 , pp. 387-395
    • Abdin, A.1    Sarhan, N.I.2
  • 131
    • 58649103550 scopus 로고    scopus 로고
    • Dietary supplementation with a combination of alpha-lipoic acid, acetyl-L-carnitine, glycerophosphocoline, docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance
    • Suchy, J.; Chan, A.; Shea, T. B. Dietary supplementation with a combination of alpha-lipoic acid, acetyl-L-carnitine, glycerophosphocoline, docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance. Nutr. Res., 2009, 29, 70-74.
    • (2009) Nutr. Res , vol.29 , pp. 70-74
    • Suchy, J.1    Chan, A.2    Shea, T.B.3
  • 132
    • 67651171225 scopus 로고    scopus 로고
    • Effect of alpha lipoic acid on the tardive dyskinesia and oxidative stress induced by haloperidol in rats
    • Thaakur, S.; Himabindhu, G. Effect of alpha lipoic acid on the tardive dyskinesia and oxidative stress induced by haloperidol in rats. J. Neural Transm., 2009, 116, 807-814.
    • (2009) J. Neural Transm , vol.116 , pp. 807-814
    • Thaakur, S.1    Himabindhu, G.2
  • 133
    • 76849084850 scopus 로고    scopus 로고
    • Alpha lipoic acid alleviates oxidative stress and preserves blood brain permeability in rats with subarachnoid hemorrhage
    • Erşahin, M.; Toklu, H. Z.; Cetinel, S.; Yuksel, M.; Erzik, C.; Berkman, M. Z.; Yeğen, B. C.; Sener, G. Alpha lipoic acid alleviates oxidative stress and preserves blood brain permeability in rats with subarachnoid hemorrhage. Neurochem. Res., 2010, 35, 418-428.
    • (2010) Neurochem. Res , vol.35 , pp. 418-428
    • Erşahin, M.1    Toklu, H.Z.2    Cetinel, S.3    Yuksel, M.4    Erzik, C.5    Berkman, M.Z.6    Yeğen, B.C.7    Sener, G.8
  • 134
    • 84887565465 scopus 로고    scopus 로고
    • Ochratoxin A induces karyomegaly and cell cycle aberrations in renal tubular cells without relation to induction of oxidative stress responses in rats
    • Taniai, E.; Yafune, A.; Nakajima, M.; Hayashi, S.-M.; Nakane, F.; Itahashi, M.; Shibutani, M. Ochratoxin A induces karyomegaly and cell cycle aberrations in renal tubular cells without relation to induction of oxidative stress responses in rats. Toxicol. Lett., 2014, 224, 64-72.
    • (2014) Toxicol. Lett , vol.224 , pp. 64-72
    • Taniai, E.1    Yafune, A.2    Nakajima, M.3    Hayashi, S.-M.4    Nakane, F.5    Itahashi, M.6    Shibutani, M.7
  • 136
    • 84884680201 scopus 로고    scopus 로고
    • Inhibitory effect of α-lipoic acid on thioacetamide-induced tumor promotion through suppression of inflammatory cell responses in a two-stage hepatocarcinogenesis model in rats
    • Fujii, Y.; Segawa, R.; Kimura, M.; Wang, L.; Ishii, Y.; Yamamoto, R.; Morita, R.; Mitsumori, K.; Shibutani, M. Inhibitory effect of α-lipoic acid on thioacetamide-induced tumor promotion through suppression of inflammatory cell responses in a two-stage hepatocarcinogenesis model in rats. Chem. Biol. Interact., 2013, 205, 108-118.
    • (2013) Chem. Biol. Interact , vol.205 , pp. 108-118
    • Fujii, Y.1    Segawa, R.2    Kimura, M.3    Wang, L.4    Ishii, Y.5    Yamamoto, R.6    Morita, R.7    Mitsumori, K.8    Shibutani, M.9
  • 137
    • 84862332140 scopus 로고    scopus 로고
    • Alfa-lipoic acid controls tumor growth and modulates hepatic redox state in Ehrlich-ascites-carcinoma-bearing mice
    • Al Abdan, M. Alfa-lipoic acid controls tumor growth and modulates hepatic redox state in Ehrlich-ascites-carcinoma-bearing mice. ScientificWorldJournal, 2012, 2012, 509838.
    • (2012) ScientificWorldJournal , vol.2012
    • Al Abdan, M.1
  • 138
    • 84880339863 scopus 로고    scopus 로고
    • Role of α-lipoic acid in dextran sulfate sodium-induced ulcerative colitis in mice: Studies on inflammation, oxidative stress, DNA damage and fibrosis
    • Trivedi, P. P.; Jena, G. B. Role of α-lipoic acid in dextran sulfate sodium-induced ulcerative colitis in mice: studies on inflammation, oxidative stress, DNA damage and fibrosis. Food Chem. Toxicol., 2013, 59, 339-355.
    • (2013) Food Chem. Toxicol , vol.59 , pp. 339-355
    • Trivedi, P.P.1    Jena, G.B.2
  • 139
    • 84863080188 scopus 로고    scopus 로고
    • Lipoic acid attenuates high-fat-diet-induced oxidative stress and B-cell-related immune depression
    • Cui, J.; Xiao, Y.; Shi, Y.-H.; Wang, B.; Le, G.-W. Lipoic acid attenuates high-fat-diet-induced oxidative stress and B-cell-related immune depression. Nutrition, 2012, 28, 275-280.
    • (2012) Nutrition , vol.28 , pp. 275-280
    • Cui, J.1    Xiao, Y.2    Shi, Y.-H.3    Wang, B.4    Le, G.-W.5
  • 141
    • 84893567123 scopus 로고    scopus 로고
    • Reloading functionally ameliorates disuse-induced muscle atrophy by reversing mitochondrial dysfunction, and similar benefits are gained by administering a combination of mitochondrial nutrients
    • Liu, J.; Peng, Y.; Feng, Z.; Shi, W.; Qu, L.; Li, Y.; Liu, J.; Long, J. Reloading functionally ameliorates disuse-induced muscle atrophy by reversing mitochondrial dysfunction, and similar benefits are gained by administering a combination of mitochondrial nutrients. Free Radic. Biol. Med., 2014, 69, 116-128.
    • (2014) Free Radic. Biol. Med , vol.69 , pp. 116-128
    • Liu, J.1    Peng, Y.2    Feng, Z.3    Shi, W.4    Qu, L.5    Li, Y.6    Liu, J.7    Long, J.8
  • 142
    • 84898998233 scopus 로고    scopus 로고
    • Modulatory effects of curcumin, silybin-phytosome and alpha-R-lipoic acid against thioacetamide-induced liver cirrhosis in rats
    • Ali, S. O.; Darwish, H. A. E.; Ismail, N. A. E. Modulatory effects of curcumin, silybin-phytosome and alpha-R-lipoic acid against thioacetamide-induced liver cirrhosis in rats. Chem. Biol. Interact., 2014, 216, 26-33.
    • (2014) Chem. Biol. Interact , vol.216 , pp. 26-33
    • Ali, S.O.1    Darwish, H.A.E.2    Ismail, N.A.E.3
  • 143
    • 84922449490 scopus 로고    scopus 로고
    • Prophylactic role of α-lipoic acid and vitamin E against zinc oxide nanoparticles induced metabolic and immune disorders in rat's liver
    • Al-Rasheed, N. M.; Baky, N. A. A.; Faddah, L. M.; Fatani, A. J.; Hasan, I. H.; Mohamad, R. A. Prophylactic role of α-lipoic acid and vitamin E against zinc oxide nanoparticles induced metabolic and immune disorders in rat's liver. Eur. Rev. Med. Pharmacol. Sci., 2014, 18, 1813-1828.
    • (2014) Eur. Rev. Med. Pharmacol. Sci , vol.18 , pp. 1813-1828
    • Al-Rasheed, N.M.1    Baky, N.A.A.2    Faddah, L.M.3    Fatani, A.J.4    Hasan, I.H.5    Mohamad, R.A.6
  • 144
    • 84988851432 scopus 로고    scopus 로고
    • Oral antioxidant therapy for juvenile rats with kaolin-induced hydrocephalus
    • Di Curzio, D. L.; Turner-Brannen, E.; Del Bigio, M. R. Oral antioxidant therapy for juvenile rats with kaolin-induced hydrocephalus. Fluids Barriers CNS. 2014, 11, 23-33.
    • (2014) Fluids Barriers CNS , vol.11 , pp. 23-33
    • Di Curzio, D.L.1    Turner-Brannen, E.2    Del Bigio, M.R.3
  • 145
    • 84930886754 scopus 로고    scopus 로고
    • Effects of lipoic Acid on acrylamide induced testicular damage
    • Lebda, M.; Gad, S.; Gaafar, H. Effects of lipoic Acid on acrylamide induced testicular damage. Mater. Sociomed., 2014, 26, 208-212.
    • (2014) Mater. Sociomed , vol.26 , pp. 208-212
    • Lebda, M.1    Gad, S.2    Gaafar, H.3
  • 147
    • 84929512608 scopus 로고    scopus 로고
    • Alphalipoic acid and N-acetylcysteine protects intensive swimming exercise-mediated germ-cell depletion, pro-oxidant generation, and alteration of steroidogenesis in rat testis
    • Jana, K.; Dutta, A.; Chakraborty, P.; Manna, I.; Firdaus, S. B.; Bandyopadhyay, D.; Chattopadhyay, R.; Chakravarty, B. Alphalipoic acid and N-acetylcysteine protects intensive swimming exercise-mediated germ-cell depletion, pro-oxidant generation, and alteration of steroidogenesis in rat testis. Mol. Reprod. Dev., 2014, 81, 833-850.
    • (2014) Mol. Reprod. Dev , vol.81 , pp. 833-850
    • Jana, K.1    Dutta, A.2    Chakraborty, P.3    Manna, I.4    Firdaus, S.B.5    Bandyopadhyay, D.6    Chattopadhyay, R.7    Chakravarty, B.8
  • 148
    • 84891545452 scopus 로고    scopus 로고
    • Dietary α-lipoic acid prevents UVB-induced corneal and conjunctival degeneration through multiple effects. Invest. Ophthalmol
    • Chen, B.-Y.; Lin, D. P.-C.; Chang, L.-S.; Huang, T.-P.; Liu, H.-J.; Luk, C.-P.; Lo, Y.-L.; Chang, H.-H. Dietary α-lipoic acid prevents UVB-induced corneal and conjunctival degeneration through multiple effects. Invest. Ophthalmol. Vis. Sci., 2013, 54, 6757-6766.
    • (2013) Vis. Sci , vol.54 , pp. 6757-6766
    • Chen, B.-Y.1    Lin, D.P.-C.2    Chang, L.-S.3    Huang, T.-P.4    Liu, H.-J.5    Luk, C.-P.6    Lo, Y.-L.7    Chang, H.-H.8
  • 150
    • 84898044840 scopus 로고    scopus 로고
    • Efficacy of some antioxidants supplementation in reducing oxidative stress post sodium tungstate exposure in male wistar rats
    • Sachdeva, S.; Flora, S. J. S. Efficacy of some antioxidants supplementation in reducing oxidative stress post sodium tungstate exposure in male wistar rats. J. Trace Elem. Med. Biol., 2014, 28, 233-239.
    • (2014) J. Trace Elem. Med. Biol , vol.28 , pp. 233-239
    • Sachdeva, S.1    Flora, S.J.S.2
  • 151
    • 79960230507 scopus 로고    scopus 로고
    • The effect of alpha-lipoic acid in the prevention of peritoneal adhesions
    • Ozler, M.; Ersoz, N.; Ozerhan, H.; Topal, T.; Korkmaz, A. The effect of alpha-lipoic acid in the prevention of peritoneal adhesions. Turk. J. Gastroenterol., 2011, 22, 190-194.
    • (2011) Turk. J. Gastroenterol , vol.22 , pp. 190-194
    • Ozler, M.1    Ersoz, N.2    Ozerhan, H.3    Topal, T.4    Korkmaz, A.5
  • 152
    • 84888407191 scopus 로고    scopus 로고
    • Alpha-lipoic acid protects oxidative stress, changes in cholinergic system and tissue histopathology during co-exposure to arsenic-dichlorvos in rats
    • Dwivedi, N.; Flora, G.; Kushwaha, P.; Flora, S. J. S. Alpha-lipoic acid protects oxidative stress, changes in cholinergic system and tissue histopathology during co-exposure to arsenic-dichlorvos in rats. Environ. Toxicol. Pharmacol., 2013, 37, 7-23.
    • (2013) Environ. Toxicol. Pharmacol , vol.37 , pp. 7-23
    • Dwivedi, N.1    Flora, G.2    Kushwaha, P.3    Flora, S.J.S.4
  • 153
    • 57249095883 scopus 로고    scopus 로고
    • Effect of alpha-lipoic acid on visual evoked potentials in rats exposed to sulfite
    • Derin, N.; Akpinar, D.; Yargicoglu, P.; Agar, A.; Aslan, M. Effect of alpha-lipoic acid on visual evoked potentials in rats exposed to sulfite. Neurotoxicol. Teratol., 2009, 31, 34-39.
    • (2009) Neurotoxicol. Teratol , vol.31 , pp. 34-39
    • Derin, N.1    Akpinar, D.2    Yargicoglu, P.3    Agar, A.4    Aslan, M.5
  • 154
    • 77957759556 scopus 로고    scopus 로고
    • Effects of duodenal redox status on calcium absorption and related genes expression in high-fat diet-fed mice
    • Xiao, Y.; Cui, J.; Shi, Y.-H.; Sun, J.; Wang, Z.-P.; Le, G.-W. Effects of duodenal redox status on calcium absorption and related genes expression in high-fat diet-fed mice. Nutrition, 2010, 26, 1188-1194.
    • (2010) Nutrition , vol.26 , pp. 1188-1194
    • Xiao, Y.1    Cui, J.2    Shi, Y.-H.3    Sun, J.4    Wang, Z.-P.5    Le, G.-W.6
  • 155
    • 79955446717 scopus 로고    scopus 로고
    • Lipoic acid increases the expression of genes involved in bone formation in mice fed a high-fat diet
    • Xiao, Y.; Cui, J.; Shi, Y.; Le, G. Lipoic acid increases the expression of genes involved in bone formation in mice fed a high-fat diet. Nutr. Res., 2011, 31, 309-317.
    • (2011) Nutr. Res , vol.31 , pp. 309-317
    • Xiao, Y.1    Cui, J.2    Shi, Y.3    Le, G.4
  • 157
    • 84878766975 scopus 로고    scopus 로고
    • α-Lipoic acid antioxidant treatment limits glaucoma-related retinal ganglion cell death and dysfunction
    • Inman, D. M.; Lambert, W. S.; Calkins, D. J.; Horner, P. J. α-Lipoic acid antioxidant treatment limits glaucoma-related retinal ganglion cell death and dysfunction. PLoS One, 2013, 8, e65389.
    • (2013) PLoS One , vol.8
    • Inman, D.M.1    Lambert, W.S.2    Calkins, D.J.3    Horner, P.J.4
  • 159
    • 84875812556 scopus 로고    scopus 로고
    • Attenuation of uremia by orally feeding alpha-lipoic acid on acetaminophen induced uremic rats
    • Pradhan, S.; Mandal, S.; Roy, S.; Mandal, A.; Das, K.; Nandi, D. K. Attenuation of uremia by orally feeding alpha-lipoic acid on acetaminophen induced uremic rats. Saudi Pharm J., 2013, 21, 187-192.
    • (2013) Saudi Pharm J , vol.21 , pp. 187-192
    • Pradhan, S.1    Mandal, S.2    Roy, S.3    Mandal, A.4    Das, K.5    Nandi, D.K.6
  • 160
    • 77950255849 scopus 로고    scopus 로고
    • Antioxidant diet supplementation starting 24 hours after exposure reduces radiation lethality
    • Brown, S.; Kolozsvary, A.; Liu, J.; Jenrow, K. Antioxidant diet supplementation starting 24 hours after exposure reduces radiation lethality. Radiat Res., 2013, 173, 462-468.
    • (2013) Radiat Res , vol.173 , pp. 462-468
    • Brown, S.1    Kolozsvary, A.2    Liu, J.3    Jenrow, K.4
  • 161
    • 84893178317 scopus 로고    scopus 로고
    • Protective effect of alpha-lipoic acid on cypermethrin-induced oxidative stress in Wistar rats
    • Mignini, F.; Nasuti, C.; Fedeli, D. Protective effect of alpha-lipoic acid on cypermethrin-induced oxidative stress in Wistar rats. Int. J. Immunopathol. Pharmacol., 2013, 26, 871-881.
    • (2013) Int. J. Immunopathol. Pharmacol , vol.26 , pp. 871-881
    • Mignini, F.1    Nasuti, C.2    Fedeli, D.3
  • 162
    • 84866016930 scopus 로고    scopus 로고
    • Therapeutic effect of alpha lipoic acid combined with praziquantel on liver fibrosis induced by Schistosoma mansoni challenged mice
    • Abdel-Hafeez, E. H.; Ahmad, A. K.; Abdulla, A. M.; Aabdel-Wahab, S.; Mosalem, F. A. Therapeutic effect of alpha lipoic acid combined with praziquantel on liver fibrosis induced by Schistosoma mansoni challenged mice. Parasitol. Res., 2012, 111, 577-586.
    • (2012) Parasitol. Res , vol.111 , pp. 577-586
    • Abdel-Hafeez, E.H.1    Ahmad, A.K.2    Abdulla, A.M.3    Aabdel-Wahab, S.4    Mosalem, F.A.5
  • 163
    • 62049083289 scopus 로고
    • Metabolic functions of thiamine and lipoic acid
    • Reed, L. J. Metabolic functions of thiamine and lipoic acid. Physiol. Rev., 1953, 33, 544-559.
    • (1953) Physiol. Rev , vol.33 , pp. 544-559
    • Reed, L.J.1
  • 164
    • 77049154710 scopus 로고
    • Effect of thioctic acid on the incorporation of carbon dioxide into pyruvate
    • Seaman, G. R. Effect of thioctic acid on the incorporation of carbon dioxide into pyruvate. J. Bacteriol., 1953, 65, 744-745.
    • (1953) J. Bacteriol , vol.65 , pp. 744-745
    • Seaman, G.R.1
  • 165
    • 78651037853 scopus 로고
    • Role of thioctic acid in the transfer of acyl groups
    • Seaman, G. R. Role of thioctic acid in the transfer of acyl groups. Proc. Soc. Exp. Biol. Med., 1953, 82, 184-189.
    • (1953) Proc. Soc. Exp. Biol. Med , vol.82 , pp. 184-189
    • Seaman, G.R.1
  • 166
    • 37049239085 scopus 로고
    • Effect of synthetic thioctic or alpha lipoic acid on the voluntary alcohol intake of rats
    • Mardones, J.; Segovia, N.; Alcaino, F.; Hederra, a. Effect of synthetic thioctic or alpha lipoic acid on the voluntary alcohol intake of rats. Science, 1954, 119, 735-736.
    • (1954) Science , vol.119 , pp. 735-736
    • Mardones, J.1    Segovia, N.2    Alcaino, F.3    Hederra, A.4
  • 167
    • 0009467999 scopus 로고
    • Oxidative and transfer reactions of lipoic acid
    • Gunsalus, I. C. Oxidative and transfer reactions of lipoic acid. Fed. Proc., 1954, 13, 715-722.
    • (1954) Fed. Proc , vol.13 , pp. 715-722
    • Gunsalus, I.C.1
  • 168
    • 0018253371 scopus 로고
    • Radical scavenging as the mechanism for stimulation of prostaglandin cyclooikgenase and depression of inflammation by lipoic acid and sodim iodide
    • Egan, R. W.; Gale, P. H.; Beveridge, G. C.; Phillips, G. B.; Marnett, L. J. Radical scavenging as the mechanism for stimulation of prostaglandin cyclooikgenase and depression of inflammation by lipoic acid and sodim iodide. Prostaglandins, 1978, 16, 861-869.
    • (1978) Prostaglandins , vol.16 , pp. 861-869
    • Egan, R.W.1    Gale, P.H.2    Beveridge, G.C.3    Phillips, G.B.4    Marnett, L.J.5
  • 169
    • 0017344858 scopus 로고
    • Stimulation of prostaglandin biosynthesis by lipoic acid
    • Marnett, L. J.; Wilcox, C. L. Stimulation of prostaglandin biosynthesis by lipoic acid. Biochim. Biophys. Acta, 1977, 487, 222-230.
    • (1977) Biochim. Biophys. Acta , vol.487 , pp. 222-230
    • Marnett, L.J.1    Wilcox, C.L.2
  • 171
    • 38349144351 scopus 로고    scopus 로고
    • Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice
    • Zhang, W.-J.; Bird, K. E.; McMillen, T. S.; LeBoeuf, R. C.; Hagen, T. M.; Frei, B. Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice. Circulation, 2008, 117, 421-428.
    • (2008) Circulation , vol.117 , pp. 421-428
    • Zhang, W.-J.1    Bird, K.E.2    McMillen, T.S.3    LeBoeuf, R.C.4    Hagen, T.M.5    Frei, B.6
  • 173
    • 42749093595 scopus 로고    scopus 로고
    • Lipoic acid prevents high-fat diet-induced dyslipidemia and oxidative stress: A microarray analysis
    • Yang, R.-L.; Li, W.; Shi, Y.-H.; Le, G.-W. Lipoic acid prevents high-fat diet-induced dyslipidemia and oxidative stress: a microarray analysis. Nutrition, 2008, 24, 582-588.
    • (2008) Nutrition , vol.24 , pp. 582-588
    • Yang, R.-L.1    Li, W.2    Shi, Y.-H.3    Le, G.-W.4
  • 174
    • 43849104298 scopus 로고    scopus 로고
    • Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: Evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance
    • R Vinayagamoorthi, R.; Bobby, Z.; Sridhar, M. G. Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance. J. Endocrinol., 2008, 197, 287-296.
    • (2008) J. Endocrinol , vol.197 , pp. 287-296
    • Vinayagamoorthi, R.R.1    Bobby, Z.2    Sridhar, M.G.3
  • 175
    • 84858324850 scopus 로고    scopus 로고
    • Alpha lipoic Acid for symptomatic peripheral neuropathy in patients with diabetes: A meta-analysis of randomized controlled trials. Int
    • Mijnhout, G. S.; Kollen, B. J.; Alkhalaf, A.; Kleefstra, N.; Bilo, H. J. G. Alpha lipoic Acid for symptomatic peripheral neuropathy in patients with diabetes: a meta-analysis of randomized controlled trials. Int. J. Endocrinol., 2012, 2012, 456279.
    • (2012) J. Endocrinol , vol.2012
    • Mijnhout, G.S.1    Kollen, B.J.2    Alkhalaf, A.3    Kleefstra, N.4    Bilo, H.J.G.5
  • 176
    • 1242337352 scopus 로고    scopus 로고
    • Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: A meta-analysis
    • Ziegler, D.; Nowak, H.; Kempler, P.; Vargha, P.; Low, P. Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a meta-analysis. Diabet. Med., 2004, 21, 114-121.
    • (2004) Diabet. Med , vol.21 , pp. 114-121
    • Ziegler, D.1    Nowak, H.2    Kempler, P.3    Vargha, P.4    Low, P.5
  • 177
    • 33845499323 scopus 로고    scopus 로고
    • Oral Treatment With a-Lipoic Acid Improves Symptomatic Diabetic Polyneuropathy: The SYDNEY 2 trial
    • Ziegler, D.; Ameton, A.; Barinov, A.; Dyck, P. J.; Low, P. A. Oral Treatment With a-Lipoic Acid Improves Symptomatic Diabetic Polyneuropathy: The SYDNEY 2 trial. Diabetes Care, 2006, 29, 2265-2270.
    • (2006) Diabetes Care , vol.29 , pp. 2265-2270
    • Ziegler, D.1    Ameton, A.2    Barinov, A.3    Dyck, P.J.4    Low, P.A.5
  • 179
    • 84872146192 scopus 로고    scopus 로고
    • Direct and indirect antioxidant properties of α-lipoic acid and therapeutic potential
    • Rochette, L.; Ghibu, S.; Richard, C.; Zeller, M.; Cottin, Y.; Vergely, C. Direct and indirect antioxidant properties of α-lipoic acid and therapeutic potential. Mol. Nutr. Food Res., 2013, 57, 114-125.
    • (2013) Mol. Nutr. Food Res , vol.57 , pp. 114-125
    • Rochette, L.1    Ghibu, S.2    Richard, C.3    Zeller, M.4    Cottin, Y.5    Vergely, C.6
  • 180
    • 0032881613 scopus 로고    scopus 로고
    • Treatment of diabetic polyneuropathy with the antioxidant thioctic acid [α-lipoic acid]: A two year multicenter randomized double-blind placebo-controlled trial [ALADIN II]. Reljanovic
    • Reljanovic, M.; Reichel, G.; Rett, K.; Lobisch, M.; Schuette, K.; Moller, W.; Tritschler, H.-J.; Mehnert, H. Treatment of diabetic polyneuropathy with the antioxidant thioctic acid [α-lipoic acid]: a two year multicenter randomized double-blind placebo-controlled trial [ALADIN II]. Reljanovic,. Free Radic. Res., 1999, 31, 171-179.
    • (1999) Free Radic. Res , vol.31 , pp. 171-179
    • Reljanovic, M.1    Reichel, G.2    Rett, K.3    Lobisch, M.4    Schuette, K.5    Moller, W.6    Tritschler, H.-J.7    Mehnert, H.8
  • 181
    • 43649103795 scopus 로고    scopus 로고
    • Dietary lipoic acid supplementation can mimic or block the effect of dietary restriction on life span. Mech
    • Merry, B. J.; Kirk, A. J.; Goyns, M. H. Dietary lipoic acid supplementation can mimic or block the effect of dietary restriction on life span. Mech. Ageing Dev., 2008, 129, 341-348.
    • (2008) Ageing Dev , vol.129 , pp. 341-348
    • Merry, B.J.1    Kirk, A.J.2    Goyns, M.H.3
  • 182
    • 56049107269 scopus 로고    scopus 로고
    • Dietary supplementation with N-acetylcysteine, alpha-tocopherol and alphalipoic acid prevents age related decline in Na[+], K [+]-ATPase activity and associated peroxidative damage in rat brain synaptosomes
    • Bagh, M. B.; Maiti, A. K.; Roy, A.; Chakrabarti, S. Dietary supplementation with N-acetylcysteine, alpha-tocopherol and alphalipoic acid prevents age related decline in Na[+], K [+]-ATPase activity and associated peroxidative damage in rat brain synaptosomes. Biogerontology, 2008, 9, 421-428.
    • (2008) Biogerontology , vol.9 , pp. 421-428
    • Bagh, M.B.1    Maiti, A.K.2    Roy, A.3    Chakrabarti, S.4
  • 183
    • 0033088957 scopus 로고    scopus 로고
    • Review: The role of glutathione in the regulation of apoptosis
    • Hall, A. G. Review: The role of glutathione in the regulation of apoptosis. Eur. J. Clin. Invest., 1999, 29, 238-245.
    • (1999) Eur. J. Clin. Invest , vol.29 , pp. 238-245
    • Hall, A.G.1
  • 184
    • 0030729441 scopus 로고    scopus 로고
    • A method for measuring nitric oxide radical scavenging activity. Scavenging properties of sulfur-containing compounds
    • Vriesman, M. F.; Haenen, G. R.; Westerveld, G. J.; Paquay, J. B.; Voss, H. P.; Bast, a. A method for measuring nitric oxide radical scavenging activity. Scavenging properties of sulfur-containing compounds. Pharm. World Sci., 1997, 19, 283-286.
    • (1997) Pharm. World Sci , vol.19 , pp. 283-286
    • Vriesman, M.F.1    Haenen, G.R.2    Westerveld, G.J.3    Paquay, J.B.4    Voss, H.P.5    Bast, A.6
  • 186
    • 84889575198 scopus 로고    scopus 로고
    • Modulation of oxidative stress as an anticancer strategy
    • Gorrini, C.; Harris, I. S.; Mak, T. W. Modulation of oxidative stress as an anticancer strategy. Nat. Rev. Drug Discov., 2013, 12, 931-947.
    • (2013) Nat. Rev. Drug Discov , vol.12 , pp. 931-947
    • Gorrini, C.1    Harris, I.S.2    Mak, T.W.3
  • 188
    • 84902000346 scopus 로고    scopus 로고
    • The failure of cancer chemoprevention
    • Potter, J. D. The failure of cancer chemoprevention. Carcinogenesis, 2014, 35, 974-982.
    • (2014) Carcinogenesis , vol.35 , pp. 974-982
    • Potter, J.D.1
  • 189
    • 84755160977 scopus 로고    scopus 로고
    • Efficacy of combined topiramate/thioctic acid therapy in migraine prophylaxis
    • Ali, A. M.; Awad, T. G.; Al-Adl, N. M. Efficacy of combined topiramate/thioctic acid therapy in migraine prophylaxis. Saudi Pharm. J., 2010, 18(4), 239-243.
    • (2010) Saudi Pharm. J , vol.18 , Issue.4 , pp. 239-243
    • Ali, A.M.1    Awad, T.G.2    Al-Adl, N.M.3
  • 190
    • 77955095952 scopus 로고    scopus 로고
    • Comparative proteome analysis of splenic lymphocytes in long-term high-fat diet and dietary supplement with lipoic acid mice
    • Cui, J.; Xiao, Y.; Shi, Y.; Le, G.; Miao, X. Comparative proteome analysis of splenic lymphocytes in long-term high-fat diet and dietary supplement with lipoic acid mice. Cell. Immunol., 2010, 264, 156-162.
    • (2010) Cell. Immunol , vol.264 , pp. 156-162
    • Cui, J.1    Xiao, Y.2    Shi, Y.3    Le, G.4    Miao, X.5
  • 191
    • 84860598278 scopus 로고    scopus 로고
    • Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response
    • Shay, K.; Michels, A.; Li, W. Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response. Biochim. Biophys. Acta, 2012, 1823, 1102-1109.
    • (2012) Biochim. Biophys. Acta , vol.1823 , pp. 1102-1109
    • Shay, K.1    Michels, A.2    Li, W.3
  • 192
    • 33746362930 scopus 로고    scopus 로고
    • Effect of chronic restraint stress and alpha-lipoic acid on lipid peroxidation and antioxidant enzyme activities in rat peripheral organs
    • Sahin, M.; Sağdic, G.; Elmas, O.; Akpinar, D.; Derin, N.; Aslan, M.; Agar, A.; Aliciguzel, Y.; Yargicoğlu, P. Effect of chronic restraint stress and alpha-lipoic acid on lipid peroxidation and antioxidant enzyme activities in rat peripheral organs. Pharmacol. Res., 2006, 54, 247-252.
    • (2006) Pharmacol. Res , vol.54 , pp. 247-252
    • Sahin, M.1    Sağdic, G.2    Elmas, O.3    Akpinar, D.4    Derin, N.5    Aslan, M.6    Agar, A.7    Aliciguzel, Y.8    Yargicoğlu, P.9
  • 193
    • 84864688209 scopus 로고    scopus 로고
    • Quantum-chemical investigation of the structure and the antioxidant properties of α-lipoic acid and its metabolites
    • Szeląg, M.; Mikulski, D.; Molski, M. Quantum-chemical investigation of the structure and the antioxidant properties of α-lipoic acid and its metabolites. J. Mol. Model, 2012, 18, 2907-2916.
    • (2012) J. Mol. Model , vol.18 , pp. 2907-2916
    • Szeląg, M.1    Mikulski, D.2    Molski, M.3
  • 194
    • 1042290476 scopus 로고    scopus 로고
    • [R]-alphalipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: Evidence for increased cysteine requirement for GSH synthesis
    • Suh, J. H.; Wang, H.; Liu, R.-M.; Liu, J.; Hagen, T. M. [R]-alphalipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: evidence for increased cysteine requirement for GSH synthesis. Arch. Biochem. Biophys., 2004, 423, 126-135.
    • (2004) Arch. Biochem. Biophys , vol.423 , pp. 126-135
    • Suh, J.H.1    Wang, H.2    Liu, R.-M.3    Liu, J.4    Hagen, T.M.5
  • 195
    • 4544253738 scopus 로고    scopus 로고
    • Lumbar radicular pain
    • Govind, J. Lumbar radicular pain. Aust. Fam. Physician, 2004, 33, 409-412.
    • (2004) Aust. Fam. Physician , vol.33 , pp. 409-412
    • Govind, J.1
  • 196
    • 84884938910 scopus 로고    scopus 로고
    • The effect of reactive oxygen species on the synthesis of prostanoids from arachidonic acid
    • Korbecki, J. The effect of reactive oxygen species on the synthesis of prostanoids from arachidonic acid. J. Physiol. Pharmacol., 2013, 64, 409-421.
    • (2013) J. Physiol. Pharmacol , vol.64 , pp. 409-421
    • Korbecki, J.1
  • 197
    • 63649163373 scopus 로고    scopus 로고
    • Alpha-lipoic acid modifies oxidative stress parameters in sickle cell trait subjects and sickle cell patients
    • Martins, V. D.; Manfredini, V.; Peralba, M. C. R.; Benfato, M. S. Alpha-lipoic acid modifies oxidative stress parameters in sickle cell trait subjects and sickle cell patients. Clin. Nutr., 2009, 28, 192-197.
    • (2009) Clin. Nutr , vol.28 , pp. 192-197
    • Martins, V.D.1    Manfredini, V.2    Peralba, M.C.R.3    Benfato, M.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.