Hypermetabolic state in the 7-month-old triple transgenic mouse model of Alzheimer's disease and the effect of lipoic acid: A 13 C-NMR study

Journal of Cerebral Blood Flow and Metabolism

Volumn 34, Issue 11, 2014, Pages 1749-1760

  Sancheti, Harsh ^a   Patil, Ishan ^a   Kanamori, Keiko ^b   Díaz Brinton, Roberta ^a   Zhang, Wei ^c   Lin, Ai Ling ^d   Cadenas, Enrique ^d  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b HUNTINGTON MEDICAL RESEARCH INSTITUTES   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

13C nuclear magnetic resonance; Alzheimer's disease; glutamate isotopomers; hypermetabolism; lipoic acid; 1 13C glucose metabolism

Indexed keywords

4 AMINOBUTYRIC ACID; ACETIC ACID; ASPARTIC ACID; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; N ACETYLASPARTIC ACID; THIOCTIC ACID; CARBON; SWEETENING AGENT; VITAMIN B COMPLEX;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN NERVE CELL; CARBON NUCLEAR MAGNETIC RESONANCE; CITRIC ACID CYCLE; CONTROLLED STUDY; DRUG EFFECT; EX VIVO STUDY; GLUCOSE BRAIN LEVEL; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERMETABOLISM; ISOTOPE LABELING; MALE; METABOLIC PARAMETERS; METABOLIC RATIO; MOUSE; MOUSE MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SOMATOSENSORY CORTEX; TRANSGENIC MOUSE; ANIMAL; DIET SUPPLEMENTATION; DISEASE MODEL; GENETICS; HUMAN; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY;

ALZHEIMER DISEASE; ANIMALS; CARBON ISOTOPES; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; GLUCOSE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, TRANSGENIC; SWEETENING AGENTS; THIOCTIC ACID; VITAMIN B COMPLEX;

EID: 84922219033     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2014.137     Document Type: Article

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