Vascular function and the role of oxidative stress in heart failure, heart transplant, and beyond

Hypertension

Volumn 60, Issue 3, 2012, Pages 659-668

  Witman, Melissa A H ^a,b   Fjeldstad, Anette S ^c   McDaniel, John ^a,d   Ives, Stephen J ^a,b   Zhao, Jia ^c   Barrett O'Keefe, Zachary ^a,b   Nativi, Jose N ^c   Stehlik, Josef ^c   Wray, D Walter ^a,b,c   Richardson, Russell S ^a,b,c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d KENT STATE UNIVERSITY   (United States)

Author keywords

antioxidants; blood flow; flow mediated vasodilation; vascular health

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CATALASE; ENDOTHELIN 1; PLACEBO; SUPEROXIDE DISMUTASE; THIOCTIC ACID;

ADULT; ARTICLE; BRACHIAL ARTERY; CARDIOVASCULAR FUNCTION; CARDIOVASCULAR SYSTEM EXAMINATION; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; ENZYME ACTIVITY; FEMALE; FLOW MEDIATED VASODILATION; GRAFT RECIPIENT; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART TRANSPLANTATION; HUMAN; HYPEREMIA; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; VASODILATATION;

AGED; ANTIOXIDANTS; ASCORBIC ACID; BRACHIAL ARTERY; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; DISEASE PROGRESSION; FEMALE; HEART FAILURE; HEART TRANSPLANTATION; HUMANS; HYPEREMIA; MALE; MIDDLE AGED; OXIDATIVE STRESS; STROKE VOLUME; THIOCTIC ACID; VASODILATION; VITAMIN E;

EID: 84865520840     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.112.193318     Document Type: Article

References (55)

1. Panza JA, Quyyumi AA, Brush JE Jr, Epstein SE. Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension. N Engl J Med. 1990;323:22-27.
2. Monnink SH, van Haelst PL, van Boven AJ, Stroes ES, Tio RA, Plokker TW, Smit AJ, Veeger NJ, Crijns HJ, van Gilst WH. Endothelial dysfunction in patients with coronary artery disease: a comparison of three frequently reported tests. J Investig Med. 2002;50:19-24.
3. Katz SD, Biasucci L, Sabba C, Strom JA, Jondeau G, Galvao M, Solomon S, Nikolic SD, Forman R, LeJemtel TH. Impaired endothelium-mediated vasodilation in the peripheral vasculature of patients with congestive heart failure. J Am Coll Cardiol. 1992;19:918-925.
4. Drexler H, Hayoz D, Munzel T, Hornig B, Just H, Brunner HR, Zelis R. Endothelial function in chronic congestive heart failure. Am J Cardiol. 1992;69:1596-1601.
5. Celermajer D, Sorensen K, Spiegelhalter D, Georgakopoulos D, Robinson J, Deanfield J. Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women. J Am Coll Cardiol. 1994;24:471.
6. Celermajer DS, Sorensen KE, Gooch VM, Spiegelhalter DJ, Miller OI, Sullivan ID, Lloyd JK, Deanfield JE. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet. 1992;340:1111-1115.
7. Huang AL, Silver AE, Shvenke E, Schopfer DW, Jahangir E, Titas MA, Shpilman A, Menzoian JO, Watkins MT, Raffetto JD, Gibbons G, Woodson J, Shaw PM, Dhadly M, Eberhardt RT, Keaney JF Jr, Gokce N, Vita JA. Predictive value of reactive hyperemia for cardiovascular events in patients with peripheral arterial disease undergoing vascular surgery. Arterioscler Thromb Vasc Biol. 2007;27:2113-2119.
8. Mitchell GF, Parise H, Vita JA, Larson MG, Warner E, Keaney JF Jr, Keyes MJ, Levy D, Vasan RS, Benjamin EJ. Local shear stress and brachial artery flow-mediated dilation: the Framingham Heart Study. Hypertension. 2004;44:134-139.
9. Hasking GJ, Esler MD, Jennings GL, Dewar E, Lambert G. Norepinephrine spillover to plasma during steady-state supine bicycle exercise: comparison of patients with congestive heart failure and normal subjects. Circulation. 1988;78:516-521.
10. Francis GS, Rector TS, Cohn JN. Sequential neurohumoral measurements in patients with congestive heart failure. Am Heart J. 1988;116: 1464-1468.
11. Katz SD, Khan T, Zeballos GA, Mathew L, Potharlanka P, Knecht M, Whelan J. Decreased activity of the l-arginine-nitric oxide metabolic pathway in patients with congestive heart failure. Circulation. 1999;99: 2113-2117.
12. Bauersachs J, Bouloumie A, Fraccarollo D, Hu K, Busse R, Ertl G. Endothelial dysfunction in chronic myocardial infarction despite increased vascular endothelial nitric oxide synthase and soluble guanylate cyclase expression: role of enhanced vascular superoxide production. Circulation. 1999;100:292-298.
13. Gryglewski RJ, Palmer RM, Moncada S. Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature. 1986;320:454-456.
14. Wei EP, Kontos HA, Christman CW, DeWitt DS, Povlishock JT. Superoxide generation and reversal of acetylcholine-induced cerebral arteriolar dilation after acute hypertension. Circ Res. 1985;57: 781-787.
15. Kubo SH, Rector TS, Bank AJ, Williams RE, Heifetz SM. Endotheliumdependent vasodilation is attenuated in patients with heart failure. Circulation. 1991;84:1589-1596.
16. Eskurza I, Monahan KD, Robinson JA, Seals DR. Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing. J Physiol. 2004;556:315-324.
17. Donato AJ, Uberoi A, Bailey DM, Wray DW, Richardson RS. Exerciseinduced brachial artery vasodilation: effects of antioxidants and exercise training in elderly men. Am J Physiol Heart Circ Physiol. 2010;298: H671-H678.
18. Wray DW, Nishiyama SK, Harris RA, Zhao J, McDaniel J, Fjeldstad AS, Witman MA, Ives SJ, Barrett-O'Keefe Z, Richardson RS. Acute reversal of endothelial dysfunction in the elderly after antioxidant consumption. Hypertension. 2012;59:818-824.
19. Hornig B, Arakawa N, Kohler C, Drexler H. Vitamin C improves endothelial function of conduit arteries in patients with chronic heart failure. Circulation. 1998;97:363-368.
20. Kubo SH, Rector TS, Bank AJ, Tschumperlin LK, Raij L, Brunsvold N, Kraemer MD. Effects of cardiac transplantation on endotheliumdependent dilation of the peripheral vasculature in congestive heart failure. Am J Cardiol. 1993;71:88-93.
21. Roig E, Cuppoletti A, Masotti M, Kianco R, Vallejos I, Sitges M, Ortiz J, Perez-Villa F. Assessment of peripheral endothelial-dependent vasodilatation within the first year after heart transplantation. J Heart Lung Transplant. 2009;28:299-304.
22. Diederich D, Skopec J, Diederich A, Dai FX. Cyclosporine produces endothelial dysfunction by increased production of superoxide. Hypertension. 1994;23:957-961.
23. Mugge A, Brandes RP, Heublein B, Nolte C, Haverich A, Lichtlen PR. Endothelial dysfunction in heart transplanted patients with graft vasculopathy. European heart journal. 1995;16(suppl J)78-83.
24. Sinoway LI, Minotti JR, Davis D, Pennock JL, Burg JE, Musch TI, Zelis R. Delayed reversal of impaired vasodilation in congestive heart failure after heart transplantation. Am J Cardiol. 1988;61:1076-1079.
25. Harris RA, Nishiyama SK, Wray DW, Tedjasaputra V, Bailey DM, Richardson RS. The effect of oral antioxidants on brachial artery flowmediated dilation following 5 and 10 min of ischemia. Eur J Appl Physiol. 2009;107:445-453.
26. Harris RA, Nishiyama SK, Wray DW, Richardson RS. Ultrasound assessment of flow-mediated dilation. Hypertension. 2010;55: 1075-1085.
27. Wray DW, Uberoi A, Lawrenson L, Bailey DM, Richardson RS. Oral antioxidants and cardiovascular health in the exercise-trained and untrained elderly: a radically different outcome. Clin Sci (Lond). 2009; 116:433-441.
28. Yagi K. A simple fluorometric assay for lipoperoxide in blood plasma. Biochem Med. 1976;15:212-216.
29. Wheeler CR, Salzman JA, Elsayed NM, Omaye ST, Korte DW Jr. Automated assays for superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase activity. Anal Biochem. 1990;184: 193-199.
30. Bradley DW, Emery G, Maynard JE. Vitamin C in plasma: a comparative study of the vitamin stabilized with trichloroacetic acid or metaphosphoric acid and the effects of storage at-70,-20, 4, and 25 on the stabilized vitamin. Clinica Chimica Acta. 1973;44:47-52.
31. Levine TB, Olivari MT, Cohn JN. Effects of orthotopic heart transplantation on sympathetic control mechanisms in congestive heart failure. Am J Cardiol. 1986;58:1035-1040.
32. Patel AR, Kuvin JT, Pandian NG, Smith JJ, Udelson JE, Mendelsohn ME, Konstam MA, Karas RH. Heart failure etiology affects peripheral vascular endothelial function after cardiac transplantation. J Am Coll Cardiol. 2001;37:195-200.
33. Schmidt A, Pleiner J, Bayerle-Eder M, Wiesinger GF, Rodler S, Quittan M, Mayer G, Wolzt M. Regular physical exercise improves endothelial function in heart transplant recipients. Clin Transplant. 2002;16:137-143.
34. Klosinska M, Rudzinski T, Grzelak P, Stefanczyk L, Drozdz J, Krzeminska-Pakula M. Endothelium-dependent and-independent vasodilation is more attenuated in ischaemic than in non-ischaemic heart failure. Eur J Heart Fail. 2009;11:765-770.
35. Furchgott RF. The 1989 Ulf Von Euler Lecture: studies on endotheliumdependent vasodilation and the endothelium-derived relaxing factor. Acta Physiol Scand. 1990;139:257-270.
36. Lindenfeld J, Miller GG, Shakar SF, Zolty R, Lowes BD, Wolfel EE, Mestroni L, Page RL, Page RL, Kobashigawa J. Drug therapy in the heart transplant recipient: part I-cardiac rejection and immunosuppressive drugs. Circulation. 2004;110:3734-3740.
37. Morgan DR, Dixon LJ, Hanratty CG, Hughes SM, Leahey WJ, Rooney KP, Johnston GD, McVeigh GE. Impaired endothelium-dependent and-independent vasodilation in elderly patients with chronic heart failure. Eur J Heart Fail. 2004;6:901-908.
38. Scott JM, Esch BT, Haykowsky MJ, Warburton DE, Toma M, Jelani A, Taylor D, Paterson I, Poppe D, Liang Y, Thompson R. Cardiovascular responses to incremental and sustained submaximal exercise in heart transplant recipients. Am J Physiol Heart Circ Physiol. 2009;296: H350-H358.
39. Kao A, Van Trigt III P, Shaeffer-McCall G, Shaw J, Kuzil B, Page R, Higginbotham M. Central and peripheral limitations to upright exercise in untrained cardiac transplant recipients. Circulation. 1994; 89:2605.
40. Petrakopoulou P, Kubrich M, Pehlivanli S, Meiser B, Reichart B, von Scheidt W, Weis M. Cytomegalovirus infection in heart transplant recipients is associated with impaired endothelial function. Circulation. 2004;110:II207- II212.
41. Jeanmart H, Malo O, Carrier M, Nickner C, Desjardins N, Perrault LP. Comparative study of cyclosporine and tacrolimus vs newer immunosuppressants mycophenolate mofetil and rapamycin on coronary endothelial function. J Heart Lung Transplant. 2002;21:990-998.
42. Stehlik J, Edwards LB, Kucheryavaya AY, Benden C, Christie JD, Dobbels F, Kirk R, Rahmel AO, Hertz MI. The registry of the International Society for Heart and Lung Transplantation: twenty-eighth adult heart transplant report-2011. J Heart Lung Transplant. 2011;30: 1078-1094.
43. Zoja C, Furci L, Ghilardi F, Zilio P, Benigni A, Remuzzi G. Cyclosporininduced endothelial cell injury. Lab Investig. 1986;55:455-462.
44. Voss BL, Hamilton KK, Samara EN, McKee PA. Cyclosporine suppression of endothelial prostacyclin generation: a possible mechanism for nephrotoxicity. Transplant. 1988;45:793-796.
45. Bunchman TE, Brookshire CA. Cyclosporine-induced synthesis of endothelin by cultured human endothelial cells. J Clin Investig. 1991;88: 310-314.
46. Schrama YC, van Dam T, Fijnheer R, Hene RJ, de Groot P, Rabelink TJ. Cyclosporine is associated with endothelial dysfunction but not with platelet activation in renal transplantation. Neth J Med. 2001; 59:6-15.
47. Loscalzo J, Vita JA. Ischemia, hyperemia, exercise, and nitric oxide: complex physiology and complex molecular adaptations. Circulation. 1994;90:2556-2559.
48. Meredith IT, Currie KE, Anderson TJ, Roddy MA, Ganz P, Creager MA. Postischemic vasodilation in human forearm is dependent on endothelium-derived nitric oxide. Am J Physiol. 1996;270:H1435-H1440.
49. Musch TI, Terrell JA. Skeletal muscle blood flow abnormalities in rats with a chronic myocardial infarction: rest and exercise. Am J Physiol. 1992;262:H411-H419.
50. McAllister RM, Laughlin MH, Musch TI. Effects of chronic heart failure on skeletal muscle vascular transport capacity of rats. Am J Physiol. 1993;264:H689-H691.
51. Hambrecht R, Fiehn E, Weigl C, Gielen S, Hamann C, Kaiser R, Yu J, Adams V, Niebauer J, Schuler G. Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure. Circulation. 1998;98:2709-2715.
52. Kleinbongard P, Dejam A, Lauer T, Jax T, Kerber S, Gharini P, Balzer J, Zotz RB, Scharf RE, Willers R, Schechter AN, Feelisch M, Kelm M. Plasma nitrite concentrations reflect the degree of endothelial dysfunction in humans. Free Radic Biol Med. 2006;40:295-302.
53. Winlaw DS, Smythe GA, Keogh AM, Schyvens CG, Spratt PM, Macdonald PS. Increased nitric oxide production in heart failure. Lancet. 1994;344:373-374.
54. Szabo C, Day BJ, Salzman AL. Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger. FEBS Lett. 1996;381:82-86.
55. Silvestro A, Scopacasa F, Oliva G, de Cristofaro T, Iuliano L, Brevetti G. Vitamin c prevents endothelial dysfunction induced by acute exercise in patients with intermittent claudication. Atherosclerosis. 2002;165: 277-283.