Inflammation and apoptosis in aortic tissues of aged type II diabetes: Amelioration with α-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism

Life Sciences

Volumn 86, Issue 23-24, 2010, Pages 844-853

  Bitar, Milad S ^a   Ayed, Adel K ^a   Abdel Halim, Samy M ^b   Isenovic, Esma R ^c   Al Mulla, Fahd ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

^b UPPSALA UNIVERSITY   (Sweden)

^c UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

lipoic acid; Apoptosis; Diabetes; Inflammation; Oxidative stress

Indexed keywords

FRACTALKINE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; MYELOPEROXIDASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SYNAPTOTAGMIN I; THIOCTIC ACID; TUMOR NECROSIS FACTOR ALPHA; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; AORTA; APOPTOSIS; ARTICLE; CARDIOVASCULAR DISEASE; CELL NUCLEUS; CHRONIC INFLAMMATION; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; GOTO KAKIZAKI RAT; IMMUNOFLUORESCENCE TEST; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETOPHENONES; AGING; ANDROSTADIENES; ANIMALS; ANTIOXIDANTS; AORTA; APOPTOSIS; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; INFLAMMATION; MALE; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; THIOCTIC ACID; VASODILATION;

RATTUS;

EID: 77953022783     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.03.019     Document Type: Article

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