Alpha-lipoic acid reduces LDL-particle number and PCSK9 concentrations in high-fat fed obese Zucker rats

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Carrier, Bradley ^a   Wen, Shin ^a   Zigouras, Sophia ^a   Browne, Richard W ^b   Li, Zhuyun ^a   Patel, Mulchand S ^b   Williamson, David L ^a   Rideout, Todd C ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; CARNITINE PALMITOYLTRANSFERASE I; CARNITINE PALMITOYLTRANSFERASE I ALPHA; CARNITINE PALMITOYLTRANSFERASE I BETA; CHOLESTEROL; FATTY ACID SYNTHASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; KEXIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; PROTEIN PCSK9; THIOCTIC ACID; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANOREXIA; ARTICLE; BIOLOGICAL ACTIVITY; BODY WEIGHT; CALORIC INTAKE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL METABOLISM; DIETARY INTAKE; DOWN REGULATION; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVITY; FATTY ACID OXIDATION; FATTY ACID TRANSPORT; FEEDING; GENE EXPRESSION; GENETIC PREDISPOSITION; HEPATIC FAT OXIDATION; HYPERCHOLESTEROLEMIA; HYPOLIPIDEMIC ACTIVITY; LIPID DIET; LIVER; MUSCLE TISSUE; NONHUMAN; OBESITY; PROTEIN EXPRESSION; RAT; TRIACYLGLYCEROL BLOOD LEVEL; ZUCKER RAT;

ANIMALS; ANTIOXIDANTS; DIET, HIGH-FAT; ENERGY INTAKE; LIPOPROTEINS, LDL; LIVER; MALE; OBESITY; RATS; RATS, ZUCKER; SERINE ENDOPEPTIDASES; THIOCTIC ACID; TRIGLYCERIDES;

EID: 84897077564     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090863     Document Type: Article

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