Ochratoxin A induces karyomegaly and cell cycle aberrations in renal tubular cells without relation to induction of oxidative stress responses in rats

Toxicology Letters

Volumn 224, Issue 1, 2014, Pages 64-72

  Taniai, Eriko ^a,b   Yafune, Atsunori ^a,b   Nakajima, Masahiro ^c   Hayashi, Shim Mo ^d   Nakane, Fumiyuki ^a   Itahashi, Megu ^a,b   Shibutani, Makoto ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b GIFU UNIVERSITY   (Japan)

^c NAGOYA CITY PUBLIC HEALTH RESEARCH INSTITUTE   (Japan)

^d SAN EI GEN F F I INC   (Japan)

Author keywords

Apoptosis; Cell cycle; Cell proliferation; Ochratoxin A; Oxidative stress; Renal carcinogenesis

Indexed keywords

GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE PEROXIDASE 2; GLUTATHIONE TRANSFERASE A5; GLUTATHIONE TRANSFERASE M1; ISOQUERCITRIN; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MESSENGER RNA; OCHRATOXIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOCTIC ACID; TRANSCRIPTION FACTOR NRF2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL CYCLE; CELL CYCLE ARREST; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CHROMOSOME ABERRATION; DNA DAMAGE; FLUID INTAKE; FOOD INTAKE; GENE; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KARYOMEGALY; KIDNEY MASS; KIDNEY TUBULE CELL; LIPID PEROXIDATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

RATTUS;

EID: 84887565465     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.10.001     Document Type: Article

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