The neuroprotective benefit from pioglitazone (PIO) addition on the alpha lipoic acid (ALA)-based treatment in experimental diabetic rats

Endocrine

Volumn 47, Issue 3, 2014, Pages 772-782

  Jin, Heung Yong ^a   Lee, Kyung Ae ^a   Wu, Jin Zu ^a   Baek, Hong Sun ^a   Park, Tae Sun ^a  

^a Chonbuk National University Medical School and Hospital   (South Korea)

Author keywords

Alpha lipoic acid; Diabetic peripheral neuropathy; Pioglitazone

Indexed keywords

GLUCOSE; PIOGLITAZONE; SUPEROXIDE DISMUTASE; THIOCTIC ACID; 2,4 THIAZOLIDINEDIONE DERIVATIVE; GLUCOSE BLOOD LEVEL; NEUROPROTECTIVE AGENT;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; EXPERIMENTAL DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; LIPID ANALYSIS; MALE; MONOTHERAPY; MYELINATED NERVE; NERVE FIBER; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PERCEPTIVE THRESHOLD; PERIPHERAL NEUROPATHY; RAT; SCIATIC NERVE; SKIN BLOOD FLOW; ANIMAL; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; DRUG COMBINATION; DRUG EFFECTS; HYPERALGESIA; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; AXONS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; DRUG THERAPY, COMBINATION; HYPERALGESIA; MALE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; THIAZOLIDINEDIONES; THIOCTIC ACID;

EID: 84911976607     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-014-0198-x     Document Type: Article

References (33)

1. F. Becic, E. Kapic, M. Rakanovic-Todic, Pharmacological significance of alpha lipoic acid in up to date treatment of diabetic neuropathy. Med. Arh. 62, 45–48 (2008)
2. J.L. Evans, I.D. Goldfine, Alpha-lipoic acid: a multifunctional antioxidant that improves insulin sensitivity in patients with type 2 diabetes. Diabetes Technol. Ther. 2, 401–413 (2000)
3. D. Ziegler, M. Reljanovic, H. Mehnert, F.A. Gries, Alpha-lipoic acid in the treatment of diabetic polyneuropathy in Germany: current evidence from clinical trials. Exp. Clin. Endocrinol. Diabetes 107, 421–430 (1999)
4. J. Shakher, M.J. Stevens, Update on the management of diabetic polyneuropathies. Diabetes Metab. Syndr. Obes. 4, 289–305 (2011)
5. I.G. Obrosova, Diabetic painful and insensate neuropathy: pathogenesis and potential treatments. Neurotherapeutics 6, 638–647 (2009)
6. R. Dumasia, K.A. Eagle, E. Kline-Rogers, N. May, L. Cho et al., Role of PPAR- gamma agonist thiazolidinediones in treatment of pre-diabetic and diabetic individuals: a cardiovascular perspective. Curr. Drug Targets Cardiovasc. Haematol. Disord. 5, 377–386 (2005)
7. X. Qiang, J. Satoh, M. Sagara, M. Fukuzawa, T. Masuda et al., Inhibitory effect of troglitazone on diabetic neuropathy in streptozotocin-induced diabetic rats. Diabetologia 41, 1321–1326 (1998)
8. S. Yamagishi, S. Ogasawara, H. Mizukami, N. Yajima, R. Wada et al., Correction of protein kinase C activity and macrophage migration in peripheral nerve by pioglitazone, peroxisome proliferator activated-gamma-ligand, in insulin-deficient diabetic rats. J. Neurochem. 104, 491–499 (2008)
9. T.D. Wiggin, M. Kretzler, S. Pennathur, K.A. Sullivan, F.C. Brosius et al., Rosiglitazone treatment reduces diabetic neuropathy in streptozotocin-treated DBA/2 J mice. Endocrinology 149, 4928–4937 (2008)
10. T. Maeda, N. Kiguchi, Y. Kobayashi, M. Ozaki, S. Kishioka, Pioglitazone attenuates tactile allodynia and thermal hyperalgesia in mice subjected to peripheral nerve injury. J. Pharmacol. Sci. 108, 341–347 (2008)
11. T. Zor, Z. Selinger, Linearization of the Bradford protein assay increases its sensitivity: theoretical and experimental studies. Anal. Biochem. 236, 302–308 (1996)
12. S. Weinstein, Tactile sensitivity of the phalanges. Percept. Mot. Skills 14, 351–354 (1962)
13. H.Y. Jin, S.H. Kim, H.M. Yu, H.S. Baek, T.S. Park, Therapeutic potential of dioscorea extract (DA-9801) in comparison with alpha lipoic acid on the peripheral nerves in experimental diabetes. J. Diabetes Res. 2013, 631218 (2013)
14. S.R. Chaplan, F.W. Bach, J.W. Pogrel, J.M. Chung, T.L. Yaksh, Quantitative assessment of tactile allodynia in the rat paw. J. Neurosci. Methods 53, 55–63 (1994)
15. H.Y. Jin, W.J. Liu, J.H. Park, H.S. Baek, T.S. Park, Effect of dipeptidyl peptidase-IV (DPP-IV) inhibitor (Vildagliptin) on peripheral nerves in streptozotocin-induced diabetic rats. Arch. Med. Res. 40, 536–544 (2009)
16. E. Asensio-Pinilla, E. Udina, J. Jaramillo, X. Navarro, Electrical stimulation combined with exercise increase axonal regeneration after peripheral nerve injury. Exp. Neurol. 219, 258–265 (2009)
17. J.L. Evans, I.D. Goldfine, B.A. Maddux, G.M. Grodsky, Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr. Rev. 23, 599–622 (2002)
18. Obrosova IG, Drel VR, Pacher P, Ilnytska O, Wang ZQ, et al. (2005) Oxidative-nitrosative stress and poly(ADP-ribose) polymerase (PARP) activation in experimental diabetic neuropathy: the relation is revisited. Diabetes 54: 3435-3441
19. A.M. Vincent, J.W. Russell, P. Low, E.L. Feldman, Oxidative stress in the pathogenesis of diabetic neuropathy. Endocr. Rev. 25, 612–628 (2004)
20. S. Tesfaye, Advances in the management of diabetic peripheral neuropathy. Curr. Opin. Support Palliat. Care 3, 136–143 (2009)
21. B. Desvergne, W. Wahli, Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr. Rev. 20, 649–688 (1999)
22. S. Giannini, M. Serio, A. Galli, Pleiotropic effects of thiazolidinediones: taking a look beyond antidiabetic activity. J. Endocrinol. Invest. 27, 982–991 (2004)
23. Y.H. Gong, X.R. Yu, H.L. Liu, N. Yang, P.P. Zuo et al., Antinociceptive effects of combination of Tramadol and Acetaminophen on painful diabetic neuropathy in streptozotocin-induced diabetic rats. Acta Anaesthesiol. Taiwan 49, 16–20 (2011)
24. M.J. Walker Jr, L.M. Morris, D. Cheng, Improvement of cutaneous sensitivity in diabetic peripheral neuropathy with combination l-methylfolate, methylcobalamin, and pyridoxal 5’-phosphate. Rev. Neurol. Dis. 7, 132–139 (2010)
25. Y. Liu, N. Li, X.W. Ran, Clinical effect of ligustrazine combined with citicoline for treatment of diabetic peripheral neuropathy. Zhongguo Zhong Xi Yi Jie He Za Zhi 28, 606–609 (2008)
26. H. Gul, O. Yildiz, A. Dogrul, O. Yesilyurt, A. Isimer, The interaction between IL-1beta and morphine: possible mechanism of the deficiency of morphine-induced analgesia in diabetic mice. Pain 89, 39–45 (2000)
27. V. Tiwari, A. Kuhad, K. Chopra, Emblica officinalis corrects functional, biochemical and molecular deficits in experimental diabetic neuropathy by targeting the oxido-nitrosative stress mediated inflammatory cascade. Phytother. Res. 25, 1527–1536 (2011)
28. A. Kuhad, K. Chopra, Tocotrienol attenuates oxidative-nitrosative stress and inflammatory cascade in experimental model of diabetic neuropathy. Neuropharmacology 57, 456–462 (2009)
29. V. Tiwari, A. Kuhad, K. Chopra, Tocotrienol ameliorates behavioral and biochemical alterations in the rat model of alcoholic neuropathy. Pain 145, 129–135 (2009)
30. K. Arai, S. Maguchi, S. Fujii, H. Ishibashi, K. Oikawa et al., Glycation and inactivation of human Cu-Zn-superoxide dismutase. Identification of the in vitro glycated sites. J. Biol. Chem. 262, 16969–16972 (1987)
31. X.P. Cui, B.Y. Li, H.Q. Gao, N. Wei, W.L. Wang et al., Effects of grape seed proanthocyanidin extracts on peripheral nerves in streptozocin-induced diabetic rats. J. Nutr. Sci. Vitaminol. (Tokyo) 54, 321–328 (2008)
32. J.C. Ansquer, C. Foucher, P. Aubonnet, K. Le Malicot, Fibrates and microvascular complications in diabetes–insight from the FIELD study. Curr. Pharm. Des. 15, 537–552 (2009)
33. G. Chinetti, J.C. Fruchart, B. Staels, Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation. Inflamm. Res. 49, 497–505 (2000)