메뉴 건너뛰기




Volumn 5, Issue 6, 2015, Pages 559-582

Molecular imaging of apoptosis: From micro to macro

Author keywords

Apoptosis; Clinical translation; Macroscopic imaging probes; Microscopic imaging assays

Indexed keywords

2,2',2'' (1,4,7 TRIAZACYCLONONANE 1,4,7 TRIYL)TRIACETIC ACID; 4 (5 DIMETHYLAMINO NAPHTHALENE 1 SULFONAMIDO) 3 (4 IODOPHENYL)BUTANOIC ACID; 4,5 BIS(THIOACETAMIDO)PENTANOYL ANNEXIN 5 TC 99M; CASPASE; FLUORESCENT DYE; GADOLINIUM CHELATE; GADOLINIUM PENTETATE; GADOLINIUM PENTETATE BIS(STEARYLAMIDE); GADOTERIC ACID; HYDRAZIONONICOTINAMIDE ANNEXIN 5 TC 99M; HYDRAZIONONICOTINAMIDE LACTADHERIN TC 99M; LANCOVUTIDE; LIPOCORTIN 5; LIPOCORTIN 5 F 18; N SUCCINIMIDYL 4 FLUOROBENZOATE F 18; N [4 [(4 FLUOROBENZYLIDENE)AMINOOXY]BUTYL]MALEIMIDE F 18; NANOPARTICLE; PENTETIC ACID; RADIOPHARMACEUTICAL AGENT; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; TETRAXETAN; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN;

EID: 84930661848     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.11548     Document Type: Review
Times cited : (94)

References (223)
  • 1
    • 0015383455 scopus 로고
    • Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer. 1972; 26: 239-57.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 2
    • 3442886811 scopus 로고    scopus 로고
    • The pathophysiology of mitochondrial cell death
    • Green DR, Kroemer G. The pathophysiology of mitochondrial cell death. Science. 2004; 305: 626-9.
    • (2004) Science , vol.305 , pp. 626-629
    • Green, D.R.1    Kroemer, G.2
  • 3
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell. 2008; 132: 27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 4
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature. 2006; 444: 756-60.
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5    Hjelmeland, A.B.6
  • 5
    • 58149176735 scopus 로고    scopus 로고
    • New two-photon activated photodynamic therapy sensitizers induce xenograft tumor regressions after near-IR laser treatment through the body of the host mouse
    • Starkey JR, Rebane AK, Drobizhev MA, Meng F, Gong A, Elliott A, et al. New two-photon activated photodynamic therapy sensitizers induce xenograft tumor regressions after near-IR laser treatment through the body of the host mouse. Clin Cancer Res. 2008; 14: 6564-73.
    • (2008) Clin Cancer Res , vol.14 , pp. 6564-6573
    • Starkey, J.R.1    Rebane, A.K.2    Drobizhev, M.A.3    Meng, F.4    Gong, A.5    Elliott, A.6
  • 6
    • 77951134107 scopus 로고    scopus 로고
    • Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis
    • Zhang L, Ren X, Alt E, Bai X, Huang S, Xu Z, et al. Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis. Nature. 2010; 464:1058-61.
    • (2010) Nature. , vol.464 , pp. 1058-1061
    • Zhang, L.1    Ren, X.2    Alt, E.3    Bai, X.4    Huang, S.5    Xu, Z.6
  • 7
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: signaling and modulation
    • Ashkenazi A, Dixit VM. Death receptors: signaling and modulation. Science. 1998; 281: 1305-8.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 8
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO. The biochemistry of apoptosis. Nature. 2000; 407: 770-6.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 9
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol. 2007; 8: 519-29.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 10
    • 79952264011 scopus 로고    scopus 로고
    • Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
    • Tabas I, Ron D. Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat Cell Biol. 2011; 13: 184-90.
    • (2011) Nat Cell Biol , vol.13 , pp. 184-190
    • Tabas, I.1    Ron, D.2
  • 11
    • 0035433420 scopus 로고    scopus 로고
    • Four deaths and a funeral: from caspases to alternative mechanisms
    • Leist M, Jäättelä M. Four deaths and a funeral: from caspases to alternative mechanisms. Nat Rev Mol Cell Biol. 2001; 2: 589-98.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 589-598
    • Leist, M.1    Jäättelä, M.2
  • 13
    • 81255195542 scopus 로고    scopus 로고
    • Programmed necrosis: backup to and competitor with apoptosis in the immune system
    • Han J, Zhong C, Zhang D. Programmed necrosis: backup to and competitor with apoptosis in the immune system. Nat Immunol. 2011; 12: 1143-9.
    • (2011) Nat Immunol , vol.12 , pp. 1143-1149
    • Han, J.1    Zhong, C.2    Zhang, D.3
  • 14
    • 84862006553 scopus 로고    scopus 로고
    • Dysregulation of TNFα-induced necroptotic signaling in chronic lymphocytic leukemia: suppression of CYLD gene by LEF1
    • Liu P, Xu B, Shen W, Zhu H, Wu W, Fu Y, et al. Dysregulation of TNFα-induced necroptotic signaling in chronic lymphocytic leukemia: suppression of CYLD gene by LEF1. Leukemia. 2012; 26: 1293-300.
    • (2012) Leukemia , vol.26 , pp. 1293-1300
    • Liu, P.1    Xu, B.2    Shen, W.3    Zhu, H.4    Wu, W.5    Fu, Y.6
  • 15
    • 0032879583 scopus 로고    scopus 로고
    • Molecular imaging: exploring the next frontier
    • Weissleder R. Molecular imaging: exploring the next frontier. Radiology. 1999; 212: 609-14.
    • (1999) Radiology , vol.212 , pp. 609-614
    • Weissleder, R.1
  • 16
    • 0036083696 scopus 로고    scopus 로고
    • Annexins: from structure to function
    • Gerke V, Moss SE. Annexins: from structure to function. Physiol Rev. 2002; 82:331-71.
    • (2002) Physiol Rev. , vol.82 , pp. 331-371
    • Gerke, V.1    Moss, S.E.2
  • 17
    • 0035782667 scopus 로고    scopus 로고
    • Trimers, dimers of trimers, and trimers of trimers are common building blocks of annexin a5 two-dimensional crystals
    • Oling F, Bergsma-Schutter W, Brisson A. Trimers, dimers of trimers, and trimers of trimers are common building blocks of annexin a5 two-dimensional crystals. J Struct Biol. 2001; 133: 55-63.
    • (2001) J Struct Biol , vol.133 , pp. 55-63
    • Oling, F.1    Bergsma-Schutter, W.2    Brisson, A.3
  • 20
    • 74049146349 scopus 로고    scopus 로고
    • Engineering a polarity-sensitive biosensor for time-lapse imaging of apoptotic processes and degeneration
    • Kim YE, Chen J, Chan JR, Langen R. Engineering a polarity-sensitive biosensor for time-lapse imaging of apoptotic processes and degeneration. Nat Methods. 2010; 7: 67-73.
    • (2010) Nat Methods , vol.7 , pp. 67-73
    • Kim, Y.E.1    Chen, J.2    Chan, J.R.3    Langen, R.4
  • 21
    • 77955216064 scopus 로고    scopus 로고
    • Monitoring apoptosis and neuronal degeneration by real-time detection of phosphatidylserine externalization using a polarity-sensitive indicator of viability and apoptosis
    • Kim YE, Chen J, Langen R, Chan JR. Monitoring apoptosis and neuronal degeneration by real-time detection of phosphatidylserine externalization using a polarity-sensitive indicator of viability and apoptosis. Nat Protoc. 2010; 5: 1396-405.
    • (2010) Nat Protoc , vol.5 , pp. 1396-1405
    • Kim, Y.E.1    Chen, J.2    Langen, R.3    Chan, J.R.4
  • 22
    • 80052837010 scopus 로고    scopus 로고
    • Neuronal deletion of caspase 8 protects against brain injury in mouse models of controlled cortical impact and kainic acid-induced excitotoxicity
    • Krajewska M, You Z, Rong J, Kress C, Huang X, Yang J, et al. Neuronal deletion of caspase 8 protects against brain injury in mouse models of controlled cortical impact and kainic acid-induced excitotoxicity. PLoS One. 2011; 6:24341.
    • (2011) PLoS One , vol.6 , pp. 24341
    • Krajewska, M.1    You, Z.2    Rong, J.3    Kress, C.4    Huang, X.5    Yang, J.6
  • 23
  • 24
    • 46749088244 scopus 로고    scopus 로고
    • DEVD-NucView488: a novel class of enzyme substrates for real-time detection of caspase-3 activity in live cells
    • Cen H, Mao F, Aronchik I, Fuentes RJ, Firestone GL. DEVD-NucView488: a novel class of enzyme substrates for real-time detection of caspase-3 activity in live cells. FASEB J. 2008; 22: 2243-52.
    • (2008) FASEB J , vol.22 , pp. 2243-2252
    • Cen, H.1    Mao, F.2    Aronchik, I.3    Fuentes, R.J.4    Firestone, G.L.5
  • 25
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR, Reed JC. Mitochondria and apoptosis. Science. 1998; 281: 1309-12.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 26
    • 0027374638 scopus 로고
    • A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1)
    • Cossarizza A, Baccarani-Contri M, Kalashnikova G, Franceschi C. A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1). Biochem Biophys Res Commun. 1993; 197: 40-5.
    • (1993) Biochem Biophys Res Commun , vol.197 , pp. 40-45
    • Cossarizza, A.1    Baccarani-Contri, M.2    Kalashnikova, G.3    Franceschi, C.4
  • 27
    • 0030612749 scopus 로고    scopus 로고
    • JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis
    • Salvioli S, Ardizzoni A, Franceschi C, Cossarizza A. JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett. 1997; 411: 77-82.
    • (1997) FEBS Lett , vol.411 , pp. 77-82
    • Salvioli, S.1    Ardizzoni, A.2    Franceschi, C.3    Cossarizza, A.4
  • 28
    • 0025806764 scopus 로고
    • Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1
    • Smiley ST, Reers M, Mottola-Hartshorn C, Lin M, Chen A, Smith TW, et al. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci U S A. 1991; 88: 3671-5.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 3671-3675
    • Smiley, S.T.1    Reers, M.2    Mottola-Hartshorn, C.3    Lin, M.4    Chen, A.5    Smith, T.W.6
  • 32
    • 0027269557 scopus 로고
    • Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays
    • Gorczyca W, Gong J, Darzynkiewicz Z. Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res. 1993; 53: 1945-51.
    • (1993) Cancer Res , vol.53 , pp. 1945-1951
    • Gorczyca, W.1    Gong, J.2    Darzynkiewicz, Z.3
  • 34
    • 51049094897 scopus 로고    scopus 로고
    • Cu-catalyzed azide-alkyne cycloaddition
    • Meldal M, Tornøe CW. Cu-catalyzed azide-alkyne cycloaddition. Chem Rev. 2008; 108: 2952-3015.
    • (2008) Chem Rev , vol.108 , pp. 2952-3015
    • Meldal, M.1    Tornøe, C.W.2
  • 35
    • 40649111377 scopus 로고    scopus 로고
    • A chemical method for fast and sensitive detection of DNA synthesis in vivo
    • Salic A, Mitchison TJ. A chemical method for fast and sensitive detection of DNA synthesis in vivo. Proc Natl Acad Sci U S A. 2008; 105: 2415-20.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2415-2420
    • Salic, A.1    Mitchison, T.J.2
  • 37
    • 33644977266 scopus 로고    scopus 로고
    • Apo-Sense: a novel technology for functional molecular imaging of cell death in models of acute renal tubular necrosis
    • Damianovich M, Ziv I, Heyman SN, Rosen S, Shina A, Kidron D, et al. Apo-Sense: a novel technology for functional molecular imaging of cell death in models of acute renal tubular necrosis. Eur J Nucl Med Mol Imaging. 2006; 33:281-91.
    • (2006) Eur J Nucl Med Mol Imaging. , vol.33 , pp. 281-291
    • Damianovich, M.1    Ziv, I.2    Heyman, S.N.3    Rosen, S.4    Shina, A.5    Kidron, D.6
  • 39
    • 26944451271 scopus 로고    scopus 로고
    • Molecular imaging of apoptosis in cancer
    • Hakumäki JM, Liimatainen T. Molecular imaging of apoptosis in cancer. Eur J Radiol. 2005; 56: 143-53.
    • (2005) Eur J Radiol , vol.56 , pp. 143-153
    • Hakumäki, J.M.1    Liimatainen, T.2
  • 40
    • 84894625002 scopus 로고    scopus 로고
    • Radiolabeling strategies for tumor-targeting proteinaceous drugs
    • Sugiura G, Kühn H, Sauter M, Haberkorn U, Mier W. Radiolabeling strategies for tumor-targeting proteinaceous drugs. Molecules. 2014; 19: 2135-65.
    • (2014) Molecules , vol.19 , pp. 2135-2165
    • Sugiura, G.1    Kühn, H.2    Sauter, M.3    Haberkorn, U.4    Mier, W.5
  • 42
    • 77952473782 scopus 로고    scopus 로고
    • Peptides and peptide hormones for molecular imaging and disease diagnosis
    • Lee S, Xie J, Chen X. Peptides and peptide hormones for molecular imaging and disease diagnosis. Chem Rev. 2010; 110: 3087-111.
    • (2010) Chem Rev , vol.110 , pp. 3087-3111
    • Lee, S.1    Xie, J.2    Chen, X.3
  • 45
    • 44849095832 scopus 로고    scopus 로고
    • Preliminary in vivo evaluation of a novel 99mTc-labeled HYNIC-cys-annexin A5 as an apoptosis imaging agent
    • Fonge H, de Saint Hubert M, Vunckx K, Rattat D, Nuyts J, Bormans G, et al. Preliminary in vivo evaluation of a novel 99mTc-labeled HYNIC-cys-annexin A5 as an apoptosis imaging agent. Bioorg Med Chem Lett. 2008; 18: 3794-8.
    • (2008) Bioorg Med Chem Lett , vol.18 , pp. 3794-3798
    • Fonge, H.1    de Saint Hubert, M.2    Vunckx, K.3    Rattat, D.4    Nuyts, J.5    Bormans, G.6
  • 46
    • 31844440437 scopus 로고    scopus 로고
    • Evaluation of 99mTc-MAG3-annexin A5: influence of the chelate on in vitro and in vivo properties in mice
    • Vanderheyden JL, Liu G, He J, Patel B, Tait JF, Hnatowich DJ. Evaluation of 99mTc-MAG3-annexin A5: influence of the chelate on in vitro and in vivo properties in mice. Nucl Med Biol. 2006; 33: 135-44.
    • (2006) Nucl Med Biol , vol.33 , pp. 135-144
    • Vanderheyden, J.L.1    Liu, G.2    He, J.3    Patel, B.4    Tait, J.F.5    Hnatowich, D.J.6
  • 47
    • 0035085331 scopus 로고    scopus 로고
    • In vivo and in vitro measurement of apoptosis in breast cancer cells using 99mTc-EC-annexin V
    • Yang DJ, Azhdarinia A, Wu P, Yu DF, Tansey W, Kalimi SK, et al. In vivo and in vitro measurement of apoptosis in breast cancer cells using 99mTc-EC-annexin V. Cancer Biother Radiopharm. 2001; 16: 73-83.
    • (2001) Cancer Biother Radiopharm , vol.16 , pp. 73-83
    • Yang, D.J.1    Azhdarinia, A.2    Wu, P.3    Yu, D.F.4    Tansey, W.5    Kalimi, S.K.6
  • 48
    • 0033645434 scopus 로고    scopus 로고
    • Development and characterization of annexin V mutants with endogenous chelation sites for 99mTc
    • Tait JF, Brown DS, Gibson DF, Blankenberg FG, Strauss HW. Development and characterization of annexin V mutants with endogenous chelation sites for 99mTc. Bioconjug Chem. 2000; 11: 918-25.
    • (2000) Bioconjug Chem , vol.11 , pp. 918-925
    • Tait, J.F.1    Brown, D.S.2    Gibson, D.F.3    Blankenberg, F.G.4    Strauss, H.W.5
  • 49
    • 0036740090 scopus 로고    scopus 로고
    • Development of annexin V mutants suitable for labeling with Tc(I)-carbonyl complex
    • Tait JF, Smith C, Gibson DF. Development of annexin V mutants suitable for labeling with Tc(I)-carbonyl complex. Bioconjug Chem. 2002; 13: 1119-23.
    • (2002) Bioconjug Chem , vol.13 , pp. 1119-1123
    • Tait, J.F.1    Smith, C.2    Gibson, D.F.3
  • 50
    • 0242665459 scopus 로고    scopus 로고
    • Improved radiolabeling of PEGylated protein: PEGylated annexin V for noninvasive imaging of tumor apoptosis
    • Wen X, Wu QP, Ke S, Wallace S, Charnsangavej C, Huang P, et al. Improved radiolabeling of PEGylated protein: PEGylated annexin V for noninvasive imaging of tumor apoptosis. Cancer Biother Radiopharm. 2003; 18: 819-27.
    • (2003) Cancer Biother Radiopharm , vol.18 , pp. 819-827
    • Wen, X.1    Wu, Q.P.2    Ke, S.3    Wallace, S.4    Charnsangavej, C.5    Huang, P.6
  • 51
    • 1842592126 scopus 로고    scopus 로고
    • Imaging taxane-induced tumor apoptosis using PEGylated, 111In-labeled annexin V
    • Ke S, Wen X, Wu QP, Wallace S, Charnsangavej C, Stachowiak AM, et al. Imaging taxane-induced tumor apoptosis using PEGylated, 111In-labeled annexin V. J Nucl Med 2004; 45: 108-15.
    • (2004) J Nucl Med , vol.45 , pp. 108-115
    • Ke, S.1    Wen, X.2    Wu, Q.P.3    Wallace, S.4    Charnsangavej, C.5    Stachowiak, A.M.6
  • 55
    • 16844369263 scopus 로고    scopus 로고
    • MBP-annexin A5 radiolabelled directly with iodine-124 can be used to image apoptosis in vivo using PET
    • Dekker B, Keen H, Lyons S, Disley L, Hastings D, Reader A, et al. MBP-annexin A5 radiolabelled directly with iodine-124 can be used to image apoptosis in vivo using PET. Nucl Med Biol. 2005; 32: 241-52.
    • (2005) Nucl Med Biol , vol.32 , pp. 241-252
    • Dekker, B.1    Keen, H.2    Lyons, S.3    Disley, L.4    Hastings, D.5    Reader, A.6
  • 56
    • 33846408353 scopus 로고    scopus 로고
    • PET imaging of apoptosis with 64Cu-labeled streptavidin following pretargeting of phosphatidylserine with biotinylated annexin-V
    • Cauchon N, Langlois R, Rousseau JA, Tessier G, Cadorette J, Lecomte R, et al. PET imaging of apoptosis with 64Cu-labeled streptavidin following pretargeting of phosphatidylserine with biotinylated annexin-V. Eur J Nucl Med Mol Imaging. 2007; 34: 247-58.
    • (2007) Eur J Nucl Med Mol Imaging , vol.34 , pp. 247-258
    • Cauchon, N.1    Langlois, R.2    Rousseau, J.A.3    Tessier, G.4    Cadorette, J.5    Lecomte, R.6
  • 57
    • 84864752361 scopus 로고    scopus 로고
    • Combining [11C]-AnxA5 PET imaging with serum biomarkers for improved detection in live mice of modest cell death in human solid tumor xenografts
    • Cheng Q, Lu L, Grafström J, Olofsson MH, Thorell JO, Samén E, et al. Combining [11C]-AnxA5 PET imaging with serum biomarkers for improved detection in live mice of modest cell death in human solid tumor xenografts. PLoS One. 2012; 7: 42151.
    • (2012) PLoS One , vol.7 , pp. 42151
    • Cheng, Q.1    Lu, L.2    Grafström, J.3    Olofsson, M.H.4    Thorell, J.O.5    Samén, E.6
  • 58
    • 84872826265 scopus 로고    scopus 로고
    • Site-specifically 11C-labeled Sel-tagged annexin A5 and a size-matched control for dynamic in vivo PET imaging of protein distribution in tissues prior to and after induced cell death
    • Cheng Q, Lu L, Grafström J, Olofsson MH, Thorell JO, Samén E, et al. Site-specifically 11C-labeled Sel-tagged annexin A5 and a size-matched control for dynamic in vivo PET imaging of protein distribution in tissues prior to and after induced cell death. Biochim Biophys Acta. 2013; 1830: 2562-73.
    • (2013) Biochim Biophys Acta , vol.1830 , pp. 2562-2573
    • Cheng, Q.1    Lu, L.2    Grafström, J.3    Olofsson, M.H.4    Thorell, J.O.5    Samén, E.6
  • 59
    • 79954586796 scopus 로고    scopus 로고
    • Evaluation of chemotherapy response in VX2 rabbit lung cancer with 18F-labeled C2A domain of synaptotagmin I
    • Wang F, Fang W, Zhang MR, Zhao M, Liu B, Wang Z, et al. Evaluation of chemotherapy response in VX2 rabbit lung cancer with 18F-labeled C2A domain of synaptotagmin I. J Nucl Med. 2011; 52: 592-9.
    • (2011) J Nucl Med , vol.52 , pp. 592-599
    • Wang, F.1    Fang, W.2    Zhang, M.R.3    Zhao, M.4    Liu, B.5    Wang, Z.6
  • 60
    • 33749049365 scopus 로고    scopus 로고
    • 99mTc-labeled C2A domain of synaptotagmin I as a target-specific molecular probe for noninvasive imaging of acute myocardial infarction
    • Zhao M, Zhu X, Ji S, Zhou J, Ozker KS, Fang W, et al. 99mTc-labeled C2A domain of synaptotagmin I as a target-specific molecular probe for noninvasive imaging of acute myocardial infarction. J Nucl Med. 2006; 47: 1367-74.
    • (2006) J Nucl Med , vol.47 , pp. 1367-1374
    • Zhao, M.1    Zhu, X.2    Ji, S.3    Zhou, J.4    Ozker, K.S.5    Fang, W.6
  • 61
    • 34248643724 scopus 로고    scopus 로고
    • Preparation and in vitro evaluation of 99mTc-labelled bovine lactadherin as a novel radioligand for apoptosis detection
    • Waehrens LN, Rasmussen JT, Heegaard CW, Falborg L. Preparation and in vitro evaluation of 99mTc-labelled bovine lactadherin as a novel radioligand for apoptosis detection. J Label Compd Radiopharm. 2007; 50: 211-17.
    • (2007) J Label Compd Radiopharm , vol.50 , pp. 211-217
    • Waehrens, L.N.1    Rasmussen, J.T.2    Heegaard, C.W.3    Falborg, L.4
  • 66
    • 18244408264 scopus 로고    scopus 로고
    • Annexin-V imaging for noninvasive detection of cardiac allograft rejection
    • Narula J, Acio ER, Narula N, Samuels LE, Fyfe B, Wood D, et al. Annexin-V imaging for noninvasive detection of cardiac allograft rejection. Nat Med. 2001; 7: 1347-52.
    • (2001) Nat Med , vol.7 , pp. 1347-1352
    • Narula, J.1    Acio, E.R.2    Narula, N.3    Samuels, L.E.4    Fyfe, B.5    Wood, D.6
  • 69
    • 0025602549 scopus 로고
    • Technetium-99m-human polyclonal IgG radiolabeled via the hydrazino nicotinamide derivative for imaging focal sites of infection in rats
    • Abrams MJ, Juweid M, tenKate CI, Schwartz DA, Hauser MM, Gaul FE, et al. Technetium-99m-human polyclonal IgG radiolabeled via the hydrazino nicotinamide derivative for imaging focal sites of infection in rats. J Nucl Med. 1990; 31: 2022-8.
    • (1990) J Nucl Med , vol.31 , pp. 2022-2028
    • Abrams, M.J.1    Juweid, M.2    tenKate, C.I.3    Schwartz, D.A.4    Hauser, M.M.5    Gaul, F.E.6
  • 71
    • 0036717347 scopus 로고    scopus 로고
    • Increased uptake of the apoptosis-imaging agent 99mTc recombinant human Annexin V in human tumors after one course of chemotherapy as a predictor of tumor response and patient prognosis
    • Belhocine T, Steinmetz N, Hustinx R, Bartsch P, Jerusalem G, Seidel L, et al. Increased uptake of the apoptosis-imaging agent 99mTc recombinant human Annexin V in human tumors after one course of chemotherapy as a predictor of tumor response and patient prognosis. Clin Cancer Res. 2002; 8: 2766-74.
    • (2002) Clin Cancer Res , vol.8 , pp. 2766-2774
    • Belhocine, T.1    Steinmetz, N.2    Hustinx, R.3    Bartsch, P.4    Jerusalem, G.5    Seidel, L.6
  • 72
    • 0037487013 scopus 로고    scopus 로고
    • Safety, biodistribution, and dosimetry of 99mTc-HYNIC-annexin V, a novel human recombinant annexin V for human application
    • Kemerink GJ, Liu X, Kieffer D, Ceyssens S, Mortelmans L, Verbruggen AM, et al. Safety, biodistribution, and dosimetry of 99mTc-HYNIC-annexin V, a novel human recombinant annexin V for human application. J Nucl Med. 2003; 44:947-52.
    • (2003) J Nucl Med. , vol.44 , pp. 947-952
    • Kemerink, G.J.1    Liu, X.2    Kieffer, D.3    Ceyssens, S.4    Mortelmans, L.5    Verbruggen, A.M.6
  • 73
    • 43349087385 scopus 로고    scopus 로고
    • 99mTc Hynic-rh-Annexin V scintigraphy for in vivo imaging of apoptosis in patients with head and neck cancer treated with chemoradiotherapy
    • Hoebers FJ, Kartachova M, de Bois J, van den Brekel MW, van Tinteren H, van Herk M, et al. 99mTc Hynic-rh-Annexin V scintigraphy for in vivo imaging of apoptosis in patients with head and neck cancer treated with chemoradiotherapy. Eur J Nucl Med Mol Imaging. 2008; 35: 509-18.
    • (2008) Eur J Nucl Med Mol Imaging , vol.35 , pp. 509-518
    • Hoebers, F.J.1    Kartachova, M.2    de Bois, J.3    van den Brekel, M.W.4    van Tinteren, H.5    van Herk, M.6
  • 74
    • 69249213017 scopus 로고    scopus 로고
    • Influence of chemotherapy on the biodistribution of [99mTc]hydrazinonicotinamide annexin V in cancer patients
    • Rottey S, van den Bossche B, Slegers G, Van Belle S, van de Wiele C. Influence of chemotherapy on the biodistribution of [99mTc]hydrazinonicotinamide annexin V in cancer patients. Q J Nucl Med Mol Imaging. 2009; 53: 127-32.
    • (2009) Q J Nucl Med Mol Imaging , vol.53 , pp. 127-132
    • Rottey, S.1    van den Bossche, B.2    Slegers, G.3    Van Belle, S.4    van de Wiele, C.5
  • 75
    • 34447253819 scopus 로고    scopus 로고
    • Prognostic significance of 99mTc Hynic-rh-annexin V scintigraphy during platinum-based chemotherapy in advanced lung cancer
    • Kartachova M, van Zandwijk N, Burgers S, van Tinteren H, Verheij M, Valdés Olmos RA. Prognostic significance of 99mTc Hynic-rh-annexin V scintigraphy during platinum-based chemotherapy in advanced lung cancer. J Clin Oncol. 2007; 25: 2534-9.
    • (2007) J Clin Oncol , vol.25 , pp. 2534-2539
    • Kartachova, M.1    van Zandwijk, N.2    Burgers, S.3    van Tinteren, H.4    Verheij, M.5    Valdés Olmos, R.A.6
  • 76
    • 39149109322 scopus 로고    scopus 로고
    • 99mTc-HYNIC-rh-annexin-V scintigraphy: visual and quantitative evaluation of early treatment-induced apoptosis to predict treatment outcome
    • Kartachova MS, Valdés Olmos RA, Haas RL, Hoebers FJ, Herk M, Verheij M. 99mTc-HYNIC-rh-annexin-V scintigraphy: visual and quantitative evaluation of early treatment-induced apoptosis to predict treatment outcome. Nucl Med Commun. 2008; 29: 39-44.
    • (2008) Nucl Med Commun , vol.29 , pp. 39-44
    • Kartachova, M.S.1    Valdés Olmos, R.A.2    Haas, R.L.3    Hoebers, F.J.4    Herk, M.5    Verheij, M.6
  • 77
    • 84879647030 scopus 로고    scopus 로고
    • Preliminary biological evaluation of novel 99mTc-Cys-annexin A5 as a apoptosis imaging agent
    • Lu C, Jiang Q, Hu M, Tan C, Ji Y, Yu H, et al. Preliminary biological evaluation of novel 99mTc-Cys-annexin A5 as a apoptosis imaging agent. Molecules. 2013; 18: 6908-18.
    • (2013) Molecules , vol.18 , pp. 6908-6918
    • Lu, C.1    Jiang, Q.2    Hu, M.3    Tan, C.4    Ji, Y.5    Yu, H.6
  • 78
    • 84929504630 scopus 로고    scopus 로고
    • Preclinical validation of 99mTc-annexin A5-128 in experimental autoimmune myocarditis and infective endocarditis: comparison with 99mTc-HYNIC-annexin A5
    • Benali K, Louedec L, Azzouna RB, Merceron O, Nassar P, Al Shoukr F, et al. Preclinical validation of 99mTc-annexin A5-128 in experimental autoimmune myocarditis and infective endocarditis: comparison with 99mTc-HYNIC-annexin A5. Mol Imaging. 2014; 13: 1-10.
    • (2014) Mol Imaging , vol.13 , pp. 1-10
    • Benali, K.1    Louedec, L.2    Azzouna, R.B.3    Merceron, O.4    Nassar, P.5    Al Shoukr, F.6
  • 79
    • 33745842886 scopus 로고    scopus 로고
    • 99mTc-labeled annexin V fragments: a potential SPECT radiopharmaceutical for imaging cell death
    • Mukherjee A, Kothari K, Tóth G, Szemenyei E, Sarma HD, Környei J, et al. 99mTc-labeled annexin V fragments: a potential SPECT radiopharmaceutical for imaging cell death. Nucl Med Biol. 2006; 33: 635-43.
    • (2006) Nucl Med Biol , vol.33 , pp. 635-643
    • Mukherjee, A.1    Kothari, K.2    Tóth, G.3    Szemenyei, E.4    Sarma, H.D.5    Környei, J.6
  • 80
  • 81
    • 19644391013 scopus 로고    scopus 로고
    • Evaluation of 18F-annexin V as a PET imaging agent in an animal model of apoptosis
    • Yagle KJ, Eary JF, Tait JF, Grierson JR, Link JM, Lewellen B, et al. Evaluation of 18F-annexin V as a PET imaging agent in an animal model of apoptosis. J Nucl Med. 2005; 46: 658-66.
    • (2005) J Nucl Med , vol.46 , pp. 658-666
    • Yagle, K.J.1    Eary, J.F.2    Tait, J.F.3    Grierson, J.R.4    Link, J.M.5    Lewellen, B.6
  • 83
    • 84870455411 scopus 로고    scopus 로고
    • Longitudinal PET imaging of doxorubicin-induced cell death with 18F-Annexin V
    • Hu S, Kiesewetter DO, Zhu L, Guo N, Gao H, Liu G, et al. Longitudinal PET imaging of doxorubicin-induced cell death with 18F-Annexin V. Mol Imaging Biol. 2012; 14: 762-70.
    • (2012) Mol Imaging Biol , vol.14 , pp. 762-770
    • Hu, S.1    Kiesewetter, D.O.2    Zhu, L.3    Guo, N.4    Gao, H.5    Liu, G.6
  • 85
  • 86
    • 79952776184 scopus 로고    scopus 로고
    • Peptide-based imaging agents targeting phosphatidylserine for the detection of apoptosis
    • Xiong C, Brewer K, Song S, Zhang R, Lu W, Wen X, et al. Peptide-based imaging agents targeting phosphatidylserine for the detection of apoptosis. J Med Chem. 2011; 54: 1825-35.
    • (2011) J Med Chem , vol.54 , pp. 1825-1835
    • Xiong, C.1    Brewer, K.2    Song, S.3    Zhang, R.4    Lu, W.5    Wen, X.6
  • 87
    • 84872028876 scopus 로고    scopus 로고
    • Apoptosis imaging probe predicts early chemotherapy response in preclinical models: A comparative study with 18F-FDG PET
    • Song S, Xiong C, Lu W, Ku G, Huang G, Li C. Apoptosis imaging probe predicts early chemotherapy response in preclinical models: A comparative study with 18F-FDG PET. J Nucl Med. 2013; 54: 104-10.
    • (2013) J Nucl Med , vol.54 , pp. 104-110
    • Song, S.1    Xiong, C.2    Lu, W.3    Ku, G.4    Huang, G.5    Li, C.6
  • 88
    • 52049088939 scopus 로고    scopus 로고
    • Coincident exposure of phosphatidylethanolamine and anionic phospholipids on the surface of irradiated cells
    • Marconescu A, Thorpe PE. Coincident exposure of phosphatidylethanolamine and anionic phospholipids on the surface of irradiated cells. Biochim Biophys Acta. 2008; 1778: 2217-24.
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 2217-2224
    • Marconescu, A.1    Thorpe, P.E.2
  • 89
    • 48749103305 scopus 로고    scopus 로고
    • 99mTc-labeled duramycin as a novel phosphatidylethanolamine-binding molecular probe
    • Zhao M, Li Z, Bugenhagen S. 99mTc-labeled duramycin as a novel phosphatidylethanolamine-binding molecular probe. J Nucl Med. 2008; 49: 1345-52.
    • (2008) J Nucl Med , vol.49 , pp. 1345-1352
    • Zhao, M.1    Li, Z.2    Bugenhagen, S.3
  • 90
    • 84881462388 scopus 로고    scopus 로고
    • Whole-body imaging of high-dose ionizing irradiation-induced tissue injuries using 99mTc-duramycin
    • Johnson SE, Li Z, Liu Y, Moulder JE, Zhao M. Whole-body imaging of high-dose ionizing irradiation-induced tissue injuries using 99mTc-duramycin. J Nucl Med. 2013; 54: 1397-403.
    • (2013) J Nucl Med , vol.54 , pp. 1397-1403
    • Johnson, S.E.1    Li, Z.2    Liu, Y.3    Moulder, J.E.4    Zhao, M.5
  • 92
    • 84866008259 scopus 로고    scopus 로고
    • A single-step kit formulation for the 99mTc-labeling of HYNIC-Duramycin
    • Zhao M, Li Z. A single-step kit formulation for the 99mTc-labeling of HYNIC-Duramycin. Nucl Med Biol. 2012; 39: 1006-11.
    • (2012) Nucl Med Biol , vol.39 , pp. 1006-1011
    • Zhao, M.1    Li, Z.2
  • 93
    • 49949087224 scopus 로고    scopus 로고
    • Caspase-mediated changes in histone H1 in early apoptosis: prolonged caspase activation in developing olfactory sensory neurons
    • Ohsawa S, Hamada S, Yoshida H, Miura M. Caspase-mediated changes in histone H1 in early apoptosis: prolonged caspase activation in developing olfactory sensory neurons. Cell Death Differ. 2008; 15: 1429-39.
    • (2008) Cell Death Differ , vol.15 , pp. 1429-1439
    • Ohsawa, S.1    Hamada, S.2    Yoshida, H.3    Miura, M.4
  • 95
    • 0034802796 scopus 로고    scopus 로고
    • Investigation of a potential scintigraphic marker of apoptosis: radioiodinated Z-Val-Ala-DL-Asp(O-methyl)-fluoromethyl ketone
    • Haberkorn U, Kinscherf R, Krammer PH, Mier M, Eisenhut M. Investigation of a potential scintigraphic marker of apoptosis: radioiodinated Z-Val-Ala-DL-Asp(O-methyl)-fluoromethyl ketone. Nucl Med Biol. 2001; 28:793-8.
    • (2001) Nucl Med Biol. , vol.28 , pp. 793-798
    • Haberkorn, U.1    Kinscherf, R.2    Krammer, P.H.3    Mier, M.4    Eisenhut, M.5
  • 98
    • 84890478418 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of the caspase-3 substrate-based radiotracer [18F]-CP18 for PET imaging of apoptosis in tumors
    • Xia CF, Chen G, Gangadharmath U, Gomez LF, Liang Q, Mu F, et al. In vitro and in vivo evaluation of the caspase-3 substrate-based radiotracer [18F]-CP18 for PET imaging of apoptosis in tumors. Mol Imaging Biol. 2013; 15: 748-57.
    • (2013) Mol Imaging Biol , vol.15 , pp. 748-757
    • Xia, C.F.1    Chen, G.2    Gangadharmath, U.3    Gomez, L.F.4    Liang, Q.5    Mu, F.6
  • 99
    • 84893441437 scopus 로고    scopus 로고
    • Biodistribution and radiation dosimetry of 18F-CP-18, a potential apoptosis imaging agent, as determined from PET/CT scans in healthy volunteers
    • Doss M, Kolb HC, Walsh JC, Mocharla V, Fan H, Chaudhary A, et al. Biodistribution and radiation dosimetry of 18F-CP-18, a potential apoptosis imaging agent, as determined from PET/CT scans in healthy volunteers. J Nucl Med. 2013; 54: 2087-92.
    • (2013) J Nucl Med , vol.54 , pp. 2087-2092
    • Doss, M.1    Kolb, H.C.2    Walsh, J.C.3    Mocharla, V.4    Fan, H.5    Chaudhary, A.6
  • 100
    • 84864560649 scopus 로고    scopus 로고
    • Molecular imaging with activatable reporter systems
    • Niu G, Chen X. Molecular imaging with activatable reporter systems. Theranostics. 2012; 2: 413-23.
    • (2012) Theranostics , vol.2 , pp. 413-423
    • Niu, G.1    Chen, X.2
  • 102
    • 0346147032 scopus 로고    scopus 로고
    • Detection of apoptotic cells using a synthetic fluorescent sensor for membrane surfaces that contain phosphatidylserine
    • Koulov AV, Stucker KA, Lakshmi C, Robinson JP, Smith BD. Detection of apoptotic cells using a synthetic fluorescent sensor for membrane surfaces that contain phosphatidylserine. Cell Death Differ. 2003; 10: 1357-9.
    • (2003) Cell Death Differ , vol.10 , pp. 1357-1359
    • Koulov, A.V.1    Stucker, K.A.2    Lakshmi, C.3    Robinson, J.P.4    Smith, B.D.5
  • 103
    • 22844432854 scopus 로고    scopus 로고
    • New reagents for phosphatidylserine recognition and detection of apoptosis
    • Hanshaw RG, Smith BD. New reagents for phosphatidylserine recognition and detection of apoptosis. Bioorg Med Chem. 2005; 13: 5035-42.
    • (2005) Bioorg Med Chem , vol.13 , pp. 5035-5042
    • Hanshaw, R.G.1    Smith, B.D.2
  • 104
    • 80051546958 scopus 로고    scopus 로고
    • In vivo targeting of cell death using a synthetic fluorescent molecular probe
    • Smith BA, Xiao S, Wolter W, Wheeler J, Suckow MA, Smith BD. In vivo targeting of cell death using a synthetic fluorescent molecular probe. Apoptosis. 2011; 16: 722-31.
    • (2011) Apoptosis , vol.16 , pp. 722-731
    • Smith, B.A.1    Xiao, S.2    Wolter, W.3    Wheeler, J.4    Suckow, M.A.5    Smith, B.D.6
  • 105
  • 106
    • 79957491676 scopus 로고    scopus 로고
    • Synthesis and preliminary evaluation of radiolabeled bis(zinc(II)-dipicolylamine) coordination complexes as cell death imaging agents
    • Wyffels L, Gray BD, Barber C, Moore SK, Woolfenden JM, Pak KY, et al. Synthesis and preliminary evaluation of radiolabeled bis(zinc(II)-dipicolylamine) coordination complexes as cell death imaging agents. Bioorg Med Chem. 2011; 19: 3425-33.
    • (2011) Bioorg Med Chem , vol.19 , pp. 3425-3433
    • Wyffels, L.1    Gray, B.D.2    Barber, C.3    Moore, S.K.4    Woolfenden, J.M.5    Pak, K.Y.6
  • 109
    • 33845364699 scopus 로고    scopus 로고
    • Molecular imaging of cell death in vivo by a novel small molecule probe
    • Aloya R, Shirvan A, Grimberg H, Reshef A, Levin G, Kidron D, et al. Molecular imaging of cell death in vivo by a novel small molecule probe. Apoptosis. 2006; 11: 2089-101.
    • (2006) Apoptosis , vol.11 , pp. 2089-2101
    • Aloya, R.1    Shirvan, A.2    Grimberg, H.3    Reshef, A.4    Levin, G.5    Kidron, D.6
  • 110
    • 33947328557 scopus 로고    scopus 로고
    • Novel molecular imaging of cell death in experimental cerebral stroke
    • Reshef A, Shirvan A, Grimberg H, Levin G, Cohen A, Mayk A, et al. Novel molecular imaging of cell death in experimental cerebral stroke. Brain Res. 2007; 1144: 156-64.
    • (2007) Brain Res , vol.1144 , pp. 156-164
    • Reshef, A.1    Shirvan, A.2    Grimberg, H.3    Levin, G.4    Cohen, A.5    Mayk, A.6
  • 111
    • 34347396757 scopus 로고    scopus 로고
    • Monitoring of chemotherapy-induced cell death in melanoma tumors by N,N'-Didansyl-L-cystine
    • Cohen A, Ziv I, Aloya T, Levin G, Kidron D, Grimberg H, et al. Monitoring of chemotherapy-induced cell death in melanoma tumors by N,N'-Didansyl-L-cystine. Tech Cancer Res T. 2007; 6: 221-34.
    • (2007) Tech Cancer Res T , vol.6 , pp. 221-234
    • Cohen, A.1    Ziv, I.2    Aloya, T.3    Levin, G.4    Kidron, D.5    Grimberg, H.6
  • 112
    • 60649115423 scopus 로고    scopus 로고
    • Monitoring of tumor response to chemotherapy in vivo by a novel small-molecule detector of apoptosis
    • Grimberg H, Levin G, Shirvan A, Cohen A, Reshef A, Ziv I. Monitoring of tumor response to chemotherapy in vivo by a novel small-molecule detector of apoptosis. Apoptosis 2009; 14: 257-67.
    • (2009) Apoptosis , vol.14 , pp. 257-267
    • Grimberg, H.1    Levin, G.2    Shirvan, A.3    Cohen, A.4    Reshef, A.5    Ziv, I.6
  • 113
    • 51349157610 scopus 로고    scopus 로고
    • Molecular imaging of neurovascular cell death in experimental cerebral stroke by PET
    • Reshef A, Shirvan A, Waterhouse RN, Grimberg H, Levin G, Cohen A, et al. Molecular imaging of neurovascular cell death in experimental cerebral stroke by PET. J Nucl Med. 2008; 49: 1520-8.
    • (2008) J Nucl Med , vol.49 , pp. 1520-1528
    • Reshef, A.1    Shirvan, A.2    Waterhouse, R.N.3    Grimberg, H.4    Levin, G.5    Cohen, A.6
  • 115
    • 77956155207 scopus 로고    scopus 로고
    • Apoptosis imaging with PET-18F-ML-10 for early assessment of response of brain metastases to radiotherapy
    • Shirvan A, Reshef A, Allen A, Fenig E, Stenmetz A, Groshar D, et al. Apoptosis imaging with PET-18F-ML-10 for early assessment of response of brain metastases to radiotherapy. J Nucl Med. 2009; 50(Suppl 2): S453.
    • (2009) J Nucl Med , vol.50 , pp. S453
    • Shirvan, A.1    Reshef, A.2    Allen, A.3    Fenig, E.4    Stenmetz, A.5    Groshar, D.6
  • 116
    • 84865656104 scopus 로고    scopus 로고
    • Assessment of response of brain metastases to radiotherapy by PET imaging of apoptosis with 18F-ML-10
    • Allen AM, Ben-Ami M, Reshef A, Steinmetz A, Kundel Y, Inbar E, et al. Assessment of response of brain metastases to radiotherapy by PET imaging of apoptosis with 18F-ML-10. Eur J Nucl Med Mol Imaging. 2012; 39: 1400-8.
    • (2012) Eur J Nucl Med Mol Imaging , vol.39 , pp. 1400-1408
    • Allen, A.M.1    Ben-Ami, M.2    Reshef, A.3    Steinmetz, A.4    Kundel, Y.5    Inbar, E.6
  • 118
    • 84867497719 scopus 로고    scopus 로고
    • Biomarkers and molecular probes for cell death imaging and targeted therapeutics
    • Smith BA, Smith BD. Biomarkers and molecular probes for cell death imaging and targeted therapeutics. Bioconjug Chem. 2012; 23: 1989-2006.
    • (2012) Bioconjug Chem , vol.23 , pp. 1989-2006
    • Smith, B.A.1    Smith, B.D.2
  • 119
    • 73449146098 scopus 로고    scopus 로고
    • Biological evaluation of dansylhydrazone derivatives for cancer cell apoptosis imaging
    • Zeng W, Yao M, Townsend D, Kabalka G, Wall J, Miao W. Biological evaluation of dansylhydrazone derivatives for cancer cell apoptosis imaging. J Nucl Med. 2008; 49(Suppl 1): S351.
    • (2008) J Nucl Med , vol.49 , pp. S351
    • Zeng, W.1    Yao, M.2    Townsend, D.3    Kabalka, G.4    Wall, J.5    Miao, W.6
  • 120
    • 84930621268 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of (E)-5-(dimethylamino)-N'-(4-fluoro-benzylidene)-naphthalene-1-sulfonohydra zide [DFNSH] as an agent for imaging apoptosis
    • Zeng W, Yao M, Townsend D, Kabalka G, Wall J, Lepuil M, et al. Synthesis and biological evaluation of (E)-5-(dimethylamino)-N'-(4-fluoro-benzylidene)-naphthalene-1-sulfonohydra zide [DFNSH] as an agent for imaging apoptosis. J Nucl Med. 2008; 49(Suppl 1): S294.
    • (2008) J Nucl Med , vol.49 , pp. S294
    • Zeng, W.1    Yao, M.2    Townsend, D.3    Kabalka, G.4    Wall, J.5    Lepuil, M.6
  • 121
    • 44649187419 scopus 로고    scopus 로고
    • Synthesis, biological evaluation and radiochemical labeling of a dansylhydrazone derivative as a potential imaging agent for apoptosis
    • Zeng W, Yao ML, Townsend D, Kabalka G, Wall J, Le Puil M, et al. Synthesis, biological evaluation and radiochemical labeling of a dansylhydrazone derivative as a potential imaging agent for apoptosis. Bioorg Med Chem Lett. 2008; 18: 3573-7.
    • (2008) Bioorg Med Chem Lett , vol.18 , pp. 3573-3577
    • Zeng, W.1    Yao, M.L.2    Townsend, D.3    Kabalka, G.4    Wall, J.5    Le Puil, M.6
  • 122
    • 77955269890 scopus 로고    scopus 로고
    • Design, synthesis, and biological evaluation of 4-(5-dimethylamino-naphthalene-1-sulfon-amido)-3-(4-iodophenyl)butanoic acid as a novel molecular probe for apoptosis imaging
    • Zeng W, Miao W, Le Puil M, Shi G, Biggerstaff J, Kabalka GW, et al. Design, synthesis, and biological evaluation of 4-(5-dimethylamino-naphthalene-1-sulfon-amido)-3-(4-iodophenyl)butanoic acid as a novel molecular probe for apoptosis imaging. Biochem Biophys Res Commun. 2010; 398: 571-5.
    • (2010) Biochem Biophys Res Commun , vol.398 , pp. 571-575
    • Zeng, W.1    Miao, W.2    Le Puil, M.3    Shi, G.4    Biggerstaff, J.5    Kabalka, G.W.6
  • 124
    • 28144443339 scopus 로고    scopus 로고
    • N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies
    • Chu W, Zhang J, Zeng C, Rothfuss J, Tu Z, Chu Y, et al. N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies. J Med Chem. 2005; 48: 7637-47.
    • (2005) J Med Chem , vol.48 , pp. 7637-7647
    • Chu, W.1    Zhang, J.2    Zeng, C.3    Rothfuss, J.4    Tu, Z.5    Chu, Y.6
  • 125
    • 33750976699 scopus 로고    scopus 로고
    • 5-pyrrolidinylsulfonyl isatins as a potential tool for the molecular imaging of caspases in apoptosis
    • Kopka K, Faust A, Keul P, Wagner S, Breyholz HJ, Höltke C, et al. 5-pyrrolidinylsulfonyl isatins as a potential tool for the molecular imaging of caspases in apoptosis. J Med Chem. 2006; 49: 6704-15.
    • (2006) J Med Chem , vol.49 , pp. 6704-6715
    • Kopka, K.1    Faust, A.2    Keul, P.3    Wagner, S.4    Breyholz, H.J.5    Höltke, C.6
  • 126
    • 33747355468 scopus 로고    scopus 로고
    • Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis
    • Zhou D, Chu W, Rothfuss J, Zeng C, Xu J, Jones L, et al. Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis. Bioorg Med Chem Lett. 2006; 16: 5041-6.
    • (2006) Bioorg Med Chem Lett , vol.16 , pp. 5041-5046
    • Zhou, D.1    Chu, W.2    Rothfuss, J.3    Zeng, C.4    Xu, J.5    Jones, L.6
  • 127
    • 0037742189 scopus 로고    scopus 로고
    • 3'-deoxy-3'-[18F]fluorothymidine as a new marker for monitoring tumor response to antiproliferative therapy in vivo with positron emission tomography
    • Barthel H, Cleij MC, Collingridge DR, Hutchinson OC, Osman S, He Q, et al. 3'-deoxy-3'-[18F]fluorothymidine as a new marker for monitoring tumor response to antiproliferative therapy in vivo with positron emission tomography. Cancer Res. 2003; 63: 3791-8.
    • (2003) Cancer Res , vol.63 , pp. 3791-3798
    • Barthel, H.1    Cleij, M.C.2    Collingridge, D.R.3    Hutchinson, O.C.4    Osman, S.5    He, Q.6
  • 128
    • 20144366731 scopus 로고    scopus 로고
    • Early detection of tumor response to chemotherapy by 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography: the effect of cisplatin on a fibrosarcoma tumor model in vivo
    • Leyton J, Latigo JR, Perumal M, Dhaliwal H, He Q, Aboagye EO. Early detection of tumor response to chemotherapy by 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography: the effect of cisplatin on a fibrosarcoma tumor model in vivo. Cancer Res. 2005; 65: 4202-10.
    • (2005) Cancer Res , vol.65 , pp. 4202-4210
    • Leyton, J.1    Latigo, J.R.2    Perumal, M.3    Dhaliwal, H.4    He, Q.5    Aboagye, E.O.6
  • 129
    • 34548173711 scopus 로고    scopus 로고
    • Imaging early changes in proliferation at 1 week post chemotherapy: a pilot study in breast cancer patients with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography
    • Kenny L, Coombes RC, Vigushin DM, Al-Nahhas A, Shousha S, Aboagye EO. Imaging early changes in proliferation at 1 week post chemotherapy: a pilot study in breast cancer patients with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography. Eur J Nucl Med Mol Imaging. 2007; 34: 1339-47.
    • (2007) Eur J Nucl Med Mol Imaging , vol.34 , pp. 1339-1347
    • Kenny, L.1    Coombes, R.C.2    Vigushin, D.M.3    Al-Nahhas, A.4    Shousha, S.5    Aboagye, E.O.6
  • 130
    • 70349481530 scopus 로고    scopus 로고
    • Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide
    • Nguyen QD, Smith G, Glaser M, Perumal M, Arstad E, Aboagye EO. Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide. Proc Natl Acad Sci U S A. 2009; 106: 16375-80.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 16375-16380
    • Nguyen, Q.D.1    Smith, G.2    Glaser, M.3    Perumal, M.4    Arstad, E.5    Aboagye, E.O.6
  • 131
    • 80255129368 scopus 로고    scopus 로고
    • Improved radiosynthesis of the apoptosis marker 18F-ICMT11 including biological evaluation
    • Glaser M, Goggi J, Smith G, Morrison M, Luthra SK, Robins E, et al. Improved radiosynthesis of the apoptosis marker 18F-ICMT11 including biological evaluation. Bioorg Med Chem Lett. 2011; 21: 6945-9.
    • (2011) Bioorg Med Chem Lett , vol.21 , pp. 6945-6949
    • Glaser, M.1    Goggi, J.2    Smith, G.3    Morrison, M.4    Luthra, S.K.5    Robins, E.6
  • 132
    • 84857048259 scopus 로고    scopus 로고
    • Imaging apoptosis with positron emission tomography: 'bench to bedside' development of the caspase-3/7 specific radiotracer [18F]ICMT-11
    • Nguyen QD, Challapalli A, Smith G, Fortt R, Aboagye EO. Imaging apoptosis with positron emission tomography: 'bench to bedside' development of the caspase-3/7 specific radiotracer [18F]ICMT-11. Eur J Cancer. 2012; 48: 432-40.
    • (2012) Eur J Cancer , vol.48 , pp. 432-440
    • Nguyen, Q.D.1    Challapalli, A.2    Smith, G.3    Fortt, R.4    Aboagye, E.O.5
  • 133
    • 84887350708 scopus 로고    scopus 로고
    • 18F-ICMT-11, a caspase-3-specific PET tracer for apoptosis: biodistribution and radiation dosimetry
    • Challapalli A, Kenny LM, Hallett WA, Kozlowski K, Tomasi G, Gudi M, et al. 18F-ICMT-11, a caspase-3-specific PET tracer for apoptosis: biodistribution and radiation dosimetry. J Nucl Med. 2013; 54: 1551-6.
    • (2013) J Nucl Med , vol.54 , pp. 1551-1556
    • Challapalli, A.1    Kenny, L.M.2    Hallett, W.A.3    Kozlowski, K.4    Tomasi, G.5    Gudi, M.6
  • 134
    • 0037879052 scopus 로고    scopus 로고
    • The mitochondrial membrane potential (deltapsi( m)) in apoptosis; an update
    • Ly JD, Grubb DR, Lawen A. The mitochondrial membrane potential (deltapsi( m)) in apoptosis; an update. Apoptosis. 2003; 8: 115-28.
    • (2003) Apoptosis , vol.8 , pp. 115-128
    • Ly, J.D.1    Grubb, D.R.2    Lawen, A.3
  • 135
    • 33749060656 scopus 로고    scopus 로고
    • Characterization of uptake of the new PET imaging compound 18F-fluorobenzyl triphenyl phosphonium in dog myocardium
    • Madar I, Ravert HT, Du Y, Hilton J, Volokh L, Dannals RF, et al. Characterization of uptake of the new PET imaging compound 18F-fluorobenzyl triphenyl phosphonium in dog myocardium. J Nucl Med. 2006; 47: 1359-66.
    • (2006) J Nucl Med , vol.47 , pp. 1359-1366
    • Madar, I.1    Ravert, H.T.2    Du, Y.3    Hilton, J.4    Volokh, L.5    Dannals, R.F.6
  • 136
    • 36749075506 scopus 로고    scopus 로고
    • Characterization of membrane potential-dependent uptake of the novel PET tracer 18F-fluorobenzyl triphenylphosphonium cation
    • Madar I, Ravert H, Nelkin B, Abro M, Pomper M, Dannals R, et al. Characterization of membrane potential-dependent uptake of the novel PET tracer 18F-fluorobenzyl triphenylphosphonium cation. Eur J Nucl Med Mol Imaging. 2007; 34: 2057-65.
    • (2007) Eur J Nucl Med Mol Imaging , vol.34 , pp. 2057-2065
    • Madar, I.1    Ravert, H.2    Nelkin, B.3    Abro, M.4    Pomper, M.5    Dannals, R.6
  • 137
    • 66149109649 scopus 로고    scopus 로고
    • Detection and quantification of the evolution dynamics of apoptosis using the PET voltage sensor 18F-fluorobenzyl triphenyl phosphonium
    • Madar I, Huang Y, Ravert H, Dalrymple SL, Davidson NE, Isaacs JT, et al. Detection and quantification of the evolution dynamics of apoptosis using the PET voltage sensor 18F-fluorobenzyl triphenyl phosphonium. J Nucl Med. 2009; 50: 774-80.
    • (2009) J Nucl Med , vol.50 , pp. 774-780
    • Madar, I.1    Huang, Y.2    Ravert, H.3    Dalrymple, S.L.4    Davidson, N.E.5    Isaacs, J.T.6
  • 138
    • 77957950297 scopus 로고    scopus 로고
    • Imaging the life and death of tumors in living subjects: Preclinical PET imaging of proliferation and apoptosis
    • Nguyen QD, Aboagye EO. Imaging the life and death of tumors in living subjects: Preclinical PET imaging of proliferation and apoptosis. Integr Biol. 2010; 2: 483-95.
    • (2010) Integr Biol , vol.2 , pp. 483-495
    • Nguyen, Q.D.1    Aboagye, E.O.2
  • 139
    • 34447498813 scopus 로고    scopus 로고
    • Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer
    • Rodina A, Vilenchik M, Moulick K, Aguirre J, Kim J, Chiang A, et al. Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. Nat Chem Biol. 2007;3: 498-507.
    • (2007) Nat Chem Biol , vol.3 , pp. 498-507
    • Rodina, A.1    Vilenchik, M.2    Moulick, K.3    Aguirre, J.4    Kim, J.5    Chiang, A.6
  • 140
    • 58849160500 scopus 로고    scopus 로고
    • Heat shock protein 90 as a drug target: some like it hot
    • Banerji U. Heat shock protein 90 as a drug target: some like it hot. Clin Cancer Res. 2009; 15: 9-14.
    • (2009) Clin Cancer Res , vol.15 , pp. 9-14
    • Banerji, U.1
  • 142
    • 34247324472 scopus 로고    scopus 로고
    • Optical molecular imaging agents for cancer diagnostics and therapeutics
    • Kumar S, Richards-Kortum R. Optical molecular imaging agents for cancer diagnostics and therapeutics. Nanomedicine. 2006; 1: 23-30.
    • (2006) Nanomedicine , vol.1 , pp. 23-30
    • Kumar, S.1    Richards-Kortum, R.2
  • 143
    • 78650292049 scopus 로고    scopus 로고
    • The insatiable quest for near-infrared fluorescent probes for molecular imaging
    • Achilefu S. The insatiable quest for near-infrared fluorescent probes for molecular imaging. Angew Chem Int Ed. 2010; 49: 9816-8.
    • (2010) Angew Chem Int Ed , vol.49 , pp. 9816-9818
    • Achilefu, S.1
  • 144
    • 70449719361 scopus 로고    scopus 로고
    • Identification of human pancreatic cancer stem cells
    • Li C, Lee CJ, Simeone DM. Identification of human pancreatic cancer stem cells. Methods Mol Biol. 2009; 568: 161-73.
    • (2009) Methods Mol Biol , vol.568 , pp. 161-173
    • Li, C.1    Lee, C.J.2    Simeone, D.M.3
  • 145
    • 65149086780 scopus 로고    scopus 로고
    • Biosensing and imaging based on bioluminescence resonance energy transfer
    • Xia Z, Rao J. Biosensing and imaging based on bioluminescence resonance energy transfer. Curr. Opin Biotechnol. 2009; 20: 37-44.
    • (2009) Curr. Opin Biotechnol , vol.20 , pp. 37-44
    • Xia, Z.1    Rao, J.2
  • 148
    • 74849090694 scopus 로고    scopus 로고
    • Optical imaging of mammary and prostate tumors in living animals using a synthetic near infrared zinc(II)-dipicolylamine probe for anionic cell surfaces
    • Smith BA, Akers WJ, Leevy WM, Lampkins AJ, Xiao S, Wolter W, et al. Optical imaging of mammary and prostate tumors in living animals using a synthetic near infrared zinc(II)-dipicolylamine probe for anionic cell surfaces. J Am Chem Soc. 2010; 132: 67-9.
    • (2010) J Am Chem Soc , vol.132 , pp. 67-69
    • Smith, B.A.1    Akers, W.J.2    Leevy, W.M.3    Lampkins, A.J.4    Xiao, S.5    Wolter, W.6
  • 149
    • 79953807412 scopus 로고    scopus 로고
    • In vivo optical imaging of acute cell death using a near-infrared fluorescent zinc-dipicolylamine probe
    • Smith BA, Gammon ST, Xiao S, Wang W, Chapman S, McDermott R, et al. In vivo optical imaging of acute cell death using a near-infrared fluorescent zinc-dipicolylamine probe. Mol Pharm. 2011; 8: 583-90.
    • (2011) Mol Pharm , vol.8 , pp. 583-590
    • Smith, B.A.1    Gammon, S.T.2    Xiao, S.3    Wang, W.4    Chapman, S.5    McDermott, R.6
  • 150
    • 41649110649 scopus 로고    scopus 로고
    • Imaging in the era of molecular oncology
    • Weissleder R, Pittet MJ. Imaging in the era of molecular oncology. Nature. 2008; 452: 580-9.
    • (2008) Nature , vol.452 , pp. 580-589
    • Weissleder, R.1    Pittet, M.J.2
  • 151
    • 79951590463 scopus 로고    scopus 로고
    • Target-cancer-cell-specific activatable fluorescence imaging probes: rational design and in vivo applications
    • Kobayashi H, Choyke PL. Target-cancer-cell-specific activatable fluorescence imaging probes: rational design and in vivo applications. Acc Chem Res. 2011; 44: 83-90.
    • (2011) Acc Chem Res , vol.44 , pp. 83-90
    • Kobayashi, H.1    Choyke, P.L.2
  • 153
    • 84862533366 scopus 로고    scopus 로고
    • Design of "smart" probes for optical imaging of apoptosis
    • Huang X, Lee S, Chen X. Design of "smart" probes for optical imaging of apoptosis. Am J Nucl Med Mol Imaging. 2007; 1: 3-17.
    • (2007) Am J Nucl Med Mol Imaging , vol.1 , pp. 3-17
    • Huang, X.1    Lee, S.2    Chen, X.3
  • 154
    • 23944469298 scopus 로고    scopus 로고
    • Synthesis and characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis
    • Bullok K, Piwnica-Worms D. Synthesis and characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis. J Med Chem. 2005; 48: 5404-7.
    • (2005) J Med Chem , vol.48 , pp. 5404-5407
    • Bullok, K.1    Piwnica-Worms, D.2
  • 155
    • 34047219123 scopus 로고    scopus 로고
    • Biochemical and in vivo characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis
    • Bullok KE, Maxwell D, Kesarwala AH, Gammon S, Prior JL, Snow M, et al. Biochemical and in vivo characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis. Biochemistry. 2007; 46: 4055-65.
    • (2007) Biochemistry , vol.46 , pp. 4055-4065
    • Bullok, K.E.1    Maxwell, D.2    Kesarwala, A.H.3    Gammon, S.4    Prior, J.L.5    Snow, M.6
  • 156
    • 67249095097 scopus 로고    scopus 로고
    • Single-cell imaging of retinal ganglion cell apoptosis with a cell-penetrating, activatable peptide probe in an in vivo glaucoma model
    • Barnett EM, Zhang X, Maxwell D, Chang Q, Piwnica-Worms D. Single-cell imaging of retinal ganglion cell apoptosis with a cell-penetrating, activatable peptide probe in an in vivo glaucoma model. Proc Natl Acad Sci U S A. 2009; 106: 9391-6.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9391-9396
    • Barnett, E.M.1    Zhang, X.2    Maxwell, D.3    Chang, Q.4    Piwnica-Worms, D.5
  • 157
    • 65249177729 scopus 로고    scopus 로고
    • An improved cell-penetrating, caspase-activatable, near-infrared fluorescent peptide for apoptosis imaging
    • Maxwell D, Chang Q, Zhang X, Barnett EM, Piwnica-Worms D. An improved cell-penetrating, caspase-activatable, near-infrared fluorescent peptide for apoptosis imaging. Bioconjug Chem. 2009; 20: 702-9.
    • (2009) Bioconjug Chem , vol.20 , pp. 702-709
    • Maxwell, D.1    Chang, Q.2    Zhang, X.3    Barnett, E.M.4    Piwnica-Worms, D.5
  • 158
    • 79951701642 scopus 로고    scopus 로고
    • Real time, high resolution video imaging of apoptosis in single cells with a polymeric nanoprobe
    • Lee S, Choi KY, Chung H, Ryu JH, Lee A, Koo H, et al. Real time, high resolution video imaging of apoptosis in single cells with a polymeric nanoprobe. Bioconjug Chem. 2011; 22: 125-31.
    • (2011) Bioconjug Chem , vol.22 , pp. 125-131
    • Lee, S.1    Choi, K.Y.2    Chung, H.3    Ryu, J.H.4    Lee, A.5    Koo, H.6
  • 159
    • 84866740090 scopus 로고    scopus 로고
    • Real-time monitoring of caspase cascade activation in living cells
    • Zhu L, Huang X, Choi KY, Ma Y, Zhang F, Liu G, et al. Real-time monitoring of caspase cascade activation in living cells. J Control Release. 2012; 163: 55-62.
    • (2012) J Control Release , vol.163 , pp. 55-62
    • Zhu, L.1    Huang, X.2    Choi, K.Y.3    Ma, Y.4    Zhang, F.5    Liu, G.6
  • 160
    • 84863044802 scopus 로고    scopus 로고
    • Multiplex imaging of an intracellular proteolytic cascade by using a broad-spectrum nanoquencher
    • Huang X, Swierczewska M, Choi KY, Zhu L, Bhirde A, Kim K, et al. Multiplex imaging of an intracellular proteolytic cascade by using a broad-spectrum nanoquencher. Angew Chem Int Ed. 2012; 51: 1625-30.
    • (2012) Angew Chem Int Ed , vol.51 , pp. 1625-1630
    • Huang, X.1    Swierczewska, M.2    Choi, K.Y.3    Zhu, L.4    Bhirde, A.5    Kim, K.6
  • 161
    • 3042541034 scopus 로고    scopus 로고
    • Quantitative comparison of the sensitivity of detection of fluorescent and bioluminescent reporters in animal models
    • Troy T, Jekic-McMullen D, Sambucetti L, Rice B. Quantitative comparison of the sensitivity of detection of fluorescent and bioluminescent reporters in animal models. Mol Imaging. 2004; 3: 9-23.
    • (2004) Mol Imaging , vol.3 , pp. 9-23
    • Troy, T.1    Jekic-McMullen, D.2    Sambucetti, L.3    Rice, B.4
  • 162
    • 2442562277 scopus 로고    scopus 로고
    • A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging
    • Ponomarev V, Doubrovin M, Serganova I, Vider J, Shavrin A, Beresten T, et al. A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging. Eur J Nucl Med Mol Imaging. 2004; 31: 740-51.
    • (2004) Eur J Nucl Med Mol Imaging , vol.31 , pp. 740-751
    • Ponomarev, V.1    Doubrovin, M.2    Serganova, I.3    Vider, J.4    Shavrin, A.5    Beresten, T.6
  • 163
    • 35048844611 scopus 로고    scopus 로고
    • Cyclic luciferase for real-time sensing of caspase-3 activities in living mammals
    • Kanno A, Yamanaka Y, Hirano H, Umezawa Y, Ozawa T. Cyclic luciferase for real-time sensing of caspase-3 activities in living mammals. Angew Chem Int Ed. 2007; 46: 7595-9.
    • (2007) Angew Chem Int Ed , vol.46 , pp. 7595-7599
    • Kanno, A.1    Yamanaka, Y.2    Hirano, H.3    Umezawa, Y.4    Ozawa, T.5
  • 165
    • 84882947458 scopus 로고    scopus 로고
    • Longitudinal bioluminescence imaging of the dynamics of Doxorubicin induced apoptosis
    • Niu G, Zhu L, Ho DN, Zhang F, Quan Q, Hida N, et al. Longitudinal bioluminescence imaging of the dynamics of Doxorubicin induced apoptosis. Theranostics. 2013; 3: 190-200.
    • (2013) Theranostics , vol.3 , pp. 190-200
    • Niu, G.1    Zhu, L.2    Ho, D.N.3    Zhang, F.4    Quan, Q.5    Hida, N.6
  • 166
    • 0037039437 scopus 로고    scopus 로고
    • Optical imaging of Renilla luciferase reporter gene expression in living mice
    • Bhaumik S, Gambhir SS. Optical imaging of Renilla luciferase reporter gene expression in living mice. Proc Natl Acad Sci U S A. 2002; 99: 377-82.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 377-382
    • Bhaumik, S.1    Gambhir, S.S.2
  • 167
    • 0242490131 scopus 로고    scopus 로고
    • Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo
    • Shah K, Tang Y, Breakefield X, Weissleder R. Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo. Oncogene. 2003; 22:6865-72.
    • (2003) Oncogene. , vol.22 , pp. 6865-6872
    • Shah, K.1    Tang, Y.2    Breakefield, X.3    Weissleder, R.4
  • 168
    • 0034724192 scopus 로고    scopus 로고
    • Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)
    • Angers S, Salahpour A, Joly E, Hilairet S, Chelsky D, Dennis M, et al. Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET). Proc Natl Acad Sci U S A. 2000; 97:3684-9.
    • (2000) Proc Natl Acad Sci U S A. , vol.97 , pp. 3684-3689
    • Angers, S.1    Salahpour, A.2    Joly, E.3    Hilairet, S.4    Chelsky, D.5    Dennis, M.6
  • 169
    • 48249097524 scopus 로고    scopus 로고
    • The technology of MRI--the next 10 years?
    • Blamire AM. The technology of MRI--the next 10 years? Br J Radiol. 2008; 81:601-17.
    • (2008) Br J Radiol , vol.81 , pp. 601-617
    • Blamire, A.M.1
  • 170
    • 0033363494 scopus 로고    scopus 로고
    • Gadolinium(III) chelates as MRI contrast agents: structure, dynamics, and applications
    • Caravan P, Ellison JJ, McMurry TJ, Lauffer RB. Gadolinium(III) chelates as MRI contrast agents: structure, dynamics, and applications. Chem Rev. 1999; 99: 2293-352.
    • (1999) Chem Rev , vol.99 , pp. 2293-2352
    • Caravan, P.1    Ellison, J.J.2    McMurry, T.J.3    Lauffer, R.B.4
  • 171
    • 84858690211 scopus 로고    scopus 로고
    • Designed synthesis of uniformly sized iron oxide nanoparticles for efficient magnetic resonance imaging contrast agents
    • Lee N, Hyeon T. Designed synthesis of uniformly sized iron oxide nanoparticles for efficient magnetic resonance imaging contrast agents. Chem Soc Rev. 2012; 41: 2575-89.
    • (2012) Chem Soc Rev , vol.41 , pp. 2575-2589
    • Lee, N.1    Hyeon, T.2
  • 172
    • 84871659077 scopus 로고    scopus 로고
    • Gadolinium-based contrast agents for magnetic resonance cancer imaging
    • Zhou Z, Lu ZR. Gadolinium-based contrast agents for magnetic resonance cancer imaging. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2013; 5:1-18.
    • (2013) Wiley Interdiscip Rev Nanomed Nanobiotechnol. , vol.5 , pp. 1-18
    • Zhou, Z.1    Lu, Z.R.2
  • 173
    • 80053461748 scopus 로고    scopus 로고
    • Surface-engineered magnetic nanoparticle platforms for cancer imaging and therapy
    • Xie J, Liu G, Eden HS, Ai H, Chen X. Surface-engineered magnetic nanoparticle platforms for cancer imaging and therapy. Acc Chem Res. 2011; 44: 883-92.
    • (2011) Acc Chem Res , vol.44 , pp. 883-892
    • Xie, J.1    Liu, G.2    Eden, H.S.3    Ai, H.4    Chen, X.5
  • 174
    • 84887357438 scopus 로고    scopus 로고
    • Surface modification: how nanoparticles assemble to molecular imaging probes
    • Tan H, Yu L, Gao F, Liao W, Wang W, Zeng W. Surface modification: how nanoparticles assemble to molecular imaging probes. J Nanopart Res. 2013; 15:2100-15.
    • (2013) J Nanopart Res. , vol.15 , pp. 2100-2115
    • Tan, H.1    Yu, L.2    Gao, F.3    Liao, W.4    Wang, W.5    Zeng, W.6
  • 175
    • 33744516119 scopus 로고    scopus 로고
    • Strategies for increasing the sensitivity of gadolinium based MRI contrast agents
    • Caravan P. Strategies for increasing the sensitivity of gadolinium based MRI contrast agents. Chem Soc Rev. 2006; 35: 512-23.
    • (2006) Chem Soc Rev , vol.35 , pp. 512-523
    • Caravan, P.1
  • 176
    • 33746276976 scopus 로고    scopus 로고
    • Assessment of cardiovascular apoptosis in the isolated rat heart by magnetic resonance molecular imaging
    • Hiller KH, Waller C, Nahrendorf M, Bauer WR, Jakob PM. Assessment of cardiovascular apoptosis in the isolated rat heart by magnetic resonance molecular imaging. Mol Imaging. 2006;5: 115-21.
    • (2006) Mol Imaging , vol.5 , pp. 115-121
    • Hiller, K.H.1    Waller, C.2    Nahrendorf, M.3    Bauer, W.R.4    Jakob, P.M.5
  • 178
    • 77958197104 scopus 로고    scopus 로고
    • Annexin A5-functionalized bimodal nanoparticles for MRI and fluorescence imaging of atherosclerotic plaques
    • van Tilborg GA, Vucic E, Strijkers GJ, Cormode DP, Mani V, Skajaa T, et al. Annexin A5-functionalized bimodal nanoparticles for MRI and fluorescence imaging of atherosclerotic plaques. Bioconjug Chem. 2011; 21: 1794-803.
    • (2011) Bioconjug Chem , vol.21 , pp. 1794-1803
    • van Tilborg, G.A.1    Vucic, E.2    Strijkers, G.J.3    Cormode, D.P.4    Mani, V.5    Skajaa, T.6
  • 179
    • 40949121437 scopus 로고    scopus 로고
    • Detection of cell death in tumors by using MR imaging and a gadolinium-based targeted contrast agent
    • Krishnan AS, Neves AA, de Backer MM, Hu DE, Davletov B, Kettunen MI, et al. Detection of cell death in tumors by using MR imaging and a gadolinium-based targeted contrast agent. Radiology. 2008; 246: 854-62.
    • (2008) Radiology , vol.246 , pp. 854-862
    • Krishnan, A.S.1    Neves, A.A.2    de Backer, M.M.3    Hu, D.E.4    Davletov, B.5    Kettunen, M.I.6
  • 180
    • 71949090316 scopus 로고    scopus 로고
    • Peptidic targeting of phosphatidylserine for the MRI detection of apoptosis in atherosclerotic plaques
    • Burtea C, Laurent S, Lancelot E, Ballet S, Murariu O, Rousseaux O, et al. Peptidic targeting of phosphatidylserine for the MRI detection of apoptosis in atherosclerotic plaques. Mol Pharm. 2009; 6: 1903-19.
    • (2009) Mol Pharm , vol.6 , pp. 1903-1919
    • Burtea, C.1    Laurent, S.2    Lancelot, E.3    Ballet, S.4    Murariu, O.5    Rousseaux, O.6
  • 181
    • 77952795526 scopus 로고    scopus 로고
    • Design, synthesis and biological application of chemical probes for bio-imaging
    • Kikuchi K. Design, synthesis and biological application of chemical probes for bio-imaging. Chem Soc Rev. 2010; 39: 2048-53.
    • (2010) Chem Soc Rev , vol.39 , pp. 2048-2053
    • Kikuchi, K.1
  • 183
    • 70349976207 scopus 로고    scopus 로고
    • Dual-function probe to detect protease activity for fluorescence measurement and 19F MRI
    • Mizukami S, Takikawa R, Sugihara F, Shirakawa M, Kikuchi K. Dual-function probe to detect protease activity for fluorescence measurement and 19F MRI. Angew Chem Int Ed. 2009; 48: 3641-3.
    • (2009) Angew Chem Int Ed , vol.48 , pp. 3641-3643
    • Mizukami, S.1    Takikawa, R.2    Sugihara, F.3    Shirakawa, M.4    Kikuchi, K.5
  • 184
    • 33750434288 scopus 로고    scopus 로고
    • A PARACEST MRI contrast agent to detect enzyme activity
    • Yoo B, Pagel MD. A PARACEST MRI contrast agent to detect enzyme activity. J Am Chem Soc. 2006; 128: 14032-3.
    • (2006) J Am Chem Soc , vol.128 , pp. 14032-14033
    • Yoo, B.1    Pagel, M.D.2
  • 185
    • 84869166858 scopus 로고    scopus 로고
    • Magnetic nanoparticles: design and characterization, toxicity and biocompatibility, pharmaceutical and biomedical applications
    • Reddy LH, Arias JL, Nicolas J, Couvreur P. Magnetic nanoparticles: design and characterization, toxicity and biocompatibility, pharmaceutical and biomedical applications. Chem Rev. 2012; 112: 5818-78.
    • (2012) Chem Rev , vol.112 , pp. 5818-5878
    • Reddy, L.H.1    Arias, J.L.2    Nicolas, J.3    Couvreur, P.4
  • 186
    • 80054727258 scopus 로고    scopus 로고
    • Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy
    • Tassa C, Shaw SY, Weissleder R. Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy. Acc Chem Res. 2011; 44: 842-52.
    • (2011) Acc Chem Res , vol.44 , pp. 842-852
    • Tassa, C.1    Shaw, S.Y.2    Weissleder, R.3
  • 190
    • 0035173736 scopus 로고    scopus 로고
    • Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent
    • Zhao M, Beauregard DA, Loizou L, Davletov B, Brindle KM. Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent. Nat Med. 2001; 7: 1241-4.
    • (2001) Nat Med , vol.7 , pp. 1241-1244
    • Zhao, M.1    Beauregard, D.A.2    Loizou, L.3    Davletov, B.4    Brindle, K.M.5
  • 191
    • 78349272807 scopus 로고    scopus 로고
    • Iron oxide particles covered with hexapeptides targeted at phosphatidylserine as MR biomarkers of tumor cell death
    • Radermacher KA, Boutry S, Laurent S, Elst LV, Mahieu I, Bouzin C, et al. Iron oxide particles covered with hexapeptides targeted at phosphatidylserine as MR biomarkers of tumor cell death. Contr Media Mol Imaging. 2010; 5: 258-67.
    • (2010) Contr Media Mol Imaging , vol.5 , pp. 258-267
    • Radermacher, K.A.1    Boutry, S.2    Laurent, S.3    Elst, L.V.4    Mahieu, I.5    Bouzin, C.6
  • 192
    • 84858864636 scopus 로고    scopus 로고
    • Multimodal assessment of early tumor response to chemotherapy: comparison between diffusion-weighted MRI,1H-MR spectroscopy of choline and USPIO particles targeted at cell death
    • Radermacher KA, Magat J, Bouzin C, Dresselaers T, Himmelreich U, Boutry S, et al. Multimodal assessment of early tumor response to chemotherapy: comparison between diffusion-weighted MRI,1H-MR spectroscopy of choline and USPIO particles targeted at cell death. NMR Biomed. 2011; 25: 514-22.
    • (2011) NMR Biomed , vol.25 , pp. 514-522
    • Radermacher, K.A.1    Magat, J.2    Bouzin, C.3    Dresselaers, T.4    Himmelreich, U.5    Boutry, S.6
  • 193
    • 84861526365 scopus 로고    scopus 로고
    • Development of a magnetic resonance imaging protocol for the characterization of atherosclerotic plaque by using vascular cell adhesion molecule-1 and apoptosis-targeted ultrasmall superparamagnetic iron oxide derivatives
    • Burtea C, Ballet S, Laurent S, Rousseaux O, Dencausse A, Gonzalez W, et al. Development of a magnetic resonance imaging protocol for the characterization of atherosclerotic plaque by using vascular cell adhesion molecule-1 and apoptosis-targeted ultrasmall superparamagnetic iron oxide derivatives. Arterioscler Thromb Vasc Biol. 2012; 32: e36-348.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. e36-348
    • Burtea, C.1    Ballet, S.2    Laurent, S.3    Rousseaux, O.4    Dencausse, A.5    Gonzalez, W.6
  • 195
    • 77952537647 scopus 로고    scopus 로고
    • Multimodality imaging probes: design and challenges
    • Louie A. Multimodality imaging probes: design and challenges. Chem Rev. 2010; 110: 3146-95.
    • (2010) Chem Rev , vol.110 , pp. 3146-3195
    • Louie, A.1
  • 196
    • 84875206491 scopus 로고    scopus 로고
    • Functionalizing nanoparticles with biological molecules: developing chemistries that facilitate nanotechnology
    • Sapsford KE, Algar WR, Berti L, Gemmill KB, Casey BJ, Oh E, et al. Functionalizing nanoparticles with biological molecules: developing chemistries that facilitate nanotechnology. Chem Rev. 2013; 113: 1904-2074.
    • (2013) Chem Rev , vol.113 , pp. 1904-2074
    • Sapsford, K.E.1    Algar, W.R.2    Berti, L.3    Gemmill, K.B.4    Casey, B.J.5    Oh, E.6
  • 197
    • 84893523047 scopus 로고    scopus 로고
    • Radiolabeled nanoparticles for multimodality tumor imaging
    • Xing Y, Zhao J, Conti PS, Chen K. Radiolabeled nanoparticles for multimodality tumor imaging. Theranostics. 2014; 4: 290-306.
    • (2014) Theranostics , vol.4 , pp. 290-306
    • Xing, Y.1    Zhao, J.2    Conti, P.S.3    Chen, K.4
  • 198
    • 84863338346 scopus 로고    scopus 로고
    • Multifunctional nanoparticles for multimodal imaging and theragnosis
    • Lee DE, Koo H, Sun IC, Ryu JH, Kim K, Kwon IC. Multifunctional nanoparticles for multimodal imaging and theragnosis. Chem Soc Rev. 2012; 41: 2656-72.
    • (2012) Chem Soc Rev , vol.41 , pp. 2656-2672
    • Lee, D.E.1    Koo, H.2    Sun, I.C.3    Ryu, J.H.4    Kim, K.5    Kwon, I.C.6
  • 201
    • 33746717495 scopus 로고    scopus 로고
    • Annexin A5-conjugated quantum dots with a paramagnetic lipidic coating for the multimodal detection of apoptotic cells
    • van Tilborg GA, Mulder WJ, Chin PT, Storm G, Reutelingsperger CP, Nicolay K, et al. Annexin A5-conjugated quantum dots with a paramagnetic lipidic coating for the multimodal detection of apoptotic cells. Bioconjug Chem. 2006; 17: 865-8.
    • (2006) Bioconjug Chem , vol.17 , pp. 865-868
    • van Tilborg, G.A.1    Mulder, W.J.2    Chin, P.T.3    Storm, G.4    Reutelingsperger, C.P.5    Nicolay, K.6
  • 202
    • 77958197104 scopus 로고    scopus 로고
    • Annexin A5-functionalized bimodal nanoparticles for MRI and fluorescence imaging of atherosclerotic plaques
    • van Tilborg GA, Vucic E, Strijkers GJ, Cormode DP, Mani V, Skajaa T, et al. Annexin A5-functionalized bimodal nanoparticles for MRI and fluorescence imaging of atherosclerotic plaques. Bioconjug Chem. 2010; 21: 1794-803.
    • (2010) Bioconjug Chem , vol.21 , pp. 1794-1803
    • van Tilborg, G.A.1    Vucic, E.2    Strijkers, G.J.3    Cormode, D.P.4    Mani, V.5    Skajaa, T.6
  • 203
    • 79958136891 scopus 로고    scopus 로고
    • Annexin A5-conjugated polymeric micelles for dual SPECT and optical detection of apoptosis
    • Zhang R, Lu W, Wen X, Huang M, Zhou M, Liang D, et al. Annexin A5-conjugated polymeric micelles for dual SPECT and optical detection of apoptosis. J Nucl Med. 2011; 52: 958-64.
    • (2011) J Nucl Med , vol.52 , pp. 958-964
    • Zhang, R.1    Lu, W.2    Wen, X.3    Huang, M.4    Zhou, M.5    Liang, D.6
  • 204
    • 84879223713 scopus 로고    scopus 로고
    • Annexin A5-functionalized nanoparticle for multimodal imaging of cell death
    • Zhang R, Huang M, Zhou M, Wen X, Huang Q, Li C. Annexin A5-functionalized nanoparticle for multimodal imaging of cell death. Mol Imaging. 2013; 12: 182-90.
    • (2013) Mol Imaging , vol.12 , pp. 182-190
    • Zhang, R.1    Huang, M.2    Zhou, M.3    Wen, X.4    Huang, Q.5    Li, C.6
  • 205
    • 84898647966 scopus 로고    scopus 로고
    • Phosphatidylserine-targeted bimodal liposomal nanoparticles for in vivo imaging of breast cancer in mice
    • Zhang L, Zhou H, Belzile O, Thorpe P, Zhao D. Phosphatidylserine-targeted bimodal liposomal nanoparticles for in vivo imaging of breast cancer in mice. J Control Release. 2014; 183: 114-23.
    • (2014) J Control Release , vol.183 , pp. 114-123
    • Zhang, L.1    Zhou, H.2    Belzile, O.3    Thorpe, P.4    Zhao, D.5
  • 206
    • 73349086909 scopus 로고    scopus 로고
    • Complementary optical and nuclear imaging of caspase-3 activity using combined activatable and radio-labeled multimodality molecular probe
    • Lee H, Akers WJ, Cheney PP, Edwards WB, Liang K, Culver JP, et al. Complementary optical and nuclear imaging of caspase-3 activity using combined activatable and radio-labeled multimodality molecular probe. J Biomed Opt. 2009; 14: 040507.
    • (2009) J Biomed Opt , vol.14 , pp. 040507
    • Lee, H.1    Akers, W.J.2    Cheney, P.P.3    Edwards, W.B.4    Liang, K.5    Culver, J.P.6
  • 207
    • 46749092088 scopus 로고    scopus 로고
    • In vivo detection of apoptosis
    • Blankenberg, FG. In vivo detection of apoptosis. J Nucl Med. 2008; 49(Suppl 2):S81-S95.
    • (2008) J Nucl Med , vol.49 , pp. S81-S95
    • Blankenberg, F.G.1
  • 208
    • 77953930252 scopus 로고    scopus 로고
    • Small-molecule biomarkers for clinical PET imaging of apoptosis
    • Reshef A, Shirvan A, Akselrod-Ballin A, Wall A, and Ziv I. Small-molecule biomarkers for clinical PET imaging of apoptosis. J Nucl Med. 2010; 51: 837-40.
    • (2010) J Nucl Med , vol.51 , pp. 837-840
    • Reshef, A.1    Shirvan, A.2    Akselrod-Ballin, A.3    Wall, A.4    Ziv, I.5
  • 209
    • 79851482376 scopus 로고    scopus 로고
    • Apoptosis imaging: beyond annexin V
    • Niu G, Chen X. Apoptosis imaging: beyond annexin V. J Nucl Med. 2010; 51:1659-62.
    • (2010) J Nucl Med. , vol.51 , pp. 1659-1662
    • Niu, G.1    Chen, X.2
  • 211
  • 212
    • 77955645834 scopus 로고    scopus 로고
    • Design and development of molecular imaging probes
    • Chen K, Chen X. Design and development of molecular imaging probes. Curr Top Med Chem. 2010; 10: 1227-36.
    • (2010) Curr Top Med Chem , vol.10 , pp. 1227-1236
    • Chen, K.1    Chen, X.2
  • 213
    • 84930625051 scopus 로고    scopus 로고
    • Use of eINDs for evaluation of multiple related PET amyloid plaque imaging agents
    • Skovronsky D. Use of eINDs for evaluation of multiple related PET amyloid plaque imaging agents. J Nucl Med. 2008; 49: 4-8.
    • (2008) J Nucl Med , vol.49 , pp. 4-8
    • Skovronsky, D.1
  • 214
    • 84906872153 scopus 로고    scopus 로고
    • Intraoperative imaging-guided cancer surgery: from current fluorescence molecular imaging methods to future multi-modality imaging technology
    • Chi C, Du Y, Ye J, Kou D, Qiu J, Wang J, et al. Intraoperative imaging-guided cancer surgery: from current fluorescence molecular imaging methods to future multi-modality imaging technology. Theranostics. 2014; 4: 1072-84.
    • (2014) Theranostics , vol.4 , pp. 1072-1084
    • Chi, C.1    Du, Y.2    Ye, J.3    Kou, D.4    Qiu, J.5    Wang, J.6
  • 215
    • 78651275357 scopus 로고    scopus 로고
    • Apoptosis imaging with PET-18F-ML-10 for early assessment of response of brain metastasis to radiotherapy
    • Shirvan A. Apoptosis imaging with PET-18F-ML-10 for early assessment of response of brain metastasis to radiotherapy. J Nucl Med. 2009; 50(Suppl 1):S118.
    • (2009) J Nucl Med , vol.50 , pp. S118
    • Shirvan, A.1
  • 216
    • 77958089628 scopus 로고    scopus 로고
    • Detection of apoptosis: a review of conventional and novel techniques
    • Martinez MM, Reif RD, Pappas D. Detection of apoptosis: a review of conventional and novel techniques. Anal Methods. 2010; 2: 996-1004.
    • (2010) Anal Methods , vol.2 , pp. 996-1004
    • Martinez, M.M.1    Reif, R.D.2    Pappas, D.3
  • 217
    • 80054745992 scopus 로고    scopus 로고
    • Molecular imaging with theranostic nanoparticles
    • Jokerst JV, Gambhir SS. Molecular imaging with theranostic nanoparticles. Acc Chem Res. 2011; 44: 1050-60.
    • (2011) Acc Chem Res , vol.44 , pp. 1050-1060
    • Jokerst, J.V.1    Gambhir, S.S.2
  • 220
    • 84862864780 scopus 로고    scopus 로고
    • Magnetic nanoparticle-based theranostics
    • Xie J, Jon S. Magnetic nanoparticle-based theranostics. Theranostics. 2012; 2:122-4.
    • (2012) Theranostics. , vol.2 , pp. 122-124
    • Xie, J.1    Jon, S.2
  • 221
    • 84902529384 scopus 로고    scopus 로고
    • Nanotheranostics - application and further development of nanomedicine strategies for advanced theranostics
    • Muthu MS, Leong DT, Mei L, Feng SS. Nanotheranostics - application and further development of nanomedicine strategies for advanced theranostics. Theranostics. 2014; 4: 660-77.
    • (2014) Theranostics , vol.4 , pp. 660-677
    • Muthu, M.S.1    Leong, D.T.2    Mei, L.3    Feng, S.S.4
  • 222
    • 84864563925 scopus 로고    scopus 로고
    • Protease activity: meeting its theranostic potential
    • Lee S, Kim K. Protease activity: meeting its theranostic potential. Theranostics. 2012; 2: 125-6.
    • (2012) Theranostics , vol.2 , pp. 125-126
    • Lee, S.1    Kim, K.2
  • 223
    • 84893232913 scopus 로고    scopus 로고
    • Near-infrared light-mediated photoactivation of a platinum antitumor prodrug and simultaneous cellular apoptosis imaging by upconversion-luminescent nanoparticles
    • Min Y, Li J, Liu F, Yeow EK, Xing B. Near-infrared light-mediated photoactivation of a platinum antitumor prodrug and simultaneous cellular apoptosis imaging by upconversion-luminescent nanoparticles. Angew Chem Int Ed. 2014; 53: 1012-6.
    • (2014) Angew Chem Int Ed , vol.53 , pp. 1012-1016
    • Min, Y.1    Li, J.2    Liu, F.3    Yeow, E.K.4    Xing, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.