Design, synthesis, and biological evaluation of 4-(5-dimethylamino-naphthalene-1-sulfon-amido)-3-(4-iodophenyl)butanoic acid as a novel molecular probe for apoptosis imaging

Biochemical and Biophysical Research Communications

Volumn 398, Issue 3, 2010, Pages 571-575

  Zeng, Wenbin ^a,b   Miao, Weimin ^b   Le Puil, Michael ^c   Shi, Guangqing ^a   Biggerstaff, John ^c   Kabalka, George W ^b   Townsend, David ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b UNIVERSITY OF TENNESSEE GRADUATE SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TENNESSEE   (United States)

Author keywords

Annexin V; Apoptosis; Molecular imaging; Molecular probe

Indexed keywords

4 (5 DIMETHYLAMINO NAPHTHALENE 1 SULFONAMIDO) 3 (4 IODOPHENYL)BUTANOIC ACID; 4 (5 DIMETHYLAMINO NAPHTHALENE 1 SULFONAMIDO) 3 (4 IODOPHENYL)BUTANOIC ACID I 123; 4 (5 DIMETHYLAMINO NAPHTHALENE 1 SULFONAMIDO) 3 (4 IODOPHENYL)BUTANOIC ACID I 124; 4 (5 DIMETHYLAMINO NAPHTHALENE 1 SULFONAMIDO) 3 (4 IODOPHENYL)BUTANOIC ACID I 131; AMINE; BUTYRIC ACID DERIVATIVE; IODINE DERIVATIVE; NAPHTHALENE DERIVATIVE; RADIOISOTOPE; SULFONAMIDE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER STAGING; DRUG DESIGN; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; ISOTOPE LABELING; MOLECULAR PROBE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTUM YIELD; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

APOPTOSIS; CELL LINE, TUMOR; DANSYL COMPOUNDS; FLUORESCENT DYES; HUMANS; NEOPLASMS; PHENYLPROPIONATES; POSITRON-EMISSION TOMOGRAPHY;

EID: 77955269890     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.06.120     Document Type: Article

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