Small-molecule biomarkers for clinical PET imaging of apoptosis

Journal of Nuclear Medicine

Volumn 51, Issue 6, 2010, Pages 837-840

  Reshef, Ayelet ^a   Shirvan, Anat ^a   Akselrod Ballin, Ayelet ^b   Wall, Anders ^c   Ziv, Ilan ^a  

^a Aposense Ltd   (Israel)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c Uppsala Imanet   (Sweden)

Author keywords

Apoptosis; Molecular imaging; PET; Small molecule

Indexed keywords

ANNEXIN V TC 99M; BIOLOGICAL MARKER; CASPASE; CASPASE 3; DOCETAXEL; FLUOROBENZYL TRIPHENYLPHOSPHONIUM F 18; ICMT F 18; ISATIN DERIVATIVE; ISATIN SULFONAMIDE; ML 10; ML 10 F 18; N SUCCINIMIDYL 4 FLUOROBENZOATE F 18; NST 732; NST 732 F 18; PACLITAXEL; PHOSPHATIDYLSERINE; RADIOPHARMACEUTICAL AGENT; STAUROSPORINE; UNCLASSIFIED DRUG; WC 98; WC 98 C 11; WC IV 3; WC IV 3 F 18;

ACIDIFICATION; APOPTOSIS; ATHEROSCLEROTIC PLAQUE; BRAIN ISCHEMIA; BRAIN METASTASIS; BRAIN RADIATION; BREAST CARCINOMA; CANCER CELL; CANCER RADIOTHERAPY; CELL DEATH; CELL LABELING; CELL MEMBRANE DEPOLARIZATION; CELL SPECIFICITY; CELL VIABILITY; CLINICAL TRIAL; CYTOSOL; DNA FRAGMENTATION; DOSIMETRY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; ENZYME ACTIVATION; FEASIBILITY STUDY; HEART INFARCTION; HISTOLOGY; HUMAN; IN VIVO STUDY; ISOTOPE LABELING; LUNG CARCINOGENESIS; MITOCHONDRIAL MEMBRANE POTENTIAL; PHARMACOPHORE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROSTATE TUMOR; PROTEIN BINDING; PROTEIN STRUCTURE; QUANTITATIVE ANALYSIS; REVIEW; SENSITIVITY AND SPECIFICITY; ANIMAL; METABOLISM; METHODOLOGY;

ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; CASPASES; ENZYME ACTIVATION; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; POSITRON-EMISSION TOMOGRAPHY;

EID: 77953930252     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.109.063917     Document Type: Review

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