Quantitative comparison of the sensitivity of detection of fluorescent and bioluminescent reporters in animal models

Molecular Imaging

Volumn 3, Issue 1, 2004, Pages 9-23

  Troy, Tamara ^a,b   Jekic McMullen, Dragana ^a   Sambucetti, Lidia ^a   Rice, Brad ^a  

^a Xenogen Corporation   (United States)

^b NONE   (United States)

Author keywords

Bioluminescence; Fluorescence; In vivo; Luciferase; Optical Imaging

Indexed keywords

ABSORPTION; FLUORESCENCE; IMAGING SYSTEMS; PHOTONS; PROTEINS; SCATTERING; SIGNAL TO NOISE RATIO; TISSUE;

ANIMAL CARE; IN VIVO; LUCIFERASE; OPTICAL IMAGING;

BIOLUMINESCENCE;

DIAGNOSTIC AGENT; FLUORESCENT DYE; FLUORESCENT PROTEIN 583; ORGANIC COMPOUND; PHOTOPROTEIN; PKH 26;

ADENOCARCINOMA; ANIMAL; ANIMAL MODEL; ARTICLE; COMPARATIVE STUDY; DIAGNOSTIC IMAGING; FEMALE; FLUORESCENCE; HELA CELL; HUMAN; INSTRUMENTATION; LUMINESCENCE; MALE; METABOLISM; METHODOLOGY; MOUSE; MOUSE STRAIN; NUDE MOUSE; OPTICS; PATHOLOGY; PROSTATE TUMOR; SENSITIVITY AND SPECIFICITY; TUMOR CELL LINE;

ADENOCARCINOMA; ANIMALS; CELL LINE, TUMOR; DIAGNOSTIC IMAGING; FEMALE; FLUORESCENCE; FLUORESCENT DYES; HELA CELLS; HUMANS; LUMINESCENT MEASUREMENTS; LUMINESCENT PROTEINS; MALE; MICE; MICE, INBRED STRAINS; MICE, NUDE; MODELS, ANIMAL; OPTICS; ORGANIC CHEMICALS; PROSTATIC NEOPLASMS; SENSITIVITY AND SPECIFICITY;

EID: 3042541034     PISSN: 15353508     EISSN: None     Source Type: Journal    
DOI: 10.1162/153535004773861688     Document Type: Article

References (33)

1. WT Mason, Ed. (1999). Fluorescent and luminescent probes for biological activity. London, UK: Academic Press.
2. Contag CH, Contag PR, Mullins JI, Spilman SD, Stevenson DK, Benaron DA (1995). Photonic detection of bacterial pathogens in living hosts. Mol Microbiol. 18:593-603.
3. Contag CH, Jenkins D, Contag PR, Negrin RS (2000). Use of reporter genes for optical measurements of neoplastlc disease in vivo. Neoplasia. 2:41-52.
4. Rehemtulla A, Stegman LD, Cardozo SJ, Gupta S, Hall DE, Contag CH, Ross BD (2000). Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging. Neoplasia. 2:491-495.
5. Francis KP, Yu J, Berliner C, Joh D, Hawkinson MJ, Xiao G, Purchio TF, Caparon MG, Lipsitch M, Contag PR (2001). Visualizing pneumococcal infections in the lungs of live mice using bioluminescent Streptococcus pneumoniae transformed with a novel gram-positive lux transposon. Infect Immun. 69:3350-3358.
6. Zhang W, Feng QJ, Harris SE, Contag PR, Stevenson DK, Contag CH (2001). Rapid in vivo functional analysis of transgenes in mice using whole body imaging of luciferase expression. Transgenic Res. 10:423-434.
7. Yang M, Baranov E, Jiang P, Sun F-X, Li X-M, Li L, Hasegawa S, Bouvet M, Al-Tuwaijri M, Chishima T, Shimada H, Moossa AR, Penman S, Hoffman RM (2000). Whole body optical imaging of green fluorescent protein-expressing tumors and metastases. Proc Natl Acad Sci. 97:1206-1211.
8. Bouvet M, Wang J, Nardin SR, Nassirpour R, Yang M, Baranov E, Jiang P, Moossa AR, Hoffman RM (2002). Real-time optical imaging of primary tumor growth and multiple metastatic events in a pancreatic cancer orthotopic model. Cancer Res. 62:1534-1540.
9. Weissleder R, Tung CH, Mahmood U, Boganov AJr (1999). In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol. 17:375-378.
10. Ntziachristos V, Tung CH, Bremer C, Welssleder R (2002). Fluorescence molecular tomography resolves protease activity in vivo. Nat Med. 8:757-700.
11. Wu J, Sundaresan G, Iyer M, Gambhir SS (2001). Noninvasive optical imaging of firefly luciferase reporter gene expression in skeletal muscles of living mice. Molecular Ther. 4:297-306.
12. Bhaumik S, Gambhir SS (2002). Optical imaging of renilla luciferase reporter gene expression in living mice. Proc Natl Acad Sci. 99:337-382.
13. Tuchin V (2000). Tissue optics. Bellingham, WA: SPIE Press.
14. Hawrysz DJ, Sevick-Muraca EM (2000). Developments towards diagnostic breast cancer imaging using near-infrared optical measurements of fluorescent contrast agents. Neoplasia. 2:388-417.
15. Lim YT, Kim S, Nakayama A, Stott NE, Bawendi MG, Frangioni JV (2003). Selection of quantum dot wavelengths for biomedical assays. Mol Imaging, 2:50-64.
16. Akerman ME, Chan WC, Laakkonen P, Bhatia SN, Ruoslahti E (2002). Nanocrystal targeting in vivo. Proc Natl Acad Sci. 99:12617-12621.
17. Larson DR, Zipfel WR, Williams RM, Clark SW, Bruchez MP, Wise FW, Webb WW (2003). Water-soluble quantum dots for multiphoton fluorescence imaging in vivo. Science. 300:1434-1436.
18. T Wasson-Blader, Ed. (2001). Living Colors DsRed2-1. CLONTECHniques. 16:2-3.
19. Burns SM, Joh D, Francis KP, Shortliffe LD, Gruber CA, Contag PR, Contag CH (2001). Revealing the spatiotemporal patterns of bacterial infectious diseases using bioluminescent pathogens and whole body imaging. Contrib Microbiol. 9:5737-5740.
20. Ballou B, Fisher GW, Hakala TR, Farkas DL (1997), Tumor detection and visualization using cyanine fluorochrome-labeled antibodies. Biotechol Prog. 13:649-658.
21. Reynolds JS, Troy TL, Mayer RH, Thompson AB, Waters DJ, Cornell KK, Snyder FW, Sevick-Muraca EM (1999). Imaging of spontaneous canine mammary tumors using fluorescent contrast agent. Photochem Photobiol. 70:87-94.
22. Thompson AB, Sevick-Muraca EM (2002). NIR fluorescent contrast enhanced imaging with ICCD homodyne detection; Measurement precision and accuracy. J Biomed Opt. 8:111-120.
23. Cubeddu R, Canti G, Taroni P, Valentini G (1993). Time gated fluorescence imaging for the diagnosis of tumors in murine model. Photochem Photobiol. 57:480-485.
24. Cubeddu R, Canti G, Pifferi A, Taroni P, Valentini G (1997). Fluorescent lifetime imaging of experimental tumors in hematoporphyrin derivative-sensitized mice. Photochem Photobiol. 66:229-236.
25. Cheong WF, Prahl SA, Welch AJ (1990). A review of the optical properties of biological tissues. IEEE J Quantum Electron. 26:2166-2185.
26. Ishimaru A (1978). Wave propagation and scattering in random media. New York, NY: Academic Press.
27. Haskell RC, Svaasand LO, Tsay TT, Feng TC, McAdams MS, Tromberg BJ (1994). Boundary conditions for the diffusion equation in radiative transfer. J Opt Soc Am A 11:2727-2741.
28. Jacques SL (1995). Tissue fluorescence. In DA Cortese (Ed.), Proceedings of SPIE Volume 2371: 5th International Photodynamic Association Biennial Meeting (pp. 2-13). Bellingham, WA.
29. Rice BW, Cable MD, Nelson MB (2001). In vivo imaging of light emitting probes. J Biomed Opt. 6:432-440.
30. Wolfe WL (1998). Introduction to radiometry. Bellingham, WA: SPIE Optical Engineering Press.
31. Billinton N, Knight AW (2001). Seeing the wood through the trees: A review of techniques for distinguishing green fluorescent protein from endogenous autofluorescence. Anal Biochem. 291:175-197.
32. Shorte SL, Bolsover S (1999). Imaging reality: Understanding maps of physiological cell signals measured by fluorescent microscopy and digital imaging. In WT Mason (Ed.), Fluorescent and luminescent probes for biological activity (pp. 95-107). London, UK.
33. Farkas DL, Du C, Fisher GW, Lau C, Niu W, Wachman ES, Levenson RM (1998). Non-invasive image acquisition and advanced processing in optical bioimaging. Comput Med Imaging Graph. 22:89-102.