Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis

Nature

Volumn 464, Issue 7291, 2010, Pages 1058-1061

  Zhang, Ling ^a   Ren, Xiaoyang ^a   Alt, Eckhard ^a   Bai, Xiaowen ^a   Huang, Shaoyi ^a   Xu, Zhengming ^a   Lynch, Patrick M ^a   Moyer, Mary P ^b   Wen, Xian Feng ^a   Wu, Xiangwei ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b INCELL Corporation ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; BETA CATENIN; DEATH RECEPTOR 5; FLICE INHIBITORY PROTEIN; MYC PROTEIN; RETINOL ACETATE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR 3;

ACETATE; APOPTOSIS; CANCER; CARCINOGEN; CYTOLOGY; DISEASE CONTROL; DISEASE TREATMENT; LIGAND; MEDICINE; TUMOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER MODEL; CANCER PREVENTION; CANCER SURVIVAL; CELL DEATH; CHEMOPROPHYLAXIS; COLORECTAL CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; GENE ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INTESTINE POLYP; MALE; MOUSE; MULTIPLE CYCLE TREATMENT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TARGET CELL; TREATMENT OUTCOME; TUMOR CELL; UPREGULATION;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; APOPTOSIS; BETA CATENIN; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CELL PROLIFERATION; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION; GENES, APC; HUMANS; INTESTINAL POLYPS; MICE; MICE, INBRED C57BL; PRECANCEROUS CONDITIONS; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; SIGNAL TRANSDUCTION; SURVIVAL RATE; TIME FACTORS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; VITAMIN A;

MUS;

EID: 77951134107     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature08871     Document Type: Article

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