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Volumn 3, Issue 3, 2013, Pages 190-200

Longitudinal bioluminescence imaging of the dynamics of doxorubicin induced apoptosis

Author keywords

Apoptosis; Bioluminescence imaging; Caspase 3; Cyclic firefly luciferase; Doxorubicin

Indexed keywords

CASPASE 3; DOXORUBICIN; FIREFLY LUCIFERASE; LIPOCORTIN 5; ANTINEOPLASTIC AGENT;

EID: 84882947458     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.5825     Document Type: Article
Times cited : (39)

References (48)
  • 1
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • doi:10.1038/35037710
    • Hengartner MO. The biochemistry of apoptosis. Nature. 2000; 407: 770-6. doi:10.1038/35037710.
    • (2000) Nature. , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 2
    • 34250308322 scopus 로고    scopus 로고
    • Apoptosis: a review of programmed cell death
    • doi:779478428 [pii]10.1080/01926230701320337
    • Elmore S. Apoptosis: a review of programmed cell death. Toxicol Pathol. 2007; 35: 495-516. doi:779478428 [pii]10.1080/01926230701320337.
    • (2007) Toxicol Pathol. , vol.35 , pp. 495-516
    • Elmore, S.1
  • 3
    • 0036547417 scopus 로고    scopus 로고
    • Death and anti-death: tumour resistance to apoptosis
    • doi:10.1038/nrc776
    • Igney FH, Krammer PH. Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer. 2002; 2: 277-88. doi:10.1038/nrc776.
    • (2002) Nat Rev Cancer , vol.2 , pp. 277-288
    • Igney, F.H.1    Krammer, P.H.2
  • 4
    • 28544443984 scopus 로고    scopus 로고
    • Promoting apoptosis as a strategy for cancer drug discovery
    • doi:nrc1736 [pii]10.1038/nrc1736
    • Fesik SW. Promoting apoptosis as a strategy for cancer drug discovery. Nat Rev Cancer. 2005; 5: 876-85. doi:nrc1736 [pii]10.1038/nrc1736.
    • (2005) Nat Rev Cancer , vol.5 , pp. 876-885
    • Fesik, S.W.1
  • 5
    • 0037169358 scopus 로고    scopus 로고
    • Apoptosis: a link between cancer genetics and chemotherapy
    • doi:S0092867402006256 [pii]
    • Johnstone RW, Ruefli AA, Lowe SW. Apoptosis: a link between cancer genetics and chemotherapy. Cell. 2002; 108: 153-64. doi:S0092867402006256 [pii].
    • (2002) Cell , vol.108 , pp. 153-164
    • Johnstone, R.W.1    Ruefli, A.A.2    Lowe, S.W.3
  • 6
    • 0034630167 scopus 로고    scopus 로고
    • Induction of apoptosis by cancer chemotherapy
    • doi:10.1006/excr.2000.4838S0014-4827(00)94838-9 [pii]
    • Kaufmann SH, Earnshaw WC. Induction of apoptosis by cancer chemotherapy. Exp Cell Res. 2000; 256: 42-9. doi:10.1006/excr.2000.4838S0014-4827(00)94838-9 [pii].
    • (2000) Exp Cell Res. , vol.256 , pp. 42-49
    • Kaufmann, S.H.1    Earnshaw, W.C.2
  • 8
    • 42249103253 scopus 로고    scopus 로고
    • Noninvasive imaging of apoptosis and its application in cancer therapeutics
    • doi:14/8/2492 [pii]10.1158/1078-0432.CCR-07-0782
    • Coppola JM, Ross BD, Rehemtulla A. Noninvasive imaging of apoptosis and its application in cancer therapeutics. Clin Cancer Res. 2008; 14: 2492-501. doi:14/8/2492 [pii]10.1158/1078-0432.CCR-07-0782.
    • (2008) Clin Cancer Res. , vol.14 , pp. 2492-2501
    • Coppola, J.M.1    Ross, B.D.2    Rehemtulla, A.3
  • 10
    • 70349650786 scopus 로고    scopus 로고
    • Live-cell imaging of caspase activation for high-content screening
    • doi:1087057109343207 [pii]10.1177/1087057109343207
    • Antczak C, Takagi T, Ramirez CN, Radu C, Djaballah H. Live-cell imaging of caspase activation for high-content screening. J Biomol Screen. 2009; 14: 956-69. doi:1087057109343207 [pii]10.1177/1087057109343207.
    • (2009) J Biomol Screen , vol.14 , pp. 956-969
    • Antczak, C.1    Takagi, T.2    Ramirez, C.N.3    Radu, C.4    Djaballah, H.5
  • 11
    • 84864544057 scopus 로고    scopus 로고
    • In vivo monitoring of liver damage using caspase-3 probe
    • doi:10.7150/thno.3806
    • Ozaki M, Haga S, Ozawa T. In vivo monitoring of liver damage using caspase-3 probe. Theranostics. 2012; 2: 207-14. doi:10.7150/thno.3806.
    • (2012) Theranostics , vol.2 , pp. 207-214
    • Ozaki, M.1    Haga, S.2    Ozawa, T.3
  • 12
    • 78649908356 scopus 로고    scopus 로고
    • Functional nanoparticles for molecular imaging guided gene delivery
    • Liu G, Swierczewska M, Lee S, Chen X. Functional nanoparticles for molecular imaging guided gene delivery. Nano Today. 2010; 5: 524-39.
    • (2010) Nano Today , vol.5 , pp. 524-539
    • Liu, G.1    Swierczewska, M.2    Lee, S.3    Chen, X.4
  • 13
    • 79952688105 scopus 로고    scopus 로고
    • Molecular imaging of cell-based cancer immunotherapy
    • doi:10.1039/c0mb00198h
    • Liu G, Swierczewska M, Niu G, Zhang X, Chen X. Molecular imaging of cell-based cancer immunotherapy. Mol Biosyst. 2011;7:993-1003. doi:10.1039/c0mb00198h.
    • (2011) Mol Biosyst , vol.7 , pp. 993-1003
    • Liu, G.1    Swierczewska, M.2    Niu, G.3    Zhang, X.4    Chen, X.5
  • 14
    • 77951564318 scopus 로고    scopus 로고
    • MR imaging for the longevity of mesenchymal stem cells labeled with poly-L-lysine-Resovist complexes
    • doi:10.1002/cmmi.362
    • Liu G, Yang H, Zhang XM, Shao Y, Jiang H. MR imaging for the longevity of mesenchymal stem cells labeled with poly-L-lysine-Resovist complexes. Contrast Media Mol Imaging. 2010;5: 53-8. doi:10.1002/cmmi.362.
    • (2010) Contrast Media Mol Imaging. , vol.5 , pp. 53-58
    • Liu, G.1    Yang, H.2    Zhang, X.M.3    Shao, Y.4    Jiang, H.5
  • 15
    • 2342518172 scopus 로고    scopus 로고
    • Multimodality noninvasive imaging of gene transfer using the human sodium iodide symporter
    • Niu G, Gaut AW, Ponto LL, Hichwa RD, Madsen MT, Graham MM, et al. Multimodality noninvasive imaging of gene transfer using the human sodium iodide symporter. J Nucl Med. 2004; 45: 445-9.
    • (2004) J Nucl Med. , vol.45 , pp. 445-449
    • Niu, G.1    Gaut, A.W.2    Ponto, L.L.3    Hichwa, R.D.4    Madsen, M.T.5    Graham, M.M.6
  • 16
  • 17
    • 77952236479 scopus 로고    scopus 로고
    • Noninvasive molecular imaging of apoptosis in vivo using a modified firefly luciferase substrate, Z-DEVD-aminoluciferin
    • doi:cdd2009205 [pii]10.1038/cdd.2009.205
    • Hickson J, Ackler S, Klaubert D, Bouska J, Ellis P, Foster K, et al. Noninvasive molecular imaging of apoptosis in vivo using a modified firefly luciferase substrate, Z-DEVD-aminoluciferin. Cell Death Differ. 2010; 17: 1003-10. doi:cdd2009205 [pii]10.1038/cdd.2009.205.
    • (2010) Cell Death Differ. , vol.17 , pp. 1003-1010
    • Hickson, J.1    Ackler, S.2    Klaubert, D.3    Bouska, J.4    Ellis, P.5    Foster, K.6
  • 19
    • 39449139103 scopus 로고    scopus 로고
    • Linking proteins with anionic nanoparticles via protamine: ultrasmall protein-coupled probes for magnetic resonance imaging of apoptosis
    • doi:10.1002/smll.200700847
    • Schellenberger E, Schnorr J, Reutelingsperger C, Ungethum L, Meyer W, Taupitz M, et al. Linking proteins with anionic nanoparticles via protamine: ultrasmall protein-coupled probes for magnetic resonance imaging of apoptosis. Small. 2008; 4: 225-30. doi:10.1002/smll.200700847.
    • (2008) Small. , vol.4 , pp. 225-230
    • Schellenberger, E.1    Schnorr, J.2    Reutelingsperger, C.3    Ungethum, L.4    Meyer, W.5    Taupitz, M.6
  • 20
    • 34250219265 scopus 로고    scopus 로고
    • Noninvasive molecular imaging sheds light on the synergy between 5-fluorouracil and TRAIL/Apo2L for cancer therapy
    • doi:13/6/1839 [pii]10.1158/1078-0432.CCR-06-1657
    • Lee KC, Hamstra DA, Bhojani MS, Khan AP, Ross BD, Rehemtulla A. Noninvasive molecular imaging sheds light on the synergy between 5-fluorouracil and TRAIL/Apo2L for cancer therapy. Clin Cancer Res. 2007; 13: 1839-46. doi:13/6/1839 [pii]10.1158/1078-0432.CCR-06-1657.
    • (2007) Clin Cancer Res. , vol.13 , pp. 1839-1846
    • Lee, K.C.1    Hamstra, D.A.2    Bhojani, M.S.3    Khan, A.P.4    Ross, B.D.5    Rehemtulla, A.6
  • 21
    • 59149092095 scopus 로고    scopus 로고
    • Multiparametric monitoring of tumor response to chemotherapy by noninvasive imaging
    • doi:0008-5472.CAN-08-2001 [pii]10.1158/0008-5472.CAN-08-2001
    • Medarova Z, Rashkovetsky L, Pantazopoulos P, Moore A. Multiparametric monitoring of tumor response to chemotherapy by noninvasive imaging. Cancer Res. 2009; 69: 1182-9. doi:0008-5472.CAN-08-2001 [pii]10.1158/0008-5472.CAN-08-2001.
    • (2009) Cancer Res. , vol.69 , pp. 1182-1189
    • Medarova, Z.1    Rashkovetsky, L.2    Pantazopoulos, P.3    Moore, A.4
  • 22
    • 69249211282 scopus 로고    scopus 로고
    • Imaging the molecular signatures of apoptosis and injury with radiolabeled annexin V
    • doi:6/5/469 [pii]10.1513/pats.200901-001AW
    • Blankenberg FG. Imaging the molecular signatures of apoptosis and injury with radiolabeled annexin V. Proc Am Thorac Soc. 2009; 6: 469-76. doi:6/5/469 [pii]10.1513/pats.200901-001AW.
    • (2009) Proc Am Thorac Soc. , vol.6 , pp. 469-476
    • Blankenberg, F.G.1
  • 23
    • 79551513175 scopus 로고    scopus 로고
    • Molecular imaging in cancer treatment
    • doi:10.1007/s00259-010-1569-z
    • Michalski MH, Chen X. Molecular imaging in cancer treatment. Eur J Nucl Med Mol Imaging. 2009;38: 358-77. doi:10.1007/s00259-010-1569-z.
    • (2009) Eur J Nucl Med Mol Imaging. , vol.38 , pp. 358-377
    • Michalski, M.H.1    Chen, X.2
  • 24
    • 79851482376 scopus 로고    scopus 로고
    • Apoptosis imaging: beyond annexin V
    • doi:jnumed.110.078584 [pii]10.2967/jnumed.110.078584
    • Niu G, Chen X. Apoptosis imaging: beyond annexin V. J Nucl Med. 2010; 51: 1659-62. doi:jnumed.110.078584 [pii]10.2967/jnumed.110.078584.
    • (2010) J Nucl Med. , vol.51 , pp. 1659-1662
    • Niu, G.1    Chen, X.2
  • 25
    • 78751547461 scopus 로고    scopus 로고
    • Engineered annexin a5 variants have impaired cell entry for molecular imaging of apoptosis using pretargeting strategies
    • doi:M110.163527 [pii]10.1074/jbc.M110.163527
    • Ungethum L, Kenis H, Nicolaes GA, Autin L, Stoilova-McPhie S, Reutelingsperger CP. Engineered annexin a5 variants have impaired cell entry for molecular imaging of apoptosis using pretargeting strategies. J Biol Chem. 2011; 286: 1903-10. doi:M110.163527 [pii]10.1074/jbc.M110.163527.
    • (2011) J Biol Chem. , vol.286 , pp. 1903-1910
    • Ungethum, L.1    Kenis, H.2    Nicolaes, G.A.3    Autin, L.4    Stoilova-McPhie, S.5    Reutelingsperger, C.P.6
  • 26
    • 0032785021 scopus 로고    scopus 로고
    • Caspase structure, proteolytic substrates, and function during apoptotic cell death
    • doi:10.1038/sj.cdd.4400598
    • Nicholson DW. Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Differ. 1999; 6: 1028-42. doi:10.1038/sj.cdd.4400598.
    • (1999) Cell Death Differ. , vol.6 , pp. 1028-1042
    • Nicholson, D.W.1
  • 27
    • 84864566024 scopus 로고    scopus 로고
    • Theranostic Imaging of the Kinases and Proteases that Modulate Cell Death and Survival
    • doi:10.7150/thno.4077
    • Chen HH, Yuan H, Josephson L, Sosnovik DE. Theranostic Imaging of the Kinases and Proteases that Modulate Cell Death and Survival. Theranostics. 2012; 2: 148-55. doi:10.7150/thno.4077.
    • (2012) Theranostics , vol.2 , pp. 148-155
    • Chen, H.H.1    Yuan, H.2    Josephson, L.3    Sosnovik, D.E.4
  • 29
    • 33645403885 scopus 로고    scopus 로고
    • Cell-permeable and biocompatible polymeric nanoparticles for apoptosis imaging
    • Kim K, Lee M, Park H, Kim JH, Kim S, Chung H, et al. Cell-permeable and biocompatible polymeric nanoparticles for apoptosis imaging. J Am Chem Soc. 2006; 128: 3490-1.
    • (2006) J Am Chem Soc. , vol.128 , pp. 3490-3491
    • Kim, K.1    Lee, M.2    Park, H.3    Kim, J.H.4    Kim, S.5    Chung, H.6
  • 30
    • 33645419086 scopus 로고    scopus 로고
    • A fluorescent nanosensor for apoptotic cells
    • Quinti L, Weissleder R, Tung CH. A fluorescent nanosensor for apoptotic cells. Nano Lett. 2006; 6: 488-90.
    • (2006) Nano Lett. , vol.6 , pp. 488-490
    • Quinti, L.1    Weissleder, R.2    Tung, C.H.3
  • 31
    • 67249095097 scopus 로고    scopus 로고
    • Single-cell imaging of retinal ganglion cell apoptosis with a cell-penetrating, activatable peptide probe in an in vivo glaucoma model
    • Barnett EM, Zhang X, Maxwell D, Chang Q, Piwnica-Worms D. Single-cell imaging of retinal ganglion cell apoptosis with a cell-penetrating, activatable peptide probe in an in vivo glaucoma model. Proc Natl Acad Sci U S A. 2009; 106: 9391-6.
    • (2009) Proc Natl Acad Sci U S A. , vol.106 , pp. 9391-9396
    • Barnett, E.M.1    Zhang, X.2    Maxwell, D.3    Chang, Q.4    Piwnica-Worms, D.5
  • 33
    • 53249155162 scopus 로고    scopus 로고
    • Monitoring caspase-3 activation with a multimodality imaging sensor in living subjects
    • doi:14/18/5801 [pii]10.1158/1078-0432.CCR-07-5244
    • Ray P, De A, Patel M, Gambhir SS. Monitoring caspase-3 activation with a multimodality imaging sensor in living subjects. Clin Cancer Res. 2008; 14: 5801-9. doi:14/18/5801 [pii]10.1158/1078-0432.CCR-07-5244.
    • (2008) Clin Cancer Res. , vol.14 , pp. 5801-5809
    • Ray, P.1    De, A.2    Patel, M.3    Gambhir, S.S.4
  • 34
    • 35048844611 scopus 로고    scopus 로고
    • Cyclic luciferase for real-time sensing of caspase-3 activities in living mammals
    • doi:10.1002/anie.200700538
    • Kanno A, Yamanaka Y, Hirano H, Umezawa Y, Ozawa T. Cyclic luciferase for real-time sensing of caspase-3 activities in living mammals. Angew Chem Int Ed Engl. 2007; 46: 7595-9. doi:10.1002/anie.200700538.
    • (2007) Angew Chem Int Ed Engl. , vol.46 , pp. 7595-7599
    • Kanno, A.1    Yamanaka, Y.2    Hirano, H.3    Umezawa, Y.4    Ozawa, T.5
  • 35
    • 84934439113 scopus 로고    scopus 로고
    • Detection of apoptosis using cyclic luciferase in living mammals
    • doi:10.1007/978-1-60327-321-3_9
    • Kanno A, Umezawa Y, Ozawa T. Detection of apoptosis using cyclic luciferase in living mammals. Methods Mol Biol. 2009; 574: 105-14. doi:10.1007/978-1-60327-321-3_9.
    • (2009) Methods Mol Biol. , vol.574 , pp. 105-114
    • Kanno, A.1    Umezawa, Y.2    Ozawa, T.3
  • 36
    • 78449251127 scopus 로고    scopus 로고
    • Low molecular weight alkyl-polycation wrapped magnetite nanoparticle clusters as MRI probes for stem cell labeling and in vivo imaging
    • doi:S0142-9612(10)01137-3 [pii]10.1016/j.biomaterials.2010.08.099
    • Liu G, Wang Z, Lu J, Xia C, Gao F, Gong Q, et al. Low molecular weight alkyl-polycation wrapped magnetite nanoparticle clusters as MRI probes for stem cell labeling and in vivo imaging. Biomaterials. 2011; 32: 528-37. doi:S0142-9612(10)01137-3 [pii]10.1016/j.biomaterials.2010.08.099.
    • (2011) Biomaterials. , vol.32 , pp. 528-537
    • Liu, G.1    Wang, Z.2    Lu, J.3    Xia, C.4    Gao, F.5    Gong, Q.6
  • 37
    • 76649112052 scopus 로고    scopus 로고
    • Preparation of the caspase-3/7 substrate Ac-DEVD-pNA by solution-phase peptide synthesis
    • Peterson QP, Goode DR, West DC, Botham RC, Hergenrother PJ. Preparation of the caspase-3/7 substrate Ac-DEVD-pNA by solution-phase peptide synthesis. Nat Protoc. 2010;5: 294-302.
    • (2010) Nat Protoc. , vol.5 , pp. 294-302
    • Peterson, Q.P.1    Goode, D.R.2    West, D.C.3    Botham, R.C.4    Hergenrother, P.J.5
  • 39
    • 0035902115 scopus 로고    scopus 로고
    • Proliferation, cell cycle and apoptosis in cancer
    • Evan GI, Vousden KH. Proliferation, cell cycle and apoptosis in cancer. Nature. 2001; 411: 342-8.
    • (2001) Nature. , vol.411 , pp. 342-348
    • Evan, G.I.1    Vousden, K.H.2
  • 40
    • 0019501881 scopus 로고
    • The anthracycline antineoplastic drugs
    • doi:10.1056/NEJM198107163050305
    • Young RC, Ozols RF, Myers CE. The anthracycline antineoplastic drugs. N Engl J Med. 1981; 305: 139-53. doi:10.1056/NEJM198107163050305.
    • (1981) N Engl J Med. , vol.305 , pp. 139-153
    • Young, R.C.1    Ozols, R.F.2    Myers, C.E.3
  • 41
    • 0021151237 scopus 로고
    • Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II
    • Tewey KM, Rowe TC, Yang L, Halligan BD, Liu LF. Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II. Science. 1984; 226: 466-8.
    • (1984) Science. , vol.226 , pp. 466-468
    • Tewey, K.M.1    Rowe, T.C.2    Yang, L.3    Halligan, B.D.4    Liu, L.F.5
  • 42
    • 0025283897 scopus 로고
    • Doxorubicin (adriamycin): a critical review of free radical-dependent mechanisms of cytotoxicity
    • doi:0163-7258(90)90088-J [pii]
    • Keizer HG, Pinedo HM, Schuurhuis GJ, Joenje H. Doxorubicin (adriamycin): a critical review of free radical-dependent mechanisms of cytotoxicity. Pharmacol Ther. 1990; 47: 219-31. doi:0163-7258(90)90088-J [pii].
    • (1990) Pharmacol Ther. , vol.47 , pp. 219-231
    • Keizer, H.G.1    Pinedo, H.M.2    Schuurhuis, G.J.3    Joenje, H.4
  • 43
    • 0028911724 scopus 로고
    • Kinetics of cisplatin-induced apoptosis in murine mammary and ovarian adenocarcinomas
    • Meyn RE, Stephens LC, Hunter NR, Milas L. Kinetics of cisplatin-induced apoptosis in murine mammary and ovarian adenocarcinomas. Int J Cancer. 1995; 60: 725-9.
    • (1995) Int J Cancer. , vol.60 , pp. 725-729
    • Meyn, R.E.1    Stephens, L.C.2    Hunter, N.R.3    Milas, L.4
  • 44
    • 22244460493 scopus 로고    scopus 로고
    • Dose and time dependent apoptotic response in a human melanoma cell line exposed to accelerated boron ions at four different LET
    • doi:V434316V52P16420 [pii]10.1080/09553000500141215
    • Meijer AE, Jernberg AR, Heiden T, Stenerlow B, Persson LM, Tilly N, et al. Dose and time dependent apoptotic response in a human melanoma cell line exposed to accelerated boron ions at four different LET. Int J Radiat Biol. 2005; 81: 261-72. doi:V434316V52P16420 [pii]10.1080/09553000500141215.
    • (2005) Int J Radiat Biol. , vol.81 , pp. 261-272
    • Meijer, A.E.1    Jernberg, A.R.2    Heiden, T.3    Stenerlow, B.4    Persson, L.M.5    Tilly, N.6
  • 45
    • 77952295284 scopus 로고    scopus 로고
    • Time course of Paclitaxel-induced apoptosis in an experimental model of virus-induced breast cancer
    • doi:jnumed.109.071621 [pii]10.2967/jnumed.109.071621
    • Erba PA, Manfredi C, Lazzeri E, Minichilli F, Pauwels EK, Sbrana A, et al. Time course of Paclitaxel-induced apoptosis in an experimental model of virus-induced breast cancer. J Nucl Med. 2010; 51: 775-81. doi:jnumed.109.071621 [pii]10.2967/jnumed.109.071621.
    • (2010) J Nucl Med. , vol.51 , pp. 775-781
    • Erba, P.A.1    Manfredi, C.2    Lazzeri, E.3    Minichilli, F.4    Pauwels, E.K.5    Sbrana, A.6
  • 46
    • 79951575617 scopus 로고    scopus 로고
    • In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation
    • doi: 10.1007/s10495-010-0553-1
    • Scabini M, Stellari F, Cappella P, Rizzitano S, Texido G, Pesenti E. In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation. Apoptosis. 2011;16:198-207. doi: 10.1007/s10495-010-0553-1.
    • (2011) Apoptosis. , vol.16 , pp. 198-207
    • Scabini, M.1    Stellari, F.2    Cappella, P.3    Rizzitano, S.4    Texido, G.5    Pesenti, E.6
  • 47
    • 1842592126 scopus 로고    scopus 로고
    • Imaging taxane-induced tumor apoptosis using PEGylated, 111In-labeled annexin V
    • Ke S, Wen X, Wu QP, Wallace S, Charnsangavej C, Stachowiak AM, et al. Imaging taxane-induced tumor apoptosis using PEGylated, 111In-labeled annexin V. J Nucl Med. 2004; 45: 108-15.
    • (2004) J Nucl Med. , vol.45 , pp. 108-115
    • Ke, S.1    Wen, X.2    Wu, Q.P.3    Wallace, S.4    Charnsangavej, C.5    Stachowiak, A.M.6
  • 48
    • 84870455411 scopus 로고    scopus 로고
    • Longitudinal PET imaging of doxorubicin-induced cell death with 18F-Annexin V
    • doi:10.1007/s11307-012-0551-5
    • Hu S, Kiesewetter DO, Zhu L, Guo N, Gao H, Liu G, et al. Longitudinal PET imaging of doxorubicin-induced cell death with 18F-Annexin V. Mol Imaging Biol. 2012; 14: 762-70. doi:10.1007/s11307-012-0551-5
    • (2012) Mol Imaging Biol. , vol.14 , pp. 762-770
    • Hu, S.1    Kiesewetter, D.O.2    Zhu, L.3    Guo, N.4    Gao, H.5    Liu, G.6


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