-
1
-
-
84901195744
-
Alpha-tryptase gene variation is associated with levels of circulating IgE and lung function in asthma
-
A.M. Abdelmotelb, M.J. Rose-Zerilli, S.J. Barton, S. Holgate, A.F. Walls, and J.W. Holloway Alpha-tryptase gene variation is associated with levels of circulating IgE and lung function in asthma Clin. Exp. Allergy 44 2014 822 830
-
(2014)
Clin. Exp. Allergy
, vol.44
, pp. 822-830
-
-
Abdelmotelb, A.M.1
Rose-Zerilli, M.J.2
Barton, S.J.3
Holgate, S.4
Walls, A.F.5
Holloway, J.W.6
-
2
-
-
77953962851
-
Involvement of mast cells in eosinophilic esophagitis
-
J.P. Abonia, C. Blanchard, B.B. Butz, H.F. Rainey, M.H. Collins, K. Stringer, P.E. Putnam, and M.E. Rothenberg Involvement of mast cells in eosinophilic esophagitis J. Allergy Clin. Immunol. 126 2010 140 149
-
(2010)
J. Allergy Clin. Immunol.
, vol.126
, pp. 140-149
-
-
Abonia, J.P.1
Blanchard, C.2
Butz, B.B.3
Rainey, H.F.4
Collins, M.H.5
Stringer, K.6
Putnam, P.E.7
Rothenberg, M.E.8
-
3
-
-
21044433149
-
Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle
-
J.P. Abonia, D.S. Friend, W.G. Austen Jr., F.D. Moore Jr., M.C. Carroll, R. Chan, J. Afnan, A. Humbles, C. Gerard, P. Knight, Y. Kanaoka, S. Yasuda, N. Morokawa, K.F. Austen, R.L. Stevens, and M.F. Gurish Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle J. Immunol. 174 2005 7285 7291
-
(2005)
J. Immunol.
, vol.174
, pp. 7285-7291
-
-
Abonia, J.P.1
Friend, D.S.2
Austen, W.G.3
Moore, F.D.4
Carroll, M.C.5
Chan, R.6
Afnan, J.7
Humbles, A.8
Gerard, C.9
Knight, P.10
Kanaoka, Y.11
Yasuda, S.12
Morokawa, N.13
Austen, K.F.14
Stevens, R.L.15
Gurish, M.F.16
-
4
-
-
0036168150
-
Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis
-
A.M. Adkison, S.Z. Raptis, D.G. Kelley, and C.T. Pham Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis J. Clin. Invest. 109 2002 363 371
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 363-371
-
-
Adkison, A.M.1
Raptis, S.Z.2
Kelley, D.G.3
Pham, C.T.4
-
5
-
-
80053429380
-
Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice
-
M. Akahoshi, C.H. Song, A.M. Piliponsky, M. Metz, A. Guzzetta, M. Abrink, S.M. Schlenner, T.B. Feyerabend, H.R. Rodewald, G. Pejler, M. Tsai, and S.J. Galli Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice J. Clin. Invest. 121 2011 4180 4191
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 4180-4191
-
-
Akahoshi, M.1
Song, C.H.2
Piliponsky, A.M.3
Metz, M.4
Guzzetta, A.5
Abrink, M.6
Schlenner, S.M.7
Feyerabend, T.B.8
Rodewald, H.R.9
Pejler, G.10
Tsai, M.11
Galli, S.J.12
-
6
-
-
34249285859
-
Tryptase haplotype in mastocytosis: Relationship to disease variant and diagnostic utility of total tryptase levels
-
C. Akin, D. Soto, E. Brittain, A. Chhabra, L.B. Schwartz, G.H. Caughey, and D.D. Metcalfe Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels Clin. Immunol. 123 2007 268 271
-
(2007)
Clin. Immunol.
, vol.123
, pp. 268-271
-
-
Akin, C.1
Soto, D.2
Brittain, E.3
Chhabra, A.4
Schwartz, L.B.5
Caughey, G.H.6
Metcalfe, D.D.7
-
7
-
-
58049213898
-
The extended substrate specificity of the human mast cell chymase reveals a serine protease with well-defined substrate recognition profile
-
M.K. Andersson, M. Enoksson, M. Gallwitz, and L. Hellman The extended substrate specificity of the human mast cell chymase reveals a serine protease with well-defined substrate recognition profile Int. Immunol. 21 2009 95 104
-
(2009)
Int. Immunol.
, vol.21
, pp. 95-104
-
-
Andersson, M.K.1
Enoksson, M.2
Gallwitz, M.3
Hellman, L.4
-
8
-
-
15944362722
-
Relationship of small airway chymase-positive mast cells and lung function in severe asthma
-
S. Balzar, H.W. Chu, M. Strand, and S. Wenzel Relationship of small airway chymase-positive mast cells and lung function in severe asthma Am. J. Respir. Crit. Care Med. 171 2005 431 439
-
(2005)
Am. J. Respir. Crit. Care Med.
, vol.171
, pp. 431-439
-
-
Balzar, S.1
Chu, H.W.2
Strand, M.3
Wenzel, S.4
-
9
-
-
79551511756
-
Mast cell phenotype, location and activation in severe asthma. Data from the severe asthma research program
-
S. Balzar, M.L. Fajt, S.A. Comhair, S.C. Erzurum, E. Bleecker, W.W. Busse, M. Castro, B. Gaston, E. Israel, L.B. Schwartz, D. Curran-Everett, C.G. Moore, and S.E. Wenzel Mast cell phenotype, location and activation in severe asthma. Data from the severe asthma research program Am. J. Respir. Crit. Care Med. 183 2011 299 309
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.183
, pp. 299-309
-
-
Balzar, S.1
Fajt, M.L.2
Comhair, S.A.3
Erzurum, S.C.4
Bleecker, E.5
Busse, W.W.6
Castro, M.7
Gaston, B.8
Israel, E.9
Schwartz, L.B.10
Curran-Everett, D.11
Moore, C.G.12
Wenzel, S.E.13
-
10
-
-
84875224340
-
A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis
-
E.L. Beckett, R.L. Stevens, A.G. Jarnicki, R.Y. Kim, I. Hanish, N.G. Hansbro, A. Deane, S. Keely, J.C. Horvat, M. Yang, B.G. Oliver, N. van Rooijen, M.D. Inman, R. Adachi, R.J. Soberman, S. Hamadi, P.A. Wark, P.S. Foster, and P.M. Hansbro A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis J. Allergy Clin. Immunol. 131 2013 752 762
-
(2013)
J. Allergy Clin. Immunol.
, vol.131
, pp. 752-762
-
-
Beckett, E.L.1
Stevens, R.L.2
Jarnicki, A.G.3
Kim, R.Y.4
Hanish, I.5
Hansbro, N.G.6
Deane, A.7
Keely, S.8
Horvat, J.C.9
Yang, M.10
Oliver, B.G.11
Van Rooijen, N.12
Inman, M.D.13
Adachi, R.14
Soberman, R.J.15
Hamadi, S.16
Wark, P.A.17
Foster, P.S.18
Hansbro, P.M.19
-
11
-
-
13044313485
-
Potent selective nonpeptidic inhibitors of human lung tryptase
-
L.E. Burgess, B.J. Newhouse, P. Ibrahim, J. Rizzi, M.A. Kashem, A. Hartman, B.J. Brandhuber, C.D. Wright, D.S. Thomson, G.P. Vigers, and K. Koch Potent selective nonpeptidic inhibitors of human lung tryptase Proc. Natl. Acad. Sci. USA 96 1999 8348 8352
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 8348-8352
-
-
Burgess, L.E.1
Newhouse, B.J.2
Ibrahim, P.3
Rizzi, J.4
Kashem, M.A.5
Hartman, A.6
Brandhuber, B.J.7
Wright, C.D.8
Thomson, D.S.9
Vigers, G.P.10
Koch, K.11
-
12
-
-
10644257614
-
Inhibitors of mast cell tryptase beta as therapeutics for the treatment of asthma and inflammatory disorders
-
J.A. Cairns Inhibitors of mast cell tryptase beta as therapeutics for the treatment of asthma and inflammatory disorders Pulm. Pharmacol. Ther. 18 2005 55 66
-
(2005)
Pulm. Pharmacol. Ther.
, vol.18
, pp. 55-66
-
-
Cairns, J.A.1
-
13
-
-
11844255723
-
Genetic insights into mast cell chymase and tryptase function
-
G.H. Caughey Genetic insights into mast cell chymase and tryptase function Clin. Exp. Allergy Rev. 4 2004 96 101
-
(2004)
Clin. Exp. Allergy Rev.
, vol.4
, pp. 96-101
-
-
Caughey, G.H.1
-
14
-
-
33646911804
-
Tryptase genetics and anaphylaxis
-
G.H. Caughey Tryptase genetics and anaphylaxis J. Allergy Clin. Immunol. 117 2006 1411 1414
-
(2006)
J. Allergy Clin. Immunol.
, vol.117
, pp. 1411-1414
-
-
Caughey, G.H.1
-
15
-
-
34248140140
-
Mast cell tryptases and chymases in inflammation and host defense
-
G.H. Caughey Mast cell tryptases and chymases in inflammation and host defense Immunol. Rev. 217 2007 141 154
-
(2007)
Immunol. Rev.
, vol.217
, pp. 141-154
-
-
Caughey, G.H.1
-
16
-
-
79960926555
-
Mast cell proteases as protective and inflammatory mediators
-
G.H. Caughey Mast cell proteases as protective and inflammatory mediators Adv. Exp. Med. Biol. 716 2011 212 234
-
(2011)
Adv. Exp. Med. Biol.
, vol.716
, pp. 212-234
-
-
Caughey, G.H.1
-
17
-
-
46649111783
-
Guinea pig chymase is leucine-specific: A novel example of functional plasticity in the chymase/granzyme family of serine peptidases
-
G.H. Caughey, J. Beauchamp, D. Schlatter, W.W. Raymond, N.N. Trivedi, D. Banner, H. Mauser, and J. Fingerle Guinea pig chymase is leucine-specific: a novel example of functional plasticity in the chymase/granzyme family of serine peptidases J. Biol. Chem. 283 2008 13943 13951
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13943-13951
-
-
Caughey, G.H.1
Beauchamp, J.2
Schlatter, D.3
Raymond, W.W.4
Trivedi, N.N.5
Banner, D.6
Mauser, H.7
Fingerle, J.8
-
18
-
-
0023875638
-
Substance P and vasoactive intestinal peptide degradation by mast cell tryptase and chymase
-
G.H. Caughey, F. Leidig, N.F. Viro, and J.A. Nadel Substance P and vasoactive intestinal peptide degradation by mast cell tryptase and chymase J. Pharmacol. Exp. Ther. 244 1988 133 137
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.244
, pp. 133-137
-
-
Caughey, G.H.1
Leidig, F.2
Viro, N.F.3
Nadel, J.A.4
-
19
-
-
0027759314
-
Bis(5-amidino-2-benzimidazolyl)methane and related amidines are potent, reversible inhibitors of mast cell tryptases
-
G.H. Caughey, W.W. Raymond, E. Bacci, R.J. Lombardy, and R.R. Tidwell Bis(5-amidino-2-benzimidazolyl)methane and related amidines are potent, reversible inhibitors of mast cell tryptases J. Pharmacol. Exp. Ther. 264 1993 676 682
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.264
, pp. 676-682
-
-
Caughey, G.H.1
Raymond, W.W.2
Bacci, E.3
Lombardy, R.J.4
Tidwell, R.R.5
-
20
-
-
0027415378
-
The human mast cell chymase gene (CMA1): Mapping to the cathepsin G/granzyme gene cluster and lineage-restricted expression
-
G.H. Caughey, T.H. Schaumberg, E.H. Zerweck, J.H. Butterfield, R.D. Hanson, G.A. Silverman, and T.J. Ley The human mast cell chymase gene (CMA1): mapping to the cathepsin G/granzyme gene cluster and lineage-restricted expression Genomics 15 1993 614 620
-
(1993)
Genomics
, vol.15
, pp. 614-620
-
-
Caughey, G.H.1
Schaumberg, T.H.2
Zerweck, E.H.3
Butterfield, J.H.4
Hanson, R.D.5
Silverman, G.A.6
Ley, T.J.7
-
21
-
-
0034659960
-
Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families
-
G.H. Caughey, W.W. Raymond, J.L. Blount, L.W.-T. Hau, M. Pallaoro, P.J. Wolters, and G.M. Verghese Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families J. Immunol. 164 2000 6566 6575
-
(2000)
J. Immunol.
, vol.164
, pp. 6566-6575
-
-
Caughey, G.H.1
Raymond, W.W.2
Blount, J.L.3
Hau, L.W.-T.4
Pallaoro, M.5
Wolters, P.J.6
Verghese, G.M.7
-
22
-
-
0034647653
-
Angiotensin II generation by mast cell alpha- and beta-chymases
-
G.H. Caughey, W.W. Raymond, and P.J. Wolters Angiotensin II generation by mast cell alpha- and beta-chymases Biochim. Biophys. Acta 1480 2000 245 257
-
(2000)
Biochim. Biophys. Acta
, vol.1480
, pp. 245-257
-
-
Caughey, G.H.1
Raymond, W.W.2
Wolters, P.J.3
-
23
-
-
0025835534
-
Structure, chromosomal assignment, and deduced amino acid sequence of a human gene for mast cell chymase
-
G.H. Caughey, E.H. Zerweck, and P. Vanderslice Structure, chromosomal assignment, and deduced amino acid sequence of a human gene for mast cell chymase J. Biol. Chem. 266 1991 12956 12963
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 12956-12963
-
-
Caughey, G.H.1
Zerweck, E.H.2
Vanderslice, P.3
-
24
-
-
33847342529
-
Role for protease activity in visceral pain in irritable bowel syndrome
-
N. Cenac, C.N. Andrews, M. Holzhausen, K. Chapman, G. Cottrell, P. Andrade-Gordon, M. Steinhoff, G. Barbara, P. Beck, N.W. Bunnett, K.A. Sharkey, J.G. Ferraz, E. Shaffer, and N. Vergnolle Role for protease activity in visceral pain in irritable bowel syndrome J. Clin. Invest. 117 2007 636 647
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 636-647
-
-
Cenac, N.1
Andrews, C.N.2
Holzhausen, M.3
Chapman, K.4
Cottrell, G.5
Andrade-Gordon, P.6
Steinhoff, M.7
Barbara, G.8
Beck, P.9
Bunnett, N.W.10
Sharkey, K.A.11
Ferraz, J.G.12
Shaffer, E.13
Vergnolle, N.14
-
25
-
-
84862892172
-
Lung mast cell density defines a subpopulation of patients with idiopathic pulmonary fibrosis
-
S.I. Cha, C.S. Chang, E.K. Kim, J.W. Lee, M.A. Matthay, J.A. Golden, B.M. Elicker, K. Jones, H.R. Collard, and P.J Wolters Lung mast cell density defines a subpopulation of patients with idiopathic pulmonary fibrosis Histopathology 61 2012 98 106
-
(2012)
Histopathology
, vol.61
, pp. 98-106
-
-
Cha, S.I.1
Chang, C.S.2
Kim, E.K.3
Lee, J.W.4
Matthay, M.A.5
Golden, J.A.6
Elicker, B.M.7
Jones, K.8
Collard, H.R.9
Wolters, P.J.10
-
26
-
-
33745455885
-
Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma
-
C.L. Chen, S.D. Wang, Z.Y. Zeng, K.J. Lin, S.T. Kao, T. Tani, C.K. Yu, and J.Y. Wang Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma J. Allergy Clin. Immunol. 118 2006 105 112
-
(2006)
J. Allergy Clin. Immunol.
, vol.118
, pp. 105-112
-
-
Chen, C.L.1
Wang, S.D.2
Zeng, Z.Y.3
Lin, K.J.4
Kao, S.T.5
Tani, T.6
Yu, C.K.7
Wang, J.Y.8
-
27
-
-
0036806825
-
Transgenic study of the function of chymase in heart remodeling
-
L.Y. Chen, P. Li, Q. He, L.Q. Jiang, C.J. Cui, L. Xu, and L.S. Liu Transgenic study of the function of chymase in heart remodeling J. Hypertens. 20 2002 2047 2055
-
(2002)
J. Hypertens.
, vol.20
, pp. 2047-2055
-
-
Chen, L.Y.1
Li, P.2
He, Q.3
Jiang, L.Q.4
Cui, C.J.5
Xu, L.6
Liu, L.S.7
-
28
-
-
0028820753
-
Tryptase inhibitors block allergen-induced airway and inflammatory responses in allergic sheep
-
J.M. Clark, W.M. Abraham, C.E. Fishman, R. Forteza, A. Ahmed, A. Cortes, R.L. Warne, W.R. Moore, and R.D. Tanaka Tryptase inhibitors block allergen-induced airway and inflammatory responses in allergic sheep Am. J. Respr. Crit. Care Med. 152 1995 2076 2083
-
(1995)
Am. J. Respr. Crit. Care Med.
, vol.152
, pp. 2076-2083
-
-
Clark, J.M.1
Abraham, W.M.2
Fishman, C.E.3
Forteza, R.4
Ahmed, A.5
Cortes, A.6
Warne, R.L.7
Moore, W.R.8
Tanaka, R.D.9
-
29
-
-
1842414265
-
Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2
-
C.U. Corvera, O. Dery, K. McConalogue, S.K. Bohm, L.M. Khitin, G.H. Caughey, D.G. Payan, and N.W. Bunnett Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2 J. Clin. Invest. 100 1997 1383 1393
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 1383-1393
-
-
Corvera, C.U.1
Dery, O.2
McConalogue, K.3
Bohm, S.K.4
Khitin, L.M.5
Caughey, G.H.6
Payan, D.G.7
Bunnett, N.W.8
-
30
-
-
40749086016
-
Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives
-
M.J. Costanzo, S.C. Yabut, H.C. Zhang, K.B. White, L. de Garavilla, Y. Wang, L.K. Minor, B.A. Tounge, A.N. Barnakov, F. Lewandowski, C. Milligan, J.C. Spurlino, W.M. Abraham, V. Boswell-Smith, C.P. Page, and B.E. Maryanoff Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives Bioorg. Med. Chem. Lett. 18 2114-2121 2008
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, Issue.2114-2121
-
-
Costanzo, M.J.1
Yabut, S.C.2
Zhang, H.C.3
White, K.B.4
De Garavilla, L.5
Wang, Y.6
Minor, L.K.7
Tounge, B.A.8
Barnakov, A.N.9
Lewandowski, F.10
Milligan, C.11
Spurlino, J.C.12
Abraham, W.M.13
Boswell-Smith, V.14
Page, C.P.15
Maryanoff, B.E.16
-
31
-
-
0033151608
-
Inflammatory mast cells upregulate angiogenesis during squamous epithelial carcinogenesis
-
L.M. Coussens, W.W. Raymond, G. Bergers, M. Laig-Webster, O. Behrendtsen, Z. Werb, G.H. Caughey, and D. Hanahan Inflammatory mast cells upregulate angiogenesis during squamous epithelial carcinogenesis Genes Dev. 13 1999 1382 1397
-
(1999)
Genes Dev.
, vol.13
, pp. 1382-1397
-
-
Coussens, L.M.1
Raymond, W.W.2
Bergers, G.3
Laig-Webster, M.4
Behrendtsen, O.5
Werb, Z.6
Caughey, G.H.7
Hanahan, D.8
-
32
-
-
0023920919
-
Ultrastructural analysis of human T and TC mast cells identified by immunoelectron microscopy
-
S.S. Craig, N.M. Schechter, and L.B. Schwartz Ultrastructural analysis of human T and TC mast cells identified by immunoelectron microscopy Lab. Invest. 58 1988 682 691
-
(1988)
Lab. Invest.
, vol.58
, pp. 682-691
-
-
Craig, S.S.1
Schechter, N.M.2
Schwartz, L.B.3
-
33
-
-
24044436201
-
A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: Molecular mechanisms and anti-inflammatory activity in vivo
-
L. De Garavilla, M.N. Greco, N. Sukumar, Z.W. Chen, A.O. Pineda, F.S. Mathews, E. Di Cera, E.C. Giardino, G.I. Wells, B.J. Haertlein, J.A. Kauffman, T.W. Corcoran, C.K. Derian, A.J. Eckardt, B.P. Damiano, P. Andrade-Gordon, and B.E. Maryanoff A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo J. Biol. Chem. 280 2005 18001 18007
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 18001-18007
-
-
De Garavilla, L.1
Greco, M.N.2
Sukumar, N.3
Chen, Z.W.4
Pineda, A.O.5
Mathews, F.S.6
Di Cera, E.7
Giardino, E.C.8
Wells, G.I.9
Haertlein, B.J.10
Kauffman, J.A.11
Corcoran, T.W.12
Derian, C.K.13
Eckardt, A.J.14
Damiano, B.P.15
Andrade-Gordon, P.16
Maryanoff, B.E.17
-
34
-
-
0036023644
-
Dissecting the role of chymase in angiotensin II formation and heart and blood vessel diseases
-
L.J. Dell'Italia, and A. Husain Dissecting the role of chymase in angiotensin II formation and heart and blood vessel diseases Curr. Opin. Cardiol. 17 2002 374 379
-
(2002)
Curr. Opin. Cardiol.
, vol.17
, pp. 374-379
-
-
Dell'Italia, L.J.1
Husain, A.2
-
35
-
-
33746932123
-
Human mast cell-derived gelatinase B (matrix metalloproteinase-9) is regulated by inflammatory cytokines: Role in cell migration
-
N. Di Girolamo, I. Indoh, N. Jackson, D. Wakefield, H.P. McNeil, W. Yan, C. Geczy, J.P. Arm, and N. Tedla Human mast cell-derived gelatinase B (matrix metalloproteinase-9) is regulated by inflammatory cytokines: role in cell migration J. Immunol. 177 2006 2638 2650
-
(2006)
J. Immunol.
, vol.177
, pp. 2638-2650
-
-
Di Girolamo, N.1
Indoh, I.2
Jackson, N.3
Wakefield, D.4
McNeil, H.P.5
Yan, W.6
Geczy, C.7
Arm, J.P.8
Tedla, N.9
-
36
-
-
84893344124
-
Development of mast cells and importance of their tryptase and chymase serine proteases in inflammation and wound healing
-
J. Douaiher, J. Succar, L. Lancerotto, M.F. Gurish, D.P. Orgill, M.J. Hamilton, S.A. Krilis, and R.L. Stevens Development of mast cells and importance of their tryptase and chymase serine proteases in inflammation and wound healing Adv. Immunol. 122 2014 211 252
-
(2014)
Adv. Immunol.
, vol.122
, pp. 211-252
-
-
Douaiher, J.1
Succar, J.2
Lancerotto, L.3
Gurish, M.F.4
Orgill, D.P.5
Hamilton, M.J.6
Krilis, S.A.7
Stevens, R.L.8
-
37
-
-
77951672627
-
Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma
-
R.H. Dougherty, S.S. Sidhu, K. Raman, M. Solon, O.D. Solberg, G.H. Caughey, P.G. Woodruff, and J.V. Fahy Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma J. Allergy Clin. Immunol. 125 2010 1046 1053
-
(2010)
J. Allergy Clin. Immunol.
, vol.125
, pp. 1046-1053
-
-
Dougherty, R.H.1
Sidhu, S.S.2
Raman, K.3
Solon, M.4
Solberg, O.D.5
Caughey, G.H.6
Woodruff, P.G.7
Fahy, J.V.8
-
38
-
-
33645305985
-
Effects of a reversible beta-tryptase and trypsin inhibitor (RWJ-58643) on nasal allergic responses
-
E.M. Erin, B.R. Leaker, A. Zacharasiewicz, L.A. Higgins, G.C. Nicholson, M.J. Boyce, P. de Boer, R.C. Jones, S.R. Durham, P.J. Barnes, and T.T. Hansel Effects of a reversible beta-tryptase and trypsin inhibitor (RWJ-58643) on nasal allergic responses Clin. Exp. Allergy 36 2006 458 464
-
(2006)
Clin. Exp. Allergy
, vol.36
, pp. 458-464
-
-
Erin, E.M.1
Leaker, B.R.2
Zacharasiewicz, A.3
Higgins, L.A.4
Nicholson, G.C.5
Boyce, M.J.6
De Boer, P.7
Jones, R.C.8
Durham, S.R.9
Barnes, P.J.10
Hansel, T.T.11
-
39
-
-
0037330931
-
Formation of active monomers from tetrameric human beta-tryptase
-
I. Fajardo, and G. Pejler Formation of active monomers from tetrameric human beta-tryptase Biochem. J. 369 2003 603 610
-
(2003)
Biochem. J.
, vol.369
, pp. 603-610
-
-
Fajardo, I.1
Pejler, G.2
-
40
-
-
0030845183
-
Dog mast cell a-chymase activates progelatinase B by cleaving the Phe88-Phe89 and Phe91-Glu92 bonds of the catalytic domain
-
K.C. Fang, W.W. Raymond, J.L. Blount, and G.H. Caughey Dog mast cell a-chymase activates progelatinase B by cleaving the Phe88-Phe89 and Phe91-Glu92 bonds of the catalytic domain J. Biol. Chem. 272 1997 25628 25635
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25628-25635
-
-
Fang, K.C.1
Raymond, W.W.2
Blount, J.L.3
Caughey, G.H.4
-
41
-
-
0029995317
-
Dog mastocytoma cells secrete a 92-kD gelatinase activated extracellularly by mast cell chymase
-
K.C. Fang, W.W. Raymond, S.C. Lazarus, and G.H. Caughey Dog mastocytoma cells secrete a 92-kD gelatinase activated extracellularly by mast cell chymase J. Clin. Invest. 97 1996 1589 1596
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 1589-1596
-
-
Fang, K.C.1
Raymond, W.W.2
Lazarus, S.C.3
Caughey, G.H.4
-
42
-
-
0033136337
-
Mast cell expression of gelatinases A and B is regulated by kit ligand and TGF-beta
-
K.C. Fang, P.J. Wolters, M. Steinhoff, A. Bidgol, J.L. Blount, and G.H. Caughey Mast cell expression of gelatinases A and B is regulated by kit ligand and TGF-beta J. Immunol. 162 1999 5528 5535
-
(1999)
J. Immunol.
, vol.162
, pp. 5528-5535
-
-
Fang, K.C.1
Wolters, P.J.2
Steinhoff, M.3
Bidgol, A.4
Blount, J.L.5
Caughey, G.H.6
-
43
-
-
21744448178
-
Loss of histochemical identity in mast cells lacking carboxypeptidase A
-
T.B. Feyerabend, H. Hausser, A. Tietz, C. Blum, L. Hellman, A.H. Straus, H.K. Takahashi, E.S. Morgan, A.M. Dvorak, H.J. Fehling, and H.R. Rodewald Loss of histochemical identity in mast cells lacking carboxypeptidase A Mol. Cell. Biol. 25 2005 6199 6210
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 6199-6210
-
-
Feyerabend, T.B.1
Hausser, H.2
Tietz, A.3
Blum, C.4
Hellman, L.5
Straus, A.H.6
Takahashi, H.K.7
Morgan, E.S.8
Dvorak, A.M.9
Fehling, H.J.10
Rodewald, H.R.11
-
44
-
-
81955164074
-
Cre-mediated cell ablation contests mast cell contribution in models of antibody- and T cell-mediated autoimmunity
-
T.B. Feyerabend, A. Weiser, A. Tietz, M. Stassen, N. Harris, M. Kopf, P. Radermacher, P. Moller, C. Benoist, D. Mathis, H.J. Fehling, and H.R. Rodewald Cre-mediated cell ablation contests mast cell contribution in models of antibody- and T cell-mediated autoimmunity Immunity 35 2011 832 844
-
(2011)
Immunity
, vol.35
, pp. 832-844
-
-
Feyerabend, T.B.1
Weiser, A.2
Tietz, A.3
Stassen, M.4
Harris, N.5
Kopf, M.6
Radermacher, P.7
Moller, P.8
Benoist, C.9
Mathis, D.10
Fehling, H.J.11
Rodewald, H.R.12
-
45
-
-
4143123236
-
Human beta-tryptase: Detection and characterization of the active monomer and prevention of tetramer reconstitution by protease inhibitors
-
Y. Fukuoka, and L.B. Schwartz Human beta-tryptase: detection and characterization of the active monomer and prevention of tetramer reconstitution by protease inhibitors Biochemistry 43 2004 10757 10764
-
(2004)
Biochemistry
, vol.43
, pp. 10757-10764
-
-
Fukuoka, Y.1
Schwartz, L.B.2
-
46
-
-
37249007305
-
Chymase activates promatrix metalloproteinase-9 in human abdominal aortic aneurysm
-
K. Furubayashi, S. Takai, D. Jin, M. Miyazaki, T. Katsumata, S. Inagaki, M. Kimura, K. Tanaka, M. Nishimoto, and H. Fukumoto Chymase activates promatrix metalloproteinase-9 in human abdominal aortic aneurysm Clin. Chim. Acta 388 2008 214 216
-
(2008)
Clin. Chim. Acta
, vol.388
, pp. 214-216
-
-
Furubayashi, K.1
Takai, S.2
Jin, D.3
Miyazaki, M.4
Katsumata, T.5
Inagaki, S.6
Kimura, M.7
Tanaka, K.8
Nishimoto, M.9
Fukumoto, H.10
-
47
-
-
33746267113
-
Rapid lineage-specific diversification of the mast cell chymase locus during mammalian evolution
-
M. Gallwitz, and L. Hellman Rapid lineage-specific diversification of the mast cell chymase locus during mammalian evolution Immunogenetics 58 2006 641 654
-
(2006)
Immunogenetics
, vol.58
, pp. 641-654
-
-
Gallwitz, M.1
Hellman, L.2
-
48
-
-
33746218574
-
Expansion of the mast cell chymase locus over the past 200 million years of mammalian evolution
-
M. Gallwitz, J.M. Reimer, and L. Hellman Expansion of the mast cell chymase locus over the past 200 million years of mammalian evolution Immunogenetics 58 2006 655 669
-
(2006)
Immunogenetics
, vol.58
, pp. 655-669
-
-
Gallwitz, M.1
Reimer, J.M.2
Hellman, L.3
-
49
-
-
0029787629
-
Fate of two mast cell tryptases in V3 mastocytosis and normal BALB/c mice undergoing passive systemic anaphylaxis: Prolonged retention of exocytosed mMCP-6 in connective tissues, and rapid accumulation of enzymatically active mMCP-7 in the blood
-
N. Ghildyal, D.S. Friend, R.L. Stevens, K.F. Austen, C. Huang, J.F. Penrose, A. Sali, and M.F. Gurish Fate of two mast cell tryptases in V3 mastocytosis and normal BALB/c mice undergoing passive systemic anaphylaxis: prolonged retention of exocytosed mMCP-6 in connective tissues, and rapid accumulation of enzymatically active mMCP-7 in the blood J. Exp. Med. 184 1996 1061 1073
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1061-1073
-
-
Ghildyal, N.1
Friend, D.S.2
Stevens, R.L.3
Austen, K.F.4
Huang, C.5
Penrose, J.F.6
Sali, A.7
Gurish, M.F.8
-
50
-
-
0026518944
-
Protease composition of exocytosed human skin mast cell protease-proteoglycan complexes: Tryptase resides in a complex distinct from chymase and carboxypeptidase
-
S.M. Goldstein, J. Leong, L.B. Schwartz, and D. Cooke Protease composition of exocytosed human skin mast cell protease-proteoglycan complexes: tryptase resides in a complex distinct from chymase and carboxypeptidase J. Immunol. 148 1992 2475 2482
-
(1992)
J. Immunol.
, vol.148
, pp. 2475-2482
-
-
Goldstein, S.M.1
Leong, J.2
Schwartz, L.B.3
Cooke, D.4
-
51
-
-
84885111507
-
Distorted secretory granule composition in mast cells with multiple protease deficiency
-
M. Grujic, G. Calounova, I. Eriksson, T. Feyerabend, H.R. Rodewald, E. Tchougounova, L. Kjellen, and G. Pejler Distorted secretory granule composition in mast cells with multiple protease deficiency J. Immunol. 191 2013 3931 3938
-
(2013)
J. Immunol.
, vol.191
, pp. 3931-3938
-
-
Grujic, M.1
Calounova, G.2
Eriksson, I.3
Feyerabend, T.4
Rodewald, H.R.5
Tchougounova, E.6
Kjellen, L.7
Pejler, G.8
-
52
-
-
0027277113
-
A closely linked complex of mouse mast cell-specific chymase genes on chromosome 14
-
M.F. Gurish, J.H. Nadeau, K.R. Johnson, H.P. McNeil, K.M. Grattan, K.F. Austen, and R.L. Stevens A closely linked complex of mouse mast cell-specific chymase genes on chromosome 14 J. Biol. Chem. 268 1993 11372 11379
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 11372-11379
-
-
Gurish, M.F.1
Nadeau, J.H.2
Johnson, K.R.3
McNeil, H.P.4
Grattan, K.M.5
Austen, K.F.6
Stevens, R.L.7
-
53
-
-
84855720149
-
Cathepsin G and neutrophil elastase play critical and nonredundant roles in lung-protective immunity against Streptococcus pneumoniae in mice
-
I. Hahn, A. Klaus, A.K. Janze, K. Steinwede, N. Ding, J. Bohling, C. Brumshagen, H. Serrano, F. Gauthier, J.C. Paton, T. Welte, and U.A. Maus Cathepsin G and neutrophil elastase play critical and nonredundant roles in lung-protective immunity against Streptococcus pneumoniae in mice Infect. Immun. 79 2011 4893 4901
-
(2011)
Infect. Immun.
, vol.79
, pp. 4893-4901
-
-
Hahn, I.1
Klaus, A.2
Janze, A.K.3
Steinwede, K.4
Ding, N.5
Bohling, J.6
Brumshagen, C.7
Serrano, H.8
Gauthier, F.9
Paton, J.C.10
Welte, T.11
Maus, U.A.12
-
54
-
-
9644262525
-
Structural requirements and mechanism for heparin-dependent activation and tetramerization of human betaI- and betaII-tryptase
-
J. Hallgren, S. Lindahl, and G. Pejler Structural requirements and mechanism for heparin-dependent activation and tetramerization of human betaI- and betaII-tryptase J. Mol. Biol. 345 2005 129 139
-
(2005)
J. Mol. Biol.
, vol.345
, pp. 129-139
-
-
Hallgren, J.1
Lindahl, S.2
Pejler, G.3
-
55
-
-
33646262595
-
Biology of mast cell tryptase. An inflammatory mediator
-
J. Hallgren, and G. Pejler Biology of mast cell tryptase. An inflammatory mediator FEBS J. 273 2006 1871 1895
-
(2006)
FEBS J.
, vol.273
, pp. 1871-1895
-
-
Hallgren, J.1
Pejler, G.2
-
56
-
-
78651077289
-
Essential role for mast cell tryptase in acute experimental colitis
-
M.J. Hamilton, M.J. Sinnamon, G.D. Lyng, J.N. Glickman, X. Wang, W. Xing, S.A. Krilis, R.S. Blumberg, R. Adachi, D.M. Lee, and R.L. Stevens Essential role for mast cell tryptase in acute experimental colitis Proc. Natl. Acad. Sci. USA 108 2010 290 295
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 290-295
-
-
Hamilton, M.J.1
Sinnamon, M.J.2
Lyng, G.D.3
Glickman, J.N.4
Wang, X.5
Xing, W.6
Krilis, S.A.7
Blumberg, R.S.8
Adachi, R.9
Lee, D.M.10
Stevens, R.L.11
-
57
-
-
84903516573
-
Importance of mast cell Prss31/Transmembrane Tryptase/Tryptase-gamma in lung function and experimental chronic obstructive pulmonary disease and colitis
-
P.M. Hansbro, M.J. Hamilton, M. Fricker, S.L. Gellatly, A.G. Jarnicki, D. Zheng, S.M. Frei, G.W. Wong, S. Hamadi, S. Zhou, P.M. Foster, S.A. Krilis, and R.L. Stevens Importance of mast cell Prss31/Transmembrane Tryptase/Tryptase-gamma in lung function and experimental chronic obstructive pulmonary disease and colitis J. Biol. Chem. 289 26 2014 18214 18227
-
(2014)
J. Biol. Chem.
, vol.289
, Issue.26
, pp. 18214-18227
-
-
Hansbro, P.M.1
Hamilton, M.J.2
Fricker, M.3
Gellatly, S.L.4
Jarnicki, A.G.5
Zheng, D.6
Frei, S.M.7
Wong, G.W.8
Hamadi, S.9
Zhou, S.10
Foster, P.M.11
Krilis, S.A.12
Stevens, R.L.13
-
58
-
-
84906945203
-
Molecular targets on mast cells and basophils for novel therapies
-
I.T. Harvima, F. Levi-Schaffer, P. Draber, S. Friedman, I. Polakovicova, B.F. Gibbs, U. Blank, G. Nilsson, and M. Maurer Molecular targets on mast cells and basophils for novel therapies J. Allergy Clin. Immunol. 134 2014 530 544
-
(2014)
J. Allergy Clin. Immunol.
, vol.134
, pp. 530-544
-
-
Harvima, I.T.1
Levi-Schaffer, F.2
Draber, P.3
Friedman, S.4
Polakovicova, I.5
Gibbs, B.F.6
Blank, U.7
Nilsson, G.8
Maurer, M.9
-
59
-
-
84890360051
-
Granule proteases of hematopoietic cells, a family of versatile inflammatory mediators - An update on their cleavage specificity, in vivo substrates, and evolution
-
L. Hellman, and M. Thorpe Granule proteases of hematopoietic cells, a family of versatile inflammatory mediators - an update on their cleavage specificity, in vivo substrates, and evolution Biol. Chem. 395 2014 15 49
-
(2014)
Biol. Chem.
, vol.395
, pp. 15-49
-
-
Hellman, L.1
Thorpe, M.2
-
60
-
-
0024313344
-
Genomic organization and chromosomal localization of the human cathepsin G gene
-
P.A. Hohn, N.C. Popescu, R.D. Hanson, G. Salvesen, and T.J. Ley Genomic organization and chromosomal localization of the human cathepsin G gene J. Biol. Chem. 264 1989 13412 13419
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 13412-13419
-
-
Hohn, P.A.1
Popescu, N.C.2
Hanson, R.D.3
Salvesen, G.4
Ley, T.J.5
-
61
-
-
0025826290
-
Cloning and structural analysis of MMCP-1, MMCP-4 and MMCP-5, three mouse mast cell-specific serine proteases
-
R. Huang, T. Blom, and L. Hellman Cloning and structural analysis of MMCP-1, MMCP-4 and MMCP-5, three mouse mast cell-specific serine proteases Eur. J. Immunol. 21 1991 1611 1621
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 1611-1621
-
-
Huang, R.1
Blom, T.2
Hellman, L.3
-
62
-
-
0033584326
-
Heparin is essential for the storage of specific granule proteases in mast cells [see comments]
-
D.E. Humphries, G.W. Wong, D.S. Friend, M.F. Gurish, W.T. Qiu, C. Huang, A.H. Sharpe, and R.L. Stevens Heparin is essential for the storage of specific granule proteases in mast cells [see comments] Nature 400 1999 769 772
-
(1999)
Nature
, vol.400
, pp. 769-772
-
-
Humphries, D.E.1
Wong, G.W.2
Friend, D.S.3
Gurish, M.F.4
Qiu, W.T.5
Huang, C.6
Sharpe, A.H.7
Stevens, R.L.8
-
63
-
-
0030028575
-
Natural disruption of the mouse mast cell protease 7 gene in the C57BL/6 mouse
-
J.E. Hunt, R.L. Stevens, K.F. Austen, J. Zhang, Z.N. Xia, and N. Ghildyal Natural disruption of the mouse mast cell protease 7 gene in the C57BL/6 mouse J. Biol. Chem. 271 1996 2851 2855
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2851-2855
-
-
Hunt, J.E.1
Stevens, R.L.2
Austen, K.F.3
Zhang, J.4
Xia, Z.N.5
Ghildyal, N.6
-
64
-
-
67349109176
-
Effects of chymase inhibitor on angiotensin II-induced abdominal aortic aneurysm development in apolipoprotein E-deficient mice
-
N. Inoue, M. Muramatsu, D. Jin, S. Takai, T. Hayashi, H. Katayama, Y. Kitaura, H. Tamai, and M. Miyazaki Effects of chymase inhibitor on angiotensin II-induced abdominal aortic aneurysm development in apolipoprotein E-deficient mice Atherosclerosis 204 2009 359 364
-
(2009)
Atherosclerosis
, vol.204
, pp. 359-364
-
-
Inoue, N.1
Muramatsu, M.2
Jin, D.3
Takai, S.4
Hayashi, T.5
Katayama, H.6
Kitaura, Y.7
Tamai, H.8
Miyazaki, M.9
-
65
-
-
0024474186
-
Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies
-
A.M. Irani, T.R. Bradford, C.L. Kepley, N.M. Schechter, and L.B. Schwartz Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies J. Histochem. Cytochem. 37 1989 1509 1515
-
(1989)
J. Histochem. Cytochem.
, vol.37
, pp. 1509-1515
-
-
Irani, A.M.1
Bradford, T.R.2
Kepley, C.L.3
Schechter, N.M.4
Schwartz, L.B.5
-
66
-
-
0025991033
-
Human mast cell carboxypeptidase: Selective localization to MCTC cells
-
A.M. Irani, S.M. Goldstein, B.U. Wintroub, T. Bradford, and L.B. Schwartz Human mast cell carboxypeptidase: selective localization to MCTC cells J. Immunol. 147 1991 247 253
-
(1991)
J. Immunol.
, vol.147
, pp. 247-253
-
-
Irani, A.M.1
Goldstein, S.M.2
Wintroub, B.U.3
Bradford, T.4
Schwartz, L.B.5
-
67
-
-
33745726787
-
Anti-tryptase treatment using nafamostat mesilate has a therapeutic effect on experimental colitis
-
Y. Isozaki, N. Yoshida, M. Kuroda, O. Handa, T. Takagi, S. Kokura, H. Ichikawa, Y. Naito, T. Okanoue, and T. Yoshikawa Anti-tryptase treatment using nafamostat mesilate has a therapeutic effect on experimental colitis Scand. J. Gastroenterol. 41 2006 944 953
-
(2006)
Scand. J. Gastroenterol.
, vol.41
, pp. 944-953
-
-
Isozaki, Y.1
Yoshida, N.2
Kuroda, M.3
Handa, O.4
Takagi, T.5
Kokura, S.6
Ichikawa, H.7
Naito, Y.8
Okanoue, T.9
Yoshikawa, T.10
-
68
-
-
57749207972
-
Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation
-
N.E. Jackson, H.W. Wang, K.J. Bryant, H.P. McNeil, A. Husain, K. Liu, N. Tedla, P.S. Thomas, G.C. King, A. Hettiaratchi, J. Cairns, and J.E. Hunt Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation J. Biol. Chem. 283 2008 34178 34187
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 34178-34187
-
-
Jackson, N.E.1
Wang, H.W.2
Bryant, K.J.3
McNeil, H.P.4
Husain, A.5
Liu, K.6
Tedla, N.7
Thomas, P.S.8
King, G.C.9
Hettiaratchi, A.10
Cairns, J.11
Hunt, J.E.12
-
69
-
-
24744432512
-
Mast cell tryptase controls paracellular permeability of the intestine. Role of protease-activated receptor 2 and beta-arrestins
-
C. Jacob, P.C. Yang, D. Darmoul, S. Amadesi, T. Saito, G.S. Cottrell, A.M. Coelho, P. Singh, E.F. Grady, M. Perdue, and N.W. Bunnett Mast cell tryptase controls paracellular permeability of the intestine. Role of protease-activated receptor 2 and beta-arrestins J. Biol. Chem. 280 2005 31936 31948
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 31936-31948
-
-
Jacob, C.1
Yang, P.C.2
Darmoul, D.3
Amadesi, S.4
Saito, T.5
Cottrell, G.S.6
Coelho, A.M.7
Singh, P.8
Grady, E.F.9
Perdue, M.10
Bunnett, N.W.11
-
70
-
-
0030844701
-
Quantitative analysis of tryptase- and chymase-containing mast cells in atopic dermatitis and nummular eczema
-
A. Järvikallio, A. Naukkarinen, I.T. Harvima, M.L. Aalto, and M. Horsmanheimo Quantitative analysis of tryptase- and chymase-containing mast cells in atopic dermatitis and nummular eczema Br. J. Dermatol. 136 1997 871 877
-
(1997)
Br. J. Dermatol.
, vol.136
, pp. 871-877
-
-
Järvikallio, A.1
Naukkarinen, A.2
Harvima, I.T.3
Aalto, M.L.4
Horsmanheimo, M.5
-
71
-
-
0034931806
-
Possible roles of cardiac chymase after myocardial infarction in hamster hearts
-
D. Jin, S. Takai, M. Yamada, M. Sakaguchi, Y. Yao, and M. Miyazaki Possible roles of cardiac chymase after myocardial infarction in hamster hearts Jpn. J. Pharmacol. 86 2001 203 214
-
(2001)
Jpn. J. Pharmacol.
, vol.86
, pp. 203-214
-
-
Jin, D.1
Takai, S.2
Yamada, M.3
Sakaguchi, M.4
Yao, Y.5
Miyazaki, M.6
-
72
-
-
3042795013
-
Expression of alpha-tryptase and beta-tryptase by human basophils
-
S. Jogie-Brahim, H.K. Min, Y. Fukuoka, H.Z. Xia, and L.B. Schwartz Expression of alpha-tryptase and beta-tryptase by human basophils J. Allergy Clin. Immunol. 113 2004 1086 1092
-
(2004)
J. Allergy Clin. Immunol.
, vol.113
, pp. 1086-1092
-
-
Jogie-Brahim, S.1
Min, H.K.2
Fukuoka, Y.3
Xia, H.Z.4
Schwartz, L.B.5
-
73
-
-
0035912706
-
Conditional and targeted overexpression of vascular chymase causes hypertension in transgenic mice
-
H. Ju, R. Gros, X. You, S. Tsang, M. Husain, and M. Rabinovitch Conditional and targeted overexpression of vascular chymase causes hypertension in transgenic mice Proc. Natl. Acad. Sci. USA 98 2001 7469 7474
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 7469-7474
-
-
Ju, H.1
Gros, R.2
You, X.3
Tsang, S.4
Husain, M.5
Rabinovitch, M.6
-
74
-
-
71749106553
-
Structural characterization of mouse neutrophil serine proteases and identification of their substrate specificities: Relevance to mouse models of human inflammatory diseases
-
T. Kalupov, M. Brillard-Bourdet, S. Dade, H. Serrano, J. Wartelle, N. Guyot, L. Juliano, T. Moreau, A. Belaaouaj, and F. Gauthier Structural characterization of mouse neutrophil serine proteases and identification of their substrate specificities: relevance to mouse models of human inflammatory diseases J. Biol. Chem. 284 2009 34084 34091
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 34084-34091
-
-
Kalupov, T.1
Brillard-Bourdet, M.2
Dade, S.3
Serrano, H.4
Wartelle, J.5
Guyot, N.6
Juliano, L.7
Moreau, T.8
Belaaouaj, A.9
Gauthier, F.10
-
75
-
-
0141960165
-
Extended substrate specificity of rat mast cell protease 5, a rodent alpha-chymase with elastase-like primary specificity
-
U. Karlson, G. Pejler, B. Tomasini-Johansson, and L. Hellman Extended substrate specificity of rat mast cell protease 5, a rodent alpha-chymase with elastase-like primary specificity J. Biol. Chem. 278 2003 39625 39631
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 39625-39631
-
-
Karlson, U.1
Pejler, G.2
Tomasini-Johansson, B.3
Hellman, L.4
-
76
-
-
38049110578
-
Structural basis for elastolytic substrate specificity in rodent alpha-chymases
-
J. Kervinen, M. Abad, C. Crysler, M. Kolpak, A.D. Mahan, J.A. Masucci, S. Bayoumy, M.D. Cummings, X. Yao, M. Olson, L. de Garavilla, L. Kuo, I. Deckman, and J. Spurlino Structural basis for elastolytic substrate specificity in rodent alpha-chymases J. Biol. Chem. 283 2008 427 436
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 427-436
-
-
Kervinen, J.1
Abad, M.2
Crysler, C.3
Kolpak, M.4
Mahan, A.D.5
Masucci, J.A.6
Bayoumy, S.7
Cummings, M.D.8
Yao, X.9
Olson, M.10
De Garavilla, L.11
Kuo, L.12
Deckman, I.13
Spurlino, J.14
-
77
-
-
77955661713
-
Potency variation of small-molecule chymase inhibitors across species
-
J. Kervinen, C. Crysler, S. Bayoumy, M.C. Abad, J. Spurlino, I. Deckman, M.N. Greco, B.E. Maryanoff, and L. de Garavilla Potency variation of small-molecule chymase inhibitors across species Biochem. Pharmacol. 80 2010 1033 1041
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 1033-1041
-
-
Kervinen, J.1
Crysler, C.2
Bayoumy, S.3
Abad, M.C.4
Spurlino, J.5
Deckman, I.6
Greco, M.N.7
Maryanoff, B.E.8
De Garavilla, L.9
-
78
-
-
0025937755
-
Multiple determinants for the high substrate specificity of an angiotensin II-forming chymase from the human heart
-
A. Kinoshita, H. Urata, F.M. Bumpus, and A. Husain Multiple determinants for the high substrate specificity of an angiotensin II-forming chymase from the human heart J. Biol. Chem. 266 1991 19192 19197
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 19192-19197
-
-
Kinoshita, A.1
Urata, H.2
Bumpus, F.M.3
Husain, A.4
-
79
-
-
0034684681
-
Delayed expulsion of the nematode Trichinella spiralis in mice lacking the mucosal mast cell-specific granule chymase, mouse mast cell protease-1
-
P.A. Knight, S.H. Wright, C.E. Lawrence, Y.Y. Paterson, and H.R. Miller Delayed expulsion of the nematode Trichinella spiralis in mice lacking the mucosal mast cell-specific granule chymase, mouse mast cell protease-1 J. Exp. Med. 192 2000 1849 1856
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1849-1856
-
-
Knight, P.A.1
Wright, S.H.2
Lawrence, C.E.3
Paterson, Y.Y.4
Miller, H.R.5
-
80
-
-
10744227689
-
Human chymase expression in a mice induces mild hypertension with left ventricular hypertrophy
-
T. Koga, H. Urata, Y. Inoue, T. Hoshino, T. Okamoto, A. Matsunaga, M. Suzuki, J. Miyazaki, M. Ideishi, K. Arakawa, and K. Saku Human chymase expression in a mice induces mild hypertension with left ventricular hypertrophy Hypertens. Res. 26 2003 759 768
-
(2003)
Hypertens. Res.
, vol.26
, pp. 759-768
-
-
Koga, T.1
Urata, H.2
Inoue, Y.3
Hoshino, T.4
Okamoto, T.5
Matsunaga, A.6
Suzuki, M.7
Miyazaki, J.8
Ideishi, M.9
Arakawa, K.10
Saku, K.11
-
81
-
-
85026336613
-
Histological characterization of mast cell chymase in patients with pulmonary hypertension and chronic obstructive pulmonary disease
-
D. Kosanovic, B.K. Dahal, D.M. Peters, M. Seimetz, M. Wygrecka, K. Hoffmann, J. Antel, I. Reiss, H.A. Ghofrani, N. Weissmann, F. Grimminger, W. Seeger, and R.T. Schermuly Histological characterization of mast cell chymase in patients with pulmonary hypertension and chronic obstructive pulmonary disease Pulm. Circ. 4 2014 128 136
-
(2014)
Pulm. Circ.
, vol.4
, pp. 128-136
-
-
Kosanovic, D.1
Dahal, B.K.2
Peters, D.M.3
Seimetz, M.4
Wygrecka, M.5
Hoffmann, K.6
Antel, J.7
Reiss, I.8
Ghofrani, H.A.9
Weissmann, N.10
Grimminger, F.11
Seeger, W.12
Schermuly, R.T.13
-
82
-
-
0035013541
-
Inhibition of mast cell tryptase by inhaled APC 366 attenuates allergen-induced late-phase airway obstruction in asthma
-
M.T. Krishna, A. Chauhan, L. Little, K. Sampson, R. Hawksworth, T. Mant, R. Djukanovic, T. Lee, and S. Holgate Inhibition of mast cell tryptase by inhaled APC 366 attenuates allergen-induced late-phase airway obstruction in asthma J. Allergy Clin. Immunol. 107 2001 1039 1045
-
(2001)
J. Allergy Clin. Immunol.
, vol.107
, pp. 1039-1045
-
-
Krishna, M.T.1
Chauhan, A.2
Little, L.3
Sampson, K.4
Hawksworth, R.5
Mant, T.6
Djukanovic, R.7
Lee, T.8
Holgate, S.9
-
83
-
-
0036446159
-
Rodent alpha-chymases are elastase-like proteases
-
Y. Kunori, M. Koizumi, T. Masegi, H. Kasai, H. Kawabata, Y. Yamazaki, and A. Fukamizu Rodent alpha-chymases are elastase-like proteases Eur. J. Biochem. 269 2002 5921 5930
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 5921-5930
-
-
Kunori, Y.1
Koizumi, M.2
Masegi, T.3
Kasai, H.4
Kawabata, H.5
Yamazaki, Y.6
Fukamizu, A.7
-
84
-
-
80051931143
-
Processing of human protryptase in mast cells involves cathepsins L, B, and C
-
Q.T. Le, G. Gomez, W. Zhao, J. Hu, H.Z. Xia, Y. Fukuoka, N. Katunuma, and L.B. Schwartz Processing of human protryptase in mast cells involves cathepsins L, B, and C J. Immunol. 187 2011 1912 1918
-
(2011)
J. Immunol.
, vol.187
, pp. 1912-1918
-
-
Le, Q.T.1
Gomez, G.2
Zhao, W.3
Hu, J.4
Xia, H.Z.5
Fukuoka, Y.6
Katunuma, N.7
Schwartz, L.B.8
-
85
-
-
79959564979
-
Promiscuous processing of human alpha/beta-protryptases by cathepsins L, B, and C
-
Q.T. Le, H.K. Min, H.Z. Xia, Y. Fukuoka, N. Katunuma, and L.B. Schwartz Promiscuous processing of human alpha/beta-protryptases by cathepsins L, B, and C J. Immunol. 186 2011 7136 7143
-
(2011)
J. Immunol.
, vol.186
, pp. 7136-7143
-
-
Le, Q.T.1
Min, H.K.2
Xia, H.Z.3
Fukuoka, Y.4
Katunuma, N.5
Schwartz, L.B.6
-
86
-
-
3242769190
-
Involvement of chymase-mediated angiotensin II generation in blood pressure regulation
-
M. Li, K. Liu, J. Michalicek, J.A. Angus, J.E. Hunt, L.J. Dell'Italia, M.P. Feneley, R.M. Graham, and A. Husain Involvement of chymase-mediated angiotensin II generation in blood pressure regulation J. Clin. Invest. 114 2004 112 120
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 112-120
-
-
Li, M.1
Liu, K.2
Michalicek, J.3
Angus, J.A.4
Hunt, J.E.5
Dell'Italia, L.J.6
Feneley, M.P.7
Graham, R.M.8
Husain, A.9
-
87
-
-
84255176446
-
Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice
-
J.N. Lilla, C.C. Chen, K. Mukai, M.J. Benbarak, C.B. Franco, J. Kalesnikoff, M. Yu, M. Tsai, A.M. Piliponsky, and S.J. Galli Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice Blood 118 2011 6930 6938
-
(2011)
Blood
, vol.118
, pp. 6930-6938
-
-
Lilla, J.N.1
Chen, C.C.2
Mukai, K.3
Benbarak, M.J.4
Franco, C.B.5
Kalesnikoff, J.6
Yu, M.7
Tsai, M.8
Piliponsky, A.M.9
Galli, S.J.10
-
88
-
-
84862505087
-
Murine but not human basophil undergoes cell-specific proteolysis of a major endoplasmic reticulum chaperone
-
B. Liu, M. Staron, and Z. Li Murine but not human basophil undergoes cell-specific proteolysis of a major endoplasmic reticulum chaperone PLoS One 7 2012 e39442
-
(2012)
PLoS One
, vol.7
-
-
Liu, B.1
Staron, M.2
Li, Z.3
-
89
-
-
3543030410
-
Cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin II
-
A. Lundequist, E. Tchougounova, M. Abrink, and G. Pejler Cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin II J. Biol. Chem. 279 2004 32339 32344
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 32339-32344
-
-
Lundequist, A.1
Tchougounova, E.2
Abrink, M.3
Pejler, G.4
-
90
-
-
0039649450
-
Secretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations
-
C. Lutzelschwab, G. Pejler, M. Aveskogh, and L. Hellman Secretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations J. Exp. Med. 185 1997 13 29
-
(1997)
J. Exp. Med.
, vol.185
, pp. 13-29
-
-
Lutzelschwab, C.1
Pejler, G.2
Aveskogh, M.3
Hellman, L.4
-
91
-
-
84899632659
-
Mendelian inheritance of elevated serum tryptase associated with atopy and connective tissue abnormalities
-
J.J. Lyons, G. Sun, K.D. Stone, C. Nelson, L. Wisch, M. O'Brien, N. Jones, A. Lindsley, H.D. Komarow, Y. Bai, L.M. Scott, D. Cantave, I. Maric, J.P. Abonia, M.E. Rothenberg, L.B. Schwartz, J.D. Milner, and T.M. Wilson Mendelian inheritance of elevated serum tryptase associated with atopy and connective tissue abnormalities J. Allergy Clin. Immunol. 133 2014 1471 1474
-
(2014)
J. Allergy Clin. Immunol.
, vol.133
, pp. 1471-1474
-
-
Lyons, J.J.1
Sun, G.2
Stone, K.D.3
Nelson, C.4
Wisch, L.5
O'Brien, M.6
Jones, N.7
Lindsley, A.8
Komarow, H.D.9
Bai, Y.10
Scott, L.M.11
Cantave, D.12
Maric, I.13
Abonia, J.P.14
Rothenberg, M.E.15
Schwartz, L.B.16
Milner, J.D.17
Wilson, T.M.18
-
92
-
-
1642337351
-
Mast cell dipeptidyl peptidase I mediates survival from sepsis
-
J. Mallen-St Clair, C.T. Pham, S.A. Villalta, G.H. Caughey, and P.J. Wolters Mast cell dipeptidyl peptidase I mediates survival from sepsis J. Clin. Invest. 113 2004 628 634
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 628-634
-
-
Mallen-St Clair, J.1
Pham, C.T.2
Villalta, S.A.3
Caughey, G.H.4
Wolters, P.J.5
-
93
-
-
9644269070
-
Mast cells promote homeostasis by limiting endothelin-1-induced toxicity
-
M. Maurer, J. Wedemeyer, M. Metz, A.M. Piliponsky, K. Weller, D. Chatterjea, D.E. Clouthier, M.M. Yanagisawa, M. Tsai, and S.J. Galli Mast cells promote homeostasis by limiting endothelin-1-induced toxicity Nature 432 2004 512 516
-
(2004)
Nature
, vol.432
, pp. 512-516
-
-
Maurer, M.1
Wedemeyer, J.2
Metz, M.3
Piliponsky, A.M.4
Weller, K.5
Chatterjea, D.6
Clouthier, D.E.7
Yanagisawa, M.M.8
Tsai, M.9
Galli, S.J.10
-
94
-
-
0027518670
-
Generation of active myeloid and lymphoid granule serine proteases requires processing by the granule thiol protease dipeptidyl peptidase I
-
M.J. McGuire, P.E. Lipsky, and D.L. Thiele Generation of active myeloid and lymphoid granule serine proteases requires processing by the granule thiol protease dipeptidyl peptidase I J. Biol. Chem. 268 1993 2458 2467
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 2458-2467
-
-
McGuire, M.J.1
Lipsky, P.E.2
Thiele, D.L.3
-
95
-
-
34547098830
-
Mast cell-restricted tryptases: Structure and function in inflammation and pathogen defense
-
H.P. McNeil, R. Adachi, and R.L. Stevens Mast cell-restricted tryptases: structure and function in inflammation and pathogen defense J. Biol. Chem. 282 2007 20785 20789
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 20785-20789
-
-
McNeil, H.P.1
Adachi, R.2
Stevens, R.L.3
-
96
-
-
0025789989
-
Molecular cloning of the mouse mast cell protease-5 gene. A novel secretory granule protease expressed early in the differentiation of serosal mast cells
-
H.P. McNeil, K.F. Austen, L.L. Somerville, M.F. Gurish, and R.L. Stevens Molecular cloning of the mouse mast cell protease-5 gene. A novel secretory granule protease expressed early in the differentiation of serosal mast cells J. Biol. Chem. 266 1991 20316 20322
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 20316-20322
-
-
McNeil, H.P.1
Austen, K.F.2
Somerville, L.L.3
Gurish, M.F.4
Stevens, R.L.5
-
97
-
-
49449109723
-
The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis
-
H.P. McNeil, K. Shin, I.K. Campbell, I.P. Wicks, R. Adachi, D.M. Lee, and R.L. Stevens The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis Arthritis Rheum. 58 2008 2338 2346
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 2338-2346
-
-
McNeil, H.P.1
Shin, K.2
Campbell, I.K.3
Wicks, I.P.4
Adachi, R.5
Lee, D.M.6
Stevens, R.L.7
-
98
-
-
33746642081
-
Mast cells can enhance resistance to snake and honeybee venoms
-
M. Metz, A.M. Piliponsky, C.C. Chen, V. Lammel, M. Abrink, G. Pejler, M. Tsai, and S.J. Galli Mast cells can enhance resistance to snake and honeybee venoms Science 313 2006 526 530
-
(2006)
Science
, vol.313
, pp. 526-530
-
-
Metz, M.1
Piliponsky, A.M.2
Chen, C.C.3
Lammel, V.4
Abrink, M.5
Pejler, G.6
Tsai, M.7
Galli, S.J.8
-
99
-
-
0025053169
-
Cloning and characterization of a second complementary cDNA for human tryptase
-
J.S. Miller, G. Moxley, and L.B. Schwartz Cloning and characterization of a second complementary cDNA for human tryptase J. Clin. Invest. 86 1990 864 870
-
(1990)
J. Clin. Invest.
, vol.86
, pp. 864-870
-
-
Miller, J.S.1
Moxley, G.2
Schwartz, L.B.3
-
100
-
-
0035116779
-
Human mouse mast cell protease 7-like tryptase genes are pseudogenes
-
H.K. Min, N. Kambe, and L.B. Schwartz Human mouse mast cell protease 7-like tryptase genes are pseudogenes J. Allergy Clin. Immunol. 107 2001 315 321
-
(2001)
J. Allergy Clin. Immunol.
, vol.107
, pp. 315-321
-
-
Min, H.K.1
Kambe, N.2
Schwartz, L.B.3
-
101
-
-
33750032795
-
Pathological roles of angiotensin II produced by mast cell chymase and the effects of chymase inhibition in animal models
-
M. Miyazaki, S. Takai, D. Jin, and M. Muramatsu Pathological roles of angiotensin II produced by mast cell chymase and the effects of chymase inhibition in animal models Pharmacol. Ther. 112 2006 668 676
-
(2006)
Pharmacol. Ther.
, vol.112
, pp. 668-676
-
-
Miyazaki, M.1
Takai, S.2
Jin, D.3
Muramatsu, M.4
-
102
-
-
0041694064
-
Nafamostat mesilate is an extremely potent inhibitor of human tryptase
-
S. Mori, Y. Itoh, R. Shinohata, T. Sendo, R. Oishi, and M. Nishibori Nafamostat mesilate is an extremely potent inhibitor of human tryptase J. Pharmacol. Sci. 92 2003 420 423
-
(2003)
J. Pharmacol. Sci.
, vol.92
, pp. 420-423
-
-
Mori, S.1
Itoh, Y.2
Shinohata, R.3
Sendo, T.4
Oishi, R.5
Nishibori, M.6
-
103
-
-
14844304303
-
Mast cell chymase in the ischemic kidney of severe unilateral renovascular hypertension
-
T. Morikawa, M. Imanishi, H. Suzuki, N. Okada, M. Okumura, Y. Konishi, K. Yoshioka, S. Takai, and M. Miyazaki Mast cell chymase in the ischemic kidney of severe unilateral renovascular hypertension Am. J. Kidney Dis. 45 2005 e45 50
-
(2005)
Am. J. Kidney Dis.
, vol.45
, pp. e45-e50
-
-
Morikawa, T.1
Imanishi, M.2
Suzuki, H.3
Okada, N.4
Okumura, M.5
Konishi, Y.6
Yoshioka, K.7
Takai, S.8
Miyazaki, M.9
-
104
-
-
0037193192
-
Lys40 but not Arg143 influences selectivity of angiotensin conversion by human alpha-chymase
-
D.J. Muilenburg, W.W. Raymond, P.J. Wolters, and G.H. Caughey Lys40 but not Arg143 influences selectivity of angiotensin conversion by human alpha-chymase Biochim. Biophys. Acta 1596 2002 346 356
-
(2002)
Biochim. Biophys. Acta
, vol.1596
, pp. 346-356
-
-
Muilenburg, D.J.1
Raymond, W.W.2
Wolters, P.J.3
Caughey, G.H.4
-
105
-
-
0035845676
-
Significance of chymase-dependent angiotensin II-forming pathway in the development of vascular proliferation
-
M. Nishimoto, S. Takai, S. Kim, D. Jin, A. Yuda, M. Sakaguchi, M. Yamada, Y. Sawada, K. Kondo, K. Asada, H. Iwao, S. Sasaki, and M. Miyazaki Significance of chymase-dependent angiotensin II-forming pathway in the development of vascular proliferation Circulation 104 2001 1274 1279
-
(2001)
Circulation
, vol.104
, pp. 1274-1279
-
-
Nishimoto, M.1
Takai, S.2
Kim, S.3
Jin, D.4
Yuda, A.5
Sakaguchi, M.6
Yamada, M.7
Sawada, Y.8
Kondo, K.9
Asada, K.10
Iwao, H.11
Sasaki, S.12
Miyazaki, M.13
-
106
-
-
0037083293
-
Tryptase inhibition blocks airway inflammation in a mouse asthma model
-
S.-W. Oh, C.I. Pae, D.-K. Lee, F. Jones, G.K.S. Chiang, H.-O. Kim, S.-H. Moon, B. Cao, C. Ogbu, K.-W. Jeong, G. Kozu, H. Nakanishi, M. Kahn, E.Y. Chi, and W.R. Henderson Jr. Tryptase inhibition blocks airway inflammation in a mouse asthma model J. Immunol. 168 2002 1992 2000
-
(2002)
J. Immunol.
, vol.168
, pp. 1992-2000
-
-
Oh, S.-W.1
Pae, C.I.2
Lee, D.-K.3
Jones, F.4
Chiang, G.K.S.5
Kim, H.-O.6
Moon, S.-H.7
Cao, B.8
Ogbu, C.9
Jeong, K.-W.10
Kozu, G.11
Nakanishi, H.12
Kahn, M.13
Chi, E.Y.14
Henderson, W.R.15
-
107
-
-
0033530812
-
Syntheses and evaluation of amidinobenzofuran derivatives as tryptase inhibitors
-
S. Ono, S. Kuwahara, M. Takeuchi, H. Sakashita, Y. Naito, and T. Kondo Syntheses and evaluation of amidinobenzofuran derivatives as tryptase inhibitors Bioorg. Med. Chem. Lett. 9 1999 3285 3290
-
(1999)
Bioorg. Med. Chem. Lett.
, vol.9
, pp. 3285-3290
-
-
Ono, S.1
Kuwahara, S.2
Takeuchi, M.3
Sakashita, H.4
Naito, Y.5
Kondo, T.6
-
108
-
-
34247123987
-
A tick protein with a modified Kunitz fold inhibits human tryptase
-
G.C. Paesen, C. Siebold, K. Harlos, M.F. Peacey, P.A. Nuttall, and D.I. Stuart A tick protein with a modified Kunitz fold inhibits human tryptase J. Mol. Biol. 368 2007 1172 1186
-
(2007)
J. Mol. Biol.
, vol.368
, pp. 1172-1186
-
-
Paesen, G.C.1
Siebold, C.2
Harlos, K.3
Peacey, M.F.4
Nuttall, P.A.5
Stuart, D.I.6
-
109
-
-
33847324029
-
Critical role of dipeptidyl peptidase I in neutrophil recruitment during the development of experimental abdominal aortic aneurysms
-
M.B. Pagano, M.A. Bartoli, T.L. Ennis, D. Mao, P.M. Simmons, R.W. Thompson, and C.T. Pham Critical role of dipeptidyl peptidase I in neutrophil recruitment during the development of experimental abdominal aortic aneurysms Proc. Natl. Acad. Sci. USA 104 2007 2855 2860
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 2855-2860
-
-
Pagano, M.B.1
Bartoli, M.A.2
Ennis, T.L.3
Mao, D.4
Simmons, P.M.5
Thompson, R.W.6
Pham, C.T.7
-
110
-
-
0033525211
-
Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3
-
M. Pallaoro, M.S. Fejzo, L. Shayesteh, J.L. Blount, and G.H. Caughey Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3 J. Biol. Chem. 274 1999 3355 3362
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 3355-3362
-
-
Pallaoro, M.1
Fejzo, M.S.2
Shayesteh, L.3
Blount, J.L.4
Caughey, G.H.5
-
111
-
-
77958511663
-
Chymase inhibition prevents fibronectin and myofibrillar loss and improves cardiomyocyte function and LV torsion angle in dogs with isolated mitral regurgitation
-
B. Pat, Y. Chen, C. Killingsworth, J.D. Gladden, K. Shi, J. Zheng, P.C. Powell, G. Walcott, M.I. Ahmed, H. Gupta, R. Desai, C.C. Wei, N. Hase, T. Kobayashi, A. Sabri, H. Granzier, T. Denney, M. Tillson, A.R. Dillon, A. Husain, and L.J. Dell'italia Chymase inhibition prevents fibronectin and myofibrillar loss and improves cardiomyocyte function and LV torsion angle in dogs with isolated mitral regurgitation Circulation 122 2010 1488 1495
-
(2010)
Circulation
, vol.122
, pp. 1488-1495
-
-
Pat, B.1
Chen, Y.2
Killingsworth, C.3
Gladden, J.D.4
Shi, K.5
Zheng, J.6
Powell, P.C.7
Walcott, G.8
Ahmed, M.I.9
Gupta, H.10
Desai, R.11
Wei, C.C.12
Hase, N.13
Kobayashi, T.14
Sabri, A.15
Granzier, H.16
Denney, T.17
Tillson, M.18
Dillon, A.R.19
Husain, A.20
Dell'italia, L.J.21
more..
-
112
-
-
68149141332
-
Novel insights into the biological function of mast cell carboxypeptidase A
-
G. Pejler, S.D. Knight, F. Henningsson, and S. Wernersson Novel insights into the biological function of mast cell carboxypeptidase A Trends Immunol. 30 2009 401 408
-
(2009)
Trends Immunol.
, vol.30
, pp. 401-408
-
-
Pejler, G.1
Knight, S.D.2
Henningsson, F.3
Wernersson, S.4
-
113
-
-
77954663588
-
Mast cell proteases-multifaceted regulators of inflammatory disease
-
G. Pejler, E. Ronnberg, I. Waern, and S. Wernersson Mast cell proteases-multifaceted regulators of inflammatory disease Blood 115 2010 4981 4990
-
(2010)
Blood
, vol.115
, pp. 4981-4990
-
-
Pejler, G.1
Ronnberg, E.2
Waern, I.3
Wernersson, S.4
-
114
-
-
2642600031
-
Human beta-tryptase is a ring-like tetramer with active sites facing a central pore
-
P.J.B. Pereira, A. Bergner, S. Macedo-Ribeiro, R. Huber, G. Matschiner, H. Fritz, C.P. Sommerhoff, and W. Bode Human beta-tryptase is a ring-like tetramer with active sites facing a central pore Nature 392 1998 306 311
-
(1998)
Nature
, vol.392
, pp. 306-311
-
-
Pereira, P.J.B.1
Bergner, A.2
Macedo-Ribeiro, S.3
Huber, R.4
Matschiner, G.5
Fritz, H.6
Sommerhoff, C.P.7
Bode, W.8
-
115
-
-
10344234724
-
Papillon-Lefevre syndrome: Correlating the molecular, cellular, and clinical consequences of cathepsin C/dipeptidyl peptidase I deficiency in humans
-
C.T. Pham, J.L. Ivanovich, S.Z. Raptis, B. Zehnbauer, and T.J. Ley Papillon-Lefevre syndrome: correlating the molecular, cellular, and clinical consequences of cathepsin C/dipeptidyl peptidase I deficiency in humans J. Immunol. 173 2004 7277 7281
-
(2004)
J. Immunol.
, vol.173
, pp. 7277-7281
-
-
Pham, C.T.1
Ivanovich, J.L.2
Raptis, S.Z.3
Zehnbauer, B.4
Ley, T.J.5
-
116
-
-
0033587689
-
Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo
-
C.T. Pham, and T.J. Ley Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo Proc. Natl. Acad. Sci. USA 96 1999 8627 8632
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 8627-8632
-
-
Pham, C.T.1
Ley, T.J.2
-
117
-
-
41849095954
-
Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis
-
A.M. Piliponsky, C.C. Chen, T. Nishimura, M. Metz, E.J. Rios, P.R. Dobner, E. Wada, K. Wada, S. Zacharias, U.M. Mohanasundaram, J.D. Faix, M. Abrink, G. Pejler, R.G. Pearl, M. Tsai, and S.J. Galli Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis Nat. Med. 14 2008 392 398
-
(2008)
Nat. Med.
, vol.14
, pp. 392-398
-
-
Piliponsky, A.M.1
Chen, C.C.2
Nishimura, T.3
Metz, M.4
Rios, E.J.5
Dobner, P.R.6
Wada, E.7
Wada, K.8
Zacharias, S.9
Mohanasundaram, U.M.10
Faix, J.D.11
Abrink, M.12
Pejler, G.13
Pearl, R.G.14
Tsai, M.15
Galli, S.J.16
-
118
-
-
84865218566
-
The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis
-
A.M. Piliponsky, C.C. Chen, E.J. Rios, P.M. Treuting, A. Lahiri, M. Abrink, G. Pejler, M. Tsai, and S.J. Galli The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis Am. J. Pathol. 181 2012 875 886
-
(2012)
Am. J. Pathol.
, vol.181
, pp. 875-886
-
-
Piliponsky, A.M.1
Chen, C.C.2
Rios, E.J.3
Treuting, P.M.4
Lahiri, A.5
Abrink, M.6
Pejler, G.7
Tsai, M.8
Galli, S.J.9
-
119
-
-
0033830060
-
MMCP-8, the first lineage-specific differentiation marker for mouse basophils. Elevated numbers of potent IL-4-producing and MMCP-8-positive cells in spleens of malaria-infected mice
-
M. Poorafshar, H. Helmby, M. Troye-Blomberg, and L. Hellman MMCP-8, the first lineage-specific differentiation marker for mouse basophils. Elevated numbers of potent IL-4-producing and MMCP-8-positive cells in spleens of malaria-infected mice Eur. J. Immunol. 30 2000 2660 2668
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 2660-2668
-
-
Poorafshar, M.1
Helmby, H.2
Troye-Blomberg, M.3
Hellman, L.4
-
120
-
-
0021879888
-
Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors
-
J.C. Powers, T. Tanaka, J.W. Harper, Y. Minematsu, L. Barker, D. Lincoln, K.V. Crumley, J.E. Fraki, N.M. Schechter, G.G. Lazarus, K. Nakajima, K. Nakashino, H. Neurath, and R.G. Woodbury Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors Biochemistry 24 1985 2048 2058
-
(1985)
Biochemistry
, vol.24
, pp. 2048-2058
-
-
Powers, J.C.1
Tanaka, T.2
Harper, J.W.3
Minematsu, Y.4
Barker, L.5
Lincoln, D.6
Crumley, K.V.7
Fraki, J.E.8
Schechter, N.M.9
Lazarus, G.G.10
Nakajima, K.11
Nakashino, K.12
Neurath, H.13
Woodbury, R.G.14
-
121
-
-
0347445722
-
A genomic analysis of rat proteases and protease inhibitors
-
X.S. Puente, and C. Lopez-Otin A genomic analysis of rat proteases and protease inhibitors Genome Res. 14 2004 609 622
-
(2004)
Genome Res.
, vol.14
, pp. 609-622
-
-
Puente, X.S.1
Lopez-Otin, C.2
-
122
-
-
84892404434
-
Chymase activities and survival in endotoxin-induced human chymase transgenic mice
-
K. Rafiq, Y.Y. Fan, S.J. Sherajee, Y. Takahashi, J. Matsuura, N. Hase, H. Mori, D. Nakano, H. Kobara, H. Hitomi, T. Masaki, H. Urata, and A. Nishiyama Chymase activities and survival in endotoxin-induced human chymase transgenic mice Int. J. Med. Sci. 11 2014 222 225
-
(2014)
Int. J. Med. Sci.
, vol.11
, pp. 222-225
-
-
Rafiq, K.1
Fan, Y.Y.2
Sherajee, S.J.3
Takahashi, Y.4
Matsuura, J.5
Hase, N.6
Mori, H.7
Nakano, D.8
Kobara, H.9
Hitomi, H.10
Masaki, T.11
Urata, H.12
Nishiyama, A.13
-
123
-
-
84876222161
-
Mutational tail loss is an evolutionary mechanism for liberating marapsins and other type I serine proteases from transmembrane anchors
-
K. Raman, N.N. Trivedi, W.W. Raymond, R. Ganesan, D. Kirchhofer, G.M. Verghese, C.S. Craik, E.L. Schneider, S. Nimishakavi, and G.H. Caughey Mutational tail loss is an evolutionary mechanism for liberating marapsins and other type I serine proteases from transmembrane anchors J. Biol. Chem. 288 2013 10588 10598
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 10588-10598
-
-
Raman, K.1
Trivedi, N.N.2
Raymond, W.W.3
Ganesan, R.4
Kirchhofer, D.5
Verghese, G.M.6
Craik, C.S.7
Schneider, E.L.8
Nimishakavi, S.9
Caughey, G.H.10
-
124
-
-
0034659275
-
The kinetic and structural characterization of the reaction of nafamostat with bovine pancreatic trypsin
-
M.K. Ramjee, I.M. Henderson, S.B. McLoughlin, and A. Padova The kinetic and structural characterization of the reaction of nafamostat with bovine pancreatic trypsin Thromb. Res. 98 2000 559 569
-
(2000)
Thromb. Res.
, vol.98
, pp. 559-569
-
-
Ramjee, M.K.1
Henderson, I.M.2
McLoughlin, S.B.3
Padova, A.4
-
125
-
-
20444433960
-
Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering
-
S.Z. Raptis, S.D. Shapiro, P.M. Simmons, A.M. Cheng, and C.T. Pham Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering Immunity 22 2005 679 691
-
(2005)
Immunity
, vol.22
, pp. 679-691
-
-
Raptis, S.Z.1
Shapiro, S.D.2
Simmons, P.M.3
Cheng, A.M.4
Pham, C.T.5
-
126
-
-
33644979727
-
Mast cell and neutrophil peptidases attack an inactivation segment in hepatocyte growth factor to generate NK4-like antagonists
-
W.W. Raymond, A.C. Cruz, and G.H. Caughey Mast cell and neutrophil peptidases attack an inactivation segment in hepatocyte growth factor to generate NK4-like antagonists J. Biol. Chem. 281 2006 1489 1494
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 1489-1494
-
-
Raymond, W.W.1
Cruz, A.C.2
Caughey, G.H.3
-
127
-
-
13544256359
-
Mastin is a gelatinolytic mast cell peptidase resembling a mini-proteasome
-
W.W. Raymond, C.P. Sommerhoff, and G.H. Caughey Mastin is a gelatinolytic mast cell peptidase resembling a mini-proteasome Arch. Biochem. Biophys. 435 2005 311 322
-
(2005)
Arch. Biochem. Biophys.
, vol.435
, pp. 311-322
-
-
Raymond, W.W.1
Sommerhoff, C.P.2
Caughey, G.H.3
-
128
-
-
66949181206
-
Alpha2-macroglobulin capture allows detection of mast cell chymase in serum and creates a reservoir of angiotensin II-generating activity
-
W.W. Raymond, S. Su, A. Makarova, T.M. Wilson, M.C. Carter, D.D. Metcalfe, and G.H. Caughey Alpha2-macroglobulin capture allows detection of mast cell chymase in serum and creates a reservoir of angiotensin II-generating activity J. Immunol. 182 2009 5770 5777
-
(2009)
J. Immunol.
, vol.182
, pp. 5770-5777
-
-
Raymond, W.W.1
Su, S.2
Makarova, A.3
Wilson, T.M.4
Carter, M.C.5
Metcalfe, D.D.6
Caughey, G.H.7
-
129
-
-
0029042981
-
Purification and characterization of dog mast cell protease-3, an oligomeric relative of tryptases
-
W.W. Raymond, E.K. Tam, J.L. Blount, and G.H. Caughey Purification and characterization of dog mast cell protease-3, an oligomeric relative of tryptases J. Biol. Chem. 270 1995 13164 13170
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13164-13170
-
-
Raymond, W.W.1
Tam, E.K.2
Blount, J.L.3
Caughey, G.H.4
-
130
-
-
78149485386
-
How immune peptidases change specificity: Cathepsin G gained tryptic function but lost efficiency during primate evolution
-
W.W. Raymond, N.N. Trivedi, A. Makarova, M. Ray, C.S. Craik, and G.H. Caughey How immune peptidases change specificity: cathepsin G gained tryptic function but lost efficiency during primate evolution J. Immunol. 185 2010 5360 5368
-
(2010)
J. Immunol.
, vol.185
, pp. 5360-5368
-
-
Raymond, W.W.1
Trivedi, N.N.2
Makarova, A.3
Ray, M.4
Craik, C.S.5
Caughey, G.H.6
-
131
-
-
0346847766
-
Albumin is a substrate of human chymase: Prediction by combinatorial peptide screening and development of a selective inhibitor based on the albumin cleavage site
-
W.W. Raymond, S. Waugh Ruggles, C.S. Craik, and G.H. Caughey Albumin is a substrate of human chymase: prediction by combinatorial peptide screening and development of a selective inhibitor based on the albumin cleavage site J. Biol. Chem. 278 2003 34517 34524
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34517-34524
-
-
Raymond, W.W.1
Waugh Ruggles, S.2
Craik, C.S.3
Caughey, G.H.4
-
132
-
-
0020312338
-
Rapid conversion of angiotensin I to angiotensin II by neutrophil and mast cell proteinases
-
C.F. Reilly, D.A. Tewksbury, N.B. Schechter, and J. Travis Rapid conversion of angiotensin I to angiotensin II by neutrophil and mast cell proteinases J. Biol. Chem. 257 1982 8619 8622
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 8619-8622
-
-
Reilly, C.F.1
Tewksbury, D.A.2
Schechter, N.B.3
Travis, J.4
-
133
-
-
77953164767
-
High degree of conservation of the multigene tryptase locus over the past 150-200 million years of mammalian evolution
-
J.M. Reimer, P.B. Samollow, and L. Hellman High degree of conservation of the multigene tryptase locus over the past 150-200 million years of mammalian evolution Immunogenetics 62 2010 369 382
-
(2010)
Immunogenetics
, vol.62
, pp. 369-382
-
-
Reimer, J.M.1
Samollow, P.B.2
Hellman, L.3
-
134
-
-
0025212267
-
Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases
-
D.S. Reynolds, R.L. Stevens, W.S. Lane, M.H. Carr, K.F. Austen, and W.E. Serafin Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases Proc. Natl. Acad. Sci. USA 87 1990 3230 3234
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 3230-3234
-
-
Reynolds, D.S.1
Stevens, R.L.2
Lane, W.S.3
Carr, M.H.4
Austen, K.F.5
Serafin, W.E.6
-
135
-
-
84891705895
-
Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation
-
A. Roy, G. Ganesh, H. Sippola, S. Bolin, O. Sawesi, A. Dagalv, S.M. Schlenner, T. Feyerabend, H.R. Rodewald, L. Kjellen, L. Hellman, and M. Abrink Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation J. Biol. Chem. 289 2014 237 250
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 237-250
-
-
Roy, A.1
Ganesh, G.2
Sippola, H.3
Bolin, S.4
Sawesi, O.5
Dagalv, A.6
Schlenner, S.M.7
Feyerabend, T.8
Rodewald, H.R.9
Kjellen, L.10
Hellman, L.11
Abrink, M.12
-
136
-
-
84962706128
-
Familial hypertryptasemia with associated mast cell activation syndrome
-
V. Sabato, E. Van De Vijver, M. Hagendorens, I. Vrelust, E. Reyniers, E. Fransen, C. Bridts, L. De Clerck, G. Mortier, P. Valent, and D. Ebo Familial hypertryptasemia with associated mast cell activation syndrome J. Allergy 130 2012 410 420
-
(2012)
J. Allergy
, vol.130
, pp. 410-420
-
-
Sabato, V.1
Van De Vijver, E.2
Hagendorens, M.3
Vrelust, I.4
Reyniers, E.5
Fransen, E.6
Bridts, C.7
De Clerck, L.8
Mortier, G.9
Valent, P.10
Ebo, D.11
-
137
-
-
33745640026
-
Gene expression profiling of human mast cell subtypes: An in silico study
-
H. Saito, K. Matsumoto, S. Okumura, J. Kashiwakura, K. Oboki, H. Yokoi, N. Kambe, K. Ohta, and Y. Okayama Gene expression profiling of human mast cell subtypes: an in silico study Allergol. Int. 55 2006 173 179
-
(2006)
Allergol. Int.
, vol.55
, pp. 173-179
-
-
Saito, H.1
Matsumoto, K.2
Okumura, S.3
Kashiwakura, J.4
Oboki, K.5
Yokoi, H.6
Kambe, N.7
Ohta, K.8
Okayama, Y.9
-
138
-
-
0030068941
-
A novel heparin-dependent processing pathway for human tryptase: Autocatalysis followed by activation with dipeptidyl peptidase I
-
K. Sakai, S. Ren, and L.B. Schwartz A novel heparin-dependent processing pathway for human tryptase: autocatalysis followed by activation with dipeptidyl peptidase I J. Clin. Invest. 97 1996 988 995
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 988-995
-
-
Sakai, K.1
Ren, S.2
Schwartz, L.B.3
-
139
-
-
0037170771
-
Bivalent inhibition of beta-Tryptase: Distance scan of neighboring subunits by dibasic inhibitors
-
N. Schaschke, A. Dominik, G. Matschiner, and C.P. Sommerhoff Bivalent inhibition of beta-Tryptase: distance scan of neighboring subunits by dibasic inhibitors Bioorg. Med. Chem. Lett. 12 2002 985 988
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 985-988
-
-
Schaschke, N.1
Dominik, A.2
Matschiner, G.3
Sommerhoff, C.P.4
-
140
-
-
0025144597
-
Identification of a cathepsin G-like proteinase in the MCTC type of human mast cell
-
N.M. Schechter, A.M. Irani, J.L. Sprows, J. Abernethy, B. Wintroub, and L.B. Schwartz Identification of a cathepsin G-like proteinase in the MCTC type of human mast cell J. Immunol. 145 1990 2652 2661
-
(1990)
J. Immunol.
, vol.145
, pp. 2652-2661
-
-
Schechter, N.M.1
Irani, A.M.2
Sprows, J.L.3
Abernethy, J.4
Wintroub, B.5
Schwartz, L.B.6
-
141
-
-
35748944891
-
Molecular mechanism of mast cell mediated innate defense against endothelin and snake venom sarafotoxin
-
L.A. Schneider, S.M. Schlenner, T.B. Feyerabend, M. Wunderlin, and H.R. Rodewald Molecular mechanism of mast cell mediated innate defense against endothelin and snake venom sarafotoxin J. Exp. Med. 204 2007 2629 2639
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2629-2639
-
-
Schneider, L.A.1
Schlenner, S.M.2
Feyerabend, T.B.3
Wunderlin, M.4
Rodewald, H.R.5
-
142
-
-
33747331674
-
Diagnostic value of tryptase in anaphylaxis and mastocytosis
-
L.B. Schwartz Diagnostic value of tryptase in anaphylaxis and mastocytosis Immunol. Allergy Clin. N. Am. 26 2006 451 463
-
(2006)
Immunol. Allergy Clin. N. Am.
, vol.26
, pp. 451-463
-
-
Schwartz, L.B.1
-
143
-
-
0022872843
-
Regulation of tryptase from human lung mast cells by heparin. Stabilization of the active tetramer
-
L.B. Schwartz, and T.R. Bradford Regulation of tryptase from human lung mast cells by heparin. Stabilization of the active tetramer J. Biol. Chem. 261 1986 7372 7379
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 7372-7379
-
-
Schwartz, L.B.1
Bradford, T.R.2
-
144
-
-
0023262466
-
Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis
-
L.B. Schwartz, D.D. Metcalfe, J.S. Miller, H. Earl, and T. Sullivan Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis N. Engl. J. Med. 316 1987 1622 1626
-
(1987)
N. Engl. J. Med.
, vol.316
, pp. 1622-1626
-
-
Schwartz, L.B.1
Metcalfe, D.D.2
Miller, J.S.3
Earl, H.4
Sullivan, T.5
-
145
-
-
0038527434
-
Tryptase precursors are preferentially and spontaneously released, whereas mature tryptase is retained by HMC-1 cells, Mono-Mac-6 cells, and human skin-derived mast cells
-
L.B. Schwartz, H.K. Min, S. Ren, H.Z. Xia, J. Hu, W. Zhao, G. Moxley, and Y. Fukuoka Tryptase precursors are preferentially and spontaneously released, whereas mature tryptase is retained by HMC-1 cells, Mono-Mac-6 cells, and human skin-derived mast cells J. Immunol. 170 2003 5667 5673
-
(2003)
J. Immunol.
, vol.170
, pp. 5667-5673
-
-
Schwartz, L.B.1
Min, H.K.2
Ren, S.3
Xia, H.Z.4
Hu, J.5
Zhao, W.6
Moxley, G.7
Fukuoka, Y.8
-
146
-
-
0024547878
-
Time course of appearance and disappearance of human mast cell tryptase in the circulation after anaphylaxis
-
L.B. Schwartz, J.W. Yunginger, J. Miller, R. Bokhari, and D. Dull Time course of appearance and disappearance of human mast cell tryptase in the circulation after anaphylaxis J. Clin. Invest. 83 1989 1551 1555
-
(1989)
J. Clin. Invest.
, vol.83
, pp. 1551-1555
-
-
Schwartz, L.B.1
Yunginger, J.W.2
Miller, J.3
Bokhari, R.4
Dull, D.5
-
147
-
-
0346728517
-
Potent bivalent inhibition of human tryptase-beta by a synthetic inhibitor
-
T. Selwood, K.C. Elrod, and N.M. Schechter Potent bivalent inhibition of human tryptase-beta by a synthetic inhibitor Biol. Chem. 384 2003 1605 1611
-
(2003)
Biol. Chem.
, vol.384
, pp. 1605-1611
-
-
Selwood, T.1
Elrod, K.C.2
Schechter, N.M.3
-
148
-
-
0037353099
-
A potent tryptase inhibitor nafamostat mesilate dramatically suppressed pulmonary dysfunction induced in rats by a radiographic contrast medium
-
T. Sendo, Y. Itoh, T. Goromaru, T. Sumimura, M. Saito, K. Aki, T. Yano, and R. Oishi A potent tryptase inhibitor nafamostat mesilate dramatically suppressed pulmonary dysfunction induced in rats by a radiographic contrast medium Br. J. Pharmacol. 138 2003 959 967
-
(2003)
Br. J. Pharmacol.
, vol.138
, pp. 959-967
-
-
Sendo, T.1
Itoh, Y.2
Goromaru, T.3
Sumimura, T.4
Saito, M.5
Aki, K.6
Yano, T.7
Oishi, R.8
-
149
-
-
59849124392
-
Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes
-
K. Shin, P.A. Nigrovic, J. Crish, E. Boilard, H.P. McNeil, K.S. Larabee, R. Adachi, M.F. Gurish, R. Gobezie, R.L. Stevens, and D.M. Lee Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes J. Immunol. 182 2009 647 656
-
(2009)
J. Immunol.
, vol.182
, pp. 647-656
-
-
Shin, K.1
Nigrovic, P.A.2
Crish, J.3
Boilard, E.4
McNeil, H.P.5
Larabee, K.S.6
Adachi, R.7
Gurish, M.F.8
Gobezie, R.9
Stevens, R.L.10
Lee, D.M.11
-
150
-
-
0030948078
-
Chymase is activated in the hamster heart following ventricular fibrosis during the chronic stage of hypertension
-
N. Shiota, D. Jin, S. Takai, T. Kawamura, M. Koyama, N. Nakamura, and M. Miyazaki Chymase is activated in the hamster heart following ventricular fibrosis during the chronic stage of hypertension FEBS Lett. 406 1997 301 304
-
(1997)
FEBS Lett.
, vol.406
, pp. 301-304
-
-
Shiota, N.1
Jin, D.2
Takai, S.3
Kawamura, T.4
Koyama, M.5
Nakamura, N.6
Miyazaki, M.7
-
151
-
-
70450224855
-
Engineered cystine knot miniproteins as potent inhibitors of human mast cell tryptase beta
-
C.P. Sommerhoff, O. Avrutina, H.U. Schmoldt, D. Gabrijelcic-Geiger, U. Diederichsen, and H. Kolmar Engineered cystine knot miniproteins as potent inhibitors of human mast cell tryptase beta J. Mol. Biol. 395 2010 167 175
-
(2010)
J. Mol. Biol.
, vol.395
, pp. 167-175
-
-
Sommerhoff, C.P.1
Avrutina, O.2
Schmoldt, H.U.3
Gabrijelcic-Geiger, D.4
Diederichsen, U.5
Kolmar, H.6
-
152
-
-
0028520933
-
A Kazal-type inhibitor of human mast cell tryptase: Isolation from the medicinal leech Hirudo medicinalis, characterization, and sequence analysis
-
C.P. Sommerhoff, C. Sollner, R. Mentele, G.P. Piechottka, E.A. Auerswald, and H. Fritz A Kazal-type inhibitor of human mast cell tryptase: isolation from the medicinal leech Hirudo medicinalis, characterization, and sequence analysis Biol. Chem. Hoppe-Seyler 375 1994 685 694
-
(1994)
Biol. Chem. Hoppe-Seyler
, vol.375
, pp. 685-694
-
-
Sommerhoff, C.P.1
Sollner, C.2
Mentele, R.3
Piechottka, G.P.4
Auerswald, E.A.5
Fritz, H.6
-
153
-
-
0035987309
-
Genetic deficiency of human mast cell alpha-tryptase
-
D. Soto, C. Malmsten, J.L. Blount, D.J. Muilenburg, and G.H. Caughey Genetic deficiency of human mast cell alpha-tryptase Clin. Exp. Allergy 32 2002 1000 1006
-
(2002)
Clin. Exp. Allergy
, vol.32
, pp. 1000-1006
-
-
Soto, D.1
Malmsten, C.2
Blount, J.L.3
Muilenburg, D.J.4
Caughey, G.H.5
-
154
-
-
84860330769
-
Cathepsin G and neutrophil elastase contribute to lung-protective immunity against mycobacterial infections in mice
-
K. Steinwede, R. Maus, J. Bohling, S. Voedisch, A. Braun, M. Ochs, A. Schmiedl, F. Langer, F. Gauthier, J. Roes, T. Welte, F.C. Bange, M. Niederweis, F. Buhling, and U.A. Maus Cathepsin G and neutrophil elastase contribute to lung-protective immunity against mycobacterial infections in mice J. Immunol. 188 2012 4476 4487
-
(2012)
J. Immunol.
, vol.188
, pp. 4476-4487
-
-
Steinwede, K.1
Maus, R.2
Bohling, J.3
Voedisch, S.4
Braun, A.5
Ochs, M.6
Schmiedl, A.7
Langer, F.8
Gauthier, F.9
Roes, J.10
Welte, T.11
Bange, F.C.12
Niederweis, M.13
Buhling, F.14
Maus, U.A.15
-
155
-
-
34248183479
-
Protease-proteoglycan complexes of mouse and human mast cells and importance of their beta-tryptase-heparin complexes in inflammation and innate immunity
-
R.L. Stevens, and R. Adachi Protease-proteoglycan complexes of mouse and human mast cells and importance of their beta-tryptase-heparin complexes in inflammation and innate immunity Immunol. Rev. 217 2007 155 167
-
(2007)
Immunol. Rev.
, vol.217
, pp. 155-167
-
-
Stevens, R.L.1
Adachi, R.2
-
156
-
-
0028082425
-
Strain-specific and tissue-specific expression of mouse mast cell secretory granule proteases
-
R.L. Stevens, D.S. Friend, H.P. McNeil, V. Schiller, N. Ghildyal, and K.F. Austen Strain-specific and tissue-specific expression of mouse mast cell secretory granule proteases Proc. Natl. Acad. Sci. USA 91 1994 128 132
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 128-132
-
-
Stevens, R.L.1
Friend, D.S.2
McNeil, H.P.3
Schiller, V.4
Ghildyal, N.5
Austen, K.F.6
-
157
-
-
0030754090
-
The three-dimensional structure of recombinant leech-derived tryptase inhibitor in complex with trypsin. Implications for the structure of human mast cell tryptase and its inhibition
-
M.T. Stubbs, R. Morenweiser, J. Sturzebecher, M. Bauer, W. Bode, R. Huber, G.P. Piechottka, G. Matschiner, C.P. Sommerhoff, H. Fritz, and E.A. Auerswald The three-dimensional structure of recombinant leech-derived tryptase inhibitor in complex with trypsin. Implications for the structure of human mast cell tryptase and its inhibition J. Biol. Chem. 272 1997 19931 19937
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19931-19937
-
-
Stubbs, M.T.1
Morenweiser, R.2
Sturzebecher, J.3
Bauer, M.4
Bode, W.5
Huber, R.6
Piechottka, G.P.7
Matschiner, G.8
Sommerhoff, C.P.9
Fritz, H.10
Auerswald, E.A.11
-
158
-
-
84863012007
-
The alphavbeta6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells
-
K. Sugimoto, M. Kudo, A. Sundaram, X. Ren, K. Huang, X. Bernstein, Y. Wang, W.W. Raymond, D.J. Erle, M. Abrink, G.H. Caughey, X. Huang, and D. Sheppard The alphavbeta6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells J. Clin. Invest. 122 2012 748 758
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 748-758
-
-
Sugimoto, K.1
Kudo, M.2
Sundaram, A.3
Ren, X.4
Huang, K.5
Bernstein, X.6
Wang, Y.7
Raymond, W.W.8
Erle, D.J.9
Abrink, M.10
Caughey, G.H.11
Huang, X.12
Sheppard, D.13
-
159
-
-
70349763716
-
Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation
-
J. Sun, J. Zhang, J.S. Lindholt, G.K. Sukhova, J. Liu, A. He, M. Abrink, G. Pejler, R.L. Stevens, R.W. Thompson, T.L. Ennis, M.F. Gurish, P. Libby, and G.P. Shi Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation Circulation 120 2009 973 982
-
(2009)
Circulation
, vol.120
, pp. 973-982
-
-
Sun, J.1
Zhang, J.2
Lindholt, J.S.3
Sukhova, G.K.4
Liu, J.5
He, A.6
Abrink, M.7
Pejler, G.8
Stevens, R.L.9
Thompson, R.W.10
Ennis, T.L.11
Gurish, M.F.12
Libby, P.13
Shi, G.P.14
-
160
-
-
84904758041
-
Dipeptidyl peptidase I controls survival from Klebsiella pneumoniae lung infection by processing surfactant protein D
-
R.E. Sutherland, S.S. Barry, J.S. Olsen, D.B. Salantes, G.H. Caughey, and P.J. Wolters Dipeptidyl peptidase I controls survival from Klebsiella pneumoniae lung infection by processing surfactant protein D Biochem. Biophys. Res. Commun. 450 2014 818 823
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.450
, pp. 818-823
-
-
Sutherland, R.E.1
Barry, S.S.2
Olsen, J.S.3
Salantes, D.B.4
Caughey, G.H.5
Wolters, P.J.6
-
161
-
-
84864485117
-
Glandular mast cells with distinct phenotype are highly elevated in chronic rhinosinusitis with nasal polyps
-
T. Takabayashi, A. Kato, A.T. Peters, L.A. Suh, R. Carter, J. Norton, L.C. Grammer, B.K. Tan, R.K. Chandra, D.B. Conley, R.C. Kern, S. Fujieda, and R.P. Schleimer Glandular mast cells with distinct phenotype are highly elevated in chronic rhinosinusitis with nasal polyps J. Allergy Clin. Immunol. 130 2012 410 420
-
(2012)
J. Allergy Clin. Immunol.
, vol.130
, pp. 410-420
-
-
Takabayashi, T.1
Kato, A.2
Peters, A.T.3
Suh, L.A.4
Carter, R.5
Norton, J.6
Grammer, L.C.7
Tan, B.K.8
Chandra, R.K.9
Conley, D.B.10
Kern, R.C.11
Fujieda, S.12
Schleimer, R.P.13
-
162
-
-
15744388309
-
A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2
-
E. Tchougounova, A. Lundequist, I. Fajardo, J.O. Winberg, M. Abrink, and G. Pejler A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2 J. Biol. Chem. 280 2005 9291 9296
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 9291-9296
-
-
Tchougounova, E.1
Lundequist, A.2
Fajardo, I.3
Winberg, J.O.4
Abrink, M.5
Pejler, G.6
-
163
-
-
0041622832
-
The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover
-
E. Tchougounova, G. Pejler, and M. Abrink The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover J. Exp. Med. 198 2003 423 431
-
(2003)
J. Exp. Med.
, vol.198
, pp. 423-431
-
-
Tchougounova, E.1
Pejler, G.2
Abrink, M.3
-
164
-
-
34248194581
-
The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections
-
S.M. Thakurdas, E. Melicoff, L. Sansores-Garcia, D.C. Moreira, Y. Petrova, R.L. Stevens, and R. Adachi The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections J. Biol. Chem. 282 2007 20809 20815
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 20809-20815
-
-
Thakurdas, S.M.1
Melicoff, E.2
Sansores-Garcia, L.3
Moreira, D.C.4
Petrova, Y.5
Stevens, R.L.6
Adachi, R.7
-
165
-
-
84878301906
-
Chymase inhibition and cardiovascular protection
-
H. Tojo, and H. Urata Chymase inhibition and cardiovascular protection Cardiovasc. Drugs Ther. 27 2013 139 143
-
(2013)
Cardiovasc. Drugs Ther.
, vol.27
, pp. 139-143
-
-
Tojo, H.1
Urata, H.2
-
166
-
-
0020077967
-
Identification of a human neutrophil angiotension II-generating protease as cathepsin G
-
M.G. Tonnesen, M.S. Klempner, K.F. Austen, and B.U. Wintroub Identification of a human neutrophil angiotension II-generating protease as cathepsin G J. Clin. Invest. 69 1982 25 30
-
(1982)
J. Clin. Invest.
, vol.69
, pp. 25-30
-
-
Tonnesen, M.G.1
Klempner, M.S.2
Austen, K.F.3
Wintroub, B.U.4
-
167
-
-
0018215999
-
Human alpha-1-antichymotrypsin: Interaction with chymotrypsin-like proteinases
-
J. Travis, J. Bowen, and R. Baugh Human alpha-1-antichymotrypsin: interaction with chymotrypsin-like proteinases Biochemistry 17 1978 5651 5656
-
(1978)
Biochemistry
, vol.17
, pp. 5651-5656
-
-
Travis, J.1
Bowen, J.2
Baugh, R.3
-
168
-
-
0036188833
-
Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): An open-label pilot study
-
W.J. Tremaine, A. Brzezinski, J.A. Katz, D.C. Wolf, T.J. Fleming, J. Mordenti, L.C. Strenkoski-Nix, and M.C. Kurth Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): an open-label pilot study Aliment. Pharmacol. Ther. 16 2002 407 413
-
(2002)
Aliment. Pharmacol. Ther.
, vol.16
, pp. 407-413
-
-
Tremaine, W.J.1
Brzezinski, A.2
Katz, J.A.3
Wolf, D.C.4
Fleming, T.J.5
Mordenti, J.6
Strenkoski-Nix, L.C.7
Kurth, M.C.8
-
169
-
-
77249175436
-
Mast cell peptidases: Chameleons of innate immunity and host defense
-
N.N. Trivedi, and G.H. Caughey Mast cell peptidases: chameleons of innate immunity and host defense Am. J. Respir. Cell Mol. Biol. 42 2010 257 267
-
(2010)
Am. J. Respir. Cell Mol. Biol.
, vol.42
, pp. 257-267
-
-
Trivedi, N.N.1
Caughey, G.H.2
-
170
-
-
42749083932
-
Chimerism, point mutation, and truncation dramatically transformed mast cell delta-tryptases during primate evolution
-
N.N. Trivedi, W.W. Raymond, and G.H. Caughey Chimerism, point mutation, and truncation dramatically transformed mast cell delta-tryptases during primate evolution J. Allergy Clin. Immunol. 121 2008 1262 1268
-
(2008)
J. Allergy Clin. Immunol.
, vol.121
, pp. 1262-1268
-
-
Trivedi, N.N.1
Raymond, W.W.2
Caughey, G.H.3
-
171
-
-
71749098499
-
Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations
-
N.N. Trivedi, B. Tamraz, C. Chu, P.Y. Kwok, and G.H. Caughey Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations J. Allergy Clin. Immunol. 124 2009 1099 1105
-
(2009)
J. Allergy Clin. Immunol.
, vol.124
, pp. 1099-1105
-
-
Trivedi, N.N.1
Tamraz, B.2
Chu, C.3
Kwok, P.Y.4
Caughey, G.H.5
-
172
-
-
38449097058
-
Mast cell alpha and beta tryptases changed rapidly during primate speciation and evolved from gamma-like transmembrane peptidases in ancestral vertebrates
-
N.N. Trivedi, Q. Tong, K. Raman, V.J. Bhagwandin, and G.H. Caughey Mast cell alpha and beta tryptases changed rapidly during primate speciation and evolved from gamma-like transmembrane peptidases in ancestral vertebrates J. Immunol. 179 2007 6072 6079
-
(2007)
J. Immunol.
, vol.179
, pp. 6072-6079
-
-
Trivedi, N.N.1
Tong, Q.2
Raman, K.3
Bhagwandin, V.J.4
Caughey, G.H.5
-
173
-
-
17944366493
-
Structure of human dipeptidyl peptidase I (cathepsin C): Exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases
-
D. Turk, V. Janjic, I. Stern, M. Podobnik, D. Lamba, S.W. Dahl, C. Lauritzen, J. Pedersen, V. Turk, and B. Turk Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases EMBO J. 20 2001 6570 6582
-
(2001)
EMBO J.
, vol.20
, pp. 6570-6582
-
-
Turk, D.1
Janjic, V.2
Stern, I.3
Podobnik, M.4
Lamba, D.5
Dahl, S.W.6
Lauritzen, C.7
Pedersen, J.8
Turk, V.9
Turk, B.10
-
174
-
-
82755161948
-
Cysteine cathepsins: From structure, function and regulation to new frontiers
-
V. Turk, V. Stoka, O. Vasiljeva, M. Renko, T. Sun, B. Turk, and D. Turk Cysteine cathepsins: from structure, function and regulation to new frontiers Biochim. Biophys. Acta 1824 2012 68 88
-
(2012)
Biochim. Biophys. Acta
, vol.1824
, pp. 68-88
-
-
Turk, V.1
Stoka, V.2
Vasiljeva, O.3
Renko, M.4
Sun, T.5
Turk, B.6
Turk, D.7
-
175
-
-
73149124943
-
Basophils preferentially express mouse mast cell protease 11 among the mast cell tryptase family in contrast to mast cells
-
T. Ugajin, T. Kojima, K. Mukai, K. Obata, Y. Kawano, Y. Minegishi, Y. Eishi, H. Yokozeki, and H. Karasuyama Basophils preferentially express mouse mast cell protease 11 among the mast cell tryptase family in contrast to mast cells J. Leukoc. Biol. 86 2009 1417 1425
-
(2009)
J. Leukoc. Biol.
, vol.86
, pp. 1417-1425
-
-
Ugajin, T.1
Kojima, T.2
Mukai, K.3
Obata, K.4
Kawano, Y.5
Minegishi, Y.6
Eishi, Y.7
Yokozeki, H.8
Karasuyama, H.9
-
176
-
-
29844444785
-
Potent pruritogenic action of tryptase mediated by PAR-2 receptor and its involvement in anti-pruritic effect of nafamostat mesilate in mice
-
H. Ui, T. Andoh, J.B. Lee, H. Nojima, and Y. Kuraishi Potent pruritogenic action of tryptase mediated by PAR-2 receptor and its involvement in anti-pruritic effect of nafamostat mesilate in mice Eur. J. Pharmacol. 530 2006 172 178
-
(2006)
Eur. J. Pharmacol.
, vol.530
, pp. 172-178
-
-
Ui, H.1
Andoh, T.2
Lee, J.B.3
Nojima, H.4
Kuraishi, Y.5
-
177
-
-
79959598455
-
Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: A consensus proposal
-
P. Valent, C. Akin, M. Arock, K. Brockow, J.H. Butterfield, M.C. Carter, M. Castells, L. Escribano, K. Hartmann, P. Lieberman, B. Nedoszytko, A. Orfao, L.B. Schwartz, K. Sotlar, W.R. Sperr, M. Triggiani, R. Valenta, H.P. Horny, and D.D. Metcalfe Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal Int. Arch. Allergy Immunol. 157 2012 215 225
-
(2012)
Int. Arch. Allergy Immunol.
, vol.157
, pp. 215-225
-
-
Valent, P.1
Akin, C.2
Arock, M.3
Brockow, K.4
Butterfield, J.H.5
Carter, M.C.6
Castells, M.7
Escribano, L.8
Hartmann, K.9
Lieberman, P.10
Nedoszytko, B.11
Orfao, A.12
Schwartz, L.B.13
Sotlar, K.14
Sperr, W.R.15
Triggiani, M.16
Valenta, R.17
Horny, H.P.18
Metcalfe, D.D.19
-
178
-
-
0025368035
-
Human mast cell tryptase: Multiple cDNAs and genes reveal a multigene serine protease family
-
P. Vanderslice, S.M. Ballinger, E.K. Tam, S.M. Goldstein, C.S. Craik, and G.H. Caughey Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family Proc. Natl. Acad. Sci. USA 87 1990 3811 3815
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 3811-3815
-
-
Vanderslice, P.1
Ballinger, S.M.2
Tam, E.K.3
Goldstein, S.M.4
Craik, C.S.5
Caughey, G.H.6
-
179
-
-
0024328773
-
Molecular cloning of dog mast cell tryptase and a related protease: Structural evidence of a unique mode of serine protease activation
-
P. Vanderslice, C.S. Craik, J.A. Nadel, and G.H. Caughey Molecular cloning of dog mast cell tryptase and a related protease: structural evidence of a unique mode of serine protease activation Biochemistry 28 1989 4148 4155
-
(1989)
Biochemistry
, vol.28
, pp. 4148-4155
-
-
Vanderslice, P.1
Craik, C.S.2
Nadel, J.A.3
Caughey, G.H.4
-
180
-
-
33845308239
-
Prostasin regulates epithelial monolayer function: Cell-specific Gpld1-mediated secretion and functional role for the GPI anchor
-
G.M. Verghese, M.F. Gutknecht, and G.H. Caughey Prostasin regulates epithelial monolayer function: cell-specific Gpld1-mediated secretion and functional role for the GPI anchor Am. J. Physiol. Cell Physiol. 291 2006 1258 1270
-
(2006)
Am. J. Physiol. Cell Physiol.
, vol.291
, pp. 1258-1270
-
-
Verghese, G.M.1
Gutknecht, M.F.2
Caughey, G.H.3
-
181
-
-
1642362240
-
Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production
-
D. Voehringer, K. Shinkai, and R.M. Locksley Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production Immunity 20 2004 267 277
-
(2004)
Immunity
, vol.20
, pp. 267-277
-
-
Voehringer, D.1
Shinkai, K.2
Locksley, R.M.3
-
182
-
-
77249101819
-
Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammation
-
I. Waern, S. Jonasson, J. Hjoberg, A. Bucht, M. Abrink, G. Pejler, and S. Wernersson Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammation J. Immunol. 183 2009 6369 6376
-
(2009)
J. Immunol.
, vol.183
, pp. 6369-6376
-
-
Waern, I.1
Jonasson, S.2
Hjoberg, J.3
Bucht, A.4
Abrink, M.5
Pejler, G.6
Wernersson, S.7
-
183
-
-
84883190168
-
Mast cell chymase modulates IL-33 levels and controls allergic sensitization in dust-mite induced airway inflammation
-
I. Waern, A. Lundequist, G. Pejler, and S. Wernersson Mast cell chymase modulates IL-33 levels and controls allergic sensitization in dust-mite induced airway inflammation Mucosal Immunol. 6 2013 911 920
-
(2013)
Mucosal Immunol.
, vol.6
, pp. 911-920
-
-
Waern, I.1
Lundequist, A.2
Pejler, G.3
Wernersson, S.4
-
184
-
-
0036839437
-
Delta tryptase is expressed in multiple human tissues, and a recombinant form has proteolytic activity
-
H.W. Wang, H.P. McNeil, A. Husain, K. Liu, N. Tedla, P.S. Thomas, M. Raftery, G.C. King, Z.Y. Cai, and J.E. Hunt Delta tryptase is expressed in multiple human tissues, and a recombinant form has proteolytic activity J. Immunol. 169 2002 5145 5152
-
(2002)
J. Immunol.
, vol.169
, pp. 5145-5152
-
-
Wang, H.W.1
McNeil, H.P.2
Husain, A.3
Liu, K.4
Tedla, N.5
Thomas, P.S.6
Raftery, M.7
King, G.C.8
Cai, Z.Y.9
Hunt, J.E.10
-
185
-
-
77954641196
-
Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters
-
T. Wang, S.X. Han, S.F. Zhang, Y.Y. Ning, L. Chen, Y.J. Chen, G.M. He, D. Xu, J. An, T. Yang, X.H. Zhang, and F.Q. Wen Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters Respir. Res. 11 2010 36
-
(2010)
Respir. Res.
, vol.11
, pp. 36
-
-
Wang, T.1
Han, S.X.2
Zhang, S.F.3
Ning, Y.Y.4
Chen, L.5
Chen, Y.J.6
He, G.M.7
Xu, D.8
An, J.9
Yang, T.10
Zhang, X.H.11
Wen, F.Q.12
-
186
-
-
77951171609
-
Mast cell chymase limits the cardiac efficacy of Ang I-converting enzyme inhibitor therapy in rodents
-
C.C. Wei, N. Hase, Y. Inoue, E.W. Bradley, E. Yahiro, M. Li, N. Naqvi, P.C. Powell, K. Shi, Y. Takahashi, K. Saku, H. Urata, L.J. Dell'italia, and A. Husain Mast cell chymase limits the cardiac efficacy of Ang I-converting enzyme inhibitor therapy in rodents J. Clin. Invest. 120 2010 1229 1239
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1229-1239
-
-
Wei, C.C.1
Hase, N.2
Inoue, Y.3
Bradley, E.W.4
Yahiro, E.5
Li, M.6
Naqvi, N.7
Powell, P.C.8
Shi, K.9
Takahashi, Y.10
Saku, K.11
Urata, H.12
Dell'italia, L.J.13
Husain, A.14
-
187
-
-
0021137396
-
Angiotensin I conversion by human and rat chymotryptic proteinases
-
B.U. Wintroub, N.B. Schechter, G.S. Lazarus, C.E. Kaempfer, and L.B. Schwartz Angiotensin I conversion by human and rat chymotryptic proteinases J. Invest. Dermatol. 83 1984 336 339
-
(1984)
J. Invest. Dermatol.
, vol.83
, pp. 336-339
-
-
Wintroub, B.U.1
Schechter, N.B.2
Lazarus, G.S.3
Kaempfer, C.E.4
Schwartz, L.B.5
-
188
-
-
84867248955
-
Cathepsin G-regulated release of formyl peptide receptor agonists modulate neutrophil effector functions
-
J.C. Woloszynek, Y. Hu, and C.T. Pham Cathepsin G-regulated release of formyl peptide receptor agonists modulate neutrophil effector functions J. Biol. Chem. 287 2012 34101 34109
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 34101-34109
-
-
Woloszynek, J.C.1
Hu, Y.2
Pham, C.T.3
-
189
-
-
0034088336
-
Dipeptidyl peptidase I cleaves matrix-associated proteins and is expressed mainly by mast cells in normal dog airways
-
P.J. Wolters, M. Laig-Webster, and G.H. Caughey Dipeptidyl peptidase I cleaves matrix-associated proteins and is expressed mainly by mast cells in normal dog airways Am. J. Respir. Cell Mol. Biol. 22 2000 183 190
-
(2000)
Am. J. Respir. Cell Mol. Biol.
, vol.22
, pp. 183-190
-
-
Wolters, P.J.1
Laig-Webster, M.2
Caughey, G.H.3
-
190
-
-
0035947568
-
Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice
-
P.J. Wolters, C.T. Pham, D.J. Muilenburg, T.J. Ley, and G.H. Caughey Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice J. Biol. Chem. 276 2001 18551 18556
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18551-18556
-
-
Wolters, P.J.1
Pham, C.T.2
Muilenburg, D.J.3
Ley, T.J.4
Caughey, G.H.5
-
191
-
-
0032546934
-
Regulated expression, processing, and secretion of dog mast cell dipeptidyl peptidase I
-
P.J. Wolters, W.W. Raymond, J.L. Blount, and G.H. Caughey Regulated expression, processing, and secretion of dog mast cell dipeptidyl peptidase I J. Biol. Chem. 273 1998 15514 15520
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15514-15520
-
-
Wolters, P.J.1
Raymond, W.W.2
Blount, J.L.3
Caughey, G.H.4
-
192
-
-
0036830570
-
Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor alpha/signal transducer and activator of transcription (STAT) 6-dependent pathway
-
G.W. Wong, P.S. Foster, S. Yasuda, J.C. Qi, S. Mahalingam, E.A. Mellor, G. Katsoulotos, L. Li, J.A. Boyce, S.A. Krilis, and R.L. Stevens Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor alpha/signal transducer and activator of transcription (STAT) 6-dependent pathway J. Biol. Chem. 277 2002 41906 41915
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41906-41915
-
-
Wong, G.W.1
Foster, P.S.2
Yasuda, S.3
Qi, J.C.4
Mahalingam, S.5
Mellor, E.A.6
Katsoulotos, G.7
Li, L.8
Boyce, J.A.9
Krilis, S.A.10
Stevens, R.L.11
-
193
-
-
0032941449
-
Cloning of the human homolog of mouse transmembrane tryptase
-
G.W. Wong, Y. Tang, and R.L. Stevens Cloning of the human homolog of mouse transmembrane tryptase Int. Arch. Allergy Immunol. 118 1999 419 421
-
(1999)
Int. Arch. Allergy Immunol.
, vol.118
, pp. 419-421
-
-
Wong, G.W.1
Tang, Y.2
Stevens, R.L.3
-
194
-
-
1642576098
-
Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns
-
G.W. Wong, S. Yasuda, N. Morokawa, L. Li, and R.L. Stevens Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns J. Biol. Chem. 279 2004 2438 2452
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 2438-2452
-
-
Wong, G.W.1
Yasuda, S.2
Morokawa, N.3
Li, L.4
Stevens, R.L.5
-
195
-
-
0032742390
-
Inhibition of allergen-induced pulmonary responses by the selective tryptase inhibitor 1,5-bis-[4-[(3-carbamimidoyl-benzenesulfonylamino)-methyl]-phenoxy]-pentane (AMG-126737)
-
C.D. Wright, A.M. Havill, S.C. Middleton, M.A. Kashem, D.J. Dripps, W.M. Abraham, D.S. Thomson, and L.E. Burgess Inhibition of allergen-induced pulmonary responses by the selective tryptase inhibitor 1,5-bis-[4-[(3-carbamimidoyl-benzenesulfonylamino)-methyl]-phenoxy]-pentane (AMG-126737) Biochem. Pharmacol. 58 1999 1989 1996
-
(1999)
Biochem. Pharmacol.
, vol.58
, pp. 1989-1996
-
-
Wright, C.D.1
Havill, A.M.2
Middleton, S.C.3
Kashem, M.A.4
Dripps, D.J.5
Abraham, W.M.6
Thomson, D.S.7
Burgess, L.E.8
-
196
-
-
0029035748
-
Quantitation of tryptase, chymase, FceRIa, and FceRIg mRNAs in human mast cells and basophils by competitive reverse transcription-polymerase chain reaction
-
H.-Z. Xia, C.L. Kepley, K. Sakai, J. Chelliah, A.-M.A. Irani, and L.B. Schwartz Quantitation of tryptase, chymase, FceRIa, and FceRIg mRNAs in human mast cells and basophils by competitive reverse transcription-polymerase chain reaction J. Immunol. 154 1995 5472 5480
-
(1995)
J. Immunol.
, vol.154
, pp. 5472-5480
-
-
Xia, H.-Z.1
Kepley, C.L.2
Sakai, K.3
Chelliah, J.4
Irani, A.-M.A.5
Schwartz, L.B.6
-
197
-
-
80052157211
-
Protease phenotype of constitutive connective tissue and of induced mucosal mast cells in mice is regulated by the tissue
-
W. Xing, K.F. Austen, M.F. Gurish, and T.G. Jones Protease phenotype of constitutive connective tissue and of induced mucosal mast cells in mice is regulated by the tissue Proc. Natl. Acad. Sci. USA 108 2011 14210 14215
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 14210-14215
-
-
Xing, W.1
Austen, K.F.2
Gurish, M.F.3
Jones, T.G.4
-
198
-
-
78650634216
-
The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5
-
G. Younan, F. Suber, W. Xing, T. Shi, Y. Kunori, M. Abrink, G. Pejler, S.M. Schlenner, H.R. Rodewald, F.D. Moore Jr., R.L. Stevens, R. Adachi, K.F. Austen, and M.F. Gurish The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5 J. Immunol. 185 2010 7681 7690
-
(2010)
J. Immunol.
, vol.185
, pp. 7681-7690
-
-
Younan, G.1
Suber, F.2
Xing, W.3
Shi, T.4
Kunori, Y.5
Abrink, M.6
Pejler, G.7
Schlenner, S.M.8
Rodewald, H.R.9
Moore, Jr.F.D.10
Stevens, R.L.11
Adachi, R.12
Austen, K.F.13
Gurish, M.F.14
-
199
-
-
33646578415
-
Expression and characterization of recombinant gamma-tryptase
-
J. Yuan, J. Beltman, E. Gjerstad, M.T. Nguyen, J. Sampang, H. Chan, J.W. Janc, and J.M. Clark Expression and characterization of recombinant gamma-tryptase Protein Expr. Purif. 49 2006 47 54
-
(2006)
Protein Expr. Purif.
, vol.49
, pp. 47-54
-
-
Yuan, J.1
Beltman, J.2
Gjerstad, E.3
Nguyen, M.T.4
Sampang, J.5
Chan, H.6
Janc, J.W.7
Clark, J.M.8
-
200
-
-
79958142090
-
Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation
-
J. Zhang, J. Sun, J.S. Lindholt, G.K. Sukhova, M. Sinnamon, R.L. Stevens, R. Adachi, P. Libby, R.W. Thompson, and G.P. Shi Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation Circ. Res. 108 2011 1316 1327
-
(2011)
Circ. Res.
, vol.108
, pp. 1316-1327
-
-
Zhang, J.1
Sun, J.2
Lindholt, J.S.3
Sukhova, G.K.4
Sinnamon, M.5
Stevens, R.L.6
Adachi, R.7
Libby, P.8
Thompson, R.W.9
Shi, G.P.10
-
201
-
-
84899621580
-
Chymase mediates injury and mitochondrial damage in cardiomyocytes during acute ischemia/reperfusion in the dog
-
J. Zheng, C.C. Wei, N. Hase, K. Shi, C.R. Killingsworth, S.H. Litovsky, P.C. Powell, T. Kobayashi, C.M. Ferrario, A. Rab, I. Aban, J.F. Collawn, and L.J. Dell'italia Chymase mediates injury and mitochondrial damage in cardiomyocytes during acute ischemia/reperfusion in the dog PLoS One 9 2014 e94732
-
(2014)
PLoS One
, vol.9
-
-
Zheng, J.1
Wei, C.C.2
Hase, N.3
Shi, K.4
Killingsworth, C.R.5
Litovsky, S.H.6
Powell, P.C.7
Kobayashi, T.8
Ferrario, C.M.9
Rab, A.10
Aban, I.11
Collawn, J.F.12
Dell'italia, L.J.13
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