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Volumn 11, Issue , 2010, Pages

Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; CHYMASE; CHYMOSTATIN; DIPEPTIDYL CARBOXYPEPTIDASE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; MESSENGER RNA; OLIGOPEPTIDE; SERINE PROTEINASE INHIBITOR;

EID: 77954641196     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-11-36     Document Type: Article
Times cited : (32)

References (42)
  • 2
    • 26944462695 scopus 로고    scopus 로고
    • Simvastatin inhibits cigarette smoking-induced emphysema and pulmonary hypertension in rat lungs
    • 10.1164/rccm.200501-041OC, 16002570
    • Lee JH, Lee DS, Kim EK, Choe KH, Oh YM, Shim TS, Kim SE, Lee YS, Lee SD. Simvastatin inhibits cigarette smoking-induced emphysema and pulmonary hypertension in rat lungs. Am J Respir Crit Care Med 2005, 172:987-93. 10.1164/rccm.200501-041OC, 16002570.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 987-993
    • Lee, J.H.1    Lee, D.S.2    Kim, E.K.3    Choe, K.H.4    Oh, Y.M.5    Shim, T.S.6    Kim, S.E.7    Lee, Y.S.8    Lee, S.D.9
  • 3
    • 33846189409 scopus 로고    scopus 로고
    • Cigarette smoke upregulates pulmonary vascular matrix metalloproteinases via TNF-alpha signaling
    • 10.1152/ajplung.00539.2005, 16905636
    • Wright JL, Tai H, Wang R, Wang X, Churg A. Cigarette smoke upregulates pulmonary vascular matrix metalloproteinases via TNF-alpha signaling. Am J Physiol Lung Cell Mol Physiol 2007, 292:L125-33. 10.1152/ajplung.00539.2005, 16905636.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.292
    • Wright, J.L.1    Tai, H.2    Wang, R.3    Wang, X.4    Churg, A.5
  • 4
    • 33646378188 scopus 로고    scopus 로고
    • Vasoactive mediators and pulmonary hypertension after cigarette smoke exposure in the guinea pig
    • 10.1152/japplphysiol.00274.2005, 16210440
    • Wright JL, Tai H, Churg A. Vasoactive mediators and pulmonary hypertension after cigarette smoke exposure in the guinea pig. J Appl Physiol 2006, 100:672-8. 10.1152/japplphysiol.00274.2005, 16210440.
    • (2006) J Appl Physiol , vol.100 , pp. 672-678
    • Wright, J.L.1    Tai, H.2    Churg, A.3
  • 5
    • 4544281877 scopus 로고    scopus 로고
    • Chymase as a novel target for the prevention of vascular diseases
    • 10.1016/j.tips.2004.08.007, 15380935
    • Takai S, Jin D, Muramatsu M, Miyazaki M. Chymase as a novel target for the prevention of vascular diseases. Trends Pharmacol Sci 2004, 25:518-22. 10.1016/j.tips.2004.08.007, 15380935.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 518-522
    • Takai, S.1    Jin, D.2    Muramatsu, M.3    Miyazaki, M.4
  • 6
    • 4644289087 scopus 로고    scopus 로고
    • Therapeutic applications of chymase inhibitors in cardiovascular diseases and fibrosis
    • 10.1016/j.ejphar.2004.08.040, 15464056
    • Takai S, Jin D, Muramatsu M, Okamoto Y, Miyazaki M. Therapeutic applications of chymase inhibitors in cardiovascular diseases and fibrosis. Eur J Pharmacol 2004, 501:1-8. 10.1016/j.ejphar.2004.08.040, 15464056.
    • (2004) Eur J Pharmacol , vol.501 , pp. 1-8
    • Takai, S.1    Jin, D.2    Muramatsu, M.3    Okamoto, Y.4    Miyazaki, M.5
  • 7
    • 0035107611 scopus 로고    scopus 로고
    • A novel vascular smooth muscle chymase is upregulated in hypertensive rats
    • 10.1172/JCI9997, 208939, 11254670
    • Guo C, Ju H, Leung D, Massaeli H, Shi M, Rabinovitch M. A novel vascular smooth muscle chymase is upregulated in hypertensive rats. J Clin Invest 2001, 107:703-15. 10.1172/JCI9997, 208939, 11254670.
    • (2001) J Clin Invest , vol.107 , pp. 703-715
    • Guo, C.1    Ju, H.2    Leung, D.3    Massaeli, H.4    Shi, M.5    Rabinovitch, M.6
  • 8
    • 15844404186 scopus 로고    scopus 로고
    • Expression, localisation and function of ACE and chymase in normal and atherosclerotic human coronary arteries
    • 10.1016/j.vph.2005.01.011, 15792927
    • Borland JA, Kelsall C, Yacoub MH, Chester AH. Expression, localisation and function of ACE and chymase in normal and atherosclerotic human coronary arteries. Vascul Pharmacol 2005, 42:99-108. 10.1016/j.vph.2005.01.011, 15792927.
    • (2005) Vascul Pharmacol , vol.42 , pp. 99-108
    • Borland, J.A.1    Kelsall, C.2    Yacoub, M.H.3    Chester, A.H.4
  • 9
    • 33750032795 scopus 로고    scopus 로고
    • Pathological roles of angiotensin II produced by mast cell chymase and the effects of chymase inhibition in animal models
    • 10.1016/j.pharmthera.2006.05.008, 16837049
    • Miyazaki M, Takai S, Jin D, Muramatsu M. Pathological roles of angiotensin II produced by mast cell chymase and the effects of chymase inhibition in animal models. Pharmacol Ther 2006, 112:668-76. 10.1016/j.pharmthera.2006.05.008, 16837049.
    • (2006) Pharmacol Ther , vol.112 , pp. 668-676
    • Miyazaki, M.1    Takai, S.2    Jin, D.3    Muramatsu, M.4
  • 10
    • 33748041146 scopus 로고    scopus 로고
    • Role of chymase-dependent angiotensin II formation in monocrotaline-induced pulmonary hypertensive rats
    • 10.1203/01.pdr.0000219431.45075.d9, 16690960
    • Kishi K, Jin D, Takai S, Muramatsu M, Katayama H, Tamai H, Miyazaki M. Role of chymase-dependent angiotensin II formation in monocrotaline-induced pulmonary hypertensive rats. Pediatr Res 2006, 60:77-82. 10.1203/01.pdr.0000219431.45075.d9, 16690960.
    • (2006) Pediatr Res , vol.60 , pp. 77-82
    • Kishi, K.1    Jin, D.2    Takai, S.3    Muramatsu, M.4    Katayama, H.5    Tamai, H.6    Miyazaki, M.7
  • 11
    • 39949084326 scopus 로고    scopus 로고
    • Chymase induces profibrotic response via transforming growth factor-beta 1/Smad activation in rat cardiac fibroblasts
    • 10.1007/s11010-007-9676-2, 18057996
    • Zhao XY, Zhao LY, Zheng QS, Su JL, Guan H, Shang FJ, Niu XL, He YP, Lu XL. Chymase induces profibrotic response via transforming growth factor-beta 1/Smad activation in rat cardiac fibroblasts. Mol Cell Biochem 2008, 310:159-66. 10.1007/s11010-007-9676-2, 18057996.
    • (2008) Mol Cell Biochem , vol.310 , pp. 159-166
    • Zhao, X.Y.1    Zhao, L.Y.2    Zheng, Q.S.3    Su, J.L.4    Guan, H.5    Shang, F.J.6    Niu, X.L.7    He, Y.P.8    Lu, X.L.9
  • 14
    • 0142200007 scopus 로고    scopus 로고
    • Involvement of mast cell chymase in bleomycin-induced pulmonary fibrosis in mice
    • 10.1016/j.ejphar.2003.08.050, 14575803
    • Tomimori Y, Muto T, Saito K, Tanaka T, Maruoka H, Sumida M, Fukami H, Fukuda Y. Involvement of mast cell chymase in bleomycin-induced pulmonary fibrosis in mice. Eur J Pharmacol 2003, 478:179-85. 10.1016/j.ejphar.2003.08.050, 14575803.
    • (2003) Eur J Pharmacol , vol.478 , pp. 179-185
    • Tomimori, Y.1    Muto, T.2    Saito, K.3    Tanaka, T.4    Maruoka, H.5    Sumida, M.6    Fukami, H.7    Fukuda, Y.8
  • 15
    • 34547133973 scopus 로고    scopus 로고
    • Chymase-positive mast cells play a role in the vascular component of airway remodeling in asthma
    • 10.1016/j.jaci.2007.04.021, 17559912
    • Zanini A, Chetta A, Saetta M, Baraldo S, D'Ippolito R, Castagnaro A, Neri M, Olivieri D. Chymase-positive mast cells play a role in the vascular component of airway remodeling in asthma. J Allergy Clin Immunol 2007, 120:329-33. 10.1016/j.jaci.2007.04.021, 17559912.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 329-333
    • Zanini, A.1    Chetta, A.2    Saetta, M.3    Baraldo, S.4    D'Ippolito, R.5    Castagnaro, A.6    Neri, M.7    Olivieri, D.8
  • 16
    • 0037700156 scopus 로고    scopus 로고
    • Structure and function of small airways in smokers: relationship between air trapping at CT and airway inflammation
    • 10.1148/radiol.2281020187, 12750458
    • Berger P, Laurent F, Begueret H, Perot V, Rouiller R, Raherison C, Molimard M, Marthan R, Tunon-de-Lara JM. Structure and function of small airways in smokers: relationship between air trapping at CT and airway inflammation. Radiology 2003, 228:85-94. 10.1148/radiol.2281020187, 12750458.
    • (2003) Radiology , vol.228 , pp. 85-94
    • Berger, P.1    Laurent, F.2    Begueret, H.3    Perot, V.4    Rouiller, R.5    Raherison, C.6    Molimard, M.7    Marthan, R.8    Tunon-de-Lara, J.M.9
  • 18
    • 0031960673 scopus 로고    scopus 로고
    • Roles of vascular angiotensin converting enzyme and chymase in two-kidney, one clip hypertensive hamsters
    • 10.1097/00004872-199816050-00013, 9797177
    • Jin D, Takai S, Shiota N, Miyazaki M. Roles of vascular angiotensin converting enzyme and chymase in two-kidney, one clip hypertensive hamsters. J Hypertens 1998, 16:657-64. 10.1097/00004872-199816050-00013, 9797177.
    • (1998) J Hypertens , vol.16 , pp. 657-664
    • Jin, D.1    Takai, S.2    Shiota, N.3    Miyazaki, M.4
  • 20
    • 0034126770 scopus 로고    scopus 로고
    • Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor
    • 10.1038/76282, 10835689
    • Cowan KN, Heilbut A, Humpl T, Lam C, Ito S, Rabinovitch M. Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor. Nat Med 2000, 6:698-702. 10.1038/76282, 10835689.
    • (2000) Nat Med , vol.6 , pp. 698-702
    • Cowan, K.N.1    Heilbut, A.2    Humpl, T.3    Lam, C.4    Ito, S.5    Rabinovitch, M.6
  • 21
    • 0037967318 scopus 로고    scopus 로고
    • Chymase is upregulated in diabetic nephropathy: implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease
    • 10.1097/01.ASN.0000071512.93927.4E, 12819233
    • Huang XR, Chen WY, Truong LD, Lan HY. Chymase is upregulated in diabetic nephropathy: implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease. J Am Soc Nephrol 2003, 14:1738-47. 10.1097/01.ASN.0000071512.93927.4E, 12819233.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1738-1747
    • Huang, X.R.1    Chen, W.Y.2    Truong, L.D.3    Lan, H.Y.4
  • 22
    • 0036806825 scopus 로고    scopus 로고
    • Transgenic study of the function of chymase in heart remodeling
    • 10.1097/00004872-200210000-00025, 12359984
    • Chen LY, Li P, He Q, Jiang LQ, Cui CJ, Xu L, Liu LS. Transgenic study of the function of chymase in heart remodeling. J Hypertens 2002, 20:2047-55. 10.1097/00004872-200210000-00025, 12359984.
    • (2002) J Hypertens , vol.20 , pp. 2047-2055
    • Chen, L.Y.1    Li, P.2    He, Q.3    Jiang, L.Q.4    Cui, C.J.5    Xu, L.6    Liu, L.S.7
  • 23
    • 0032528052 scopus 로고    scopus 로고
    • Cloning of the gene and cDNA for hamster chymase 2, and expression of chymase 1, chymase 2 and angiotensin-converting enzyme in the terminal stage of cardiomyopathic hearts
    • 1219600, 9657983
    • Shiota N, Fukamizu A, Okunishi H, Takai S, Murakami K, Miyazaki M. Cloning of the gene and cDNA for hamster chymase 2, and expression of chymase 1, chymase 2 and angiotensin-converting enzyme in the terminal stage of cardiomyopathic hearts. Biochem J 1998, 333(Pt 2):417-24. 1219600, 9657983.
    • (1998) Biochem J , vol.333 , Issue.PT 2 , pp. 417-424
    • Shiota, N.1    Fukamizu, A.2    Okunishi, H.3    Takai, S.4    Murakami, K.5    Miyazaki, M.6
  • 24
    • 34047121150 scopus 로고    scopus 로고
    • Renin-angiotensin system and cardiovascular risk
    • 10.1016/S0140-6736(07)60242-6, 17416265
    • Schmieder RE, Hilgers KF, Schlaich MP, Schmidt BM. Renin-angiotensin system and cardiovascular risk. Lancet 2007, 369:1208-19. 10.1016/S0140-6736(07)60242-6, 17416265.
    • (2007) Lancet , vol.369 , pp. 1208-1219
    • Schmieder, R.E.1    Hilgers, K.F.2    Schlaich, M.P.3    Schmidt, B.M.4
  • 25
    • 67650889307 scopus 로고    scopus 로고
    • Transition from atherosclerosis to aortic aneurysm in humans coincides with an increased expression of RAS components
    • 10.1016/j.atherosclerosis.2009.01.003, 19193379
    • Kaschina E, Scholz H, Steckelings UM, Sommerfeld M, Kemnitz UR, Artuc M, Schmidt S, Unger T. Transition from atherosclerosis to aortic aneurysm in humans coincides with an increased expression of RAS components. Atherosclerosis 2009, 205:396-403. 10.1016/j.atherosclerosis.2009.01.003, 19193379.
    • (2009) Atherosclerosis , vol.205 , pp. 396-403
    • Kaschina, E.1    Scholz, H.2    Steckelings, U.M.3    Sommerfeld, M.4    Kemnitz, U.R.5    Artuc, M.6    Schmidt, S.7    Unger, T.8
  • 26
    • 22044445561 scopus 로고    scopus 로고
    • Pulmonary hypertension in chronic obstructive pulmonary disease: current theories of pathogenesis and their implications for treatment
    • 10.1136/thx.2005.042994, 1747459, 15994270
    • Wright JL, Levy RD, Churg A. Pulmonary hypertension in chronic obstructive pulmonary disease: current theories of pathogenesis and their implications for treatment. Thorax 2005, 60:605-9. 10.1136/thx.2005.042994, 1747459, 15994270.
    • (2005) Thorax , vol.60 , pp. 605-609
    • Wright, J.L.1    Levy, R.D.2    Churg, A.3
  • 27
    • 33644862480 scopus 로고    scopus 로고
    • Smoking, metalloproteinases, and vascular disease
    • 10.1161/01.ATV.0000199268.27395.4f, 16339501
    • Perlstein TS, Lee RT. Smoking, metalloproteinases, and vascular disease. Arterioscler Thromb Vasc Biol 2006, 26:250-6. 10.1161/01.ATV.0000199268.27395.4f, 16339501.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 250-256
    • Perlstein, T.S.1    Lee, R.T.2
  • 28
    • 15944380115 scopus 로고    scopus 로고
    • Exposure to tobacco-derived materials induces overproduction of secreted proteinases in mast cells
    • 10.1016/j.taap.2004.09.003, 15808520
    • Small-Howard A, Turner H. Exposure to tobacco-derived materials induces overproduction of secreted proteinases in mast cells. Toxicol Appl Pharmacol 2005, 204:152-63. 10.1016/j.taap.2004.09.003, 15808520.
    • (2005) Toxicol Appl Pharmacol , vol.204 , pp. 152-163
    • Small-Howard, A.1    Turner, H.2
  • 29
    • 33746289310 scopus 로고    scopus 로고
    • Chymase: a new pharmacologic target in cardiovascular disease
    • 10.1097/01.crd.0000195220.62533.c5, 16788331
    • Bacani C, Frishman WH. Chymase: a new pharmacologic target in cardiovascular disease. Cardiol Rev 2006, 14:187-93. 10.1097/01.crd.0000195220.62533.c5, 16788331.
    • (2006) Cardiol Rev , vol.14 , pp. 187-193
    • Bacani, C.1    Frishman, W.H.2
  • 30
    • 0030897985 scopus 로고    scopus 로고
    • Cleavage of type I procollagen by human mast cell chymase initiates collagen fibril formation and generates a unique carboxyl-terminal propeptide
    • 10.1074/jbc.272.11.7127, 9054407
    • Kofford MW, Schwartz LB, Schechter NM, Yager DR, Diegelmann RF, Graham MF. Cleavage of type I procollagen by human mast cell chymase initiates collagen fibril formation and generates a unique carboxyl-terminal propeptide. J Biol Chem 1997, 272:7127-31. 10.1074/jbc.272.11.7127, 9054407.
    • (1997) J Biol Chem , vol.272 , pp. 7127-7131
    • Kofford, M.W.1    Schwartz, L.B.2    Schechter, N.M.3    Yager, D.R.4    Diegelmann, R.F.5    Graham, M.F.6
  • 31
    • 0034995590 scopus 로고    scopus 로고
    • Activation of paracrine TGF-beta1 signaling upon stimulation and degranulation of rat serosal mast cells: a novel function for chymase
    • 10.1096/fj.00-0273com, 11387235
    • Lindstedt KA, Wang Y, Shiota N, Saarinen J, Hyytiainen M, Kokkonen JO, Keski-Oja J, Kovanen PT. Activation of paracrine TGF-beta1 signaling upon stimulation and degranulation of rat serosal mast cells: a novel function for chymase. FASEB J 2001, 15:1377-88. 10.1096/fj.00-0273com, 11387235.
    • (2001) FASEB J , vol.15 , pp. 1377-1388
    • Lindstedt, K.A.1    Wang, Y.2    Shiota, N.3    Saarinen, J.4    Hyytiainen, M.5    Kokkonen, J.O.6    Keski-Oja, J.7    Kovanen, P.T.8
  • 32
    • 1242306647 scopus 로고    scopus 로고
    • The role of transforming growth factor beta in lung development and disease
    • 10.1378/chest.125.2.754, 14769761
    • Bartram U, Speer CP. The role of transforming growth factor beta in lung development and disease. Chest 2004, 125:754-65. 10.1378/chest.125.2.754, 14769761.
    • (2004) Chest , vol.125 , pp. 754-765
    • Bartram, U.1    Speer, C.P.2
  • 33
    • 33745808765 scopus 로고    scopus 로고
    • Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosis
    • 10.1513/pats.200601-008AW, 2658705, 16799084
    • Sheppard D. Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosis. Proc Am Thorac Soc 2006, 3:413-7. 10.1513/pats.200601-008AW, 2658705, 16799084.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 413-417
    • Sheppard, D.1
  • 34
    • 33845473487 scopus 로고    scopus 로고
    • Cigarette smoke drives small airway remodeling by induction of growth factors in the airway wall
    • 10.1164/rccm.200605-585OC, 17008639
    • Churg A, Tai H, Coulthard T, Wang R, Wright JL. Cigarette smoke drives small airway remodeling by induction of growth factors in the airway wall. Am J Respir Crit Care Med 2006, 174:1327-34. 10.1164/rccm.200605-585OC, 17008639.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 1327-1334
    • Churg, A.1    Tai, H.2    Coulthard, T.3    Wang, R.4    Wright, J.L.5
  • 35
    • 0037512313 scopus 로고    scopus 로고
    • Chymase inhibition prevents cardiac fibrosis and improves diastolic dysfunction in the progression of heart failure
    • 10.1161/01.CIR.0000074041.81728.79, 12742989
    • Matsumoto T, Wada A, Tsutamoto T, Ohnishi M, Isono T, Kinoshita M. Chymase inhibition prevents cardiac fibrosis and improves diastolic dysfunction in the progression of heart failure. Circulation 2003, 107:2555-8. 10.1161/01.CIR.0000074041.81728.79, 12742989.
    • (2003) Circulation , vol.107 , pp. 2555-2558
    • Matsumoto, T.1    Wada, A.2    Tsutamoto, T.3    Ohnishi, M.4    Isono, T.5    Kinoshita, M.6
  • 37
    • 0028672813 scopus 로고
    • Amino acid and peptide phosphonate derivatives as specific inhibitors of serine peptidases
    • full_text, 7845224
    • Oleksyszyn J, Powers JC. Amino acid and peptide phosphonate derivatives as specific inhibitors of serine peptidases. Methods Enzymol 1994, 244:423-41. full_text, 7845224.
    • (1994) Methods Enzymol , vol.244 , pp. 423-441
    • Oleksyszyn, J.1    Powers, J.C.2
  • 38
    • 0023916551 scopus 로고
    • Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium
    • 10.1083/jcb.106.5.1659, 2115066, 2967299
    • Lyons RM, Keski-Oja J, Moses HL. Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium. J Cell Biol 1988, 106:1659-65. 10.1083/jcb.106.5.1659, 2115066, 2967299.
    • (1988) J Cell Biol , vol.106 , pp. 1659-1665
    • Lyons, R.M.1    Keski-Oja, J.2    Moses, H.L.3
  • 39
    • 0344172844 scopus 로고    scopus 로고
    • Inhibitors of chymase as mast cell-stabilizing agents: contribution of chymase in the activation of human mast cells
    • He S, Gaca MD, McEuen AR, Walls AF. Inhibitors of chymase as mast cell-stabilizing agents: contribution of chymase in the activation of human mast cells. J Pharmacol Exp Ther 1999, 291:517-23.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 517-523
    • He, S.1    Gaca, M.D.2    McEuen, A.R.3    Walls, A.F.4
  • 40
    • 0024519165 scopus 로고
    • Identification of proteases that process distinct epitopes on the same protein
    • Takahashi H, Cease KB, Berzofsky JA. Identification of proteases that process distinct epitopes on the same protein. J Immunol 1989, 142:2221-9.
    • (1989) J Immunol , vol.142 , pp. 2221-2229
    • Takahashi, H.1    Cease, K.B.2    Berzofsky, J.A.3
  • 41
    • 0035859791 scopus 로고    scopus 로고
    • Functional evidence for a role of vascular chymase in the production of angiotensin II in isolated human arteries
    • 10.1161/hc3201.094971, 11502696
    • Richard V, Hurel-Merle S, Scalbert E, Ferry G, Lallemand F, Bessou JP, Thuillez C. Functional evidence for a role of vascular chymase in the production of angiotensin II in isolated human arteries. Circulation 2001, 104:750-2. 10.1161/hc3201.094971, 11502696.
    • (2001) Circulation , vol.104 , pp. 750-752
    • Richard, V.1    Hurel-Merle, S.2    Scalbert, E.3    Ferry, G.4    Lallemand, F.5    Bessou, J.P.6    Thuillez, C.7
  • 42
    • 50949114137 scopus 로고    scopus 로고
    • Endothelin-1 (1-31): from chymase-dependent synthesis to cardiovascular pathologies
    • 10.1016/j.vph.2008.06.007, 18675382
    • D'Orleans-Juste P, Houde M, Rae GA, Bkaily G, Carrier E, Simard E. Endothelin-1 (1-31): from chymase-dependent synthesis to cardiovascular pathologies. Vascul Pharmacol 2008, 49:51-62. 10.1016/j.vph.2008.06.007, 18675382.
    • (2008) Vascul Pharmacol , vol.49 , pp. 51-62
    • D'Orleans-Juste, P.1    Houde, M.2    Rae, G.A.3    Bkaily, G.4    Carrier, E.5    Simard, E.6


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