Mast cell expression of gelatinases A and B is regulated by kit ligand and TGF-β

Journal of Immunology

Volumn 162, Issue 9, 1999, Pages 5528-5535

  Fang, Kenneth C ^a,b   Wolters, Paul J ^a,b   Steinhoff, Martin ^b   Bidgol, Afshin ^a   Blount, John L ^a   Caughey, George H ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHYMASE; GELATINASE A; GELATINASE B; TRANSFORMING GROWTH FACTOR BETA;

ANGIOGENESIS; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ACTIVATION; DOG; ENZYME DEGRADATION; ENZYME INDUCTION; IMMUNOHISTOCHEMISTRY; MAST CELL; MASTOCYTOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; TISSUE INJURY;

ANIMALS; CHYMASES; COLLAGENASES; DOGS; DRUG SYNERGISM; ENZYME INDUCTION; GELATINASES; LUNG; MAST CELLS; MAST-CELL SARCOMA; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; METALLOENDOPEPTIDASES; ORGAN SPECIFICITY; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION; STEM CELL FACTOR; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0033136337     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. Matrisian, L. M. 1990. Metalloproteinases and their inhibitors in matrix remodeling. Trends Genet. 6:121.
2. Fini, E. M., M. T. Girard, M. Matsubara, and J. D. Bartlett. 1995. Unique regulation of the matrix metalloproteinase, gelatinase B. Invest. Ophthalmol. Vis. Sci. 36:622.
3. Matsubara, M., M. T. Girard, C. L. Kublin, C. Cintron, and M. E. Fini. 1991. Differential roles for two gelatinolytic enzymes of the matrix metalloproteinase family in the remodelling cornea. Dev. Biol. 147:425.
4. Moutsiakis, D., P. Mancuso, H. Krutzsch, W. Stetler-Stevenson, and S. Zucker. 1992. Characterization of metalloproteinases and tissue inhibitors of metalloproteinases in human plasma. Connect. Tissue Res. 28:213.
5. Welgus, H., E. Campbell, J. Cury, A. Eisen, R. Senior, S. Wilhelm, and G. Goldberg. 1990. Neutral metalloproteinases produced by human mononuclear phagocytes. J. Clin. Invest. 86:1496.
6. Stahle-Backdahl, M., S. D. Sudbeck, A. Z. Eisen, H. G. Welgus, and W. C. Parks. 1992. Expression of 92-kDa type IV collagenase mRNA by eosinophils associated with basal cell carcinoma. J. Invest. Dermatol. 99:497.
7. Hibbs, M. S., K. A. Hasty, J. S. Seyer, A. H. Karg, and C. L. Mainardi. 1985. Biochemical and immunological characterization of the secreted forms of human neutrophil gelatinase. J. Biol. Chem, 260:2493.
8. Weeks, B. S., H. W. Schnaper, M. Handy, E. Holloway, and H. K. Kleinman. 1993. Human T lymphocytes synthesize the 92 kDa type IV collagenase (gelatinase B). J. Cell. Physiol. 157:644.
9. Murphy, G., and A. J. P. Docherty. 1992. The matrix metalloproteinases and their inhibitors. Am. J. Respir. Cell Mol. Biol. 7:120.
10. Wahl, S. M., J. B. Allen, B. S. Weeks, H. L. Wong, and P. E. Klotman. 1993. Transforming growth factor βenhanes integrin expression and type IV collagenase secretion in human monocytes. Proc. Natl. Acad. Sci. USA 90:4577.
11. Saarialho-Kere, U. K., H. G. Welgus, and W. C. Parks. 1993. Distinct mechanisms regulate interstitial collagenase and 92-kDa gelatinase expression in human monocytic-like cells exposed to bacterial endotoxin. J. Biol. Chem. 268:17354.
12. Ogata, Y., J. J. Enghild, and H. Nagase. 1992. Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9. J. Biol. Chem. 267:3581.
13. Suzuki, K., J. J. Enghild, T. Morodomi, G. Salvesen, and H. Nagase. 1990. Mechanisms of activation of tissue procollagenase by matrix metalloproteinase 3 (stromelysin). Biochemistry 29:10261.
14. Sang, Q.-X., H. Birkedal-Hansen, and H. E. Van Wart. 1995. Proteolytic and non-proteolytic activation of human neutrophil progelatinase B. Biochim. Biophys. Acta 1251:99.
15. Springman, E. B., E. L. Angelton, H. Birkedal-Hansen, and H. E. Van Wart. 1990. Multiple modes of activation of latent fibroblast collagenase: evidence for the role of a Cys 73 active-site zinc complex in latency and "cysteine switch" mechanisms for activation. Proc. Natl. Acad. Sci. USA 87:364.
16. Pei, D., and S. Weiss. 1995. Furin-dependent intracellular activation of the human stromelysin-3 zymogen. Nature 375:244.
17. He, C., S. M. Wilhelm, and A. P. Pentland. 1989. Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc. Natl. Acad. Sci. USA 66:2632.
18. Sato, H., T. Takine, Y. Okada, J. Cao, A. Shinagawa, E. Yamamoto, and M. Seiki. 1994. A matrix metalloproteinase expressed on the surface of invasive tumor cells. Nature 370:61.
19. Schulman, E. S. 1993. The role of mast cells in inflammatory responses in the lung. Crit. Rev. Immunol. 13:35.
20. Kawanami, O., V. J. Ferrans, J. D. Fulmer, and R. G. Crystal. 1979. Ultrastructure of pulmonary mast cells in patients with fibrotic lung disorders. Lab. Invest. 40:717.
21. Heard, B. E., A. Dewar, and B. Corrin. 1992. Apposition of fibroblasts to mast cells and lymphocytes in normal human lung and in cryptogenic fibrosing alveolitis: ultrastructure and cell perimeter measurements. J. Pathol. 166:303.
22. Metcalfe, D., D. Baram, and Y. A. Mekori. 1997. Mast cells. Physiol. Rev. 77: 1033.
23. Hamawy, M. M., S. E. Mergenhagen, and R. P. Siraganian. 1995. Protein tyrosine phosphorylation as a mechanism of signalling in mast cells and basophils. Cell. Signal. 7:535.
24. Vliagoftis, H., A. S. Worobec, and D. D. Metcalfe. 1997. The protooncogene c-kit and c-kit ligand in human disease. J. Allergy Clin. Immunol. 100:435.
25. Fang, K. C., W. W. Raymond, S. C. Lazarus, and G. H. Caughey. 1996. Dog mastocytoma cells secrete a 92-kD gelatinase activated extracellularly by mast cell chymase. J. Clin. Invest. 97:1589.
26. 92 bonds of the catalytic domain. J. Biol. Chem. 272:25628.
27. Caughey, G. H., J. L. Blount, K. L. Koerber, M. Kitamura, and K. C. Fang. 1997. Cloning and expression of the dog mast cell α-chymase gene. J. Immunol. 159: 4367.
28. Caughey, G. H., N. F. Viro, S. C. Lazarus, and J. A. Nadel. 1988. Purification and characterization of dog mastocytoma chymase: identification of an octapeptide conserved in chymotryptic leukocyte proteinases. Biochim. Biophys. Acta 952: 142.
29. Caughey, G. H., N. F. Viro, J. Ramachandran, S. C. Lazarus, D. B. Borson, and J. A. Nadel. 1987. Dog mastocytoma tryptase: affinity purification, characterization and amino-terminal sequence. Arch. Biochem. Biophys. 258:555.
30. Caughey, G. H., W. W. Raymond, and P. Vanderslice. 1990. Dog mast cell chymase: molecular cloning and characterization. Biochemistry 29:5166.
31. Coughlan, A., D. Robertson, R. Burke, R. Beynon, and S. Carter. 1998. Isolation and identification of canine matrix metalloproteinase-2 (MMP-2). Vet. J. 155: 231.
32. Pennington, D. W., A. R. Lopez, P. S. Thomas, C. Peck, and W. M. Gold. 1992. Dog mastocytoma cells produce transforming growth factor β 1. J. Clin. Invest. 90:35.
33. Matin, R., E. K. Tam, J. A. Nadel, and G. H. Caughey. 1992. Distribution of chymase-containing mast cells in human bronchi. J. Histochem. Cytochem. 40: 781.
34. Yao, P. M., J. M. Buhler, M. P. d'Ortho, F. Lebargy, C. Delclaux, A. Harf, and C. Lafuma. 1996. Expression of matrix metalloproleinase gelatinases A and B by cultured epithelial cells from human bronchial expiants. J. Biol. Chem. 271: 15580.
35. Border, W. A., and N. A. Noble. 1994. Transforming growth factor β in tissue fibrosis. N. Engl. J. Med. 331:1286.
36. Mekori, Y. A., and D. D. Metcalfe. 1994. Transforming growth factor-β prevents stem cell factor-mediated rescue of mast cells from apoptosis after IL-3 deprivation. J. Immunol. 153:2194.
37. Xie, B., Z. Dong, and I. J. Fidler. 1994. Regulatory mechanisms for the expression of type IV collagenases/gelatinases in murine macrophages. J. Immunol. 152:3637.
38. Shimizu, S., Y. Nishikawa, K. Kuroda, S. Takagi, K. Kozaki, S. Hyuga, S. Saga, and M. Matsuyama. 1996. Involvement of transforming growth factor β1 in autocrine enhancement of gelalinase B secretion by murine metastatic colon carcinoma cells. Cancer Res. 56:3366.
39. Strongin, A. Y., I. Collier, G. Bannikov, B. L. Marmer, G. A. Grant, and G. I. Goldberg. 1995. Mechanism of cell surface activation of 72-kDa type IV collagenase. J. Biol. Chem. 270:5331.
40. Tozzi, C. A., S. Thakker-Varia, S. Y. Yu, R. F. Bannett, B. W. Peng, G. J. Poiani, F. J. Wilson, and D. J. Riley. 1998. Mast cell collagenase correlates with regression of pulmonary vascular remodeling in the rat. Am. J. Respir. Cell Mol. Biol. 18:497.
41. Brownell, E., L. Fiorentino, G. Jolly, K. Wolfe, S. Kincaid, P. Seperack, and D. Visco. 1995. Immunolocalization of stromelysin-related protein in murine mast cell granules. Int. Arch. Allergy Immunol. 107:333.
42. Sang, Q. A., M. K. Bodden, and J. L. Windsor. 1996. Activation of human progelatinase A by collagenase and matrilysin: activation of procollagenase by matrilysin. J. Protein Chem. 15:243.
43. Shapiro, S. D., C. J. Fliszar, T. J. Broekelmann, R. P. Mecham, R. M. Senior, and H. G. Welgus. 1995. Activation of the 92-kDa gelatinase by stromelysin and 4-aminophenylmercuric acetate. J. Biol. Chem. 270:6351.
44. Iemura, A., M. Tsai, A. Ando, B. K. Wershil, and S. J. Galli. 1994. The c-kit ligand, stem cell factor, promotes mast cell survival by suppressing apoptosis. Am. J. Pathol. 144:321.
45. Lukacs, N. W., R. M. Stricter, P. M. Lincoln, E. Brownell, D. M. Pullen, H. J. Schock, S. W. Chensue, D. D. Taub, and S. L. Kunkel. 1996. Stem cell factor (c-kit ligand) influences eosinophil recruitment and histamine levels in allergic airway inflammation. J. Immunol. 156:3945.
46. Wen, L. P., J. A. Fahrni, S. Matsui, and G. D. Rosen. 1996. Airway epithelial cells produce stem cell factor. Biochim. Biophys. Acta 1314:183.
47. Gruber, B. L., M. J. Marchese, K. Suzuki, L. B. Schwartz, Y. Okada, H. Nagase, and N. S. Ramamurthy. 1989. Synovial procollagenase activation by human mast cell tryptase dependence upon matrix metalloproteinase 3 activation. J. Clin. Invest. 84:1657.
48. Longley, B. J., L. Tyrrell, S. Lu, Y. Ma, V. Klump, and G. F. Murphy. 1997. Chronically kit-stimulated clonally-derived human mast cells show heterogeneity in different tissue microenvironments. J. Invest. Dermatol. 108:792.
49. Frey, R. S., and K. M. Mulder. 1997. Involvement of extracellular signal-regulated kinase 2 and stress-activated protein kinase Jun N-terminal kinase activation by transforming growth factor β in the negative growth control of breast cells. Cancer Res. 57:628.
50. Atfi, A., S. Djelloul, E. Chastre, R. R. Davis, and C. Gespach. 1997. Evidence for a role of Rho-like GTPases and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) in transforming growth factor β-mediated signaling. J. Biol. Chem. 272:1429.
51. Kim, S.-J., P. Angel, R. Lafyatis, K. Hattori, K. Y. Kim, M. B. Sporn, M. Karin, and A. B. Roberts. 1990. Autoinduction of transforming growth factor β1 is mediated by the AP-1 complex. Mol. Cell Biol. 10:1492.
52. Olofsson, A., K. Miyazono, T. Kanzaki, P. Colosetti, U. Engström, and C. Heldin. 1992. Transforming growth factor-β1, -β2, and -β3 secreted by a human glioblastoma cell line: identification of small and different forms of large latent complexes. J. Biol. Chem. 267:19482.
53. Gentry, L. E., and B. W. Nash. 1990. The pro domain of pre-pro-transforming growth factor β1 when independently expressed is a functional binding protein for the mature growth factor. Biochemistry 29:6831.
54. Crawford, S. E., V. Stellmach, J. E. Murphy-Ullrich, S. M. Ribeiro, J. Lawler, R. O. Hynes, G. P. Boivin, and N. Bouck. 1998. Thrombospondin-1 is a major activator of TGF-β1 in vivo. Cell 93:1159.
55. Vu, T. H., J. M. Shipley, G. Bergers, J. E. Berger, J. A. Helms, D. Hanahan, S. D. Shapiro, R. M. Senior, and Z. Werb. 1998. MMP9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell 93:411.
56. Taipale, J., J. Lohi, J. Saarinen, P. T. Kovanen, and J. Keski-Oja. 1995. Human mast cell chymase and leukocyte elastase release latent transforming growth factor-β1 from the extracellular matrix of cultured human epithelial and endothelial cells. J. Biol. Chem. 270:4689.
57. Hu, Z.-Q., T. Yamazaki, Z. Cai, T. Yoshida, and T. Shimamura. 1994. Mast cells display natural suppressor activity partially by releasing transforming growth factor-β. Immunology 82:482.
58. Grande, J., D. Melder, A. Zinsmeister, and P. Killen. 1993. Transforming growth factor-β1 induces collagen IV gene expression in NIH 3T3 cells. Lab. Invest. 69:387.
59. Gordon, J. R., and S. J. Galli. 1994. Promotion of mouse fibroblast collagen gene expression by mast cells stimulated via the Fc∈RI: role for mast cell-derived transforming growth factor β and tumor necrosis factor α. J. Exp. Med. 180:2027.
60. Stampfer, M. R., P. Yawen, M. Alhadeff, and J. Hosoda. 1993. TGFβ induction of extracellular matrix associated proteins in normal and transformed human mammary epithelial cells in culture is independent of growth effects. J. Cell. Physiol. 155:210.