The kinetic and structural characterization of the reaction of nafamostat with bovine pancreatic trypsin

Thrombosis Research

Volumn 98, Issue 6, 2000, Pages 559-569

  Ramjee, Manoj K ^a   Henderson, Ian M J ^a   McLoughlin, Sheila B ^a   Padova, Alessandro ^a  

^a Peptide Therapeutics Ltd   (United Kingdom)

Author keywords

Acyl enzyme intermediate; Kinetics; Nafamostat; Trypsin

Indexed keywords

NAFAMSTAT; NAFAMSTAT MESILATE; TRYPSIN;

ARTICLE; CATTLE; CHEMICAL REACTION KINETICS; COMPETITIVE INHIBITION; ENZYME INHIBITION; ENZYME KINETICS; KINETICS; PRIORITY JOURNAL;

ANIMALS; ANTICOAGULANTS; BENZOATES; BINDING SITES; CATTLE; GUANIDINES; KINETICS; MASS SPECTROMETRY; MODELS, CHEMICAL; MOLECULAR STRUCTURE; NAPHTHOLS; PANCREAS; SERINE PROTEINASE INHIBITORS; SPECTRUM ANALYSIS; SUBSTRATE SPECIFICITY; TRYPSIN;

EID: 0034659275     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(00)00206-1     Document Type: Article

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