Protease phenotype of constitutive connective tissue and of induced mucosal mast cells in mice is regulated by the tissue

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 34, 2011, Pages 14210-14215

  Xing, Wei ^a   Austen, K Frank ^a   Gurish, Michael F ^a   Jones, Tatiana G ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYPEPTIDASE A3; MOUSE MAST CELL PROTEASE 1; MOUSE MAST CELL PROTEASE 2; MOUSE MAST CELL PROTEASE 4; MOUSE MAST CELL PROTEASE 6; MOUSE MAST CELL PROTEASE 7; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONNECTIVE TISSUE CELL; CONTROLLED STUDY; INTESTINE; LUNG; MAST CELL; MOUSE; MUCOSA CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN; T LYMPHOCYTE; TISSUE; TRACHEA;

AEROSOLS; ALUM COMPOUNDS; ANIMALS; ANTIBODY SPECIFICITY; ANTIGENS; BRONCHI; CELL COUNT; CELL DIFFERENTIATION; CONNECTIVE TISSUE CELLS; IMMUNIZATION; MAST CELLS; MICE; MICE, INBRED BALB C; MUCOUS MEMBRANE; ORGAN SPECIFICITY; OVALBUMIN; PEPTIDE HYDROLASES; PHENOTYPE; STEM CELLS; TIME FACTORS; TRACHEA;

MUS; VERMES;

EID: 80052157211     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1111048108     Document Type: Article

References (52)

1. Enerbäck L (1966) Mast cells in rat gastrointestinal mucosa. 2. Dye-binding and metachromatic properties. Acta Pathol Microbiol Scand 66:303-312.
2. Reynolds DS, et al. (1990) Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases. Proc Natl Acad Sci USA 87:3230-3234.
3. Stevens RL (1991) Gene expression in different populations of mouse mast cells. Ann N Y Acad Sci 629:31-37.
4. Friend DS, et al. (1996) Mast cells that reside at different locations in the jejunum of mice infected with Trichinella spiralis exhibit sequential changes in their granule ultrastructure and chymase phenotype. J Cell Biol 135:279-290. (Pubitemid 26337754)
5. Friend DS, et al. (1998) Reversible expression of tryptases and chymases in the jejunal mast cells of mice infected with Trichinella spiralis. J Immunol 160:5537-5545. (Pubitemid 28267847)
6. Stevens RL, et al. (1994) Strain-specific and tissue-specific expression of mouse mast cell secretory granule proteases. Proc Natl Acad Sci USA 91:128-132. (Pubitemid 24018656)
7. Gurish MF, et al. (1995) Tissue-regulated differentiation and maturation of a v-abl-immortalized mast cell-committed progenitor. Immunity 3:175-186.
8. Knight PA, Wright SH, Lawrence CE, Paterson YY, Miller HR (2000) Delayed expulsion of the nematode Trichinella spiralis in mice lacking the mucosal mast cell-specific granule chymase, mouse mast cell protease-1. J Exp Med 192:1849-1856. (Pubitemid 32049777)
9. Groschwitz KR, et al. (2009) Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism. Proc Natl Acad Sci USA 106:22381-22386.
10. Tchougounova E, Pejler G, Abrink M (2003) The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover. J Exp Med 198:423-431. (Pubitemid 36976053)
11. Waern I, et al. (2009) Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammation. J Immunol 183:6369-6376.
12. Huang C, et al. (1998) Induction of a selective and persistent extravasation of neutrophils into the peritoneal cavity by tryptase mouse mast cell protease 6. J Immunol 160:1910-1919. (Pubitemid 28106480)
13. Thakurdas SM, et al. (2007) The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections. J Biol Chem 282:20809-20815. (Pubitemid 47099914)
14. Huang C, et al. (2001) Evaluation of the substrate specificity of human mast cell tryptase beta I and demonstration of its importance in bacterial infections of the lung. J Biol Chem 276:26276-26284.
15. Irani AA, Schechter NM, Craig SS, DeBlois G, Schwartz LB (1986) Two types of human mast cells that have distinct neutral protease compositions. Proc Natl Acad Sci USA 83:4464-4468. (Pubitemid 16057069)
16. Irani AM, Goldstein SM, Wintroub BU, Bradford T, Schwartz LB (1991) Human mast cell carboxypeptidase. Selective localization to MCTC cells. J Immunol 147:247-253.
17. Irani AM, et al. (1987) Deficiency of the tryptase-positive, chymase-negative mast cell type in gastrointestinal mucosa of patients with defective T lymphocyte function. J Immunol 138:4381-4386.
18. Dougherty RH, et al. (2010) Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma. J Allergy Clin Immunol 125:1046-1053.
19. Abonia JP, et al. (2010) Involvement of mast cells in eosinophilic esophagitis. J Allergy Clin Immunol 126:140-149.
20. Pae S, et al. (2010) Chronic allergen challenge induces bronchial mast cell accumulation in BALB/c but not C57BL/6 mice and is independent of IL-9. Immunogenetics 62:499-506.
21. Yu M, et al. (2006) Mast cells can promote the development of multiple features of chronic asthma in mice. J Clin Invest 116:1633-1641.
22. Hallgren J, et al. (2007) Pulmonary CXCR2 regulates VCAM-1 and antigen-induced recruitment of mast cell progenitors. Proc Natl Acad Sci USA 104:20478-20483.
23. Abonia JP, et al. (2006) Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung. Blood 108:1588-1594. (Pubitemid 44316126)
24. Jones TG, et al. (2009) Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells. J Immunol 183:5251-5260.
25. Ikeda RK, et al. (2003) Accumulation of peribronchial mast cells in a mouse model of ovalbumin allergen induced chronic airway inflammation: modulation by immunostimulatory DNA sequences. J Immunol 171:4860-4867. (Pubitemid 37310608)
26. Wershil BK, Murakami T, Galli SJ (1988) Mast cell-dependent amplification of an immunologically nonspecific inflammatory response. Mast cells are required for the full expression of cutaneous acute inflammation induced by phorbol 12-myristate 13-acetate. J Immunol 140:2356-2360. (Pubitemid 18098498)
27. Ghildyal N, et al. (1994) Lack of expression of the tryptase mouse mast cell protease 7 in mast cells of the C57BL/6J mouse. J Immunol 153:2624-2630. (Pubitemid 24278132)
28. Scudamore CL, et al. (1997) Mast cell heterogeneity in the gastrointestinal tract: Variable expression of mouse mast cell protease-1 (mMCP-1) in intraepithelial mucosal mast cells in nematode-infected and normal BALB/c mice. Am J Pathol 150:1661-1672. (Pubitemid 27193814)
29. Huntley JF, et al. (1990) Distribution of intestinal mast cell proteinase in blood and tissues of normal and Trichinella-infected mice. Parasite Immunol 12:85-95. (Pubitemid 20030677)
30. Wilkes LK, McMenamin C, Holt PG (1992) Postnatal maturation of mast cell subpopulations in the rat respiratory tract. Immunology 75:535-541.
31. Eklund KK, Ghildyal N, Austen KF, Stevens RL (1993) Induction by IL-9 and suppression by IL-3 and IL-4 of the levels of chromosome 14-derived transcripts that encode late-expressed mouse mast cell proteases. J Immunol 151:4266-4273. (Pubitemid 23298760)
32. Ghildyal N, McNeil HP, Gurish MF, Austen KF, Stevens RL (1992) Transcriptional regulation of the mucosal mast cell-specific protease gene, MMCP-2, by interleukin 10 and interleukin 3. J Biol Chem 267:8473-8477.
33. Ghildyal N, et al. (1992) IL-10 induces transcription of the gene for mouse mast cell protease-1, a serine protease preferentially expressed in mucosal mast cells of Trichinella spiralis-infected mice. J Immunol 149:2123-2129.
34. Miller HR, Wright SH, Knight PA, Thornton EM (1999) A novel function for transforming growth factor-beta1: Upregulation of the expression and the IgE-independent extracellular release of a mucosal mast cell granule-specific beta-chymase, mouse mast cell protease-1. Blood 93:3473-3486. (Pubitemid 29220915)
35. Munger JS, et al. (1999) The integrin alpha v beta 6 binds and activates latent TGF beta 1: A mechanism for regulating pulmonary inflammation and fibrosis. Cell 96:319-328. (Pubitemid 29077586)
36. Dayton ET, et al. (1988) 3T3 fibroblasts induce cloned interleukin 3-dependent mouse mast cells to resemble connective tissue mast cells in granular constituency. Proc Natl Acad Sci USA 85:569-572.
37. Gurish MF, et al. (1992) Differential expression of secretory granule proteases in mouse mast cells exposed to interleukin 3 and c-kit ligand. J Exp Med 175:1003-1012.
38. Kaieda S, et al. (2010) Synovial fibroblasts promote the expression and granule accumulation of tryptase via interleukin-33 and its receptor ST-2 (IL1RL1). J Biol Chem 285:21478-21486.
39. Kitamura Y, Hirota S, Nishida T (2001) A loss-of-function mutation of c-kit results in depletion of mast cells and interstitial cells of Cajal, while its gain-of-function mutation results in their oncogenesis. Mutat Res 477:165-171. (Pubitemid 32480199)
40. Gorelik L, Flavell RA (2000) Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity 12:171-181. (Pubitemid 30398631)
41. Shin K, et al. (2009) Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes. J Immunol 182:647-656.
42. Oh SW, et al. (2002) Tryptase inhibition blocks airway inflammation in a mouse asthma model. J Immunol 168:1992-2000.
43. Chen CL, et al. (2006) Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma. J Allergy Clin Immunol 118:105-112.
44. Krishna MT, et al. (2001) Inhibition of mast cell tryptase by inhaled APC 366 attenuates allergen-induced late-phase airway obstruction in asthma. J Allergy Clin Immunol 107:1039-1045. (Pubitemid 32523345)
45. Mukundan C, Gurish MF, Austen KF, Hechtman HB, Friend DS (2001) Mast cell mediation of muscle and pulmonary injury following hindlimb ischemia-reperfusion. J Histochem Cytochem 49:1055-1056. (Pubitemid 32675012)
46. McDermott JR, et al. (2003) Mast cells disrupt epithelial barrier function during enteric nematode infection. Proc Natl Acad Sci USA 100:7761-7766. (Pubitemid 36760043)
47. Stevens RL, et al. (1996) Transgenic mice that possess a disrupted mast cell protease 5 (mMCP-5) gene cannot store carboxypeptidase A in their granules. FASEB J 10:1307.
48. Gurish MF, et al. (2001) Intestinal mast cell progenitors require CD49dbeta7 (α4β7 integrin) for tissue-specific homing. J Exp Med 194:1243-1252. (Pubitemid 33055043)
49. Ghildyal N, Friend DS, Nicodemus CF, Austen KF, Stevens RL (1993) Reversible expression of mouse mast cell protease 2 mRNA and protein in cultured mast cells exposed to IL-10. J Immunol 151:3206-3214. (Pubitemid 23282633)
50. Forsberg E, et al. (1999) Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme. Nature 400:773-776. (Pubitemid 29399539)
51. McNeil HP, Frenkel DP, Austen KF, Friend DS, Stevens RL (1992) Translation and granule localization of mouse mast cell protease-5. Immunodetection with specific antipeptide Ig. J Immunol 149:2466-2472.
52. Ghildyal N, et al. (1996) Fate of two mast cell tryptases in V3 mastocytosis and normal BALB/c mice undergoing passive systemic anaphylaxis: Prolonged retention of exocytosed mMCP-6 in connective tissues, and rapid accumulation of enzymatically active mMCP-7 in the blood. J Exp Med 184:1061-1073.