Targeting xenobiotic receptors PXR and CAR in human diseases

Drug Discovery Today

Volumn 20, Issue 5, 2015, Pages 618-628

  Banerjee, Monimoy ^a   Robbins, Delira ^a   Chen, Taosheng ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONSTITUTIVE ANDROSTANE RECEPTOR; PREGNANE X RECEPTOR; CELL RECEPTOR; LIGAND; PROTEIN BINDING; STEROID RECEPTOR;

APOPTOSIS; DRUG DESIGN; DRUG METABOLISM; GLUCONEOGENESIS; HUMAN; IN VITRO STUDY; INFLAMMATORY BOWEL DISEASE; LIVER CLEARANCE; LIVER INJURY; LONG TERM CARE; NONHUMAN; PROGNOSIS; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REVIEW; RISK ASSESSMENT; ULCERATIVE COLITIS; XENOBIOTIC METABOLISM; BINDING SITE; BIOTRANSFORMATION; CHEMISTRY; DRUG EFFECTS; DRUG INTERACTION; METABOLISM; MOLECULARLY TARGETED THERAPY; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

BINDING SITES; BIOTRANSFORMATION; DRUG DESIGN; DRUG INTERACTIONS; HUMANS; LIGANDS; MOLECULAR TARGETED THERAPY; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTOR CROSS-TALK; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84929155646     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2014.11.011     Document Type: Review

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