Structural and functional analysis of the human nuclear xenobiotic receptor PXR in complex with RXRα

Journal of Molecular Biology

Volumn 425, Issue 14, 2013, Pages 2561-2577

  Wallace, Bret D ^a   Betts, Laurie ^a   Talmage, Garrick ^a   Pollet, Rebecca M ^a   Holman, Natalie S ^a   Redinbo, Matthew R ^a  

^a University of North Carolina at Chapel Hill   (United States)

Author keywords

CYP3A4; DNA; nuclear receptor; transcription factor; X ray crystallography

Indexed keywords

HETERODIMER; NUCLEAR PROTEIN; NUCLEAR RECEPTOR PXR; RETINOID X RECEPTOR ALPHA; STEROID RECEPTOR COACTIVATOR 1; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DNA BINDING; DNA SEQUENCE; HUMAN; LIGAND BINDING; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; TRANSCRIPTION REGULATION;

BACTERIA (MICROORGANISMS);

EID: 84879552015     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.04.012     Document Type: Article

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