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Volumn 21, Issue 9, 2007, Pages 2099-2111

The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4α in the regulation of human steroid-/bile acid-sulfotransferase

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CELL NUCLEUS RECEPTOR; CONSTITUTIVE ANDROSTANE RECEPTOR; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; PREGNANE X RECEPTOR; STEROID; SULFOTRANSFERASE; SULT2A1 ENZYME; UNCLASSIFIED DRUG;

EID: 34548301080     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2007-0002     Document Type: Article
Times cited : (60)

References (44)
  • 1
    • 0035976638 scopus 로고    scopus 로고
    • Nuclear receptors and lipid physiology: Opening the X-files
    • Chawla A, Repa JJ, Evans RM, Mangelsdorf DJ 2001 Nuclear receptors and lipid physiology: opening the X-files. Science 294:1866-1870
    • (2001) Science , vol.294 , pp. 1866-1870
    • Chawla, A.1    Repa, J.J.2    Evans, R.M.3    Mangelsdorf, D.J.4
  • 2
    • 0036799870 scopus 로고    scopus 로고
    • The nuclear pregnane X receptor: A key regulator of xenobiotic metabolism
    • Kliewer SA, Goodwin B, Wilson TM 2002 The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. Endocr Rev 23:687-702
    • (2002) Endocr Rev , vol.23 , pp. 687-702
    • Kliewer, S.A.1    Goodwin, B.2    Wilson, T.M.3
  • 3
    • 23144447140 scopus 로고    scopus 로고
    • CAR, the continuously advancing receptor, in drug metabolism and disease
    • Qatanani M, Moore DD 2005 CAR, the continuously advancing receptor, in drug metabolism and disease. Curr Drug Metab 6:329-339
    • (2005) Curr Drug Metab , vol.6 , pp. 329-339
    • Qatanani, M.1    Moore, D.D.2
  • 4
    • 33745329809 scopus 로고    scopus 로고
    • The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification
    • Gachon F, Olela FF, Schaad O, Descombes P, Schibler U 2006 The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification. Cell Metab 4:25-36
    • (2006) Cell Metab , vol.4 , pp. 25-36
    • Gachon, F.1    Olela, F.F.2    Schaad, O.3    Descombes, P.4    Schibler, U.5
  • 7
    • 1342265781 scopus 로고    scopus 로고
    • DHEA-sulfotransferase is a target for transcriptional induction by the ligand activated vitamin D receptor
    • Echchgadda I, Song CS, Roy AK, Chatterjee B 2004 DHEA-sulfotransferase is a target for transcriptional induction by the ligand activated vitamin D receptor. Mol Pharmacol 65:720-729
    • (2004) Mol Pharmacol , vol.65 , pp. 720-729
    • Echchgadda, I.1    Song, C.S.2    Roy, A.K.3    Chatterjee, B.4
  • 8
    • 33646513294 scopus 로고    scopus 로고
    • Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds
    • Reschly EJ, Krasowski MD 2006 Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds. Curr Drug Metab 7:349-365
    • (2006) Curr Drug Metab , vol.7 , pp. 349-365
    • Reschly, E.J.1    Krasowski, M.D.2
  • 9
    • 33645401882 scopus 로고    scopus 로고
    • Song CS, Echchgadda I, Seo YK, Oh T, Kim S, Kim SA, Cho S, Shi L, Chatterjee B 2006 An essential role of the CAAT/enhancer binding protein-α in the vitamin D-induced expression of the human steroid/bile acid-sulfotransferase (SULT2A1). Mol Endocrinol [Erratum (2006) 20:1286] 20: 795-808
    • Song CS, Echchgadda I, Seo YK, Oh T, Kim S, Kim SA, Cho S, Shi L, Chatterjee B 2006 An essential role of the CAAT/enhancer binding protein-α in the vitamin D-induced expression of the human steroid/bile acid-sulfotransferase (SULT2A1). Mol Endocrinol [Erratum (2006) 20:1286] 20: 795-808
  • 10
    • 0037067665 scopus 로고    scopus 로고
    • Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes
    • Drocourt L, Ourlin JC, Pascussi JM, Maurel P, Vilarem MJ 2002 Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes. J Biol Chem 277:25125-25132
    • (2002) J Biol Chem , vol.277 , pp. 25125-25132
    • Drocourt, L.1    Ourlin, J.C.2    Pascussi, J.M.3    Maurel, P.4    Vilarem, M.J.5
  • 11
    • 0035141324 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4α (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis
    • Hayhurst GP, Lee YH, Lambert G, Ward JM, Gonzalez FJ 2001 Hepatocyte nuclear factor 4α (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis. Mol Cell Biol 21:1393-1403
    • (2001) Mol Cell Biol , vol.21 , pp. 1393-1403
    • Hayhurst, G.P.1    Lee, Y.H.2    Lambert, G.3    Ward, J.M.4    Gonzalez, F.J.5
  • 12
    • 0038241793 scopus 로고    scopus 로고
    • HNF4: A central regulator of hepatocyte differentiation and function
    • Watt AJ, Garrison WD, Duncan SA 2003 HNF4: a central regulator of hepatocyte differentiation and function. Hepatology 37:1249-1253
    • (2003) Hepatology , vol.37 , pp. 1249-1253
    • Watt, A.J.1    Garrison, W.D.2    Duncan, S.A.3
  • 14
    • 33748750262 scopus 로고    scopus 로고
    • Regulation of constitutive androstane receptor and its target genes by fasting, cyclic AMP, HNF-4α and the coactivator PGC-1 alpha
    • Ding X, Lichti K, Kim I, Gonzalez FJ, Staudinger JL 2006 Regulation of constitutive androstane receptor and its target genes by fasting, cyclic AMP, HNF-4α and the coactivator PGC-1 alpha. J Biol Chem 281:26540-26551
    • (2006) J Biol Chem , vol.281 , pp. 26540-26551
    • Ding, X.1    Lichti, K.2    Kim, I.3    Gonzalez, F.J.4    Staudinger, J.L.5
  • 15
    • 1942497956 scopus 로고    scopus 로고
    • Cytochromes P450, drugs, and diseases
    • Guengerich FP 2003 Cytochromes P450, drugs, and diseases. Mol Interv 3:194-204
    • (2003) Mol Interv , vol.3 , pp. 194-204
    • Guengerich, F.P.1
  • 16
    • 23944510035 scopus 로고    scopus 로고
    • The nuclear receptors constitutive androstane receptor and pregnane X receptor cross-talk with hepatic nuclear factor 4α to synergistically activate the human CYP2C9 promoter
    • Chen Y, Kissling G, Negishi M, Goldstein JA 2005 The nuclear receptors constitutive androstane receptor and pregnane X receptor cross-talk with hepatic nuclear factor 4α to synergistically activate the human CYP2C9 promoter. J Pharmacol Exp Ther 314:1125-1133
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 1125-1133
    • Chen, Y.1    Kissling, G.2    Negishi, M.3    Goldstein, J.A.4
  • 17
    • 0032705258 scopus 로고    scopus 로고
    • Regulation of rat hepatic hydroxysteroid sulfotransferase (SULT2-40/41) gene expression by glucocorticoids: Evidence for a dual mechanism of transcriptional control
    • Runge-Morris M, Wu W, Kocarek TA 1999 Regulation of rat hepatic hydroxysteroid sulfotransferase (SULT2-40/41) gene expression by glucocorticoids: evidence for a dual mechanism of transcriptional control. Mol Pharmacol 56:1198-1206
    • (1999) Mol Pharmacol , vol.56 , pp. 1198-1206
    • Runge-Morris, M.1    Wu, W.2    Kocarek, T.A.3
  • 19
    • 8344268492 scopus 로고    scopus 로고
    • Gene regulation for the senescence marker protein DHEA-sulfotransferase by the xenobiotic-activated nuclear pregnane X receptor (PXR)
    • Echchgadda I, Song CS, Oh TS, Cho SH, Rivera OJ, Chatterjee B 2004 Gene regulation for the senescence marker protein DHEA-sulfotransferase by the xenobiotic-activated nuclear pregnane X receptor (PXR). Mech Ageing Dev 125:733-745
    • (2004) Mech Ageing Dev , vol.125 , pp. 733-745
    • Echchgadda, I.1    Song, C.S.2    Oh, T.S.3    Cho, S.H.4    Rivera, O.J.5    Chatterjee, B.6
  • 21
    • 2442485772 scopus 로고    scopus 로고
    • The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction
    • Maglich JM, Watson, J McMillen PJ, Goodwin B, Willson TM, Moore JT 2004 The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction. J Biol Chem 279:19832-19838
    • (2004) J Biol Chem , vol.279 , pp. 19832-19838
    • Maglich, J.M.1    Watson, J.2    McMillen, P.J.3    Goodwin, B.4    Willson, T.M.5    Moore, J.T.6
  • 22
    • 30144431977 scopus 로고    scopus 로고
    • Vitamin D receptor regulation of steroid/bile acid sulfotransferase SULT2A1
    • Chatterjee B, Echchgadda I, Song CS 2005 Vitamin D receptor regulation of steroid/bile acid sulfotransferase SULT2A1. Methods Enzymol 400:165-191
    • (2005) Methods Enzymol , vol.400 , pp. 165-191
    • Chatterjee, B.1    Echchgadda, I.2    Song, C.S.3
  • 23
    • 23144433067 scopus 로고    scopus 로고
    • Regulation of sulfotransferases by xenobiotic receptors
    • Runge-Morris M, Kocarerk TA 2005 Regulation of sulfotransferases by xenobiotic receptors. Current Drug Metab 6:299-307
    • (2005) Current Drug Metab , vol.6 , pp. 299-307
    • Runge-Morris, M.1    Kocarerk, T.A.2
  • 24
    • 15744395646 scopus 로고    scopus 로고
    • Regulation of human hepatic hydroxysteroid sulfotransferase gene expression by the peroxisome proliferator-activated receptor α transcription factor
    • Fang HL, Strom SC, Cai H, Falany CN, Kocarek TA, Runge-Morris M 2005 Regulation of human hepatic hydroxysteroid sulfotransferase gene expression by the peroxisome proliferator-activated receptor α transcription factor. Mol Pharmacol 67:1257-1267
    • (2005) Mol Pharmacol , vol.67 , pp. 1257-1267
    • Fang, H.L.1    Strom, S.C.2    Cai, H.3    Falany, C.N.4    Kocarek, T.A.5    Runge-Morris, M.6
  • 26
    • 5044237671 scopus 로고    scopus 로고
    • Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR
    • Huang W, Zhang J, Wei P, Schrader WT, Moore DD 2004 Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR. Mol Endocrinol 18:2402-2408
    • (2004) Mol Endocrinol , vol.18 , pp. 2402-2408
    • Huang, W.1    Zhang, J.2    Wei, P.3    Schrader, W.T.4    Moore, D.D.5
  • 27
    • 0033999734 scopus 로고    scopus 로고
    • The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)] benzene is an agonist ligand for the nuclear receptor CAR
    • Tzameli I, Pissios P, Schuetz EG, Moore DD 2000 The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)] benzene is an agonist ligand for the nuclear receptor CAR. Mol Cell Biol 20:2951-2958
    • (2000) Mol Cell Biol , vol.20 , pp. 2951-2958
    • Tzameli, I.1    Pissios, P.2    Schuetz, E.G.3    Moore, D.D.4
  • 28
    • 2642544592 scopus 로고    scopus 로고
    • Estrogen receptor-α directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter
    • Métivier R, Penot G, Hübner MR, Reid G, Brand H, Koš M, Gannon F 2003 Estrogen receptor-α directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. Cell 115:751-763
    • (2003) Cell , vol.115 , pp. 751-763
    • Métivier, R.1    Penot, G.2    Hübner, M.R.3    Reid, G.4    Brand, H.5    Koš, M.6    Gannon, F.7
  • 29
    • 0032555487 scopus 로고    scopus 로고
    • Tissue-specific and androgen-repressible regulation of the rat dehydroepiandrosterone sulfotransferase gene promoter
    • Song CS, Jung MH, Kim SC, Hassan T, Roy AK, Chatterjee B 1998 Tissue-specific and androgen-repressible regulation of the rat dehydroepiandrosterone sulfotransferase gene promoter. J Biol Chem 273:21856-21866
    • (1998) J Biol Chem , vol.273 , pp. 21856-21866
    • Song, C.S.1    Jung, M.H.2    Kim, S.C.3    Hassan, T.4    Roy, A.K.5    Chatterjee, B.6
  • 30
    • 0028206388 scopus 로고
    • Major hydroxysteroid sulfotransferase STa in rat liver cytosol may consist of two microheterogeneous subunits
    • Ogura K, Satsukawa M, Okuda H, Hiratsuka A, Watabe T 1994 Major hydroxysteroid sulfotransferase STa in rat liver cytosol may consist of two microheterogeneous subunits. Chem Biol Interact 92:129-144
    • (1994) Chem Biol Interact , vol.92 , pp. 129-144
    • Ogura, K.1    Satsukawa, M.2    Okuda, H.3    Hiratsuka, A.4    Watabe, T.5
  • 31
    • 0028237799 scopus 로고
    • Molecular cloning of three sulfotransferase cDNAs from mouse liver
    • Kong AN, Fei P 1994 Molecular cloning of three sulfotransferase cDNAs from mouse liver. Chem Biol Interac 92:161-168
    • (1994) Chem Biol Interac , vol.92 , pp. 161-168
    • Kong, A.N.1    Fei, P.2
  • 33
    • 0030996250 scopus 로고    scopus 로고
    • Enzymology of human cytosolic sulfotransferases
    • Falany CN 1997 Enzymology of human cytosolic sulfotransferases. FASEB J 11:206-216
    • (1997) FASEB J , vol.11 , pp. 206-216
    • Falany, C.N.1
  • 34
    • 0036256351 scopus 로고    scopus 로고
    • Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors
    • Moore LB, Maglich JM, McKee DD, Wisely B, Willson TM, Kliewer SA, Lambert MH, Moore JT 2002 Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors. Mol Endocrinol 6:977-986
    • (2002) Mol Endocrinol , vol.6 , pp. 977-986
    • Moore, L.B.1    Maglich, J.M.2    McKee, D.D.3    Wisely, B.4    Willson, T.M.5    Kliewer, S.A.6    Lambert, M.H.7    Moore, J.T.8
  • 35
    • 0035834769 scopus 로고    scopus 로고
    • Dehydroepiandrosterone sulfotransferase gene induction by bile acid activated farnesoid X receptor
    • Song CS, Echchgadda I, Baek BS, Ahn SC, Oh T, Roy AK, Chatterjee B 2001 Dehydroepiandrosterone sulfotransferase gene induction by bile acid activated farnesoid X receptor. J Biol Chem 276:42549-42556
    • (2001) J Biol Chem , vol.276 , pp. 42549-42556
    • Song, C.S.1    Echchgadda, I.2    Baek, B.S.3    Ahn, S.C.4    Oh, T.5    Roy, A.K.6    Chatterjee, B.7
  • 36
    • 0022263551 scopus 로고
    • Rapid and selective inner ring deiodination of thyroxine sulfate by rat liver deiodinase
    • Mol JA, Visser TJ 1985 Rapid and selective inner ring deiodination of thyroxine sulfate by rat liver deiodinase. Endocrinol 117:8-12
    • (1985) Endocrinol , vol.117 , pp. 8-12
    • Mol, J.A.1    Visser, T.J.2
  • 37
    • 0033527343 scopus 로고    scopus 로고
    • Sulfation of iodothyronines by recombinant human liver steroid sulfotransferases
    • Li X, Anderson RJ 1999 Sulfation of iodothyronines by recombinant human liver steroid sulfotransferases. Biochim Biophys Res Commun 263:632-639
    • (1999) Biochim Biophys Res Commun , vol.263 , pp. 632-639
    • Li, X.1    Anderson, R.J.2
  • 38
    • 0015145941 scopus 로고
    • Bile acid sulfates. II. Formation, metabolism and excretion of lithocholic acid sulfates in the rat
    • Palmer RH 1971 Bile acid sulfates. II. Formation, metabolism and excretion of lithocholic acid sulfates in the rat. J Lipid Res 12:680-687
    • (1971) J Lipid Res , vol.12 , pp. 680-687
    • Palmer, R.H.1
  • 40
    • 0015993413 scopus 로고
    • Measurement of sulfated and nonsulfated bile acids in human serum and urine
    • Makino I, Shinozaki K, Nakagawa S, Mashimo K 1974 Measurement of sulfated and nonsulfated bile acids in human serum and urine. J Lipid Res 15:132-138
    • (1974) J Lipid Res , vol.15 , pp. 132-138
    • Makino, I.1    Shinozaki, K.2    Nakagawa, S.3    Mashimo, K.4
  • 41
    • 0031721571 scopus 로고    scopus 로고
    • Sulfation of α-hydroxytamoxifen catalyzed by human hydroxysteroid sulfotransferase results in tamoxifen-DNA adducts
    • Shibutani S, Shaw PM, Suzuki N, Dasaradhi L, Duffel MW, Terashima I 1998 Sulfation of α-hydroxytamoxifen catalyzed by human hydroxysteroid sulfotransferase results in tamoxifen-DNA adducts. Carcinogenesis 19:2007-2011
    • (1998) Carcinogenesis , vol.19 , pp. 2007-2011
    • Shibutani, S.1    Shaw, P.M.2    Suzuki, N.3    Dasaradhi, L.4    Duffel, M.W.5    Terashima, I.6
  • 42
    • 0036237854 scopus 로고    scopus 로고
    • Sulfation of budesonide by human cytosolic sulfotransferase, dehydroepiandrosterone- sulfotransferase (DHEA-ST)
    • Meloche CA, Sharma V, Swedmark S, Andersson P, Falany CN 2002 Sulfation of budesonide by human cytosolic sulfotransferase, dehydroepiandrosterone- sulfotransferase (DHEA-ST). Drug Metab Dispos 30:582-585
    • (2002) Drug Metab Dispos , vol.30 , pp. 582-585
    • Meloche, C.A.1    Sharma, V.2    Swedmark, S.3    Andersson, P.4    Falany, C.N.5
  • 43
    • 0037078917 scopus 로고    scopus 로고
    • Differential xenoestrogen-sulfating activities of the human cytosolic sulfotransferases: Molecular cloning, expression, and purification of human SULT2B1a and SULT2B1b sulfotransferases
    • Pai TG, Sugahara T, Suiko M, Sakakibara Y, Xu F, Liu MC 2002 Differential xenoestrogen-sulfating activities of the human cytosolic sulfotransferases: molecular cloning, expression, and purification of human SULT2B1a and SULT2B1b sulfotransferases. Biochim Biophys Acta 1573:165-170
    • (2002) Biochim Biophys Acta , vol.1573 , pp. 165-170
    • Pai, T.G.1    Sugahara, T.2    Suiko, M.3    Sakakibara, Y.4    Xu, F.5    Liu, M.C.6


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