Di(2-ethylhexyl) phthalate is a highly potent agonist for the human constitutive androstane receptor splice variant CAR2

Molecular Pharmacology

Volumn 75, Issue 5, 2009, Pages 1005-1012

  DeKeyser, Joshua G ^a   Stagliano, Michael C ^a,b   Auerbach, Scott S ^d   Prabhu, K Sandeep ^a   Jones, A Daniel ^b,c   Omiecinski, Curtis J ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b Michigan State University   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONSTITUTIVE ANDROSTANE RECEPTOR; CONSTITUTIVE ANDROSTANE RECEPTOR 1; CONSTITUTIVE ANDROSTANE RECEPTOR 2; CONSTITUTIVE ANDROSTANE RECEPTOR 3; CYTOCHROME P450 2B6; CYTOCHROME P450 3A4; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ARTICLE; CHILD; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE INSERTION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; LIGAND BINDING; LIVER CELL; LIVER PARENCHYMA; MALE; MARMOSET; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRESCHOOL CHILD; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; REPORTER GENE; TOXICITY; TRANSACTIVATION; TWO HYBRID SYSTEM;

AMINO ACID SEQUENCE; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BASE SEQUENCE; CALLITHRIX; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOCHROME P-450 CYP3A; DIETHYLHEXYL PHTHALATE; HEPATOCYTES; HUMANS; MICE; MOLECULAR SEQUENCE DATA; OXIDOREDUCTASES, N-DEMETHYLATING; PROTEIN ISOFORMS; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANSCRIPTION FACTORS;

EID: 64249112729     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.108.053702     Document Type: Article

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