Nuclear receptors as drug targets: New developments in coregulators, orphan receptors and major therapeutic areas

Expert Opinion on Therapeutic Targets

Volumn 7, Issue 5, 2003, Pages 679-684

  Sladek, Frances M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Bioinformatics; Cancer; Cofactors; Drug discovery; Human disease; Nuclear receptors (NRs); Partial agonists; Promoter selectivity; Structure activity relationship

Indexed keywords

20 EPICALCITRIOL; ANDROGEN RECEPTOR; ANTIDIABETIC AGENT; ANTIINFLAMMATORY AGENT; CELL NUCLEUS RECEPTOR; COLECALCIFEROL DERIVATIVE; COUMESTROL; CYCLOSPORIN; ESTRADIOL DERIVATIVE; ESTROGEN RECEPTOR; GC 1; HORMONE RECEPTOR STIMULATING AGENT; HYPERFORIN; KB 000141; MC 1627; MERCAPTOPURINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHENOBARBITAL; PLX 101203; PLX 101204; PREGNANE X RECEPTOR; PROGESTERONE RECEPTOR; RETINOIC ACID; RETINOID X RECEPTOR; RIFAMPICIN; SELECTIVE ESTROGEN RECEPTOR MODULATOR; THYROID HORMONE RECEPTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VITAMIN D RECEPTOR; VORINOSTAT;

CONFERENCE PAPER; CROHN DISEASE; DIABETES MELLITUS; DRUG RECEPTOR BINDING; DRUG TARGETING; FATIGUE; GASTROINTESTINAL SYMPTOM; GENE FUNCTION; GENE IDENTIFICATION; GENOMICS; HEART ARRHYTHMIA; HEART FAILURE; HUMAN; HUMAN GENOME; HYPERTENSION; LEUKEMIA; LIPOPHILICITY; LYMPHOMA; MASS SPECTROMETRY; MEDICAL INFORMATICS; MYOPATHY; OSTEOLYSIS; PROTEIN STRUCTURE; PROTEIN TARGETING; PROTEOMICS; ROBOTICS; SOLID TUMOR; STRUCTURE ANALYSIS; TACHYCARDIA; X RAY CRYSTALLOGRAPHY;

ANTINEOPLASTIC AGENTS; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; FORECASTING; GENE EXPRESSION REGULATION; HUMANS; LIGANDS; NEOPLASMS; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0141892590     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728222.7.5.679     Document Type: Conference Paper

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