-
1
-
-
84901295133
-
Deconstructing the peptide-MHC specificity of T cell recognition
-
Birnbaum ME, Mendoza JL, Sethi DK, Dong S, Glanville J, et al. 2014. Deconstructing the peptide-MHC specificity of T cell recognition. Cell 157:1073-87
-
(2014)
Cell
, vol.157
, pp. 1073-1087
-
-
Birnbaum, M.E.1
Mendoza, J.L.2
Sethi, D.K.3
Dong, S.4
Glanville, J.5
-
2
-
-
34247346627
-
How much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides?
-
Mazza C, Auphan-Anezin N, Gregoire C, Guimezanes A, Kellenberger C, et al. 2007. How much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides? EMBO J. 26:1972-83
-
(2007)
EMBO J.
, vol.26
, pp. 1972-1983
-
-
Mazza, C.1
Auphan-Anezin, N.2
Gregoire, C.3
Guimezanes, A.4
Kellenberger, C.5
-
3
-
-
0037304860
-
The formation and functions of the 21-and 23-kDa tyrosine-phosphorylated TCR ζ subunits
-
Pitcher LA, Young JA, Mathis MA, Wrage PC, Bartok B, van Oers NS. 2003. The formation and functions of the 21-and 23-kDa tyrosine-phosphorylated TCR ζ subunits. Immunol. Rev. 191:47-61
-
(2003)
Immunol. Rev.
, vol.191
, pp. 47-61
-
-
Pitcher, L.A.1
Young, J.A.2
Mathis, M.A.3
Wrage, P.C.4
Bartok, B.5
Van Oers, N.S.6
-
4
-
-
79958251745
-
T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse
-
Moran AE, Holzapfel KL, Xing Y, Cunningham NR, Maltzman JS, et al. 2011. T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse. J. Exp. Med. 208:1279-89
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1279-1289
-
-
Moran, A.E.1
Holzapfel, K.L.2
Xing, Y.3
Cunningham, N.R.4
Maltzman, J.S.5
-
5
-
-
77950524377
-
Dendritic cells control T cell tonic signaling required for responsiveness to foreign antigen
-
Hochweller K, Wabnitz GH, Samstag Y, Suffner J, Hammerling GJ, Garbi N. 2010. Dendritic cells control T cell tonic signaling required for responsiveness to foreign antigen. PNAS 107:5931-36
-
(2010)
PNAS
, vol.107
, pp. 5931-5936
-
-
Hochweller, K.1
Wabnitz, G.H.2
Samstag, Y.3
Suffner, J.4
Hammerling, G.J.5
Garbi, N.6
-
6
-
-
84887615587
-
A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4+ T cells
-
Huang J, Brameshuber M, Zeng X, Xie J, Li QJ, et al. 2013. A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4+ T cells. Immunity 39:846-57
-
(2013)
Immunity
, vol.39
, pp. 846-857
-
-
Huang, J.1
Brameshuber, M.2
Zeng, X.3
Xie, J.4
Li, Q.J.5
-
7
-
-
79959328071
-
T-cell triggering thresholds aremodulated by the number of antigen within individual T-cell receptor clusters
-
Manz BN, Jackson BL, Petit RS, Dustin ML,Groves J. 2011. T-cell triggering thresholds aremodulated by the number of antigen within individual T-cell receptor clusters. PNAS 108:9089-94
-
(2011)
PNAS
, vol.108
, pp. 9089-9094
-
-
Manz, B.N.1
Jackson, B.L.2
Petit, R.S.3
Dustin, M.L.4
Groves, J.5
-
8
-
-
84880089372
-
Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells
-
O'Donoghue GP, Pielak RM, Smoligovets AA, Lin JJ, Groves JT. 2013. Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells. eLIFE 2:e00778
-
(2013)
ELIFE
, vol.2
, pp. e00778
-
-
O'donoghue, G.P.1
Pielak, R.M.2
Smoligovets, A.A.3
Lin, J.J.4
Groves, J.T.5
-
9
-
-
23444457121
-
Early phosphorylation kinetics of proteins involved in proximal TCR-mediated signaling pathways
-
Houtman JC, Houghtling RA, Barda-Saad M, Toda Y, Samelson LE. 2005. Early phosphorylation kinetics of proteins involved in proximal TCR-mediated signaling pathways. J. Immunol. 175:2449-58
-
(2005)
J. Immunol.
, vol.175
, pp. 2449-2458
-
-
Houtman, J.C.1
Houghtling, R.A.2
Barda-Saad, M.3
Toda, Y.4
Samelson, L.E.5
-
10
-
-
34447647655
-
Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist
-
Huse M, Klein LO, Girvin AT, Faraj JM, Li QJ, et al. 2007. Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist. Immunity 27:76-88
-
(2007)
Immunity
, vol.27
, pp. 76-88
-
-
Huse, M.1
Klein, L.O.2
Girvin, A.T.3
Faraj, J.M.4
Li, Q.J.5
-
11
-
-
84883417144
-
T lymphocytes sense antigens within seconds and make a decision within one minute
-
Brodovitch A, Bongrand P, Pierres A. 2013. T lymphocytes sense antigens within seconds and make a decision within one minute. J. Immunol. 191:2064-71
-
(2013)
J. Immunol.
, vol.191
, pp. 2064-2071
-
-
Brodovitch, A.1
Bongrand, P.2
Pierres, A.3
-
13
-
-
0037306046
-
An evolutionary and structural perspective on T cell antigen receptor function
-
Malissen B. 2003. An evolutionary and structural perspective on T cell antigen receptor function. Immunol. Rev. 191:7-27
-
(2003)
Immunol. Rev.
, vol.191
, pp. 7-27
-
-
Malissen, B.1
-
14
-
-
84900432315
-
Mechanism of activation of protein kinase JAK2 by the growth hormone receptor
-
Brooks AJ, DaiW, O'MaraML, AbankwaD, Chhabra Y, et al. 2014. Mechanism of activation of protein kinase JAK2 by the growth hormone receptor. Science 344:1249783
-
(2014)
Science
, vol.344
, pp. 1249783
-
-
Brooks, A.J.1
Dai, W.2
O'mara, M.L.3
Abankwa, D.4
Chhabra, Y.5
-
15
-
-
79959542722
-
The CD3 subunit contains a phosphoinositide-binding motif that is required for the stable accumulation of TCR-CD3 complex at the immunological synapse
-
DeFord-Watts LM, Dougall DS, Belkaya S, Johnson BA, Eitson JL, et al. 2011. The CD3 subunit contains a phosphoinositide-binding motif that is required for the stable accumulation of TCR-CD3 complex at the immunological synapse. J. Immunol. 186:6839-47
-
(2011)
J. Immunol.
, vol.186
, pp. 6839-6847
-
-
Deford-Watts, L.M.1
Dougall, D.S.2
Belkaya, S.3
Johnson, B.A.4
Eitson, J.L.5
-
16
-
-
55449138409
-
Regulation of T cell receptor activation by dynamic membrane binding of the CD3ε cytoplasmic tyrosine-based motif
-
Xu C, Gagnon E, Call ME, Schnell JR, Schwieters CD, et al. 2008. Regulation of T cell receptor activation by dynamic membrane binding of the CD3ε cytoplasmic tyrosine-based motif. Cell 135:702-13
-
(2008)
Cell
, vol.135
, pp. 702-713
-
-
Xu, C.1
Gagnon, E.2
Call, M.E.3
Schnell, J.R.4
Schwieters, C.D.5
-
17
-
-
84903639556
-
Membrane association of the CD3ε signaling domain is required for optimal T cell development and function
-
Bettini ML, Guy C, Dash P, Vignali KM, Hamm DE, et al. 2014. Membrane association of the CD3ε signaling domain is required for optimal T cell development and function. J. Immunol. 193:258-67
-
(2014)
J. Immunol.
, vol.193
, pp. 258-267
-
-
Bettini, M.L.1
Guy, C.2
Dash, P.3
Vignali, K.M.4
Hamm, D.E.5
-
18
-
-
0033762433
-
Phosphorylation of T cell receptor is regulated by a lipid dependent folding transition
-
Aivazian D, Stern LJ. 2000. Phosphorylation of T cell receptor is regulated by a lipid dependent folding transition. Nat. Struct. Biol. 7:1023-26
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 1023-1026
-
-
Aivazian, D.1
Stern, L.J.2
-
19
-
-
0037188899
-
Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential forTcell receptor signaling and synapse formation
-
Gil D, Schamel WW, Montoya M, Sanchez-Madrid F, Alarcon B. 2002. Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential forTcell receptor signaling and synapse formation. Cell 109:901-12
-
(2002)
Cell
, vol.109
, pp. 901-912
-
-
Gil, D.1
Schamel, W.W.2
Montoya, M.3
Sanchez-Madrid, F.4
Alarcon, B.5
-
20
-
-
21244489949
-
The CD3ε proline-rich sequence, and its interaction with Nck, is not required for T cell development and function
-
Szymczak AL, Workman CJ, Gil D, Dilioglou S, Vignali KM, et al. 2005. The CD3ε proline-rich sequence, and its interaction with Nck, is not required for T cell development and function. J. Immunol. 175:270-75
-
(2005)
J. Immunol.
, vol.175
, pp. 270-275
-
-
Szymczak, A.L.1
Workman, C.J.2
Gil, D.3
Dilioglou, S.4
Vignali, K.M.5
-
21
-
-
42449149487
-
The proline-rich sequence of CD3εcontrols T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes
-
Mingueneau M, SansoniA,Gregoire C, Roncagalli R, Aguado E, et al. 2008. The proline-rich sequence of CD3εcontrols T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes. Nat. Immunol. 9:522-32
-
(2008)
Nat. Immunol.
, vol.9
, pp. 522-532
-
-
Mingueneau, M.1
Sansoni, A.2
Gregoire, C.3
Roncagalli, R.4
Aguado, E.5
-
22
-
-
82755165363
-
Basic residues in the T-cell receptor cytoplasmic domain mediate membrane association and modulate signaling
-
Zhang H, Cordoba SP, Dushek O, van der Merwe PA. 2011. Basic residues in the T-cell receptor cytoplasmic domain mediate membrane association and modulate signaling. PNAS 108:19323-28
-
(2011)
PNAS
, vol.108
, pp. 19323-19328
-
-
Zhang, H.1
Cordoba, S.P.2
Dushek, O.3
Van Der Merwe, P.A.4
-
23
-
-
77956167214
-
What controls T cell receptor phosphorylation?
-
Fernandes RA, Yu C, Carmo AM, Evans EJ, van der Merwe PA, Davis SJ. 2010. What controls T cell receptor phosphorylation? Cell 142:668-69
-
(2010)
Cell
, vol.142
, pp. 668-669
-
-
Fernandes, R.A.1
Yu, C.2
Carmo, A.M.3
Evans, E.J.4
Van Der Merwe, P.A.5
Davis, S.J.6
-
24
-
-
23744479535
-
How the T cell receptor sees antigen- A structural view
-
Garcia KC, Adams EJ. 2005. How the T cell receptor sees antigen- A structural view. Cell 122:333-36
-
(2005)
Cell
, vol.122
, pp. 333-336
-
-
Garcia, K.C.1
Adams, E.J.2
-
25
-
-
84877669593
-
The basic principles of chimeric antigen receptor design
-
Sadelain M, Brentjens R, Riviere I. 2013. The basic principles of chimeric antigen receptor design. Cancer Discov. 3:388-98
-
(2013)
Cancer Discov.
, vol.3
, pp. 388-398
-
-
Sadelain, M.1
Brentjens, R.2
Riviere, I.3
-
26
-
-
84864221004
-
A new era of GPCR structural and chemical biology
-
Granier S, Kobilka B. 2012. A new era of GPCR structural and chemical biology. Nat. Chem. Biol. 8:670-73
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 670-673
-
-
Granier, S.1
Kobilka, B.2
-
27
-
-
1942540796
-
Supine orientation of a murine MHC class i molecule on the membrane bilayer
-
Mitra AK, Celia H, Ren G, Luz JG, Wilson IA, Teyton L. 2004. Supine orientation of a murine MHC class I molecule on the membrane bilayer. Curr. Biol. 14:718-24
-
(2004)
Curr. Biol.
, vol.14
, pp. 718-724
-
-
Mitra, A.K.1
Celia, H.2
Ren, G.3
Luz, J.G.4
Wilson, I.A.5
Teyton, L.6
-
28
-
-
84916613807
-
Molecular architecture of the αβT cell receptor-CD3 complex
-
Birnbaum ME, Berry R, Hsiao YS, Chen Z, Shingu-VazquezMA, et al. 2014. Molecular architecture of the αβT cell receptor-CD3 complex. PNAS 111:17576-81
-
(2014)
PNAS
, vol.111
, pp. 17576-17581
-
-
Birnbaum, M.E.1
Berry, R.2
Hsiao, Y.S.3
Chen, Z.4
Shingu-Vazquez, M.A.5
-
29
-
-
0025182959
-
Adhesion receptors of the immune system
-
Springer TA. 1990. Adhesion receptors of the immune system. Nature 346:425-34
-
(1990)
Nature
, vol.346
, pp. 425-434
-
-
Springer, T.A.1
-
30
-
-
84859470532
-
Crystal structure of a complete ternary complex ofT-cell receptor, peptide-MHC, and CD4
-
Yin Y,Wang XX, Mariuzza RA. 2012. Crystal structure of a complete ternary complex ofT-cell receptor, peptide-MHC, and CD4. PNAS 109:5405-10
-
(2012)
PNAS
, vol.109
, pp. 5405-5410
-
-
Yin, Y.1
Wang, X.X.2
Mariuzza, R.A.3
-
31
-
-
0030581710
-
Immunology. Two faces are better than one
-
Malissen B. 1996. Immunology. Two faces are better than one. Nature 384:518-19
-
(1996)
Nature
, vol.384
, pp. 518-519
-
-
Malissen, B.1
-
32
-
-
77953911933
-
Constitutively active Lck kinase in T cells drives antigen receptor signal transduction
-
Nika K, Soldani C, Salek M, Paster W, Gray A, et al. 2010. Constitutively active Lck kinase in T cells drives antigen receptor signal transduction. Immunity 32:766-77
-
(2010)
Immunity
, vol.32
, pp. 766-777
-
-
Nika, K.1
Soldani, C.2
Salek, M.3
Paster, W.4
Gray, A.5
-
33
-
-
0032968708
-
The dynamics of T cell receptor signaling: Complex orchestration and the key roles of tempo and cooperation
-
Germain RN, Stefanova I. 1999. The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation. Annu. Rev. Immunol. 17:467-522
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 467-522
-
-
Germain, R.N.1
Stefanova, I.2
-
34
-
-
84915754505
-
Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance
-
Stepanek O, Prabhakar AS, Osswald C, King CG, Bulek A, et al. 2014. Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance. Cell 159:333-45
-
(2014)
Cell
, vol.159
, pp. 333-345
-
-
Stepanek, O.1
Prabhakar, A.S.2
Osswald, C.3
King, C.G.4
Bulek, A.5
-
35
-
-
0031028629
-
The single positive T cells found in CD3-ζ/η -/- mice overtly react with self-major histocompatibility complex molecules upon restoration of normal surface density of T cell receptor-CD3 complex
-
Lin SY, Ardouin L, Gillet A, Malissen M, Malissen B. 1997. The single positive T cells found in CD3-ζ/η -/- mice overtly react with self-major histocompatibility complex molecules upon restoration of normal surface density of T cell receptor-CD3 complex. J. Exp. Med. 185:707-15
-
(1997)
J. Exp. Med.
, vol.185
, pp. 707-715
-
-
Lin, S.Y.1
Ardouin, L.2
Gillet, A.3
Malissen, M.4
Malissen, B.5
-
36
-
-
0037077094
-
Induction of T helper type 2 immunity by a point mutation in the LAT adaptor
-
Aguado E, Richelme S, Nunez-Cruz S, Miazek A, Mura A-M, et al. 2002. Induction of T helper type 2 immunity by a point mutation in the LAT adaptor. Science 296:2036-40
-
(2002)
Science
, vol.296
, pp. 2036-2040
-
-
Aguado, E.1
Richelme, S.2
Nunez-Cruz, S.3
Miazek, A.4
Mura, A.-M.5
-
37
-
-
0028902752
-
Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists
-
Madrenas J, Wange RL, Wang JL, Isakov N, Samelson LE, Germain RN. 1995. Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists. Science 267:515-18
-
(1995)
Science
, vol.267
, pp. 515-518
-
-
Madrenas, J.1
Wange, R.L.2
Wang, J.L.3
Isakov, N.4
Samelson, L.E.5
Germain, R.N.6
-
38
-
-
84878999914
-
Structural basis for activation of ZAP-70 by phosphorylation of the SH2-kinase linker
-
Yan Q, Barros T, Visperas PR, Deindl S, Kadlecek TA, et al. 2013. Structural basis for activation of ZAP-70 by phosphorylation of the SH2-kinase linker. Mol. Cell. Biol. 33:2188-201
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 2188-2201
-
-
Yan, Q.1
Barros, T.2
Visperas, P.R.3
Deindl, S.4
Kadlecek, T.A.5
-
39
-
-
84906241799
-
Insights into the initiation ofTCRsignaling
-
Chakraborty AK,Weiss A. 2014. Insights into the initiation ofTCRsignaling. Nat. Immunol. 15:798-807
-
(2014)
Nat. Immunol.
, vol.15
, pp. 798-807
-
-
Chakraborty, A.K.1
Weiss, A.2
-
40
-
-
0031229746
-
The Lck SH2 phosphotyrosine binding site is critical for efficient TCR-induced processive tyrosine phosphorylation of the zeta-chain and IL-2 production
-
Lewis LA, Chung CD, Chen J, Parnes JR,Moran M, et al. 1997. The Lck SH2 phosphotyrosine binding site is critical for efficient TCR-induced processive tyrosine phosphorylation of the zeta-chain and IL-2 production. J. Immunol. 159:2292-300
-
(1997)
J. Immunol.
, vol.159
, pp. 2292-2300
-
-
Lewis, L.A.1
Chung, C.D.2
Chen, J.3
Parnes, J.R.4
Moran, M.5
-
41
-
-
84891836984
-
Locking the active conformation of c-SRC kinase through the phosphorylation of the activation loop
-
Meng Y, Roux B. 2014. Locking the active conformation of c-SRC kinase through the phosphorylation of the activation loop. J. Mol. Biol. 426:423-35
-
(2014)
J. Mol. Biol.
, vol.426
, pp. 423-435
-
-
Meng, Y.1
Roux, B.2
-
42
-
-
0032445491
-
CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity
-
Azzam HS,Grinberg A, Lui K, ShenH, Shores EW, Love PE. 1998. CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity. J. Exp. Med. 188:2301-11
-
(1998)
J. Exp. Med.
, vol.188
, pp. 2301-2311
-
-
Azzam, H.S.1
Grinberg, A.2
Lui, K.3
Shen, H.4
Shores, E.W.5
Love, P.E.6
-
43
-
-
84874244135
-
T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens
-
Mandl JN, Monteiro JP, Vrisekoop N, Germain RN. 2013. T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens. Immunity 38:263-74
-
(2013)
Immunity
, vol.38
, pp. 263-274
-
-
Mandl, J.N.1
Monteiro, J.P.2
Vrisekoop, N.3
Germain, R.N.4
-
44
-
-
84924979971
-
The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8 T cells to respond to foreign antigens
-
Fulton RB, Hamilton SE, Xing Y, Best JA, Goldrath AW, et al. 2014. The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8 T cells to respond to foreign antigens. Nat. Immunol. 16:107-17
-
(2014)
Nat. Immunol.
, vol.16
, pp. 107-117
-
-
Fulton, R.B.1
Hamilton, S.E.2
Xing, Y.3
Best, J.A.4
Goldrath, A.W.5
-
45
-
-
84906243997
-
The self-obsession of T cells: How TCR signaling thresholds affect fate 'decisions' and effector function
-
Hogquist KA, Jameson SC. 2014. The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function. Nat. Immunol. 15:815-23
-
(2014)
Nat. Immunol.
, vol.15
, pp. 815-823
-
-
Hogquist, K.A.1
Jameson, S.C.2
-
46
-
-
84894447120
-
Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC
-
Persaud SP, Parker CR, Lo WL, Weber KS, Allen PM. 2014. Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC. Nat. Immunol. 15:266-74
-
(2014)
Nat. Immunol.
, vol.15
, pp. 266-274
-
-
Persaud, S.P.1
Parker, C.R.2
Lo, W.L.3
Weber, K.S.4
Allen, P.M.5
-
47
-
-
27844541328
-
Modeling T cell antigen discrimination based on feedback control of digital ERK responses
-
Altan-Bonnet G, Germain RN. 2005. Modeling T cell antigen discrimination based on feedback control of digital ERK responses. PLOS Biol. 3:e356
-
(2005)
PLOS Biol.
, vol.3
, pp. e356
-
-
Altan-Bonnet, G.1
Germain, R.N.2
-
48
-
-
84857415635
-
Constitutive type i interferon modulates homeostatic balance through tonic signaling
-
Gough DJ, Messina NL, Clarke CJ, Johnstone RW, Levy DE. 2012. Constitutive type I interferon modulates homeostatic balance through tonic signaling. Immunity 36:166-74
-
(2012)
Immunity
, vol.36
, pp. 166-174
-
-
Gough, D.J.1
Messina, N.L.2
Clarke, C.J.3
Johnstone, R.W.4
Levy, D.E.5
-
49
-
-
62249131518
-
Complete but curtailed T-cell response to very low-affinity antigen
-
Zehn D, Lee SY, Bevan MJ. 2009. Complete but curtailed T-cell response to very low-affinity antigen. Nature 458:211-14
-
(2009)
Nature
, vol.458
, pp. 211-214
-
-
Zehn, D.1
Lee, S.Y.2
Bevan, M.J.3
-
50
-
-
84897458111
-
An induced rebinding model of antigen discrimination
-
Dushek O, van der Merwe PA. 2014. An induced rebinding model of antigen discrimination. Trends Immunol. 35:153-58
-
(2014)
Trends Immunol.
, vol.35
, pp. 153-158
-
-
Dushek, O.1
Van Der Merwe, P.A.2
-
51
-
-
34848898406
-
Quantitative challenges in understanding ligand discrimination by αβT cells
-
Feinerman O, Germain RN, Altan-Bonnet G. 2008. Quantitative challenges in understanding ligand discrimination by αβT cells. Mol. Immunol. 45:619-31
-
(2008)
Mol. Immunol.
, vol.45
, pp. 619-631
-
-
Feinerman, O.1
Germain, R.N.2
Altan-Bonnet, G.3
-
53
-
-
38349177876
-
What is the biological relevance of the specific bond properties revealed by single-molecule studies?
-
Robert P, Benoliel AM, Pierres A, Bongrand P. 2007. What is the biological relevance of the specific bond properties revealed by single-molecule studies? J. Mol. Recognit. 20:432-47
-
(2007)
J. Mol. Recognit.
, vol.20
, pp. 432-447
-
-
Robert, P.1
Benoliel, A.M.2
Pierres, A.3
Bongrand, P.4
-
54
-
-
0035970109
-
Selectin receptor-ligand bonds: Formation limited by shear rate and dissociation governed by the Bell model
-
Chen S, Springer TA. 2001. Selectin receptor-ligand bonds: formation limited by shear rate and dissociation governed by the Bell model. PNAS 98:950-55
-
(2001)
PNAS
, vol.98
, pp. 950-955
-
-
Chen, S.1
Springer, T.A.2
-
55
-
-
84898644308
-
Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling
-
Liu B, Chen W, Evavold BD, Zhu C. 2014. Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling. Cell 157:357-68
-
(2014)
Cell
, vol.157
, pp. 357-368
-
-
Liu, B.1
Chen, W.2
Evavold, B.D.3
Zhu, C.4
-
56
-
-
0037653696
-
Direct observation of catch bonds involving cell-adhesion molecules
-
Marshall BT, LongM, Piper JW, Yago T,McEver RP, Zhu C. 2003. Direct observation of catch bonds involving cell-adhesion molecules. Nature 423:190-93
-
(2003)
Nature
, vol.423
, pp. 190-193
-
-
Marshall, B.T.1
Long, M.2
Piper, J.W.3
Yago, T.4
McEver, R.P.5
Zhu, C.6
-
57
-
-
33847780609
-
A structure-based sliding-rebindingmechanism for catch bonds
-
Lou J, ZhuC. 2007. A structure-based sliding-rebindingmechanism for catch bonds. Biophys. J. 92:1471-85
-
(2007)
Biophys. J.
, vol.92
, pp. 1471-1485
-
-
Lou, J.1
Zhu, C.2
-
58
-
-
80054687448
-
The two-pathway model of the biological catch-bond as a limit of the allosteric model
-
Pereverzev YV, Prezhdo E, Sokurenko EV. 2011. The two-pathway model of the biological catch-bond as a limit of the allosteric model. Biophys. J. 101:2026-36
-
(2011)
Biophys. J.
, vol.101
, pp. 2026-2036
-
-
Pereverzev, Y.V.1
Prezhdo, E.2
Sokurenko, E.V.3
-
59
-
-
84869223932
-
Ideal, catch, and slip bonds in cadherin adhesion
-
Rakshit S, Zhang Y, Manibog K, Shafraz O, Sivasankar S. 2012. Ideal, catch, and slip bonds in cadherin adhesion. PNAS 109:18815-20
-
(2012)
PNAS
, vol.109
, pp. 18815-18820
-
-
Rakshit, S.1
Zhang, Y.2
Manibog, K.3
Shafraz, O.4
Sivasankar, S.5
-
60
-
-
28444492383
-
The solution to the streptavidin-biotin paradox: The influence of history on the strength of single molecular bonds
-
Pincet F, Husson J. 2005. The solution to the streptavidin-biotin paradox: the influence of history on the strength of single molecular bonds. Biophys. J. 89:4374-81
-
(2005)
Biophys. J.
, vol.89
, pp. 4374-4381
-
-
Pincet, F.1
Husson, J.2
-
61
-
-
21244479320
-
Force history dependence of receptorligand dissociation
-
Marshall BT, Sarangapani KK, Lou J, McEver RP, Zhu C. 2005. Force history dependence of receptorligand dissociation. Biophys. J. 88:1458-66
-
(2005)
Biophys. J.
, vol.88
, pp. 1458-1466
-
-
Marshall, B.T.1
Sarangapani, K.K.2
Lou, J.3
McEver, R.P.4
Zhu, C.5
-
62
-
-
84866369099
-
Quantitative modeling assesses the contribution of bond strengthening, rebinding and force sharing to the avidity of biomolecule interactions
-
Lo Schiavo V, Robert P, Limozin L, Bongrand P. 2012. Quantitative modeling assesses the contribution of bond strengthening, rebinding and force sharing to the avidity of biomolecule interactions. PLOS ONE 7:e44070
-
(2012)
PLOS ONE
, vol.7
, pp. e44070
-
-
Lo Schiavo, V.1
Robert, P.2
Limozin, L.3
Bongrand, P.4
-
63
-
-
0029332175
-
Influence of surface charges on cell adhesion: Difference between static and dynamic conditions
-
Sabri S, Pierres A, Benoliel AM, Bongrand P. 1995. Influence of surface charges on cell adhesion: difference between static and dynamic conditions. Biochem. Cell Biol. 73:411-20
-
(1995)
Biochem. Cell Biol.
, vol.73
, pp. 411-420
-
-
Sabri, S.1
Pierres, A.2
Benoliel, A.M.3
Bongrand, P.4
-
64
-
-
77249114784
-
TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity
-
Huppa JB, Axmann M, Mortelmaier MA, Lillemeier BF, Newell EW, et al. 2010. TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity. Nature 463:963-67
-
(2010)
Nature
, vol.463
, pp. 963-967
-
-
Huppa, J.B.1
Axmann, M.2
Mortelmaier, M.A.3
Lillemeier, B.F.4
Newell, E.W.5
-
65
-
-
77950809538
-
The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness
-
Huang J, Zarnitsyna VI, Liu B, Edwards LJ, Jiang N, et al. 2010. The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness. Nature 464:932-36
-
(2010)
Nature
, vol.464
, pp. 932-936
-
-
Huang, J.1
Zarnitsyna, V.I.2
Liu, B.3
Edwards, L.J.4
Jiang, N.5
-
66
-
-
0000359208
-
Kinetic proofreading: A new mechanism for reducing errors in biosynthetic processes requiring high specificity
-
Hopfield JJ. 1974. Kinetic proofreading: a new mechanism for reducing errors in biosynthetic processes requiring high specificity. PNAS 71:4135-39
-
(1974)
PNAS
, vol.71
, pp. 4135-4139
-
-
Hopfield, J.J.1
-
67
-
-
0029063148
-
Kinetic proofreading in T-cell receptor signal transduction
-
McKeithan TW. 1995. Kinetic proofreading in T-cell receptor signal transduction. PNAS 92:5042-46
-
(1995)
PNAS
, vol.92
, pp. 5042-5046
-
-
McKeithan, T.W.1
-
68
-
-
27744588266
-
Understanding specificity and sensitivity of T-cell recognition
-
George AJ, Stark J, Chan C. 2005. Understanding specificity and sensitivity of T-cell recognition. Trends Immunol. 26:653-59
-
(2005)
Trends Immunol.
, vol.26
, pp. 653-659
-
-
George, A.J.1
Stark, J.2
Chan, C.3
-
69
-
-
73449105773
-
A role for rebinding in rapid and reliableTcell responses to antigen
-
Dushek O, Das R,Coombs D. 2009. A role for rebinding in rapid and reliableTcell responses to antigen. PLOS Comput. Biol. 5:e1000578
-
(2009)
PLOS Comput. Biol.
, vol.5
, pp. e1000578
-
-
Dushek, O.1
Das, R.2
Coombs, D.3
-
70
-
-
84874137801
-
Membrane dynamics shape TCR-generated signaling
-
He HT, Bongrand P. 2012. Membrane dynamics shape TCR-generated signaling. Front. Immunol. 3:90
-
(2012)
Front. Immunol.
, vol.3
, pp. 90
-
-
He, H.T.1
Bongrand, P.2
-
71
-
-
84876376859
-
Improved ligand discrimination by force-induced unbinding of the T cell receptor from peptide-MHC
-
Klotzsch E, Schutz GJ. 2013. Improved ligand discrimination by force-induced unbinding of the T cell receptor from peptide-MHC. Biophys. J. 104:1670-75
-
(2013)
Biophys. J.
, vol.104
, pp. 1670-1675
-
-
Klotzsch, E.1
Schutz, G.J.2
-
73
-
-
33746255935
-
Lateral membrane waves constitute a universal dynamic pattern of motile cells
-
Dobereiner HG, Dubin-Thaler BJ, Hofman JM, Xenias HS, Sims TN, et al. 2006. Lateral membrane waves constitute a universal dynamic pattern of motile cells. Phys. Rev. Lett. 97:038102
-
(2006)
Phys. Rev. Lett.
, vol.97
, pp. 038102
-
-
Dobereiner, H.G.1
Dubin-Thaler, B.J.2
Hofman, J.M.3
Xenias, H.S.4
Sims, T.N.5
-
75
-
-
33144457671
-
Brownian motion of nucleated cell envelopes impedes adhesion
-
Zidovska A, Sackmann E. 2006. Brownian motion of nucleated cell envelopes impedes adhesion. Phys. Rev. Lett. 96:048103
-
(2006)
Phys. Rev. Lett.
, vol.96
, pp. 048103
-
-
Zidovska, A.1
Sackmann, E.2
-
76
-
-
84925503759
-
Use of TIRF to monitor T-lymphocyte membrane dynamics with submicrometer and subsecond resolution
-
In press
-
Brodovitch A, Limozin L, Bongrand P, Pierres A. 2014. Use of TIRF to monitor T-lymphocyte membrane dynamics with submicrometer and subsecond resolution. Cell. Mol. Bioeng. In press. doi: 10.1007/s12195-014-0361-8
-
(2014)
Cell. Mol. Bioeng.
-
-
Brodovitch, A.1
Limozin, L.2
Bongrand, P.3
Pierres, A.4
-
77
-
-
84893837202
-
CD28 and CD3 have complementary roles in T-cell traction forces
-
Bashour KT, Gondarenko A, Chen H, Shen K, Liu X, et al. 2014. CD28 and CD3 have complementary roles in T-cell traction forces. PNAS 111:2241-46
-
(2014)
PNAS
, vol.111
, pp. 2241-2246
-
-
Bashour, K.T.1
Gondarenko, A.2
Chen, H.3
Shen, K.4
Liu, X.5
-
78
-
-
79955904928
-
Force generation upon T cell receptor engagement
-
Husson J, Chemin K, Bohineust A, Hivroz C, Henry N. 2011. Force generation upon T cell receptor engagement. PLOS ONE 6:e19680
-
(2011)
PLOS ONE
, vol.6
, pp. e19680
-
-
Husson, J.1
Chemin, K.2
Bohineust, A.3
Hivroz, C.4
Henry, N.5
-
79
-
-
71449090489
-
TheαβTcell receptor is an anisotropic mechanosensor
-
Kim ST, Takeuchi K, SunZY, ToumaM,CastroCE, et al. 2009. TheαβTcell receptor is an anisotropic mechanosensor. J. Biol. Chem. 284:31028-37
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 31028-31037
-
-
Kim, S.T.1
Takeuchi, K.2
Sun, Z.Y.3
Touma, M.4
Castro, C.E.5
-
80
-
-
77953473256
-
Cutting edge: Mechanical forces acting on T cells immobilized via the TCR complex can trigger TCR signaling
-
Li YC, Chen BM, Wu PC, Cheng TL, Kao LS, et al. 2010. Cutting edge: Mechanical forces acting on T cells immobilized via the TCR complex can trigger TCR signaling. J. Immunol. 184:5959-63
-
(2010)
J. Immunol.
, vol.184
, pp. 5959-5963
-
-
Li, Y.C.1
Chen, B.M.2
Wu, P.C.3
Cheng, T.L.4
Kao, L.S.5
-
82
-
-
42049101786
-
The receptor deformation model of TCR triggering
-
Ma Z, Janmey PA, Finkel TH. 2008. The receptor deformation model of TCR triggering. FASEB J. 22:1002-8
-
(2008)
FASEB J.
, vol.22
, pp. 1002-1008
-
-
Ma, Z.1
Janmey, P.A.2
Finkel, T.H.3
-
83
-
-
84862978540
-
TCR mechanobiology: Torques and tunable structures linked to early T cell signaling
-
Kim ST, Shin Y, Brazin K, Mallis RJ, Sun ZY, et al. 2012. TCR mechanobiology: torques and tunable structures linked to early T cell signaling. Front. Immunol. 3:76
-
(2012)
Front. Immunol.
, vol.3
, pp. 76
-
-
Kim, S.T.1
Shin, Y.2
Brazin, K.3
Mallis, R.J.4
Sun, Z.Y.5
-
84
-
-
0025655401
-
Localization of calcium and microfilament changes in mechanically stressed cells
-
HoroyanM,BenolielAM,Capo C, Bongrand P. 1990. Localization of calcium and microfilament changes in mechanically stressed cells. Cell Biophys. 17:243-56. http://www.hal.inserm.fr/inserm-00401740/fr/
-
(1990)
Cell Biophys.
, vol.17
, pp. 243-256
-
-
Horoyan, M.1
Benoliel, A.M.2
Capo, C.3
Bongrand, P.4
-
85
-
-
77954486800
-
Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics
-
Grashoff C, Hoffman BD, BrennerMD, Zhou R, ParsonsM, et al. 2010. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature 466:263-66
-
(2010)
Nature
, vol.466
, pp. 263-266
-
-
Grashoff, C.1
Hoffman, B.D.2
Brenner, M.D.3
Zhou, R.4
Parsons, M.5
-
86
-
-
59149094538
-
Stretching single talin rod molecules activates vinculin binding
-
del Rio A, Perez-Jimenez R, Liu R, Roca-Cusachs P, Fernandez JM, SheetzMP. 2009. Stretching single talin rod molecules activates vinculin binding. Science 323:638-41
-
(2009)
Science
, vol.323
, pp. 638-641
-
-
Del Rio, A.1
Perez-Jimenez, R.2
Liu, R.3
Roca-Cusachs, P.4
Fernandez, J.M.5
Sheetz, M.P.6
-
87
-
-
84856004728
-
Mechanosensing in T lymphocyte activation
-
Judokusumo E, Tabdanov E, Kumari S, DustinML, Kam LC. 2012. Mechanosensing in T lymphocyte activation. Biophys. J. 102:L5-7
-
(2012)
Biophys. J.
, vol.102
, pp. L5-7
-
-
Judokusumo, E.1
Tabdanov, E.2
Kumari, S.3
Dustin, M.L.4
Kam, L.C.5
-
88
-
-
79959397904
-
Mechanisms of membrane curvature sensing
-
Antonny B. 2011. Mechanisms of membrane curvature sensing. Annu. Rev. Biochem. 80:101-23
-
(2011)
Annu. Rev. Biochem.
, vol.80
, pp. 101-123
-
-
Antonny, B.1
-
89
-
-
84896349895
-
The interdependence of membrane shape and cellular signal processing
-
Schmick M, Bastiaens PI. 2014. The interdependence of membrane shape and cellular signal processing. Cell 156:1132-38
-
(2014)
Cell
, vol.156
, pp. 1132-1138
-
-
Schmick, M.1
Bastiaens, P.I.2
-
90
-
-
84864131658
-
Substrate rigidity regulates human T cell activation and proliferation
-
O'Connor RS, Hao X, Shen K, Bashour K, Akimova T, et al. 2012. Substrate rigidity regulates human T cell activation and proliferation. J. Immunol. 189:1330-39
-
(2012)
J. Immunol.
, vol.189
, pp. 1330-1339
-
-
O'connor, R.S.1
Hao, X.2
Shen, K.3
Bashour, K.4
Akimova, T.5
-
91
-
-
84862628815
-
Photocrosslinkable pMHC monomers stain T cells specifically and cause ligand-bound TCRs to be 'preferentially' transported to the cSMAC
-
Xie J, Huppa JB, Newell EW, Huang J, Ebert PJ, et al. 2012. Photocrosslinkable pMHC monomers stain T cells specifically and cause ligand-bound TCRs to be 'preferentially' transported to the cSMAC. Nat. Immunol. 13:674-80
-
(2012)
Nat. Immunol.
, vol.13
, pp. 674-680
-
-
Xie, J.1
Huppa, J.B.2
Newell, E.W.3
Huang, J.4
Ebert, P.J.5
-
93
-
-
84892719664
-
Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling
-
Tan YX, Manz BN, Freedman TS, Zhang C, Shokat KM, Weiss A. 2014. Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling. Nat. Immunol. 15:186-94
-
(2014)
Nat. Immunol.
, vol.15
, pp. 186-194
-
-
Tan, Y.X.1
Manz, B.N.2
Freedman, T.S.3
Zhang, C.4
Shokat, K.M.5
Weiss, A.6
-
94
-
-
84923264984
-
Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor
-
Casas J, Brzostek J, Zarnitsyna VI, Hong JS, Wei Q, et al. 2014. Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor. Nat. Commun. 5:5624
-
(2014)
Nat. Commun.
, vol.5
, pp. 5624
-
-
Casas, J.1
Brzostek, J.2
Zarnitsyna, V.I.3
Hong, J.S.4
Wei, Q.5
-
95
-
-
84884220136
-
Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC
-
Hoerter JA, Brzostek J, Artyomov MN, Abel SM, Casas J, et al. 2013. Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC. J. Exp.Med. 210:1807-21
-
(2013)
J. Exp.Med.
, vol.210
, pp. 1807-1821
-
-
Hoerter, J.A.1
Brzostek, J.2
Artyomov, M.N.3
Abel, S.M.4
Casas, J.5
-
96
-
-
15044358353
-
Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity
-
Krogsgaard M, Li QJ, Sumen C, Huppa JB, Huse M, Davis MM. 2005. Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity. Nature 434:238-43
-
(2005)
Nature
, vol.434
, pp. 238-243
-
-
Krogsgaard, M.1
Li, Q.J.2
Sumen, C.3
Huppa, J.B.4
Huse, M.5
Davis, M.M.6
-
97
-
-
0041695164
-
Continuous T cell receptor signaling required for synapse maintenance and full effector potential
-
Huppa JB, Gleimer M, Sumen C, Davis MM. 2003. Continuous T cell receptor signaling required for synapse maintenance and full effector potential. Nat. Immunol. 4:749-55
-
(2003)
Nat. Immunol.
, vol.4
, pp. 749-755
-
-
Huppa, J.B.1
Gleimer, M.2
Sumen, C.3
Davis, M.M.4
-
98
-
-
84888141725
-
Visualizing how T cells collect activation signals in vivo
-
Moreau HD, Bousso P. 2014. Visualizing how T cells collect activation signals in vivo. Curr. Opin. Immunol. 26:56-62
-
(2014)
Curr. Opin. Immunol.
, vol.26
, pp. 56-62
-
-
Moreau, H.D.1
Bousso, P.2
-
99
-
-
0026659406
-
CD43 interferes with T-lymphocyte adhesion
-
Ardman B, Sikorski MA, Staunton DE. 1992. CD43 interferes with T-lymphocyte adhesion. PNAS 89:5001-5
-
(1992)
PNAS
, vol.89
, pp. 5001-5005
-
-
Ardman, B.1
Sikorski, M.A.2
Staunton, D.E.3
-
100
-
-
0023027034
-
Disoriented pathfinding by pioneer neurone growth cones deprived of filopodia by cytochalasin treatment
-
Bentley D, Toroian-Raymond A. 1986. Disoriented pathfinding by pioneer neurone growth cones deprived of filopodia by cytochalasin treatment. Nature 323:712-15
-
(1986)
Nature
, vol.323
, pp. 712-715
-
-
Bentley, D.1
Toroian-Raymond, A.2
-
102
-
-
0034624809
-
Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes
-
Leupin O, Zaru R, Laroche T, Muller S, Valitutti S. 2000. Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes. Curr. Biol. 10:277-80
-
(2000)
Curr. Biol.
, vol.10
, pp. 277-280
-
-
Leupin, O.1
Zaru, R.2
Laroche, T.3
Muller, S.4
Valitutti, S.5
-
103
-
-
0030922973
-
Leukosialin (CD43) behavior during adhesion of human monocytic THP-1 cells to red blood cells
-
Soler M, Merant C, Servant C, Fraterno M, Allasia C, et al. 1997. Leukosialin (CD43) behavior during adhesion of human monocytic THP-1 cells to red blood cells. J. Leukocyte Biol. 61:609-18
-
(1997)
J. Leukocyte Biol.
, vol.61
, pp. 609-618
-
-
Soler, M.1
Merant, C.2
Servant, C.3
Fraterno, M.4
Allasia, C.5
-
104
-
-
84860333171
-
Antigen recognition is facilitated by invadosome-like protrusions formed by memory/effector T cells
-
Sage PT, Varghese LM, Martinelli R, Sciuto TE, Kamei M, et al. 2012. Antigen recognition is facilitated by invadosome-like protrusions formed by memory/effector T cells. J. Immunol. 188:3686-99
-
(2012)
J. Immunol.
, vol.188
, pp. 3686-3699
-
-
Sage, P.T.1
Varghese, L.M.2
Martinelli, R.3
Sciuto, T.E.4
Kamei, M.5
-
105
-
-
54949103906
-
Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C? Translocation
-
Yokosuka T, Kobayashi W, Sakata-Sogawa K, Takamatsu M, Hashimoto-Tane A, et al. 2008. Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C? translocation. Immunity 29:589-601
-
(2008)
Immunity
, vol.29
, pp. 589-601
-
-
Yokosuka, T.1
Kobayashi, W.2
Sakata-Sogawa, K.3
Takamatsu, M.4
Hashimoto-Tane, A.5
-
106
-
-
64049108784
-
The cellular context of T cell signaling
-
Dustin ML. 2009. The cellular context of T cell signaling. Immunity 30:482-92
-
(2009)
Immunity
, vol.30
, pp. 482-492
-
-
Dustin, M.L.1
-
107
-
-
77951688912
-
Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster
-
Vardhana S, Choudhuri K, Varma R, Dustin ML. 2010. Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster. Immunity 32:531-40
-
(2010)
Immunity
, vol.32
, pp. 531-540
-
-
Vardhana, S.1
Choudhuri, K.2
Varma, R.3
Dustin, M.L.4
-
108
-
-
84895891752
-
Polarized release of T-cell-receptorenriched microvesicles at the immunological synapse
-
Choudhuri K, Llodra J, Roth EW, Tsai J, Gordo S, et al. 2014. Polarized release of T-cell-receptorenriched microvesicles at the immunological synapse. Nature 507:118-23
-
(2014)
Nature
, vol.507
, pp. 118-123
-
-
Choudhuri, K.1
Llodra, J.2
Roth, E.W.3
Tsai, J.4
Gordo, S.5
-
109
-
-
20844439947
-
Multifocal structure of the T cell-dendritic cell synapse
-
Brossard C, Feuillet V, Schmitt A, Randriamampita C, Romao M, et al. 2005. Multifocal structure of the T cell-dendritic cell synapse. Eur. J. Immunol. 35:1741-53
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 1741-1753
-
-
Brossard, C.1
Feuillet, V.2
Schmitt, A.3
Randriamampita, C.4
Romao, M.5
-
110
-
-
80054721880
-
CD4+ T-cell synapses involvemultiple distinct stages
-
Ueda H, MorphewMK, McIntosh JR,Davis MM. 2011. CD4+ T-cell synapses involvemultiple distinct stages. PNAS 108:17099-104
-
(2011)
PNAS
, vol.108
, pp. 17099-17104
-
-
Ueda, H.1
Morphew, M.K.2
McIntosh, J.R.3
Davis, M.M.4
-
111
-
-
84885347155
-
The actin-driven spatiotemporal organization of T-cell signaling at the system scale
-
Roybal KT, Sinai P, Verkade P, Murphy RF, Wulfing C. 2013. The actin-driven spatiotemporal organization of T-cell signaling at the system scale. Immunol. Rev. 256:133-47
-
(2013)
Immunol. Rev.
, vol.256
, pp. 133-147
-
-
Roybal, K.T.1
Sinai, P.2
Verkade, P.3
Murphy, R.F.4
Wulfing, C.5
-
112
-
-
0018420964
-
Themechanism of T-cell mediated cytotoxicity. VI.T-cell projections and their role in target cell killing
-
SandersonCJ, Glauert AM. 1979. Themechanism of T-cell mediated cytotoxicity. VI.T-cell projections and their role in target cell killing. Immunology 36:119-29
-
(1979)
Immunology
, vol.36
, pp. 119-129
-
-
Sanderson, C.J.1
Glauert, A.M.2
-
113
-
-
84876775237
-
Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation
-
Pratama A, Ramiscal RR, Silva DG, Das SK, Athanasopoulos V, et al. 2013. Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation. Immunity 38:669-80
-
(2013)
Immunity
, vol.38
, pp. 669-680
-
-
Pratama, A.1
Ramiscal, R.R.2
Silva, D.G.3
Das, S.K.4
Athanasopoulos, V.5
-
114
-
-
84880830434
-
The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells
-
Liang Y, Cucchetti M, Roncagalli R, Yokosuka T, Malzac A, et al. 2013. The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells. Nat. Immunol. 14:858-66
-
(2013)
Nat. Immunol.
, vol.14
, pp. 858-866
-
-
Liang, Y.1
Cucchetti, M.2
Roncagalli, R.3
Yokosuka, T.4
Malzac, A.5
-
115
-
-
84890561320
-
Themis sets the signal threshold for positive and negative selection in T-cell development
-
Fu G, Casas J, Rigaud S, Rybakin V, Lambolez F, et al. 2013. Themis sets the signal threshold for positive and negative selection in T-cell development. Nature 504:441-45
-
(2013)
Nature
, vol.504
, pp. 441-445
-
-
Fu, G.1
Casas, J.2
Rigaud, S.3
Rybakin, V.4
Lambolez, F.5
-
116
-
-
84897046940
-
Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub
-
Roncagalli R, Hauri S, Fiore F, Liang Y, Chen Z, et al. 2014. Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub. Nat. Immunol. 15:384-92
-
(2014)
Nat. Immunol.
, vol.15
, pp. 384-392
-
-
Roncagalli, R.1
Hauri, S.2
Fiore, F.3
Liang, Y.4
Chen, Z.5
-
118
-
-
33748366578
-
Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1
-
Houtman JC, Yamaguchi H, Barda-Saad M, Braiman A, Bowden B, et al. 2006. Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1. Nat. Struct. Mol. Biol. 13:798-805
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 798-805
-
-
Houtman, J.C.1
Yamaguchi, H.2
Barda-Saad, M.3
Braiman, A.4
Bowden, B.5
-
119
-
-
81955164142
-
Functional nanoscale organization of signaling molecules downstream of the T cell antigen receptor
-
Sherman E, Barr V, Manley S, Patterson G, Balagopalan L, et al. 2011. Functional nanoscale organization of signaling molecules downstream of the T cell antigen receptor. Immunity 35:705-20
-
(2011)
Immunity
, vol.35
, pp. 705-720
-
-
Sherman, E.1
Barr, V.2
Manley, S.3
Patterson, G.4
Balagopalan, L.5
-
120
-
-
84888093616
-
The ability of Sos1 to oligomerize the adaptor protein LAT is separable from its guanine nucleotide exchange activity in vivo
-
Kortum RL, Balagopalan L, Alexander CP, Garcia J, Pinski JM, et al. 2013. The ability of Sos1 to oligomerize the adaptor protein LAT is separable from its guanine nucleotide exchange activity in vivo. Sci. Signal. 6:ra99
-
(2013)
Sci. Signal.
, vol.6
, pp. ra99
-
-
Kortum, R.L.1
Balagopalan, L.2
Alexander, C.P.3
Garcia, J.4
Pinski, J.M.5
-
121
-
-
80052211582
-
Rapid phospho-turnover by receptor tyrosine kinases impacts downstream signaling and drug binding
-
Kleiman LB, Maiwald T, Conzelmann H, Lauffenburger DA, Sorger PK. 2011. Rapid phospho-turnover by receptor tyrosine kinases impacts downstream signaling and drug binding. Mol. Cell 43:723-37
-
(2011)
Mol. Cell
, vol.43
, pp. 723-737
-
-
Kleiman, L.B.1
Maiwald, T.2
Conzelmann, H.3
Lauffenburger, D.A.4
Sorger, P.K.5
-
123
-
-
84923207688
-
Scientific method: Defend the integrity of physics
-
Ellis G, Silk J. 2014. Scientific method: Defend the integrity of physics. Nature 516:321-23
-
(2014)
Nature
, vol.516
, pp. 321-323
-
-
Ellis, G.1
Silk, J.2
-
124
-
-
84890506631
-
Life at low Reynolds number
-
Purcell EM. 1977. Life at low Reynolds number. Am. J. Phys. 45:3-11
-
(1977)
Am. J. Phys.
, vol.45
, pp. 3-11
-
-
Purcell, E.M.1
-
125
-
-
34247127891
-
Quantitative network signal combinations downstream of TCR activation can predict IL-2 production response
-
Kemp ML, Wille L, Lewis CL, Nicholson LB, Lauffenburger DA. 2007. Quantitative network signal combinations downstream of TCR activation can predict IL-2 production response. J. Immunol. 178:4984-92
-
(2007)
J. Immunol.
, vol.178
, pp. 4984-4992
-
-
Kemp, M.L.1
Wille, L.2
Lewis, C.L.3
Nicholson, L.B.4
Lauffenburger, D.A.5
-
126
-
-
84904443484
-
Tcell receptor-dependent signal intensity dominantly controls CD4+ T cell polarization in vivo
-
van Panhuys N, Klauschen F,Germain RN. 2014.Tcell receptor-dependent signal intensity dominantly controls CD4+ T cell polarization in vivo. Immunity 41:63-74
-
(2014)
Immunity
, vol.41
, pp. 63-74
-
-
Van Panhuys, N.1
Klauschen, F.2
Germain, R.N.3
-
127
-
-
0016827251
-
Migration and chemotaxis of anucleate cytoplasmic leukocyte fragments
-
Keller HU, Bessis M. 1975. Migration and chemotaxis of anucleate cytoplasmic leukocyte fragments. Nature 258:723-24
-
(1975)
Nature
, vol.258
, pp. 723-724
-
-
Keller, H.U.1
Bessis, M.2
-
128
-
-
0020449117
-
The cytokineplast: Purified, stable, and functionalmotile machinery from human blood polymorphonuclear leukocytes
-
Malawista SE,De Boisfleury Chevance A. 1982. The cytokineplast: purified, stable, and functionalmotile machinery from human blood polymorphonuclear leukocytes. J. Cell Biol. 95:960-73
-
(1982)
J. Cell Biol.
, vol.95
, pp. 960-973
-
-
Malawista, S.E.1
De Boisfleury Chevance, A.2
-
129
-
-
84855479406
-
Actin disassembly clock determines shape and speed of lamellipodial fragments
-
Ofer N, Mogilner A, KerenK. 2011. Actin disassembly clock determines shape and speed of lamellipodial fragments. PNAS 108:20394-99
-
(2011)
PNAS
, vol.108
, pp. 20394-20399
-
-
Ofer, N.1
Mogilner, A.2
Keren, K.3
-
130
-
-
44349189707
-
Rapid signal transduction in living cells is a unique feature of mechanotransduction
-
Na S, Collin O, Chowdhury F, Tay B, Ouyang M, et al. 2008. Rapid signal transduction in living cells is a unique feature of mechanotransduction. PNAS 105:6626-31
-
(2008)
PNAS
, vol.105
, pp. 6626-6631
-
-
Na, S.1
Collin, O.2
Chowdhury, F.3
Tay, B.4
Ouyang, M.5
-
131
-
-
45249124996
-
A novel ZAP-70 dependent FRET based biosensor reveals kinase activity at both the immunological synapse and the antisynapse
-
Randriamampita C, Mouchacca P, Malissen B, Marguet D, Trautmann A, Lellouch AC. 2008. A novel ZAP-70 dependent FRET based biosensor reveals kinase activity at both the immunological synapse and the antisynapse. PLOS ONE 3:e1521
-
(2008)
PLOS ONE
, vol.3
, pp. e1521
-
-
Randriamampita, C.1
Mouchacca, P.2
Malissen, B.3
Marguet, D.4
Trautmann, A.5
Lellouch, A.C.6
-
132
-
-
0032864252
-
Spatial gradients of cellular phospho-proteins
-
Brown GC, Kholodenko BN. 1999. Spatial gradients of cellular phospho-proteins. FEBS Lett. 457:452-54
-
(1999)
FEBS Lett.
, vol.457
, pp. 452-454
-
-
Brown, G.C.1
Kholodenko, B.N.2
-
133
-
-
84866374306
-
A steep phosphoinositide bis-phosphate gradient forms during fungal filamentous growth
-
Vernay A, Schaub S, Guillas I, BassilanaM, Arkowitz RA. 2012. A steep phosphoinositide bis-phosphate gradient forms during fungal filamentous growth. J. Cell Biol. 198:711-30
-
(2012)
J. Cell Biol.
, vol.198
, pp. 711-730
-
-
Vernay, A.1
Schaub, S.2
Guillas, I.3
Bassilana, M.4
Arkowitz, R.A.5
-
134
-
-
78049285759
-
Real-time single-cell response to stiffness
-
Mitrossilis D, Fouchard J, Pereira D, Postic F, Richert A, et al. 2010. Real-time single-cell response to stiffness. PNAS 107:16518-23
-
(2010)
PNAS
, vol.107
, pp. 16518-16523
-
-
Mitrossilis, D.1
Fouchard, J.2
Pereira, D.3
Postic, F.4
Richert, A.5
-
135
-
-
0034698511
-
Subsecond induction of α4 integrin clustering by immobilized chemokines stimulates leukocyte tethering and rolling on endothelial vascular cell adhesion molecule 1 under flow conditions
-
Grabovsky V, Feigelson S, Chen C, Bleijs DA, Peled A, et al. 2000. Subsecond induction of α4 integrin clustering by immobilized chemokines stimulates leukocyte tethering and rolling on endothelial vascular cell adhesion molecule 1 under flow conditions. J. Exp. Med. 192:495-506
-
(2000)
J. Exp. Med.
, vol.192
, pp. 495-506
-
-
Grabovsky, V.1
Feigelson, S.2
Chen, C.3
Bleijs, D.A.4
Peled, A.5
-
136
-
-
33744809296
-
A global analysis of cross-talk in a mammalian cellular signalling network
-
Natarajan M, Lin KM, Hsueh RC, Sternweis PC, Ranganathan R. 2006. A global analysis of cross-talk in a mammalian cellular signalling network. Nat. Cell Biol. 8:571-80
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 571-580
-
-
Natarajan, M.1
Lin, K.M.2
Hsueh, R.C.3
Sternweis, P.C.4
Ranganathan, R.5
-
137
-
-
84874765320
-
Encoding and decoding cellular information through signaling dynamics
-
Purvis JE, Lahav G. 2013. Encoding and decoding cellular information through signaling dynamics. Cell 152:945-56
-
(2013)
Cell
, vol.152
, pp. 945-956
-
-
Purvis, J.E.1
Lahav, G.2
-
138
-
-
0037290768
-
Epitope dominance, competition andTcell affinitymaturation
-
Kedl RM,Kappler JW,Marrack P. 2003. Epitope dominance, competition andTcell affinitymaturation. Curr. Opin. Immunol. 15:120-27
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 120-127
-
-
Kedl, R.M.1
Kappler, J.W.2
Marrack, P.3
-
139
-
-
77953639786
-
Cutting edge: Lack of high affinity competition for peptide in polyclonal CD4+ responses unmasks IL-4 production
-
Milner JD, Fazilleau N, McHeyzer-Williams M, Paul W. 2010. Cutting edge: lack of high affinity competition for peptide in polyclonal CD4+ responses unmasks IL-4 production. J. Immunol. 184:6569-73
-
(2010)
J. Immunol.
, vol.184
, pp. 6569-6573
-
-
Milner, J.D.1
Fazilleau, N.2
McHeyzer-Williams, M.3
Paul, W.4
-
140
-
-
66449090934
-
Reprogramming cell fates: Reconciling rarity with robustness
-
Huang S. 2009. Reprogramming cell fates: reconciling rarity with robustness. BioEssays 31:546-60
-
(2009)
BioEssays
, vol.31
, pp. 546-560
-
-
Huang, S.1
-
141
-
-
78049424847
-
Diversity and plasticity of Th cell types predicted from regulatory network modelling
-
Naldi A, Carneiro J, Chaouiya C, Thieffry D. 2010. Diversity and plasticity of Th cell types predicted from regulatory network modelling. PLOS Comput. Biol. 6:e1000912
-
(2010)
PLOS Comput. Biol.
, vol.6
, pp. e1000912
-
-
Naldi, A.1
Carneiro, J.2
Chaouiya, C.3
Thieffry, D.4
-
142
-
-
0033555859
-
Emergent properties of networks of biological signaling pathways
-
Bhalla US, Iyengar R. 1999. Emergent properties of networks of biological signaling pathways. Science 283:381-87
-
(1999)
Science
, vol.283
, pp. 381-387
-
-
Bhalla, U.S.1
Iyengar, R.2
|