A novel ZAP-70 dependent FRET based biosensor reveals kinase activity at both the immunological synapse and the antisynapse

PLoS ONE

Volumn 3, Issue 1, 2008, Pages

  Randriamampita, Clotilde ^a,b   Mouchacca, Pierre ^b,c,d   Malissen, Bernard ^b,c,d   Marguet, Didier ^b,c   Trautmann, Alain ^a,b   Lellouch, Annemarie Coffman ^b,c,d  

^a INSTITUT COCHIN   (France)

^b INSERM   (France)

^c CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^d CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; PROTEIN KINASE ZAP 70; PROTEINASE; SECRETORY LEUKOCYTE PROTEINASE 76; SOS PROTEIN; T LYMPHOCYTE RECEPTOR; PROTEIN KINASE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME KINETICS; ENZYME LOCALIZATION; ENZYMIC BIOSENSOR; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; IMMUNE RESPONSE; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; CELL FRACTIONATION; GENETIC PROCEDURES; IMMUNOLOGY; LEUKEMIA CELL LINE; LYMPHOCYTE ACTIVATION; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SYNAPSE; T LYMPHOCYTE;

BIOSENSING TECHNIQUES; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; JURKAT CELLS; LYMPHOCYTE ACTIVATION; PHOSPHORYLATION; PROTEIN KINASES; SUBCELLULAR FRACTIONS; SYNAPSES; T-LYMPHOCYTES; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 45249124996     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001521     Document Type: Article

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