Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity

Nature

Volumn 434, Issue 7030, 2005, Pages 238-243

  Krogsgaard, Michelle ^a   Li, Qi Jing ^a   Sumen, Cenk ^a,b   Huppa, Johannes B ^a   Huse, Morgan ^a   Davis, Mark M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; BIOCOMPATIBILITY; CELLS; HISTOLOGY; LIPIDS; PROTEINS;

CELL ACTIVATION; HETERODIMERS; LIGANDS; LYMPHOCYTES; MAJOR HISTOCOMPATIBILITY COMPLEX (MHC);

DIMERS;

DIMER; HETERODIMER; LIGAND; PEPTIDE; UNCLASSIFIED DRUG; HLA ANTIGEN; INTERLEUKIN 2; LYMPHOCYTE ANTIGEN RECEPTOR;

MEDICINE;

AGONIST; ARTICLE; BINDING SITE; CELL ACTIVATION; HELPER CELL; LIPID BILAYER; MAJOR HISTOCOMPATIBILITY COMPLEX; MUTATION; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; AMINO ACID SEQUENCE; ANIMAL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; BIOSYNTHESIS; CALCIUM SIGNALING; CD4+ T LYMPHOCYTE; CHEMISTRY; CHO CELL; DIMERIZATION; HAMSTER; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; MOLECULAR GENETICS; MOUSE; SENSITIVITY AND SPECIFICITY;

AMINO ACID SEQUENCE; ANIMALS; ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; CALCIUM SIGNALING; CD4-POSITIVE T-LYMPHOCYTES; CHO CELLS; CRICETINAE; DIMERIZATION; HLA ANTIGENS; INTERLEUKIN-2; LIPID BILAYERS; LYMPHOCYTE ACTIVATION; MICE; MOLECULAR SEQUENCE DATA; PEPTIDES; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SENSITIVITY AND SPECIFICITY;

EID: 15044358353     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03391     Document Type: Article

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