-
1
-
-
81955164077
-
T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex
-
doi: 10.1016/j.immuni.2011.09.013
-
Adams JJ, Narayanan S, Liu B, Birnbaum ME, Kruse AC, Bowerman NA, et al. 2011. T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex. Immunity 35:681-93. doi: 10.1016/j.immuni.2011.09.013.
-
(2011)
Immunity
, vol.35
, pp. 681-693
-
-
Adams, J.J.1
Narayanan, S.2
Liu, B.3
Birnbaum, M.E.4
Kruse, A.C.5
Bowerman, N.A.6
-
2
-
-
27844541328
-
Modeling T Cell antigen discrimination based on feedback control of digital ERK responses
-
doi: 10.1371/journal.pbio.0030356
-
Altan-Bonnet G, Germain RN. 2005. Modeling T Cell antigen discrimination based on feedback control of digital ERK responses. PLoS Biol 3:e356. doi: 10.1371/journal.pbio.0030356.
-
(2005)
PLoS Biol
, vol.3
-
-
Altan-Bonnet, G.1
Germain, R.N.2
-
3
-
-
84864775640
-
Determination of interaction kinetics between the T cell receptor and peptide-loaded MHC class II via single-molecule diffusion measurements
-
doi: 10.1016/j.bpj.2012.06.019
-
Axmann M, Huppa JB, Davis MM, Schütz GJ. 2012. Determination of interaction kinetics between the T cell receptor and peptide-loaded MHC class II via single-molecule diffusion measurements. Biophys J 103:L17-9. doi: 10.1016/j.bpj.2012.06.019.
-
(2012)
Biophys J
, vol.103
-
-
Axmann, M.1
Huppa, J.B.2
Davis, M.M.3
Schütz, G.J.4
-
4
-
-
0037144842
-
T cell receptor ligation induces the formation of dynamically regulated signaling assemblies
-
doi: 10.1083/jcb.200203043
-
Bunnell SC, Hong DI, Kardon JR, Yamazaki T, McGlade CJ, Barr VA, et al. 2002. T cell receptor ligation induces the formation of dynamically regulated signaling assemblies. J Cell Biol 158:1263-75. doi: 10.1083/jcb.200203043.
-
(2002)
J Cell Biol
, vol.158
, pp. 1263-1275
-
-
Bunnell, S.C.1
Hong, D.I.2
Kardon, J.R.3
Yamazaki, T.4
McGlade, C.J.5
Barr, V.A.6
-
5
-
-
0036789459
-
Differential segregation in a cell-cell contact interface: The dynamics of the immunological synapse
-
doi: 10.1016/S0006-3495(02)73944-1
-
Burroughs NJ, Wulfing C. 2002. Differential segregation in a cell-cell contact interface: the dynamics of the immunological synapse. Biophys J 83:1784-96. doi: 10.1016/S0006-3495(02)73944-1.
-
(2002)
Biophys J
, vol.83
, pp. 1784-1796
-
-
Burroughs, N.J.1
Wulfing, C.2
-
6
-
-
27544441784
-
Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
-
doi: 10.1084/jem.20051182
-
Campi G, Varma R, Dustin ML. 2005. Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. J Exp Med 202:1031-6. doi: 10.1084/jem.20051182.
-
(2005)
J Exp Med
, vol.202
, pp. 1031-1036
-
-
Campi, G.1
Varma, R.2
Dustin, M.L.3
-
7
-
-
2342520684
-
Feedback control of T-cell receptor activation
-
doi: 10.1098/rspb.2003.2587
-
Chan C, Stark J, George AJ. 2004. Feedback control of T-cell receptor activation. Proc Biol Sci 271:931-9. doi: 10.1098/rspb.2003.2587.
-
(2004)
Proc Biol Sci
, vol.271
, pp. 931-939
-
-
Chan, C.1
Stark, J.2
George, A.J.3
-
8
-
-
44349161113
-
A mechanism for Src kinase-dependent signaling by noncatalytic receptors
-
doi: 10.1021/bi8003044
-
Cooper JA, Qian H. 2008. A mechanism for Src kinase-dependent signaling by noncatalytic receptors. Biochemistry 47:5681-8. doi: 10.1021/bi8003044.
-
(2008)
Biochemistry
, vol.47
, pp. 5681-5688
-
-
Cooper, J.A.1
Qian, H.2
-
9
-
-
77955375356
-
Attenuated T cell responses to a high-potency ligand in vivo
-
doi: 10.1371/journal.pbio.1000481
-
Corse E, Gottschalk RA, Krogsgaard M, Allison JP. 2010. Attenuated T cell responses to a high-potency ligand in vivo. PLOS Biol 8:e1000481. doi: 10.1371/journal.pbio.1000481.
-
(2010)
PLOS Biol
, vol.8
-
-
Corse, E.1
Gottschalk, R.A.2
Krogsgaard, M.3
Allison, J.P.4
-
10
-
-
0029977418
-
Methods of digital video microscopy for colloidal studies
-
doi: 10.1006/jcis.1996.0217
-
Crocker JC, Grier DG. 1996. Methods of digital video microscopy for colloidal studies. J Colloid Interface Sci 179:298-310. doi: 10.1006/jcis.1996.0217.
-
(1996)
J Colloid Interface Sci
, vol.179
, pp. 298-310
-
-
Crocker, J.C.1
Grier, D.G.2
-
11
-
-
58249092059
-
Digital signaling and hysteresis characterize ras activation in lymphoid cells
-
doi: 10.1016/j.cell.2008.11.051
-
Das J, Ho M, Zikherman J, Govern C, Yang M, Weiss A, et al. 2009. Digital signaling and hysteresis characterize ras activation in lymphoid cells. Cell 136:337-51. doi: 10.1016/j.cell.2008.11.051.
-
(2009)
Cell
, vol.136
, pp. 337-351
-
-
Das, J.1
Ho, M.2
Zikherman, J.3
Govern, C.4
Yang, M.5
Weiss, A.6
-
12
-
-
43149088046
-
T cell receptor microcluster transport through molecular mazes reveals mechanism of translocation
-
doi: 10.1529/biophysj.107.119099
-
DeMond AL, Mossman KD, Starr T, Dustin ML, Groves JT. 2008. T cell receptor microcluster transport through molecular mazes reveals mechanism of translocation. Biophys J 94:3286-92. doi: 10.1529/biophysj.107.119099.
-
(2008)
Biophys J
, vol.94
, pp. 3286-3292
-
-
DeMond, A.L.1
Mossman, K.D.2
Starr, T.3
Dustin, M.L.4
Groves, J.T.5
-
13
-
-
78650186363
-
Lipidbook: A public repository for force-field parameters used in membrane simulations
-
doi: 10.1007/s00232-010-9296-8
-
Domanski J, Stansfeld P, Sansom MP, Beckstein O. 2010. Lipidbook: a public repository for force-field parameters used in membrane simulations. J Membr Biol 236:255-8. doi: 10.1007/s00232-010-9296-8.
-
(2010)
J Membr Biol
, vol.236
, pp. 255-258
-
-
Domanski, J.1
Stansfeld, P.2
Sansom, M.P.3
Beckstein, O.4
-
14
-
-
84861403073
-
Receptor signaling clusters in the immune synapse
-
doi: 10.1146/annurev-biophys-042910-155238
-
Dustin ML, Groves JT. 2012. Receptor signaling clusters in the immune synapse. Annu Rev Biophys 41:543-56. doi: 10.1146/annurev-biophys-042910-155238.
-
(2012)
Annu Rev Biophys
, vol.41
, pp. 543-556
-
-
Dustin, M.L.1
Groves, J.T.2
-
15
-
-
75649140873
-
Bayesian detection of intensity changes in single molecule and molecular dynamics trajectories
-
doi: 10.1021/jp906786b
-
Ensign DL, Pande VS. 2009. Bayesian detection of intensity changes in single molecule and molecular dynamics trajectories. J Phys Chem B 114:280-92. doi: 10.1021/jp906786b.
-
(2009)
J Phys Chem B
, vol.114
, pp. 280-292
-
-
Ensign, D.L.1
Pande, V.S.2
-
16
-
-
77952712883
-
Fast on-rates allow short dwell time ligands to activate T cells
-
doi: 10.1073/pnas.1000966107
-
Govern CC, Paczosa MK, Chakraborty AK, Huseby ES. 2010. Fast on-rates allow short dwell time ligands to activate T cells. Proc Natl Acad Sci USA 107:8724-9. doi: 10.1073/pnas.1000966107.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 8724-8729
-
-
Govern, C.C.1
Paczosa, M.K.2
Chakraborty, A.K.3
Huseby, E.S.4
-
17
-
-
0033538574
-
The immunological synapse: A molecular machine controlling T cell activation
-
doi: 10.1126/science.285.5425.221
-
Grakoui A, Bromley SK, Sumen C, Davis MM, Shaw AS, Allen PM, et al. 1999. The immunological synapse: a molecular machine controlling T cell activation. Science 285:221-7. doi: 10.1126/science.285.5425.221.
-
(1999)
Science
, vol.285
, pp. 221-227
-
-
Grakoui, A.1
Bromley, S.K.2
Sumen, C.3
Davis, M.M.4
Shaw, A.S.5
Allen, P.M.6
-
18
-
-
0033514435
-
Single-molecule fluorescence spectroscopy of enzyme conformational dynamics and cleavage mechanism
-
doi: 10.1073/pnas.96.3.893
-
Ha T, Ting AY, Liang J, Caldwell WB, Deniz AA, Chemla DS, et al. 1999. Single-molecule fluorescence spectroscopy of enzyme conformational dynamics and cleavage mechanism. Proc Natl Acad Sci USA 96:893-8. doi: 10.1073/pnas.96.3.893.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 893-898
-
-
Ha, T.1
Ting, A.Y.2
Liang, J.3
Caldwell, W.B.4
Deniz, A.A.5
Chemla, D.S.6
-
19
-
-
84862589122
-
Cutting edge: Evidence for a dynamically driven T cell signaling mechanism
-
doi: 10.4049/jimmunol.1200952
-
Hawse WF, Champion MM, Joyce MV, Hellman LM, Hossain M, Ryan V, et al. 2012. Cutting edge: evidence for a dynamically driven T cell signaling mechanism. J Immunol 188:5819-23. doi: 10.4049/jimmunol.1200952.
-
(2012)
J Immunol
, vol.188
, pp. 5819-5823
-
-
Hawse, W.F.1
Champion, M.M.2
Joyce, M.V.3
Hellman, L.M.4
Hossain, M.5
Ryan, V.6
-
20
-
-
77950809538
-
The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness
-
doi: 10.1038/nature08944
-
Huang J, Zarnitsyna VI, Liu B, Edwards LJ, Jiang N, Evavold BD, et al. 2010. The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness. Nature 464:932-6. doi: 10.1038/nature08944.
-
(2010)
Nature
, vol.464
, pp. 932-936
-
-
Huang, J.1
Zarnitsyna, V.I.2
Liu, B.3
Edwards, L.J.4
Jiang, N.5
Evavold, B.D.6
-
21
-
-
77249114784
-
TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity
-
doi: 10.1038/nature08746
-
Huppa JB, Axmann M, Mortelmaier MA, Lillemeier BF, Newell EW, Brameshuber M, et al. 2010. TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity. Nature 463:963-7. doi: 10.1038/nature08746.
-
(2010)
Nature
, vol.463
, pp. 963-967
-
-
Huppa, J.B.1
Axmann, M.2
Mortelmaier, M.A.3
Lillemeier, B.F.4
Newell, E.W.5
Brameshuber, M.6
-
22
-
-
34447647655
-
Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist
-
doi: 10.1016/j.immuni.2007.05.017
-
Huse M, Klein LO, Girvin AT, Faraj JM, Li Q-J, Kuhns MS, et al. 2007. Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist. Immunity 27:76-88. doi: 10.1016/j.immuni.2007.05.017.
-
(2007)
Immunity
, vol.27
, pp. 76-88
-
-
Huse, M.1
Klein, L.O.2
Girvin, A.T.3
Faraj, J.M.4
Li, Q.-J.5
Kuhns, M.S.6
-
23
-
-
0037167816
-
Direct observation of ligand recognition by T cells
-
doi: 10.1038/nature01076
-
Irvine DJ, Purbhoo MA, Krogsgaard M, Davis MM. 2002. Direct observation of ligand recognition by T cells. Nature 419:845-9. doi: 10.1038/nature01076.
-
(2002)
Nature
, vol.419
, pp. 845-849
-
-
Irvine, D.J.1
Purbhoo, M.A.2
Krogsgaard, M.3
Davis, M.M.4
-
24
-
-
0028209548
-
Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases
-
doi: 10.1126/science.7509083
-
Iwashima M, Irving BA, van Oers NS, Chan AC, Weiss A. 1994. Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science 263:1136-9. doi: 10.1126/science.7509083.
-
(1994)
Science
, vol.263
, pp. 1136-1139
-
-
Iwashima, M.1
Irving, B.A.2
van Oers, N.S.3
Chan, A.C.4
Weiss, A.5
-
25
-
-
38049136514
-
Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells
-
doi: 10.1073/pnas.0710258105
-
Kaizuka Y, Douglass AD, Varma R, Dustin ML, Vale RD. 2007. Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells. Proc Natl Acad Sci USA 104:20296-301. doi: 10.1073/pnas.0710258105.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20296-20301
-
-
Kaizuka, Y.1
Douglass, A.D.2
Varma, R.3
Dustin, M.L.4
Vale, R.D.5
-
26
-
-
0024444304
-
Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor
-
doi: 10.1038/341746a0
-
Kaye J, Hsu ML, Sauron ME, Jameson SC, Gascoigne NR, Hedrick SM. 1989. Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor. Nature 341:746-9. doi: 10.1038/341746a0.
-
(1989)
Nature
, vol.341
, pp. 746-749
-
-
Kaye, J.1
Hsu, M.L.2
Sauron, M.E.3
Jameson, S.C.4
Gascoigne, N.R.5
Hedrick, S.M.6
-
27
-
-
15044358353
-
Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity
-
doi: 10.1038/nature03391
-
Krogsgaard M, Li QJ, Sumen C, Huppa JB, Huse M, Davis MM. 2005. Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity. Nature 434:238-43. doi: 10.1038/nature03391.
-
(2005)
Nature
, vol.434
, pp. 238-243
-
-
Krogsgaard, M.1
Li, Q.J.2
Sumen, C.3
Huppa, J.B.4
Huse, M.5
Davis, M.M.6
-
28
-
-
80755166293
-
Supported membrane formation, characterization, functionalization, and patterning for application in biological science and technology
-
John Wiley & Sons, Inc, doi: 10.1002/9780470559277.ch100131
-
Lin W-C, Yu C-H, Triffo S, Groves JT. 2010. Supported membrane formation, characterization, functionalization, and patterning for application in biological science and technology. In Current protocols in chemical biology 2. John Wiley & Sons, Inc. pp. 235-69. doi: 10.1002/9780470559277.ch100131.
-
(2010)
In Current protocols in chemical biology
, vol.2
, pp. 235-269
-
-
Lin, W.-C.1
Yu, C.-H.2
Triffo, S.3
Groves, J.T.4
-
29
-
-
34547880034
-
Single-molecule FRET reveals sugar-induced conformational dynamics in LacY
-
doi: 10.1073/pnas.0700969104
-
Majumdar DS, Smirnova I, Kasho V, Nir E, Kong X, Weiss S, et al. 2007. Single-molecule FRET reveals sugar-induced conformational dynamics in LacY. Proc Natl Acad Sci USA 104:12640-5. doi: 10.1073/pnas.0700969104.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12640-12645
-
-
Majumdar, D.S.1
Smirnova, I.2
Kasho, V.3
Nir, E.4
Kong, X.5
Weiss, S.6
-
30
-
-
79959328071
-
T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters
-
doi: 10.1073/pnas.1018771108
-
Manz BN, Jackson BL, Petit RS, Dustin ML, Groves J. 2011. T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters. Proc Natl Acad Sci USA 108:9089-94. doi: 10.1073/pnas.1018771108.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 9089-9094
-
-
Manz, B.N.1
Jackson, B.L.2
Petit, R.S.3
Dustin, M.L.4
Groves, J.5
-
31
-
-
0028589333
-
Kinetics of T-cell receptor binding to peptide/I-Ek complexes: Correlation of the dissociation rate with T-cell responsiveness
-
doi: 10.1073/pnas.91.26.12862
-
Matsui K, Boniface JJ, Steffner P, Reay PA, Davis MM. 1994. Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness. Proc Natl Acad Sci USA 91:12862-6. doi: 10.1073/pnas.91.26.12862.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12862-12866
-
-
Matsui, K.1
Boniface, J.J.2
Steffner, P.3
Reay, P.A.4
Davis, M.M.5
-
32
-
-
0029063148
-
Kinetic proofreading in T-cell receptor signal transduction
-
doi: 10.1073/pnas.92.11.5042
-
McKeithan TW. 1995. Kinetic proofreading in T-cell receptor signal transduction. Proc Natl Acad Sci USA 92:5042-6. doi: 10.1073/pnas.92.11.5042.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5042-5046
-
-
McKeithan, T.W.1
-
33
-
-
79956221437
-
Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k)
-
doi: 10.4049/jimmunol.1100197
-
Newell EW, Ely LK, Kruse AC, Reay PA, Rodriguez SN, Lin AE, et al. 2011. Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k). J Immunol 186:5823-32. doi: 10.4049/jimmunol.1100197.
-
(2011)
J Immunol
, vol.186
, pp. 5823-5832
-
-
Newell, E.W.1
Ely, L.K.2
Kruse, A.C.3
Reay, P.A.4
Rodriguez, S.N.5
Lin, A.E.6
-
34
-
-
42449096835
-
Kinetic control of Histidine-tagged protein surface density on supported lipid bilayers
-
doi: 10.1021/la703788h
-
Nye JA, Groves JT. 2008. Kinetic control of Histidine-tagged protein surface density on supported lipid bilayers. Langmuir 24:4145-9. doi: 10.1021/la703788h.
-
(2008)
Langmuir
, vol.24
, pp. 4145-4149
-
-
Nye, J.A.1
Groves, J.T.2
-
35
-
-
61349149901
-
Affinity threshold for thymic selection through a T-cell receptor-co-receptor zipper
-
doi: 10.1038/nri2469
-
Palmer E, Naeher D. 2009. Affinity threshold for thymic selection through a T-cell receptor-co-receptor zipper. Nat Rev Immunol 9:207-13. doi: 10.1038/nri2469.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 207-213
-
-
Palmer, E.1
Naeher, D.2
-
36
-
-
0035811008
-
Synaptic pattern formation during cellular recognition
-
doi: 10.1073/pnas.111536798
-
Qi SY, Groves JT, Chakraborty AK. 2001. Synaptic pattern formation during cellular recognition. Proc Natl Acad Sci USA 98:6548-53. doi: 10.1073/pnas.111536798.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6548-6553
-
-
Qi, S.Y.1
Groves, J.T.2
Chakraborty, A.K.3
-
37
-
-
0029926145
-
Kinetic discrimination in T-cell activation
-
doi: 10.1073/pnas.93.4.1401
-
Rabinowitz JD, Beeson C, Lyons DS, Davis MM, McConnell HM. 1996. Kinetic discrimination in T-cell activation. Proc Natl Acad Sci USA 93:1401-5. doi: 10.1073/pnas.93.4.1401.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1401-1405
-
-
Rabinowitz, J.D.1
Beeson, C.2
Lyons, D.S.3
Davis, M.M.4
McConnell, H.M.5
-
38
-
-
84861128851
-
Epitope flexibility and dynamic footprint revealed by molecular dynamics of a pMHC-TCR complex
-
doi: 10.1371/journal.pcbi.1002404
-
Reboul CF, Meyer GR, Porebski BT, Borg NA, Buckle AM. 2012. Epitope flexibility and dynamic footprint revealed by molecular dynamics of a pMHC-TCR complex. PLOS Comput Biol 8:e1002404. doi: 10.1371/journal.pcbi.1002404.
-
(2012)
PLOS Comput Biol
, vol.8
-
-
Reboul, C.F.1
Meyer, G.R.2
Porebski, B.T.3
Borg, N.A.4
Buckle, A.M.5
-
39
-
-
84871424424
-
Organization of the resting TCR in nanoscale oligomers
-
doi: 10.1111/imr.12019
-
Schamel WW, Alarcon B. 2013. Organization of the resting TCR in nanoscale oligomers. Immunol Rev 251:13-20. doi: 10.1111/imr.12019.
-
(2013)
Immunol Rev
, vol.251
, pp. 13-20
-
-
Schamel, W.W.1
Alarcon, B.2
-
40
-
-
0030927323
-
Making the T cell receptor go the distance: A topological view of T cell activation
-
doi: 10.1016/S1074-7613(00)80279-4
-
Shaw AS, Dustin ML. 1997. Making the T cell receptor go the distance: a topological view of T cell activation. Immunity 6:361-9. doi: 10.1016/S1074-7613(00)80279-4.
-
(1997)
Immunity
, vol.6
, pp. 361-369
-
-
Shaw, A.S.1
Dustin, M.L.2
-
41
-
-
79955435814
-
Patterned two-photon photoactivation illuminates spatial reorganization in live cells
-
doi: 10.1021/jp108295s
-
Smith AW, Smoligovets AA, Groves JT. 2011. Patterned two-photon photoactivation illuminates spatial reorganization in live cells. J Phys Chem A 115:3867-75. doi: 10.1021/jp108295s.
-
(2011)
J Phys Chem A
, vol.115
, pp. 3867-3875
-
-
Smith, A.W.1
Smoligovets, A.A.2
Groves, J.T.3
-
42
-
-
84863262312
-
Characterization of dynamic actin associations with T-cell receptor microclusters in primary T cells
-
doi: 10.1242/jcs.092825
-
Smoligovets AA, Smith AW, Wu H-J, Petit RS, Groves JT. 2012. Characterization of dynamic actin associations with T-cell receptor microclusters in primary T cells. J Cell Sci 125:735-42. doi: 10.1242/jcs.092825.
-
(2012)
J Cell Sci
, vol.125
, pp. 735-742
-
-
Smoligovets, A.A.1
Smith, A.W.2
Wu, H.-J.3
Petit, R.S.4
Groves, J.T.5
-
43
-
-
0037338890
-
TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways
-
doi: 10.1038/ni895
-
Stefanová I, Hemmer B, Vergelli M, Martin R, Biddison WE, Germain RN. 2003. TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways. Nat Immunol 4:248-54. doi: 10.1038/ni895.
-
(2003)
Nat Immunol
, vol.4
, pp. 248-254
-
-
Stefanová, I.1
Hemmer, B.2
Vergelli, M.3
Martin, R.4
Biddison, W.E.5
Germain, R.N.6
-
44
-
-
38449086723
-
CD8+ T cell activation is governed by TCR-Peptide/MHC affinity, not dissociation rate
-
Tian S, Maile R, Collins EJ, Frelinger JA. 2007. CD8+ T cell activation is governed by TCR-Peptide/MHC affinity, not dissociation rate. J Immunol 179:2952-60.
-
(2007)
J Immunol
, vol.179
, pp. 2952-2960
-
-
Tian, S.1
Maile, R.2
Collins, E.J.3
Frelinger, J.A.4
-
45
-
-
0029037210
-
Serial triggering of many T-cell receptors by a few peptide-MHC complexes
-
doi: 10.1038/375148a0
-
Valitutti S, Muller S, Cella M, Padovan E, Lanzavecchia A. 1995. Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature 375:148-51. doi: 10.1038/375148a0.
-
(1995)
Nature
, vol.375
, pp. 148-151
-
-
Valitutti, S.1
Muller, S.2
Cella, M.3
Padovan, E.4
Lanzavecchia, A.5
-
46
-
-
78650599246
-
Mechanisms for T cell receptor triggering
-
doi: 10.1038/nri2887
-
Van der Merwe PA, Dushek O. 2011. Mechanisms for T cell receptor triggering. Nat Rev Immunol 11:47-55. doi: 10.1038/nri2887.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 47-55
-
-
Van der Merwe, P.A.1
Dushek, O.2
-
47
-
-
33746011209
-
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster
-
doi: 10.1016/j.immuni.2006.04.010
-
Varma R, Campi G, Yokosuka T, Saito T, Dustin ML. 2006. T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster. Immunity 25:117-27. doi: 10.1016/j.immuni.2006.04.010.
-
(2006)
Immunity
, vol.25
, pp. 117-127
-
-
Varma, R.1
Campi, G.2
Yokosuka, T.3
Saito, T.4
Dustin, M.L.5
-
48
-
-
0028014460
-
Signal transduction by lymphocyte antigen receptors
-
doi: 10.1016/0092-8674(94)90334-4
-
Weiss A, Littman DR. 1994. Signal transduction by lymphocyte antigen receptors. Cell 76:263-74. doi: 10.1016/0092-8674(94)90334-4.
-
(1994)
Cell
, vol.76
, pp. 263-274
-
-
Weiss, A.1
Littman, D.R.2
-
49
-
-
0033577859
-
A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex
-
doi: 10.1084/jem.189.10.1531
-
Williams CB, Engle DL, Kersh GJ, Michael White J, Allen PM. 1999. A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex. J Exp Med 189:1531-44. doi: 10.1084/jem.189.10.1531.
-
(1999)
J Exp Med
, vol.189
, pp. 1531-1544
-
-
Williams, C.B.1
Engle, D.L.2
Kersh, G.J.3
Michael White, J.4
Allen, P.M.5
-
50
-
-
82955240504
-
EphA2 receptor activation by monomeric Ephrin-A1 on supported membranes
-
doi: 10.1016/j.bpj.2011.10.039
-
Xu Q, Lin WC, Petit RS, Groves JT. 2011. EphA2 receptor activation by monomeric Ephrin-A1 on supported membranes. Biophys J 101:2731-9. doi: 10.1016/j.bpj.2011.10.039.
-
(2011)
Biophys J
, vol.101
, pp. 2731-2739
-
-
Xu, Q.1
Lin, W.C.2
Petit, R.S.3
Groves, J.T.4
-
51
-
-
84859470532
-
Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4
-
doi: 10.1073/pnas.1118801109
-
Yin Y, Wang XX, Mariuzza RA. 2012. Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4. Proc Natl Acad Sci USA 109:5405-10. doi: 10.1073/pnas.1118801109.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 5405-5410
-
-
Yin, Y.1
Wang, X.X.2
Mariuzza, R.A.3
-
52
-
-
30044441433
-
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76
-
doi: 10.1038/ni1272
-
Yokosuka T, Sakata-Sogawa K, Kobayashi W, Hiroshima M, Hashimoto-Tane A, Tokunaga M, et al. 2005. Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76. Nat Immunol 6:1253-62. doi: 10.1038/ni1272.
-
(2005)
Nat Immunol
, vol.6
, pp. 1253-1262
-
-
Yokosuka, T.1
Sakata-Sogawa, K.2
Kobayashi, W.3
Hiroshima, M.4
Hashimoto-Tane, A.5
Tokunaga, M.6
-
53
-
-
84863040809
-
Myosin IIA modulates T cell receptor transport and CasL phosphorylation during early immunological synapse formation
-
doi: 10.1371/journal.pone.0030704
-
Yu Y, Fay NC, Smoligovets AA, Wu HJ, Groves JT. 2012. Myosin IIA modulates T cell receptor transport and CasL phosphorylation during early immunological synapse formation. PLOS ONE 7:e30704. doi: 10.1371/journal.pone.0030704.
-
(2012)
PLOS ONE
, vol.7
-
-
Yu, Y.1
Fay, N.C.2
Smoligovets, A.A.3
Wu, H.J.4
Groves, J.T.5
-
54
-
-
84871447669
-
Insights from in situ analysis of TCR-pMHC recognition: Response of an interaction network
-
doi: 10.1111/imr.12016
-
Zhu C, Jiang N, Huang J, Zarnitsyna VI, Evavold BD. 2013. Insights from in situ analysis of TCR-pMHC recognition: response of an interaction network. Immunol Rev 251:49-64. doi: 10.1111/imr.12016.
-
(2013)
Immunol Rev
, vol.251
, pp. 49-64
-
-
Zhu, C.1
Jiang, N.2
Huang, J.3
Zarnitsyna, V.I.4
Evavold, B.D.5
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