The CD3 ζ subunit contains a phosphoinositide-binding motif that is required for the stable accumulation of TCR-CD3 complex at the immunological synapse

Journal of Immunology

Volumn 186, Issue 12, 2011, Pages 6839-6847

  DeFord Watts, Laura M ^a   Dougall, David S ^a   Belkaya, Serkan ^a   Johnson, Blake A ^a   Eitson, Jennifer L ^a   Roybal, Kole T ^a   Barylko, Barbara ^b   Albanesi, Joseph P ^b   Wülfing, Christoph ^a   Van Oers, Nicolai S C ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; CD3 ANTIGEN; CD3 ZETA ANTIGEN; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,5 DIPHOSPHATE; PHOSPHATIDYLINOSITOL 4 PHOSPHATE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANTIGEN PRESENTING CELL; ARTICLE; BINDING AFFINITY; BIOACCUMULATION; CELL INTERACTION; CELL STRUCTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN STABILITY; PROTEIN VARIANT; SIGNAL TRANSDUCTION; SYNAPSE; T LYMPHOCYTE ACTIVATION;

AMINO ACIDS, BASIC; ANIMALS; ANTIGENS, CD3; BINDING SITES; CELL LINE; HUMANS; IMMUNOLOGICAL SYNAPSES; LYMPHOCYTE ACTIVATION; MICE; PHOSPHATIDYLINOSITOLS; PROTEIN BINDING; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 79959542722     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1002721     Document Type: Article

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