Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC

Journal of Experimental Medicine

Volumn 210, Issue 9, 2013, Pages 1807-1821

  Hoerter, John A H ^a   Brzostek, Joanna ^a   Artyomov, Maxim N ^f   Abel, Steven M ^c,d   Casas, Javier ^a   Rybakin, Vasily ^a   Ampudia, Jeanette ^a   Lotz, Carina ^a   Connolly, Janet M ^g   Chakraborty, Arup K ^c,d,e   Gould, Keith G ^b   Gascoigne, Nicholas R J ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c Department of Chemical Engineering ^*  (United Kingdom)

^d Massachusetts Institute of Technology Cambridge   (United Kingdom)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^f BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^g WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN SPECIFICITY; ARTICLE; BINDING AFFINITY; COMPUTER SIMULATION; CONTROLLED STUDY; GENE EXPRESSION SYSTEM; LIGAND BINDING; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; T LYMPHOCYTE ACTIVATION;

AMINO ACID SEQUENCE; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CHO CELLS; COMPUTER SIMULATION; CRICETINAE; CRICETULUS; EPITOPES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; KINETICS; LYMPHOCYTE ACTIVATION; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OVALBUMIN; PEPTIDES; PROTEIN BINDING; RECEPTORS, ANTIGEN, T-CELL;

EID: 84884220136     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20122528     Document Type: Article

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