The ability of sos1 to oligomerize the adaptor protein lat is separable from its guanine nucleotide exchange activity in vivo

Science Signaling

Volumn 6, Issue 301, 2013, Pages

  Kortum, Robert L ^a   Balagopalan, Lakshmi ^a   Alexander, Clayton P ^a   Garcia, Julie ^a   Pinski, John M ^a   Merrill, Robert K ^a   Nguyen, Phan H ^a   Li, Wenmei ^a   Agarwal, Isha ^a   Akpan, Itoro O ^a   Sommers, Connie L ^a   Samelson, Lawrence E ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; GUANINE NUCLEOTIDE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; LAT PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE C GAMMA1; PROTEIN KINASE ZAP 70; RAS PROTEIN; SOS PROTEIN; T LYMPHOCYTE RECEPTOR; GRB2 PROTEIN, MOUSE; LAT PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NUCLEOTIDE; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM SIGNALING; CELL MATURATION; CELL PROLIFERATION; CELL SELECTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; IN VIVO STUDY; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; T LYMPHOCYTE; THYMOCYTE; TRANSGENICS; ANIMAL; CELL DIFFERENTIATION; CHEMISTRY; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSGENE; TRANSGENIC MOUSE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CALCIUM SIGNALING; CELL DIFFERENTIATION; CELL PROLIFERATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; GRB2 ADAPTOR PROTEIN; MALE; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MUTATION; NUCLEOTIDES; PHOSPHOPROTEINS; PHOSPHORYLATION; RAS PROTEINS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SOS1 PROTEIN; T-LYMPHOCYTES; THYMOCYTES; TRANSGENES;

EID: 84888093616     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2004494     Document Type: Article

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