Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling

Nature Immunology

Volumn 15, Issue 2, 2014, Pages 186-194

  Tan, Ying Xim ^a   Manz, Boryana N ^a   Freedman, Tanya S ^a   Zhang, Chao ^b   Shokat, Kevan M ^a,c   Weiss, Arthur ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ACTIN; CD28 ANTIGEN; INOSITOL PHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C GAMMA1; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CYTOSKELETON; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; THYMOCYTE;

ACTINS; ANIMALS; ANTIGENS, CD28; CELLS, CULTURED; CYTOCHALASIN D; CYTOSKELETON; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTANT PROTEINS; POLYMERIZATION; PROTEIN ENGINEERING; PYRAZOLES; PYRIMIDINES; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; THYMOCYTES;

EID: 84892719664     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2772     Document Type: Article

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