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Volumn 22, Issue 7, 2015, Pages 866-877

P2X receptors and inflammation

Author keywords

Extracellular ATP; Innate immunity; P2X4; P2X7; Purinergic receptors

Indexed keywords

AMYLOID BETA PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE 3; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CRYOPYRIN; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 2; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PHOSPHOLIPASE A2; PHOSPHOLIPASE C; PHOSPHOLIPASE D; PURINERGIC P2X RECEPTOR; PURINERGIC P2X1 RECEPTOR; PURINERGIC P2X2 RECEPTOR; PURINERGIC P2X3 RECEPTOR; PURINERGIC P2X4 RECEPTOR; PURINERGIC P2X5 RECEPTOR; PURINERGIC P2X6 RECEPTOR; PURINERGIC P2X7 RECEPTOR; SERUM AMYLOID A; TOLL LIKE RECEPTOR; VASCULOTROPIN;

EID: 84926471604     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/0929867322666141210155311     Document Type: Article
Times cited : (69)

References (162)
  • 1
    • 34248576759 scopus 로고    scopus 로고
    • Physiology and pathophysiology of purinergic neurotransmission
    • Burnstock, G. Physiology and pathophysiology of purinergic neurotransmission. Physiol. Rev., 2007, 87, 659-797
    • (2007) Physiol. Rev. , vol.87 , pp. 659-797
    • Burnstock, G.1
  • 3
    • 51049101334 scopus 로고    scopus 로고
    • Adenosine receptors, therapeutic aspects for inflammatory and immune diseases
    • Hasko, G.; Linden, J.; Cronstein, B.; Pacher, P. Adenosine receptors, therapeutic aspects for inflammatory and immune diseases. Nat. Rev. Drug Discov., 2008, 7, 759-770
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 759-770
    • Hasko, G.1    Linden, J.2    Cronstein, B.3    Pacher, P.4
  • 4
    • 50249085890 scopus 로고    scopus 로고
    • Increased level of extracellular ATP at tumor sites, in vivo imaging with plasma membrane luciferase
    • Pellegatti, P.; Raffaghello, L.; Bianchi, G.; Piccardi, F.; Pistoia, V.; Di Virgilio, F. Increased level of extracellular ATP at tumor sites, in vivo imaging with plasma membrane luciferase. PLoS ONE, 2008, 3, e2599
    • (2008) PLoS ONE , vol.3 , pp. e2599
    • Pellegatti, P.1    Raffaghello, L.2    Bianchi, G.3    Piccardi, F.4    Pistoia, V.5    Di Virgilio, F.6
  • 5
    • 84876558170 scopus 로고    scopus 로고
    • Detecting adenosine triphosphate in the pericellular space
    • 2012.0101
    • Falzoni, S.; Donvito, G.; Di Virgilio, F. Detecting adenosine triphosphate in the pericellular space. Interface Focus, 2013, 3, 2012.0101
    • (2013) Interface Focus , vol.3
    • Falzoni, S.1    Donvito, G.2    Di Virgilio, F.3
  • 7
    • 79952192382 scopus 로고    scopus 로고
    • Immune cell regulation by autocrine purinergic signalling
    • Junger, W.G. Immune cell regulation by autocrine purinergic signalling. Nat. Rev. Immunol., 2011, 11, 201-212
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 201-212
    • Junger, W.G.1
  • 8
    • 84900530332 scopus 로고    scopus 로고
    • Nucleotide signalling during inflammation
    • Idzko, M.; Ferrari, D.; Eltzschig, H.K. Nucleotide signalling during inflammation. Nature, 2014, 509, 310-317
    • (2014) Nature , vol.509 , pp. 310-317
    • Idzko, M.1    Ferrari, D.2    Eltzschig, H.K.3
  • 9
    • 0030249877 scopus 로고    scopus 로고
    • The involvement of an ATP-gated ion channel; P(2X1); in thymocyte apoptosis
    • Chvatchko, Y.; Valera, S.; Aubry, J.P.; Renno, T.; Buell, G.; Bonnefoy, J.Y. The involvement of an ATP-gated ion channel; P(2X1); in thymocyte apoptosis. Immunity, 1996, 5, 275-283
    • (1996) Immunity , vol.5 , pp. 275-283
    • Chvatchko, Y.1    Valera, S.2    Aubry, J.P.3    Renno, T.4    Buell, G.5    Bonnefoy, J.Y.6
  • 10
    • 78149326486 scopus 로고    scopus 로고
    • Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse
    • Woehrle, T.; Yip, L.; Elkhal, A.; Sumi, Y.; Chen, Y.; Yao, Y.; Insel, P.A.; Junger, W.G. Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse. Blood, 2010, 116, 3475-3484
    • (2010) Blood , vol.116 , pp. 3475-3484
    • Woehrle, T.1    Yip, L.2    Elkhal, A.3    Sumi, Y.4    Chen, Y.5    Yao, Y.6    Insel, P.A.7    Junger, W.G.8
  • 11
    • 77954886436 scopus 로고    scopus 로고
    • P2X4 receptors mediate PGE2 release by tissue-resident macrophages and initiate inflammatory pain
    • Ulmann, L.; Hirbec, H.; Rassendren, F. P2X4 receptors mediate PGE2 release by tissue-resident macrophages and initiate inflammatory pain. EMBO J., 2010, 29, 2290-2300
    • (2010) EMBO J. , vol.29 , pp. 2290-2300
    • Ulmann, L.1    Hirbec, H.2    Rassendren, F.3
  • 14
    • 84864487226 scopus 로고    scopus 로고
    • P2X4R+ microglia drive neuropathic pain
    • Beggs, S.; Trang, T.; Salter, M.W. P2X4R+ microglia drive neuropathic pain. Nat. Neurosci., 2012, 15, 1068-1073
    • (2012) Nat. Neurosci. , vol.15 , pp. 1068-1073
    • Beggs, S.1    Trang, T.2    Salter, M.W.3
  • 16
    • 84864765533 scopus 로고    scopus 로고
    • Microglia and mast cells, two tracks on the road to neuroinflammation
    • Skaper, S.D.; Giusti, P.; Facci L. Microglia and mast cells, two tracks on the road to neuroinflammation. FASEB J., 2014, 26, 3103-3117
    • (2014) FASEB J. , vol.26 , pp. 3103-3117
    • Skaper, S.D.1    Giusti, P.2    Facci, L.3
  • 18
    • 0028175838 scopus 로고
    • Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity
    • Perregaux, D.; Gabel, C.A. Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. J. Biol. Chem., 1994, 269, 15195-15203
    • (1994) J. Biol. Chem. , vol.269 , pp. 15195-15203
    • Perregaux, D.1    Gabel, C.A.2
  • 19
    • 0034192082 scopus 로고    scopus 로고
    • Kinetics and mechanism of ATPdependent IL-1 beta release from microglial cells
    • Sanz J.M.; Di Virgilio, F. Kinetics and mechanism of ATPdependent IL-1 beta release from microglial cells. J. Immunol., 2000, 164, 4893-4898
    • (2000) J. Immunol. , vol.164 , pp. 4893-4898
    • Sanz, J.M.1    Di Virgilio, F.2
  • 20
    • 84879596906 scopus 로고    scopus 로고
    • K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter
    • Munoz-Planillo, R.; Kuffa, P.; Martinez-Colon, G.; Smith, B.L.; Rajendiran, T.M.; Nunez, G. K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. Immunity, 2013, 38, 1142-1153
    • (2013) Immunity , vol.38 , pp. 1142-1153
    • Munoz-Planillo, R.1    Kuffa, P.2    Martinez-Colon, G.3    Smith, B.L.4    Rajendiran, T.M.5    Nunez, G.6
  • 25
    • 70350347701 scopus 로고    scopus 로고
    • Functional evidence for the expression of P2X1; P2X4 and P2X7 receptors in human lung mast cells
    • Wareham, K.; Vial, C.; Wykes, R.C.; Bradding, P.; Seward, E.P. Functional evidence for the expression of P2X1; P2X4 and P2X7 receptors in human lung mast cells. Br. J. Pharmacol., 2009, 157, 1215-1224
    • (2009) Br. J. Pharmacol. , vol.157 , pp. 1215-1224
    • Wareham, K.1    Vial, C.2    Wykes, R.C.3    Bradding, P.4    Seward, E.P.5
  • 26
    • 77950460129 scopus 로고    scopus 로고
    • P2 receptor-mediated signaling in mast cell biology
    • Bulanova, E.; Bulfone-Paus, S. P2 receptor-mediated signaling in mast cell biology. Purinergic Signal., 2010, 6, 3-17
    • (2010) Purinergic Signal. , vol.6 , pp. 3-17
    • Bulanova, E.1    Bulfone-Paus, S.2
  • 27
    • 0018911238 scopus 로고
    • The ATP4-receptor of rat mast cells
    • Cockcroft, S.; Gomperts, B.D. The ATP4-receptor of rat mast cells. Biochem. J., 1980, 188, 789-798
    • (1980) Biochem. J. , vol.188 , pp. 789-798
    • Cockcroft, S.1    Gomperts, B.D.2
  • 28
    • 46449134214 scopus 로고    scopus 로고
    • Purinergic signalling and disorders of the central nervous system
    • Burnstock, G. Purinergic signalling and disorders of the central nervous system. Nat. Rev. Drug Discov., 2008, 7, 575-590
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 575-590
    • Burnstock, G.1
  • 29
    • 53049107855 scopus 로고    scopus 로고
    • Purinergic systems in microglia
    • Inoue, K. Purinergic systems in microglia. Cell. Mol. Life Sci., 2008, 65, 3074-3080
    • (2008) Cell. Mol. Life Sci. , vol.65 , pp. 3074-3080
    • Inoue, K.1
  • 30
    • 84891133400 scopus 로고    scopus 로고
    • Purinergic signaling and blood vessels in health and disease
    • Burnstock, G.; Ralevic, V. Purinergic signaling and blood vessels in health and disease. Pharmacol. Rev., 2014, 66, 102-192
    • (2014) Pharmacol. Rev. , vol.66 , pp. 102-192
    • Burnstock, G.1    Ralevic, V.2
  • 31
    • 77951286052 scopus 로고    scopus 로고
    • The P2X1 ion channel in platelet function
    • Hu, H.; Hoylaerts, M.F. The P2X1 ion channel in platelet function. Platelets, 2010, 21, 153-166
    • (2010) Platelets , vol.21 , pp. 153-166
    • Hu, H.1    Hoylaerts, M.F.2
  • 32
    • 84908232996 scopus 로고    scopus 로고
    • The P2X7 receptor channel, recent developments and the use of P2X7 antagonists in models of disease
    • Bartlett, R.; Stokes, L.; Sluyter, R. The P2X7 receptor channel, recent developments and the use of P2X7 antagonists in models of disease. Pharmacol. Rev., 2014, 66, 638-675
    • (2014) Pharmacol. Rev. , vol.66 , pp. 638-675
    • Bartlett, R.1    Stokes, L.2    Sluyter, R.3
  • 39
    • 33745188916 scopus 로고    scopus 로고
    • A truncated P2X7 receptor variant (P2X7-j) endogenously expressed in cervical cancer cells antagonizes the full-length P2X7 receptor through hetero-oligomerization
    • Feng, Y.H.; Li, X.; Wang, L.; Zhou, L.; Gorodeski, G.I. A truncated P2X7 receptor variant (P2X7-j) endogenously expressed in cervical cancer cells antagonizes the full-length P2X7 receptor through hetero-oligomerization. J. Biol. Chem., 2006, 281, 17228-17237
    • (2006) J. Biol. Chem. , vol.281 , pp. 17228-17237
    • Feng, Y.H.1    Li, X.2    Wang, L.3    Zhou, L.4    Gorodeski, G.I.5
  • 43
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • Medzhitov, R. Origin and physiological roles of inflammation. Nature, 2008, 454, 428-435
    • (2008) Nature , vol.454 , pp. 428-435
    • Medzhitov, R.1
  • 44
    • 84876350807 scopus 로고    scopus 로고
    • The therapeutic potential of modifying inflammasomes and NOD-like receptors
    • Di Virgilio, F. The therapeutic potential of modifying inflammasomes and NOD-like receptors. Pharmacol. Rev., 2013, 65, 872-905
    • (2013) Pharmacol. Rev. , vol.65 , pp. 872-905
    • Di Virgilio, F.1
  • 45
    • 84862301337 scopus 로고    scopus 로고
    • Current status of inflammasome blockers as anti-inflammatory drugs
    • Lopez-Castejon, G.; Pelegrin, P. Current status of inflammasome blockers as anti-inflammatory drugs. Expert. Opin. Investig. Drugs, 2012, 21, 995-1007
    • (2012) Expert. Opin. Investig. Drugs , vol.21 , pp. 995-1007
    • Lopez-Castejon, G.1    Pelegrin, P.2
  • 46
    • 0036788971 scopus 로고    scopus 로고
    • Molecular physiology of P2X receptors
    • North, R.A. Molecular physiology of P2X receptors. Physiol. Rev., 2002, 82, 1013-1067
    • (2002) Physiol. Rev. , vol.82 , pp. 1013-1067
    • North, R.A.1
  • 49
    • 1842581655 scopus 로고    scopus 로고
    • A novel P2X7 receptor activator; The human cathelicidin-derived peptide LL37; Induces IL-1 beta processing and release
    • Elssner, A.; Duncan, M.; Gavrilin, M.; Wewers, M.D. A novel P2X7 receptor activator; the human cathelicidin-derived peptide LL37; induces IL-1 beta processing and release. J. Immunol., 2004, 172, 4987-4994
    • (2004) J. Immunol. , vol.172 , pp. 4987-4994
    • Elssner, A.1    Duncan, M.2    Gavrilin, M.3    Wewers, M.D.4
  • 51
    • 0034683668 scopus 로고    scopus 로고
    • Cell to cell communication in response to mechanical stress via bilateral release of ATP and UTP in polarized epithelia
    • Homolya, L.; Steinberg, T.H.; Boucher, R.C. Cell to Cell Communication in Response to Mechanical Stress via Bilateral Release of ATP and UTP in Polarized Epithelia. J. Cell Biol., 2000, 150, 1349-1360
    • (2000) J. Cell Biol. , vol.150 , pp. 1349-1360
    • Homolya, L.1    Steinberg, T.H.2    Boucher, R.C.3
  • 52
    • 77749292135 scopus 로고    scopus 로고
    • Shockwaves increase T-cell proliferation and IL-2 expression through ATP release; P2X7 receptors; And FAK activation
    • Yu, T.; Junger, W.G.; Yuan, C.; Jin, A.; Zhao, Y.; Zheng, X.; Zeng, Y.; Liu, J. Shockwaves increase T-cell proliferation and IL-2 expression through ATP release; P2X7 receptors; and FAK activation. Am. J. Physiol. Cell. Physiol., 2010, 298, C457-C464
    • (2010) Am. J. Physiol. Cell. Physiol. , vol.298 , pp. C457-C464
    • Yu, T.1    Junger, W.G.2    Yuan, C.3    Jin, A.4    Zhao, Y.5    Zheng, X.6    Zeng, Y.7    Liu, J.8
  • 57
    • 84874994660 scopus 로고    scopus 로고
    • P2X4 receptor regulates P2X7 receptor-dependent IL-1beta and IL-18 release in mouse bone marrow-derived dendritic cells
    • Sakaki, H.; Fujiwaki, T.; Tsukimoto, M.; Kawano, A.; Harada, H.; Kojima, S. P2X4 receptor regulates P2X7 receptor-dependent IL-1beta and IL-18 release in mouse bone marrow-derived dendritic cells. Biochem. Biophys. Res. Commun., 2013, 432, 406-411
    • (2013) Biochem. Biophys. Res. Commun. , vol.432 , pp. 406-411
    • Sakaki, H.1    Fujiwaki, T.2    Tsukimoto, M.3    Kawano, A.4    Harada, H.5    Kojima, S.6
  • 59
    • 0029665112 scopus 로고    scopus 로고
    • The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)
    • Surprenant, A.; Rassendren, F.; Kawashima, E.; North, R.A.; Buell, G. The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science, 1996, 272, 735-738
    • (1996) Science , vol.272 , pp. 735-738
    • Surprenant, A.1    Rassendren, F.2    Kawashima, E.3    North, R.A.4    Buell, G.5
  • 61
  • 62
    • 0034667943 scopus 로고    scopus 로고
    • ATP Acts as an Agonist to Promote Stimulus-Induced Secretion of IL-1{beta} and IL-18 in Human Blood
    • Perregaux, D.G.; McNiff, P.; Laliberte, R.; Conklyn, M.; Gabel, C.A. ATP Acts as an Agonist to Promote Stimulus-Induced Secretion of IL-1{beta} and IL-18 in Human Blood. J. Immunol., 2000, 165, 4615-4623
    • (2000) J. Immunol. , vol.165 , pp. 4615-4623
    • Perregaux, D.G.1    McNiff, P.2    Laliberte, R.3    Conklyn, M.4    Gabel, C.A.5
  • 63
    • 0035830853 scopus 로고    scopus 로고
    • ATP-stimulated release of interleukin (IL)-1 beta and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage
    • Mehta, V.B.; Hart, J.; Wewers, M.D. ATP-stimulated release of interleukin (IL)-1 beta and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage. J. Biol. Chem., 2001, 276, 3820-3826
    • (2001) J. Biol. Chem. , vol.276 , pp. 3820-3826
    • Mehta, V.B.1    Hart, J.2    Wewers, M.D.3
  • 64
    • 47249144272 scopus 로고    scopus 로고
    • P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage
    • Pelegrin, P.; Barroso-Gutierrez, C.; Surprenant, A. P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage. J. Immunol., 2008, 180, 7147-7157
    • (2008) J. Immunol. , vol.180 , pp. 7147-7157
    • Pelegrin, P.1    Barroso-Gutierrez, C.2    Surprenant, A.3
  • 65
    • 0033066921 scopus 로고    scopus 로고
    • Human primary fibroblasts in vitro express a purinergic P2X7 receptor coupled to ion fluxes; Microvesicle formation and IL-6 release
    • Solini, A.; Chiozzi, P.; Morelli, A.; Fellin, R.; Di Virgilio, F. Human primary fibroblasts in vitro express a purinergic P2X7 receptor coupled to ion fluxes; microvesicle formation and IL-6 release. J. Cell Sci., 1999, 112( Pt 3), 297-305
    • (1999) J. Cell Sci. , vol.112 , pp. 297-305
    • Solini, A.1    Chiozzi, P.2    Morelli, A.3    Fellin, R.4    Di Virgilio, F.5
  • 67
    • 82955233684 scopus 로고    scopus 로고
    • Adipocyte P2X7 receptors expression, a role in modulating inflammatory response in subjects with metabolic syndrome?
    • Madec, S.; Rossi, C.; Chiarugi, M.; Santini, E.; Salvati, A.; Ferrannini, E.; Solini, A. Adipocyte P2X7 receptors expression, a role in modulating inflammatory response in subjects with metabolic syndrome? Atherosclerosis, 2011, 219, 552-558
    • (2011) Atherosclerosis , vol.219 , pp. 552-558
    • Madec, S.1    Rossi, C.2    Chiarugi, M.3    Santini, E.4    Salvati, A.5    Ferrannini, E.6    Solini, A.7
  • 68
    • 84893739709 scopus 로고    scopus 로고
    • P2X7-dependent but differentially regulated release of IL-6; CCL2; and TNF-alpha in cultured mouse microglia
    • Shieh, C.H.; Heinrich, A.; Serchov, T.; van Calker, D.; Biber, K. P2X7-dependent, but differentially regulated release of IL-6; CCL2; and TNF-alpha in cultured mouse microglia. Glia, 2014, 62, 592-607
    • (2014) Glia , vol.62 , pp. 592-607
    • Shieh, C.H.1    Heinrich, A.2    Serchov, T.3    Van Calker, D.4    Biber, K.5
  • 70
    • 0038475924 scopus 로고    scopus 로고
    • Hypertonic stress increases T cell interleukin-2 expression through a mechanism that involves ATP release; P2 receptor; And p38 MAPK activation
    • Loomis, W.H.; Namiki, S.; Ostrom, R.S.; Insel, P.A.; Junger, W.G. Hypertonic stress increases T cell interleukin-2 expression through a mechanism that involves ATP release; P2 receptor; and p38 MAPK activation. J. Biol. Chem., 2003, 278, 4590-4596
    • (2003) J. Biol. Chem. , vol.278 , pp. 4590-4596
    • Loomis, W.H.1    Namiki, S.2    Ostrom, R.S.3    Insel, P.A.4    Junger, W.G.5
  • 71
  • 75
    • 84906075907 scopus 로고    scopus 로고
    • A negative feedback loop mediated by stat3 limits human th17 responses
    • Purvis, H.A.; Anderson, A.E.; Young, D.A.; Isaacs, J.D.; Hilkens, C.M. A Negative Feedback Loop Mediated by STAT3 Limits Human Th17 Responses. J. Immunol., 2014, 193, 1142-1150
    • (2014) J. Immunol. , vol.193 , pp. 1142-1150
    • Purvis, H.A.1    Anderson, A.E.2    Young, D.A.3    Isaacs, J.D.4    Hilkens, C.M.5
  • 76
    • 0035884937 scopus 로고    scopus 로고
    • P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase
    • Panenka, W.; Jijon, H.; Herx, L.M.; Armstrong, J.N.; Feighan, D.; Wei, T.; Yong, V.W.; Ransohoff, R.M.; MacVicar B.A. P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase. J. Neurosci., 2001, 21, 7135-7142
    • (2001) J. Neurosci. , vol.21 , pp. 7135-7142
    • Panenka, W.1    Jijon, H.2    Herx, L.M.3    Armstrong, J.N.4    Feighan, D.5    Wei, T.6    Yong, V.W.7    Ransohoff, R.M.8    Macvicar, B.A.9
  • 77
    • 38449104014 scopus 로고    scopus 로고
    • Purinergic P2Y2 receptors induce increased MCP-1/CCL2 synthesis and release from rat alveolar and peritoneal macrophages
    • Stokes, L.; Surprenant, A. Purinergic P2Y2 Receptors Induce Increased MCP-1/CCL2 Synthesis and Release from Rat Alveolar and Peritoneal Macrophages. J. Immunol., 2007, 179, 6016-6023
    • (2007) J. Immunol. , vol.179 , pp. 6016-6023
    • Stokes, L.1    Surprenant, A.2
  • 78
    • 57249111810 scopus 로고    scopus 로고
    • Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT
    • Kataoka, A.; Tozaki-Saitoh, H.; Koga, Y.; Tsuda, M.; Inoue, K. Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT. J. Neurochem., 2009, 108, 115-125
    • (2009) J. Neurochem. , vol.108 , pp. 115-125
    • Kataoka, A.1    Tozaki-Saitoh, H.2    Koga, Y.3    Tsuda, M.4    Inoue, K.5
  • 79
    • 84907421651 scopus 로고    scopus 로고
    • Expression of P2X7 ATP receptor mediating the IL8 and CCL20 release in human periodontal ligament stem cells
    • Trubiani, O.; Horenstein, A.L.; Caciagli, F.; Caputi, S.; Malavasi, F.; Ballerini, P. Expression of P2X7 ATP receptor mediating the IL8 and CCL20 release in human periodontal ligament stem cells. J. Cell Biochem., 2014, 115, 1138-1146
    • (2014) J. Cell Biochem. , vol.115 , pp. 1138-1146
    • Trubiani, O.1    Horenstein, A.L.2    Caciagli, F.3    Caputi, S.4    Malavasi, F.5    Ballerini, P.6
  • 80
    • 0142027030 scopus 로고    scopus 로고
    • Activation of P2X7 purinoceptor-stimulated TGF-beta 1 mRNA expression involves PKC/MAPK signalling pathway in a rat brain-derived type-2 astrocyte cell line; RBA-2
    • Wang, C.M.; Chang, Y.Y.; Sun, S.H. Activation of P2X7 purinoceptor-stimulated TGF-beta 1 mRNA expression involves PKC/MAPK signalling pathway in a rat brain-derived type-2 astrocyte cell line; RBA-2. Cell Signal., 2003, 15, 1129-1137
    • (2003) Cell Signal. , vol.15 , pp. 1129-1137
    • Wang, C.M.1    Chang, Y.Y.2    Sun, S.H.3
  • 84
    • 78049404838 scopus 로고    scopus 로고
    • Extracellular ATP may contribute to tissue repair by rapidly stimulating purinergic receptor X7-dependent vascular endothelial growth factor release from primary human monocytes
    • Hill, L.M.; Gavala, M.L.; Lenertz, L.Y.; Bertics, P.J. Extracellular ATP may contribute to tissue repair by rapidly stimulating purinergic receptor X7-dependent vascular endothelial growth factor release from primary human monocytes. J. Immunol., 2010, 185, 3028-3034
    • (2010) J. Immunol. , vol.185 , pp. 3028-3034
    • Hill, L.M.1    Gavala, M.L.2    Lenertz, L.Y.3    Bertics, P.J.4
  • 86
    • 4143136640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor, basic science and clinical progress
    • Ferrara, N. Vascular Endothelial Growth Factor, Basic Science and Clinical Progress. Endocr. Rev., 2004, 25, 581-611
    • (2004) Endocr. Rev. , vol.25 , pp. 581-611
    • Ferrara, N.1
  • 88
    • 84897560418 scopus 로고    scopus 로고
    • Recent developments in the treatment of age-related macular degeneration
    • Holz, F.G.; Schmitz-Valckenberg, S.; Fleckenstein, M. Recent developments in the treatment of age-related macular degeneration. J. Clin. Invest., 2014, 124, 1430-1438
    • (2014) J. Clin. Invest. , vol.124 , pp. 1430-1438
    • Holz, F.G.1    Schmitz-Valckenberg, S.2    Fleckenstein, M.3
  • 89
    • 0031425953 scopus 로고    scopus 로고
    • Extracellular ATP activates transcription factor NF-kappa B through the P2Z purinoreceptor by selectively targeting NF-kappa B p65
    • Ferrari, D.; Wesselborg, S.; Bauer, M.K.; Schulze-Osthoff, K. Extracellular ATP activates transcription factor NF-kappa B through the P2Z purinoreceptor by selectively targeting NF-kappa B p65. J. Cell Biol., 1997, 139, 1635-1643
    • (1997) J. Cell Biol. , vol.139 , pp. 1635-1643
    • Ferrari, D.1    Wesselborg, S.2    Bauer, M.K.3    Schulze-Osthoff, K.4
  • 90
    • 0033531791 scopus 로고    scopus 로고
    • P2X7/P2Z purinoreceptor-mediated activation of transcription factor NFAT in microglial cells
    • Ferrari, D.; Stroh, C.; Schulze-Osthoff, K. P2X7/P2Z purinoreceptor-mediated activation of transcription factor NFAT in microglial cells. J. Biol. Chem., 1999, 274, 13205-13210
    • (1999) J. Biol. Chem. , vol.274 , pp. 13205-13210
    • Ferrari, D.1    Stroh, C.2    Schulze-Osthoff, K.3
  • 91
    • 65649141604 scopus 로고    scopus 로고
    • Expression of the P2X7 receptor increases the Ca2+ content of the endoplasmic reticulum; Activates NFATc1 and protects from apoptosis
    • Adinolfi, E.; Callegari, M.G.; Cirillo, M.; Pinton, P.; Giorgi, C.; Cavagna, D.; Rizzuto, R.; Di Virgilio, F. Expression of the P2X7 receptor increases the Ca2+ content of the endoplasmic reticulum; activates NFATc1 and protects from apoptosis. J. Biol. Chem., 2009, 284, 10120-10128
    • (2009) J. Biol. Chem. , vol.284 , pp. 10120-10128
    • Adinolfi, E.1    Callegari, M.G.2    Cirillo, M.3    Pinton, P.4    Giorgi, C.5    Cavagna, D.6    Rizzuto, R.7    Di Virgilio, F.8
  • 93
    • 79961174606 scopus 로고    scopus 로고
    • Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-{kappa}B
    • Tafani, M.; Schito, L.; Pellegrini, L.; Villanova, L.; Marfe, G.; Anwar, T.; Rosa, R.; Indelicato, M.; Fini, M.; Pucci, B.; Russo, M.A. Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-{kappa}B. Carcinogenesis, 2011, 32, 1167-1175
    • (2011) Carcinogenesis , vol.32 , pp. 1167-1175
    • Tafani, M.1    Schito, L.2    Pellegrini, L.3    Villanova, L.4    Marfe, G.5    Anwar, T.6    Rosa, R.7    Indelicato, M.8    Fini, M.9    Pucci, B.10    Russo, M.A.11
  • 95
    • 3142757912 scopus 로고    scopus 로고
    • Secretion of intracellular IL-1 receptor antagonist (type 1) is dependent on P2X7 receptor activation
    • Wilson, H.L.; Francis, S.E.; Dower, S.K.; Crossman, D.C. Secretion of intracellular IL-1 receptor antagonist (type 1) is dependent on P2X7 receptor activation. J. Immunol., 2004, 173, 1202-1208
    • (2004) J. Immunol. , vol.173 , pp. 1202-1208
    • Wilson, H.L.1    Francis, S.E.2    Dower, S.K.3    Crossman, D.C.4
  • 97
    • 34247353273 scopus 로고    scopus 로고
    • Stimulation of P2 receptors causes release of IL-1beta-loaded microvesicles from human dendritic cells
    • Pizzirani, C.; Ferrari, D.; Chiozzi, P.; Adinolfi, E.; Sandona, D.; Savaglio, E.; Di Virgilio, F. Stimulation of P2 receptors causes release of IL-1beta-loaded microvesicles from human dendritic cells. Blood, 2007, 109, 3856-3864
    • (2007) Blood , vol.109 , pp. 3856-3864
    • Pizzirani, C.1    Ferrari, D.2    Chiozzi, P.3    Adinolfi, E.4    Sandona, D.5    Savaglio, E.6    Di Virgilio, F.7
  • 99
    • 84871348057 scopus 로고    scopus 로고
    • IL-18 associates to microvesicles shed from human macrophages by a LPS/TLR-4 independent mechanism in response to P2X receptor stimulation
    • Gulinelli, S.; Salaro, E.; Vuerich, M.; Bozzato, D.; Pizzirani, C.; Bolognesi, G.; Idzko, M.; Di Virgilio, F.; Ferrari, D. IL-18 associates to microvesicles shed from human macrophages by a LPS/TLR-4 independent mechanism in response to P2X receptor stimulation. Eur. J. Immunol., 2012, 42, 3334-3345
    • (2012) Eur. J. Immunol. , vol.42 , pp. 3334-3345
    • Gulinelli, S.1    Salaro, E.2    Vuerich, M.3    Bozzato, D.4    Pizzirani, C.5    Bolognesi, G.6    Idzko, M.7    Di Virgilio, F.8    Ferrari, D.9
  • 102
    • 1642483466 scopus 로고    scopus 로고
    • Early prostate cancer detected using expression of non-functional cytolytic P2X7 receptors
    • Slater, M.; Danieletto, S.; Gidley-Baird, A.; The, L.C.; Barden, J.A. Early prostate cancer detected using expression of non-functional cytolytic P2X7 receptors. Histopathology, 2004, 44, 206-215
    • (2004) Histopathology , vol.44 , pp. 206-215
    • Slater, M.1    Danieletto, S.2    Gidley-Baird, A.3    The, L.C.4    Barden, J.A.5
  • 103
    • 0028136987 scopus 로고
    • Apoptosis; But not necrosis; Of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guerin
    • Molloy, A.; Laochumroonvorapong, P.; Kaplan, G. Apoptosis; but not necrosis; of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guerin. J. Exp. Med., 1994, 180, 1499-1509
    • (1994) J. Exp. Med. , vol.180 , pp. 1499-1509
    • Molloy, A.1    Laochumroonvorapong, P.2    Kaplan, G.3
  • 104
    • 0030840444 scopus 로고    scopus 로고
    • ATP-induced killing of mycobacteria by human macrophages is mediated by purinergic P2Z(P2X7) receptors
    • Lammas, D.A.; Stober, C.; Harvey, C.J.; Kendrick, N.; Panchalingam, S.; Kumararatne, D.S. ATP-induced killing of mycobacteria by human macrophages is mediated by purinergic P2Z(P2X7) receptors. Immunity, 1997, 7, 433-444
    • (1997) Immunity , vol.7 , pp. 433-444
    • Lammas, D.A.1    Stober, C.2    Harvey, C.J.3    Kendrick, N.4    Panchalingam, S.5    Kumararatne, D.S.6
  • 105
    • 0033957426 scopus 로고    scopus 로고
    • ATP-induced killing of virulent Mycobacterium tuberculosis within human macrophages requires phospholipase
    • Kusner, D.J.; Adams, J. ATP-induced killing of virulent Mycobacterium tuberculosis within human macrophages requires phospholipase D. J. Immunol., 2000, 164, 379-388
    • (2000) D. J. Immunol. , vol.164 , pp. 379-388
    • Kusner, D.J.1    Adams, J.2
  • 106
    • 0242662713 scopus 로고    scopus 로고
    • A loss-of-function polymorphism in the human P2X7 receptor abolishes ATP-mediated killing of mycobacteria
    • Saunders, B.M.; Fernando, S.L.; Sluyter, R.; Britton, W.J.; Wiley, J.S. A loss-of-function polymorphism in the human P2X7 receptor abolishes ATP-mediated killing of mycobacteria. J. Immunol., 2003, 171, 5442-5446
    • (2003) J. Immunol. , vol.171 , pp. 5442-5446
    • Saunders, B.M.1    Fernando, S.L.2    Sluyter, R.3    Britton, W.J.4    Wiley, J.S.5
  • 107
    • 34247641287 scopus 로고    scopus 로고
    • P2X(7) purinergic receptors and extracellular ATP mediate apoptosis of human monocytes/ macrophages infected with Mycobacterium tuberculosis reducing the intracellular bacterial viability
    • Placido, R.; Auricchio, G.; Falzoni, S.; Battistini, L.; Colizzi, V.; Brunetti, E.; Di Virgilio, F.; Mancino, G. P2X(7) purinergic receptors and extracellular ATP mediate apoptosis of human monocytes/ macrophages infected with Mycobacterium tuberculosis reducing the intracellular bacterial viability. Cell. Immunol., 2006, 244, 10-18
    • (2006) Cell. Immunol. , vol.244 , pp. 10-18
    • Placido, R.1    Auricchio, G.2    Falzoni, S.3    Battistini, L.4    Colizzi, V.5    Brunetti, E.6    Di Virgilio, F.7    Mancino, G.8
  • 110
    • 84897506540 scopus 로고    scopus 로고
    • The effect of P2X7 receptor 1513 polymorphism on susceptibility to tuberculosis, a meta-analysis
    • Wu, G.; Zhao, M.; Gu, X.; Yao, Y.; Liu, H.; Song, Y. The effect of P2X7 receptor 1513 polymorphism on susceptibility to tuberculosis, a meta-analysis. Infect. Genet. Evol., 2014, 24, 82-91
    • (2014) Infect. Genet. Evol. , vol.24 , pp. 82-91
    • Wu, G.1    Zhao, M.2    Gu, X.3    Yao, Y.4    Liu, H.5    Song, Y.6
  • 111
    • 17644379097 scopus 로고    scopus 로고
    • The purinergic P2X7 receptor is not required for control of pulmonary Mycobacterium tuberculosis infection
    • Myers, A.J.; Eilertson, B.; Fulton, S.A.; Flynn, J.L.; Canaday, D.H. The purinergic P2X7 receptor is not required for control of pulmonary Mycobacterium tuberculosis infection. Infect. Immun., 2005, 73, 3192-3195
    • (2005) Infect. Immun. , vol.73 , pp. 3192-3195
    • Myers, A.J.1    Eilertson, B.2    Fulton, S.A.3    Flynn, J.L.4    Canaday, D.H.5
  • 115
    • 0028985997 scopus 로고
    • The purinergic P2Z receptor of human macrophage cells. Characterization and possible physiological role
    • Falzoni, S.; Munerati, M.; Ferrari, D.; Spisani, S.; Moretti, S.; Di Virgilio, F. The purinergic P2Z receptor of human macrophage cells. Characterization and possible physiological role. J. Clin. Invest., 1995, 95, 1207-1216
    • (1995) J. Clin. Invest. , vol.95 , pp. 1207-1216
    • Falzoni, S.1    Munerati, M.2    Ferrari, D.3    Spisani, S.4    Moretti, S.5    Di Virgilio, F.6
  • 118
    • 79954583662 scopus 로고    scopus 로고
    • The P2X7 receptor drives osteoclast fusion by increasing the extracellular adenosine concentration
    • Pellegatti, P.; Falzoni, S.; Donvito, G.; Lemaire, I.; Di Virgilio, F. The P2X7 receptor drives osteoclast fusion by increasing the extracellular adenosine concentration. FASEB J., 201, 25, 1264-1274
    • FASEB J. , vol.201 , Issue.25 , pp. 1264-1274
    • Pellegatti, P.1    Falzoni, S.2    Donvito, G.3    Lemaire, I.4    Di Virgilio, F.5
  • 123
    • 0018714680 scopus 로고
    • Increased ATP and creatine phosphate turnover in phagocytosing mouse peritoneal macrophages
    • Loike, J.D.; Kozler, V.F.; Silverstein, S.C. Increased ATP and creatine phosphate turnover in phagocytosing mouse peritoneal macrophages. J. Biol. Chem., 1979, 254, 9558-9564
    • (1979) J. Biol. Chem. , vol.254 , pp. 9558-9564
    • Loike, J.D.1    Kozler, V.F.2    Silverstein, S.C.3
  • 125
    • 77949902247 scopus 로고    scopus 로고
    • The P2X7-nonmuscle myosin membrane complex regulates phagocytosis of nonopsonized particles and bacteria by a pathway attenuated by extracellular ATP
    • Gu, B.J.; Saunders, B.M.; Jursik, C.; Wiley, J.S. The P2X7-nonmuscle myosin membrane complex regulates phagocytosis of nonopsonized particles and bacteria by a pathway attenuated by extracellular ATP. Blood, 2010, 115, 1621-1631
    • (2010) Blood , vol.115 , pp. 1621-1631
    • Gu, B.J.1    Saunders, B.M.2    Jursik, C.3    Wiley, J.S.4
  • 126
    • 80052682243 scopus 로고    scopus 로고
    • P2X(7) is a scavenger receptor for apoptotic cells in the absence of its ligand; Extracellular ATP
    • Gu, B.J.; Saunders, B.M.; Petrou, S.; Wiley, J.S. P2X(7) is a scavenger receptor for apoptotic cells in the absence of its ligand; extracellular ATP. J. Immunol., 2011, 187, 2365-2375
    • (2011) J. Immunol. , vol.187 , pp. 2365-2375
    • Gu, B.J.1    Saunders, B.M.2    Petrou, S.3    Wiley, J.S.4
  • 131
    • 84899474157 scopus 로고    scopus 로고
    • Technical Advance, a new cell preparation strategy that greatly improves the yield of vital and functional Tregs and NKT cells
    • Rissiek, B.; Danquah, W.; Haag, F.; Koch-Nolte, F. Technical Advance, a new cell preparation strategy that greatly improves the yield of vital and functional Tregs and NKT cells. J. Leukoc. Biol., 2014, 95, 543-549
    • (2014) J. Leukoc. Biol. , vol.95 , pp. 543-549
    • Rissiek, B.1    Danquah, W.2    Haag, F.3    Koch-Nolte, F.4
  • 139
    • 1642504343 scopus 로고    scopus 로고
    • ATP-and adenosine-mediated signaling in the central nervous system, chronic pain and microglia, involvement of the ATP receptor P2X4
    • Inoue, K.; Tsuda, M.; Koizumi, S. ATP-and adenosine-mediated signaling in the central nervous system, chronic pain and microglia, involvement of the ATP receptor P2X4. J. Pharmacol. Sci., 2004, 94, 112-114
    • (2004) J. Pharmacol. Sci. , vol.94 , pp. 112-114
    • Inoue, K.1    Tsuda, M.2    Koizumi, S.3
  • 140
    • 84861528073 scopus 로고    scopus 로고
    • P2X4 purinoceptor signaling in chronic pain
    • Trang, T.; Salter, M.W. P2X4 purinoceptor signaling in chronic pain. Purinergic. Signal., 2012, 8, 621-628
    • (2012) Purinergic. Signal. , vol.8 , pp. 621-628
    • Trang, T.1    Salter, M.W.2
  • 142
    • 0037135302 scopus 로고    scopus 로고
    • Antinociceptive effect of a new P(2Z)/P2X7 antagonist; Oxidized ATP; In arthritic rats
    • Dell'Antonio, G.; Quattrini, A.; Dal, C.E.; Fulgenzi, A.; Ferrero, M.E. Antinociceptive effect of a new P(2Z)/P2X7 antagonist; oxidized ATP; in arthritic rats. Neurosci. Lett., 2002, 327, 87-90
    • (2002) Neurosci. Lett. , vol.327 , pp. 87-90
    • Dell'Antonio, G.1    Quattrini, A.2    Dal, C.E.3    Fulgenzi, A.4    Ferrero, M.E.5
  • 143
    • 0036899591 scopus 로고    scopus 로고
    • Relief of inflammatory pain in rats by local use of the selective P2X7 ATP receptor inhibitor; Oxidized ATP
    • Dell'Antonio, G.; Quattrini, A.; Cin, E.D.; Fulgenzi, A.; Ferrero, M.E. Relief of inflammatory pain in rats by local use of the selective P2X7 ATP receptor inhibitor; oxidized ATP. Arthritis Rheum., 2002, 46, 3378-3385
    • (2002) Arthritis Rheum. , vol.46 , pp. 3378-3385
    • Dell'Antonio, G.1    Quattrini, A.2    Cin, E.D.3    Fulgenzi, A.4    Ferrero, M.E.5
  • 145
    • 79960459555 scopus 로고    scopus 로고
    • Mechanistic differentiation of cancer pain, a pivotal role of P2X7 is absent
    • Chessell, I.; Hatcher, J.; Billinton, A. Mechanistic differentiation of cancer pain, a pivotal role of P2X7 is absent. Pain, 2011, 152, 1703-1704
    • (2011) Pain , vol.152 , pp. 1703-1704
    • Chessell, I.1    Hatcher, J.2    Billinton, A.3
  • 147
    • 84892519201 scopus 로고    scopus 로고
    • Purinergic mechanisms and pain-an update
    • Burnstock, G. Purinergic mechanisms and pain-an update. Eur. J. Pharmacol., 2013, 716, 24-40
    • (2013) Eur. J. Pharmacol. , vol.716 , pp. 24-40
    • Burnstock, G.1
  • 148
    • 0036671894 scopus 로고    scopus 로고
    • The inflammasome, a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
    • Martinon, F.; Burns, K.; Tschopp, J. The inflammasome, a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol. Cell., 2002, 10, 417-426
    • (2002) Mol. Cell. , vol.10 , pp. 417-426
    • Martinon, F.1    Burns, K.2    Tschopp, J.3
  • 149
    • 0031451872 scopus 로고    scopus 로고
    • A primary role for K+ and Na+ efflux in the activation of apoptosis
    • Bortner, C.D.; Hughes, F.M.; Jr.; Cidlowski, J.A. A primary role for K+ and Na+ efflux in the activation of apoptosis. J. Biol. Chem., 1997, 272, 32436-32442
    • (1997) J. Biol. Chem. , vol.272 , pp. 32436-32442
    • Bortner, C.D.1    Hughes, Jr.F.M.2    Cidlowski, J.A.3
  • 151
    • 0024988964 scopus 로고
    • Responses of mouse lymphocytes to extracellular ATP. II. Extracellular ATP causes cell type-dependent lysis and DNA fragmentation
    • Zanovello, P.; Bronte, V.; Rosato, A.; Pizzo, P.; Di Virgilio, F. Responses of mouse lymphocytes to extracellular ATP. II. Extracellular ATP causes cell type-dependent lysis and DNA fragmentation. J. Immunol., 1990, 145, 1545-1550
    • (1990) J. Immunol. , vol.145 , pp. 1545-1550
    • Zanovello, P.1    Bronte, V.2    Rosato, A.3    Pizzo, P.4    Di Virgilio, F.5
  • 152
    • 14444281120 scopus 로고    scopus 로고
    • Activation by P2X7 agonists of two phospholipases A2 (PLA2) in ductal cells of rat submandibular gland. Coupling of the calciumindependent PLA2 with kallikrein secretion
    • Alzola, E.; Perez-Etxebarria, A.; Kabre, E.; Fogarty, D.J.; Metioui, M.; Chaib, N.; Macarulla, J.M.; Matute, C.; Dehaye, J.P.; Marino, A. Activation by P2X7 agonists of two phospholipases A2 (PLA2) in ductal cells of rat submandibular gland. Coupling of the calciumindependent PLA2 with kallikrein secretion. J. Biol. Chem., 1998, 273, 30208-30217
    • (1998) J. Biol. Chem. , vol.273 , pp. 30208-30217
    • Alzola, E.1    Perez-Etxebarria, A.2    Kabre, E.3    Fogarty, D.J.4    Metioui, M.5    Chaib, N.6    Macarulla, J.M.7    Matute, C.8    Dehaye, J.P.9    Marino, A.10
  • 154
    • 0033556708 scopus 로고    scopus 로고
    • Activation of the P2Z/P2X7 receptor in human lymphocytes produces a delayed permeability lesion, involvement of phospholipase D
    • Fernando, K.C.; Gargett, C.E.; Wiley, J.S. Activation of the P2Z/P2X7 receptor in human lymphocytes produces a delayed permeability lesion, involvement of phospholipase D. Arch. Biochem. Biophys., 1999, 362, 197-202
    • (1999) Arch. Biochem. Biophys. , vol.362 , pp. 197-202
    • Fernando, K.C.1    Gargett, C.E.2    Wiley, J.S.3
  • 155
    • 0035881559 scopus 로고    scopus 로고
    • Cutting edge, the nucleotide receptor P2X7 contains multiple protein-and lipid-interaction motifs including a potential binding site for bacterial lipopolysaccharide
    • Denlinger, L.C.; Fisette, P.L.; Sommer, J.A.; Watters, J.J.; Prabhu, U.; Dubyak, G.R.; Proctor, R.A.; Bertics, P.J. Cutting edge, the nucleotide receptor P2X7 contains multiple protein-and lipid-interaction motifs including a potential binding site for bacterial lipopolysaccharide. J. Immunol., 2001, 167, 1871-1876
    • (2001) J. Immunol. , vol.167 , pp. 1871-1876
    • Denlinger, L.C.1    Fisette, P.L.2    Sommer, J.A.3    Watters, J.J.4    Prabhu, U.5    Dubyak, G.R.6    Proctor, R.A.7    Bertics, P.J.8
  • 156
    • 0141621228 scopus 로고    scopus 로고
    • Tyrosine Phosphorylation of HSP90 within the P2X7 Receptor Complex Negatively Regulates P2X7 Receptors
    • Adinolfi, E.; Kim, M.; Young, M.T.; Di Virgilio, F.; Surprenant, A. Tyrosine Phosphorylation of HSP90 within the P2X7 Receptor Complex Negatively Regulates P2X7 Receptors. J. Biol. Chem., 2003, 278, 37344-37351
    • (2003) J. Biol. Chem. , vol.278 , pp. 37344-37351
    • Adinolfi, E.1    Kim, M.2    Young, M.T.3    Di Virgilio, F.4    Surprenant, A.5
  • 157
    • 33750473352 scopus 로고    scopus 로고
    • Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor
    • Pelegrin, P.; Surprenant, A. Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J., 2006, 25, 5071-5082
    • (2006) EMBO J. , vol.25 , pp. 5071-5082
    • Pelegrin, P.1    Surprenant, A.2
  • 158
    • 59449086148 scopus 로고    scopus 로고
    • The P2X7 receptor channel pore dilates under physiological ion conditions
    • Yan, Z.; Li, S.; Liang, Z.; Tomic, M.;Stojilkovic, S.S. The P2X7 receptor channel pore dilates under physiological ion conditions. J. Gen. Physiol., 2008, 132, 563-573
    • (2008) J. Gen. Physiol. , vol.132 , pp. 563-573
    • Yan, Z.1    Li, S.2    Liang, Z.3    Tomic, M.4    Stojilkovic, S.S.5
  • 160
    • 36549041874 scopus 로고    scopus 로고
    • Regulation of P2X4 receptors by lysosomal targeting; Glycan protection and exocytosis
    • Qureshi, O.S.; Paramasivam, A.; Yu, J.C.; Murrell-Lagnado, R.D. Regulation of P2X4 receptors by lysosomal targeting; glycan protection and exocytosis. J. Cell Sci., 2007, 120, 3838-3849
    • (2007) J. Cell Sci. , vol.120 , pp. 3838-3849
    • Qureshi, O.S.1    Paramasivam, A.2    Yu, J.C.3    Murrell-Lagnado, R.D.4
  • 162
    • 84864680511 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor from microglia, a molecular substrate for neuropathic pain
    • Trang, T.; Beggs, S.; Salter, M.W. Brain-derived neurotrophic factor from microglia, a molecular substrate for neuropathic pain. Neuron Glia Biol., 2011, 7, 99-108.
    • (2011) Neuron Glia Biol. , vol.7 , pp. 99-108
    • Trang, T.1    Beggs, S.2    Salter, M.W.3


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