P2X4 receptors mediate PGE2 release by tissue-resident macrophages and initiate inflammatory pain

EMBO Journal

Volumn 29, Issue 14, 2010, Pages 2290-2300

  Ulmann, Lauriane ^a,b   Hirbec, Hélène ^a,b   Rassendren, François ^a,b  

^a INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

^b UNIV MONTPELLIER   (France)

Author keywords

Inflammation; macrophages; P2X4R purinergic receptors; pain; PGE2

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CYTOSOLIC PHOSPHOLIPASE A2; MITOGEN ACTIVATED PROTEIN KINASE P38; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; PURINERGIC P2X4 RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXPERIMENTAL MOUSE; EXUDATE; FOOT; HYPERALGESIA; INFLAMMATION; MOUSE; NONHUMAN; PAIN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; WILD TYPE;

ANIMALIA; MUS;

EID: 77954886436     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2010.126     Document Type: Article

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