ATP-induced killing of mycobacteria by human macrophages is mediated by purinergic P2Z(P2X7) receptors

Immunity

Volumn 7, Issue 3, 1997, Pages 433-444

  Lammas, D A ^a   Stober, C ^a   Harvey, C J ^a   Kendrick, N ^a   Panchalingam, S ^a   Kumararatne, D S ^a,b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b CITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BCG VACCINE; PURINE P2 RECEPTOR;

ANTIGEN RECOGNITION; APOPTOSIS; ARTICLE; BACTERICIDAL ACTIVITY; GENETIC HETEROGENEITY; HOST RESISTANCE; HUMAN; HUMAN CELL; INFECTION RESISTANCE; MACROPHAGE FUNCTION; MYCOBACTERIUM; PRIORITY JOURNAL;

EID: 0030840444     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80364-7     Document Type: Article

References (46)

1. Adams, D.O., and Hamilton, T.A. (1984). The cell biology of macrophage activation. Ann. rev. Immunol. 2, 283-318.
2. Barnes, P.F. and Molin, R.L. (1996). Human cellular immune responses to Mycobacterium tuberculosis. In Tuberculosis: Current Topics in Microbiology and Immunology. Shinnick, T. M., ed. (Berlin: Springer-Verlag), pp. 197-220.
3. Blanchard, D.K., McMillen, S., and Djeu, J.Y. (1991). IFN-γ enhances sensitivity of human macrophages to extracellular ATP-mediated lysis. J. Immunol. 147, 2579-2585.
4. Blanchard, D.K., Wei, S.W., Duan, C., Pericle, F., Diaz, J.I., and Djeu J.Y. (1995). Role of extracellular adenosine triphosphate in the cytolytic T-lymphocyte-mediated lysis of antigen presenting cells. Blood 85, 3173-3182.
5. Bronte, V., et al. (1996). Protein tyrosine kinases and phosphatases control apoptosis induced by extracellular adenosine 5́-triphosphate. Biochem. Biophys. Res. Commun. 218, 314-351.
6. Buell, G. et al. (1997). Gene structure and chromosomal localisation of the human P2X7 receptor. Receptors and Channels, in press.
7. Dannenberg, A.M. and Rook, G.A.W. (1994). Pathogenesis of pulmonary tuberculosis: an interplay of tissue damaging and macrophage-activating immune responses - dual mechanisms that control bacillary multiplication. In Tuberculosis: Pathogenesis, Protection and Control. Bloom, B., ed. (ASM, Washington, DC; ASM Press), pp. 459-481.
8. De Maria, R., et al. (1994). Triggering of human monocyte activation through CD69, a member of the natural killer gene complex family of signal transducting receptors. J. Exp. Med. 180, 1999-2004.
9. Di Virgilio, F., Pizzo, P., Zanovello, P., Bronte, V., and Collavo, D. (1990). Extracellular ATP as a possible mediator of cell-mediated cytotoxity. Immunol. Today 11, 274-277.
10. Di Virgilio, F. (1995). The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death. Immunol. Today 16, 524-528.
11. Dubyak, G.R., and El-Moatassim, C. (1993). Signal transduction via P2Z-purinergic receptors for extracellular ATP and other nucleotides. Am. J. Physiol. 265, C577-C606.
12. El-Moatassim, C., and Dubyak, G. (1993). Dissociation of the poreforming and phospholipase D activities stimulated via P2Z purinergic receptors in BAC1.2F5 macrophages. J. Biol. Chem. 268, 15571-15578.
13. Falazoni, S., Munerati, M., Ferrari, D., Spisani, S., Moretti, S., and Di Virgilio, F. (1995). The purinergic P2Z receptor of human macrophage cells. J. Clin. Invest. 95, 1207-1216.
14. + T cells fails to affect survival of intracellular Mycobacterium bovisbacille Calmette-Guerin (BCG). Clin. Exp. Immunol. 99, 82-89.
15. Ferrari, D., Chiozzi, P., Hanau, S., and Di Virgilio, F. (1997). Purinergic modulation of interlukin-1B release from microglial cells stimulated with bacterial endotoxin. J. Exp. Med. 185, 579-582.
16. Filippini, A., Taffs, R.E., Agui, T., and Sitkowsky, M.V. (1990). EctoATPase activity in cytolytic T-lymphocytes. Protection from the cytolytic effects of extracellular ATP. J. Biol. Chem. 265, 334-340.
17. Fredholm, B.B., Abbracchio, M.P., Burnstock, G., Daly, J.W., Harden, T. K., Jacobson, K.A., Leff, P., and Williams, M. (1994). Nomenclature and classification of purinoreceptors. Pharmocol. Rev. 46, 143-156.
18. Gargett, C.E., and Wiley, J.S. (1997). The isoquinoline derivative KN-62, a potent antagonist of the P2Z-receptor of human lymphocytes. Br. J. Parmacol. 120, 1483-1490.
19. Gonzalez, F.A., Wong, D.J., Huang, N.W., and Heppel, L.A. (1990). Activation of early events of the mitogenic response by a P2Y purinreceptor. Proc. Natl. Acad. Sci. USA. 67, 9717-9721.
20. Gordon, J.L. (1986). Extracellular ATP: effects, sources and fate. Biochem J. 233, 309-319.
21. Gorman, A., McCarthy, J., Finucane, D., Reville, W., and Cotter, T.G. (1996). Morphological assessment of apoptosis. In Apoptosis. S.J. Martin and T.G. Cotter, eds. (London: Portland Press Ltd.), pp. 1-2.
22. Humphreys, B.D., and Dubyak, G.R. (1996). Induction of the P2Z/ P2X7 nucleotide receptor and associated phospholipase D activity by lipopolysaccharide and IFN-γ in the human THP-1 monocytic cell line. J. Immunol. 157, 5627-5637.
23. Kaufmann, S.H.E. (1993). Immunity to intracellular bacteria. Annu. Rev. Immunol. 11, 129-163.
24. Laochumroonvorapong, P., Paul, S., Elkon, K.B., and Kaplan, G. (1996). H202 induces monocyte apoptosis and reduces viability of Mycobacterium avium-M. intracellulare within cultured human monocytes. Infect. Immun. 64, 452-459.
25. Laochumroonvorapong, P., Wang, J., Liu, C., Ye, W., Moreira, A.L., Elkon, K.B., Freedman, V.H., and Kaplan, G. (1997). Perform, a cytotoxic molecule which mediates cell necrosis is not required for the early control of mycobacterial infection in mice. Infect. Immun. 65, 127-132.
26. Malin, A.S. and McAdam, K.P.W.J. (1995). Escalating threat from tuberculosis: the third epidemic. Thorax. (Suppl. 1), 537-542.
27. Molloy, A., Laochumroonvorapong, P., and Kaplan, G. (1994). Apoptosis, but not necrosis of infected monocytes is coupled with killing of intracellular BCG. J. Exp. Med. 180, 1499-1509.
28. Murgia, M., Hanau, S., Pizzo, P., Rippa, M., and Di Virgilio, F. (1993). Oxidized ATP. An irreversible inhibitor of the macrophage purinergic receptor. J. Biol. Chem. 268, 8199-8203.
29. + RNAfrom murine macrophages. Mol. Pharmacol. 44, 93-101.
30. O'Brien, L., Roberts, B., and Andrews, P.W. (1996). In vitro interactions of Mycobacterium tuberculosis and macrophages. In Tuberculosis: Current Topics in Microbiology and Immunology. Shinnick, T.M., ed. (Berlin: Springer-Verlag), pp. 97-130.
31. Orme, I.M. (1996). Immune response in animal models. In Tuberculosis: Current Topics in Microbiology and Immunology. Shinnick, T.M., ed. (Berlin: Springer-Verlag), pp. 181-196.
32. Rassendren, F., Buell, G.N., Virgilinio, C., and Colloe, G. (1997). The permeabilizing ATP receptor, P2X7. Cloning and expression of a human cDNA. J. Biol. Chem. 272, 5482-5486.
33. Reif, D.W., and McCreedy, S.A. (1995). N-nitro-L-arginine and N-monomethyl-L-arginine exhibit a different pattern of inactivation towards the 3 nitric-oxide synthases. Arch. Biochem. Biophys. 320, 170-176.
34. Richardson, B.C., Lalwani, N., Johnson, K.J., and Marks, R.M. (1994). Fas ligation triggers apoptosis in macrophages but not endothelial cells. Eur. J. Immunol. 24, 2640-2645.
35. Segal, A.W. (1974). Nitroblue-tetrazolium tests. Lancet ii, 1248-1250.
36. Smith, R.M., and Curnutte, J.T. (1991). Molecular basis of chronic granulomatous disease. Blood 77, 673-686.
37. Snider, D.E. and La Montagne, J.R. (1994). The neglected global tuberculosis problem: a report of the 1992 World Congress of Tuberculosis. J. Infect. Dis. 169, 1189-1196.
38. Stead, W.W. (1992). Genetics and resistance to tuberculosis: could resistance be enhanced by genetic engineering? Ann. Intern. Med. 116, 937-941.
39. Steinberg, T.H., Swanson, J.A., and Silverstein, S.C. (1988). A prelysosomal compartment sequesters membrane-impermeant fluorescent dyes from the cytoplasmic matrix of J774 macrophages. J. Cell Biol. 107, 887-896.
40. Stenger, S., Mazzaccaro, R.J., Uyemura, K., Cho, S., Barnes, P.F., Rosat, J., Sette, A., Brenner, M.B., Porcelli, S.A., Bloom, B.R., and Modlin, R.L. (1997). Differential effects of cytolytic T cell subsets on intracellular infection. Science 276, 1684-1687.
41. P2X7). Science 272, 735-737.
42. 2+ dependent protein kinase. Biochem. Biophys. Res. Commun. 135, 397-402.
43. Tascon, R.E., Colston, M.J., Ragno, S., Stavropoulos, E., Gregory, D., and Lowrie, D.B. (1996). Vaccination against tuberculosis by DNA injection. Nature Medicine 2, 888-892.
44. Thastrup, O., Dawson, A.P., Schaff, O., Foder, B., Cullen, R.J., Drobak, B.K., Bjerrum, P.J., Christensen, S.B., and Hanley, M.R. (1989). Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage. Agents Actions 27, 17-23.
45. 4- receptor-operated ion channel of human lymphocytes: inhibition of ion-fluxes by amiloride analogs and by extracellular sodium ions. Arch. Biochem. Biophys. 292, 411-418.
46. + uptake: inhibition of fluxes by suramin. Arch. Biochem. Biophys. 305, 54-60.