-
1
-
-
20044370505
-
High cholesterol level is essential for myelin membrane growth
-
G. Saher, B. Brugger, C. Lappe-Siefke, W. Mobius, R. Tozawa, M.C. Wehr, F. Wieland, S. Ishibashi, and K.A. Nave High cholesterol level is essential for myelin membrane growth Nat. Neurosci. 8 2005 468 475
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 468-475
-
-
Saher, G.1
Brugger, B.2
Lappe-Siefke, C.3
Mobius, W.4
Tozawa, R.5
Wehr, M.C.6
Wieland, F.7
Ishibashi, S.8
Nave, K.A.9
-
3
-
-
84872619419
-
Lipidome and proteome map of myelin membranes
-
G. Gopalakrishnan, A. Awasthi, W. Belkaid, O. De Faria Jr., D. Liazoghli, D.R. Colman, and A.S. Dhaunchak Lipidome and proteome map of myelin membranes J. Neurosci. Res. 91 2013 321 334
-
(2013)
J. Neurosci. Res.
, vol.91
, pp. 321-334
-
-
Gopalakrishnan, G.1
Awasthi, A.2
Belkaid, W.3
De Faria, O.4
Liazoghli, D.5
Colman, D.R.6
Dhaunchak, A.S.7
-
4
-
-
45949105768
-
Polarity development in oligodendrocytes: Sorting and trafficking of myelin components
-
O. Maier, D. Hoekstra, and W. Baron Polarity development in oligodendrocytes: sorting and trafficking of myelin components J. Mol. Neurosci. 35 2008 35 53
-
(2008)
J. Mol. Neurosci.
, vol.35
, pp. 35-53
-
-
Maier, O.1
Hoekstra, D.2
Baron, W.3
-
5
-
-
77954692663
-
Developmental profiling by mass spectrometry of phosphocholine containing phospholipids in the rat nervous system reveals temporo-spatial gradients
-
C. Lohmann, E. Schachmann, T. Dandekar, C. Villmann, and C.M. Becker Developmental profiling by mass spectrometry of phosphocholine containing phospholipids in the rat nervous system reveals temporo-spatial gradients J. Neurochem. 114 2010 1119 1134
-
(2010)
J. Neurochem.
, vol.114
, pp. 1119-1134
-
-
Lohmann, C.1
Schachmann, E.2
Dandekar, T.3
Villmann, C.4
Becker, C.M.5
-
6
-
-
0035834416
-
CNS synaptogenesis promoted by glia-derived cholesterol
-
D.H. Mauch, K. Nagler, S. Schumacher, C. Goritz, E.C. Muller, A. Otto, and F.W. Pfrieger CNS synaptogenesis promoted by glia-derived cholesterol Science 294 2001 1354 1357
-
(2001)
Science
, vol.294
, pp. 1354-1357
-
-
Mauch, D.H.1
Nagler, K.2
Schumacher, S.3
Goritz, C.4
Muller, E.C.5
Otto, A.6
Pfrieger, F.W.7
-
7
-
-
77955108799
-
Genetic connections between neurological disorders and cholesterol metabolism
-
I. Bjorkhem, V. Leoni, and S. Meaney Genetic connections between neurological disorders and cholesterol metabolism J. Lipid Res. 51 2010 2489 2503
-
(2010)
J. Lipid Res.
, vol.51
, pp. 2489-2503
-
-
Bjorkhem, I.1
Leoni, V.2
Meaney, S.3
-
8
-
-
0029844192
-
Cholesterol modification of hedgehog signaling proteins in animal development
-
J.A. Porter, K.E. Young, and P.A. Beachy Cholesterol modification of hedgehog signaling proteins in animal development Science 274 1996 255 259
-
(1996)
Science
, vol.274
, pp. 255-259
-
-
Porter, J.A.1
Young, K.E.2
Beachy, P.A.3
-
9
-
-
0036471671
-
Sonic hedgehog in the nervous system: Functions, modifications and mechanisms
-
K.S. Ho, and M.P. Scott Sonic hedgehog in the nervous system: functions, modifications and mechanisms Curr. Opin. Neurobiol. 12 2002 57 63
-
(2002)
Curr. Opin. Neurobiol.
, vol.12
, pp. 57-63
-
-
Ho, K.S.1
Scott, M.P.2
-
10
-
-
33748681724
-
Estrogen receptor protein interaction with phosphatidylinositol 3-kinase leads to activation of phosphorylated Akt and extracellular signal-regulated kinase 1/2 in the same population of cortical neurons: A unified mechanism of estrogen action
-
P. Mannella, and R.D. Brinton Estrogen receptor protein interaction with phosphatidylinositol 3-kinase leads to activation of phosphorylated Akt and extracellular signal-regulated kinase 1/2 in the same population of cortical neurons: a unified mechanism of estrogen action J. Neurosci. 26 2006 9439 9447
-
(2006)
J. Neurosci.
, vol.26
, pp. 9439-9447
-
-
Mannella, P.1
Brinton, R.D.2
-
11
-
-
0035653923
-
The estrogen trinity: Membrane, cytosolic, and nuclear effects
-
A. Nadal, M. Diaz, and M.A. Valverde The estrogen trinity: membrane, cytosolic, and nuclear effects News Physiol. Sci. 16 2001 251 255
-
(2001)
News Physiol. Sci.
, vol.16
, pp. 251-255
-
-
Nadal, A.1
Diaz, M.2
Valverde, M.A.3
-
13
-
-
40749124836
-
Neuroactive steroids and peripheral neuropathy
-
I. Roglio, S. Giatti, M. Pesaresi, R. Bianchi, G. Cavaletti, G. Lauria, L.M. Garcia-Segura, and R.C. Melcangi Neuroactive steroids and peripheral neuropathy Brain Res. Rev. 57 2008 460 469
-
(2008)
Brain Res. Rev.
, vol.57
, pp. 460-469
-
-
Roglio, I.1
Giatti, S.2
Pesaresi, M.3
Bianchi, R.4
Cavaletti, G.5
Lauria, G.6
Garcia-Segura, L.M.7
Melcangi, R.C.8
-
14
-
-
0033594903
-
CDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain
-
E.G. Lund, J.M. Guileyardo, and D.W. Russell cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain Proc. Natl. Acad. Sci. U. S. A. 96 1999 7238 7243
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 7238-7243
-
-
Lund, E.G.1
Guileyardo, J.M.2
Russell, D.W.3
-
15
-
-
33751096969
-
Crossing the barrier: Oxysterols as cholesterol transporters and metabolic modulators in the brain
-
I. Bjorkhem Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain J. Intern. Med. 260 2006 493 508
-
(2006)
J. Intern. Med.
, vol.260
, pp. 493-508
-
-
Bjorkhem, I.1
-
16
-
-
84872677234
-
Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis
-
S. Theofilopoulos, Y. Wang, S.S. Kitambi, P. Sacchetti, K.M. Sousa, K. Bodin, J. Kirk, C. Salto, M. Gustafsson, E.M. Toledo, K. Karu, J.A. Gustafsson, K.R. Steffensen, P. Ernfors, J. Sjovall, W.J. Griffiths, and E. Arenas Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis Nat. Chem. Biol. 9 2013 126 133
-
(2013)
Nat. Chem. Biol.
, vol.9
, pp. 126-133
-
-
Theofilopoulos, S.1
Wang, Y.2
Kitambi, S.S.3
Sacchetti, P.4
Sousa, K.M.5
Bodin, K.6
Kirk, J.7
Salto, C.8
Gustafsson, M.9
Toledo, E.M.10
Karu, K.11
Gustafsson, J.A.12
Steffensen, K.R.13
Ernfors, P.14
Sjovall, J.15
Griffiths, W.J.16
Arenas, E.17
-
17
-
-
79954986242
-
Oxysterol derivatives of cholesterol in neurodegenerative disorders
-
T.M. Jeitner, I. Voloshyna, and A.B. Reiss Oxysterol derivatives of cholesterol in neurodegenerative disorders Curr. Med. Chem. 18 2011 1515 1525
-
(2011)
Curr. Med. Chem.
, vol.18
, pp. 1515-1525
-
-
Jeitner, T.M.1
Voloshyna, I.2
Reiss, A.B.3
-
19
-
-
14444285707
-
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway
-
J.M. Lehmann, S.A. Kliewer, L.B. Moore, T.A. Smith-Oliver, B.B. Oliver, J.L. Su, S.S. Sundseth, D.A. Winegar, D.E. Blanchard, T.A. Spencer, and T.M. Willson Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway J. Biol. Chem. 272 1997 3137 3140
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3137-3140
-
-
Lehmann, J.M.1
Kliewer, S.A.2
Moore, L.B.3
Smith-Oliver, T.A.4
Oliver, B.B.5
Su, J.L.6
Sundseth, S.S.7
Winegar, D.A.8
Blanchard, D.E.9
Spencer, T.A.10
Willson, T.M.11
-
20
-
-
14844359386
-
Inactivation of liver X receptor beta leads to adult-onset motor neuron degeneration in male mice
-
S. Andersson, N. Gustafsson, M. Warner, and J.A. Gustafsson Inactivation of liver X receptor beta leads to adult-onset motor neuron degeneration in male mice Proc. Natl. Acad. Sci. U. S. A. 102 2005 3857 3862
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 3857-3862
-
-
Andersson, S.1
Gustafsson, N.2
Warner, M.3
Gustafsson, J.A.4
-
21
-
-
51649114789
-
Expression of liver X receptor beta is essential for formation of superficial cortical layers and migration of later-born neurons
-
X. Fan, H.J. Kim, D. Bouton, M. Warner, and J.A. Gustafsson Expression of liver X receptor beta is essential for formation of superficial cortical layers and migration of later-born neurons Proc. Natl. Acad. Sci. U. S. A. 105 2008 13445 13450
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 13445-13450
-
-
Fan, X.1
Kim, H.J.2
Bouton, D.3
Warner, M.4
Gustafsson, J.A.5
-
22
-
-
0037108819
-
Liver X receptors in the central nervous system: From lipid homeostasis to neuronal degeneration
-
L. Wang, G.U. Schuster, K. Hultenby, Q. Zhang, S. Andersson, and J.A. Gustafsson Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration Proc. Natl. Acad. Sci. U. S. A. 99 2002 13878 13883
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 13878-13883
-
-
Wang, L.1
Schuster, G.U.2
Hultenby, K.3
Zhang, Q.4
Andersson, S.5
Gustafsson, J.A.6
-
23
-
-
80052965098
-
Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo
-
M. Shafaati, M. Olin, A. Bavner, H. Pettersson, B. Rozell, S. Meaney, P. Parini, and I. Bjorkhem Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo J. Intern. Med. 270 2011 377 387
-
(2011)
J. Intern. Med.
, vol.270
, pp. 377-387
-
-
Shafaati, M.1
Olin, M.2
Bavner, A.3
Pettersson, H.4
Rozell, B.5
Meaney, S.6
Parini, P.7
Bjorkhem, I.8
-
25
-
-
84886690869
-
The major brain cholesterol metabolite 24(S)-hydroxycholesterol is a potent allosteric modulator of N-methyl-d-aspartate receptors
-
S.M. Paul, J.J. Doherty, A.J. Robichaud, G.M. Belfort, B.Y. Chow, R.S. Hammond, D.C. Crawford, A.J. Linsenbardt, H.J. Shu, Y. Izumi, S.J. Mennerick, and C.F. Zorumski The major brain cholesterol metabolite 24(S)-hydroxycholesterol is a potent allosteric modulator of N-methyl-d-aspartate receptors J. Neurosci. 33 2013 17290 17300
-
(2013)
J. Neurosci.
, vol.33
, pp. 17290-17300
-
-
Paul, S.M.1
Doherty, J.J.2
Robichaud, A.J.3
Belfort, G.M.4
Chow, B.Y.5
Hammond, R.S.6
Crawford, D.C.7
Linsenbardt, A.J.8
Shu, H.J.9
Izumi, Y.10
Mennerick, S.J.11
Zorumski, C.F.12
-
26
-
-
84885165023
-
Suppression of amyloid-beta production by 24S-hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking
-
Y. Urano, S. Ochiai, and N. Noguchi Suppression of amyloid-beta production by 24S-hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking FASEB J. 27 2013 4305 4315
-
(2013)
FASEB J.
, vol.27
, pp. 4305-4315
-
-
Urano, Y.1
Ochiai, S.2
Noguchi, N.3
-
27
-
-
74149083432
-
Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease
-
E. Hudry, D. Van Dam, W. Kulik, P.P. De Deyn, F.S. Stet, O. Ahouansou, A. Benraiss, A. Delacourte, P. Bougneres, P. Aubourg, and N. Cartier Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease Mol. Ther. 18 2010 44 53
-
(2010)
Mol. Ther.
, vol.18
, pp. 44-53
-
-
Hudry, E.1
Van Dam, D.2
Kulik, W.3
De Deyn, P.P.4
Stet, F.S.5
Ahouansou, O.6
Benraiss, A.7
Delacourte, A.8
Bougneres, P.9
Aubourg, P.10
Cartier, N.11
-
28
-
-
0035856407
-
On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells
-
N. Bogdanovic, L. Bretillon, E.G. Lund, U. Diczfalusy, L. Lannfelt, B. Winblad, D.W. Russell, and I. Bjorkhem On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells Neurosci. Lett. 314 2001 45 48
-
(2001)
Neurosci. Lett.
, vol.314
, pp. 45-48
-
-
Bogdanovic, N.1
Bretillon, L.2
Lund, E.G.3
Diczfalusy, U.4
Lannfelt, L.5
Winblad, B.6
Russell, D.W.7
Bjorkhem, I.8
-
29
-
-
77950949737
-
Increased expression of cholesterol 24S-hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: A potential role in Alzheimer's disease
-
G. Tian, Q. Kong, L. Lai, A. Ray-Chaudhury, and C.L. Lin Increased expression of cholesterol 24S-hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: a potential role in Alzheimer's disease J. Neurochem. 113 2010 978 989
-
(2010)
J. Neurochem.
, vol.113
, pp. 978-989
-
-
Tian, G.1
Kong, Q.2
Lai, L.3
Ray-Chaudhury, A.4
Lin, C.L.5
-
30
-
-
77951156488
-
Cerebrospinal fluid steroidomics: Are bioactive bile acids present in brain?
-
M. Ogundare, S. Theofilopoulos, A. Lockhart, L.J. Hall, E. Arenas, J. Sjovall, A.G. Brenton, Y. Wang, and W.J. Griffiths Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? J. Biol. Chem. 285 2010 4666 4679
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 4666-4679
-
-
Ogundare, M.1
Theofilopoulos, S.2
Lockhart, A.3
Hall, L.J.4
Arenas, E.5
Sjovall, J.6
Brenton, A.G.7
Wang, Y.8
Griffiths, W.J.9
-
31
-
-
78649386642
-
The bile acid receptor TGR5 (Gpbar-1) acts as a neurosteroid receptor in brain
-
V. Keitel, B. Gorg, H.J. Bidmon, I. Zemtsova, L. Spomer, K. Zilles, and D. Haussinger The bile acid receptor TGR5 (Gpbar-1) acts as a neurosteroid receptor in brain Glia 58 2010 1794 1805
-
(2010)
Glia
, vol.58
, pp. 1794-1805
-
-
Keitel, V.1
Gorg, B.2
Bidmon, H.J.3
Zemtsova, I.4
Spomer, L.5
Zilles, K.6
Haussinger, D.7
-
32
-
-
75849118078
-
SCAP is required for timely and proper myelin membrane synthesis
-
M.H. Verheijen, N. Camargo, V. Verdier, K. Nadra, A.S. de Preux Charles, J.J. Medard, A. Luoma, M. Crowther, H. Inouye, H. Shimano, S. Chen, J.F. Brouwers, J.B. Helms, M.L. Feltri, L. Wrabetz, D. Kirschner, R. Chrast, and A.B. Smit SCAP is required for timely and proper myelin membrane synthesis Proc. Natl. Acad. Sci. U. S. A. 106 2009 21383 21388
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 21383-21388
-
-
Verheijen, M.H.1
Camargo, N.2
Verdier, V.3
Nadra, K.4
De Preux Charles, A.S.5
Medard, J.J.6
Luoma, A.7
Crowther, M.8
Inouye, H.9
Shimano, H.10
Chen, S.11
Brouwers, J.F.12
Helms, J.B.13
Feltri, M.L.14
Wrabetz, L.15
Kirschner, D.16
Chrast, R.17
Smit, A.B.18
-
33
-
-
0141594942
-
Local regulation of fat metabolism in peripheral nerves
-
M.H. Verheijen, R. Chrast, P. Burrola, and G. Lemke Local regulation of fat metabolism in peripheral nerves Genes Dev. 17 2003 2450 2464
-
(2003)
Genes Dev.
, vol.17
, pp. 2450-2464
-
-
Verheijen, M.H.1
Chrast, R.2
Burrola, P.3
Lemke, G.4
-
34
-
-
80053611084
-
Fatty acid transport into the brain: Of fatty acid fables and lipid tails
-
R.W. Mitchell, and G.M. Hatch Fatty acid transport into the brain: of fatty acid fables and lipid tails Prostaglandins Leukot. Essent. Fat. Acids 85 2011 293 302
-
(2011)
Prostaglandins Leukot. Essent. Fat. Acids
, vol.85
, pp. 293-302
-
-
Mitchell, R.W.1
Hatch, G.M.2
-
35
-
-
84897024194
-
Transfer of omega-3 fatty acids across the blood-brain barrier after dietary supplementation with a docosahexaenoic acid-rich omega-3 fatty acid preparation in patients with Alzheimer's disease: The OmegAD study
-
Y. Freund Levi, I. Vedin, T. Cederholm, H. Basun, G. Faxen Irving, M. Eriksdotter, E. Hjorth, M. Schultzberg, B. Vessby, L.O. Wahlund, N. Salem Jr., and J. Palmblad Transfer of omega-3 fatty acids across the blood-brain barrier after dietary supplementation with a docosahexaenoic acid-rich omega-3 fatty acid preparation in patients with Alzheimer's disease: the OmegAD study J. Intern. Med. 275 2014 428 436
-
(2014)
J. Intern. Med.
, vol.275
, pp. 428-436
-
-
Freund Levi, Y.1
Vedin, I.2
Cederholm, T.3
Basun, H.4
Faxen Irving, G.5
Eriksdotter, M.6
Hjorth, E.7
Schultzberg, M.8
Vessby, B.9
Wahlund, L.O.10
Salem, N.11
Palmblad, J.12
-
36
-
-
84879784427
-
Metabolic signaling by lactate in the brain
-
L.F. Barros Metabolic signaling by lactate in the brain Trends Neurosci. 36 2013 396 404
-
(2013)
Trends Neurosci.
, vol.36
, pp. 396-404
-
-
Barros, L.F.1
-
37
-
-
84885023188
-
Why does brain metabolism not favor burning of fatty acids to provide energy? Reflections on disadvantages of the use of free fatty acids as fuel for brain
-
P. Schonfeld, and G. Reiser Why does brain metabolism not favor burning of fatty acids to provide energy? Reflections on disadvantages of the use of free fatty acids as fuel for brain J. Cereb. Blood Flow Metab. 33 2013 1493 1499
-
(2013)
J. Cereb. Blood Flow Metab.
, vol.33
, pp. 1493-1499
-
-
Schonfeld, P.1
Reiser, G.2
-
38
-
-
80053109845
-
Central nervous system myelin: Structure, synthesis and assembly
-
S. Aggarwal, L. Yurlova, and M. Simons Central nervous system myelin: structure, synthesis and assembly Trends Cell Biol. 21 2011 585 593
-
(2011)
Trends Cell Biol.
, vol.21
, pp. 585-593
-
-
Aggarwal, S.1
Yurlova, L.2
Simons, M.3
-
39
-
-
77951929406
-
On the biogenesis of myelin membranes: Sorting, trafficking and cell polarity
-
W. Baron, and D. Hoekstra On the biogenesis of myelin membranes: sorting, trafficking and cell polarity FEBS Lett. 584 2010 1760 1770
-
(2010)
FEBS Lett.
, vol.584
, pp. 1760-1770
-
-
Baron, W.1
Hoekstra, D.2
-
40
-
-
0036169270
-
Prostaglandins as inflammatory messengers across the blood-brain barrier
-
D. Engblom, M. Ek, S. Saha, A. Ericsson-Dahlstrand, P.J. Jakobsson, and A. Blomqvist Prostaglandins as inflammatory messengers across the blood-brain barrier J. Mol. Med. (Berl) 80 2002 5 15
-
(2002)
J. Mol. Med. (Berl)
, vol.80
, pp. 5-15
-
-
Engblom, D.1
Ek, M.2
Saha, S.3
Ericsson-Dahlstrand, A.4
Jakobsson, P.J.5
Blomqvist, A.6
-
41
-
-
38849198682
-
Antiinflammatory and neuroprotective actions of COX2 inhibitors in the injured brain
-
K.I. Strauss Antiinflammatory and neuroprotective actions of COX2 inhibitors in the injured brain Brain Behav. Immun. 22 2008 285 298
-
(2008)
Brain Behav. Immun.
, vol.22
, pp. 285-298
-
-
Strauss, K.I.1
-
42
-
-
84886948548
-
Alterations of brain eicosanoid synthetic pathway in multiple sclerosis and in animal models of demyelination: Role of cyclooxygenase-2
-
S. Palumbo, and F. Bosetti Alterations of brain eicosanoid synthetic pathway in multiple sclerosis and in animal models of demyelination: role of cyclooxygenase-2 Prostaglandins Leukot. Essent. Fat. Acids 89 2013 273 278
-
(2013)
Prostaglandins Leukot. Essent. Fat. Acids
, vol.89
, pp. 273-278
-
-
Palumbo, S.1
Bosetti, F.2
-
43
-
-
84864484031
-
Neural circuitry engaged by prostaglandins during the sickness syndrome
-
C.B. Saper, A.A. Romanovsky, and T.E. Scammell Neural circuitry engaged by prostaglandins during the sickness syndrome Nat. Neurosci. 15 2012 1088 1095
-
(2012)
Nat. Neurosci.
, vol.15
, pp. 1088-1095
-
-
Saper, C.B.1
Romanovsky, A.A.2
Scammell, T.E.3
-
44
-
-
84861311129
-
Targeting pain mediators induced by injured nerve-derived COX2 and PGE2 to treat neuropathic pain
-
W. Ma, B. St-Jacques, and P.C. Duarte Targeting pain mediators induced by injured nerve-derived COX2 and PGE2 to treat neuropathic pain Expert Opin. Ther. Targets 16 2012 527 540
-
(2012)
Expert Opin. Ther. Targets
, vol.16
, pp. 527-540
-
-
Ma, W.1
St-Jacques, B.2
Duarte, P.C.3
-
45
-
-
43749115768
-
Non-redundant functions of cyclooxygenases: Oxygenation of endocannabinoids
-
C.A. Rouzer, and L.J. Marnett Non-redundant functions of cyclooxygenases: oxygenation of endocannabinoids J. Biol. Chem. 283 2008 8065 8069
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 8065-8069
-
-
Rouzer, C.A.1
Marnett, L.J.2
-
46
-
-
84883466059
-
Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation
-
D.J. Hermanson, N.D. Hartley, J. Gamble-George, N. Brown, B.C. Shonesy, P.J. Kingsley, R.J. Colbran, J. Reese, L.J. Marnett, and S. Patel Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation Nat. Neurosci. 16 2013 1291 1298
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 1291-1298
-
-
Hermanson, D.J.1
Hartley, N.D.2
Gamble-George, J.3
Brown, N.4
Shonesy, B.C.5
Kingsley, P.J.6
Colbran, R.J.7
Reese, J.8
Marnett, L.J.9
Patel, S.10
-
47
-
-
78650515190
-
Preferential localization of prostamide/prostaglandin F synthase in myelin sheaths of the central nervous system
-
K. Yoshikawa, S. Takei, S. Hasegawa-Ishii, Y. Chiba, A. Furukawa, N. Kawamura, M. Hosokawa, D.F. Woodward, K. Watanabe, and A. Shimada Preferential localization of prostamide/prostaglandin F synthase in myelin sheaths of the central nervous system Brain Res. 1367 2011 22 32
-
(2011)
Brain Res.
, vol.1367
, pp. 22-32
-
-
Yoshikawa, K.1
Takei, S.2
Hasegawa-Ishii, S.3
Chiba, Y.4
Furukawa, A.5
Kawamura, N.6
Hosokawa, M.7
Woodward, D.F.8
Watanabe, K.9
Shimada, A.10
-
48
-
-
33846857139
-
Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection
-
N.G. Bazan Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection Curr. Opin. Clin. Nutr. Metab. Care 10 2007 136 141
-
(2007)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.10
, pp. 136-141
-
-
Bazan, N.G.1
-
49
-
-
82455192824
-
Emerging roles of resolvins in the resolution of inflammation and pain
-
R.R. Ji, Z.Z. Xu, G. Strichartz, and C.N. Serhan Emerging roles of resolvins in the resolution of inflammation and pain Trends Neurosci. 34 2011 599 609
-
(2011)
Trends Neurosci.
, vol.34
, pp. 599-609
-
-
Ji, R.R.1
Xu, Z.Z.2
Strichartz, G.3
Serhan, C.N.4
-
50
-
-
84874644958
-
Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells
-
J.J. Hulce, A.B. Cognetta, M.J. Niphakis, S.E. Tully, and B.F. Cravatt Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells Nat. Methods 10 2013 259 264
-
(2013)
Nat. Methods
, vol.10
, pp. 259-264
-
-
Hulce, J.J.1
Cognetta, A.B.2
Niphakis, M.J.3
Tully, S.E.4
Cravatt, B.F.5
-
51
-
-
0034829757
-
7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome
-
B.U. Fitzky, F.F. Moebius, H. Asaoka, H. Waage-Baudet, L. Xu, G. Xu, N. Maeda, K. Kluckman, S. Hiller, H. Yu, A.K. Batta, S. Shefer, T. Chen, G. Salen, K. Sulik, R.D. Simoni, G.C. Ness, H. Glossmann, S.B. Patel, and G.S. Tint 7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome J. Clin. Invest. 108 2001 905 915
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 905-915
-
-
Fitzky, B.U.1
Moebius, F.F.2
Asaoka, H.3
Waage-Baudet, H.4
Xu, L.5
Xu, G.6
Maeda, N.7
Kluckman, K.8
Hiller, S.9
Yu, H.10
Batta, A.K.11
Shefer, S.12
Chen, T.13
Salen, G.14
Sulik, K.15
Simoni, R.D.16
Ness, G.C.17
Glossmann, H.18
Patel, S.B.19
Tint, G.S.20
more..
-
52
-
-
0037637624
-
Fatty acid synthesis is essential in embryonic development: Fatty acid synthase null mutants and most of the heterozygotes die in utero
-
S.S. Chirala, H. Chang, M. Matzuk, L. Abu-Elheiga, J. Mao, K. Mahon, M. Finegold, and S.J. Wakil Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero Proc. Natl. Acad. Sci. U. S. A. 100 2003 6358 6363
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 6358-6363
-
-
Chirala, S.S.1
Chang, H.2
Matzuk, M.3
Abu-Elheiga, L.4
Mao, J.5
Mahon, K.6
Finegold, M.7
Wakil, S.J.8
-
53
-
-
0032748583
-
Embryonic lethality and defective neural tube closure in mice lacking squalene synthase
-
R. Tozawa, S. Ishibashi, J. Osuga, H. Yagyu, T. Oka, Z. Chen, K. Ohashi, S. Perrey, F. Shionoiri, N. Yahagi, K. Harada, T. Gotoda, Y. Yazaki, and N. Yamada Embryonic lethality and defective neural tube closure in mice lacking squalene synthase J. Biol. Chem. 274 1999 30843 30848
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30843-30848
-
-
Tozawa, R.1
Ishibashi, S.2
Osuga, J.3
Yagyu, H.4
Oka, T.5
Chen, Z.6
Ohashi, K.7
Perrey, S.8
Shionoiri, F.9
Yahagi, N.10
Harada, K.11
Gotoda, T.12
Yazaki, Y.13
Yamada, N.14
-
54
-
-
67449111096
-
Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation
-
M.V. Chakravarthy, Y. Zhu, L. Yin, T. Coleman, K.L. Pappan, C.A. Marshall, M.L. McDaniel, and C.F. Semenkovich Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation J. Lipid Res. 50 2009 630 640
-
(2009)
J. Lipid Res.
, vol.50
, pp. 630-640
-
-
Chakravarthy, M.V.1
Zhu, Y.2
Yin, L.3
Coleman, T.4
Pappan, K.L.5
Marshall, C.A.6
McDaniel, M.L.7
Semenkovich, C.F.8
-
55
-
-
34548860424
-
Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis
-
M.V. Chakravarthy, Y. Zhu, M. Lopez, L. Yin, D.F. Wozniak, T. Coleman, Z. Hu, M. Wolfgang, A. Vidal-Puig, M.D. Lane, and C.F. Semenkovich Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis J. Clin. Invest. 117 2007 2539 2552
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2539-2552
-
-
Chakravarthy, M.V.1
Zhu, Y.2
Lopez, M.3
Yin, L.4
Wozniak, D.F.5
Coleman, T.6
Hu, Z.7
Wolfgang, M.8
Vidal-Puig, A.9
Lane, M.D.10
Semenkovich, C.F.11
-
56
-
-
68149098866
-
Identification of a physiologically relevant endogenous ligand for PPARalpha in liver
-
M.V. Chakravarthy, I.J. Lodhi, L. Yin, R.R. Malapaka, H.E. Xu, J. Turk, and C.F. Semenkovich Identification of a physiologically relevant endogenous ligand for PPARalpha in liver Cell 138 2009 476 488
-
(2009)
Cell
, vol.138
, pp. 476-488
-
-
Chakravarthy, M.V.1
Lodhi, I.J.2
Yin, L.3
Malapaka, R.R.4
Xu, H.E.5
Turk, J.6
Semenkovich, C.F.7
-
57
-
-
0347623324
-
Generation of viable cholesterol-free mice
-
A. Wechsler, A. Brafman, M. Shafir, M. Heverin, H. Gottlieb, G. Damari, S. Gozlan-Kelner, I. Spivak, O. Moshkin, E. Fridman, Y. Becker, R. Skaliter, P. Einat, A. Faerman, I. Bjorkhem, and E. Feinstein Generation of viable cholesterol-free mice Science 302 2003 2087
-
(2003)
Science
, vol.302
, pp. 2087
-
-
Wechsler, A.1
Brafman, A.2
Shafir, M.3
Heverin, M.4
Gottlieb, H.5
Damari, G.6
Gozlan-Kelner, S.7
Spivak, I.8
Moshkin, O.9
Fridman, E.10
Becker, Y.11
Skaliter, R.12
Einat, P.13
Faerman, A.14
Bjorkhem, I.15
Feinstein, E.16
-
58
-
-
66049119910
-
Cholesterol regulates the endoplasmic reticulum exit of the major membrane protein P0 required for peripheral myelin compaction
-
G. Saher, S. Quintes, W. Mobius, M.C. Wehr, E.M. Kramer-Albers, B. Brugger, and K.A. Nave Cholesterol regulates the endoplasmic reticulum exit of the major membrane protein P0 required for peripheral myelin compaction J. Neurosci. 29 2009 6094 6104
-
(2009)
J. Neurosci.
, vol.29
, pp. 6094-6104
-
-
Saher, G.1
Quintes, S.2
Mobius, W.3
Wehr, M.C.4
Kramer-Albers, E.M.5
Brugger, B.6
Nave, K.A.7
-
59
-
-
84876967280
-
Reduction of the cholesterol sensor SCAP in the brains of mice causes impaired synaptic transmission and altered cognitive function
-
R. Suzuki, H.A. Ferris, M.J. Chee, E. Maratos-Flier, and C.R. Kahn Reduction of the cholesterol sensor SCAP in the brains of mice causes impaired synaptic transmission and altered cognitive function PLoS Biol. 11 2013 e1001532
-
(2013)
PLoS Biol.
, vol.11
, pp. 1001532
-
-
Suzuki, R.1
Ferris, H.A.2
Chee, M.J.3
Maratos-Flier, E.4
Kahn, C.R.5
-
60
-
-
0034669025
-
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta
-
J.J. Repa, G. Liang, J. Ou, Y. Bashmakov, J.M. Lobaccaro, I. Shimomura, B. Shan, M.S. Brown, J.L. Goldstein, and D.J. Mangelsdorf Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta Genes Dev. 14 2000 2819 2830
-
(2000)
Genes Dev.
, vol.14
, pp. 2819-2830
-
-
Repa, J.J.1
Liang, G.2
Ou, J.3
Bashmakov, Y.4
Lobaccaro, J.M.5
Shimomura, I.6
Shan, B.7
Brown, M.S.8
Goldstein, J.L.9
Mangelsdorf, D.J.10
-
61
-
-
79959938167
-
Interplay between LXR and Wnt/beta-catenin signaling in the negative regulation of peripheral myelin genes by oxysterols
-
J. Makoukji, G. Shackleford, D. Meffre, J. Grenier, P. Liere, J.M. Lobaccaro, M. Schumacher, and C. Massaad Interplay between LXR and Wnt/beta-catenin signaling in the negative regulation of peripheral myelin genes by oxysterols J. Neurosci. 31 2011 9620 9629
-
(2011)
J. Neurosci.
, vol.31
, pp. 9620-9629
-
-
Makoukji, J.1
Shackleford, G.2
Meffre, D.3
Grenier, J.4
Liere, P.5
Lobaccaro, J.M.6
Schumacher, M.7
Massaad, C.8
-
62
-
-
79953188349
-
Lipid metabolism in myelinating glial cells: Lessons from human inherited disorders and mouse models
-
R. Chrast, G. Saher, K.A. Nave, and M.H. Verheijen Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models J. Lipid Res. 52 2011 419 434
-
(2011)
J. Lipid Res.
, vol.52
, pp. 419-434
-
-
Chrast, R.1
Saher, G.2
Nave, K.A.3
Verheijen, M.H.4
-
63
-
-
0035821438
-
Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease
-
D.C. German, E.M. Quintero, C.L. Liang, B. Ng, S. Punia, C. Xie, and J.M. Dietschy Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease J. Comp. Neurol. 433 2001 415 425
-
(2001)
J. Comp. Neurol.
, vol.433
, pp. 415-425
-
-
German, D.C.1
Quintero, E.M.2
Liang, C.L.3
Ng, B.4
Punia, S.5
Xie, C.6
Dietschy, J.M.7
-
64
-
-
11144355005
-
Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport
-
D.E. Sleat, J.A. Wiseman, M. El-Banna, S.M. Price, L. Verot, M.M. Shen, G.S. Tint, M.T. Vanier, S.U. Walkley, and P. Lobel Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport Proc. Natl. Acad. Sci. U. S. A. 101 2004 5886 5891
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 5886-5891
-
-
Sleat, D.E.1
Wiseman, J.A.2
El-Banna, M.3
Price, S.M.4
Verot, L.5
Shen, M.M.6
Tint, G.S.7
Vanier, M.T.8
Walkley, S.U.9
Lobel, P.10
-
65
-
-
84876855611
-
Npc1 acting in neurons and glia is essential for the formation and maintenance of CNS myelin
-
T. Yu, and A.P. Lieberman Npc1 acting in neurons and glia is essential for the formation and maintenance of CNS myelin PLoS Genet. 9 2013 e1003462
-
(2013)
PLoS Genet.
, vol.9
, pp. 1003462
-
-
Yu, T.1
Lieberman, A.P.2
-
66
-
-
0023280054
-
Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B, E(LDL) receptors in the brain
-
R.E. Pitas, J.K. Boyles, S.H. Lee, D. Hui, and K.H. Weisgraber Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B, E(LDL) receptors in the brain J. Biol. Chem. 262 1987 14352 14360
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 14352-14360
-
-
Pitas, R.E.1
Boyles, J.K.2
Lee, S.H.3
Hui, D.4
Weisgraber, K.H.5
-
67
-
-
4644295495
-
Deficiency of ABCA1 impairs apolipoprotein e metabolism in brain
-
V. Hirsch-Reinshagen, S. Zhou, B.L. Burgess, L. Bernier, S.A. McIsaac, J.Y. Chan, G.H. Tansley, J.S. Cohn, M.R. Hayden, and C.L. Wellington Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain J. Biol. Chem. 279 2004 41197 41207
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 41197-41207
-
-
Hirsch-Reinshagen, V.1
Zhou, S.2
Burgess, B.L.3
Bernier, L.4
McIsaac, S.A.5
Chan, J.Y.6
Tansley, G.H.7
Cohn, J.S.8
Hayden, M.R.9
Wellington, C.L.10
-
68
-
-
63849221643
-
Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function
-
J.M. Karasinska, F. Rinninger, D. Lutjohann, P. Ruddle, S. Franciosi, J.K. Kruit, R.R. Singaraja, V. Hirsch-Reinshagen, J. Fan, L.R. Brunham, N. Bissada, R. Ramakrishnan, C.L. Wellington, J.S. Parks, and M.R. Hayden Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function J. Neurosci. 29 2009 3579 3589
-
(2009)
J. Neurosci.
, vol.29
, pp. 3579-3589
-
-
Karasinska, J.M.1
Rinninger, F.2
Lutjohann, D.3
Ruddle, P.4
Franciosi, S.5
Kruit, J.K.6
Singaraja, R.R.7
Hirsch-Reinshagen, V.8
Fan, J.9
Brunham, L.R.10
Bissada, N.11
Ramakrishnan, R.12
Wellington, C.L.13
Parks, J.S.14
Hayden, M.R.15
-
70
-
-
0031031675
-
Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis
-
V. Papadopoulos, H. Amri, N. Boujrad, C. Cascio, M. Culty, M. Garnier, M. Hardwick, H. Li, B. Vidic, A.S. Brown, J.L. Reversa, J.M. Bernassau, and K. Drieu Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis Steroids 62 1997 21 28
-
(1997)
Steroids
, vol.62
, pp. 21-28
-
-
Papadopoulos, V.1
Amri, H.2
Boujrad, N.3
Cascio, C.4
Culty, M.5
Garnier, M.6
Hardwick, M.7
Li, H.8
Vidic, B.9
Brown, A.S.10
Reversa, J.L.11
Bernassau, J.M.12
Drieu, K.13
-
71
-
-
84891379545
-
Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis
-
K. Morohaku, S.H. Pelton, D.J. Daugherty, W.R. Butler, W. Deng, and V. Selvaraj Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis Endocrinology 155 2014 89 97
-
(2014)
Endocrinology
, vol.155
, pp. 89-97
-
-
Morohaku, K.1
Pelton, S.H.2
Daugherty, D.J.3
Butler, W.R.4
Deng, W.5
Selvaraj, V.6
-
72
-
-
0030848810
-
Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia
-
K.M. Caron, S.C. Soo, W.C. Wetsel, D.M. Stocco, B.J. Clark, and K.L. Parker Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia Proc. Natl. Acad. Sci. U. S. A. 94 1997 11540 11545
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 11540-11545
-
-
Caron, K.M.1
Soo, S.C.2
Wetsel, W.C.3
Stocco, D.M.4
Clark, B.J.5
Parker, K.L.6
-
73
-
-
0026665062
-
Steroidogenic factor I, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu-factor i
-
D.S. Lala, D.A. Rice, and K.L. Parker Steroidogenic factor I, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu-factor I Mol. Endocrinol. 6 1992 1249 1258
-
(1992)
Mol. Endocrinol.
, vol.6
, pp. 1249-1258
-
-
Lala, D.S.1
Rice, D.A.2
Parker, K.L.3
-
74
-
-
0026640265
-
A common trans-acting factor, Ad4-binding protein, to the promoters of steroidogenic P-450 s
-
K. Morohashi, S. Honda, Y. Inomata, H. Handa, and T. Omura A common trans-acting factor, Ad4-binding protein, to the promoters of steroidogenic P-450 s J. Biol. Chem. 267 1992 17913 17919
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17913-17919
-
-
Morohashi, K.1
Honda, S.2
Inomata, Y.3
Handa, H.4
Omura, T.5
-
75
-
-
44649177751
-
Central nervous system-specific knockout of steroidogenic factor 1 results in increased anxiety-like behavior
-
L. Zhao, K.W. Kim, Y. Ikeda, K.K. Anderson, L. Beck, S. Chase, S.A. Tobet, and K.L. Parker Central nervous system-specific knockout of steroidogenic factor 1 results in increased anxiety-like behavior Mol. Endocrinol. 22 2008 1403 1415
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 1403-1415
-
-
Zhao, L.1
Kim, K.W.2
Ikeda, Y.3
Anderson, K.K.4
Beck, L.5
Chase, S.6
Tobet, S.A.7
Parker, K.L.8
-
76
-
-
33644868456
-
Brain cholesterol turnover required for geranylgeraniol production and learning in mice
-
T.J. Kotti, D.M. Ramirez, B.E. Pfeiffer, K.M. Huber, and D.W. Russell Brain cholesterol turnover required for geranylgeraniol production and learning in mice Proc. Natl. Acad. Sci. U. S. A. 103 2006 3869 3874
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 3869-3874
-
-
Kotti, T.J.1
Ramirez, D.M.2
Pfeiffer, B.E.3
Huber, K.M.4
Russell, D.W.5
-
77
-
-
0023389399
-
Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin
-
K.A. Nave, C. Lai, F.E. Bloom, and R.J. Milner Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin Proc. Natl. Acad. Sci. U. S. A. 84 1987 5665 5669
-
(1987)
Proc. Natl. Acad. Sci. U. S. A.
, vol.84
, pp. 5665-5669
-
-
Nave, K.A.1
Lai, C.2
Bloom, F.E.3
Milner, R.J.4
-
78
-
-
0031037761
-
Assembly of CNS myelin in the absence of proteolipid protein
-
M. Klugmann, M.H. Schwab, A. Puhlhofer, A. Schneider, F. Zimmermann, I.R. Griffiths, and K.A. Nave Assembly of CNS myelin in the absence of proteolipid protein Neuron 18 1997 59 70
-
(1997)
Neuron
, vol.18
, pp. 59-70
-
-
Klugmann, M.1
Schwab, M.H.2
Puhlhofer, A.3
Schneider, A.4
Zimmermann, F.5
Griffiths, I.R.6
Nave, K.A.7
-
79
-
-
84873721021
-
A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system
-
H.B. Werner, E.M. Kramer-Albers, N. Strenzke, G. Saher, S. Tenzer, Y. Ohno-Iwashita, P. De Monasterio-Schrader, W. Mobius, T. Moser, I.R. Griffiths, and K.A. Nave A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system Glia 61 2013 567 586
-
(2013)
Glia
, vol.61
, pp. 567-586
-
-
Werner, H.B.1
Kramer-Albers, E.M.2
Strenzke, N.3
Saher, G.4
Tenzer, S.5
Ohno-Iwashita, Y.6
De Monasterio-Schrader, P.7
Mobius, W.8
Moser, T.9
Griffiths, I.R.10
Nave, K.A.11
-
80
-
-
15844393894
-
A transgenic rat model of Charcot-Marie-Tooth disease
-
M. Sereda, I. Griffiths, A. Puhlhofer, H. Stewart, M.J. Rossner, F. Zimmerman, J.P. Magyar, A. Schneider, E. Hund, H.M. Meinck, U. Suter, and K.A. Nave A transgenic rat model of Charcot-Marie-Tooth disease Neuron 16 1996 1049 1060
-
(1996)
Neuron
, vol.16
, pp. 1049-1060
-
-
Sereda, M.1
Griffiths, I.2
Puhlhofer, A.3
Stewart, H.4
Rossner, M.J.5
Zimmerman, F.6
Magyar, J.P.7
Schneider, A.8
Hund, E.9
Meinck, H.M.10
Suter, U.11
Nave, K.A.12
-
81
-
-
0028784820
-
Hypermyelination and demyelinating peripheral neuropathy in Pmp22-deficient mice
-
K. Adlkofer, R. Martini, A. Aguzzi, J. Zielasek, K.V. Toyka, and U. Suter Hypermyelination and demyelinating peripheral neuropathy in Pmp22-deficient mice Nat. Genet. 11 1995 274 280
-
(1995)
Nat. Genet.
, vol.11
, pp. 274-280
-
-
Adlkofer, K.1
Martini, R.2
Aguzzi, A.3
Zielasek, J.4
Toyka, K.V.5
Suter, U.6
-
82
-
-
0028824925
-
Protein zero (P0)-deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies
-
R. Martini, J. Zielasek, K.V. Toyka, K.P. Giese, and M. Schachner Protein zero (P0)-deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies Nat. Genet. 11 1995 281 286
-
(1995)
Nat. Genet.
, vol.11
, pp. 281-286
-
-
Martini, R.1
Zielasek, J.2
Toyka, K.V.3
Giese, K.P.4
Schachner, M.5
-
83
-
-
0034611010
-
P(0) glycoprotein overexpression causes congenital hypomyelination of peripheral nerves
-
L. Wrabetz, M.L. Feltri, A. Quattrini, D. Imperiale, S. Previtali, M. D'Antonio, R. Martini, X. Yin, B.D. Trapp, L. Zhou, S.Y. Chiu, and A. Messing P(0) glycoprotein overexpression causes congenital hypomyelination of peripheral nerves J. Cell Biol. 148 2000 1021 1034
-
(2000)
J. Cell Biol.
, vol.148
, pp. 1021-1034
-
-
Wrabetz, L.1
Feltri, M.L.2
Quattrini, A.3
Imperiale, D.4
Previtali, S.5
D'Antonio, M.6
Martini, R.7
Yin, X.8
Trapp, B.D.9
Zhou, L.10
Chiu, S.Y.11
Messing, A.12
-
84
-
-
0021285554
-
Ultrastructural localization of P2 protein in actively myelinating rat Schwann cells
-
B.D. Trapp, M. Dubois-Dalcq, and R.H. Quarles Ultrastructural localization of P2 protein in actively myelinating rat Schwann cells J. Neurochem. 43 1984 944 948
-
(1984)
J. Neurochem.
, vol.43
, pp. 944-948
-
-
Trapp, B.D.1
Dubois-Dalcq, M.2
Quarles, R.H.3
-
85
-
-
77951247968
-
Myelin basic protein and myelin protein 2 act synergistically to cause stacking of lipid bilayers
-
S. Suresh, C. Wang, R. Nanekar, P. Kursula, and J.M. Edwardson Myelin basic protein and myelin protein 2 act synergistically to cause stacking of lipid bilayers Biochemistry 49 2010 3456 3463
-
(2010)
Biochemistry
, vol.49
, pp. 3456-3463
-
-
Suresh, S.1
Wang, C.2
Nanekar, R.3
Kursula, P.4
Edwardson, J.M.5
-
86
-
-
84904310811
-
A role of peripheral myelin protein 2 in lipid homeostasis of myelinating Schwann cells
-
J. Zenker, M. Stettner, S. Ruskamo, E. Domenech-Estevez, H. Baloui, J.J. Medard, M.H. Verheijen, J.F. Brouwers, P. Kursula, B.C. Kieseier, and R. Chrast A role of peripheral myelin protein 2 in lipid homeostasis of myelinating Schwann cells Glia 62 9 2014 1502 1512
-
(2014)
Glia
, vol.62
, Issue.9
, pp. 1502-1512
-
-
Zenker, J.1
Stettner, M.2
Ruskamo, S.3
Domenech-Estevez, E.4
Baloui, H.5
Medard, J.J.6
Verheijen, M.H.7
Brouwers, J.F.8
Kursula, P.9
Kieseier, B.C.10
Chrast, R.11
-
87
-
-
0035869221
-
Biochemical, phenotypic and neurophysiological characterization of a genetic mouse model of RSH/Smith-Lemli-Opitz syndrome
-
C.A. Wassif, P. Zhu, L. Kratz, P.A. Krakowiak, K.P. Battaile, F.F. Weight, A. Grinberg, R.D. Steiner, N.A. Nwokoro, R.I. Kelley, R.R. Stewart, and F.D. Porter Biochemical, phenotypic and neurophysiological characterization of a genetic mouse model of RSH/Smith-Lemli-Opitz syndrome Hum. Mol. Genet. 10 2001 555 564
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 555-564
-
-
Wassif, C.A.1
Zhu, P.2
Kratz, L.3
Krakowiak, P.A.4
Battaile, K.P.5
Weight, F.F.6
Grinberg, A.7
Steiner, R.D.8
Nwokoro, N.A.9
Kelley, R.I.10
Stewart, R.R.11
Porter, F.D.12
-
88
-
-
33644769281
-
Development and characterization of a hypomorphic Smith-Lemli-Opitz syndrome mouse model and efficacy of simvastatin therapy
-
L.S. Correa-Cerro, C.A. Wassif, L. Kratz, G.F. Miller, J.P. Munasinghe, A. Grinberg, S.J. Fliesler, and F.D. Porter Development and characterization of a hypomorphic Smith-Lemli-Opitz syndrome mouse model and efficacy of simvastatin therapy Hum. Mol. Genet. 15 2006 839 851
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 839-851
-
-
Correa-Cerro, L.S.1
Wassif, C.A.2
Kratz, L.3
Miller, G.F.4
Munasinghe, J.P.5
Grinberg, A.6
Fliesler, S.J.7
Porter, F.D.8
-
89
-
-
74049132805
-
Niemann-Pick disease type C: From molecule to clinic
-
Y. Tang, H. Li, and J.P. Liu Niemann-Pick disease type C: from molecule to clinic Clin. Exp. Pharmacol. Physiol. 37 2010 132 140
-
(2010)
Clin. Exp. Pharmacol. Physiol.
, vol.37
, pp. 132-140
-
-
Tang, Y.1
Li, H.2
Liu, J.P.3
-
90
-
-
84883877051
-
Genetic dissection of a cell-autonomous neurodegenerative disorder: Lessons learned from mouse models of Niemann-Pick disease type C
-
M.E. Lopez, and M.P. Scott Genetic dissection of a cell-autonomous neurodegenerative disorder: lessons learned from mouse models of Niemann-Pick disease type C Dis. Model. Mech. 6 2013 1089 1100
-
(2013)
Dis. Model. Mech.
, vol.6
, pp. 1089-1100
-
-
Lopez, M.E.1
Scott, M.P.2
-
91
-
-
84863022173
-
A novel mouse model of Niemann-Pick type C disease carrying a D1005G-Npc1 mutation comparable to commonly observed human mutations
-
R.A. Maue, R.W. Burgess, B. Wang, C.M. Wooley, K.L. Seburn, M.T. Vanier, M.A. Rogers, C.C. Chang, T.Y. Chang, B.T. Harris, D.J. Graber, C.A. Penatti, D.M. Porter, B.S. Szwergold, L.P. Henderson, J.W. Totenhagen, T.P. Trouard, I.A. Borbon, and R.P. Erickson A novel mouse model of Niemann-Pick type C disease carrying a D1005G-Npc1 mutation comparable to commonly observed human mutations Hum. Mol. Genet. 21 2012 730 750
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 730-750
-
-
Maue, R.A.1
Burgess, R.W.2
Wang, B.3
Wooley, C.M.4
Seburn, K.L.5
Vanier, M.T.6
Rogers, M.A.7
Chang, C.C.8
Chang, T.Y.9
Harris, B.T.10
Graber, D.J.11
Penatti, C.A.12
Porter, D.M.13
Szwergold, B.S.14
Henderson, L.P.15
Totenhagen, J.W.16
Trouard, T.P.17
Borbon, I.A.18
Erickson, R.P.19
-
92
-
-
0032813808
-
Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency
-
A. Brooks-Wilson, M. Marcil, S.M. Clee, L.H. Zhang, K. Roomp, M. van Dam, L. Yu, C. Brewer, J.A. Collins, H.O. Molhuizen, O. Loubser, B.F. Ouelette, K. Fichter, K.J. Ashbourne-Excoffon, C.W. Sensen, S. Scherer, S. Mott, M. Denis, D. Martindale, J. Frohlich, K. Morgan, B. Koop, S. Pimstone, J.J. Kastelein, J. Genest Jr., and M.R. Hayden Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency Nat. Genet. 22 1999 336 345
-
(1999)
Nat. Genet.
, vol.22
, pp. 336-345
-
-
Brooks-Wilson, A.1
Marcil, M.2
Clee, S.M.3
Zhang, L.H.4
Roomp, K.5
Van Dam, M.6
Yu, L.7
Brewer, C.8
Collins, J.A.9
Molhuizen, H.O.10
Loubser, O.11
Ouelette, B.F.12
Fichter, K.13
Ashbourne-Excoffon, K.J.14
Sensen, C.W.15
Scherer, S.16
Mott, S.17
Denis, M.18
Martindale, D.19
Frohlich, J.20
Morgan, K.21
Koop, B.22
Pimstone, S.23
Kastelein, J.J.24
Genest, J.25
Hayden, M.R.26
more..
-
93
-
-
0033576209
-
Mutations in the ABC1 gene in familial HDL deficiency with defective cholesterol efflux
-
M. Marcil, A. Brooks-Wilson, S.M. Clee, K. Roomp, L.H. Zhang, L. Yu, J.A. Collins, M. van Dam, H.O. Molhuizen, O. Loubster, B.F. Ouellette, C.W. Sensen, K. Fichter, S. Mott, M. Denis, B. Boucher, S. Pimstone, J. Genest Jr., J.J. Kastelein, and M.R. Hayden Mutations in the ABC1 gene in familial HDL deficiency with defective cholesterol efflux Lancet 354 1999 1341 1346
-
(1999)
Lancet
, vol.354
, pp. 1341-1346
-
-
Marcil, M.1
Brooks-Wilson, A.2
Clee, S.M.3
Roomp, K.4
Zhang, L.H.5
Yu, L.6
Collins, J.A.7
Van Dam, M.8
Molhuizen, H.O.9
Loubster, O.10
Ouellette, B.F.11
Sensen, C.W.12
Fichter, K.13
Mott, S.14
Denis, M.15
Boucher, B.16
Pimstone, S.17
Genest, J.18
Kastelein, J.J.19
Hayden, M.R.20
more..
-
94
-
-
0342811295
-
Human ATP-binding cassette transporter 1 (ABC1): Genomic organization and identification of the genetic defect in the original Tangier disease kindred
-
A.T. Remaley, S. Rust, M. Rosier, C. Knapper, L. Naudin, C. Broccardo, K.M. Peterson, C. Koch, I. Arnould, C. Prades, N. Duverger, H. Funke, G. Assman, M. Dinger, M. Dean, G. Chimini, S. Santamarina-Fojo, D.S. Fredrickson, P. Denefle, and H.B. Brewer Jr. Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindred Proc. Natl. Acad. Sci. U. S. A. 96 1999 12685 12690
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 12685-12690
-
-
Remaley, A.T.1
Rust, S.2
Rosier, M.3
Knapper, C.4
Naudin, L.5
Broccardo, C.6
Peterson, K.M.7
Koch, C.8
Arnould, I.9
Prades, C.10
Duverger, N.11
Funke, H.12
Assman, G.13
Dinger, M.14
Dean, M.15
Chimini, G.16
Santamarina-Fojo, S.17
Fredrickson, D.S.18
Denefle, P.19
Brewer, H.B.20
more..
-
95
-
-
0032813660
-
Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
-
S. Rust, M. Rosier, H. Funke, J. Real, Z. Amoura, J.C. Piette, J.F. Deleuze, H.B. Brewer, N. Duverger, P. Denefle, and G. Assmann Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1 Nat. Genet. 22 1999 352 355
-
(1999)
Nat. Genet.
, vol.22
, pp. 352-355
-
-
Rust, S.1
Rosier, M.2
Funke, H.3
Real, J.4
Amoura, Z.5
Piette, J.C.6
Deleuze, J.F.7
Brewer, H.B.8
Duverger, N.9
Denefle, P.10
Assmann, G.11
-
97
-
-
0034490992
-
Functional loss of ABCA1 in mice causes severe placental malformation, aberrant lipid distribution, and kidney glomerulonephritis as well as high-density lipoprotein cholesterol deficiency
-
T.A. Christiansen-Weber, J.R. Voland, Y. Wu, K. Ngo, B.L. Roland, S. Nguyen, P.A. Peterson, and W.P. Fung-Leung Functional loss of ABCA1 in mice causes severe placental malformation, aberrant lipid distribution, and kidney glomerulonephritis as well as high-density lipoprotein cholesterol deficiency Am. J. Pathol. 157 2000 1017 1029
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 1017-1029
-
-
Christiansen-Weber, T.A.1
Voland, J.R.2
Wu, Y.3
Ngo, K.4
Roland, B.L.5
Nguyen, S.6
Peterson, P.A.7
Fung-Leung, W.P.8
-
98
-
-
84870002036
-
Dysregulation of cholesterol balance in the brain: Contribution to neurodegenerative diseases
-
J.E. Vance Dysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseases Dis. Model. Mech. 5 2012 746 755
-
(2012)
Dis. Model. Mech.
, vol.5
, pp. 746-755
-
-
Vance, J.E.1
-
99
-
-
84855697856
-
Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: Protective effects of LXR activation
-
G. Cermenati, F. Abbiati, S. Cermenati, E. Brioschi, A. Volonterio, G. Cavaletti, E. Saez, E. De Fabiani, M. Crestani, L.M. Garcia-Segura, R.C. Melcangi, D. Caruso, and N. Mitro Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation J. Lipid Res. 53 2012 300 310
-
(2012)
J. Lipid Res.
, vol.53
, pp. 300-310
-
-
Cermenati, G.1
Abbiati, F.2
Cermenati, S.3
Brioschi, E.4
Volonterio, A.5
Cavaletti, G.6
Saez, E.7
De Fabiani, E.8
Crestani, M.9
Garcia-Segura, L.M.10
Melcangi, R.C.11
Caruso, D.12
Mitro, N.13
-
100
-
-
84873429169
-
Nutrition and neurodegeneration: Epidemiological evidence and challenges for future research
-
S. Gillette-Guyonnet, M. Secher, and B. Vellas Nutrition and neurodegeneration: epidemiological evidence and challenges for future research Br. J. Clin. Pharmacol. 75 2013 738 755
-
(2013)
Br. J. Clin. Pharmacol.
, vol.75
, pp. 738-755
-
-
Gillette-Guyonnet, S.1
Secher, M.2
Vellas, B.3
-
101
-
-
17844380480
-
Peripheral nerves: A target for the action of neuroactive steroids
-
R.C. Melcangi, I.T. Cavarretta, M. Ballabio, E. Leonelli, A. Schenone, I. Azcoitia, L. Miguel Garcia-Segura, and V. Magnaghi Peripheral nerves: a target for the action of neuroactive steroids Brain Res. Brain Res. Rev. 48 2005 328 338
-
(2005)
Brain Res. Brain Res. Rev.
, vol.48
, pp. 328-338
-
-
Melcangi, R.C.1
Cavarretta, I.T.2
Ballabio, M.3
Leonelli, E.4
Schenone, A.5
Azcoitia, I.6
Miguel Garcia-Segura, L.7
Magnaghi, V.8
-
102
-
-
33747153332
-
Therapeutic approaches to peripheral neuropathy based on neuroactive steroids
-
R.C. Melcangi, and L.M. Garcia-Segura Therapeutic approaches to peripheral neuropathy based on neuroactive steroids Expert. Rev. Neurother. 6 2006 1121 1125
-
(2006)
Expert. Rev. Neurother.
, vol.6
, pp. 1121-1125
-
-
Melcangi, R.C.1
Garcia-Segura, L.M.2
-
103
-
-
38349123293
-
Evaluation of neuroactive steroid levels by liquid chromatography-tandem mass spectrometry in central and peripheral nervous system: Effect of diabetes
-
D. Caruso, S. Scurati, O. Maschi, L. De Angelis, I. Roglio, S. Giatti, L.M. Garcia-Segura, and R.C. Melcangi Evaluation of neuroactive steroid levels by liquid chromatography-tandem mass spectrometry in central and peripheral nervous system: effect of diabetes Neurochem. Int. 52 2008 560 568
-
(2008)
Neurochem. Int.
, vol.52
, pp. 560-568
-
-
Caruso, D.1
Scurati, S.2
Maschi, O.3
De Angelis, L.4
Roglio, I.5
Giatti, S.6
Garcia-Segura, L.M.7
Melcangi, R.C.8
-
104
-
-
73049086234
-
Sex differences in neuroactive steroid levels in the nervous system of diabetic and non-diabetic rats
-
M. Pesaresi, O. Maschi, S. Giatti, L.M. Garcia-Segura, D. Caruso, and R.C. Melcangi Sex differences in neuroactive steroid levels in the nervous system of diabetic and non-diabetic rats Horm. Behav. 57 2010 46 55
-
(2010)
Horm. Behav.
, vol.57
, pp. 46-55
-
-
Pesaresi, M.1
Maschi, O.2
Giatti, S.3
Garcia-Segura, L.M.4
Caruso, D.5
Melcangi, R.C.6
-
105
-
-
84892872626
-
Levels and actions of progesterone and its metabolites in the nervous system during physiological and pathological conditions
-
R.C. Melcangi, S. Giatti, D. Calabrese, M. Pesaresi, G. Cermenati, N. Mitro, B. Viviani, L.M. Garcia-Segura, and D. Caruso Levels and actions of progesterone and its metabolites in the nervous system during physiological and pathological conditions Prog. Neurobiol. 113 2014 56 69
-
(2014)
Prog. Neurobiol.
, vol.113
, pp. 56-69
-
-
Melcangi, R.C.1
Giatti, S.2
Calabrese, D.3
Pesaresi, M.4
Cermenati, G.5
Mitro, N.6
Viviani, B.7
Garcia-Segura, L.M.8
Caruso, D.9
-
106
-
-
0036839174
-
Effect of treatment of diabetic rats with dehydroepiandrosterone on vascular and neural function
-
M.A. Yorek, L.J. Coppey, J.S. Gellett, E.P. Davidson, X. Bing, D.D. Lund, and J.S. Dillon Effect of treatment of diabetic rats with dehydroepiandrosterone on vascular and neural function Am. J. Physiol. Endocrinol. Metab. 283 2002 E1067 E1075
-
(2002)
Am. J. Physiol. Endocrinol. Metab.
, vol.283
, pp. 1067-E1075
-
-
Yorek, M.A.1
Coppey, L.J.2
Gellett, J.S.3
Davidson, E.P.4
Bing, X.5
Lund, D.D.6
Dillon, J.S.7
-
107
-
-
38549181078
-
Neurosteroids: Measurement and pathophysiologic relevance
-
R.C. Melcangi, and A.G. Mensah-Nyagan Neurosteroids: measurement and pathophysiologic relevance Neurochem. Int. 52 2008 503 505
-
(2008)
Neurochem. Int.
, vol.52
, pp. 503-505
-
-
Melcangi, R.C.1
Mensah-Nyagan, A.G.2
-
108
-
-
70349742796
-
Neuroprotective effects of a ligand of translocator protein-18 kDa (Ro5-4864) in experimental diabetic neuropathy
-
S. Giatti, M. Pesaresi, G. Cavaletti, R. Bianchi, V. Carozzi, R. Lombardi, O. Maschi, G. Lauria, L.M. Garcia-Segura, D. Caruso, and R.C. Melcangi Neuroprotective effects of a ligand of translocator protein-18 kDa (Ro5-4864) in experimental diabetic neuropathy Neuroscience 164 2009 520 529
-
(2009)
Neuroscience
, vol.164
, pp. 520-529
-
-
Giatti, S.1
Pesaresi, M.2
Cavaletti, G.3
Bianchi, R.4
Carozzi, V.5
Lombardi, R.6
Maschi, O.7
Lauria, G.8
Garcia-Segura, L.M.9
Caruso, D.10
Melcangi, R.C.11
-
109
-
-
77956578447
-
Activation of the liver X receptor increases neuroactive steroid levels and protects from diabetes-induced peripheral neuropathy
-
G. Cermenati, S. Giatti, G. Cavaletti, R. Bianchi, O. Maschi, M. Pesaresi, F. Abbiati, A. Volonterio, E. Saez, D. Caruso, R.C. Melcangi, and N. Mitro Activation of the liver X receptor increases neuroactive steroid levels and protects from diabetes-induced peripheral neuropathy J. Neurosci. 30 2010 11896 11901
-
(2010)
J. Neurosci.
, vol.30
, pp. 11896-11901
-
-
Cermenati, G.1
Giatti, S.2
Cavaletti, G.3
Bianchi, R.4
Maschi, O.5
Pesaresi, M.6
Abbiati, F.7
Volonterio, A.8
Saez, E.9
Caruso, D.10
Melcangi, R.C.11
Mitro, N.12
-
110
-
-
84899150858
-
Unintended effects of statins from observational studies in the general population: Systematic review and meta-analysis
-
A.F. Macedo, F.C. Taylor, J.P. Casas, A. Adler, D. Prieto-Merino, and S. Ebrahim Unintended effects of statins from observational studies in the general population: systematic review and meta-analysis BMC Med. 12 2014 51
-
(2014)
BMC Med.
, vol.12
, pp. 51
-
-
MacEdo, A.F.1
Taylor, F.C.2
Casas, J.P.3
Adler, A.4
Prieto-Merino, D.5
Ebrahim, S.6
|