Activation of the liver X receptor increases neuroactive steroid levels and protects from diabetes-induced peripheral neuropathy

Journal of Neuroscience

Volumn 30, Issue 36, 2010, Pages 11896-11901

  Cermenati, Gaia ^a   Giatti, Silvia ^a   Cavaletti, Guido ^b   Bianchi, Roberto ^c   Maschi, Omar ^a   Pesaresi, Marzia ^a   Abbiati, Federico ^a   Volonterio, Alessandro ^d   Saez, Enrique ^e   Caruso, Donatella ^a   Melcangi, Roberto Cosimo ^a   Mitro, Nico ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

^c DEPARTMENT OF NEUROSURGERY   (Italy)

^d POLITECNICO DI MILANO   (Italy)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

20ALPHA DIHYDROPROGESTERONE; ABC TRANSPORTER A1; ABC TRANSPORTER G1; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CELL NUCLEUS RECEPTOR; CHOLESTEROL; CYTOCHROME P450; LIVER X RECEPTOR; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; NEUROSTEROID; PREGNENOLONE; PROGESTERONE; REGULATOR PROTEIN; STEROID 5ALPHA REDUCTASE; STREPTOZOCIN; 3 [3 [[2 CHLORO 3 (TRIFLUOROMETHYL)BENZYL](2 DIPHENYLETHYL)AMINO]PROPOXY]PHENYLACETIC ACID; BENZOIC ACID DERIVATIVE; BENZYLAMINE DERIVATIVE; LIGAND; MYELIN PROTEIN; ORPHAN NUCLEAR RECEPTOR; STEROID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DIABETIC NEUROPATHY; ENZYME ACTIVITY; HOMEOSTASIS; MALE; NERVE CONDUCTION; NEUROPROTECTION; NOCICEPTION; NONHUMAN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; RAT; SCIATIC NERVE; STEROIDOGENESIS; VELOCITY; ANALYSIS OF VARIANCE; ANIMAL; BODY WEIGHT; COMPLICATION; DIABETIC NEUROPATHIES; DISEASE MODEL; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; HYPERALGESIA; LIQUID CHROMATOGRAPHY; METABOLISM; MICROBIOLOGY; PAIN THRESHOLD; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; SPRAGUE DAWLEY RAT; TANDEM MASS SPECTROMETRY;

ANALYSIS OF VARIANCE; ANIMALS; BENZOIC ACIDS; BENZYLAMINES; BODY WEIGHT; CHROMATOGRAPHY, LIQUID; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HYPERALGESIA; LIGANDS; MALE; MYELIN PROTEINS; NEURAL CONDUCTION; ORPHAN NUCLEAR RECEPTORS; PAIN THRESHOLD; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; SODIUM-POTASSIUM-EXCHANGING ATPASE; STEROIDS; TANDEM MASS SPECTROMETRY; BENZOATES;

EID: 77956578447     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1898-10.2010     Document Type: Article

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