High cholesterol level is essential for myelin membrane growth

Nature Neuroscience

Volumn 8, Issue 4, 2005, Pages 468-475

  Saher, Gesine ^a   Brügger, Britta ^b   Lappe Siefke, Corinna ^a   Möbius, Wiebke ^c   Tozawa, Ryu Ichi ^d   Wehr, Michael C ^a   Wieland, Felix ^b   Ishibashi, Shun ^e   Nave, Klaus Armin ^a,f  

^a MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d UNIVERSITY OF TOKYO   (Japan)

^e JICHI MEDICAL UNIVERSITY   (Japan)

^f Hertie Institute of Multiple Sclerosis Research   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; MYELIN; 2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; APOLIPOPROTEIN E; CREATINE; LOW DENSITY LIPOPROTEIN RECEPTOR; PROTEOLIPID PROTEIN; RNA; SQUALENE SYNTHASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN MATURATION; CELL SURVIVAL; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DEGENERATIVE DISEASE; MOUSE; MYELIN SHEATH; MYELINATION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RISK FACTOR; WILD TYPE; AGE; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; CELL MEMBRANE; CENTRAL NERVOUS SYSTEM; COMPARATIVE STUDY; GENE EXPRESSION REGULATION; GENETICS; IN SITU HYBRIDIZATION; LIPID METABOLISM; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; MICROSOME; MOLECULAR CLONING; MOUSE MUTANT; NEWBORN; NORTHERN BLOTTING; PHENOTYPE; PHYSIOLOGY; PSYCHOMOTOR PERFORMANCE; SILVER STAINING; SOUTHERN BLOTTING; SPINAL CORD; THIN LAYER CHROMATOGRAPHY; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; WESTERN BLOTTING;

2',3'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES; AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; APOLIPOPROTEINS E; BEHAVIOR, ANIMAL; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; BLOTTING, WESTERN; CELL MEMBRANE; CENTRAL NERVOUS SYSTEM; CHOLESTEROL; CHROMATOGRAPHY, THIN LAYER; CLONING, MOLECULAR; CREATINE; FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION; LIPID METABOLISM; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSOMES; MYELIN PROTEOLIPID PROTEIN; MYELIN SHEATH; OLIGODENDROGLIA; PHENOTYPE; PSYCHOMOTOR PERFORMANCE; RECEPTORS, LDL; RNA; SILVER STAINING; SPINAL CORD;

EID: 20044370505     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn1426     Document Type: Article

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