Levels and actions of progesterone and its metabolites in the nervous system during physiological and pathological conditions

Progress in Neurobiology

Volumn 113, Issue , 2014, Pages 56-69

  Melcangi, Roberto Cosimo ^a   Giatti, Silvia ^a   Calabrese, Donato ^a   Pesaresi, Marzia ^b   Cermenati, Gaia ^a   Mitro, Nico ^a   Viviani, Barbara ^a   Garcia Segura, Luis Miguel ^c   Caruso, Donatella ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b ROTMAN RESEARCH INSTITUTE   (Canada)

^c INSTITUTO CAJAL   (Spain)

Author keywords

Allopregnanolone; Gonadectomy; Metabolism; Neuroactive steroids; Neurodegeneration; Neuroprotection

Indexed keywords

PROGESTERONE; PROGESTERONE DERIVATIVE;

ALZHEIMER DISEASE; BRAIN DISEASE; CENTRAL NERVOUS SYSTEM; DIABETES MELLITUS; DIABETIC ENCEPHALOPATHY; HUMAN; MULTIPLE SCLEROSIS; NERVOUS SYSTEM; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PERIPHERAL NERVOUS SYSTEM; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROGESTERONE METABOLISM; PROGESTERONE SYNTHESIS; REVIEW;

3Α,5Α-TETRAHYDROPROGESTERONE; 3Α-HSOR; 3Α-HYDROXYSTEROID OXIDOREDUCTASE; 3Α-THP; 3Β,5Α-TETRAHYDROPROGESTERONE; 3Β-HSD; 3Β-HSOR; 3Β-HYDROXYSTEROID DEHYDROGENASE; 3Β-HYDROXYSTEROID OXIDOREDUCTASE; 3Β-THP; 5Α-R; 5Α-REDUCTASE; ALLOPREGNANOLONE; CENTRAL NERVOUS SYSTEM; CNS; DHP; DIHYDROPROGESTERONE; EAE; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; GLYCOPROTEIN ZERO; GONADECTOMY; IBA1; IONIZED CALCIUM-BINDING ADAPTER MOLECULE 1; LC-MS/MS; LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY; LIVER X RECEPTOR; LXR; MBP; METABOLISM; MYELIN BASIC PROTEIN; NEUROACTIVE STEROIDS; NEURODEGENERATION; NEUROPROTECTION; P0; P450 SIDE-CHAIN CLEAVAGE ENZYME; P450SCC; PERIPHERAL MYELIN PROTEIN 22; PERIPHERAL NERVOUS SYSTEM; PMP22; PNS; PR; PREG; PREGNENOLONE; PROG; PROGESTERONE; PROGESTERONE RECEPTOR; STAR; STEROIDOGENIC ACUTE REGULATORY PROTEIN; STREPTOZOTOCIN; STZ; TRANSLOCATOR PROTEIN OF 18 KDA; TSPO; WILD TYPE; WT;

ANIMALS; FEMALE; HUMANS; MALE; NERVOUS SYSTEM; NEURODEGENERATIVE DISEASES; PROGESTERONE; SEX CHARACTERISTICS;

EID: 84892872626     PISSN: 03010082     EISSN: 18735118     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2013.07.006     Document Type: Review

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