Suppression of amyloid-β production by 24S-hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking

FASEB Journal

Volumn 27, Issue 10, 2013, Pages 4305-4315

  Urano, Yasuomi ^a   Ochiai, Sachika ^a   Noguchi, Noriko ^a  

^a DOSHISHA UNIVERSITY   (Japan)

Author keywords

Alzheimer's disease; ER stress; Oxysterol; Vesicular transport

Indexed keywords

24 HYDROXYCHOLESTEROL; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CHAPERONE; CHOLESTEROL DERIVATIVE; COAT PROTEIN COMPLEX II; GLUCOSE REGULATED PROTEIN 78; SECRETASE; UNCLASSIFIED DRUG; 24-HYDROXYCHOLESTEROL; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; BRAIN HOMOGENATE; CELL ASSAY; CELL BUDDING; CELL LEVEL; CHO CELL; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; IC 50; IMMUNOBLOTTING; IN VITRO STUDY; INHIBITION KINETICS; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; PROTEOMICS; UNFOLDED PROTEIN RESPONSE; ANIMAL; CELL LINE; GENETICS; HAMSTER; METABOLISM; MOUSE; PHYSIOLOGY;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL LINE; CRICETINAE; HEAT-SHOCK PROTEINS; HUMANS; HYDROXYCHOLESTEROLS; MICE; PROTEIN BINDING; PROTEIN TRANSPORT;

EID: 84885165023     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-231456     Document Type: Article

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