메뉴 건너뛰기




Volumn 10, Issue 2, 2007, Pages 136-141

Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection

Author keywords

Alzheimer's disease; Neuroprotectin D1; Retinal pigment epithelium; Stroke

Indexed keywords

ACETYLSALICYLIC ACID; AMYLOID BETA PROTEIN[1-40]; CYCLOOXYGENASE 2; DOCOSAHEXAENOIC ACID; NEUROPROTECTIN D1; NEUROPROTECTIVE AGENT; OMEGA 3 FATTY ACID; PROTEIN; UNCLASSIFIED DRUG;

EID: 33846857139     PISSN: 13631950     EISSN: 15353885     Source Type: Journal    
DOI: 10.1097/MCO.0b013e32802b7030     Document Type: Review
Times cited : (211)

References (56)
  • 1
    • 0023243759 scopus 로고
    • Effect of bicuculline-induced status epilepticus on prostaglandins and hydroxyeicosatetraenoic acids in rat brain subcellular fractions
    • Birkle DL, Bazan NG. Effect of bicuculline-induced status epilepticus on prostaglandins and hydroxyeicosatetraenoic acids in rat brain subcellular fractions. J Neurochem 1987; 48:1768-1778.
    • (1987) J Neurochem , vol.48 , pp. 1768-1778
    • Birkle, D.L.1    Bazan, N.G.2
  • 2
    • 0016791370 scopus 로고
    • Differential lipid deacylation during brain ischemia in a homeotherm and a poikilotherm: Content and composition of free fatty acids and triacylglycerols
    • Aveldano MI, Bazan NG. Differential lipid deacylation during brain ischemia in a homeotherm and a poikilotherm: content and composition of free fatty acids and triacylglycerols. Brain Res 1975; 100:99-110.
    • (1975) Brain Res , vol.100 , pp. 99-110
    • Aveldano, M.I.1    Bazan, N.G.2
  • 3
    • 0039369595 scopus 로고
    • Membrane docosahexaenoate is supplied to the developing brain and retina by the liver
    • Scott BL, Bazan NG. Membrane docosahexaenoate is supplied to the developing brain and retina by the liver. Proc Natl Acad Sci U S A 1989; 86:2903-2907.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 2903-2907
    • Scott, B.L.1    Bazan, N.G.2
  • 4
    • 0033059809 scopus 로고    scopus 로고
    • Chronic administration of docosahexaenoic acid improves reference memory-related learning ability in young rats
    • Gamoh S, Hashimoto M, Sugioka K, et al. Chronic administration of docosahexaenoic acid improves reference memory-related learning ability in young rats. Neuroscience 1999; 93:237-241.
    • (1999) Neuroscience , vol.93 , pp. 237-241
    • Gamoh, S.1    Hashimoto, M.2    Sugioka, K.3
  • 5
    • 0032883405 scopus 로고    scopus 로고
    • Age-related changes in synaptic function: Analysis of the effect of dietary supplementation with omega-3 fatty acids
    • McGahon BM, Martin DS, Horrobin DF, et al. Age-related changes in synaptic function: analysis of the effect of dietary supplementation with omega-3 fatty acids. Neuroscience 1999; 94:305-314.
    • (1999) Neuroscience , vol.94 , pp. 305-314
    • McGahon, B.M.1    Martin, D.S.2    Horrobin, D.F.3
  • 6
    • 0025456810 scopus 로고
    • Docosahexaenoic acid utilization during rod photo-receptor cell renewal
    • Gordon WC, Bazan NG. Docosahexaenoic acid utilization during rod photo-receptor cell renewal. J Neurosci 1990; 10:2190-2202.
    • (1990) J Neurosci , vol.10 , pp. 2190-2202
    • Gordon, W.C.1    Bazan, N.G.2
  • 7
    • 0035815742 scopus 로고    scopus 로고
    • Protein kinase inhibition by omega-3 fatty acids
    • Mirnikjoo B, Brown SE, Kim HF, et al. Protein kinase inhibition by omega-3 fatty acids. J Biol Chem 2001; 276:10888-10896.
    • (2001) J Biol Chem , vol.276 , pp. 10888-10896
    • Mirnikjoo, B.1    Brown, S.E.2    Kim, H.F.3
  • 8
    • 0034678889 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids are potent neuroprotectors
    • Lauritzen I, Blondeau N, Heurteaux C, et al. Polyunsaturated fatty acids are potent neuroprotectors. EMBO J 2000; 19:1784-1793.
    • (2000) EMBO J , vol.19 , pp. 1784-1793
    • Lauritzen, I.1    Blondeau, N.2    Heurteaux, C.3
  • 9
    • 0036828345 scopus 로고    scopus 로고
    • Systemic fatty acid responses to transient focal cerebral ischemia: Influence of neuroprotectant therapy with human albumin
    • Rodriguez de Turco EB, Belayev L, Liu Y, et al. Systemic fatty acid responses to transient focal cerebral ischemia: influence of neuroprotectant therapy with human albumin. J Neurochem 2002; 83:515-524.
    • (2002) J Neurochem , vol.83 , pp. 515-524
    • Rodriguez de Turco, E.B.1    Belayev, L.2    Liu, Y.3
  • 10
    • 0021712166 scopus 로고
    • Docosahexaenoic acid (22:6, n-3) is metabolized to lipoxygenase reaction products in the retina
    • Bazan NG, Birkle DL, Reddy TS. Docosahexaenoic acid (22:6, n-3) is metabolized to lipoxygenase reaction products in the retina. Biochem Biophys Res Commun 1984; 125:741-747.
    • (1984) Biochem Biophys Res Commun , vol.125 , pp. 741-747
    • Bazan, N.G.1    Birkle, D.L.2    Reddy, T.S.3
  • 11
    • 0033606040 scopus 로고    scopus 로고
    • Kinetics of polymorphonuclear neutrophil infiltration after a traumatic brain injury in rat
    • Royo NC, Wahl F, Stutzmann JM. Kinetics of polymorphonuclear neutrophil infiltration after a traumatic brain injury in rat. Neuroreport 1999; 10:1363-1367.
    • (1999) Neuroreport , vol.10 , pp. 1363-1367
    • Royo, N.C.1    Wahl, F.2    Stutzmann, J.M.3
  • 12
    • 0029972079 scopus 로고    scopus 로고
    • Antibodies against adhesion molecules reduce apoptosis after transient middle cerebral artery occlusion in rat brain
    • Chopp M, Li Y, Zhang RL, et al. Antibodies against adhesion molecules reduce apoptosis after transient middle cerebral artery occlusion in rat brain. J Cereb Blood Flow Metab 1996; 16:578-584.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 578-584
    • Chopp, M.1    Li, Y.2    Zhang, R.L.3
  • 13
    • 0033933546 scopus 로고    scopus 로고
    • Contribution of microglia/macrophages to expansion of infarction and response of oligodendrocytes after focal cerebral ischemia in rats
    • Mabuchi T, Kitagawa K, Ohtsuki T, et al. Contribution of microglia/macrophages to expansion of infarction and response of oligodendrocytes after focal cerebral ischemia in rats. Stroke 2000; 31:1735-1743.
    • (2000) Stroke , vol.31 , pp. 1735-1743
    • Mabuchi, T.1    Kitagawa, K.2    Ohtsuki, T.3
  • 14
    • 0242290167 scopus 로고    scopus 로고
    • Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression
    • Marcheselli VL, Hong S, Lukiw WJ, et al. Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression. J Biol Chem 2003; 278:43807-43817.
    • (2003) J Biol Chem , vol.278 , pp. 43807-43817
    • Marcheselli, V.L.1    Hong, S.2    Lukiw, W.J.3
  • 15
    • 0034675852 scopus 로고    scopus 로고
    • Novel functional sets of lipid-derived mediators with anti-inflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal anti-inflammatory drugs and transcellular processing
    • Serhan CN, Clish CB, Brannon J, et al. Novel functional sets of lipid-derived mediators with anti-inflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal anti-inflammatory drugs and transcellular processing. J Exp Med 2000; 192:1197-1204.
    • (2000) J Exp Med , vol.192 , pp. 1197-1204
    • Serhan, C.N.1    Clish, C.B.2    Brannon, J.3
  • 16
    • 0037152160 scopus 로고    scopus 로고
    • Resolvins: A family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals
    • Serhan CN, Hong S, Gronert K, et al. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J Exp Med 2002; 196:1025-1037.
    • (2002) J Exp Med , vol.196 , pp. 1025-1037
    • Serhan, C.N.1    Hong, S.2    Gronert, K.3
  • 17
    • 0032586942 scopus 로고    scopus 로고
    • F4-isoprostanes as specific marker of docosahexaenoic acid peroxidation in Alzheimer's disease
    • Nourooz-Zadeh J, Liu EH, Yhlen B, et al. F4-isoprostanes as specific marker of docosahexaenoic acid peroxidation in Alzheimer's disease. J Neurochem 1999; 72:734-740.
    • (1999) J Neurochem , vol.72 , pp. 734-740
    • Nourooz-Zadeh, J.1    Liu, E.H.2    Yhlen, B.3
  • 18
    • 0031826073 scopus 로고    scopus 로고
    • Strong nuclear factor-kappaB-DNA binding parallels cyclooxygenase-2 gene transcription in aging and in sporadic Alzheimer's disease superior temporal lobe neocortex
    • Lukiw WJ, Bazan NG. Strong nuclear factor-kappaB-DNA binding parallels cyclooxygenase-2 gene transcription in aging and in sporadic Alzheimer's disease superior temporal lobe neocortex. J Neurosci Res 1998; 53:583-592.
    • (1998) J Neurosci Res , vol.53 , pp. 583-592
    • Lukiw, W.J.1    Bazan, N.G.2
  • 19
    • 0037119456 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and presenilin-1 gene expression induced by interleukin-1beta and amyloid beta 42 peptide is potentiated by hypoxia in primary human neural cells
    • Bazan NG, Lukiw WJ. Cyclooxygenase-2 and presenilin-1 gene expression induced by interleukin-1beta and amyloid beta 42 peptide is potentiated by hypoxia in primary human neural cells. J Biol Chem 2002; 277:30359-30367.
    • (2002) J Biol Chem , vol.277 , pp. 30359-30367
    • Bazan, N.G.1    Lukiw, W.J.2
  • 20
    • 0035227685 scopus 로고    scopus 로고
    • Amyloid-beta peptides are cytotoxic to oligodendrocytes
    • Xu J, Chen S, Ahmed SH, et al. Amyloid-beta peptides are cytotoxic to oligodendrocytes. J Neurosci 2001; 21:RC118.
    • (2001) J Neurosci , vol.21
    • Xu, J.1    Chen, S.2    Ahmed, S.H.3
  • 21
    • 17444412714 scopus 로고    scopus 로고
    • D1 (NPD1): A DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress [review]
    • Bazan NG. Neuroprotectin D1 (NPD1): a DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress [review]. Brain Pathol 2005; 15:159-166.
    • (2005) Brain Pathol , vol.15 , pp. 159-166
    • Neuroprotectin, B.N.G.1
  • 23
    • 0031942410 scopus 로고    scopus 로고
    • Regional membrane phospholipid alterations in Alzheimer's disease
    • Prasad MR, Lovell MA, Yatin M, et al. Regional membrane phospholipid alterations in Alzheimer's disease. Neurochem Res 1998; 23:81-88.
    • (1998) Neurochem Res , vol.23 , pp. 81-88
    • Prasad, M.R.1    Lovell, M.A.2    Yatin, M.3
  • 24
    • 0036710931 scopus 로고    scopus 로고
    • Lipid peroxidation in aging brain and Alzheimer's disease
    • Montine TJ, Neely MD, Quinn JF, et al. Lipid peroxidation in aging brain and Alzheimer's disease. Free Radic Biol Med 2002; 33:620-626.
    • (2002) Free Radic Biol Med , vol.33 , pp. 620-626
    • Montine, T.J.1    Neely, M.D.2    Quinn, J.F.3
  • 25
    • 0000657628 scopus 로고    scopus 로고
    • Effect of the long-term feeding of dietary lipids on the learning ability, fatty acid composition of brain stem phospholipids and synaptic membrane fluidity in adult mice: A comparison of sardine oil diet with palm oil diet
    • Suzuki H, Park SJ, Tamura M, et al. Effect of the long-term feeding of dietary lipids on the learning ability, fatty acid composition of brain stem phospholipids and synaptic membrane fluidity in adult mice: a comparison of sardine oil diet with palm oil diet. Mech Ageing Dev 1998; 101:119-128.
    • (1998) Mech Ageing Dev , vol.101 , pp. 119-128
    • Suzuki, H.1    Park, S.J.2    Tamura, M.3
  • 26
    • 0033067503 scopus 로고    scopus 로고
    • Low serum docosahexaenoic acid is a significant risk factor for Alzheimer's dementia
    • Kyle DJ, Schaefer E, Patton G, et al. Low serum docosahexaenoic acid is a significant risk factor for Alzheimer's dementia. Lipids 1999; 34 (Suppl):S245.
    • (1999) Lipids , vol.34 , Issue.SUPPL.
    • Kyle, D.J.1    Schaefer, E.2    Patton, G.3
  • 27
    • 0035089248 scopus 로고    scopus 로고
    • Chronic administration of docosahexaenoic acid improves the performance of radial arm maze task in aged rats
    • Gamoh S, Hashimoto M, Hossain S, et al. Chronic administration of docosahexaenoic acid improves the performance of radial arm maze task in aged rats. Clin Exp Pharmacol Physiol 2001; 28:266-270.
    • (2001) Clin Exp Pharmacol Physiol , vol.28 , pp. 266-270
    • Gamoh, S.1    Hashimoto, M.2    Hossain, S.3
  • 28
    • 0034759727 scopus 로고    scopus 로고
    • Reversibility of n-3 fatty acid deficiency-induced alterations of learning behavior in the rat: Level of n-6 fatty acids as another critical factor
    • Ikemoto A, Ohishi M, Sato Y, et al. Reversibility of n-3 fatty acid deficiency-induced alterations of learning behavior in the rat: level of n-6 fatty acids as another critical factor. J Lipid Res 2001; 42:1655-1663.
    • (2001) J Lipid Res , vol.42 , pp. 1655-1663
    • Ikemoto, A.1    Ohishi, M.2    Sato, Y.3
  • 29
    • 0036895833 scopus 로고    scopus 로고
    • Cognitive deficits in docosahexaenoic acid-deficient rats
    • Catalan J, Moriguchi T, Slotnick B, et al. Cognitive deficits in docosahexaenoic acid-deficient rats. Behav Neurosci 2002; 116:1022-1031.
    • (2002) Behav Neurosci , vol.116 , pp. 1022-1031
    • Catalan, J.1    Moriguchi, T.2    Slotnick, B.3
  • 30
    • 0030775948 scopus 로고    scopus 로고
    • Dietary fat intake and the risk of incident dementia in the Rotterdam study
    • Kalmijn S, Launer LJ, Ott A, et al. Dietary fat intake and the risk of incident dementia in the Rotterdam study. Ann Neurol 1997; 42:776-782.
    • (1997) Ann Neurol , vol.42 , pp. 776-782
    • Kalmijn, S.1    Launer, L.J.2    Ott, A.3
  • 31
    • 0037180207 scopus 로고    scopus 로고
    • Fish, meat, and risk of dementia: Cohort study
    • Barberger-Gateau P, Letenneur L, Deschamps V, et al. Fish, meat, and risk of dementia: cohort study. BMJ 2002; 325:932-933.
    • (2002) BMJ , vol.325 , pp. 932-933
    • Barberger-Gateau, P.1    Letenneur, L.2    Deschamps, V.3
  • 32
    • 0036592523 scopus 로고    scopus 로고
    • The significance of environmental factors in the etiology of Alzheimer's disease
    • Grant WB, Campbell A, Itzhaki RF, et al. The significance of environmental factors in the etiology of Alzheimer's disease. J Alzheimers Dis 2002; 4:179-189.
    • (2002) J Alzheimers Dis , vol.4 , pp. 179-189
    • Grant, W.B.1    Campbell, A.2    Itzhaki, R.F.3
  • 33
    • 0036165930 scopus 로고    scopus 로고
    • Prevalence of dementia in the older Japanese-Brazilian population
    • Yamada T, Kadekaru H, Matsumoto S, et al. Prevalence of dementia in the older Japanese-Brazilian population. Psychiatry Clin Neurosci 2002; 56:71-75.
    • (2002) Psychiatry Clin Neurosci , vol.56 , pp. 71-75
    • Yamada, T.1    Kadekaru, H.2    Matsumoto, S.3
  • 34
    • 0038115068 scopus 로고    scopus 로고
    • Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease
    • Morris MC, Evans DA, Bienias JL, et al. Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch Neurol 2003; 60:940-946.
    • (2003) Arch Neurol , vol.60 , pp. 940-946
    • Morris, M.C.1    Evans, D.A.2    Bienias, J.L.3
  • 35
    • 16244416174 scopus 로고    scopus 로고
    • A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model
    • Demonstration that diets enriched in DHA attenuate amyloid deposition in a neurodegeneration mouse model
    • Lim GP, Calon F, Morihara T, et al. A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model. J Neurosci 2005; 25:3032-3040. Demonstration that diets enriched in DHA attenuate amyloid deposition in a neurodegeneration mouse model.
    • (2005) J Neurosci , vol.25 , pp. 3032-3040
    • Lim, G.P.1    Calon, F.2    Morihara, T.3
  • 36
    • 0032524319 scopus 로고    scopus 로고
    • Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NFkappaB and stabilization of calcium homeostasis
    • Guo Q, Robinson N, Mattson MP. Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NFkappaB and stabilization of calcium homeostasis. J Biol Chem 1998; 273:12341-12351.
    • (1998) J Biol Chem , vol.273 , pp. 12341-12351
    • Guo, Q.1    Robinson, N.2    Mattson, M.P.3
  • 37
    • 0041355557 scopus 로고    scopus 로고
    • Notch and Presenilin: Regulated intramembrane proteolysis links development and degeneration
    • Selkoe D, Kopan R. Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration. Annu Rev Neurosci 2003; 26:565-597.
    • (2003) Annu Rev Neurosci , vol.26 , pp. 565-597
    • Selkoe, D.1    Kopan, R.2
  • 38
    • 0345600140 scopus 로고    scopus 로고
    • Interleukin-1 and nitric oxide increase NADPH oxidase activity in human coronary artery smooth muscle cells
    • Kaur J, Dhaunsi GS, Turner RB. Interleukin-1 and nitric oxide increase NADPH oxidase activity in human coronary artery smooth muscle cells. Med Princ Pract 2004; 13:26-29.
    • (2004) Med Princ Pract , vol.13 , pp. 26-29
    • Kaur, J.1    Dhaunsi, G.S.2    Turner, R.B.3
  • 39
    • 0037017399 scopus 로고    scopus 로고
    • Selective cytotoxicity of intracellular amyloid beta peptide1-42 through p53 and Bax in cultured primary human neurons
    • Zhang Y, McLaughlin R, Goodyer C, et al. Selective cytotoxicity of intracellular amyloid beta peptide1-42 through p53 and Bax in cultured primary human neurons. J Cell Biol 2002; 156:519-529.
    • (2002) J Cell Biol , vol.156 , pp. 519-529
    • Zhang, Y.1    McLaughlin, R.2    Goodyer, C.3
  • 40
    • 0037010289 scopus 로고    scopus 로고
    • Gene expression profiling of 12 633 genes in Alzheimer hippocampal CA1: Transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling
    • Colangelo V, Schurr J, Ball MJ, et al. Gene expression profiling of 12 633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling. J Neurosci Res 2002; 70:462-473.
    • (2002) J Neurosci Res , vol.70 , pp. 462-473
    • Colangelo, V.1    Schurr, J.2    Ball, M.J.3
  • 41
    • 10344238086 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha, interleukin-1beta, and interferon-gamma stimulate gamma-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway
    • Liao YF, Wang BJ, Cheng HT, et al. Tumor necrosis factor-alpha, interleukin-1beta, and interferon-gamma stimulate gamma-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway. J Biol Chem 2004; 279:49523-49532.
    • (2004) J Biol Chem , vol.279 , pp. 49523-49532
    • Liao, Y.F.1    Wang, B.J.2    Cheng, H.T.3
  • 42
    • 1442359840 scopus 로고    scopus 로고
    • Bcl-2 family regulation of neuronal development and neurodegeneration
    • Akhtar RS, Ness JM, Roth KA. Bcl-2 family regulation of neuronal development and neurodegeneration. Biochim Biophys Acta 2004; 1644:189-203.
    • (2004) Biochim Biophys Acta , vol.1644 , pp. 189-203
    • Akhtar, R.S.1    Ness, J.M.2    Roth, K.A.3
  • 43
    • 26444598506 scopus 로고    scopus 로고
    • Lukiw WJ, Cui JG, Marcheselli VL, et al. A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. J Clin Invest 2005; 115:2774-2783. Demonstration of NPD1 in human brain. Finding that NPD1 content is decreased in CA1 area of hippocampus. In human brain cells in culture, this study demonstrates that NPD1 induces a antiapoptotic, anti-inflammatory cell survival program by modifying gene expression.
    • Lukiw WJ, Cui JG, Marcheselli VL, et al. A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. J Clin Invest 2005; 115:2774-2783. Demonstration of NPD1 in human brain. Finding that NPD1 content is decreased in CA1 area of hippocampus. In human brain cells in culture, this study demonstrates that NPD1 induces a antiapoptotic, anti-inflammatory cell survival program by modifying gene expression.
  • 44
    • 1842428466 scopus 로고    scopus 로고
    • Expression of 11 members of the BCL-2 family of apoptosis regulatory molecules during human preimplantation embryo development and fragmentation
    • Metcalfe AD, Hunter HR, Bloor DJ, et al. Expression of 11 members of the BCL-2 family of apoptosis regulatory molecules during human preimplantation embryo development and fragmentation. Mol Reprod Dev 2004; 68:35-50.
    • (2004) Mol Reprod Dev , vol.68 , pp. 35-50
    • Metcalfe, A.D.1    Hunter, H.R.2    Bloor, D.J.3
  • 45
    • 2442617195 scopus 로고    scopus 로고
    • The Bcl-2 family member Bfl-1/A1 is strongly repressed in normal and malignant plasma cells but is a potent antiapoptotic factor for myeloma cells
    • Tarte K, Jourdan M, Veyrune JL, et al. The Bcl-2 family member Bfl-1/A1 is strongly repressed in normal and malignant plasma cells but is a potent antiapoptotic factor for myeloma cells. Br J Haematol 2004; 125:373-382.
    • (2004) Br J Haematol , vol.125 , pp. 373-382
    • Tarte, K.1    Jourdan, M.2    Veyrune, J.L.3
  • 46
    • 0032551528 scopus 로고    scopus 로고
    • Amyloid beta protein is internalized selectively by hippocampal field CA1 and causes neurons to accumulate amyloidogenic carboxyterminal fragments of the amyloid precursor protein
    • Bahr BA, Hoffman KB, Yang AJ, et al. Amyloid beta protein is internalized selectively by hippocampal field CA1 and causes neurons to accumulate amyloidogenic carboxyterminal fragments of the amyloid precursor protein. J Comp Neurol 1998; 397:139-147.
    • (1998) J Comp Neurol , vol.397 , pp. 139-147
    • Bahr, B.A.1    Hoffman, K.B.2    Yang, A.J.3
  • 47
    • 0037271080 scopus 로고    scopus 로고
    • Selective neuronal degeneration induced by soluble oligomeric amyloid beta protein
    • Kim HJ, Chae SC, Lee DK, et al. Selective neuronal degeneration induced by soluble oligomeric amyloid beta protein. FASEB J 2003; 17:118-120.
    • (2003) FASEB J , vol.17 , pp. 118-120
    • Kim, H.J.1    Chae, S.C.2    Lee, D.K.3
  • 48
    • 0141505027 scopus 로고    scopus 로고
    • Neocortical glial cell numbers in Alzheimer's disease: A stereological study
    • Pelvig DP, Pakkenberg H, Regeur L, et al. Neocortical glial cell numbers in Alzheimer's disease: a stereological study. Dement Geriatr Cogn Disord 2003; 16:212-219.
    • (2003) Dement Geriatr Cogn Disord , vol.16 , pp. 212-219
    • Pelvig, D.P.1    Pakkenberg, H.2    Regeur, L.3
  • 49
    • 12844271615 scopus 로고    scopus 로고
    • Correlation between astrocyte apoptosis and Alzheimer changes in gray matter lesions in Alzheimer's disease
    • Kobayashi K, Hayashi M, Nakano H, et al. Correlation between astrocyte apoptosis and Alzheimer changes in gray matter lesions in Alzheimer's disease. J Alzheimers Dis 2004; 6:623-632.
    • (2004) J Alzheimers Dis , vol.6 , pp. 623-632
    • Kobayashi, K.1    Hayashi, M.2    Nakano, H.3
  • 50
    • 2442707942 scopus 로고    scopus 로고
    • Astrocyte modulation of in vitro beta-amyloid neurotoxicity
    • Paradisi S, Sacchetti B, Balduzzi M, et al. Astrocyte modulation of in vitro beta-amyloid neurotoxicity. Glia 2004; 46:252-260.
    • (2004) Glia , vol.46 , pp. 252-260
    • Paradisi, S.1    Sacchetti, B.2    Balduzzi, M.3
  • 51
    • 0032967259 scopus 로고    scopus 로고
    • Apoptotic cell death in neurons and glial cells: Implications for Alzheimer's disease
    • Kitamura Y, Taniguchi T, Shimohama S. Apoptotic cell death in neurons and glial cells: implications for Alzheimer's disease. Jpn J Pharmacol 1999; 79:1-5.
    • (1999) Jpn J Pharmacol , vol.79 , pp. 1-5
    • Kitamura, Y.1    Taniguchi, T.2    Shimohama, S.3
  • 52
    • 4444223956 scopus 로고    scopus 로고
    • Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model
    • Calon F, Lim GP, Yang F, et al. Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model. Neuron 2004; 43:633-645.
    • (2004) Neuron , vol.43 , pp. 633-645
    • Calon, F.1    Lim, G.P.2    Yang, F.3
  • 53
    • 14944376646 scopus 로고    scopus 로고
    • Chronic administration of docosahexaenoic acid ameliorates the impairment of spatial cognition learning ability in amyloid (beta)-infused rats
    • Hashimoto M, Tanabe Y, Fujii Y, et al. Chronic administration of docosahexaenoic acid ameliorates the impairment of spatial cognition learning ability in amyloid (beta)-infused rats. J Nutr 2005; 135:549-555.
    • (2005) J Nutr , vol.135 , pp. 549-555
    • Hashimoto, M.1    Tanabe, Y.2    Fujii, Y.3
  • 54
    • 2942625603 scopus 로고    scopus 로고
    • Neuroprotectin D1: A docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress
    • Mukherjee PK, Marcheselli VL, Serhan CN, et al. Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress. Proc Natl Acad Sci U S A 2004; 101:8491-8496.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8491-8496
    • Mukherjee, P.K.1    Marcheselli, V.L.2    Serhan, C.N.3
  • 55
    • 0037767814 scopus 로고    scopus 로고
    • Interferon gamma stimulates beta-secretase expression and sAPPbeta production in astrocytes
    • Hong HS, Hwang EM, Sim HJ, et al. Interferon gamma stimulates beta-secretase expression and sAPPbeta production in astrocytes. Biochem Biophys Res Commun 2003; 307:922-927.
    • (2003) Biochem Biophys Res Commun , vol.307 , pp. 922-927
    • Hong, H.S.1    Hwang, E.M.2    Sim, H.J.3
  • 56
    • 0038705106 scopus 로고    scopus 로고
    • Role of cytokines in the gene expression of amyloid beta-protein precursor: Identification of a 5′-UTR-binding nuclear factor and its implications in Alzheimer's disease
    • Lahiri DK, Chen D, Vivien D, et al. Role of cytokines in the gene expression of amyloid beta-protein precursor: identification of a 5′-UTR-binding nuclear factor and its implications in Alzheimer's disease. J Alzheimers Dis 2003; 5:81-90.
    • (2003) J Alzheimers Dis , vol.5 , pp. 81-90
    • Lahiri, D.K.1    Chen, D.2    Vivien, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.