mTOR dysfunction contributes to vacuolar pathology and weakness in valosin-containing protein associated inclusion body myopathy

Human Molecular Genetics

Volumn 22, Issue 6, 2013, Pages 1167-1179

  Ching, James K ^a   Elizabeth, Sarita V ^a   Ju, Jeong Sun ^a   Lusk, Caleb ^a   Pittman, Sara K ^a   Weihl, Conrad C ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ATROGIN 1; CREATINE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MUSCLE RING FINGER 1 PROTEIN; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHRL1; UBIQUITINATED PROTEIN; VALOSIN CONTAINING PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL INCLUSION; CELL VACUOLE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; INCLUSION BODY MYOPATHY; MOUSE; MUSCLE STRENGTH; MUSCLE WEAKNESS; MYOPATHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATASES; ANIMALS; AUTOPHAGY; CELL CYCLE PROTEINS; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOSITIS, INCLUSION BODY; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; VACUOLES;

EID: 84874529071     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/dds524     Document Type: Article

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