Macrophage-targeted delivery systems for nucleic acid therapy of inflammatory diseases

Journal of Controlled Release

Volumn 190, Issue , 2014, Pages 515-530

  Singh, Amit ^a   Talekar, Meghna ^a   Raikar, Ankita ^a   Amiji, Mansoor ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Inflammatory diseases; Macrophage targeting; Nanoparticles; Nucleic acid therapy

Indexed keywords

BIOMOLECULES; DISEASES; ENZYME ACTIVITY; IMMUNE SYSTEM; NANOPARTICLES; NUCLEIC ACIDS; PATHOLOGY; TISSUE; TISSUE HOMEOSTASIS; MACROPHAGES;

ANTI-INFLAMMATORIES; CHRONIC INFLAMMATORY DISEASE; FUNCTIONAL DIVERSITY; INFLAMMATORY DISEASE; INNATE IMMUNE SYSTEMS; MACROPHAGE TARGETING; MOLECULAR TARGETS; PATHOPHYSIOLOGICAL; TARGETED DELIVERY SYSTEMS;

MACROPHAGES; DISEASE CONTROL;

ACETYLSALICYLIC ACID; CHEMOKINE; COLONY STIMULATING FACTOR 1; CYTOKINE; FOLATE RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 18; INTERLEUKIN 23; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; NUCLEIC ACID; ORGANIC CATION TRANSPORTER 3; SALICYLATE SODIUM; ANTIINFLAMMATORY AGENT; NANOPARTICLE; ANTISENSE OLIGONUCLEOTIDE; CELL ADHESION MOLECULE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 11; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 2; INTERLEUKIN 7; MACROPHAGE MIGRATION INHIBITION FACTOR; MESSENGER RNA; MICRORNA; MIGRATION INHIBITION FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; OSTEOPONTIN; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; VASCULAR CELL ADHESION MOLECULE 1;

ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CROHN DISEASE; DIABETES MELLITUS; GENE MUTATION; HUMAN; IMMUNE RESPONSE; IMMUNOGENICITY; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; MACROPHAGE; MEDIATOR; MICROENVIRONMENT; MOLECULARLY TARGETED THERAPY; NANOTECHNOLOGY; NEOPLASM; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PHENOTYPE; PRIORITY JOURNAL; REVIEW; RHEUMATOID ARTHRITIS; ULCERATIVE COLITIS; VIRUS VIRULENCE; DRUG DELIVERY SYSTEM; IMMUNOLOGY; AGING; CELL POPULATION; CHROMOSOME 16; CYTOKINE RELEASE; DENDRITIC CELL; HYPERGLYCEMIA; IMMUNITY; INFLAMMATORY BOWEL DISEASE; INFLAMMATORY DISEASE; INSULIN RELEASE; MICROSATELLITE MARKER; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEIC ACID THERAPY; OBESITY; OSTEOCLAST; PATHOGENESIS; PHYSICAL INACTIVITY;

ANTI-INFLAMMATORY AGENTS; DRUG DELIVERY SYSTEMS; HUMANS; INFLAMMATION; MACROPHAGES; NANOPARTICLES; NUCLEIC ACIDS;

EID: 84906781924     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.04.021     Document Type: Review

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