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Volumn 12, Issue 11, 2007, Pages 4298-4314

Macrophages and the hypoxic tumour microenvironment

Author keywords

Angiogenesis; Hypoxia; Immunosuppression; Metastasis; Migration; Review; TAM; Therapy; Tumour associated macrophage

Indexed keywords

ANTINEOPLASTIC AGENT;

EID: 34347231274     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/2389     Document Type: Article
Times cited : (65)

References (170)
  • 1
    • 0023836831 scopus 로고
    • Macrophages in human breast disease: A quantitative immunohistochemical study
    • Kelly P. M., R. S. Davison, E. Bliss & J. O. McGee: Macrophages in human breast disease: a quantitative immunohistochemical study. Br J Cancer 57, 174-177 (1988) (Pubitemid 18085399)
    • (1988) British Journal of Cancer , vol.57 , Issue.2 , pp. 174-177
    • Kelly, P.M.A.1    Davison, R.S.2    Bliss, E.3    McGee, O.D.J.4
  • 2
    • 0028080215 scopus 로고
    • Cytokine networks in solid human tumors: Regulation of angiogenesis
    • Leek R. D., A. L. Harris & C. E. Lewis: Cytokine networks in solid human tumors: regulation of angiogenesis. J Leukoc Biol 56, 423-435 (1994) (Pubitemid 24319901)
    • (1994) Journal of Leukocyte Biology , vol.56 , Issue.4 , pp. 423-435
    • Leek, R.D.1    Harris, A.L.2    Lewis, C.E.3
  • 3
    • 0032700286 scopus 로고    scopus 로고
    • Tumor cytotoxicity of peritoneal macrophages and peripheral blood monocytes from patients with ovarian, endometrial, and cervical cancer
    • Wilbanks G. D., M. C. Ahn, D. A. Beck & D. P. Braun: Tumor cytotoxicity of peritoneal macrophages and peripheral blood monocytes from patients with ovarian, endometrial, and cervical cancer. Int J Gynecol Cancer 9, 427-432 (1999)
    • (1999) Int J Gynecol Cancer , vol.9 , pp. 427-432
    • Wilbanks, G.D.1    Ahn, M.C.2    Beck, D.A.3    Braun, D.P.4
  • 4
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
    • DOI 10.1002/path.1027
    • Bingle L., N. J. Brown & C. E. Lewis: The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J Pathol 196, 254-265 (2002) (Pubitemid 34189413)
    • (2002) Journal of Pathology , vol.196 , Issue.3 , pp. 254-265
    • Bingle, L.1    Brown, N.J.2    Lewis, C.E.3
  • 5
    • 33645991795 scopus 로고    scopus 로고
    • Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
    • Sica A., T. Schioppa, A. Mantovani & P. Allavena: Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur J Cancer 42, 717-727 (2006)
    • (2006) Eur J Cancer , vol.42 , pp. 717-727
    • Sica, A.1    Schioppa, T.2    Mantovani, A.3    Allavena, P.4
  • 6
    • 0021281497 scopus 로고
    • A high macrophage content in human breast cancer is not associated with favourable prognostic factors
    • Steele R. J., O. Eremin, M. Brown & R. A. Hawkins: A high macrophage content in human breast cancer is not associated with favourable prognostic factors. Br J Surg 71, 456-458 (1984) (Pubitemid 14116573)
    • (1984) British Journal of Surgery , vol.71 , Issue.6 , pp. 456-458
    • Steele, R.J.C.1    Eremin, O.2    Brown, M.3    Hawkins, R.A.4
  • 7
    • 24744454660 scopus 로고    scopus 로고
    • Macrophage infiltration and its prognostic implications in breast cancer: The relationship with VEGF expression and microvessel density
    • Tsutsui S., K. Yasuda, K. Suzuki, K. Tahara, H. Higashi & S. Era: Macrophage infiltration and its prognostic implications in breast cancer: the relationship with VEGF expression and microvessel density. Oncol Rep 14, 425-431 (2005)
    • (2005) Oncol Rep , vol.14 , pp. 425-431
    • Tsutsui, S.1    Yasuda, K.2    Suzuki, K.3    Tahara, K.4    Higashi, H.5    Era, S.6
  • 8
    • 0029816609 scopus 로고    scopus 로고
    • Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
    • Leek R. D., C. E. Lewis, R. Whitehouse, M. Greenall, J. Clarke & A. L. Harris: Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res 56, 4625-4629 (1996) (Pubitemid 26338061)
    • (1996) Cancer Research , vol.56 , Issue.20 , pp. 4625-4629
    • Leek, R.D.1    Lewis, C.E.2    Whitehouse, R.3    Greenall, M.4    Clarke, J.5    Harris, A.L.6
  • 9
    • 0029598463 scopus 로고
    • Clinicopathologic analysis of macrophage infiltrates in breast carcinoma
    • Visscher D. W., P. Tabaczka, D. Long & J. D. Crissman: Clinicopathologic analysis of macrophage infiltrates in breast carcinoma. Pathol Res Pract 191, 1133-139 (1995) (Pubitemid 26031759)
    • (1995) Pathology Research and Practice , vol.191 , Issue.11 , pp. 1133-1139
    • Visscher, D.W.1    Tabaczka, P.2    Long, P.3    Crissman, J.D.4
  • 10
    • 0023179981 scopus 로고
    • In situ quantitation of inflammatory mononuclear cells in ductal infiltrating breast carcinoma: Relation of prognostic parameters
    • An T., U. Sood, T. Pietruk, G. Cummings, K. Hashimoto & J. D. Crissman: In situ quantitation of inflammatory mononuclear cells in ductal infiltrating carcinoma. Relation to prognostic parameters. Am J Pathol 128, 52-60 (1987) (Pubitemid 17094335)
    • (1987) American Journal of Pathology , vol.128 , Issue.1 , pp. 52-60
    • An, T.1    Sood, U.2    Pietruk, T.3
  • 11
    • 0033938697 scopus 로고    scopus 로고
    • Prognostic value of tumor-associated macrophage count in human bladder cancer
    • DOI 10.1046/j.1442-2042.2000.00190.x
    • Hanada T., M. Nakagawa, A. Emoto, T. Nomura, N. Nasu & Y. Nomura: Prognostic value of tumour-associated macrophage count in human bladder cancer. Int J Urol 7, 263-269 (2000) (Pubitemid 30440592)
    • (2000) International Journal of Urology , vol.7 , Issue.7 , pp. 263-269
    • Hanada, T.1    Nakagawa, M.2    Emoto, A.3    Nomura, T.4    Nasu, N.5    Nomura, Y.6
  • 12
    • 0022437292 scopus 로고
    • TUMORASSOZIIERTES MONONUKLEARES ZELLINFILTRAT UND REZIDIVNEIGUNG BEIM OBERFLACHLICHEN UROTHELKARZINOM DER HARNBLASE
    • Flamm J. & A. Benesch: Tumor-associated mononuclear cell infiltrate and recurrence rate in the superficial urothelial carcinoma of the urinary bladder. Urol Int 41, 187-191 (1986) (Pubitemid 16040877)
    • (1986) Urologia Internationalis , vol.41 , Issue.3 , pp. 187-191
    • Flamm, J.1    Benesch, A.2
  • 13
    • 4544336555 scopus 로고    scopus 로고
    • Significance of macrophage chemoattractant protein-1 expression and macrophage infiltration in squamous cell carcinoma of the esophagus
    • DOI 10.1111/j.1572-0241.2004.30733.x
    • Koide N., A. Nishio, T. Sato, A. Sugiyama & S. Miyagawa: Significance of macrophage chemoattractant protein-1 expression and macrophage infiltration in squamous cell carcinoma of the esophagus. Am J Gastroenterol 99, 1667-1674 (2004) (Pubitemid 39237489)
    • (2004) American Journal of Gastroenterology , vol.99 , Issue.9 , pp. 1667-1674
    • Koide, N.1    Nishio, A.2    Sato, T.3    Sugiyama, A.4    Miyagawa, S.-I.5
  • 14
    • 0032953480 scopus 로고    scopus 로고
    • Interrelations of clinicopathological variables, local immune response and prognosis in esophageal squamous cell carcinoma
    • Ma Y., M. Xian, J. Li, T. Kawabata & S. Okada: Interrelations of clinicopathological variables, local immune response and prognosis in esophageal squamous cell carcinoma. APMIS 107, 514-522 (1999) (Pubitemid 29202908)
    • (1999) APMIS , vol.107 , Issue.5 , pp. 514-522
    • Ma, Y.1    Xian, M.2    Li, J.3    Kawabata, T.4    Okada, S.5
  • 17
    • 0032867830 scopus 로고    scopus 로고
    • Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: Association with angiogenesis and poor prognosis
    • DOI 10.1159/000012021
    • Takanami I., K. Takeuchi & S. Kodaira: Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: association with angiogenesis and poor prognosis. Oncology 57, 138-142 (1999) (Pubitemid 29385492)
    • (1999) Oncology , vol.57 , Issue.2 , pp. 138-142
    • Takanami, I.1    Takeuchi, K.2    Kodaira, S.3
  • 18
    • 0346671183 scopus 로고    scopus 로고
    • Association of macrophages, mast cells and eosinophil leukocytes with angiogenesis and tumor stage in non-small cell lung carcinomas (NSCLC)
    • DOI 10.1016/j.lungcan.2003.08.013
    • Tataroglu C., A. Kargi, S. Ozkal, N. Esrefoglu & A. Akkoclu: Association of macrophages, mast cells and eosinophil leukoytes with angiogenesis and tumor stage in non-small cell lung carcinomas (NSCLC). Lung Cancer 43, 47-54 (2004) (Pubitemid 38096291)
    • (2004) Lung Cancer , vol.43 , Issue.1 , pp. 47-54
    • Tataroglu, C.1    Kargi, A.2    Ozkal, S.3    Esrefoglu, N.4    Akkoclu, A.5
  • 19
    • 32644466544 scopus 로고    scopus 로고
    • Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer
    • DOI 10.1200/JCO.2005.01.4910
    • Welsh T. J., R. H. Green, D. Richardson, D. A. Waller, K. J. O'Byrne & P. Bradding: Macrophage and mast-cell invasion of tumour islets confers a marked survival advantage in non-small-cell lung cancer. J Clin Oncol 23, 8959-8967 (2005) (Pubitemid 46211481)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.35 , pp. 8959-8967
    • Welsh, T.J.1    Green, R.H.2    Richardson, D.3    Waller, D.A.4    O'Byrne, K.J.5    Bradding, P.6
  • 21
    • 14844361270 scopus 로고    scopus 로고
    • Prognostic significance of cell infiltrations of immunosurveillance in colorectal cancer
    • Tan S. Y., Y. Fan, H. S. Luo, Z. X. Shen, Y. Guo & L. J. Zhao: Prognostic significance of cell infiltrations of immunosurveillance in colorectal cancer. World J Gastroenterol 11, 1210-1214 (2005) (Pubitemid 40353010)
    • (2005) World Journal of Gastroenterology , vol.11 , Issue.8 , pp. 1210-1214
    • Tan, S.-Y.1    Fan, Y.2    Luo, H.-S.3    Shen, Z.-X.4    Guo, Y.5    Zhao, L.-J.6
  • 22
    • 0038148426 scopus 로고    scopus 로고
    • Prognostic significance of CD8+ T cell and macrophage peritumoural infiltration in colorectal cancer
    • Funada Y., T. Noguchi, R. Kikuchi, S. Takeno, Y. Uchida & H. E. Gabbert: Prognostic significance of CD8+ T cell and macrophage peritumoural infiltration in colorectal cancer. Oncol Rep 19, 309-313 (2003)
    • (2003) Oncol Rep , vol.19 , pp. 309-313
    • Funada, Y.1    Noguchi, T.2    Kikuchi, R.3    Takeno, S.4    Uchida, Y.5    Gabbert, H.E.6
  • 23
    • 0034266661 scopus 로고    scopus 로고
    • Tumour associated macrophages in human prostate cancer: Relation to clinicopathological variables and survival
    • Lissbrant I. F., P. Stattin, P. Wikstrom, J. E. Damber, L. Egevad & A. Bergh: Tumour associated macrophages in human prostate cancer: relation to clinicopathological variables and survival. Int J Oncol 17, 445-451 (2000)
    • (2000) Int J Oncol , vol.17 , pp. 445-451
    • Lissbrant, I.F.1    Stattin, P.2    Wikstrom, P.3    Damber, J.E.4    Egevad, L.5    Bergh, A.6
  • 24
    • 24744438473 scopus 로고    scopus 로고
    • Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma (FL)
    • DOI 10.1182/blood-2005-04-1565
    • Farinha P., H. Masoudi, B. F. Skinnider, K. Shumansky, J. J. Spinelli, K. Gill, R. Klasa, N. Voss, J. M. Connors & R. D. Gascoyne: Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma (FL). Blood 106, 2169-2174 (2005) (Pubitemid 41291735)
    • (2005) Blood , vol.106 , Issue.6 , pp. 2169-2174
    • Farinha, P.1    Masoudi, H.2    Skinnider, B.F.3    Shumansky, K.4    Spinelli, J.J.5    Gill, K.6    Klasa, R.7    Voss, N.8    Connors, J.M.9    Gascoyne, R.D.10
  • 27
    • 10744224063 scopus 로고    scopus 로고
    • The Degree of Macrophage Infiltration into the Cancer Cell Nest is a Significant Predictor of Survival in Gastric Cancer Patients
    • Ohno S., H. Inagawa, D. K. Dhar, T. Fujii, S. Ueda, M. Tachibana, N. Suzuki, M. Inoue, G. Soma & N. Nagasue: The degree of macrophage infiltration into the cancer cell nest is a significant predictor of survival in gastric cancer patients. Anticancer Res 23, 5015-5022 (2003) (Pubitemid 38182119)
    • (2003) Anticancer Research , vol.23 , Issue.6 D , pp. 5015-5022
    • Ohno, S.1    Inagawa, H.2    Dhar, D.K.3    Fujii, T.4    Ueda, S.5    Tachibana, M.6    Suzuki, N.7    Inoue, M.8    Soma, G.-I.9    Nagasue, N.10
  • 28
    • 0029817660 scopus 로고    scopus 로고
    • Vascular cell adhesion molecule-1 is involved in mediating hypoxia- induced sickle red blood cell adherence to endothelium: Potential role in sickle cell disease
    • Setty B. N. & M. J. Stuart: Vascular cell adhesion molecule-1 is involved in mediating hypoxia-induced sickle red blood cell adherence to endothelium: potential role in sickle cell disease. Blood 88, 2311-2320 (1996) (Pubitemid 26307936)
    • (1996) Blood , vol.88 , Issue.6 , pp. 2311-2320
    • Setty, B.N.Y.1    Stuart, M.J.2
  • 31
    • 0035860845 scopus 로고    scopus 로고
    • Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1, and E-selectin expression
    • Kim I., S. O. Moon, S. K. Park, S. W. Chae & G. Y. Koh: Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1 and E-selectin expression. Circ Res 89, 477-479 (2001) (Pubitemid 34132640)
    • (2001) Circulation Research , vol.89 , Issue.6 , pp. 477-479
    • Kim, I.1    Moon, S.-O.2    Sung, K.P.3    Soo, W.C.4    Gou, Y.K.5
  • 32
    • 0242368135 scopus 로고    scopus 로고
    • Arrest chemokines
    • DOI 10.1038/sj.mn.7800194
    • Ley K.: Arrest chemokines. Microcirculation 10, 289-295 (2003) (Pubitemid 39004256)
    • (2003) Microcirculation , vol.10 , Issue.3-4 , pp. 289-295
    • Ley, K.1
  • 33
    • 0033568215 scopus 로고    scopus 로고
    • Elevated expression of the CC chemokine regulated on activation, normal T cell expressed and secreted (RANTES) in advanced breast carcinoma
    • Luboshits G., S. Shina, O. Kaplan, S. Engelberg, D. Nass, B. Lifshitz-Mercer, S. Chaitchik, I. Keydar & A. Ben-Baruch: Elevated expression of the CC chemokine regulated on activation, normal T cell expressed and secreted (RANTES) in advanced breast carcinoma. Cancer Res 59, 4681-4687 (1999) (Pubitemid 29428976)
    • (1999) Cancer Research , vol.59 , Issue.18 , pp. 4681-4687
    • Luboshits, G.1    Shina, S.2    Kaplan, O.3    Engelberg, S.4    Nass, D.5    Lifshitz-Mercer, B.6    Chaitchik, S.7    Keydar, I.8    Ben-Baruch, A.9
  • 34
    • 0035120421 scopus 로고    scopus 로고
    • Correlation of tissue and plasma RANTES levels with disease course in patients with breast or cervical cancer
    • Niwa Y., H. Akamatsu, H. Niwa, H. Sumi, Y. Ozaki & A. Abe: Correlation of tissue and plasma RANTES levels with disease course in patients with breast or cervical cancer. Clin Cancer Res 7, 285-289 (2001) (Pubitemid 32183031)
    • (2001) Clinical Cancer Research , vol.7 , Issue.2 , pp. 285-289
    • Niwa, Y.1    Akamatsu, H.2    Niwa, H.3    Sumi, H.4    Ozaki, Y.5    Abe, A.6
  • 36
    • 0026900407 scopus 로고
    • Characterisation of GRO alpha, beta and gamma expression in human colonic tumours: Potential significance of cytokine involvement
    • Cuenca R. E., R. G. Azizkhan & S. Hasgill: Characterisation of GRO alpha, beta and gamma expression in human colonic tumours: potential significance of cytokine involvement. Surg Oncol 1, 323-329 (1992)
    • (1992) Surg Oncol , vol.1 , pp. 323-329
    • Cuenca, R.E.1    Azizkhan, R.G.2    Hasgill, S.3
  • 37
    • 0033021558 scopus 로고    scopus 로고
    • The chemokine RANTES is secreted by human melanoma cells and is associated with enhanced tumour formation in nude mice
    • DOI 10.1038/sj.bjc.6690164
    • Mrowietz U., U. Schwenk, S. Maune, J. Bartels, M. Kupper, I. Fichtner, J. M. Schroder & D. Schadendorf: The chemokine RANTES is secreted by human melanoma cells and is associated with enhanced tumour formation in nude mice. Br J Cancer 79, 1025-1031 (1999) (Pubitemid 29087870)
    • (1999) British Journal of Cancer , vol.79 , Issue.7-8 , pp. 1025-1031
    • Mrowietz, U.1    Schwenk, U.2    Maune, S.3    Bartels, J.4    Kupper, M.5    Fichtner, I.6    Schroder, J.-M.7    Schadendorf, D.8
  • 39
    • 0033903714 scopus 로고    scopus 로고
    • Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer
    • Ueno T., M. Toi, H. Saji, M. Muta, H. Bando, K. Kuroi, M. Koike, H. Inadera & K. Matsushima: Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer. Clin Cancer Res 6, 3282-3289 (2000) (Pubitemid 30637758)
    • (2000) Clinical Cancer Research , vol.6 , Issue.8 , pp. 3282-3289
    • Ueno, T.1    Toi, M.2    Saji, H.3    Muta, M.4    Bando, H.5    Kuroi, K.6    Koike, M.7    Inadera, H.8    Matsushima, K.9
  • 42
    • 0035336409 scopus 로고    scopus 로고
    • Low-level monocyte chemoattractant protein-1 stimulation of monocytes leads to tumor formation in nontumorigenic melanoma cells
    • Nesbit M., H. Schaider, T. H. Miller & M. Herlyn: Low-level monocyte chemoattractant protein-1 stimulation of monocytes leads to tumour formation in nontumourigenic melanoma cells. J Immunol 166, 6483-6490 (2001) (Pubitemid 32467185)
    • (2001) Journal of Immunology , vol.166 , Issue.11 , pp. 6483-6490
    • Nesbit, M.1    Schaider, H.2    Miller, T.H.3    Herlyn, M.4
  • 43
    • 0029155911 scopus 로고
    • Monocyte chemoattractant protein-1 stimulates tumour necrosis and recruitment of macrophages into tumours in tumour-bearing nude mice: Increased granulocyte and macrophage progenitors in bone marrow
    • Hoshino Y., K. Hatake, T. Kasahara, Y. Takahashi, M. Ikeda, H. Tomizuka, T. Ohtsuki, M. Uwai, N. Mukaida & K. Matsushima: Monocyte chemoattractant protein-1 stimulates tumour necrosis and recruitment of macrophages into tumours in tumour-bearing nude mice: increased granulocyte and macrophage progenitors in bone marrow. Exp Hematol 23, 1035-1039 (1995)
    • (1995) Exp Hematol , vol.23 , pp. 1035-1039
    • Hoshino, Y.1    Hatake, K.2    Kasahara, T.3    Takahashi, Y.4    Ikeda, M.5    Tomizuka, H.6    Ohtsuki, T.7    Uwai, M.8    Mukaida, N.9    Matsushima, K.10
  • 44
    • 0036533579 scopus 로고    scopus 로고
    • Analysis of the gene expression profile activated by the CC chemokine ligand 5/RANTES and by lipopolysaccharide in human monocytes
    • Locati M., U. Deuschle, M. L. Massardi, F. O. Martinez, M. Sironi, S. Sozzani, T. Bartfai & A. Mantovani: Analysis of the gene expression profile activated by the CC chemokine ligand 5/RANTES and by lipopolysaccharide in human monocytes. J Immunol 168, 3557-3562 (2002) (Pubitemid 34250425)
    • (2002) Journal of Immunology , vol.168 , Issue.7 , pp. 3557-3562
    • Locati, M.1    Deuschle, U.2    Massardi, M.L.3    Martinez, F.O.4    Sironi, M.5    Sozzani, S.6    Bartfai, T.7    Mantovani, A.8
  • 45
    • 0036167093 scopus 로고    scopus 로고
    • CD99 plays a major role in the migration of monocytes through endothelial junctions
    • DOI 10.1038/ni749
    • Schenkel A. R., Z. Mamdouh, X. Chen, R. M. Liebman & W. A. Muller: CD99 plays a major role in the migration of monocytes through endothelial junctions. Nat Immunol 3, 143-150 (2002) (Pubitemid 34141444)
    • (2002) Nature Immunology , vol.3 , Issue.2 , pp. 143-150
    • Schenkel, A.R.1    Mamdouh, Z.2    Chen, X.3    Liebman, R.M.4    Muller, W.A.5
  • 46
    • 33750703246 scopus 로고    scopus 로고
    • Hypoxia induces PECAM-1 phosphorylation and transendothelial migration of monocytes
    • Kalra V. K., Y. Shen, C. Sultana & V. Rattan: Hypoxia induces PECAM-1 phosphorylation and transendothelial migration of monocytes. Am J Physiol 271, H2025-2034 (1996)
    • (1996) Am J Physiol , vol.271
    • Kalra, V.K.1    Shen, Y.2    Sultana, C.3    Rattan, V.4
  • 47
    • 33646030601 scopus 로고    scopus 로고
    • Altered expression of cellular membrane molecules of HLA-DR, HLA-G and CD99 in cervical intraepithelial neoplasias and invasive squamous cell carcinoma
    • Zhou J. H., F. Ye, H. Z. Chen, C. Y. Zhou, W. G. Lu & X. Xie: Altered expression of cellular membrane molecules of HLA-DR, HLA-G and CD99 in cervical intraepithelial neoplasias and invasive squamous cell carcinoma. Life Sci 78, 2643-2649 (2006)
    • (2006) Life Sci , vol.78 , pp. 2643-2649
    • Zhou, J.H.1    Ye, F.2    Chen, H.Z.3    Zhou, C.Y.4    Lu, W.G.5    Xie, X.6
  • 48
    • 0031710240 scopus 로고    scopus 로고
    • Androgen regulation of the human pseudoautosomal gene MIC2, a potential marker for prostate cancer
    • DOI 10.1002/(SICI)1098-2744(199809)23:1<13::AID-MC2>3.0.CO;2-I
    • Shen J., H. E. Zhau, S. D. Hursting & L. W. Chung: Androgen regulation of the human pseudoautosomal gene MIC2, a potential marker for prostate cancer. Mol Carcinog 23, 13-19 (1998) (Pubitemid 28441055)
    • (1998) Molecular Carcinogenesis , vol.23 , Issue.1 , pp. 13-19
    • Shen, J.1    Zhau, H.E.2    Hursting, S.D.3    Chung, L.W.K.4
  • 49
    • 0034649507 scopus 로고    scopus 로고
    • Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling
    • DOI 10.1038/sj.onc.1204012
    • Wykoff C. C., C. W. Pugh, P. H. Maxwell, A. L. Harris & Ratcliffe P. J: Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential display profiling. Oncogene 19, 6297-6305 (2000) (Pubitemid 32641843)
    • (2000) Oncogene , vol.19 , Issue.54 , pp. 6297-6305
    • Wykoff, C.C.1    Pugh, C.W.2    Maxwell, P.H.3    Harris, A.L.4    Ratcliffe, P.J.5
  • 50
    • 0030614893 scopus 로고    scopus 로고
    • 2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation
    • DOI 10.1038/nm0297-177
    • Helmlinger G., F. Yuan, M. Dellian & R. K. Jain: Interstitial pH and pO2 gradients in solid tumours in vivo: high resolution measurements reveal a lack of correlation. Nat Med 3, 177-182 (1997) (Pubitemid 27064702)
    • (1997) Nature Medicine , vol.3 , Issue.2 , pp. 177-182
    • Helmlinger, G.1    Yuan, F.2    Dellian, M.3    Jain, R.K.4
  • 51
    • 0029088440 scopus 로고
    • Patterns and variability of tumour oxygenation in human soft tissue sarcomas, cervical carcinomas and lymph node metastases
    • Brizel D. M., G. L. Rosner, L. R. Prosnitz & M. W. Dewhirst: Patterns and variability of tumour oxygenation in human soft tissue sarcomas, cervical carcinomas and lymph node metastases. Int J Radiat Oncol Biol Phys 32, 1121-1125 (1995)
    • (1995) Int J Radiat Oncol Biol Phys , vol.32 , pp. 1121-1125
    • Brizel, D.M.1    Rosner, G.L.2    Prosnitz, L.R.3    Dewhirst, M.W.4
  • 52
    • 4944244259 scopus 로고    scopus 로고
    • Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
    • DOI 10.1182/blood-2004-03-1109
    • Murdoch C., A. Giannoudis & C. E. Lewis: Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumours and other ischaemic tissues. Blood 104, 2224-2234 (2004) (Pubitemid 39331817)
    • (2004) Blood , vol.104 , Issue.8 , pp. 2224-2234
    • Murdoch, C.1    Giannoudis, A.2    Lewis, C.E.3
  • 53
    • 3042822267 scopus 로고    scopus 로고
    • Cancer and the chemokine network
    • Balkwill F.: Cancer and the chemokine network. Nat Rev Cancer 4, 540-550 (2004) (Pubitemid 38868623)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.7 , pp. 540-550
    • Balkwill, F.1
  • 54
    • 0029867554 scopus 로고    scopus 로고
    • Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
    • Barleon B., S. Sozzani, D. Zhou, H. A. Weich, A. Montavani & D. Marme: Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood 87, 3336-3343 (1996) (Pubitemid 26115364)
    • (1996) Blood , vol.87 , Issue.8 , pp. 3336-3343
    • Barleon, B.1    Sozzani, S.2    Zhou, D.3    Weich, H.A.4    Mantovani, A.5    Marme, D.6
  • 55
    • 0034021278 scopus 로고    scopus 로고
    • Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer
    • DOI 10.1002/(SICI)1096-9896(200003)190:4<430::AID-PATH538>3.0.CO;2- 6
    • Leek R. D., N. C. Hunt, R. J. Landers, C. E. Lewis, J. A. Royds & A. L. Harris: Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer. J Pathol 190, 430-436 (2000) (Pubitemid 30163582)
    • (2000) Journal of Pathology , vol.190 , Issue.4 , pp. 430-436
    • Leek, R.D.1    Hunt, N.C.2    Landers, R.J.3    Lewis, C.E.4    Royds, J.A.5    Harris, A.L.6
  • 57
    • 0031868964 scopus 로고    scopus 로고
    • Invasive lobular and invasive ductal carcinoma of the breast show distinct patterns of vascular endothelial growth factor expression and angiogenesis
    • DOI 10.1002/(SICI)1096-9896(199808)185:4<394::AID-PATH117>3.0.CO;2- S
    • Lee A. H., E. A. Dublin, L. G. Bobrow & R. Poulsom: Invasive lobular and invasive ductal carcinoma of the breast show distinct patterns of vascular endothelial growth factor expression and angiogenesis. J Pathol 185, 394-401 (1998) (Pubitemid 28355972)
    • (1998) Journal of Pathology , vol.185 , Issue.4 , pp. 394-401
    • Lee, A.H.S.1    Dublin, E.A.2    Bobrow, L.G.3    Poulsom, R.4
  • 58
    • 0033780453 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularised areas of breast carcinomas
    • Lewis J. S., R. J. Landers, J. C. Underwood, A. L. Harris & C. E. Lewis: Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularised areas of breast carcinomas. J Pathol 192, 150-158 (2000)
    • (2000) J Pathol , vol.192 , pp. 150-158
    • Lewis, J.S.1    Landers, R.J.2    Underwood, J.C.3    Harris, A.L.4    Lewis, C.E.5
  • 60
    • 0037467569 scopus 로고    scopus 로고
    • Endothelin-1: A multifunctional molecule in cancer
    • Grant K., M. Loizidou & I. Taylor: Endothelin-1: a multifunctional molecule in cancer. Br J Cancer 88, 163-166 (2003)
    • (2003) Br J Cancer , vol.88 , pp. 163-166
    • Grant, K.1    Loizidou, M.2    Taylor, I.3
  • 61
    • 0036740130 scopus 로고    scopus 로고
    • Endothelin-2 is a macrophage chemoattractant: Implications for macrophage distribution in tumors
    • Grimshaw M. J., J. L. Wilson & F. R. Balkwill: Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors. Eur J Immunol 32, 2393-2400 (2002)
    • (2002) Eur J Immunol , vol.32 , pp. 2393-2400
    • Grimshaw, M.J.1    Wilson, J.L.2    Balkwill, F.R.3
  • 62
    • 0034890356 scopus 로고    scopus 로고
    • A novel bioactive 31-amino acid endothelin-1 is a potent chemotactic peptide for human neutrophils and monocytes
    • Cui P., K. Tani, H. Kitamura, Y. Okumura, M. Yano, D. Inui, T. Tamaki, S. Sone & H. Kido: A novel bioactive 31-amino acid endothelin-1 is a potent chemotactic peptide for human neutrophils and monocytes. J Leukoc Biol 70, 306-312 (2001) (Pubitemid 32751523)
    • (2001) Journal of Leukocyte Biology , vol.70 , Issue.2 , pp. 306-312
    • Cui, P.1    Tani, K.2    Kitamura, H.3    Okumura, Y.4    Yano, M.5    Inui, D.6    Tamaki, T.7    Sone, S.8    Kido, H.9
  • 63
    • 0038380366 scopus 로고    scopus 로고
    • Endothelin-2 is a hypoxia-induced autocrine survival factor for breast tumour cells
    • Grimshaw M. J., S. Naylor & F. R. Balkwill: Endothelin-2 is a hypoxia-induced autocrine survival factor for breast tumour cells. Mol Cancer Ther 9, 1273-1281 (2002)
    • (2002) Mol Cancer Ther , vol.9 , pp. 1273-1281
    • Grimshaw, M.J.1    Naylor, S.2    Balkwill, F.R.3
  • 67
    • 2942620525 scopus 로고    scopus 로고
    • Hypoxia inhibits the expression of the CCR5 chemokine receptor in macrophages
    • DOI 10.1016/j.cellimm.2004.03.006, PII S0008874904000309
    • Bosco M. C., G. Reffo, M. Puppo & L. Varesio: Hypoxia inhibits the expression of the CCR5 chemokine receptor in macrophages. Cell Immunol 228, 1-7 (2004) (Pubitemid 38760116)
    • (2004) Cellular Immunology , vol.228 , Issue.1 , pp. 1-7
    • Bosco, M.C.1    Reffo, G.2    Puppo, M.3    Varesio, L.4
  • 68
    • 0031801052 scopus 로고    scopus 로고
    • Hypoxia down-regulates MCP-1 expression: Implications for macrophage distribution in tumors
    • Negus R. P., L. Turner, F. Burke & F. R. Balkwill: Hypoxia down-regulates MCP-1 expression: implications for macrophage distribution in tumours. J Leukoc Biol 63, 758-765 (1998) (Pubitemid 28274839)
    • (1998) Journal of Leukocyte Biology , vol.63 , Issue.6 , pp. 758-765
    • Negus, R.P.M.1    Turner, L.2    Burke, F.3    Balkwill, F.R.4
  • 70
    • 0030944928 scopus 로고    scopus 로고
    • Quantitative assessment of the leukocyte infiltrate in ovarian cancer and its relationship to the expression of C-C chemokines
    • Negus R. P., G. W. Stamp, J. Hadley & F. R. Balkwill: Quantitative assessment of the leukocyte infiltrate in ovarian cancer and its relationship to the expression of C-C chemokines. Am J Pathol 150, 1723-1734 (1997) (Pubitemid 27193819)
    • (1997) American Journal of Pathology , vol.150 , Issue.5 , pp. 1723-1734
    • Negus, R.P.M.1    Stamp, G.W.H.2    Hadley, J.3    Balkwill, F.R.4
  • 71
    • 0037223573 scopus 로고    scopus 로고
    • Up-regulation of macrophage migration inhibitory factor gene and protein expression in glial tumor cells during hypoxic and hypoglycemic stress indicates a critical role for angiogenesis in glioblastoma multiforme
    • Bacher M., J. Schrader, N. Thompson, K. Kuschela, D. Gemsa, G. Waeber & J. Schlegel: Up-regulation of macrophage migration inhibitory factor gene and protein expression in glial tumour cells during hypoxic and hypoglycaemic stress indicates a critical role for abgiogenesis in glioblastoma multiforme. Am J Pathol 162, 11-17 (2003) (Pubitemid 36041985)
    • (2003) American Journal of Pathology , vol.162 , Issue.1 , pp. 11-17
    • Bacher, M.1    Schrader, J.2    Thompson, N.3    Kuschela, K.4    Gemsa, D.5    Waeber, G.6    Schlegel, J.7
  • 72
    • 0141927332 scopus 로고    scopus 로고
    • Genes commonly upregulated by hypoxia in human breast cancer cells MCF-7 and MDA-MB-231
    • DOI 10.1016/S0753-3322(03)00098-2
    • Bando H., M. Toi, K. Kitada & M. Koike: Genes commonly upregulated by hypoxia in human breast cancer cells MCF-7 and MDA-MB-231. Biomed Pharmacother 57, 333-340 (2003) (Pubitemid 37237600)
    • (2003) Biomedicine and Pharmacotherapy , vol.57 , Issue.8 , pp. 333-340
    • Bando, H.1    Toi, M.2    Kitada, K.3    Koike, M.4
  • 73
    • 0345118952 scopus 로고    scopus 로고
    • Genetic amplification of the transcriptional response to hypoxia as a novel means of identifying regulators of angiogenesis
    • DOI 10.1016/S0888-7543(03)00215-5
    • White J. R., R. A. Harris, S. R. Lee, M. H. Craigon, K. Binley, T. Price, G. L. Beard, C. R. Mundy & S. Naylor: Genetic amplification of the transcriptional response to hypoxia as a novel means of identifying regulators of angiogenesis. Genomics 83, 1-8 (2004) (Pubitemid 37518254)
    • (2004) Genomics , vol.83 , Issue.1 , pp. 1-8
    • White, J.R.1    Harris, R.A.2    Lee, S.R.3    Craigon, M.H.4    Binley, K.5    Price, T.6    Beard, G.L.7    Mundy, C.R.8    Naylor, S.9
  • 74
    • 0013923944 scopus 로고
    • Delayed hypersensitivity in vitro: Its mediation by cell-free substances formed by lymphoid cellantigen interaction
    • David J. R.: Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cellantigen interaction. Proc Natl Acad Sci USA 56, 72-77 (1966)
    • (1966) Proc Natl Acad Sci USA , vol.56 , pp. 72-77
    • David, J.R.1
  • 75
    • 0013933261 scopus 로고
    • Mechanism of a reaction in vitro associated with delayed-type hypersensitivity
    • Bloom B. R. & B. Bennett: Mechanism of a reaction in vitro associated with delayed-type hypersensitivity. Science 153, 80-82 (1966)
    • (1966) Science , vol.153 , pp. 80-82
    • Bloom, B.R.1    Bennett, B.2
  • 76
    • 0242384068 scopus 로고    scopus 로고
    • Mechanisms and effectors of MIF-dependent promotion of tumourigenesis
    • DOI 10.1016/j.cellsig.2003.07.002
    • Mitchell R. A.: Mechanisms and effectors of MIF-dependent promotion of tumourigenesis. Cell Signal 16, 13-19 (2004) (Pubitemid 37357187)
    • (2004) Cellular Signalling , vol.16 , Issue.1 , pp. 13-19
    • Mitchell, R.A.1
  • 77
    • 33746215136 scopus 로고    scopus 로고
    • Hypoxia modifies the transcriptome of primary human monocytes: Modulation of novel immune-related genes and identification of CC-chemokine ligand 20 as a new hypoxia-inducible gene
    • Bosco M. C., M. Puppo, C. Santangelo, L. Anfosso, U. Pfeffer, P. Fardin, F. Battaglia & L. Varesio: Hypoxia modifies the transcriptome of primary human monocytes: modulation of novel immune-related genes and identification of CC-chemokine ligand 20 as a new hypoxia-inducible gene. J Immunol 177, 1941-1955 (2006) (Pubitemid 44092535)
    • (2006) Journal of Immunology , vol.177 , Issue.3 , pp. 1941-1955
    • Bosco, M.C.1    Puppo, M.2    Santangelo, C.3    Anfosso, L.4    Pfeffer, U.5    Fardin, P.6    Battaglia, F.7    Varesio, L.8
  • 80
    • 0035101398 scopus 로고    scopus 로고
    • Inhibition of monocyte and macrophage chemotaxis by hypoxia and inflammation - A potential mechanism
    • DOI 10.1002/1521-4141(200102)31:2<480::AID-IMMU480>3.0.CO;2-L
    • Grimshaw M. J. & F. R. Balkwill: Inhibition of macrophage chemotaxis by hypoxia and inflammation - a potential mechanism. Eur J Immunol 31, 480-489 (2001) (Pubitemid 32166603)
    • (2001) European Journal of Immunology , vol.31 , Issue.2 , pp. 480-489
    • Grimshaw, M.J.1    Balkwill, F.R.2
  • 81
    • 0030734010 scopus 로고    scopus 로고
    • P38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells
    • Rouseau S., F. Houle, J. Landry & J. Huot: p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganisation and cell migration in human endothelial cells. Oncogene 15, 2169-2177 (1997) (Pubitemid 27493906)
    • (1997) Oncogene , vol.15 , Issue.18 , pp. 2169-2177
    • Rousseau, S.1    Houle, F.2    Landry, J.3    Huot, J.4
  • 82
    • 0003090004 scopus 로고    scopus 로고
    • The role of macrophages in tumour angiogenesis
    • Eds: Bicknell R., Lewis C. E. Oxford University Press, Oxford, UK
    • Leek R. D., C. E. Lewis & A. L. Harris: The role of macrophages in tumour angiogenesis. In: Tumour Angiogenesis. Eds: Bicknell R., Lewis C. E. Oxford University Press, Oxford, UK (1997)
    • (1997) Tumour Angiogenesis
    • Leek, R.D.1    Lewis, C.E.2    Harris, A.L.3
  • 83
    • 27944473690 scopus 로고    scopus 로고
    • VEGF as a key mediator of angiogenesis in cancer
    • DOI 10.1159/000088478
    • Carmeliet P.: VEGF as a key mediator of angiogenesis in cancer. Oncology 69, 4-10 (2005) (Pubitemid 41680947)
    • (2005) Oncology , vol.69 , Issue.SUPPL. 3 , pp. 4-10
    • Carmeliet, P.1
  • 84
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - A key regulatory factor in tumour growth
    • Harris A. L.: Hypoxia - a key regulatory factor in tumour growth. Nat Rev Cancer 2, 38-47 (2002) (Pubitemid 37328806)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.1 , pp. 38-47
    • Harris, A.L.1
  • 86
    • 0035834409 scopus 로고    scopus 로고
    • A conserved family of prolyl-4-hydroxylases that modify HIF
    • DOI 10.1126/science.1066373
    • Bruick R. K. & S. L. McKnight. A conserved family of prolyl-4-hydroxylases that modify HIF. Science 294, 1337-40 (2001) (Pubitemid 33063099)
    • (2001) Science , vol.294 , Issue.5545 , pp. 1337-1340
    • Bruick, R.K.1    McKnight, S.L.2
  • 88
    • 0032100732 scopus 로고    scopus 로고
    • HIF-1α is required for solid tumor formation and embryonic vascularization
    • DOI 10.1093/emboj/17.11.3005
    • Ryan H. E., J. Lo, R. S. Johnson: HIF-1 alpha is required for solid tumour formation and embryonic vascularisation. EMBO 17, 3005-3015 (1998) (Pubitemid 28254373)
    • (1998) EMBO Journal , vol.17 , Issue.11 , pp. 3005-3015
    • Ryan, H.E.1    Lo, J.2    Johnson, R.S.3
  • 90
    • 0036007293 scopus 로고    scopus 로고
    • Expression of HIF-Iα by human macrophages: Implications for the use of macrophages in hypoxia-regulated cancer gene therapy
    • DOI 10.1002/path.1029
    • Burke B., T. N. Tang, K. P. Corke, D. Tazzyman, K. Ameri, M. Wells & C. E. Lewis: Expression of HIF-1 alpha by human macrophages: implications for the use of macrophages in hypoxia-regulated cancer therapy. J Pathol 196, 204-12 (2002) (Pubitemid 34110902)
    • (2002) Journal of Pathology , vol.196 , Issue.2 , pp. 204-212
    • Burke, B.1    Tang, N.2    Corke, K.P.3    Tazzyman, D.4    Ameri, K.5    Wells, M.6    Lewis, C.E.7
  • 91
    • 0033870281 scopus 로고    scopus 로고
    • The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages
    • Talks K. L., H. Turley, K. C. Gatter, P. H. Maxwell, C. W. Pugh, P. J. Ratcliffe & A. L. Harris: The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol 157, 411-421 (2000) (Pubitemid 30626905)
    • (2000) American Journal of Pathology , vol.157 , Issue.2 , pp. 411-421
    • Talks, K.L.1    Turley, H.2    Gatter, K.C.3    Maxwell, P.H.4    Pugh, C.W.5    Ratcliffe, P.J.6    Harris, A.L.7
  • 92
    • 0036493984 scopus 로고    scopus 로고
    • Relation of hypoxia-inducible factor-2α (HIF-2α) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer
    • Leek R. D., K. L. Talks, F. Pezzella, H. Turley, L. Campo, N. S. Brown, R. Bicknell, M. Taylor, K. C. Gatter & A. L. Harris: Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer. Cancer Res 62, 1326-1329 (2002) (Pubitemid 34407787)
    • (2002) Cancer Research , vol.62 , Issue.5 , pp. 1326-1329
    • Leek, R.D.1    Talks, K.L.2    Pezzella, F.3    Turley, H.4    Campo, L.5    Brown, N.S.6    Bicknell, R.7    Taylor, M.8    Gatter, K.C.9    Harris, A.L.10
  • 93
    • 0036190869 scopus 로고    scopus 로고
    • Hypoxia-induced, perinecrotic expression of endothelial Per-ARNT-Sim domain protein-1/hypoxia-inducible factor-2α correlates with tumor progression, vascularization, and focal macrophage infiltration in bladder cancer
    • Onita T., P. G. Ji, J. W. Xuan, H. Sakai, H. Kanetake, P. H. Maxwell, G. H. Fong, M. Y. Gabril, M. Moussa & J. L. Chin: Hypoxia-induced, perinecrotic expression of endothelial Per-ARNT-Sim domain protein-1/hypoxiainducible factor-2alpha correlates with tumor progression, vascularization, and focal macrophage infiltration in bladder cancer. Clin Cancer Res 8, 471-480 (2002) (Pubitemid 34193967)
    • (2002) Clinical Cancer Research , vol.8 , Issue.2 , pp. 471-480
    • Onita, T.1    Guang Ji, P.2    Xuan, J.W.3    Sakai, H.4    Kanetake, H.5    Maxwell, P.H.6    Fong, G.-H.7    Gabril, M.Y.8    Moussa, M.9    Chin, J.L.10
  • 94
    • 0038115172 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1α (HIF-1α) accumulation via redox-dependent mechanisms
    • Shatrov V. A., V. V. Sumbayev, J. Zhou & B. Brune: Oxidised low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1a (HIF-1a) accumulation via redox-dependent mechanisms. Blood 101, 4847-4849 (2003) (Pubitemid 36857745)
    • (2003) Blood , vol.101 , Issue.12 , pp. 4847-4849
    • Shatrov, V.A.1    Sumbayev, V.V.2    Zhou, J.3    Brune, B.4
  • 95
    • 1642581653 scopus 로고    scopus 로고
    • Hypoxic gene activation by lipopolysaccharide in macrophages: Implication of hypoxia-inducible factor 1α
    • DOI 10.1182/blood-2003-07-2427
    • Blouin C. C., E. L. Page, G. M. Soucy & D. E. Richard: Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1a. Blood 103, 1124-1130 (2004) (Pubitemid 38129580)
    • (2004) Blood , vol.103 , Issue.3 , pp. 1124-1130
    • Blouin, C.C.1    Page, E.L.2    Soucy, G.M.3    Richard, D.E.4
  • 97
    • 33645080666 scopus 로고    scopus 로고
    • Normoxic stabilisation of hypoxia-inducible factor-1 alpha by modulation of the labile iron pool in differentiating u937 macrophages: Effect of natural resistance-associated macrophage protein 1
    • Knowles H. J., D. R. Mole, P. J. Ratcliffe & A. L. Harris: Normoxic stabilisation of Hypoxia-Inducible Factor-1 alpha by modulation of the labile iron pool in differentiating U937 macrophages: effect of Natural Resistance-Associated Macrophage Protein 1. Cancer Res 66, 2600-2607 (2006)
    • (2006) Cancer Res , vol.66 , pp. 2600-2607
    • Knowles, H.J.1    Mole, D.R.2    Ratcliffe, P.J.3    Harris, A.L.4
  • 101
    • 0032947103 scopus 로고    scopus 로고
    • Macrophages and microvessel density in tumors of the ovary
    • DOI 10.1006/gyno.1998.5292
    • Orre M. & P. A. Rogers: Macrophages and microvessel density in tumours of the ovary. Gynecol Oncol 73, 47-50 (1999) (Pubitemid 29177598)
    • (1999) Gynecologic Oncology , vol.73 , Issue.1 , pp. 47-50
    • Orre, M.1    Rogers, P.A.W.2
  • 102
    • 0036834136 scopus 로고    scopus 로고
    • Infiltration of tumour-associated macrophages in human oral squamous carcinoma
    • Li C., S. Shintani, N. Terakado, K. Nakashiro & H. Hamakawa: Infiltration of tumour-associated macrophages in human oral squamous carcinoma. Oncol Rep 9, 1219-1223 (2002)
    • (2002) Oncol Rep , vol.9 , pp. 1219-1223
    • Li, C.1    Shintani, S.2    Terakado, N.3    Nakashiro, K.4    Hamakawa, H.5
  • 103
    • 0033067163 scopus 로고    scopus 로고
    • Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast
    • DOI 10.1038/sj.bjc.6690158
    • Leek R. D., R. J. Landers, A. L. Harris & C. E. Lewis: Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast. Br J Cancer 79, 991-995 (1999) (Pubitemid 29082138)
    • (1999) British Journal of Cancer , vol.79 , Issue.5-6 , pp. 991-995
    • Leek, R.D.1    Landers, R.J.2    Harris, A.L.3    Lewis, C.E.4
  • 105
    • 30644457353 scopus 로고    scopus 로고
    • Macrophages promote angiogenesis in human breast tumour spheroids in vivo
    • DOI 10.1038/sj.bjc.6602901, PII 6602901
    • Bingle L., C. E. Lewis, K. P. Corke, M. W. Reed & N. J. Brown: Macrophages promote angiogenesis in human breast tumour spheroids in vivo. Br J Cancer 94, 101-107 (2006) (Pubitemid 43088548)
    • (2006) British Journal of Cancer , vol.94 , Issue.1 , pp. 101-107
    • Bingle, L.1    Lewis, C.E.2    Corke, K.P.3    Reed, M.4    Brown, N.J.5
  • 107
    • 13944252559 scopus 로고    scopus 로고
    • Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2α in von Hippel-Lindau renal cell carcinoma
    • DOI 10.1038/sj.onc.1208305
    • Petrella B. L., J. Lohi & C. E. Brinkerhoff: Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2 alpha in von Hippel Lindau renal cell carcinoma. Oncogene 24, 1043-1052 (2005) (Pubitemid 40313881)
    • (2005) Oncogene , vol.24 , Issue.6 , pp. 1043-1052
    • Petrella, B.L.1    Lohi, J.2    Brinckerhoff, C.E.3
  • 108
    • 0141425768 scopus 로고    scopus 로고
    • Hypoxia-induced gene expression in human macrophages: Implications for ischemic tissues and hypoxia-regulated gene therapy
    • Burke B., A. Giannoudis, K. P. Corke, D. Gill, M. Wells, L. Ziegler-Heitbrock & C. E. Lewis: Hypoxiainduced gene expression in human macrophages: implications for ischemic tissues and hypoxia-regulated gene therapy. Am J Pathol 163, 1233-1243 (2003) (Pubitemid 37175073)
    • (2003) American Journal of Pathology , vol.163 , Issue.4 , pp. 1233-1243
    • Burke, B.1    Giannoudis, A.2    Corke, K.P.3    Gill, D.4    Wells, M.5    Ziegler-Heitbrock, L.6    Lewis, C.E.7
  • 110
    • 4944239035 scopus 로고    scopus 로고
    • An amino-bisphosphonate targets MMP-9 - Expressing macrophages and angiogenesis to impair cervical carcinogenesis
    • DOI 10.1172/JCI200422087
    • Giraudo E., M. Inoue & D. Hanahan: An aminobisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis. J Clin Invest 114, 623-633 (2004) (Pubitemid 39578752)
    • (2004) Journal of Clinical Investigation , vol.114 , Issue.5 , pp. 623-633
    • Giraudo, E.1    Inoue, M.2    Hanahan, D.3
  • 112
    • 0031876708 scopus 로고    scopus 로고
    • Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in macrophages correlates with tumor angiogenesis and prognosis in invasive breast cancer
    • Nagaoka H., Y. Iino, H. Takei & Y. Morishita: Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in macrophages correlates with tumour angiogenesis and prognosis in invasive breast cancer. Int J Oncol 13, 449-454 (1998) (Pubitemid 28372665)
    • (1998) International Journal of Oncology , vol.13 , Issue.3 , pp. 449-454
    • Nagaoka, H.1    Iino, Y.2    Takei, H.3    Morishita, Y.4
  • 114
    • 0031800372 scopus 로고    scopus 로고
    • Association of tumour necrosis factor alpha and its receptors with thymidine phosphorylase expression in invasive breast carcinoma
    • Leek R. D., R. Landers, S. B. Fox, F. Ng, A. L. Harris & C. E. Lewis: Association of tumour necrosis factor alpha and its receptors with thymidine phosphorylase expression in invasive breast carcinoma. Br J Cancer 77, 2246-2251 (1998) (Pubitemid 28263948)
    • (1998) British Journal of Cancer , vol.77 , Issue.12 , pp. 2246-2251
    • Leek, R.D.1    Landers, R.2    Fox, S.B.3    Ng, F.4    Harris, A.L.5    Lewis, C.E.6
  • 115
    • 0035678053 scopus 로고    scopus 로고
    • Macrophage infiltration-associated thymidine phosphorylase expression correlates with increased microvessel density and poor prognosis in astrocytic tumors
    • Yao Y., T. Kubota, K. Sato & R. Kitai: Macrophage infiltration-associated thymidine phosphorylase expression correlates with increased microvessel density and poor prognosis in astrocytic tumours. Clin Cancer Res 7, 4021-4026 (2001) (Pubitemid 34044622)
    • (2001) Clinical Cancer Research , vol.7 , Issue.12 , pp. 4021-4026
    • Yao, Y.1    Kubota, T.2    Sato, K.3    Kitai, R.4
  • 116
    • 3342904989 scopus 로고    scopus 로고
    • Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteinases
    • Hagemann T., S. C. Robinson, M. Schulz, L. Trumper, F. R. Balkwill & C. Binder: Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteinases. Carcinogenesis 25, 1542-1549 (2004)
    • (2004) Carcinogenesis , vol.25 , pp. 1542-1549
    • Hagemann, T.1    Robinson, S.C.2    Schulz, M.3    Trumper, L.4    Balkwill, F.R.5    Binder, C.6
  • 117
    • 0023681769 scopus 로고
    • Induction of monocyte migration by recombinant macrophage colony-stimulating factor
    • Wang J. M., J. D. Griffin, A. Rambaldi, Z. G. Chen & A. Mantovani: Induction of monocyte migration by recombinant macrophage colony-stimulating factor. J Immunol 141, 575-579 (1988)
    • (1988) J Immunol , vol.141 , pp. 575-579
    • Wang, J.M.1    Griffin, J.D.2    Rambaldi, A.3    Chen, Z.G.4    Mantovani, A.5
  • 118
    • 3442901908 scopus 로고    scopus 로고
    • Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice
    • DOI 10.1158/0008-5472.CAN-04-0961
    • Aharinejad S., P. Paulus, M. Sioud, M. Hofmann, K. Zins, R. Schafer, E. R. Stanley & D. Abraham: Colonystimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumour xenografts in mice. Cancer Res 64, 5378-5384 (2004) (Pubitemid 39006559)
    • (2004) Cancer Research , vol.64 , Issue.15 , pp. 5378-5384
    • Aharinejad, S.1    Paulus, P.2    Sioud, M.3    Hofmann, M.4    Zins, K.5    Schafer, R.6    Stanley, E.R.7    Abraham, D.8
  • 119
    • 0035911221 scopus 로고    scopus 로고
    • Colony stimulating factor 1 promotes progression of mammary tumours to malignancy
    • Lin E. Y., A. V. Nguyen, R. G. Russell & J. W. Pollard: Colony stimulating factor 1 promotes progression of mammary tumours to malignancy. J Exp Med 193, 727-740 (2001)
    • (2001) J Exp Med , vol.193 , pp. 727-740
    • Lin, E.Y.1    Nguyen, A.V.2    Russell, R.G.3    Pollard, J.W.4
  • 120
    • 31044433663 scopus 로고    scopus 로고
    • Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis
    • DOI 10.1016/j.cell.2006.01.007, PII S0092867406000559
    • Condeelis J. & J. W. Pollard: Macrophages: obligate partners for tumor cell migration, invasion and metastasis. Cell 124, 263-266 (2006) (Pubitemid 43121975)
    • (2006) Cell , vol.124 , Issue.2 , pp. 263-266
    • Condeelis, J.1    Pollard, J.W.2
  • 121
    • 0028268629 scopus 로고
    • Hypoxia causes the activation of nuclear factor κB through the phosphorylation of IκBα on tyrosine residues
    • Chen A. C., E. Y. Chen & A. J. Giaccia: Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues. Cancer Res 54, 1425-1430 (1994) (Pubitemid 24106401)
    • (1994) Cancer Research , vol.54 , Issue.6 , pp. 1425-1430
    • Koong, A.C.1    Chen, E.Y.2    Giaccia, A.J.3
  • 123
    • 0347719258 scopus 로고    scopus 로고
    • The Transcription Factors Hypoxia-Inducible Factor 1α and Ets-1 Colocalize in the Hypoxic Synovium of Inflamed Joints in Adjuvant-Induced Arthritis
    • DOI 10.1002/art.11473
    • Peters C. L., C. J. Morris, P. I. Mappm, D. R. Blake, C. E. Lewis & V. R. Winrow: The transcription factors hypoxia-inducible factor 1alpha and Ets-1 colocalize in the hypoxic synovium of inflamed joints in adjuvant-induced arthritis. Arthritis Rheum 50, 291-296 (2004) (Pubitemid 38084314)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.1 , pp. 291-296
    • Peters, C.L.1    Morris, C.J.2    Mapp, P.I.3    Blake, D.R.4    Lewis, C.E.5    Winrow, V.R.6
  • 124
    • 0033692793 scopus 로고    scopus 로고
    • Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors
    • Brown N. S., A. Jones, C. Fujiyama, A. L. Harris & R. Bicknell: Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors. Cancer Res 60, 6298-6302 (2000)
    • (2000) Cancer Res , vol.60 , pp. 6298-6302
    • Brown, N.S.1    Jones, A.2    Fujiyama, C.3    Harris, A.L.4    Bicknell, R.5
  • 127
    • 12244287614 scopus 로고    scopus 로고
    • Independent prognostic impact of lymphatic vessel density and presence of low-grade lymphangiogenesis in cutaneous melanoma
    • Straume O., D. G. Jackson & L. A. Akslen: Independent prognostic impact of lymphatic vessel density and presence of low-grade lymphangiogenesis in cutaneous melanoma. Clin Cancer Res 9, 250-256 (2003) (Pubitemid 36109741)
    • (2003) Clinical Cancer Research , vol.9 , Issue.1 , pp. 250-256
    • Straume, O.1    Jackson, D.G.2    Akslen, L.A.3
  • 128
    • 33745165865 scopus 로고    scopus 로고
    • VEGF-C expressing tumor-associated macrophages in lymph node positive breast cancer: impact on lymphangiogenesis and survival
    • DOI 10.1016/j.surg.2005.12.008, PII S0039606006000286
    • Schoppman S. F., A. Fenzl, K. Nagy, S. Unger, G. Bayer, S. Geleff, M. Gnant, R. Horvat, R. Jakesz & P. Birner: VEGF-C expressing tumour-associated macrophages in lymph node positive breast cancer: impact on lymphangiogenesis and survival. Surgery 139, 839-846 (2006) (Pubitemid 43902914)
    • (2006) Surgery , vol.139 , Issue.6 , pp. 839-846
    • Schoppmann, S.F.1    Fenzl, A.2    Nagy, K.3    Unger, S.4    Bayer, G.5    Geleff, S.6    Gnant, M.7    Horvat, R.8    Jakesz, R.9    Birner, P.10
  • 132
    • 4944229701 scopus 로고    scopus 로고
    • A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors
    • DOI 10.1158/0008-5472.CAN-04-1449
    • Wyckoff J., W. Wang, E. Y. Lin, Y. Wang, F. Pixley, E. R. Stanley, T. Graf, J. W. Pollard, J. Segall & J. Condeelis: A paracrine loop between tumour cells and macrophages is required for tumour cell migration in mammary tumours. Cancer Res 64, 7022-7029 (2004) (Pubitemid 39331012)
    • (2004) Cancer Research , vol.64 , Issue.19 , pp. 7022-7029
    • Wyckoff, J.1    Wang, W.2    Lin, E.Y.3    Wang, Y.4    Pixley, F.5    Stanley, E.R.6    Graf, T.7    Pollard, J.W.8    Segall, J.9    Condeelis, J.10
  • 133
    • 20444436815 scopus 로고    scopus 로고
    • Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop
    • DOI 10.1158/0008-5472.CAN-04-1853
    • Goswami S., E. Sahai, J. B. Wyckoff, M. Cammer, D. Cox, F. J. Pixley, E. R. Stanley, J. E. Segall & J. S. Condeelis: Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop. Cancer Res 65, 5278-5283 (2005) (Pubitemid 40827339)
    • (2005) Cancer Research , vol.65 , Issue.12 , pp. 5278-5283
    • Goswami, S.1    Sahai, E.2    Wyckoff, J.B.3    Cammer, M.4    Cox, D.5    Pixley, F.J.6    Stanley, E.R.7    Segall, J.E.8    Condeelis, J.S.9
  • 135
    • 0031709864 scopus 로고    scopus 로고
    • Tumor-induced immune dysfunction: The macrophage connection
    • Elgert K. D., D. G. Alleva & D. W. Mullins: Tumourinduced immune dysfunction: the macrophage connection. J Leukoc Biol 64, 275-290 (1998) (Pubitemid 28409233)
    • (1998) Journal of Leukocyte Biology , vol.64 , Issue.3 , pp. 275-290
    • Elgert, K.D.1    Alleva, D.G.2    Mullins, D.W.3
  • 136
    • 31344442461 scopus 로고    scopus 로고
    • Inflammation-associated immune suppression in cancer: The roles played by cytokines, chemokines and additional mediators
    • DOI 10.1016/j.semcancer.2005.07.006, PII S1044579X05000593, The
    • Ben-Baruch A.: Inflammation-associated immune suppression in cancer: the roles played by cytokines, chemokines and additional mediators. Semin Cancer Biol 16, 38-52 (2006) (Pubitemid 43139708)
    • (2006) Seminars in Cancer Biology , vol.16 , Issue.1 , pp. 38-52
    • Ben-Baruch, A.1
  • 137
    • 33645089186 scopus 로고    scopus 로고
    • Defective antitumour function of monocyte-derived macrophages from epithelial ovarian cancer patients
    • Gordon I. O. & R. S. Freedman: Defective antitumour function of monocyte-derived macrophages from epithelial ovarian cancer patients. Clin Cancer Res 12, 1515-1524 (2006)
    • (2006) Clin Cancer Res , vol.12 , pp. 1515-1524
    • Gordon, I.O.1    Freedman, R.S.2
  • 138
    • 17444405573 scopus 로고    scopus 로고
    • PGE/cAMP and GM-CSF synergise to induce a pro-tolerance cytokine profile in monocytic cell lines
    • DOI 10.1016/j.bbrc.2005.03.137
    • Grant V., A. E. King, E. Faccenda & R. W. Kelly: PGE/cAMP and GM-CSF synergise to induce a protolerance cytokine profile in monocytic cell lines. Biochem Biophys Res Commun 331, 187-193 (2005) (Pubitemid 40545160)
    • (2005) Biochemical and Biophysical Research Communications , vol.331 , Issue.1 , pp. 187-193
    • Grant, V.1    King, A.E.2    Faccenda, E.3    Kelly, R.W.4
  • 139
    • 10744228469 scopus 로고    scopus 로고
    • Macrophages transduced with an adenoviral vector expressing interleukin 12 suppress tumour growth and metastasis in a preclinical metastatic prostate cancer model
    • Satoh T., T. Saika, S. Ebara, N. Kusaka, T. L. Timme, G. Yang, J. Wang, V. Mouraviev, G. Cao, M. A. el Fattah & T. C. Thompson: Macrophages transduced with an adenoviral vector expressing interleukin 12 suppress tumour growth and metastasis in a preclinical metastatic prostate cancer model. Cancer Res 63, 853-7860 (2003)
    • (2003) Cancer Res , vol.63 , pp. 853-7860
    • Satoh, T.1    Saika, T.2    Ebara, S.3    Kusaka, N.4    Timme, T.L.5    Yang, G.6    Wang, J.7    Mouraviev, V.8    Cao, G.9    El Fattah, M.A.10    Thompson, T.C.11
  • 140
    • 33644775602 scopus 로고    scopus 로고
    • An oligonucleotide decoy for Stat3 activates the immune response of macrophages to breast cancer
    • DOI 10.1016/j.imbio.2005.11.004, PII S0171298506000167
    • Sun Z., Z. Yao, S. Liu, H. Tang & X. Yan: An oligonucleotide decoy for Stat3 activates the immune response of macrophages to breast cancer. Immunobiology 211, 199-209 (2006) (Pubitemid 43337760)
    • (2006) Immunobiology , vol.211 , Issue.3 , pp. 199-209
    • Sun, Z.1    Yao, Z.2    Liu, S.3    Tang, H.4    Yan, X.5
  • 141
    • 0035216956 scopus 로고    scopus 로고
    • Matrilysin [MMP-7] expression selects for cells with reduced sensitivity to apoptosis
    • DOI 10.1038/sj.neo.7900190
    • Fingleton B., T. Vargo-Gogola, H. C. Crawford & L. M. Matrisian: Matrilysin (MMP-7) expression selects for cells with reduced sensitivity to apoptosis. Neoplasia 3, 459-468 (2001) (Pubitemid 33151012)
    • (2001) Neoplasia , vol.3 , Issue.6 , pp. 459-468
    • Fingleton, B.1    Vargo-Gogola, T.2    Crawford, H.C.3    Matrisian, L.M.4
  • 142
    • 10744224063 scopus 로고    scopus 로고
    • The Degree of Macrophage Infiltration into the Cancer Cell Nest is a Significant Predictor of Survival in Gastric Cancer Patients
    • Ohno S., H. Inagawa, D. K. Dhar, T. Fujii, S. Ueda, M. Tachibana, N. Suzuki, M. Inoue, G. Soma & N. Nagasue: The degree of macrophage infiltration into the cancer cell nest is a significant predictor of survival in gastric cancer patients. Anticancer Res 23, 5015-5022 (2003) (Pubitemid 38182119)
    • (2003) Anticancer Research , vol.23 , Issue.6 D , pp. 5015-5022
    • Ohno, S.1    Inagawa, H.2    Dhar, D.K.3    Fujii, T.4    Ueda, S.5    Tachibana, M.6    Suzuki, N.7    Inoue, M.8    Soma, G.-I.9    Nagasue, N.10
  • 145
    • 33845535091 scopus 로고    scopus 로고
    • The multifaceted roles of chemokines in malignancy
    • DOI 10.1007/s10555-006-9003-5, Special Issue on Pro-inflammatory Cytokines in Cancer
    • Ben-Baruch A.: The multifaceted roles of chemokines in malignancy. Cancer Metastasis Rev 25, 357-371 (2006) (Pubitemid 44922355)
    • (2006) Cancer and Metastasis Reviews , vol.25 , Issue.3 , pp. 357-371
    • Ben-Baruch, A.1
  • 147
    • 0027169811 scopus 로고
    • IP-10, a -C-X-C- chemokine, elicits a potent thymus-dependent antitumor response in vivo
    • Luster A. D. & P. Leder: IP-10, a C-X-C chemokine, elicits a potent thymus-dependent antitumour response in vivo. J Exp Med 178, 1057-1065 (1993) (Pubitemid 23260444)
    • (1993) Journal of Experimental Medicine , vol.178 , Issue.3 , pp. 1057-1065
    • Luster, A.D.1    Leder, P.2
  • 148
    • 0035085442 scopus 로고    scopus 로고
    • Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity
    • DOI 10.1038/sj.gt.3301386
    • Palmer K., M. Hitt, P. C. Emtage, S. Gyorffy & J. Gauldie: Combined CXC chemokine and interleukin-12 gene transfer enhances antitumour immunity. Gene Ther 8, 282-290 (2001) (Pubitemid 32237061)
    • (2001) Gene Therapy , vol.8 , Issue.4 , pp. 282-290
    • Palmer, K.1    Hitt, M.2    Emtage, P.C.R.3    Gyorffy, S.4    Gauldie, J.5
  • 150
    • 16644384310 scopus 로고    scopus 로고
    • Expression of CXCL16 in human rectal cancer
    • Wagsater D., A. Hugander & J. Dimberg: Expression of CXCL16 in human rectal cancer. Int J Mol Med 14, 65-69 (2004)
    • (2004) Int J Mol Med , vol.14 , pp. 65-69
    • Wagsater, D.1    Hugander, A.2    Dimberg, J.3
  • 152
    • 0036772138 scopus 로고    scopus 로고
    • Metalloelastase (MMP-12) expression by tumour cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome
    • DOI 10.1002/path.1198
    • Kerkela E., R. Ala-aho, P. Klemi, S. Grenman, S. D. Shapiro, V. M. Kahari & U. Saarialho-Kere: Metalloelastase (MMP-12) expression by tumour cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome. J Pathol 198, 258-269 (2002) (Pubitemid 35243885)
    • (2002) Journal of Pathology , vol.198 , Issue.2 , pp. 258-269
    • Kerkela, E.1    Ala-aho, R.2    Klemi, P.3    Grenman, S.4    Shapiro, S.D.5    Kahari, V.-M.6    Saarialho-Kere, U.7
  • 155
    • 0034060430 scopus 로고    scopus 로고
    • Induction of potent antitumor response by vaccination with tumor lysate-pulsed macrophages engineered to secrete macrophage colony-stimulating factor and interferon-γ
    • Lei H., D. W. Ju, Y. Yu, Q. Tao, G. Chen, S. Gu, H. Hamada & X. Cao: Induction of potent antitumour response by vaccination with tumour lysate-pulsed macrophages engineered to secrete macrophage colonystimulating factor and interferon-gamma. Gene Ther 7, 707-713 (2000) (Pubitemid 30255776)
    • (2000) Gene Therapy , vol.7 , Issue.8 , pp. 707-713
    • Lei, H.1    Ju, D.W.2    Yu, Y.3    Tao, Q.4    Chen, G.5    Gu, S.6    Hamada, H.7    Cao, X.8
  • 156
    • 0031434098 scopus 로고    scopus 로고
    • Phase I trial of adoptive immunotherapy of cancer patients using monocyte-derived macrophages activated with Interferon γ and lipopolysaccharide
    • Hennemann B., G. Beckmann, A. Eichelmann, A. Rehm & R. Andreesen: Phase I trial of adoptive immunotherapy of cancer patients using monocyte-derived macrophages activated with interferon gamma and lipopolysaccharide. Cancer Immunol Immunother 45, 250-256 (1998) (Pubitemid 128759559)
    • (1998) Cancer Immunology, Immunotherapy , vol.45 , Issue.5 , pp. 250-256
    • Hennemann, B.1    Andreesen, R.2
  • 157
    • 0031691590 scopus 로고    scopus 로고
    • Adoptive immunotherapy of cancer using monocyte-derived macrophages: Rationale, current status, and perspectives
    • Andreesen R., B. Hennemann & S. W. Krause: Adoptive immunotherapy of cancer using monocytederived macrophages: rationale, current status and perspectives. J Leukoc Biol 64, 419-426 (1998) (Pubitemid 28455386)
    • (1998) Journal of Leukocyte Biology , vol.64 , Issue.4 , pp. 419-426
    • Andreesen, R.1    Hennemann, B.2    Krause, S.W.3
  • 160
    • 0037115528 scopus 로고    scopus 로고
    • Cancer-inducible transgene expression by the Grp94 promoter: Spontaneous activation in tumors of various origins and cancer-associated macrophages
    • Reddy R. K., L. Dubeau, H. Kleiner, T. Parr, P. Nichols, B. Ko, D. Dong, H. Ko, C. Mao, J. DiGiovanni & A. S. Lee: Cancer-inducible transgene expression by the Grp94 promoter: spontaneous activation in tumours of various origins and cancer-associated macrophages. Cancer Res 62, 7207-7212 (2002) (Pubitemid 36025240)
    • (2002) Cancer Research , vol.62 , Issue.24 , pp. 7207-7212
    • Reddy, R.K.1    Dubeau, L.2    Kleiner, H.3    Parr, T.4    Nichols, P.5    Ko, B.6    Dong, D.7    Ko, H.8    Mao, C.9    DiGiovanni, J.10    Lee, A.S.11
  • 161
    • 17144398046 scopus 로고    scopus 로고
    • Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection
    • Guiducci C., A. P. Vicari, S. Sangaletti, G. Trinchieri & M. P. Colombo: Redirecting in vivo elicited tumour infiltrating macrophages and dendritic cells towards tumour rejection. Cancer Res 65, 3437-3446 (2005) (Pubitemid 40524630)
    • (2005) Cancer Research , vol.65 , Issue.8 , pp. 3437-3446
    • Guiducci, C.1    Vicari, A.P.2    Sangaletti, S.3    Trinchieri, G.4    Colombo, M.P.5
  • 163
    • 33745950451 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ (PPARγ) ligands reverse CTL suppression by alternatively activated (M2) macrophages in cancer
    • DOI 10.1182/blood-2005-09-3777
    • Van Ginderachter J. A., S. Meerschaut, Y. Liu, L. Brys, K. De Groeve, G. Hassanzadeh-Ghassabeh, G. Raes & P. de Baetselier: Peroxisome proliferators-activated receptor gamma (PPARgamma) ligands reverse CTL suppression by alternatively activated (M2) macrophages in cancer. Blood 108, 525-535 (2006) (Pubitemid 44061352)
    • (2006) Blood , vol.108 , Issue.2 , pp. 525-535
    • Van Ginderachter, J.A.1    Meerschaut, S.2    Liu, Y.3    Brys, L.4    De Groeve, K.5    Ghassabeh, G.H.6    Raes, G.7    De Baetselier, P.8
  • 166
    • 0038408925 scopus 로고    scopus 로고
    • Mechanisms of macrophage cytotoxicity in IL-2 and IL-12 mediated tumour regression
    • Masztalerz A., N. van Rooijen, W. den Otter & L. A. Everse: Mechanisms of macrophage cytotoxicity in IL-2 and IL-12 mediated tumour regression. Cancer Immunol Immunother 52, 235-242 (2003) (Pubitemid 36535283)
    • (2003) Cancer Immunology, Immunotherapy , vol.52 , Issue.4 , pp. 235-242
    • Masztalerz, A.1    Van Rooijen, N.2    Den Otter, W.3    Everse, L.A.4
  • 167
    • 0033152004 scopus 로고    scopus 로고
    • Paclitaxel enhances macrophage IL-12 production in tumor-bearing hosts through nitric oxide
    • Mullins D. W., C. J. Burger & K. D. Elgert: Paclitaxel enhances macrophage IL-12 production in tumour-bearing hosts through nitric oxide. J Immunol 162, 6811-6818 (1999) (Pubitemid 29309409)
    • (1999) Journal of Immunology , vol.162 , Issue.11 , pp. 6811-6818
    • Mullins, D.W.1    Burger, C.J.2    Elgert, K.D.3
  • 168
    • 0036466861 scopus 로고    scopus 로고
    • Prolactin regulates antitumor immune response through induction of tumoricidal macrophages and release of IL-12
    • DOI 10.1002/ijc.1624
    • Majumder B., R. Biswas & U. Chattopadhyay: Prolactin regulates anttumour immune response through induction of tumouricidal macrophages and release of IL-12. Int J Cancer 97, 493-500 (2002) (Pubitemid 34027809)
    • (2002) International Journal of Cancer , vol.97 , Issue.4 , pp. 493-500
    • Majumder, B.1    Biswas, R.2    Chattopadhyay, U.3
  • 170
    • 33745078300 scopus 로고    scopus 로고
    • Tumour-associated macrophages are related to progression in patients with metastatic melanoma following interleukin-2 based immunotherapy
    • DOI 10.1080/02841860500471798, PII U818123338112651
    • Hansen B. D., H. Schmidt, H. von der Maase, P. Sioegren, R. Agger & M. Hokland: Tumour-associated macrophages are related to progression in patients with metastatic melanoma following interleukin-2 based immunotherapy. Acta Oncol 45, 400-405 (2006) (Pubitemid 43884607)
    • (2006) Acta Oncologica , vol.45 , Issue.4 , pp. 400-405
    • Hansen, B.D.1    Schmidt, H.2    Von Der Maase, H.3    Sjoegren, P.4    Agger, R.5    Hokland, M.6


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